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PMC:1617083 / 5568-6565 JSONTXT 5 Projects

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Id Subject Object Predicate Lexical cue
T3569 0-1 NN denotes A
T3568 0-2 sentence denotes A
T3571 2-7 NN denotes panel
T3570 2-191 sentence denotes panel of chromosome substitution strains (CSS) was generated [11] by a "marker-assisted" breeding program where the progeny of a B6 × A/J cross were successively backcrossed to the B6 mice.
T3573 8-10 IN denotes of
T3574 11-21 NN denotes chromosome
T3576 22-34 NN denotes substitution
T3575 35-42 NNS denotes strains
T3577 43-44 -LRB- denotes (
T3578 44-47 NNS denotes CSS
T3579 47-48 -RRB- denotes )
T3580 49-52 VBD denotes was
T3572 53-62 VBN denotes generated
T3581 63-64 -LRB- denotes [
T3582 64-66 CD denotes 11
T3583 66-67 -RRB- denotes ]
T3584 68-70 IN denotes by
T3585 71-72 DT denotes a
T3587 73-74 `` denotes "
T3588 74-80 NN denotes marker
T3590 80-81 HYPH denotes -
T3589 81-89 VBN denotes assisted
T3591 89-90 '' denotes "
T3592 91-99 NN denotes breeding
T3586 100-107 NN denotes program
T3593 108-113 WRB denotes where
T3595 114-117 DT denotes the
T3596 118-125 NN denotes progeny
T3597 126-128 IN denotes of
T3598 129-130 DT denotes a
T3600 131-133 NN denotes B6
T3601 134-135 SYM denotes ×
T3602 136-137 NN denotes A
T3604 137-138 HYPH denotes /
T3603 138-139 NN denotes J
T3599 140-145 NN denotes cross
T3605 146-150 VBD denotes were
T3606 151-163 RB denotes successively
T3594 164-175 VBN denotes backcrossed
T3607 176-178 IN denotes to
T3608 179-182 DT denotes the
T3610 183-185 NN denotes B6
T3609 186-190 NNS denotes mice
T3611 190-191 . denotes .
T3612 191-300 sentence denotes Genetic markers were used to identify homozygosity in the background (B6) and the individual A/J chromosome.
T3613 192-199 JJ denotes Genetic
T3614 200-207 NNS denotes markers
T3616 208-212 VBD denotes were
T3615 213-217 VBN denotes used
T3617 218-220 TO denotes to
T3618 221-229 VB denotes identify
T3619 230-242 NN denotes homozygosity
T3620 243-245 IN denotes in
T3621 246-249 DT denotes the
T3623 250-260 NN denotes background
T3624 261-262 -LRB- denotes (
T3622 262-264 NN denotes B6
T3625 264-265 -RRB- denotes )
T3626 266-269 CC denotes and
T3627 270-273 DT denotes the
T3629 274-284 JJ denotes individual
T3630 285-286 NN denotes A
T3631 286-287 HYPH denotes /
T3628 287-288 NN denotes J
T3632 289-299 NN denotes chromosome
T3633 299-300 . denotes .
T3634 300-368 sentence denotes These strains have one chromosome from A/J mice in a B6 background.
T3635 301-306 DT denotes These
T3636 307-314 NNS denotes strains
T3637 315-319 VBP denotes have
T3638 320-323 CD denotes one
T3639 324-334 NN denotes chromosome
T3640 335-339 IN denotes from
T3641 340-341 NN denotes A
T3643 341-342 HYPH denotes /
T3642 342-343 NN denotes J
T3644 344-348 NNS denotes mice
T3645 349-351 IN denotes in
T3646 352-353 DT denotes a
T3648 354-356 NN denotes B6
T3647 357-367 NN denotes background
T3649 367-368 . denotes .
T3650 368-491 sentence denotes This allows the identification of a trait in one or more CSS and implies that at least one QTL resides on this chromosome.
