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PMC:1626108 / 10077-12818 JSONTXT 4 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T10852 10-13 DT denotes The
T10853 14-16 NN denotes LD
T10855 17-19 IN denotes of
T10856 20-26 NN denotes RanBP2
T10854 27-36 VBZ denotes Interacts
T10857 37-41 IN denotes with
T10858 42-47 NN denotes Cox11
T10859 48-51 CC denotes and
T10860 52-55 NN denotes HKI
T10861 55-126 sentence denotes (A) Primary structure of RanBP2 and its structural/functional domains.
T10862 56-57 -LRB- denotes (
T10863 57-58 LS denotes A
T10865 58-59 -RRB- denotes )
T10866 60-67 JJ denotes Primary
T10864 68-77 NN denotes structure
T10867 78-80 IN denotes of
T10868 81-87 NN denotes RanBP2
T10869 88-91 CC denotes and
T10870 92-95 PRP$ denotes its
T10872 96-106 JJ denotes structural
T10874 106-107 HYPH denotes /
T10873 107-117 JJ denotes functional
T10871 118-125 NNS denotes domains
T10875 125-126 . denotes .
T10876 126-169 sentence denotes The N-terminal LD of RanBP2 is underlined.
T10877 127-130 DT denotes The
T10879 131-132 NN denotes N
T10881 132-133 HYPH denotes -
T10880 133-141 JJ denotes terminal
T10878 142-144 NN denotes LD
T10883 145-147 IN denotes of
T10884 148-154 NN denotes RanBP2
T10885 155-157 VBZ denotes is
T10882 158-168 VBN denotes underlined
T10886 168-169 . denotes .
T10887 169-219 sentence denotes (B) Sequence alignment of murine and yeast Cox11.
T10888 170-171 -LRB- denotes (
T10889 171-172 LS denotes B
T10891 172-173 -RRB- denotes )
T10892 174-182 NN denotes Sequence
T10890 183-192 NN denotes alignment
T10893 193-195 IN denotes of
T10894 196-202 JJ denotes murine
T10896 203-206 CC denotes and
T10897 207-212 NN denotes yeast
T10895 213-218 NN denotes Cox11
T10898 218-219 . denotes .
T10899 219-283 sentence denotes The yeast Cox11 C- and N-terminal domains are poorly conserved.
T10900 220-223 DT denotes The
T10902 224-229 NN denotes yeast
T10903 230-235 NN denotes Cox11
T10904 236-237 NN denotes C
T10906 237-238 HYPH denotes -
T10907 239-242 CC denotes and
T10908 243-244 NN denotes N
T10909 244-245 HYPH denotes -
T10905 245-253 JJ denotes terminal
T10901 254-261 NNS denotes domains
T10911 262-265 VBP denotes are
T10912 266-272 RB denotes poorly
T10910 273-282 VBN denotes conserved
T10913 282-283 . denotes .
T10914 283-383 sentence denotes Arrow and solid line denote the predicted mitochondrial cleavage site and membrane-spanning domain.
T10915 284-289 NN denotes Arrow
T10917 290-293 CC denotes and
T10918 294-299 JJ denotes solid
T10919 300-304 NN denotes line
T10916 305-311 VBP denotes denote
T10920 312-315 DT denotes the
T10922 316-325 VBN denotes predicted
T10923 326-339 JJ denotes mitochondrial
T10924 340-348 NN denotes cleavage
T10921 349-353 NN denotes site
T10925 354-357 CC denotes and
T10926 358-366 NN denotes membrane
T10928 366-367 HYPH denotes -
T10927 367-375 VBG denotes spanning
T10929 376-382 NN denotes domain
T10930 382-383 . denotes .
T10931 383-515 sentence denotes The dotted and dashed lines above the aligned sequences represent, respectively, Cox11-N and Cox11-C constructs shown in Figure 1C.
T10932 384-387 DT denotes The
T10934 388-394 JJ denotes dotted
T10935 395-398 CC denotes and
T10936 399-405 JJ denotes dashed
T10933 406-411 NNS denotes lines
T10938 412-417 IN denotes above
T10939 418-421 DT denotes the
T10941 422-429 JJ denotes aligned
T10940 430-439 NNS denotes sequences
T10937 440-449 VBP denotes represent
T10942 449-451 , denotes ,
T10943 451-463 RB denotes respectively
T10944 463-465 , denotes ,
T10945 465-470 NN denotes Cox11
T10947 470-471 HYPH denotes -
T10946 471-472 NN denotes N
T10949 473-476 CC denotes and
T10950 477-482 NN denotes Cox11
T10952 482-483 HYPH denotes -
T10951 483-484 NN denotes C
T10948 485-495 NNS denotes constructs
T10953 496-501 VBN denotes shown
T10954 502-504 IN denotes in
T10955 505-511 NN denotes Figure
T10956 512-514 NN denotes 1C
T10957 514-515 . denotes .
T10958 515-602 sentence denotes (C) Structure-function analysis of the interaction between the LD of RanBP2 and Cox11.
T10959 516-517 -LRB- denotes (
T10960 517-518 LS denotes C
T10962 518-519 -RRB- denotes )
T10963 520-529 NN denotes Structure
T10965 529-530 HYPH denotes -
T10964 530-538 NN denotes function
T10961 539-547 NN denotes analysis
T10966 548-550 IN denotes of
T10967 551-554 DT denotes the
T10968 555-566 NN denotes interaction
T10969 567-574 IN denotes between
T10970 575-578 DT denotes the
T10971 579-581 NN denotes LD
T10972 582-584 IN denotes of
T10973 585-591 NN denotes RanBP2
T10974 592-595 CC denotes and
T10975 596-601 NN denotes Cox11
T10976 601-602 . denotes .
T10977 602-729 sentence denotes Optimal interaction between the LD and Cox11 occurred in the presence of constructs comprising both the complete LD and Cox11.
T10978 603-610 JJ denotes Optimal
T10979 611-622 NN denotes interaction
T10981 623-630 IN denotes between
T10982 631-634 DT denotes the
T10983 635-637 NN denotes LD
T10984 638-641 CC denotes and
T10985 642-647 NN denotes Cox11
T10980 648-656 VBD denotes occurred
T10986 657-659 IN denotes in
T10987 660-663 DT denotes the
T10988 664-672 NN denotes presence
T10989 673-675 IN denotes of
T10990 676-686 NNS denotes constructs
T10991 687-697 VBG denotes comprising
T10992 698-702 CC denotes both
T10994 703-706 DT denotes the
T10995 707-715 JJ denotes complete
T10993 716-718 NN denotes LD
T10996 719-722 CC denotes and
T10997 723-728 NN denotes Cox11
T10998 728-729 . denotes .
T10999 729-981 sentence denotes Although removal of the cytosolic N-terminal (Cox11-C) significantly decreased the interaction with LD, the mitochondrial intermembrane domain of Cox11 (Cox11-C) together with the C-terminal half of LD (LD-C) retained most of the interaction activity.
