Id |
Subject |
Object |
Predicate |
Lexical cue |
T5706 |
0-8 |
JJ |
denotes |
Clinical |
T5707 |
9-17 |
NN |
denotes |
evidence |
T5709 |
18-20 |
IN |
denotes |
in |
T5710 |
21-28 |
NN |
denotes |
support |
T5711 |
29-31 |
IN |
denotes |
of |
T5712 |
32-36 |
DT |
denotes |
this |
T5713 |
37-47 |
NN |
denotes |
hypothesis |
T5708 |
48-53 |
VBZ |
denotes |
comes |
T5714 |
54-58 |
IN |
denotes |
from |
T5715 |
59-60 |
DT |
denotes |
a |
T5716 |
61-67 |
NN |
denotes |
number |
T5717 |
68-70 |
IN |
denotes |
of |
T5718 |
71-73 |
NN |
denotes |
XP |
T5720 |
74-89 |
NN |
denotes |
complementation |
T5721 |
90-95 |
NN |
denotes |
group |
T5722 |
96-97 |
NN |
denotes |
D |
T5719 |
98-106 |
NNS |
denotes |
patients |
T5723 |
107-111 |
WDT |
denotes |
that |
T5725 |
112-114 |
VBP |
denotes |
do |
T5726 |
115-118 |
RB |
denotes |
not |
T5724 |
119-122 |
VB |
denotes |
fit |
T5727 |
123-129 |
IN |
denotes |
within |
T5728 |
130-133 |
DT |
denotes |
the |
T5729 |
134-143 |
NN |
denotes |
framework |
T5730 |
144-146 |
IN |
denotes |
of |
T5731 |
147-150 |
DT |
denotes |
the |
T5733 |
151-158 |
JJ |
denotes |
current |
T5734 |
159-170 |
JJ |
denotes |
monoallelic |
T5732 |
171-179 |
NN |
denotes |
paradigm |
T5735 |
180-182 |
IN |
denotes |
of |
T5736 |
183-186 |
NN |
denotes |
XPD |
T5737 |
187-196 |
NNS |
denotes |
disorders |
T5738 |
197-198 |
-LRB- |
denotes |
( |
T5739 |
198-204 |
NN |
denotes |
Figure |
T5740 |
205-206 |
CD |
denotes |
5 |
T5741 |
206-207 |
-RRB- |
denotes |
) |
T5742 |
207-208 |
. |
denotes |
. |
T5743 |
208-636 |
sentence |
denotes |
In contrast to two hemizygous XPDXPCS patients carrying the XPDG47R- or XPDR666W-encoding alleles who died of the disease before 2 y of age, two compound heterozygous XPDXPCS patients carrying the same XPDG47R- or XPDR666W-encoding alleles in addition to the presumed null XPDL461V+del716−730 both had considerably milder disease symptoms and survived more than ten times longer (A. Lehmann, personal communication) (Figure 5). |
T5744 |
209-211 |
IN |
denotes |
In |
T5746 |
212-220 |
NN |
denotes |
contrast |
T5747 |
221-223 |
IN |
denotes |
to |
T5748 |
224-227 |
CD |
denotes |
two |
T5750 |
228-238 |
JJ |
denotes |
hemizygous |
T5751 |
239-246 |
NN |
denotes |
XPDXPCS |
T5749 |
247-255 |
NNS |
denotes |
patients |
T5752 |
256-264 |
VBG |
denotes |
carrying |
T5753 |
265-268 |
DT |
denotes |
the |
T5755 |
269-276 |
NN |
denotes |
XPDG47R |
T5757 |
276-277 |
HYPH |
denotes |
- |
T5758 |
278-280 |
CC |
denotes |
or |
T5759 |
281-289 |
NN |
denotes |
XPDR666W |
T5760 |
289-290 |
HYPH |
denotes |
- |
T5756 |
290-298 |
VBG |
denotes |
encoding |
T5754 |