T3651 369-373 DT denotes This
T3652 374-380 VBZ denotes allows
T3653 381-384 DT denotes the
T3654 385-399 NN denotes identification
T3655 400-402 IN denotes of
T3656 403-404 DT denotes a
T3657 405-410 NN denotes trait
T3658 411-413 IN denotes in
T3659 414-417 CD denotes one
T3661 418-420 CC denotes or
T3662 421-425 JJR denotes more
T3660 426-429 NN denotes CSS
T3663 430-433 CC denotes and
T3664 434-441 VBZ denotes implies
T3665 442-446 IN denotes that
T3667 447-449 RB denotes at
T3669 450-455 RBS denotes least
T3668 456-459 CD denotes one
T3670 460-463 NN denotes QTL
T3666 464-471 VBZ denotes resides
T3671 472-474 IN denotes on
T3672 475-479 DT denotes this
T3673 480-490 NN denotes chromosome
T3674 490-491 . denotes .
T3675 491-580 sentence denotes Use of this panel requires fewer mice to determine the QTL than does a genome-wide scan.
T3676 492-495 NN denotes Use
T3678 496-498 IN denotes of
T3679 499-503 DT denotes this
T3680 504-509 NN denotes panel
T3677 510-518 VBZ denotes requires
T3681 519-524 JJR denotes fewer
T3682 525-529 NNS denotes mice
T3683 530-532 TO denotes to
T3684 533-542 VB denotes determine
T3685 543-546 DT denotes the
T3686 547-550 NN denotes QTL
T3687 551-555 IN denotes than
T3688 556-560 VBZ denotes does
T3689 561-562 DT denotes a
T3691 563-569 NN denotes genome
T3693 569-570 HYPH denotes -
T3692 570-574 JJ denotes wide
T3690 575-579 NN denotes scan
T3694 579-580 . denotes .
T3695 580-664 sentence denotes Another advantage is the ability for detection of QTL in the presence of other QTL.
T3696 581-588 DT denotes Another
T3697 589-598 NN denotes advantage
T3698 599-601 VBZ denotes is
T3699 602-605 DT denotes the
T3700 606-613 NN denotes ability
T3701 614-617 IN denotes for
T3702 618-627 NN denotes detection
T3703 628-630 IN denotes of
T3704 631-634 NNS denotes QTL
T3705 635-637 IN denotes in
T3706 638-641 DT denotes the
T3707 642-650 NN denotes presence
T3708 651-653 IN denotes of
T3709 654-659 JJ denotes other
T3710 660-663 NN denotes QTL
T3711 663-664 . denotes .
T3712 664-740 sentence denotes In addition, initial screens with the CSS simplify the fine-mapping of QTL.
T3713 665-667 IN denotes In
T3715 668-676 NN denotes addition
T3716 676-678 , denotes ,
T3717 678-685 JJ denotes initial
T3718 686-693 NNS denotes screens
T3719 694-698 IN denotes with
T3720 699-702 DT denotes the
T3721 703-706 NN denotes CSS
T3714 707-715 VBP denotes simplify
T3722 716-719 DT denotes the
T3724 720-724 RB denotes fine
T3725 724-725 HYPH denotes -
T3723 725-732 VBG denotes mapping
T3726 733-735 IN denotes of
T3727 736-739 NN denotes QTL
T3728 739-740 . denotes .
T3729 740-997 sentence denotes Several studies of this CSS panel, B6 Chr1-19, X, YA/J, have been reported for behavior [12], weight gain [13], sterols [13], and plasma amino acids levels [13,14], and have identified many more QTL than studies of the same traits using a genome-wide scan.