T11000 730-738 IN denotes Although
T11002 739-746 NN denotes removal
T11003 747-749 IN denotes of
T11004 750-753 DT denotes the
T11006 754-763 JJ denotes cytosolic
T11005 764-765 NN denotes N
T11007 765-766 HYPH denotes -
T11008 766-774 JJ denotes terminal
T11009 775-776 -LRB- denotes (
T11010 776-781 NN denotes Cox11
T11012 781-782 HYPH denotes -
T11011 782-783 NN denotes C
T11013 783-784 -RRB- denotes )
T11014 785-798 RB denotes significantly
T11001 799-808 VBD denotes decreased
T11016 809-812 DT denotes the
T11017 813-824 NN denotes interaction
T11018 825-829 IN denotes with
T11019 830-832 NN denotes LD
T11020 832-834 , denotes ,
T11021 834-837 DT denotes the
T11023 838-851 JJ denotes mitochondrial
T11024 852-865 NN denotes intermembrane
T11022 866-872 NN denotes domain
T11025 873-875 IN denotes of
T11026 876-881 NN denotes Cox11
T11027 882-883 -LRB- denotes (
T11028 883-888 NN denotes Cox11
T11030 888-889 HYPH denotes -
T11029 889-890 NN denotes C
T11031 890-891 -RRB- denotes )
T11032 892-900 RB denotes together
T11033 901-905 IN denotes with
T11034 906-909 DT denotes the
T11036 910-911 NN denotes C
T11038 911-912 HYPH denotes -
T11037 912-920 JJ denotes terminal
T11035 921-925 NN denotes half
T11039 926-928 IN denotes of
T11040 929-931 NN denotes LD
T11041 932-933 -LRB- denotes (
T11042 933-935 NN denotes LD
T11044 935-936 HYPH denotes -
T11043 936-937 NN denotes C
T11045 937-938 -RRB- denotes )
T11015 939-947 VBD denotes retained
T11046 948-952 JJS denotes most
T11047 953-955 IN denotes of
T11048 956-959 DT denotes the
T11050 960-971 NN denotes interaction
T11049 972-980 NN denotes activity
T11051 980-981 . denotes .
T11052 981-1053 sentence denotes LD-N and LD-C ended and began with the leucine zipper domain of RanBP2.
T11053 982-984 NN denotes LD
T11055 984-985 HYPH denotes -
T11054 985-986 NN denotes N
T11057 987-990 CC denotes and
T11058 991-993 NN denotes LD
T11060 993-994 HYPH denotes -
T11059 994-995 NN denotes C
T11056 996-1001 VBD denotes ended
T11061 1002-1005 CC denotes and
T11062 1006-1011 VBD denotes began
T11063 1012-1016 IN denotes with
T11064 1017-1020 DT denotes the
T11066 1021-1028 NN denotes leucine
T11067 1029-1035 NN denotes zipper
T11065 1036-1042 NN denotes domain
T11068 1043-1045 IN denotes of
T11069 1046-1052 NN denotes RanBP2
T11070 1052-1053 . denotes .
T11071 1053-1165 sentence denotes White and black bars denote β-galactosidase activity and growth rates in selective growth medium, respectively.
T11072 1054-1059 JJ denotes White
T11074 1060-1063 CC denotes and
T11075 1064-1069 JJ denotes black
T11073 1070-1074 NNS denotes bars
T11076 1075-1081 VBP denotes denote
T11077 1082-1083 NN denotes β
T11079 1083-1084 HYPH denotes -
T11078 1084-1097 NN denotes galactosidase
T11080 1098-1106 NN denotes activity
T11081 1107-1110 CC denotes and
T11082 1111-1117 NN denotes growth
T11083 1118-1123 NNS denotes rates
T11084 1124-1126 IN denotes in
T11085 1127-1136 JJ denotes selective
T11087 1137-1143 NN denotes growth
T11086 1144-1150 NN denotes medium
T11088 1150-1152 , denotes ,
T11089 1152-1164 RB denotes respectively
T11090 1164-1165 . denotes .
T11091 1165-1211 sentence denotes Results shown represent the mean ± SD, n = 3.
T11092 1166-1173 NNS denotes Results
T11094 1174-1179 VBN denotes shown
T11093 1180-1189 VBP denotes represent
T11096 1190-1193 DT denotes the
T11098 1194-1198 NN denotes mean
T11099 1199-1200 SYM denotes ±
T11097 1201-1203 NN denotes SD
T11100 1203-1205 , denotes ,
T11101 1205-1206 NN denotes n
T11102 1207-1208 SYM denotes =
T11095 1209-1210 CD denotes 3
T11103 1210-1211 . denotes .
T11104 1211-1310 sentence denotes (D) GST pull-down assays with the LD of RanBP2 and its leucine zipper domain and retinal extracts.
T11105 1212-1213 -LRB- denotes (
T11106 1213-1214 LS denotes D
T11108 1214-1215 -RRB- denotes )
T11109 1216-1219 NN denotes GST
T11110 1220-1224 VB denotes pull
T11111 1224-1225 HYPH denotes -
T11112 1225-1229 RP denotes down
T11107 1230-1236 NNS denotes assays
T11113 1237-1241 IN denotes with
T11114 1242-1245 DT denotes the
T11115 1246-1248 NN denotes LD
T11116 1249-1251 IN denotes of
T11117 1252-1258 NN denotes RanBP2
T11118 1259-1262 CC denotes and
T11119 1263-1266 PRP$ denotes its
T11121 1267-1274 NN denotes leucine
T11122 1275-1281 NN denotes zipper
T11120 1282-1288 NN denotes domain
T11123 1289-1292 CC denotes and
T11124 1293-1300 JJ denotes retinal
T11125 1301-1309 NNS denotes extracts
T11126 1309-1310 . denotes .
T11127 1310-1436 sentence denotes The LD, but not the leucine zipper domain of RanBP2, associate with Cox11 (top panel, lane 1) and HKI (bottom panel, lane 1).
T11128 1311-1314 DT denotes The
T11129 1315-1317 NN denotes LD
T11131 1317-1319 , denotes ,
T11132 1319-1322 CC denotes but
T11133 1323-1326 RB denotes not
T11134 1327-1330 DT denotes the
T11136 1331-1338 NN denotes leucine
T11137 1339-1345 NN denotes zipper
T11135 1346-1352 NN denotes domain
T11138 1353-1355 IN denotes of
T11139 1356-1362 NN denotes RanBP2
T11140 1362-1364 , denotes ,
T11130 1364-1373 VBP denotes associate
T11141 1374-1378 IN denotes with
T11142 1379-1384 NN denotes Cox11
T11143 1385-1386 -LRB- denotes (
T11145 1386-1389 JJ denotes top
T11146 1390-1395 NN denotes panel
T11147 1395-1397 , denotes ,
T11144 1397-1401 NN denotes lane
T11148 1402-1403 CD denotes 1
T11149 1403-1404 -RRB- denotes )
T11150 1405-1408 CC denotes and
T11151 1409-1412 NN denotes HKI
T11152 1413-1414 -LRB- denotes (
T11154 1414-1420 JJ denotes bottom
T11155 1421-1426 NN denotes panel
T11156 1426-1428 , denotes ,
T11153 1428-1432 NN denotes lane
T11157 1433-1434 CD denotes 1
T11158 1434-1435 -RRB- denotes )
T11159 1435-1436 . denotes .