299-306 |
NNS |
denotes |
alleles |
T5761 |
307-310 |
WP |
denotes |
who |
T5762 |
311-315 |
VBD |
denotes |
died |
T5763 |
316-318 |
IN |
denotes |
of |
T5764 |
319-322 |
DT |
denotes |
the |
T5765 |
323-330 |
NN |
denotes |
disease |
T5766 |
331-337 |
IN |
denotes |
before |
T5767 |
338-339 |
CD |
denotes |
2 |
T5768 |
340-341 |
NNS |
denotes |
y |
T5769 |
342-344 |
IN |
denotes |
of |
T5770 |
345-348 |
NN |
denotes |
age |
T5771 |
348-350 |
, |
denotes |
, |
T5772 |
350-353 |
CD |
denotes |
two |
T5774 |
354-362 |
JJ |
denotes |
compound |
T5775 |
363-375 |
JJ |
denotes |
heterozygous |
T5776 |
376-383 |
NN |
denotes |
XPDXPCS |
T5773 |
384-392 |
NNS |
denotes |
patients |
T5777 |
393-401 |
VBG |
denotes |
carrying |
T5778 |
402-405 |
DT |
denotes |
the |
T5780 |
406-410 |
JJ |
denotes |
same |
T5781 |
411-418 |
NN |
denotes |
XPDG47R |
T5783 |
418-419 |
HYPH |
denotes |
- |
T5784 |
420-422 |
CC |
denotes |
or |
T5785 |
423-431 |
NN |
denotes |
XPDR666W |
T5786 |
431-432 |
HYPH |
denotes |
- |
T5782 |
432-440 |
VBG |
denotes |
encoding |
T5779 |
441-448 |
NNS |
denotes |
alleles |
T5787 |
449-451 |
IN |
denotes |
in |
T5788 |
452-460 |
NN |
denotes |
addition |
T5789 |
461-463 |
IN |
denotes |
to |
T5790 |
464-467 |
DT |
denotes |
the |
T5792 |
468-476 |
VBN |
denotes |
presumed |
T5793 |
477-481 |
JJ |
denotes |
null |
T5794 |
482-490 |
NN |
denotes |
XPDL461V |
T5795 |
490-491 |
SYM |
denotes |
+ |
T5796 |
491-497 |
NN |
denotes |
del716 |
T5797 |
497-498 |
HYPH |
denotes |
− |
T5791 |
498-501 |
NN |
denotes |
730 |
T5798 |
502-506 |
DT |
denotes |
both |
T5745 |
507-510 |
VBD |
denotes |
had |
T5799 |
511-523 |
RB |
denotes |
considerably |
T5800 |
524-530 |
JJR |
denotes |
milder |
T5802 |
531-538 |
NN |
denotes |
disease |
T5801 |
539-547 |
NNS |
denotes |
symptoms |
T5803 |
548-551 |
CC |
denotes |
and |
T5804 |
552-560 |
VBD |
denotes |
survived |
T5805 |
561-565 |
JJR |
denotes |
more |
T5807 |
566-570 |
IN |
denotes |
than |
T5806 |
571-574 |
CD |
denotes |
ten |
T5808 |
575-580 |
NNS |
denotes |
times |
T5809 |
581-587 |
RBR |
denotes |
longer |
T5810 |
588-589 |
-LRB- |
denotes |
( |
T5811 |
589-591 |
NNP |
denotes |
A. |
T5812 |
592-599 |
NNP |
denotes |
Lehmann |
T5813 |
599-601 |
, |
denotes |
, |
T5814 |
601-609 |
JJ |
denotes |
personal |
T5815 |
610-623 |
NN |
denotes |
communication |
T5816 |
623-624 |
-RRB- |
denotes |
) |
T5817 |
625-626 |
-LRB- |
denotes |
( |
T5818 |
626-632 |
NN |
denotes |
Figure |
T5819 |
633-634 |
CD |
denotes |
5 |
T5820 |
634-635 |
-RRB- |
denotes |
) |
T5821 |
635-636 |
. |
denotes |
. |
T5822 |
636-751 |
sentence |
denotes |