T3730 741-748 JJ denotes Several
T3731 749-756 NNS denotes studies
T3733 757-759 IN denotes of
T3734 760-764 DT denotes this
T3736 765-768 NN denotes CSS
T3735 769-774 NN denotes panel
T3737 774-776 , denotes ,
T3738 776-778 NN denotes B6
T3740 779-783 NN denotes Chr1
T3741 783-784 HYPH denotes -
T3739 784-786 NN denotes 19
T3742 786-788 , denotes ,
T3743 788-789 NN denotes X
T3744 789-791 , denotes ,
T3745 791-793 NN denotes YA
T3747 793-794 HYPH denotes /
T3746 794-795 NN denotes J
T3748 795-797 , denotes ,
T3749 797-801 VBP denotes have
T3750 802-806 VBN denotes been
T3732 807-815 VBN denotes reported
T3751 816-819 IN denotes for
T3752 820-828 NN denotes behavior
T3753 829-830 -LRB- denotes [
T3754 830-832 CD denotes 12
T3755 832-833 -RRB- denotes ]
T3756 833-835 , denotes ,
T3757 835-841 NN denotes weight
T3758 842-846 NN denotes gain
T3759 847-848 -LRB- denotes [
T3760 848-850 CD denotes 13
T3761 850-851 -RRB- denotes ]
T3762 851-853 , denotes ,
T3763 853-860 NNS denotes sterols
T3764 861-862 -LRB- denotes [
T3765 862-864 CD denotes 13
T3766 864-865 -RRB- denotes ]
T3767 865-867 , denotes ,
T3768 867-870 CC denotes and
T3769 871-877 NN denotes plasma
T3771 878-883 NN denotes amino
T3772 884-889 NNS denotes acids
T3770 890-896 NNS denotes levels
T3773 897-898 -LRB- denotes [
T3775 898-900 CD denotes 13
T3776 900-901 , denotes ,
T3774 901-903 CD denotes 14
T3777 903-904 -RRB- denotes ]
T3778 904-906 , denotes ,
T3779 906-909 CC denotes and
T3780 910-914 VBP denotes have
T3781 915-925 VBN denotes identified
T3782 926-930 JJ denotes many
T3783 931-935 JJR denotes more
T3784 936-939 NN denotes QTL
T3785 940-944 IN denotes than
T3786 945-952 NNS denotes studies
T3787 953-955 IN denotes of
T3788 956-959 DT denotes the
T3790 960-964 JJ denotes same
T3789 965-971 NNS denotes traits
T3791 972-977 VBG denotes using
T3792 978-979 DT denotes a
T3794 980-986 NN denotes genome
T3796 986-987 HYPH denotes -
T3795 987-991 JJ denotes wide
T3793 992-996 NN denotes scan
T3797 996-997 . denotes .
R1000 T3708 T3707 prep of,presence
R1001 T3709 T3710 amod other,QTL
R1002 T3738 T3739 compound B6,19
R1003 T3710 T3708 pobj QTL,of
R1004 T3711 T3698 punct .,is
R1005 T3739 T3735 appos 19,panel
R1006 T3713 T3714 prep In,simplify
R1007 T3740 T3739 compound Chr1,19
R1008 T3715 T3713 pobj addition,In
R1009 T3716 T3714 punct ", ",simplify
R1010 T3717 T3718 amod initial,screens
R1011 T3718 T3714 nsubj screens,simplify
R1012 T3741 T3739 punct -,19
R1013 T3719 T3718 prep with,screens
R1014 T3720 T3721 det the,CSS
R1015 T3742 T3739 punct ", ",19
R1016 T3721 T3719 pobj CSS,with
R1017 T3722 T3723 det the,mapping
R1018 T3743 T3739 appos X,19
R1019 T3723 T3714 dobj mapping,simplify
R1020 T3744 T3739 punct ", ",19
R1021 T3724 T3723 advmod fine,mapping
R1022 T3725 T3723 punct -,mapping
R1023 T3745 T3746 compound YA,J
R1024 T3726 T3723 prep of,mapping
R1025 T3727 T3726 pobj QTL,of
R1026 T3746 T3739 appos J,19
R1027 T3747 T3746 punct /,J
R1028 T3748 T3732 punct ", ",reported
R1030 T3749 T3732 aux have,reported
R1032 T3750 T3732 auxpass been,reported
R1035 T3751 T3732 prep for,reported
