Id |
Subject |
Object |
Predicate |
Lexical cue |
T17129 |
11-13 |
IN |
denotes |
In |
T17131 |
14-24 |
NN |
denotes |
conclusion |
T17132 |
24-26 |
, |
denotes |
, |
T17133 |
26-29 |
DT |
denotes |
the |
T17135 |
30-39 |
JJ |
denotes |
mammalian |
T17136 |
40-45 |
NN |
denotes |
Pygo2 |
T17134 |
46-50 |
NN |
denotes |
gene |
T17137 |
51-53 |
VBZ |
denotes |
is |
T17130 |
54-62 |
VBN |
denotes |
required |
T17138 |
63-66 |
IN |
denotes |
for |
T17139 |
67-73 |
JJ |
denotes |
normal |
T17141 |
74-83 |
NN |
denotes |
branching |
T17140 |
84-97 |
NN |
denotes |
morphogenesis |
T17142 |
98-100 |
IN |
denotes |
of |
T17143 |
101-104 |
DT |
denotes |
the |
T17145 |
105-113 |
JJ |
denotes |
ureteric |
T17144 |
114-117 |
NN |
denotes |
bud |
T17146 |
117-119 |
, |
denotes |
, |
T17147 |
119-123 |
IN |
denotes |
with |
T17148 |
124-131 |
NNS |
denotes |
mutants |
T17149 |
132-139 |
VBG |
denotes |
showing |
T17150 |
140-147 |
VBN |
denotes |
dilated |
T17151 |
148-152 |
NNS |
denotes |
tips |
T17152 |
153-156 |
CC |
denotes |
and |
T17153 |
157-164 |
VBN |
denotes |
reduced |
T17154 |
165-172 |
NNS |
denotes |
numbers |
T17155 |
173-175 |
IN |
denotes |
of |
T17156 |
176-180 |
NNS |
denotes |
tips |
T17157 |
180-181 |
. |
denotes |
. |
T17158 |
181-301 |
sentence |
denotes |
In addition, in Pygo2 mutants there was an expansion of the zone of metanephric mesenchyme that caps the ureteric buds. |
T17159 |
182-184 |
IN |
denotes |
In |
T17161 |
185-193 |
NN |
denotes |
addition |
T17162 |
193-195 |
, |
denotes |
, |
T17163 |
195-197 |
IN |
denotes |
in |
T17164 |
198-203 |
NN |
denotes |
Pygo2 |
T17165 |
204-211 |
NNS |
denotes |
mutants |
T17166 |
212-217 |
EX |
denotes |
there |
T17160 |
218-221 |
VBD |
denotes |
was |
T17167 |
222-224 |
DT |
denotes |
an |
T17168 |
225-234 |
NN |
denotes |
expansion |
T17169 |
235-237 |
IN |
denotes |
of |
T17170 |
238-241 |
DT |
denotes |
the |
T17171 |
242-246 |
NN |
denotes |
zone |
T17172 |
247-249 |
IN |
denotes |
of |
T17173 |
250-261 |
JJ |
denotes |
metanephric |
T17174 |
262-272 |
NN |
denotes |
mesenchyme |
T17175 |
273-277 |
WDT |
denotes |
that |
T17176 |
278-282 |
VBZ |
denotes |
caps |
T17177 |
283-286 |
DT |
denotes |
the |
T17179 |
287-295 |
JJ |
denotes |
ureteric |
T17178 |
296-300 |
NNS |
denotes |
buds |
T17180 |
300-301 |
. |
denotes |
. |
T17181 |
301-411 |
sentence |
denotes |
Nevertheless, nephron formation proceeded remarkably normally, even in Pygo1/Pygo2 double-homozygous mutants. |
T17182 |
302-314 |
RB |
denotes |
Nevertheless |
T17184 |
314-316 |
, |
denotes |
, |
T17185 |
316-323 |
NN |
denotes |
nephron |
T17186 |
324-333 |
NN |
denotes |
formation |
T17183 |
334-343 |
VBD |
denotes |
proceeded |
T17187 |
344-354 |
RB |
denotes |
remarkably |
T17188 |
355-363 |
RB |
denotes |
normally |
T17189 |
363-365 |
, |
denotes |
, |
T17190 |
365-369 |
RB |
denotes |
even |
T17191 |
370-372 |
IN |
denotes |
in |
T17192 |
373-378 |
NN |
denotes |
Pygo1 |
T17194 |
378-379 |
HYPH |
denotes |
/ |
T17193 |
379-384 |
NN |
denotes |
Pygo2 |
T17196 |
385-391 |
JJ |
denotes |
double |
T17197 |
391-392 |
HYPH |
denotes |
- |
T17195 |
392-402 |
JJ |
denotes |
homozygous |
T17198 |
403-410 |
NNS |
denotes |
mutants |
T17199 |
410-411 |
. |
denotes |
. |
T17200 |
411-584 |
sentence |
denotes |
This was surprising considering the importance of the Pygopus gene in canonical Wnt signaling in Drosophila, and the importance of canonical Wnt signaling in nephrogenesis. |