Compound heterozygosity is also associated with the recently reported combination XP and TTD (XPTTD) syndrome [8]. |
T5823 |
637-645 |
NN |
denotes |
Compound |
T5824 |
646-660 |
NN |
denotes |
heterozygosity |
T5826 |
661-663 |
VBZ |
denotes |
is |
T5827 |
664-668 |
RB |
denotes |
also |
T5825 |
669-679 |
VBN |
denotes |
associated |
T5828 |
680-684 |
IN |
denotes |
with |
T5829 |
685-688 |
DT |
denotes |
the |
T5831 |
689-697 |
RB |
denotes |
recently |
T5832 |
698-706 |
VBN |
denotes |
reported |
T5833 |
707-718 |
NN |
denotes |
combination |
T5834 |
719-721 |
NN |
denotes |
XP |
T5835 |
722-725 |
CC |
denotes |
and |
T5836 |
726-729 |
NN |
denotes |
TTD |
T5837 |
730-731 |
-LRB- |
denotes |
( |
T5838 |
731-736 |
NN |
denotes |
XPTTD |
T5839 |
736-737 |
-RRB- |
denotes |
) |
T5830 |
738-746 |
NN |
denotes |
syndrome |
T5840 |
747-748 |
-LRB- |
denotes |
[ |
T5841 |
748-749 |
CD |
denotes |
8 |
T5842 |
749-750 |
-RRB- |
denotes |
] |
T5843 |
750-751 |
. |
denotes |
. |
T5844 |
751-896 |
sentence |
denotes |
Similar to the XpdTTD/†XPCS and XpdTTD/†XP mice described here, both patients with XPTTD described so far had intermediate hair cysteine values. |
T5845 |
752-759 |
JJ |
denotes |
Similar |
T5847 |
760-762 |
IN |
denotes |
to |
T5848 |
763-766 |
DT |
denotes |
the |
T5850 |
767-773 |
NN |
denotes |
XpdTTD |
T5852 |
773-774 |
HYPH |
denotes |
/ |
T5851 |
774-779 |
NN |
denotes |
†XPCS |
T5853 |
780-783 |
CC |
denotes |
and |
T5854 |
784-790 |
NN |
denotes |
XpdTTD |
T5856 |
790-791 |
HYPH |
denotes |
/ |
T5855 |
791-794 |
NN |
denotes |
†XP |
T5849 |
795-799 |
NNS |
denotes |
mice |
T5857 |
800-809 |
VBN |
denotes |
described |
T5858 |
810-814 |
RB |
denotes |
here |
T5859 |
814-816 |
, |
denotes |
, |
T5860 |
816-820 |
DT |
denotes |
both |
T5861 |
821-829 |
NNS |
denotes |
patients |
T5862 |
830-834 |
IN |
denotes |
with |
T5863 |
835-840 |
NN |
denotes |
XPTTD |
T5864 |
841-850 |
VBN |
denotes |
described |
T5865 |
851-853 |
RB |
denotes |
so |
T5866 |
854-857 |
RB |
denotes |
far |
T5846 |
858-861 |
VBD |
denotes |
had |
T5867 |
862-874 |
JJ |
denotes |
intermediate |
T5869 |
875-879 |
NN |
denotes |
hair |
T5870 |
880-888 |
NN |
denotes |
cysteine |
T5868 |
889-895 |
NNS |
denotes |
values |
T5871 |
895-896 |
. |
denotes |
. |
T5872 |
896-1038 |
sentence |
denotes |
Furthermore, XPTTD patient XP38BR carried a “causative” TTD mutation in one allele and a novel point mutation encoding XPDL485P in the other. |
T5873 |
897-908 |
RB |
denotes |
Furthermore |
T5875 |
908-910 |
, |
denotes |
, |
T5876 |
910-915 |
NN |
denotes |
XPTTD |
T5878 |
916-923 |
NN |
denotes |
patient |
T5877 |
924-930 |
NN |
denotes |