R1038 T3752 T3751 pobj behavior,for
R1042 T3753 T3754 punct [,12
R1045 T3754 T3752 parataxis 12,behavior
R1049 T3755 T3754 punct ],12
R1053 T3756 T3752 punct ", ",behavior
R1056 T3757 T3758 compound weight,gain
R1058 T3758 T3752 conj gain,behavior
R1063 T3759 T3760 punct [,13
R1066 T3760 T3758 parataxis 13,gain
R1070 T3761 T3760 punct ],13
R1074 T3762 T3758 punct ", ",gain
R1076 T3763 T3758 conj sterols,gain
R1079 T3764 T3765 punct [,13
R1086 T3765 T3763 parataxis 13,sterols
R1090 T3766 T3765 punct ],13
R1093 T3767 T3763 punct ", ",sterols
R1098 T3768 T3763 cc and,sterols
R1101 T3769 T3770 compound plasma,levels
R1105 T3770 T3763 conj levels,sterols
R1106 T3771 T3772 compound amino,acids
R1108 T3772 T3770 compound acids,levels
R1111 T3773 T3774 punct [,14
R1114 T3774 T3770 parataxis 14,levels
R1118 T3775 T3774 nummod 13,14
R1121 T3776 T3774 punct ",",14
R1125 T3777 T3774 punct ],14
R1128 T3778 T3732 punct ", ",reported
R1131 T3779 T3732 cc and,reported
R1136 T3780 T3781 aux have,identified
R1141 T3781 T3732 conj identified,reported
R1145 T3782 T3783 amod many,more
R1148 T3783 T3784 amod more,QTL
R1152 T3784 T3781 dobj QTL,identified
R1154 T3785 T3784 prep than,QTL
R1155 T3786 T3785 pobj studies,than
R1156 T3787 T3786 prep of,studies
R1157 T3788 T3789 det the,traits
R1158 T3789 T3787 pobj traits,of
R1159 T3790 T3789 amod same,traits
R1160 T3791 T3786 acl using,studies
R1161 T3792 T3793 det a,scan
R1162 T3793 T3791 dobj scan,using
R1163 T3794 T3795 npadvmod genome,wide
R1164 T3795 T3793 amod wide,scan
R1165 T3796 T3795 punct -,wide
R1166 T3797 T3732 punct .,reported
R826 T3571 T3572 nsubjpass panel,generated
R828 T3573 T3571 prep of,panel
R829 T3574 T3575 compound chromosome,strains
R831 T3575 T3573 pobj strains,of
R832 T3576 T3575 compound substitution,strains
R834 T3577 T3575 punct (,strains
R835 T3578 T3575 appos CSS,strains
R837 T3579 T3572 punct ),generated
R838 T3580 T3572 auxpass was,generated
R839 T3581 T3582 punct [,11
R841 T3582 T3572 parataxis 11,generated
R842 T3583 T3582 punct ],11
R843 T3584 T3572 agent by,generated
R845 T3585 T3586 det a,program
R846 T3586 T3584 pobj program,by
R847 T3587 T3586 punct """",program
R849 T3588 T3589 npadvmod marker,assisted
R850 T3589 T3586 amod assisted,program
R851 T3590 T3589 punct -,assisted
R852 T3591 T3586 punct """",program
R854 T3592 T3586 compound breeding,program
R855 T3593 T3594 advmod where,backcrossed
R856 T3594 T3586 relcl backcrossed,program
R858 T3595 T3596 det the,progeny
R859 T3596 T3594 nsubjpass progeny,backcrossed
R860 T3597 T3596 prep of,progeny
R861 T3598 T3599 det a,cross
R863 T3599 T3597 pobj cross,of
R864 T3600 T3599 nmod B6,cross
R866 T3601 T3600 punct ×,B6
R867 T3602 T3603 compound A,J
R868 T3603 T3600 appos J,B6
R869 T3604 T3603 punct /,J
R871 T3605 T3594 auxpass were,backcrossed
R872 T3606 T3594 advmod successively,backcrossed
R873 T3607 T3594 prep to,backcrossed
R874 T3608 T3609 det the,mice
R875 T3609 T3607 pobj mice,to
R876 T3610 T3609 compound B6,mice
R878 T3611 T3572 punct .,generated
R879 T3613 T3614 amod Genetic,markers
R881 T3614 T3615 nsubjpass markers,used