T17201 |
412-416 |
DT |
denotes |
This |
T17202 |
417-420 |
VBD |
denotes |
was |
T17203 |
421-431 |
JJ |
denotes |
surprising |
T17204 |
432-443 |
VBG |
denotes |
considering |
T17205 |
444-447 |
DT |
denotes |
the |
T17206 |
448-458 |
NN |
denotes |
importance |
T17207 |
459-461 |
IN |
denotes |
of |
T17208 |
462-465 |
DT |
denotes |
the |
T17210 |
466-473 |
NN |
denotes |
Pygopus |
T17209 |
474-478 |
NN |
denotes |
gene |
T17211 |
479-481 |
IN |
denotes |
in |
T17212 |
482-491 |
JJ |
denotes |
canonical |
T17214 |
492-495 |
NN |
denotes |
Wnt |
T17213 |
496-505 |
NN |
denotes |
signaling |
T17215 |
506-508 |
IN |
denotes |
in |
T17216 |
509-519 |
NNP |
denotes |
Drosophila |
T17217 |
519-521 |
, |
denotes |
, |
T17218 |
521-524 |
CC |
denotes |
and |
T17219 |
525-528 |
DT |
denotes |
the |
T17220 |
529-539 |
NN |
denotes |
importance |
T17221 |
540-542 |
IN |
denotes |
of |
T17222 |
543-552 |
JJ |
denotes |
canonical |
T17224 |
553-556 |
NN |
denotes |
Wnt |
T17223 |
557-566 |
NN |
denotes |
signaling |
T17225 |
567-569 |
IN |
denotes |
in |
T17226 |
570-583 |
NN |
denotes |
nephrogenesis |
T17227 |
583-584 |
. |
denotes |
. |
T17228 |
584-716 |
sentence |
denotes |
The results argue that the mammalian Pygopus genes are, in most developing systems, only quantitative transducers of Wnt signaling. |
T17229 |
585-588 |
DT |
denotes |
The |
T17230 |
589-596 |
NNS |
denotes |
results |
T17231 |
597-602 |
VBP |
denotes |
argue |
T17232 |
603-607 |
IN |
denotes |
that |
T17234 |
608-611 |
DT |
denotes |
the |
T17236 |
612-621 |
JJ |
denotes |
mammalian |
T17237 |
622-629 |
NN |
denotes |
Pygopus |
T17235 |
630-635 |
NNS |
denotes |
genes |
T17233 |
636-639 |
VBP |
denotes |
are |
T17238 |
639-641 |
, |
denotes |
, |
T17239 |
641-643 |
IN |
denotes |
in |
T17240 |
644-648 |
JJS |
denotes |
most |
T17242 |
649-659 |
VBG |
denotes |
developing |
T17241 |
660-667 |
NNS |
denotes |
systems |
T17243 |
667-669 |
, |
denotes |
, |
T17244 |
669-673 |
RB |
denotes |
only |
T17246 |
674-686 |
JJ |
denotes |
quantitative |
T17245 |
687-698 |
NNS |
denotes |
transducers |
T17247 |
699-701 |
IN |
denotes |
of |
T17248 |
702-705 |
NN |
denotes |
Wnt |
T17249 |
706-715 |
NN |
denotes |
signaling |
T17250 |
715-716 |
. |
denotes |
. |
T17251 |
716-943 |
sentence |
denotes |
Previous cell culture studies [32,33] and the reduced BAT-gal transgene reporter expression in the Pygo1/Pygo2 knockout mice described in this report, do confirm an evolutionarily conserved function in canonical Wnt signaling. |
T17252 |
717-725 |
JJ |
denotes |
Previous |
T17254 |
726-730 |
NN |
denotes |
cell |
T17255 |
731-738 |
NN |
denotes |
culture |
T17253 |
739-746 |
NNS |
denotes |
studies |
T17257 |
747-748 |
-LRB- |
denotes |
[ |
T17259 |
748-750 |
CD |
denotes |
32 |
T17260 |
750-751 |
, |
denotes |
, |
T17258 |
751-753 |
CD |
denotes |
33 |
T17261 |
753-754 |
-RRB- |
denotes |
] |
T17262 |
755-758 |
CC |
denotes |
and |
T17263 |
759-762 |
DT |
denotes |
the |
T17265 |
763-770 |
VBN |
denotes |
reduced |
T17266 |
771-774 |
NN |
denotes |
BAT |
T17268 |
774-775 |
HYPH |
denotes |
- |
T17267 |
775-778 |
NN |
denotes |
gal |
T17269 |
779-788 |
NN |
denotes |
transgene |
T17270 |
789-797 |
NN |
denotes |
reporter |
T17264 |
798-808 |
NN |
denotes |
expression |
T17271 |
809-811 |
IN |