T11160 1436-1624 sentence denotes (E) Coimmunoprecipitation of RanBP2 with antibodies against its molecular partners shows that RanBP2 forms a complex in vivo with HKI (lanes 1 and 2), mHsp70 (lane 3), and Cox11 (lane 4).
T11161 1437-1438 -LRB- denotes (
T11162 1438-1439 LS denotes E
T11164 1439-1440 -RRB- denotes )
T11165 1441-1462 NN denotes Coimmunoprecipitation
T11166 1463-1465 IN denotes of
T11167 1466-1472 NN denotes RanBP2
T11168 1473-1477 IN denotes with
T11169 1478-1488 NNS denotes antibodies
T11170 1489-1496 IN denotes against
T11171 1497-1500 PRP$ denotes its
T11173 1501-1510 JJ denotes molecular
T11172 1511-1519 NNS denotes partners
T11163 1520-1525 VBZ denotes shows
T11174 1526-1530 IN denotes that
T11176 1531-1537 NN denotes RanBP2
T11175 1538-1543 VBZ denotes forms
T11177 1544-1545 DT denotes a
T11178 1546-1553 JJ denotes complex
T11179 1554-1556 FW denotes in
T11180 1557-1561 FW denotes vivo
T11181 1562-1566 IN denotes with
T11182 1567-1570 NN denotes HKI
T11183 1571-1572 -LRB- denotes (
T11185 1572-1577 NNS denotes lanes
T11184 1578-1579 CD denotes 1
T11186 1580-1583 CC denotes and
T11187 1584-1585 CD denotes 2
T11188 1585-1586 -RRB- denotes )
T11189 1586-1588 , denotes ,
T11190 1588-1594 NN denotes mHsp70
T11191 1595-1596 -LRB- denotes (
T11192 1596-1600 NN denotes lane
T11193 1601-1602 CD denotes 3
T11194 1602-1603 -RRB- denotes )
T11195 1603-1605 , denotes ,
T11196 1605-1608 CC denotes and
T11197 1609-1614 NN denotes Cox11
T11198 1615-1616 -LRB- denotes (
T11199 1616-1620 NN denotes lane
T11200 1621-1622 CD denotes 4
T11201 1622-1623 -RRB- denotes )
T11202 1623-1624 . denotes .
T11203 1624-1776 sentence denotes Lanes 5, 6, and 7 are control immunoprecipitation reactions with different antibodies against the RanBP2 domains, KBD, ZnF, and XAFXFG of nucleoporins.
T11204 1625-1630 NNS denotes Lanes
T11205 1631-1632 CD denotes 5
T11207 1632-1634 , denotes ,
T11208 1634-1635 CD denotes 6
T11209 1635-1637 , denotes ,
T11210 1637-1640 CC denotes and
T11211 1641-1642 CD denotes 7
T11206 1643-1646 VBP denotes are
T11212 1647-1654 NN denotes control
T11214 1655-1674 NN denotes immunoprecipitation
T11213 1675-1684 NNS denotes reactions
T11215 1685-1689 IN denotes with
T11216 1690-1699 JJ denotes different
T11217 1700-1710 NNS denotes antibodies
T11218 1711-1718 IN denotes against
T11219 1719-1722 DT denotes the
T11221 1723-1729 NN denotes RanBP2
T11220 1730-1737 NNS denotes domains
T11222 1737-1739 , denotes ,
T11223 1739-1742 NN denotes KBD
T11224 1742-1744 , denotes ,
T11225 1744-1747 NN denotes ZnF
T11226 1747-1749 , denotes ,
T11227 1749-1752 CC denotes and
T11228 1753-1759 NN denotes XAFXFG
T11229 1760-1762 IN denotes of
T11230 1763-1775 NNS denotes nucleoporins
T11231 1775-1776 . denotes .
T11232 1776-1876 sentence denotes (F) Reciprocal coimmunoprecipitation of HKI with antibodies against RanBP2 (used and shown in (E)).
T11233 1777-1778 -LRB- denotes (
T11234 1778-1779 LS denotes F
T11236 1779-1780 -RRB- denotes )
T11237 1781-1791 JJ denotes Reciprocal
T11235 1792-1813 NN denotes coimmunoprecipitation
T11238 1814-1816 IN denotes of
T11239 1817-1820 NN denotes HKI
T11240 1821-1825 IN denotes with
T11241 1826-1836 NNS denotes antibodies
T11242 1837-1844 IN denotes against
T11243 1845-1851 NN denotes RanBP2
T11244 1852-1853 -LRB- denotes (
T11245 1853-1857 VBN denotes used
T11246 1858-1861 CC denotes and
T11247 1862-1867 VBN denotes shown
T11248 1868-1870 IN denotes in
T11249 1871-1872 -LRB- denotes (
T11250 1872-1873 NN denotes E
T11251 1873-1874 -RRB- denotes )
T11252 1874-1875 -RRB- denotes )
T11253 1875-1876 . denotes .
T11254 1876-2153 sentence denotes (G) Reconstitution pull-down assays with purified LD and increasing concentrations of native (top panel), denatured (middle panel), and partially denatured (bottom panel) Cox11, respectively, in the absence and presence of denaturating agent, GnHCl and chaotropic agent, urea.
T11255 1877-1878 -LRB- denotes (
T11256 1878-1879 LS denotes G
T11258 1879-1880 -RRB- denotes )
T11259 1881-1895 NN denotes Reconstitution
T11260 1896-1900 VB denotes pull
T11261 1900-1901 HYPH denotes -
T11262 1901-1905 RP denotes down
T11257 1906-1912 NNS denotes assays
T11263 1913-1917 IN denotes with
T11264 1918-1926 VBN denotes purified
T11265 1927-1929 NN denotes LD
T11266 1930-1933 CC denotes and
T11267 1934-1944 VBG denotes increasing
T11268 1945-1959 NNS denotes concentrations
T11269 1960-1962 IN denotes of
T11270 1963-1969 JJ denotes native
T11272 1970-1971 -LRB- denotes (
T11274 1971-1974 JJ denotes top
T11273 1975-1980 NN denotes panel
T11275 1980-1981 -RRB- denotes )
T11276 1981-1983 , denotes ,
T11277 1983-1992 VBN denotes denatured
T11278 1993-1994 -LRB- denotes (
T11280 1994-2000 JJ denotes middle
T11279 2001-2006 NN denotes panel
T11281 2006-2007 -RRB- denotes )
T11282 2007-2009 , denotes ,
T11283 2009-2012 CC denotes and
T11284 2013-2022 RB denotes partially
T11285 2023-2032 VBN denotes denatured
T11286 2033-2034 -LRB- denotes (
T11288 2034-2040 JJ denotes bottom
T11287 2041-2046 NN denotes panel
T11289 2046-2047 -RRB- denotes )
T11271 2048-2053 NN denotes Cox11
T11290 2053-2055 , denotes ,
T11291 2055-2067 RB denotes respectively
T11292 2067-2069 , denotes ,
T11293 2069-2071 IN denotes in
T11294 2072-2075 DT denotes the
T11295 2076-2083 NN denotes absence
T11296 2084-2087 CC denotes and
T11297 2088-2096 NN denotes presence
T11298 2097-2099 IN denotes of
T11299 2100-2112 VBG denotes denaturating
T11300 2113-2118 NN denotes agent
T11301 2118-2120 , denotes ,
T11302 2120-2125 NN denotes GnHCl
T11303 2126-2129 CC denotes and
T11304 2130-2140 JJ denotes chaotropic
T11305 2141-2146 NN denotes agent
T11306 2146-2148 , denotes ,
T11307 2148-2152 NN denotes urea
T11308 2152-2153 . denotes .
