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PMC:1635039 / 614-1141 JSONTXT 4 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T612 0-2 PRP denotes We
T613 3-10 VBD denotes deleted
T614 11-14 DT denotes the
T616 15-18 NN denotes TGF
T618 18-19 HYPH denotes -
T617 19-20 NN denotes β
T619 21-25 NN denotes type
T620 26-27 CD denotes I
T621 28-36 NN denotes receptor
T615 37-41 NN denotes Alk5
T622 42-54 RB denotes specifically
T623 55-57 IN denotes in
T624 58-61 DT denotes the
T626 62-67 NN denotes mouse
T627 68-74 JJ denotes neural
T629 75-80 NN denotes crest
T628 81-85 NN denotes cell
T625 86-93 NN denotes lineage
T630 93-94 . denotes .
T631 94-349 sentence denotes Failure in signaling via ALK5 leads to severe cardiovascular and pharyngeal defects, including inappropriate remodeling of pharyngeal arch arteries, abnormal aortic sac development, failure in pharyngeal organ migration and persistent truncus arteriosus.
T632 95-102 NN denotes Failure
T634 103-105 IN denotes in
T635 106-115 NN denotes signaling
T636 116-119 IN denotes via
T637 120-124 NN denotes ALK5
T633 125-130 VBZ denotes leads
T638 131-133 IN denotes to
T639 134-140 JJ denotes severe
T641 141-155 JJ denotes cardiovascular
T642 156-159 CC denotes and
T643 160-170 JJ denotes pharyngeal
T640 171-178 NNS denotes defects
T644 178-180 , denotes ,
T645 180-189 VBG denotes including
T646 190-203 JJ denotes inappropriate
T647 204-214 NN denotes remodeling
T648 215-217 IN denotes of
T649 218-228 JJ denotes pharyngeal
T651 229-233 NN denotes arch
T650 234-242 NNS denotes arteries
T652 242-244 , denotes ,
T653 244-252 JJ denotes abnormal
T655 253-259 JJ denotes aortic
T656 260-263 NN denotes sac
T654 264-275 NN denotes development
T657 275-277 , denotes ,
T658 277-284 NN denotes failure
T659 285-287 IN denotes in
T660 288-298 JJ denotes pharyngeal
T662 299-304 NN denotes organ
T661 305-314 NN denotes migration
T663 315-318 CC denotes and
T664 319-329 JJ denotes persistent
T666 330-337 NN denotes truncus
T665 338-348 NN denotes arteriosus
T667 348-349 . denotes .
T668 349-527 sentence denotes While ALK5 is not required for neural crest cell migration, our results demonstrate that it plays an important role in the survival of post-migratory cardiac neural crest cells.
T669 350-355 IN denotes While
T671 356-360 NN denotes ALK5
T672 361-363 VBZ denotes is
T673 364-367 RB denotes not
T670 368-376 VBN denotes required
T675 377-380 IN denotes for
T676 381-387 JJ denotes neural
T678 388-393 NN denotes crest
T677 394-398 NN denotes cell
T679 399-408 NN denotes migration
T680 408-410 , denotes ,
T681 410-413 PRP$ denotes our
T682 414-421 NNS denotes results
T674 422-433 VBP denotes demonstrate
T683 434-438 IN denotes that
T685 439-441 PRP denotes it
T684 442-447 VBZ denotes plays
T686 448-450 DT denotes an
T688 451-460 JJ denotes important
T687 461-465 NN denotes role
T689 466-468 IN denotes in
T690 469-472 DT denotes the
T691 473-481 NN denotes survival
T692 482-484 IN denotes of
T693 485-499 JJ denotes post-migratory
T695 500-507 JJ denotes cardiac
T697 508-514 JJ denotes neural
T696 515-520 NN denotes crest
T694 521-526 NNS denotes cells
T698 526-527 . denotes .
R100 T612 T613 nsubj We,deleted
R101 T614 T615 det the,Alk5
R102 T615 T613 dobj Alk5,deleted
R103 T616 T617 nmod TGF,β
R104 T617 T615 nmod β,Alk5
R105 T618 T617 punct -,β
R106 T619 T615 nmod type,Alk5
R107 T620 T619 nummod I,type
R108 T621 T615 compound receptor,Alk5
R109 T622 T613 advmod specifically,deleted
R110 T623 T613 prep in,deleted
R111 T624 T625 det the,lineage
R112 T625 T623 pobj lineage,in
R113 T626 T625 nmod mouse,lineage
R114 T627 T628 amod neural,cell
R115 T628 T625 compound cell,lineage
R116 T629 T628 compound crest,cell
R117 T630 T613 punct .,deleted
R118 T632 T633 nsubj Failure,leads
R119 T634 T632 prep in,Failure
R120 T635 T634 pobj signaling,in
R121 T636 T632 prep via,Failure
R122 T637 T636 pobj ALK5,via
R123 T638 T633 prep to,leads
R124 T639 T640 amod severe,defects
R125 T640 T638 pobj defects,to
R126 T641 T640 amod cardiovascular,defects
R127 T642 T641 cc and,cardiovascular
R128 T643 T641 conj pharyngeal,cardiovascular
R129 T644 T640 punct ", ",defects
R130 T645 T640 prep including,defects
R131 T646 T647 amod inappropriate,remodeling
R132 T647 T645 pobj remodeling,including
R133 T648 T647 prep of,remodeling
R134 T649 T650 amod pharyngeal,arteries
R135 T650 T648 pobj arteries,of
R136 T651 T650 compound arch,arteries
R137 T652 T647 punct ", ",remodeling
R138 T653 T654 amod abnormal,development
R139 T654 T647 appos development,remodeling
R140 T655 T656 amod aortic,sac
R141 T656 T654 compound sac,development
R142 T657 T647 punct ", ",remodeling
R143 T658 T647 appos failure,remodeling
R144 T659 T658 prep in,failure
R145 T660 T661 amod pharyngeal,migration
R146 T661 T659 pobj migration,in
R147 T662 T661 compound organ,migration
R148 T663 T661 cc and,migration
R149 T664 T665 amod persistent,arteriosus
R150 T665 T661 conj arteriosus,migration
R151 T666 T665 compound truncus,arteriosus
R152 T667 T633 punct .,leads
R153 T669 T670 mark While,required
R154 T670 T674 advcl required,demonstrate
R155 T671 T670 nsubjpass ALK5,required
R156 T672 T670 auxpass is,required
R157 T673 T670 neg not,required
R158 T675 T670 prep for,required
R159 T676 T677 amod neural,cell
R160 T677 T679 compound cell,migration
R161 T678 T677 compound crest,cell
R162 T679 T675 pobj migration,for
R163 T680 T674 punct ", ",demonstrate
R164 T681 T682 poss our,results
R165 T682 T674 nsubj results,demonstrate
R166 T683 T684 mark that,plays
R167 T684 T674 ccomp plays,demonstrate
R168 T685 T684 nsubj it,plays
R169 T686 T687 det an,role
R170 T687 T684 dobj role,plays
R171 T688 T687 amod important,role
R172 T689 T684 prep in,plays
R173 T690 T691 det the,survival
R174 T691 T689 pobj survival,in
R175 T692 T691 prep of,survival
R176 T693 T694 amod post-migratory,cells
R177 T694 T692 pobj cells,of
R178 T695 T696 amod cardiac,crest
R179 T696 T694 compound crest,cells
R180 T697 T696 amod neural,crest
R181 T698 T674 punct .,demonstrate