denotes |
in |
T17272 |
812-815 |
DT |
denotes |
the |
T17274 |
816-821 |
NN |
denotes |
Pygo1 |
T17276 |
821-822 |
HYPH |
denotes |
/ |
T17275 |
822-827 |
NN |
denotes |
Pygo2 |
T17277 |
828-836 |
NN |
denotes |
knockout |
T17273 |
837-841 |
NNS |
denotes |
mice |
T17278 |
842-851 |
VBN |
denotes |
described |
T17279 |
852-854 |
IN |
denotes |
in |
T17280 |
855-859 |
DT |
denotes |
this |
T17281 |
860-866 |
NN |
denotes |
report |
T17282 |
866-868 |
, |
denotes |
, |
T17283 |
868-870 |
VBP |
denotes |
do |
T17256 |
871-878 |
VB |
denotes |
confirm |
T17284 |
879-881 |
DT |
denotes |
an |
T17286 |
882-896 |
RB |
denotes |
evolutionarily |
T17287 |
897-906 |
VBN |
denotes |
conserved |
T17285 |
907-915 |
NN |
denotes |
function |
T17288 |
916-918 |
IN |
denotes |
in |
T17289 |
919-928 |
JJ |
denotes |
canonical |
T17291 |
929-932 |
NN |
denotes |
Wnt |
T17290 |
933-942 |
NN |
denotes |
signaling |
T17292 |
942-943 |
. |
denotes |
. |
T17293 |
943-1043 |
sentence |
denotes |
In mammals, however, the phenotypic effects of Pygopus mutation are much milder than in Drosophila. |
T17294 |
944-946 |
IN |
denotes |
In |
T17296 |
947-954 |
NNS |
denotes |
mammals |
T17297 |
954-956 |
, |
denotes |
, |
T17298 |
956-963 |
RB |
denotes |
however |
T17299 |
963-965 |
, |
denotes |
, |
T17300 |
965-968 |
DT |
denotes |
the |
T17302 |
969-979 |
JJ |
denotes |
phenotypic |
T17301 |
980-987 |
NNS |
denotes |
effects |
T17303 |
988-990 |
IN |
denotes |
of |
T17304 |
991-998 |
NN |
denotes |
Pygopus |
T17305 |
999-1007 |
NN |
denotes |
mutation |
T17295 |
1008-1011 |
VBP |
denotes |
are |
T17306 |
1012-1016 |
RB |
denotes |
much |
T17307 |
1017-1023 |
JJR |
denotes |
milder |
T17308 |
1024-1028 |
IN |
denotes |
than |
T17309 |
1029-1031 |
IN |
denotes |
in |
T17310 |
1032-1042 |
NNP |
denotes |
Drosophila |
T17311 |
1042-1043 |
. |
denotes |
. |
T17312 |
1043-1204 |
sentence |
denotes |
The degree of importance of the Pyg1/2 genes in Wnt signaling was context-dependent, but in general, mammalian organogenesis remained intact in Pygopus mutants. |
T17313 |
1044-1047 |
DT |
denotes |
The |
T17314 |
1048-1054 |
NN |
denotes |
degree |
T17316 |
1055-1057 |
IN |
denotes |
of |
T17317 |
1058-1068 |
NN |
denotes |
importance |
T17318 |
1069-1071 |
IN |
denotes |
of |
T17319 |
1072-1075 |
DT |
denotes |
the |
T17321 |
1076-1080 |
NN |
denotes |
Pyg1 |
T17322 |
1080-1081 |
HYPH |
denotes |
/ |
T17323 |
1081-1082 |
CD |
denotes |
2 |
T17320 |
1083-1088 |
NNS |
denotes |
genes |
T17324 |
1089-1091 |
IN |
denotes |
in |
T17325 |
1092-1095 |
NN |
denotes |
Wnt |
T17326 |
1096-1105 |
NN |
denotes |
signaling |
T17315 |
1106-1109 |
VBD |
denotes |
was |
T17327 |
1110-1117 |
NN |
denotes |
context |
T17329 |
1117-1118 |
HYPH |
denotes |
- |
T17328 |
1118-1127 |
JJ |
denotes |
dependent |
T17330 |
1127-1129 |
, |
denotes |
, |
T17331 |
1129-1132 |
CC |
denotes |
but |
T17332 |
1133-1135 |
IN |
denotes |
in |
T17334 |
1136-1143 |
JJ |
denotes |
general |
T17335 |
1143-1145 |
, |
denotes |
, |
T17336 |
1145-1154 |
JJ |
denotes |
mammalian |
T17337 |
1155-1168 |
NN |
denotes |
organogenesis |
T17333 |
1169-1177 |
VBD |
denotes |
remained |
T17338 |
1178-1184 |
JJ |
denotes |
intact |
T17339 |
1185-1187 |
IN |
denotes |
in |
T17340 |
1188-1195 |
NNP |
denotes |
Pygopus |
T17341 |
1196-1203 |
NNS |
denotes |
mutants |
T17342 |
1203-1204 |
. |
denotes |
. |
T17343 |