T11309 2153-2260 sentence denotes Folding intermediates (lower panel) of Cox11 exhibit the highest binding activity toward the LD of RanBP2.
T11310 2154-2161 NN denotes Folding
T11311 2162-2175 NNS denotes intermediates
T11313 2176-2177 -LRB- denotes (
T11315 2177-2182 JJR denotes lower
T11314 2183-2188 NN denotes panel
T11316 2188-2189 -RRB- denotes )
T11317 2190-2192 IN denotes of
T11318 2193-2198 NN denotes Cox11
T11312 2199-2206 VBP denotes exhibit
T11319 2207-2210 DT denotes the
T11321 2211-2218 JJS denotes highest
T11322 2219-2226 NN denotes binding
T11320 2227-2235 NN denotes activity
T11323 2236-2242 IN denotes toward
T11324 2243-2246 DT denotes the
T11325 2247-2249 NN denotes LD
T11326 2250-2252 IN denotes of
T11327 2253-2259 NN denotes RanBP2
T11328 2259-2260 . denotes .
T11329 2260-2404 sentence denotes (H) Similar experiments as in (G) but in the presence of native Cox11 expressed in the absence (top panel) or presence (bottom panel) of CuSO4.
T11330 2261-2262 -LRB- denotes (
T11331 2262-2263 LS denotes H
T11333 2263-2264 -RRB- denotes )
T11334 2265-2272 JJ denotes Similar
T11332 2273-2284 NNS denotes experiments
T11335 2285-2287 IN denotes as
T11336 2288-2290 IN denotes in
T11337 2291-2292 -LRB- denotes (
T11338 2292-2293 NN denotes G
T11339 2293-2294 -RRB- denotes )
T11340 2295-2298 IN denotes but
T11341 2299-2301 IN denotes in
T11342 2302-2305 DT denotes the
T11343 2306-2314 NN denotes presence
T11344 2315-2317 IN denotes of
T11345 2318-2324 JJ denotes native
T11346 2325-2330 NN denotes Cox11
T11347 2331-2340 VBN denotes expressed
T11348 2341-2343 IN denotes in
T11349 2344-2347 DT denotes the
T11350 2348-2355 NN denotes absence
T11351 2356-2357 -LRB- denotes (
T11353 2357-2360 JJ denotes top
T11352 2361-2366 NN denotes panel
T11354 2366-2367 -RRB- denotes )
T11355 2368-2370 CC denotes or
T11356 2371-2379 NN denotes presence
T11357 2380-2381 -LRB- denotes (
T11359 2381-2387 JJ denotes bottom
T11358 2388-2393 NN denotes panel
T11360 2393-2394 -RRB- denotes )
T11361 2395-2397 IN denotes of
T11362 2398-2403 NN denotes CuSO4
T11363 2403-2404 . denotes .
T11364 2404-2498 sentence denotes The mature isoform of the metallochaperone has an increased affinity toward the LD of RanBP2.
T11365 2405-2408 DT denotes The
T11367 2409-2415 JJ denotes mature
T11366 2416-2423 NN denotes isoform
T11369 2424-2426 IN denotes of
T11370 2427-2430 DT denotes the
T11371 2431-2447 NN denotes metallochaperone
T11368 2448-2451 VBZ denotes has
T11372 2452-2454 DT denotes an
T11374 2455-2464 VBN denotes increased
T11373 2465-2473 NN denotes affinity
T11375 2474-2480 IN denotes toward
T11376 2481-2484 DT denotes the
T11377 2485-2487 NN denotes LD
T11378 2488-2490 IN denotes of
T11379 2491-2497 NN denotes RanBP2
T11380 2497-2498 . denotes .
T11381 2498-2741 sentence denotes LD, leucine-rich domain; LZ, leucine zipper domain; RBD1–4, Ran-binding domains 1–4; ZnF, zinc finger cluster domain; KBD, kinesin (KIF5B/KIF5C)-binding domain; CLD, cyclophilin-like domain; IR, internal repeat domain; CY, cyclophilin domain.
T11382 2499-2501 NN denotes LD
T11383 2501-2503 , denotes ,
T11384 2503-2510 NN denotes leucine
T11386 2510-2511 HYPH denotes -
T11385 2511-2515 JJ denotes rich
T11387 2516-2522 NN denotes domain
T11388 2522-2523 : denotes ;
T11389 2524-2526 NN denotes LZ
T11390 2526-2528 , denotes ,
T11391 2528-2535 NN denotes leucine
T11392 2536-2542 NN denotes zipper
T11393 2543-2549 NN denotes domain
T11394 2549-2550 : denotes ;
T11395 2551-2555 NN denotes RBD1
T11396 2555-2556 SYM denotes –
T11397 2556-2557 CD denotes 4
T11398 2557-2559 , denotes ,
T11399 2559-2562 NN denotes Ran
T11401 2562-2563 HYPH denotes -
T11400 2563-2570 NN denotes binding
T11402 2571-2578 NNS denotes domains
T11403 2579-2580 CD denotes 1
T11405 2580-2581 SYM denotes –
T11404 2581-2582 CD denotes 4
T11406 2582-2583 : denotes ;
T11407 2584-2587 NN denotes ZnF
T11408 2587-2589 , denotes ,
T11409 2589-2593 NN denotes zinc
T11410 2594-2600 NN denotes finger
T11412 2601-2608 NN denotes cluster
T11411 2609-2615 NN denotes domain
T11413 2615-2616 : denotes ;
T11414 2617-2620 NN denotes KBD
T11415 2620-2622 , denotes ,
T11416 2622-2629 NN denotes kinesin
T11418 2630-2631 -LRB- denotes (
T11419 2631-2636 NN denotes KIF5B
T11421 2636-2637 HYPH denotes /
T11420 2637-2642 NN denotes KIF5C
T11422 2642-2643 -RRB- denotes )
T11423 2643-2644 HYPH denotes -
T11417 2644-2651 NN denotes binding
T11424 2652-2658 NN denotes domain
T11425 2658-2659 : denotes ;
T11426 2660-2663 NN denotes CLD
T11427 2663-2665 , denotes ,
T11428 2665-2676 NN denotes cyclophilin
T11430 2676-2677 HYPH denotes -
T11429 2677-2681 JJ denotes like
T11431 2682-2688 NN denotes domain
T11432 2688-2689 : denotes ;
T11433 2690-2692 NN denotes IR
T11434 2692-2694 , denotes ,
T11435 2694-2702 JJ denotes internal
T11436 2703-2709 NN denotes repeat
T11437 2710-2716 NN denotes domain
T11438 2716-2717 : denotes ;
T11439 2718-2720 NN denotes CY
T11440 2720-2722 , denotes ,
T11441 2722-2733 NN denotes cyclophilin
T11442 2734-2740 NN denotes domain
T11443 2740-2741 . denotes .