R883 T3616 T3615 auxpass were,used
R884 T3617 T3618 aux to,identify
R885 T3618 T3615 advcl identify,used
R886 T3619 T3618 dobj homozygosity,identify
R888 T3620 T3619 prep in,homozygosity
R889 T3621 T3622 det the,B6
R894 T3622 T3620 pobj B6,in
R895 T3623 T3622 nmod background,B6
R896 T3624 T3622 punct (,B6
R898 T3625 T3622 punct ),B6
R899 T3626 T3622 cc and,B6
R901 T3627 T3628 det the,J
R902 T3628 T3632 compound J,chromosome
R903 T3629 T3628 amod individual,J
R905 T3630 T3628 compound A,J
R906 T3631 T3628 punct /,J
R907 T3632 T3622 conj chromosome,B6
R909 T3633 T3615 punct .,used
R912 T3635 T3636 det These,strains
R914 T3636 T3637 nsubj strains,have
R916 T3638 T3639 nummod one,chromosome
R917 T3639 T3637 dobj chromosome,have
R918 T3640 T3639 prep from,chromosome
R920 T3641 T3642 compound A,J
R921 T3642 T3644 compound J,mice
R922 T3643 T3642 punct /,J
R924 T3644 T3640 pobj mice,from
R925 T3645 T3637 prep in,have
R926 T3646 T3647 det a,background
R927 T3647 T3645 pobj background,in
R928 T3648 T3647 compound B6,background
R930 T3649 T3637 punct .,have
R931 T3651 T3652 nsubj This,allows
R933 T3653 T3654 det the,identification
R934 T3654 T3652 dobj identification,allows
R936 T3655 T3654 prep of,identification
R937 T3656 T3657 det a,trait
R938 T3657 T3655 pobj trait,of
R940 T3658 T3657 prep in,trait
R941 T3659 T3660 nummod one,CSS
R943 T3660 T3658 pobj CSS,in
R944 T3661 T3659 cc or,one
R945 T3662 T3659 conj more,one
R947 T3663 T3652 cc and,allows
R948 T3664 T3652 conj implies,allows
R950 T3665 T3666 mark that,resides
R951 T3666 T3664 ccomp resides,implies
R952 T3667 T3668 advmod at,one
R954 T3668 T3670 nummod one,QTL
R955 T3669 T3668 advmod least,one
R956 T3670 T3666 nsubj QTL,resides
R958 T3671 T3666 prep on,resides
R959 T3672 T3673 det this,chromosome
R960 T3673 T3671 pobj chromosome,on
R962 T3674 T3652 punct .,allows
R963 T3676 T3677 nsubj Use,requires
R964 T3728 T3714 punct .,simplify
R965 T3678 T3676 prep of,Use
R966 T3679 T3680 det this,panel
R967 T3680 T3678 pobj panel,of
R968 T3730 T3731 amod Several,studies
R969 T3681 T3682 amod fewer,mice
R970 T3682 T3677 dobj mice,requires
R971 T3683 T3684 aux to,determine
R972 T3684 T3677 advcl determine,requires
R973 T3685 T3686 det the,QTL
R974 T3731 T3732 nsubjpass studies,reported
R975 T3686 T3684 dobj QTL,determine
R976 T3687 T3688 mark than,does
R977 T3688 T3677 advcl does,requires
R978 T3689 T3690 det a,scan
R979 T3690 T3688 nsubj scan,does
R980 T3691 T3692 npadvmod genome,wide
R981 T3692 T3690 amod wide,scan
R982 T3733 T3731 prep of,studies
R983 T3693 T3692 punct -,wide
R984 T3694 T3677 punct .,requires
R985 T3696 T3697 det Another,advantage
R986 T3734 T3735 det this,panel
R987 T3697 T3698 nsubj advantage,is
R988 T3699 T3700 det the,ability
R989 T3735 T3733 pobj panel,of
R990 T3700 T3698 attr ability,is
R991 T3701 T3700 prep for,ability
R992 T3702 T3701 pobj detection,for
R993 T3703 T3702 prep of,detection
R994 T3736 T3735 compound CSS,panel
R995 T3704 T3703 pobj QTL,of
R996 T3705 T3702 prep in,detection
R997 T3706 T3707 det the,presence
R998 T3737 T3735 punct ", ",panel
R999 T3707 T3705 pobj presence,in