1204-1332 |
sentence |
denotes |
Perhaps the simplest explanation is that in mammals, other genes show partial functional redundancy with the two Pygopus genes. |
T17344 |
1205-1212 |
RB |
denotes |
Perhaps |
T17346 |
1213-1216 |
DT |
denotes |
the |
T17348 |
1217-1225 |
JJS |
denotes |
simplest |
T17347 |
1226-1237 |
NN |
denotes |
explanation |
T17345 |
1238-1240 |
VBZ |
denotes |
is |
T17349 |
1241-1245 |
IN |
denotes |
that |
T17351 |
1246-1248 |
IN |
denotes |
in |
T17352 |
1249-1256 |
NNS |
denotes |
mammals |
T17353 |
1256-1258 |
, |
denotes |
, |
T17354 |
1258-1263 |
JJ |
denotes |
other |
T17355 |
1264-1269 |
NNS |
denotes |
genes |
T17350 |
1270-1274 |
VBP |
denotes |
show |
T17356 |
1275-1282 |
JJ |
denotes |
partial |
T17358 |
1283-1293 |
JJ |
denotes |
functional |
T17357 |
1294-1304 |
NN |
denotes |
redundancy |
T17359 |
1305-1309 |
IN |
denotes |
with |
T17360 |
1310-1313 |
DT |
denotes |
the |
T17362 |
1314-1317 |
CD |
denotes |
two |
T17363 |
1318-1325 |
NN |
denotes |
Pygopus |
T17361 |
1326-1331 |
NNS |
denotes |
genes |
T17364 |
1331-1332 |
. |
denotes |
. |
T17365 |
1332-1543 |
sentence |
denotes |
The β-catenin transcription-factor complex includes a large and growing number of proteins , some of which may share the nuclear localization and/or transcription activation functions of Pygo1/Pygo2 in mammals. |
T17366 |
1333-1336 |
DT |
denotes |
The |
T17368 |
1337-1338 |
NN |
denotes |
β |
T17370 |
1338-1339 |
HYPH |
denotes |
- |
T17369 |
1339-1346 |
NN |
denotes |
catenin |
T17371 |
1347-1360 |
NN |
denotes |
transcription |
T17373 |
1360-1361 |
HYPH |
denotes |
- |
T17372 |
1361-1367 |
NN |
denotes |
factor |
T17367 |
1368-1375 |
NN |
denotes |
complex |
T17374 |
1376-1384 |
VBZ |
denotes |
includes |
T17375 |
1385-1386 |
DT |
denotes |
a |
T17377 |
1387-1392 |
JJ |
denotes |
large |
T17378 |
1393-1396 |
CC |
denotes |
and |
T17379 |
1397-1404 |
VBG |
denotes |
growing |
T17376 |
1405-1411 |
NN |
denotes |
number |
T17380 |
1412-1414 |
IN |
denotes |
of |
T17381 |
1415-1423 |
NN |
denotes |
proteins |
T17382 |
1424-1426 |
, |
denotes |
, |
T17383 |
1426-1430 |
DT |
denotes |
some |
T17385 |
1431-1433 |
IN |
denotes |
of |
T17386 |
1434-1439 |
WDT |
denotes |
which |
T17387 |
1440-1443 |
MD |
denotes |
may |
T17384 |
1444-1449 |
VB |
denotes |
share |
T17388 |
1450-1453 |
DT |
denotes |
the |
T17390 |
1454-1461 |
JJ |
denotes |
nuclear |
T17391 |
1462-1474 |
NN |
denotes |
localization |
T17392 |
1475-1478 |
CC |
denotes |
and |
T17393 |
1478-1479 |
HYPH |
denotes |
/ |
T17394 |
1479-1481 |
CC |
denotes |
or |
T17395 |
1482-1495 |
NN |
denotes |
transcription |
T17396 |
1496-1506 |
NN |
denotes |
activation |
T17389 |
1507-1516 |
NNS |
denotes |
functions |
T17397 |
1517-1519 |
IN |
denotes |
of |
T17398 |
1520-1525 |
NN |
denotes |
Pygo1 |
T17400 |
1525-1526 |
HYPH |
denotes |
/ |
T17399 |
1526-1531 |
NN |
denotes |
Pygo2 |
T17401 |
1532-1534 |
IN |
denotes |
in |
T17402 |
1535-1542 |
NNS |
denotes |
mammals |
T17403 |
1542-1543 |
. |
denotes |
. |
T17404 |
1543-1626 |
sentence |
denotes |
The identities and roles of these Pygopus redundant genes remain to be determined. |
T17405 |
1544-1547 |
DT |
denotes |
The |
T17406 |
1548-1558 |
NNS |
denotes |
identities |
T17408 |
1559-1562 |
CC |
denotes |
and |
T17409 |
1563-1568 |
NNS |
denotes |
roles |
T17410 |
1569-1571 |
IN |
denotes |
of |
T17411 |