R7150 T10852 T10853 det The,LD
R7151 T10853 T10854 nsubj LD,Interacts
R7152 T10855 T10853 prep of,LD
R7153 T10856 T10855 pobj RanBP2,of
R7154 T10857 T10854 prep with,Interacts
R7155 T10858 T10857 pobj Cox11,with
R7156 T10859 T10858 cc and,Cox11
R7157 T10860 T10858 conj HKI,Cox11
R7158 T10862 T10863 punct (,A
R7159 T10863 T10864 meta A,structure
R7160 T10865 T10863 punct ),A
R7161 T10866 T10864 amod Primary,structure
R7162 T10867 T10864 prep of,structure
R7163 T10868 T10867 pobj RanBP2,of
R7164 T10869 T10864 cc and,structure
R7165 T10870 T10871 poss its,domains
R7166 T10871 T10864 conj domains,structure
R7167 T10872 T10873 amod structural,functional
R7168 T10873 T10871 amod functional,domains
R7169 T10874 T10873 punct /,functional
R7170 T10875 T10871 punct .,domains
R7171 T10877 T10878 det The,LD
R7172 T10878 T10882 nsubjpass LD,underlined
R7173 T10879 T10880 npadvmod N,terminal
R7174 T10880 T10878 amod terminal,LD
R7175 T10881 T10880 punct -,terminal
R7176 T10883 T10878 prep of,LD
R7177 T10884 T10883 pobj RanBP2,of
R7178 T10885 T10882 auxpass is,underlined
R7179 T10886 T10882 punct .,underlined
R7180 T10888 T10889 punct (,B
R7181 T10889 T10890 meta B,alignment
R7182 T10891 T10889 punct ),B
R7183 T10892 T10890 compound Sequence,alignment
R7184 T10893 T10890 prep of,alignment
R7185 T10894 T10895 amod murine,Cox11
R7186 T10895 T10893 pobj Cox11,of
R7187 T10896 T10894 cc and,murine
R7188 T10897 T10894 conj yeast,murine
R7189 T10898 T10890 punct .,alignment
R7190 T10900 T10901 det The,domains
R7191 T10901 T10910 nsubjpass domains,conserved
R7192 T10902 T10901 nmod yeast,domains
R7193 T10903 T10901 nmod Cox11,domains
R7194 T10904 T10905 npadvmod C,terminal
R7195 T10905 T10901 amod terminal,domains
R7196 T10906 T10904 punct -,C
R7197 T10907 T10904 cc and,C
R7198 T10908 T10904 conj N,C
R7199 T10909 T10905 punct -,terminal
R7200 T10911 T10910 auxpass are,conserved
R7201 T10912 T10910 advmod poorly,conserved
R7202 T10913 T10910 punct .,conserved
R7203 T10915 T10916 nsubj Arrow,denote
R7204 T10917 T10915 cc and,Arrow
R7205 T10918 T10919 amod solid,line
R7206 T10919 T10915 conj line,Arrow
R7207 T10920 T10921 det the,site
R7208 T10921 T10916 dobj site,denote
R7209 T10922 T10921 amod predicted,site
R7210 T10923 T10924 amod mitochondrial,cleavage
R7211 T10924 T10921 compound cleavage,site
R7212 T10925 T10921 cc and,site
R7213 T10926 T10927 npadvmod membrane,spanning
R7214 T10927 T10929 amod spanning,domain
R7215 T10928 T10927 punct -,spanning
R7216 T10929 T10921 conj domain,site
R7217 T10930 T10916 punct .,denote
R7218 T10932 T10933 det The,lines
R7219 T10933 T10937 nsubj lines,represent
R7220 T10934 T10933 amod dotted,lines
R7221 T10935 T10934 cc and,dotted
R7222 T10936 T10934 conj dashed,dotted
R7223 T10938 T10933 prep above,lines
R7224 T10939 T10940 det the,sequences
R7225 T10940 T10938 pobj sequences,above
R7226 T10941 T10940 amod aligned,sequences
R7227 T10942 T10937 punct ", ",represent
R7228 T10943 T10937 advmod respectively,represent
R7229 T10944 T10937 punct ", ",represent
R7230 T10945 T10946 nmod Cox11,N
R7231 T10946 T10948 nmod N,constructs
R7232 T10947 T10946 punct -,N
R7233 T10948 T10937 dobj constructs,represent
R7234 T10949 T10946 cc and,N
R7235 T10950 T10951 compound Cox11,C
R7236 T10951 T10946 conj C,N
R7237 T10952 T10951 punct -,C
R7238 T10953 T10948 acl shown,constructs
R7239 T10954 T10953 prep in,shown
R7240 T10955 T10956 compound Figure,1C
R7241 T10956 T10954 pobj 1C,in
R7242 T10957 T10937 punct .,represent
R7243 T10959 T10960 punct (,C
R7244 T10960 T10961 meta C,analysis
R7245 T10962 T10960 punct ),C
R7246 T10963 T10964 compound Structure,function
R7247 T10964 T10961 compound function,analysis
R7248 T10965 T10964 punct -,function
R7249 T10966 T10961 prep of,analysis
R7250 T10967 T10968 det the,interaction
R7251 T10968 T10966 pobj interaction,of
R7252 T10969 T10968 prep between,interaction
R7253 T10970 T10971 det the,LD
R7254 T10971 T10969 pobj LD,between
R7255 T10972 T10971 prep of,LD
R7256 T10973 T10972 pobj RanBP2,of
R7257 T10974 T10971 cc and,LD
R7258 T10975 T10971 conj Cox11,LD
R7259 T10976 T10961 punct .,analysis
R7260 T10978 T10979 amod Optimal,interaction
R7261 T10979 T10980 nsubj interaction,occurred
R7262 T10981 T10979 prep between,interaction
R7263 T10982 T10983 det the,LD
R7264 T10983 T10981 pobj LD,between
R7265 T10984 T10983 cc and,LD
R7266 T10985 T10983 conj Cox11,LD
R7267 T10986 T10980 prep in,occurred
R7268 T10987 T10988 det the,presence
R7269 T10988 T10986 pobj presence,in
R7270 T10989 T10988 prep of,presence
R7271 T10990 T10989 pobj constructs,of
R7272 T10991 T10990 acl comprising,constructs
R7273 T10992 T10993 preconj both,LD
R7274 T10993 T10991 dobj LD,comprising
R7275 T10994 T10993 det the,LD
R7276 T10995 T10993 amod complete,LD
R7277 T10996 T10993 cc and,LD
R7278 T10997 T10993 conj Cox11,LD
R7279 T10998 T10980 punct .,occurred
R7280 T11000 T11001 mark Although,decreased
R7281 T11001 T11015 advcl decreased,retained
R7282 T11002 T11001 nsubj removal,decreased
R7283 T11003 T11002 prep of,removal
R7284 T11004 T11005 det the,N
R7285 T11005 T11003 pobj N,of