XP38BR |
T5874 |
931-938 |
VBD |
denotes |
carried |
T5879 |
939-940 |
DT |
denotes |
a |
T5881 |
941-942 |
`` |
denotes |
“ |
T5882 |
942-951 |
JJ |
denotes |
causative |
T5883 |
951-952 |
'' |
denotes |
” |
T5884 |
953-956 |
NN |
denotes |
TTD |
T5880 |
957-965 |
NN |
denotes |
mutation |
T5885 |
966-968 |
IN |
denotes |
in |
T5886 |
969-972 |
CD |
denotes |
one |
T5887 |
973-979 |
NN |
denotes |
allele |
T5888 |
980-983 |
CC |
denotes |
and |
T5889 |
984-985 |
DT |
denotes |
a |
T5891 |
986-991 |
JJ |
denotes |
novel |
T5892 |
992-997 |
NN |
denotes |
point |
T5890 |
998-1006 |
NN |
denotes |
mutation |
T5893 |
1007-1015 |
VBG |
denotes |
encoding |
T5894 |
1016-1024 |
NN |
denotes |
XPDL485P |
T5895 |
1025-1027 |
IN |
denotes |
in |
T5896 |
1028-1031 |
DT |
denotes |
the |
T5897 |
1032-1037 |
JJ |
denotes |
other |
T5898 |
1037-1038 |
. |
denotes |
. |
T5899 |
1038-1326 |
sentence |
denotes |
Although the XPDL485P-encoding allele fails to complement viability in the haploid S. pombe rad15 deletion strain and is thus interpretable as a null allele [8], we nonetheless suggest that the combined XPTTD phenotype in this patient involves phenotypic contributions from both alleles. |
T5900 |
1039-1047 |
IN |
denotes |
Although |
T5902 |
1048-1051 |
DT |
denotes |
the |
T5904 |
1052-1060 |
NN |
denotes |
XPDL485P |
T5906 |
1060-1061 |
HYPH |
denotes |
- |
T5905 |
1061-1069 |
VBG |
denotes |
encoding |
T5903 |
1070-1076 |
NN |
denotes |
allele |
T5901 |
1077-1082 |
VBZ |
denotes |
fails |
T5908 |
1083-1085 |
TO |
denotes |
to |
T5909 |
1086-1096 |
VB |
denotes |
complement |
T5910 |
1097-1106 |
NN |
denotes |
viability |
T5911 |
1107-1109 |
IN |
denotes |
in |
T5912 |
1110-1113 |
DT |
denotes |
the |
T5914 |
1114-1121 |
JJ |
denotes |
haploid |
T5915 |
1122-1124 |
FW |
denotes |
S. |
T5916 |
1125-1130 |
FW |
denotes |
pombe |
T5917 |
1131-1136 |
NN |
denotes |
rad15 |
T5918 |
1137-1145 |
NN |
denotes |
deletion |
T5913 |
1146-1152 |
NN |
denotes |
strain |
T5919 |
1153-1156 |
CC |
denotes |
and |
T5920 |
1157-1159 |
VBZ |
denotes |
is |
T5921 |
1160-1164 |
RB |
denotes |
thus |
T5922 |
1165-1178 |
JJ |
denotes |
interpretable |
T5923 |
1179-1181 |
IN |
denotes |
as |
T5924 |
1182-1183 |
DT |
denotes |
a |
T5926 |
1184-1188 |
JJ |
denotes |
null |
T5925 |
1189-1195 |
NN |
denotes |
allele |
T5927 |
1196-1197 |
-LRB- |
denotes |
[ |
T5928 |
1197-1198 |
CD |
denotes |
8 |
T5929 |
1198-1199 |
-RRB- |
denotes |
] |
T5930 |
1199-1201 |
, |
denotes |
, |
T5931 |
1201-1203 |
PRP |
denotes |
we |
T5932 |
1204-1215 |
RB |
denotes |
nonetheless |
T5907 |
1216-1223 |
VBP |
denotes |
suggest |
T5933 |