1572-1577 |
DT |
denotes |
these |
T17413 |
1578-1585 |
NN |
denotes |
Pygopus |
T17414 |
1586-1595 |
JJ |
denotes |
redundant |
T17412 |
1596-1601 |
NNS |
denotes |
genes |
T17407 |
1602-1608 |
VBP |
denotes |
remain |
T17415 |
1609-1611 |
TO |
denotes |
to |
T17417 |
1612-1614 |
VB |
denotes |
be |
T17416 |
1615-1625 |
VBN |
denotes |
determined |
T17418 |
1625-1626 |
. |
denotes |
. |
R4723 |
T17129 |
T17130 |
prep |
In,required |
R4724 |
T17131 |
T17129 |
pobj |
conclusion,In |
R4725 |
T17132 |
T17130 |
punct |
", ",required |
R4726 |
T17133 |
T17134 |
det |
the,gene |
R4727 |
T17134 |
T17130 |
nsubjpass |
gene,required |
R4728 |
T17135 |
T17134 |
amod |
mammalian,gene |
R4729 |
T17136 |
T17134 |
compound |
Pygo2,gene |
R4730 |
T17137 |
T17130 |
auxpass |
is,required |
R4731 |
T17138 |
T17130 |
prep |
for,required |
R4732 |
T17139 |
T17140 |
amod |
normal,morphogenesis |
R4733 |
T17140 |
T17138 |
pobj |
morphogenesis,for |
R4734 |
T17141 |
T17140 |
compound |
branching,morphogenesis |
R4735 |
T17142 |
T17140 |
prep |
of,morphogenesis |
R4736 |
T17143 |
T17144 |
det |
the,bud |
R4737 |
T17144 |
T17142 |
pobj |
bud,of |
R4738 |
T17145 |
T17144 |
amod |
ureteric,bud |
R4739 |
T17146 |
T17130 |
punct |
", ",required |
R4740 |
T17147 |
T17130 |
prep |
with,required |
R4741 |
T17148 |
T17149 |
nsubj |
mutants,showing |
R4742 |
T17149 |
T17147 |
pcomp |
showing,with |
R4743 |
T17150 |
T17151 |
amod |
dilated,tips |
R4744 |
T17151 |
T17149 |
dobj |
tips,showing |
R4745 |
T17152 |
T17151 |
cc |
and,tips |
R4746 |
T17153 |
T17154 |
amod |
reduced,numbers |
R4747 |
T17154 |
T17151 |
conj |
numbers,tips |
R4748 |
T17155 |
T17154 |
prep |
of,numbers |
R4749 |
T17156 |
T17155 |
pobj |
tips,of |
R4750 |
T17157 |
T17130 |
punct |
.,required |
R4751 |
T17159 |
T17160 |
prep |
In,was |
R4752 |
T17161 |
T17159 |
pobj |
addition,In |
R4753 |
T17162 |
T17160 |
punct |
", ",was |
R4754 |
T17163 |
T17160 |
prep |
in,was |
R4755 |
T17164 |
T17165 |
compound |
Pygo2,mutants |
R4756 |
T17165 |
T17163 |
pobj |
mutants,in |
R4757 |
T17166 |
T17160 |
expl |
there,was |
R4758 |
T17167 |
T17168 |
det |
an,expansion |
R4759 |
T17168 |
T17160 |
attr |
expansion,was |
R4760 |
T17169 |
T17168 |
prep |
of,expansion |
R4761 |
T17170 |
T17171 |
det |
the,zone |
R4762 |
T17171 |
T17169 |
pobj |
zone,of |
R4763 |
T17172 |
T17171 |
prep |
of,zone |
R4764 |
T17173 |
T17174 |
amod |
metanephric,mesenchyme |
R4765 |
T17174 |
T17172 |
pobj |
mesenchyme,of |
R4766 |
T17175 |
T17176 |
dep |
that,caps |
R4767 |
T17176 |
T17171 |
relcl |
caps,zone |
R4768 |
T17177 |
T17178 |
det |
the,buds |
R4769 |
T17178 |
T17176 |
dobj |
buds,caps |
R4770 |
T17179 |
T17178 |
amod |
ureteric,buds |
R4771 |
T17180 |
T17160 |
punct |
.,was |
R4772 |
T17182 |
T17183 |
advmod |
Nevertheless,proceeded |
R4773 |
T17184 |
T17183 |
punct |
", ",proceeded |
R4774 |
T17185 |
T17186 |
compound |
nephron,formation |
R4775 |
T17186 |
T17183 |
nsubj |
formation,proceeded |
R4776 |
T17187 |
T17188 |
advmod |
remarkably,normally |
R4777 |
T17188 |
T17183 |
advmod |
normally,proceeded |
R4778 |
T17189 |
T17183 |
punct |
", ",proceeded |
R4779 |
T17190 |
T17191 |
advmod |
even,in |
R4780 |
T17191 |
T17183 |
prep |
in,proceeded |
R4781 |
T17192 |
T17193 |
compound |
Pygo1,Pygo2 |
R4782 |
T17193 |
T17195 |
npadvmod |
Pygo2,homozygous |
R4783 |
T17194 |
T17193 |
punct |
/,Pygo2 |
R4784 |
T17195 |