R7286 T11006 T11005 amod cytosolic,N
R7287 T11007 T11005 punct -,N
R7288 T11008 T11005 amod terminal,N
R7289 T11009 T11002 punct (,removal
R7290 T11010 T11011 compound Cox11,C
R7291 T11011 T11002 appos C,removal
R7292 T11012 T11011 punct -,C
R7293 T11013 T11001 punct ),decreased
R7294 T11014 T11001 advmod significantly,decreased
R7295 T11016 T11017 det the,interaction
R7296 T11017 T11001 dobj interaction,decreased
R7297 T11018 T11017 prep with,interaction
R7298 T11019 T11018 pobj LD,with
R7299 T11020 T11015 punct ", ",retained
R7300 T11021 T11022 det the,domain
R7301 T11022 T11015 nsubj domain,retained
R7302 T11023 T11022 amod mitochondrial,domain
R7303 T11024 T11022 compound intermembrane,domain
R7304 T11025 T11022 prep of,domain
R7305 T11026 T11025 pobj Cox11,of
R7306 T11027 T11022 punct (,domain
R7307 T11028 T11029 compound Cox11,C
R7308 T11029 T11022 appos C,domain
R7309 T11030 T11029 punct -,C
R7310 T11031 T11022 punct ),domain
R7311 T11032 T11022 advmod together,domain
R7312 T11033 T11032 prep with,together
R7313 T11034 T11035 det the,half
R7314 T11035 T11033 pobj half,with
R7315 T11036 T11037 npadvmod C,terminal
R7316 T11037 T11035 amod terminal,half
R7317 T11038 T11037 punct -,terminal
R7318 T11039 T11035 prep of,half
R7319 T11040 T11039 pobj LD,of
R7320 T11041 T11035 punct (,half
R7321 T11042 T11043 compound LD,C
R7322 T11043 T11035 appos C,half
R7323 T11044 T11043 punct -,C
R7324 T11045 T11015 punct ),retained
R7325 T11046 T11015 dobj most,retained
R7326 T11047 T11046 prep of,most
R7327 T11048 T11049 det the,activity
R7328 T11049 T11047 pobj activity,of
R7329 T11050 T11049 compound interaction,activity
R7330 T11051 T11015 punct .,retained
R7331 T11053 T11054 compound LD,N
R7332 T11054 T11056 nsubj N,ended
R7333 T11055 T11054 punct -,N
R7334 T11057 T11054 cc and,N
R7335 T11058 T11059 compound LD,C
R7336 T11059 T11054 conj C,N
R7337 T11060 T11059 punct -,C
R7338 T11061 T11056 cc and,ended
R7339 T11062 T11056 conj began,ended
R7340 T11063 T11062 prep with,began
R7341 T11064 T11065 det the,domain
R7342 T11065 T11063 pobj domain,with
R7343 T11066 T11067 compound leucine,zipper
R7344 T11067 T11065 compound zipper,domain
R7345 T11068 T11065 prep of,domain
R7346 T11069 T11068 pobj RanBP2,of
R7347 T11070 T11056 punct .,ended
R7348 T11072 T11073 amod White,bars
R7349 T11073 T11076 nsubj bars,denote
R7350 T11074 T11072 cc and,White
R7351 T11075 T11072 conj black,White
R7352 T11077 T11078 compound β,galactosidase
R7353 T11078 T11080 compound galactosidase,activity
R7354 T11079 T11078 punct -,galactosidase
R7355 T11080 T11076 dobj activity,denote
R7356 T11081 T11080 cc and,activity
R7357 T11082 T11083 compound growth,rates
R7358 T11083 T11080 conj rates,activity
R7359 T11084 T11083 prep in,rates
R7360 T11085 T11086 amod selective,medium
R7361 T11086 T11084 pobj medium,in
R7362 T11087 T11086 compound growth,medium
R7363 T11088 T11076 punct ", ",denote
R7364 T11089 T11076 advmod respectively,denote
R7365 T11090 T11076 punct .,denote
R7366 T11092 T11093 nsubj Results,represent
R7367 T11093 T11095 ccomp represent,3
R7368 T11094 T11092 acl shown,Results
R7369 T11096 T11097 det the,SD
R7370 T11097 T11093 dobj SD,represent
R7371 T11098 T11097 nmod mean,SD
R7372 T11099 T11097 punct ±,SD
R7373 T11100 T11095 punct ", ",3
R7374 T11101 T11095 nsubj n,3
R7375 T11102 T11095 punct =,3
R7376 T11103 T11095 punct .,3
R7377 T11105 T11106 punct (,D
R7378 T11106 T11107 meta D,assays
R7379 T11108 T11106 punct ),D
R7380 T11109 T11107 nmod GST,assays
R7381 T11110 T11107 amod pull,assays
R7382 T11111 T11110 punct -,pull
R7383 T11112 T11110 prt down,pull
R7384 T11113 T11107 prep with,assays
R7385 T11114 T11115 det the,LD
R7386 T11115 T11113 pobj LD,with
R7387 T11116 T11115 prep of,LD
R7388 T11117 T11116 pobj RanBP2,of
R7389 T11118 T11115 cc and,LD
R7390 T11119 T11120 poss its,domain
R7391 T11120 T11115 conj domain,LD
R7392 T11121 T11122 compound leucine,zipper
R7393 T11122 T11120 compound zipper,domain
R7394 T11123 T11120 cc and,domain
R7395 T11124 T11125 amod retinal,extracts
R7396 T11125 T11120 conj extracts,domain
R7397 T11126 T11107 punct .,assays
R7398 T11128 T11129 det The,LD
R7399 T11129 T11130 nsubj LD,associate
R7400 T11131 T11129 punct ", ",LD
R7401 T11132 T11129 cc but,LD
R7402 T11133 T11132 neg not,but
R7403 T11134 T11135 det the,domain
R7404 T11135 T11129 conj domain,LD
R7405 T11136 T11137 compound leucine,zipper
R7406 T11137 T11135 compound zipper,domain
R7407 T11138 T11129 prep of,LD
R7408 T11139 T11138 pobj RanBP2,of
R7409 T11140 T11130 punct ", ",associate
R7410 T11141 T11130 prep with,associate
R7411 T11142 T11141 pobj Cox11,with
R7412 T11143 T11144 punct (,lane
R7413 T11144 T11142 parataxis lane,Cox11
R7414 T11145 T11146 amod top,panel
R7415 T11146 T11144 dep panel,lane
R7416 T11147 T11144 punct ", ",lane
R7417 T11148 T11144 nummod 1,lane
R7418 T11149 T11144 punct ),lane
R7419 T11150 T11142 cc and,Cox11
R7420 T11151 T11142 conj HKI,Cox11
R7421 T11152 T11153 punct (,lane
R7422 T11153 T11151 parataxis lane,HKI
R7423 T11154 T11155 amod bottom,panel
R7424 T11155 T11153 dep panel,lane
R7425 T11156 T11153 punct ", ",lane
