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PMC:1635039 / 606-1141 JSONTXT 4 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T610 0-7 NNS denotes Results
T611 7-102 sentence denotes We deleted the TGF-β type I receptor Alk5 specifically in the mouse neural crest cell lineage.
T612 8-10 PRP denotes We
T613 11-18 VBD denotes deleted
T614 19-22 DT denotes the
T616 23-26 NN denotes TGF
T618 26-27 HYPH denotes -
T617 27-28 NN denotes β
T619 29-33 NN denotes type
T620 34-35 CD denotes I
T621 36-44 NN denotes receptor
T615 45-49 NN denotes Alk5
T622 50-62 RB denotes specifically
T623 63-65 IN denotes in
T624 66-69 DT denotes the
T626 70-75 NN denotes mouse
T627 76-82 JJ denotes neural
T629 83-88 NN denotes crest
T628 89-93 NN denotes cell
T625 94-101 NN denotes lineage
T630 101-102 . denotes .
T631 102-357 sentence denotes Failure in signaling via ALK5 leads to severe cardiovascular and pharyngeal defects, including inappropriate remodeling of pharyngeal arch arteries, abnormal aortic sac development, failure in pharyngeal organ migration and persistent truncus arteriosus.
T632 103-110 NN denotes Failure
T634 111-113 IN denotes in
T635 114-123 NN denotes signaling
T636 124-127 IN denotes via
T637 128-132 NN denotes ALK5
T633 133-138 VBZ denotes leads
T638 139-141 IN denotes to
T639 142-148 JJ denotes severe
T641 149-163 JJ denotes cardiovascular
T642 164-167 CC denotes and
T643 168-178 JJ denotes pharyngeal
T640 179-186 NNS denotes defects
T644 186-188 , denotes ,
T645 188-197 VBG denotes including
T646 198-211 JJ denotes inappropriate
T647 212-222 NN denotes remodeling
T648 223-225 IN denotes of
T649 226-236 JJ denotes pharyngeal
T651 237-241 NN denotes arch
T650 242-250 NNS denotes arteries
T652 250-252 , denotes ,
T653 252-260 JJ denotes abnormal
T655 261-267 JJ denotes aortic
T656 268-271 NN denotes sac
T654 272-283 NN denotes development
T657 283-285 , denotes ,
T658 285-292 NN denotes failure
T659 293-295 IN denotes in
T660 296-306 JJ denotes pharyngeal
T662 307-312 NN denotes organ
T661 313-322 NN denotes migration
T663 323-326 CC denotes and
T664 327-337 JJ denotes persistent
T666 338-345 NN denotes truncus
T665 346-356 NN denotes arteriosus
T667 356-357 . denotes .
T668 357-535 sentence denotes While ALK5 is not required for neural crest cell migration, our results demonstrate that it plays an important role in the survival of post-migratory cardiac neural crest cells.
T669 358-363 IN denotes While
T671 364-368 NN denotes ALK5
T672 369-371 VBZ denotes is
T673 372-375 RB denotes not
T670 376-384 VBN denotes required
T675 385-388 IN denotes for
T676 389-395 JJ denotes neural
T678 396-401 NN denotes crest
T677 402-406 NN denotes cell
T679 407-416 NN denotes migration
T680 416-418 , denotes ,
T681 418-421 PRP$ denotes our
T682 422-429 NNS denotes results
T674 430-441 VBP denotes demonstrate
T683 442-446 IN denotes that
T685 447-449 PRP denotes it
T684 450-455 VBZ denotes plays
T686 456-458 DT denotes an
T688 459-468 JJ denotes important
T687 469-473 NN denotes role
T689 474-476 IN denotes in
T690 477-480 DT denotes the
T691 481-489 NN denotes survival
T692 490-492 IN denotes of
T693 493-507 JJ denotes post-migratory
T695 508-515 JJ denotes cardiac
T697 516-522 JJ denotes neural
T696 523-528 NN denotes crest
T694 529-534 NNS denotes cells
T698 534-535 . denotes .
R100 T612 T613 nsubj We,deleted
R101 T614 T615 det the,Alk5
R102 T615 T613 dobj Alk5,deleted
R103 T616 T617 nmod TGF,β
R104 T617 T615 nmod β,Alk5
R105 T618 T617 punct -,β
R106 T619 T615 nmod type,Alk5
R107 T620 T619 nummod I,type
R108 T621 T615 compound receptor,Alk5
R109 T622 T613 advmod specifically,deleted
R110 T623 T613 prep in,deleted
R111 T624 T625 det the,lineage
R112 T625 T623 pobj lineage,in
R113 T626 T625 nmod mouse,lineage
R114 T627 T628 amod neural,cell
R115 T628 T625 compound cell,lineage
R116 T629 T628 compound crest,cell
R117 T630 T613 punct .,deleted
R118 T632 T633 nsubj Failure,leads
R119 T634 T632 prep in,Failure
R120 T635 T634 pobj signaling,in
R121 T636 T632 prep via,Failure
R122 T637 T636 pobj ALK5,via
R123 T638 T633 prep to,leads
R124 T639 T640 amod severe,defects
R125 T640 T638 pobj defects,to
R126 T641 T640 amod cardiovascular,defects
R127 T642 T641 cc and,cardiovascular
R128 T643 T641 conj pharyngeal,cardiovascular
R129 T644 T640 punct ", ",defects
R130 T645 T640 prep including,defects
R131 T646 T647 amod inappropriate,remodeling
R132 T647 T645 pobj remodeling,including
R133 T648 T647 prep of,remodeling
R134 T649 T650 amod pharyngeal,arteries
R135 T650 T648 pobj arteries,of
R136 T651 T650 compound arch,arteries
R137 T652 T647 punct ", ",remodeling
R138 T653 T654 amod abnormal,development
R139 T654 T647 appos development,remodeling
R140 T655 T656 amod aortic,sac
R141 T656 T654 compound sac,development
R142 T657 T647 punct ", ",remodeling
R143 T658 T647 appos failure,remodeling
R144 T659 T658 prep in,failure
R145 T660 T661 amod pharyngeal,migration
R146 T661 T659 pobj migration,in
R147 T662 T661 compound organ,migration
R148 T663 T661 cc and,migration
R149 T664 T665 amod persistent,arteriosus
R150 T665 T661 conj arteriosus,migration
R151 T666 T665 compound truncus,arteriosus
R152 T667 T633 punct .,leads
R153 T669 T670 mark While,required
R154 T670 T674 advcl required,demonstrate
R155 T671 T670 nsubjpass ALK5,required
R156 T672 T670 auxpass is,required
R157 T673 T670 neg not,required
R158 T675 T670 prep for,required
R159 T676 T677 amod neural,cell
R160 T677 T679 compound cell,migration
R161 T678 T677 compound crest,cell
R162 T679 T675 pobj migration,for
R163 T680 T674 punct ", ",demonstrate
R164 T681 T682 poss our,results
R165 T682 T674 nsubj results,demonstrate
R166 T683 T684 mark that,plays
R167 T684 T674 ccomp plays,demonstrate
R168 T685 T684 nsubj it,plays
R169 T686 T687 det an,role
R170 T687 T684 dobj role,plays
R171 T688 T687 amod important,role
R172 T689 T684 prep in,plays
R173 T690 T691 det the,survival
R174 T691 T689 pobj survival,in
R175 T692 T691 prep of,survival
R176 T693 T694 amod post-migratory,cells
R177 T694 T692 pobj cells,of
R178 T695 T696 amod cardiac,crest
R179 T696 T694 compound crest,cells
R180 T697 T696 amod neural,crest
R181 T698 T674 punct .,demonstrate