T17198 |
amod |
homozygous,mutants |
R4785 |
T17196 |
T17195 |
amod |
double,homozygous |
R4786 |
T17197 |
T17195 |
punct |
-,homozygous |
R4787 |
T17198 |
T17191 |
pobj |
mutants,in |
R4788 |
T17199 |
T17183 |
punct |
.,proceeded |
R4789 |
T17201 |
T17202 |
nsubj |
This,was |
R4790 |
T17203 |
T17202 |
acomp |
surprising,was |
R4791 |
T17204 |
T17202 |
advcl |
considering,was |
R4792 |
T17205 |
T17206 |
det |
the,importance |
R4793 |
T17206 |
T17204 |
dobj |
importance,considering |
R4794 |
T17207 |
T17206 |
prep |
of,importance |
R4795 |
T17208 |
T17209 |
det |
the,gene |
R4796 |
T17209 |
T17207 |
pobj |
gene,of |
R4797 |
T17210 |
T17209 |
compound |
Pygopus,gene |
R4798 |
T17211 |
T17206 |
prep |
in,importance |
R4799 |
T17212 |
T17213 |
amod |
canonical,signaling |
R4800 |
T17213 |
T17211 |
pobj |
signaling,in |
R4801 |
T17214 |
T17213 |
compound |
Wnt,signaling |
R4802 |
T17215 |
T17206 |
prep |
in,importance |
R4803 |
T17216 |
T17215 |
pobj |
Drosophila,in |
R4804 |
T17217 |
T17206 |
punct |
", ",importance |
R4805 |
T17218 |
T17206 |
cc |
and,importance |
R4806 |
T17219 |
T17220 |
det |
the,importance |
R4807 |
T17220 |
T17206 |
conj |
importance,importance |
R4808 |
T17221 |
T17220 |
prep |
of,importance |
R4809 |
T17222 |
T17223 |
amod |
canonical,signaling |
R4810 |
T17223 |
T17221 |
pobj |
signaling,of |
R4811 |
T17224 |
T17223 |
compound |
Wnt,signaling |
R4812 |
T17225 |
T17220 |
prep |
in,importance |
R4813 |
T17226 |
T17225 |
pobj |
nephrogenesis,in |
R4814 |
T17227 |
T17202 |
punct |
.,was |
R4815 |
T17229 |
T17230 |
det |
The,results |
R4816 |
T17230 |
T17231 |
nsubj |
results,argue |
R4817 |
T17232 |
T17233 |
mark |
that,are |
R4818 |
T17233 |
T17231 |
ccomp |
are,argue |
R4819 |
T17234 |
T17235 |
det |
the,genes |
R4820 |
T17235 |
T17233 |
nsubj |
genes,are |
R4821 |
T17236 |
T17235 |
amod |
mammalian,genes |
R4822 |
T17237 |
T17235 |
compound |
Pygopus,genes |
R4823 |
T17238 |
T17233 |
punct |
", ",are |
R4824 |
T17239 |
T17233 |
prep |
in,are |
R4825 |
T17240 |
T17241 |
amod |
most,systems |
R4826 |
T17241 |
T17239 |
pobj |
systems,in |
R4827 |
T17242 |
T17241 |
amod |
developing,systems |
R4828 |
T17243 |
T17233 |
punct |
", ",are |
R4829 |
T17244 |
T17245 |
advmod |
only,transducers |
R4830 |
T17245 |
T17233 |
attr |
transducers,are |
R4831 |
T17246 |
T17245 |
amod |
quantitative,transducers |
R4832 |
T17247 |
T17245 |
prep |
of,transducers |
R4833 |
T17248 |
T17249 |
compound |
Wnt,signaling |
R4834 |
T17249 |
T17247 |
pobj |
signaling,of |
R4835 |
T17250 |
T17231 |
punct |
.,argue |
R4836 |
T17252 |
T17253 |
amod |
Previous,studies |
R4837 |
T17253 |
T17256 |
nsubj |
studies,confirm |
R4838 |
T17254 |
T17255 |
compound |
cell,culture |
R4839 |
T17255 |
T17253 |
compound |
culture,studies |
R4840 |
T17257 |
T17258 |
punct |
[,33 |
R4841 |
T17258 |
T17253 |
parataxis |
33,studies |
R4842 |
T17259 |
T17258 |
nummod |
32,33 |
R4843 |
T17260 |
T17258 |
punct |
",",33 |
R4844 |
T17261 |
T17258 |
punct |
],33 |
R4845 |
T17262 |
T17253 |
cc |
and,studies |
R4846 |
T17263 |
T17264 |
det |
the,expression |
R4847 |
T17264 |
T17253 |
conj |
expression,studies |
R4848 |
T17265 |
T17264 |
amod |
reduced,expression |
R4849 |
T17266 |
T17267 |
compound |
BAT,gal |
R4850 |
T17267 |
T17269 |
compound |
gal,transgene |
R4851 |
T17268 |
T17267 |
punct |
-,gal |
R4852 |
T17269 |
T17270 |
compound |
transgene,reporter |