R7426 T11157 T11153 nummod 1,lane
R7427 T11158 T11153 punct ),lane
R7428 T11159 T11130 punct .,associate
R7429 T11161 T11162 punct (,E
R7430 T11162 T11163 meta E,shows
R7431 T11164 T11162 punct ),E
R7432 T11165 T11163 nsubj Coimmunoprecipitation,shows
R7433 T11166 T11165 prep of,Coimmunoprecipitation
R7434 T11167 T11166 pobj RanBP2,of
R7435 T11168 T11165 prep with,Coimmunoprecipitation
R7436 T11169 T11168 pobj antibodies,with
R7437 T11170 T11169 prep against,antibodies
R7438 T11171 T11172 poss its,partners
R7439 T11172 T11170 pobj partners,against
R7440 T11173 T11172 amod molecular,partners
R7441 T11174 T11175 mark that,forms
R7442 T11175 T11163 ccomp forms,shows
R7443 T11176 T11175 nsubj RanBP2,forms
R7444 T11177 T11178 det a,complex
R7445 T11178 T11175 dobj complex,forms
R7446 T11179 T11180 advmod in,vivo
R7447 T11180 T11175 advmod vivo,forms
R7448 T11181 T11175 prep with,forms
R7449 T11182 T11181 pobj HKI,with
R7450 T11183 T11184 punct (,1
R7451 T11184 T11182 parataxis 1,HKI
R7452 T11185 T11184 nmod lanes,1
R7453 T11186 T11184 cc and,1
R7454 T11187 T11184 conj 2,1
R7455 T11188 T11184 punct ),1
R7456 T11189 T11182 punct ", ",HKI
R7457 T11190 T11182 conj mHsp70,HKI
R7458 T11191 T11192 punct (,lane
R7459 T11192 T11190 parataxis lane,mHsp70
R7460 T11193 T11192 nummod 3,lane
R7461 T11194 T11192 punct ),lane
R7462 T11195 T11190 punct ", ",mHsp70
R7463 T11196 T11190 cc and,mHsp70
R7464 T11197 T11190 conj Cox11,mHsp70
R7465 T11198 T11199 punct (,lane
R7466 T11199 T11197 parataxis lane,Cox11
R7467 T11200 T11199 nummod 4,lane
R7468 T11201 T11199 punct ),lane
R7469 T11202 T11163 punct .,shows
R7470 T11204 T11205 nmod Lanes,5
R7471 T11205 T11206 nsubj 5,are
R7472 T11207 T11205 punct ", ",5
R7473 T11208 T11205 conj 6,5
R7474 T11209 T11208 punct ", ",6
R7475 T11210 T11208 cc and,6
R7476 T11211 T11208 conj 7,6
R7477 T11212 T11213 compound control,reactions
R7478 T11213 T11206 attr reactions,are
R7479 T11214 T11213 compound immunoprecipitation,reactions
R7480 T11215 T11213 prep with,reactions
R7481 T11216 T11217 amod different,antibodies
R7482 T11217 T11215 pobj antibodies,with
R7483 T11218 T11217 prep against,antibodies
R7484 T11219 T11220 det the,domains
R7485 T11220 T11218 pobj domains,against
R7486 T11221 T11220 compound RanBP2,domains
R7487 T11222 T11220 punct ", ",domains
R7488 T11223 T11220 appos KBD,domains
R7489 T11224 T11223 punct ", ",KBD
R7490 T11225 T11223 conj ZnF,KBD
R7491 T11226 T11225 punct ", ",ZnF
R7492 T11227 T11225 cc and,ZnF
R7493 T11228 T11225 conj XAFXFG,ZnF
R7494 T11229 T11220 prep of,domains
R7495 T11230 T11229 pobj nucleoporins,of
R7496 T11231 T11206 punct .,are
R7497 T11233 T11234 punct (,F
R7498 T11234 T11235 meta F,coimmunoprecipitation
R7499 T11236 T11234 punct ),F
R7500 T11237 T11235 amod Reciprocal,coimmunoprecipitation
R7501 T11238 T11235 prep of,coimmunoprecipitation
R7502 T11239 T11238 pobj HKI,of
R7503 T11240 T11235 prep with,coimmunoprecipitation
R7504 T11241 T11240 pobj antibodies,with
R7505 T11242 T11241 prep against,antibodies
R7506 T11243 T11242 pobj RanBP2,against
R7507 T11244 T11241 punct (,antibodies
R7508 T11245 T11241 acl used,antibodies
R7509 T11246 T11245 cc and,used
R7510 T11247 T11245 conj shown,used
R7511 T11248 T11247 prep in,shown
R7512 T11249 T11248 punct (,in
R7513 T11250 T11248 pobj E,in
R7514 T11251 T11235 punct ),coimmunoprecipitation
R7515 T11252 T11235 punct ),coimmunoprecipitation
R7516 T11253 T11235 punct .,coimmunoprecipitation
R7517 T11255 T11256 punct (,G
R7518 T11256 T11257 meta G,assays
R7519 T11258 T11256 punct ),G
R7520 T11259 T11257 nmod Reconstitution,assays
R7521 T11260 T11257 amod pull,assays
R7522 T11261 T11260 punct -,pull
R7523 T11262 T11260 prt down,pull
R7524 T11263 T11257 prep with,assays
R7525 T11264 T11265 amod purified,LD
R7526 T11265 T11263 pobj LD,with
R7527 T11266 T11265 cc and,LD
R7528 T11267 T11268 amod increasing,concentrations
R7529 T11268 T11265 conj concentrations,LD
R7530 T11269 T11268 prep of,concentrations
R7531 T11270 T11271 amod native,Cox11
R7532 T11271 T11269 pobj Cox11,of
R7533 T11272 T11273 punct (,panel
R7534 T11273 T11270 parataxis panel,native
R7535 T11274 T11273 amod top,panel
R7536 T11275 T11273 punct ),panel
R7537 T11276 T11270 punct ", ",native
R7538 T11277 T11270 conj denatured,native
R7539 T11278 T11279 punct (,panel
R7540 T11279 T11277 parataxis panel,denatured
R7541 T11280 T11279 amod middle,panel
R7542 T11281 T11279 punct ),panel
R7543 T11282 T11277 punct ", ",denatured
R7544 T11283 T11277 cc and,denatured
R7545 T11284 T11285 advmod partially,denatured
R7546 T11285 T11277 conj denatured,denatured
R7547 T11286 T11287 punct (,panel
R7548 T11287 T11285 parataxis panel,denatured
R7549 T11288 T11287 amod bottom,panel
R7550 T11289 T11287 punct ),panel
R7551 T11290 T11268 punct ", ",concentrations
R7552 T11291 T11268 advmod respectively,concentrations
R7553 T11292 T11257 punct ", ",assays
R7554 T11293 T11257 prep in,assays
R7555 T11294 T11295 det the,absence
R7556 T11295 T11293 pobj absence,in
R7557 T11296 T11295 cc and,absence
R7558 T11297 T11295 conj presence,absence