R4853 |
T17270 |
T17264 |
compound |
reporter,expression |
R4854 |
T17271 |
T17253 |
prep |
in,studies |
R4855 |
T17272 |
T17273 |
det |
the,mice |
R4856 |
T17273 |
T17271 |
pobj |
mice,in |
R4857 |
T17274 |
T17275 |
compound |
Pygo1,Pygo2 |
R4858 |
T17275 |
T17277 |
compound |
Pygo2,knockout |
R4859 |
T17276 |
T17275 |
punct |
/,Pygo2 |
R4860 |
T17277 |
T17273 |
compound |
knockout,mice |
R4861 |
T17278 |
T17273 |
acl |
described,mice |
R4862 |
T17279 |
T17278 |
prep |
in,described |
R4863 |
T17280 |
T17281 |
det |
this,report |
R4864 |
T17281 |
T17279 |
pobj |
report,in |
R4865 |
T17282 |
T17256 |
punct |
", ",confirm |
R4866 |
T17283 |
T17256 |
aux |
do,confirm |
R4867 |
T17284 |
T17285 |
det |
an,function |
R4868 |
T17285 |
T17256 |
dobj |
function,confirm |
R4869 |
T17286 |
T17287 |
advmod |
evolutionarily,conserved |
R4870 |
T17287 |
T17285 |
amod |
conserved,function |
R4871 |
T17288 |
T17285 |
prep |
in,function |
R4872 |
T17289 |
T17290 |
amod |
canonical,signaling |
R4873 |
T17290 |
T17288 |
pobj |
signaling,in |
R4874 |
T17291 |
T17290 |
compound |
Wnt,signaling |
R4875 |
T17292 |
T17256 |
punct |
.,confirm |
R4876 |
T17294 |
T17295 |
prep |
In,are |
R4877 |
T17296 |
T17294 |
pobj |
mammals,In |
R4878 |
T17297 |
T17295 |
punct |
", ",are |
R4879 |
T17298 |
T17295 |
advmod |
however,are |
R4880 |
T17299 |
T17295 |
punct |
", ",are |
R4881 |
T17300 |
T17301 |
det |
the,effects |
R4882 |
T17301 |
T17295 |
nsubj |
effects,are |
R4883 |
T17302 |
T17301 |
amod |
phenotypic,effects |
R4884 |
T17303 |
T17301 |
prep |
of,effects |
R4885 |
T17304 |
T17305 |
compound |
Pygopus,mutation |
R4886 |
T17305 |
T17303 |
pobj |
mutation,of |
R4887 |
T17306 |
T17307 |
advmod |
much,milder |
R4888 |
T17307 |
T17295 |
acomp |
milder,are |
R4889 |
T17308 |
T17307 |
prep |
than,milder |
R4890 |
T17309 |
T17308 |
prep |
in,than |
R4891 |
T17310 |
T17309 |
pobj |
Drosophila,in |
R4892 |
T17311 |
T17295 |
punct |
.,are |
R4893 |
T17313 |
T17314 |
det |
The,degree |
R4894 |
T17314 |
T17315 |
nsubj |
degree,was |
R4895 |
T17316 |
T17314 |
prep |
of,degree |
R4896 |
T17317 |
T17316 |
pobj |
importance,of |
R4897 |
T17318 |
T17317 |
prep |
of,importance |
R4898 |
T17319 |
T17320 |
det |
the,genes |
R4899 |
T17320 |
T17318 |
pobj |
genes,of |
R4900 |
T17321 |
T17320 |
nmod |
Pyg1,genes |
R4901 |
T17322 |
T17321 |
punct |
/,Pyg1 |
R4902 |
T17323 |
T17321 |
nummod |
2,Pyg1 |
R4903 |
T17324 |
T17314 |
prep |
in,degree |
R4904 |
T17325 |
T17326 |
compound |
Wnt,signaling |
R4905 |
T17326 |
T17324 |
pobj |
signaling,in |
R4906 |
T17327 |
T17328 |
npadvmod |
context,dependent |
R4907 |
T17328 |
T17315 |
acomp |
dependent,was |
R4908 |
T17329 |
T17328 |
punct |
-,dependent |
R4909 |
T17330 |
T17315 |
punct |
", ",was |
R4910 |
T17331 |
T17315 |
cc |
but,was |
R4911 |
T17332 |
T17333 |
prep |
in,remained |
R4912 |
T17333 |
T17315 |
conj |
remained,was |
R4913 |
T17334 |
T17332 |
amod |
general,in |
R4914 |
T17335 |
T17333 |
punct |
", ",remained |
R4915 |
T17336 |
T17337 |
amod |
mammalian,organogenesis |
R4916 |
T17337 |
T17333 |
nsubj |
organogenesis,remained |
R4917 |
T17338 |
T17333 |
acomp |
intact,remained |
R4918 |
T17339 |
T17333 |
prep |
in,remained |
R4919 |
T17340 |
T17341 |
compound |
Pygopus,mutants |
R4920 |
T17341 |
T17339 |
pobj |
mutants,in |
R4921 |
T17342 |
T17333 |
punct |
.,remained |
R4922 |
T17344 |
T17345 |
advmod |
Perhaps,is |
R4923 |
T17346 |
T17347 |
det |
the,explanation |
R4924 |
T17347 |
T17345 |
nsubj |
explanation,is |
R4925 |
T17348 |
T17347 |
amod |
simplest,explanation |
R4926 |
T17349 |
T17350 |
mark |
that,show |
R4927 |
T17350 |
T17345 |
ccomp |
show,is |
R4928 |
T17351 |
T17350 |
prep |
in,show |
R4929 |
T17352 |
T17351 |
pobj |
mammals,in |
R4930 |
T17353 |
T17350 |
punct |
", ",show |
R4931 |
T17354 |
T17355 |
amod |
other,genes |
R4932 |
T17355 |
T17350 |
nsubj |
genes,show |
R4933 |
T17356 |
T17357 |
amod |
partial,redundancy |
R4934 |
T17357 |
T17350 |
dobj |
redundancy,show |
R4935 |
T17358 |
T17357 |
amod |
functional,redundancy |
R4936 |
T17359 |
T17357 |
prep |
with,redundancy |
R4937 |
T17360 |
T17361 |
det |
the,genes |
R4938 |
T17361 |
T17359 |
pobj |
genes,with |
R4939 |
T17362 |
T17361 |
nummod |
two,genes |
R4940 |
T17363 |
T17361 |
compound |
Pygopus,genes |
R4941 |
T17364 |
T17345 |
punct |
.,is |
R4942 |
T17366 |
T17367 |
det |
The,complex |
R4943 |
T17367 |
T17374 |
nsubj |
complex,includes |
R4944 |
T17368 |
T17369 |
compound |
β,catenin |
R4945 |
T17369 |
T17367 |
compound |
catenin,complex |
R4946 |
T17370 |
T17369 |
punct |
-,catenin |
R4947 |
T17371 |
T17372 |
compound |
transcription,factor |
R4948 |
T17372 |
T17367 |
compound |
factor,complex |
R4949 |
T17373 |
T17372 |
punct |
-,factor |
R4950 |
T17375 |
T17376 |
det |
a,number |
R4951 |
T17376 |
T17374 |
dobj |
number,includes |
R4952 |
T17377 |
T17376 |
amod |
large,number |
R4953 |
T17378 |
T17377 |
cc |
and,large |
R4954 |
T17379 |
T17377 |
conj |
growing,large |
R4955 |
T17380 |
T17376 |
prep |
of,number |
R4956 |
T17381 |
T17380 |
pobj |
proteins,of |
R4957 |
T17382 |
T17381 |
punct |
", ",proteins |
R4958 |
T17383 |
T17384 |
dep |
some,share |
R4959 |
T17384 |
T17381 |
relcl |
share,proteins |
R4960 |
T17385 |
T17383 |
prep |
of,some |
R4961 |
T17386 |
T17385 |
pobj |
which,of |
R4962 |
T17387 |
T17384 |
aux |
may,share |
R4963 |
T17388 |
T17389 |
det |
the,functions |
R4964 |
T17389 |
T17384 |
dobj |
functions,share |
R4965 |
T17390 |
T17391 |
amod |
nuclear,localization |
R4966 |
T17391 |
T17389 |
nmod |
localization,functions |
R4967 |
T17392 |
T17391 |
cc |
and,localization |
R4968 |
T17393 |
T17392 |
punct |
/,and |
R4969 |
T17394 |
T17392 |
cc |
or,and |
R4970 |
T17395 |
T17396 |
compound |
transcription,activation |
R4971 |
T17396 |
T17391 |
conj |
activation,localization |
R4972 |
T17397 |
T17389 |
prep |
of,functions |
R4973 |
T17398 |
T17399 |
compound |
Pygo1,Pygo2 |
R4974 |
T17399 |
T17397 |
pobj |
Pygo2,of |
R4975 |
T17400 |
T17399 |
punct |
/,Pygo2 |
R4976 |
T17401 |
T17389 |
prep |
in,functions |
R4977 |
T17402 |
T17401 |
pobj |
mammals,in |
R4978 |
T17403 |
T17374 |
punct |
.,includes |
R4979 |
T17405 |
T17406 |
det |
The,identities |
R4980 |
T17406 |
T17407 |
nsubj |
identities,remain |
R4981 |
T17408 |
T17406 |
cc |
and,identities |
R4982 |
T17409 |
T17406 |
conj |
roles,identities |
R4983 |
T17410 |
T17406 |
prep |
of,identities |
R4984 |
T17411 |
T17412 |
det |
these,genes |
R4985 |
T17412 |
T17410 |
pobj |
genes,of |
R4986 |
T17413 |
T17414 |
npadvmod |
Pygopus,redundant |
R4987 |
T17414 |
T17412 |
amod |
redundant,genes |
R4988 |
T17415 |
T17416 |
aux |
to,determined |
R4989 |
T17416 |
T17407 |
xcomp |
determined,remain |
R4990 |
T17417 |
T17416 |
auxpass |
be,determined |
R4991 |
T17418 |
T17407 |
punct |
.,remain |