R7559 T11298 T11295 prep of,absence
R7560 T11299 T11300 amod denaturating,agent
R7561 T11300 T11298 pobj agent,of
R7562 T11301 T11300 punct ", ",agent
R7563 T11302 T11300 appos GnHCl,agent
R7564 T11303 T11300 cc and,agent
R7565 T11304 T11305 amod chaotropic,agent
R7566 T11305 T11300 conj agent,agent
R7567 T11306 T11305 punct ", ",agent
R7568 T11307 T11305 appos urea,agent
R7569 T11308 T11257 punct .,assays
R7570 T11310 T11311 compound Folding,intermediates
R7571 T11311 T11312 nsubj intermediates,exhibit
R7572 T11313 T11314 punct (,panel
R7573 T11314 T11311 parataxis panel,intermediates
R7574 T11315 T11314 amod lower,panel
R7575 T11316 T11314 punct ),panel
R7576 T11317 T11311 prep of,intermediates
R7577 T11318 T11317 pobj Cox11,of
R7578 T11319 T11320 det the,activity
R7579 T11320 T11312 dobj activity,exhibit
R7580 T11321 T11320 amod highest,activity
R7581 T11322 T11320 compound binding,activity
R7582 T11323 T11320 prep toward,activity
R7583 T11324 T11325 det the,LD
R7584 T11325 T11323 pobj LD,toward
R7585 T11326 T11325 prep of,LD
R7586 T11327 T11326 pobj RanBP2,of
R7587 T11328 T11312 punct .,exhibit
R7588 T11330 T11331 punct (,H
R7589 T11331 T11332 meta H,experiments
R7590 T11333 T11331 punct ),H
R7591 T11334 T11332 amod Similar,experiments
R7592 T11335 T11332 prep as,experiments
R7593 T11336 T11335 prep in,as
R7594 T11337 T11336 punct (,in
R7595 T11338 T11336 pobj G,in
R7596 T11339 T11332 punct ),experiments
R7597 T11340 T11332 prep but,experiments
R7598 T11341 T11340 prep in,but
R7599 T11342 T11343 det the,presence
R7600 T11343 T11341 pobj presence,in
R7601 T11344 T11343 prep of,presence
R7602 T11345 T11346 amod native,Cox11
R7603 T11346 T11344 pobj Cox11,of
R7604 T11347 T11346 acl expressed,Cox11
R7605 T11348 T11347 prep in,expressed
R7606 T11349 T11350 det the,absence
R7607 T11350 T11348 pobj absence,in
R7608 T11351 T11352 punct (,panel
R7609 T11352 T11350 parataxis panel,absence
R7610 T11353 T11352 amod top,panel
R7611 T11354 T11352 punct ),panel
R7612 T11355 T11350 cc or,absence
R7613 T11356 T11350 conj presence,absence
R7614 T11357 T11358 punct (,panel
R7615 T11358 T11356 parataxis panel,presence
R7616 T11359 T11358 amod bottom,panel
R7617 T11360 T11358 punct ),panel
R7618 T11361 T11350 prep of,absence
R7619 T11362 T11361 pobj CuSO4,of
R7620 T11363 T11332 punct .,experiments
R7621 T11365 T11366 det The,isoform
R7622 T11366 T11368 nsubj isoform,has
R7623 T11367 T11366 amod mature,isoform
R7624 T11369 T11366 prep of,isoform
R7625 T11370 T11371 det the,metallochaperone
R7626 T11371 T11369 pobj metallochaperone,of
R7627 T11372 T11373 det an,affinity
R7628 T11373 T11368 dobj affinity,has
R7629 T11374 T11373 amod increased,affinity
R7630 T11375 T11373 prep toward,affinity
R7631 T11376 T11377 det the,LD
R7632 T11377 T11375 pobj LD,toward
R7633 T11378 T11377 prep of,LD
R7634 T11379 T11378 pobj RanBP2,of
R7635 T11380 T11368 punct .,has
R7636 T11383 T11382 punct ", ",LD
R7637 T11384 T11385 npadvmod leucine,rich
R7638 T11385 T11387 amod rich,domain
R7639 T11386 T11385 punct -,rich
R7640 T11387 T11382 appos domain,LD
R7641 T11388 T11382 punct ;,LD
R7642 T11389 T11382 appos LZ,LD
R7643 T11390 T11389 punct ", ",LZ
R7644 T11391 T11392 compound leucine,zipper
R7645 T11392 T11393 compound zipper,domain
R7646 T11393 T11389 appos domain,LZ
R7647 T11394 T11382 punct ;,LD
R7648 T11395 T11382 appos RBD1,LD
R7649 T11396 T11397 punct –,4
R7650 T11397 T11395 prep 4,RBD1
R7651 T11398 T11395 punct ", ",RBD1
R7652 T11399 T11400 compound Ran,binding
R7653 T11400 T11402 compound binding,domains
R7654 T11401 T11400 punct -,binding
R7655 T11402 T11395 appos domains,RBD1
R7656 T11403 T11404 quantmod 1,4
R7657 T11404 T11402 npadvmod 4,domains
R7658 T11405 T11404 punct –,4
R7659 T11406 T11382 punct ;,LD
R7660 T11407 T11382 appos ZnF,LD
R7661 T11408 T11407 punct ", ",ZnF
R7662 T11409 T11410 compound zinc,finger
R7663 T11410 T11411 compound finger,domain
R7664 T11411 T11407 appos domain,ZnF
R7665 T11412 T11411 compound cluster,domain
R7666 T11413 T11382 punct ;,LD
R7667 T11414 T11382 appos KBD,LD
R7668 T11415 T11414 punct ", ",KBD
R7669 T11416 T11417 nmod kinesin,binding
R7670 T11417 T11424 compound binding,domain
R7671 T11418 T11416 punct (,kinesin
R7672 T11419 T11420 compound KIF5B,KIF5C
R7673 T11420 T11416 appos KIF5C,kinesin
R7674 T11421 T11420 punct /,KIF5C
R7675 T11422 T11417 punct ),binding
R7676 T11423 T11417 punct -,binding
R7677 T11424 T11414 appos domain,KBD
R7678 T11425 T11382 punct ;,LD
R7679 T11426 T11382 appos CLD,LD
R7680 T11427 T11426 punct ", ",CLD
R7681 T11428 T11429 npadvmod cyclophilin,like
R7682 T11429 T11431 amod like,domain
R7683 T11430 T11429 punct -,like
R7684 T11431 T11426 appos domain,CLD
R7685 T11432 T11382 punct ;,LD
R7686 T11433 T11382 appos IR,LD
R7687 T11434 T11433 punct ", ",IR
R7688 T11435 T11436 amod internal,repeat
R7689 T11436 T11437 compound repeat,domain
R7690 T11437 T11433 appos domain,IR
R7691 T11438 T11382 punct ;,LD
R7692 T11439 T11382 appos CY,LD
R7693 T11440 T11439 punct ", ",CY
R7694 T11441 T11442 compound cyclophilin,domain
R7695 T11442 T11439 appos domain,CY
R7696 T11443 T11382 punct .,LD