1224-1228 |
IN |
denotes |
that |
T5935 |
1229-1232 |
DT |
denotes |
the |
T5937 |
1233-1241 |
JJ |
denotes |
combined |
T5938 |
1242-1247 |
NN |
denotes |
XPTTD |
T5936 |
1248-1257 |
NN |
denotes |
phenotype |
T5939 |
1258-1260 |
IN |
denotes |
in |
T5940 |
1261-1265 |
DT |
denotes |
this |
T5941 |
1266-1273 |
NN |
denotes |
patient |
T5934 |
1274-1282 |
VBZ |
denotes |
involves |
T5942 |
1283-1293 |
JJ |
denotes |
phenotypic |
T5943 |
1294-1307 |
NNS |
denotes |
contributions |
T5944 |
1308-1312 |
IN |
denotes |
from |
T5945 |
1313-1317 |
DT |
denotes |
both |
T5946 |
1318-1325 |
NNS |
denotes |
alleles |
T5947 |
1325-1326 |
. |
denotes |
. |
T5948 |
1326-1459 |
sentence |
denotes |
Taken together, these data suggest a shift to a biallelic paradigm for compound heterozygous patients in XP complementation group D. |
T5949 |
1327-1332 |
VBN |
denotes |
Taken |
T5951 |
1333-1341 |
RB |
denotes |
together |
T5952 |
1341-1343 |
, |
denotes |
, |
T5953 |
1343-1348 |
DT |
denotes |
these |
T5954 |
1349-1353 |
NNS |
denotes |
data |
T5950 |
1354-1361 |
VBP |
denotes |
suggest |
T5955 |
1362-1363 |
DT |
denotes |
a |
T5956 |
1364-1369 |
NN |
denotes |
shift |
T5957 |
1370-1372 |
IN |
denotes |
to |
T5958 |
1373-1374 |
DT |
denotes |
a |
T5960 |
1375-1384 |
JJ |
denotes |
biallelic |
T5959 |
1385-1393 |
NN |
denotes |
paradigm |
T5961 |
1394-1397 |
IN |
denotes |
for |
T5962 |
1398-1406 |
NN |
denotes |
compound |
T5964 |
1407-1419 |
JJ |
denotes |
heterozygous |
T5963 |
1420-1428 |
NNS |
denotes |
patients |
T5965 |
1429-1431 |
IN |
denotes |
in |
T5966 |
1432-1434 |
NN |
denotes |
XP |
T5968 |
1435-1450 |
NN |
denotes |
complementation |
T5969 |
1451-1456 |
NN |
denotes |
group |
T5967 |
1457-1458 |
NN |
denotes |
D |
T5970 |
1458-1459 |
. |
denotes |
. |
R3848 |
T5706 |
T5707 |
amod |
Clinical,evidence |
R3849 |
T5707 |
T5708 |
nsubj |
evidence,comes |
R3850 |
T5709 |
T5707 |
prep |
in,evidence |
R3851 |
T5710 |
T5709 |
pobj |
support,in |
R3852 |
T5711 |
T5710 |
prep |
of,support |
R3853 |
T5712 |
T5713 |
det |
this,hypothesis |
R3854 |
T5713 |
T5711 |
pobj |
hypothesis,of |
R3855 |
T5714 |
T5708 |
prep |
from,comes |
R3856 |
T5715 |
T5716 |
det |
a,number |
R3857 |
T5716 |
T5714 |
pobj |
number,from |
R3858 |
T5717 |
T5716 |
prep |
of,number |
R3859 |
T5718 |
T5719 |
compound |
XP,patients |
R3860 |
T5719 |
T5717 |
pobj |
patients,of |
R3861 |
T5720 |
T5719 |
compound |
complementation,patients |
R3862 |
T5721 |
T5722 |
compound |
group,D |
R3863 |
T5722 |
T5719 |
compound |
D,patients |
R3864 |
T5723 |
T5724 |
dep |
that,fit |
R3865 |
T5724 |
T5719 |
relcl |
fit,patients |
R3866 |
T5725 |
T5724 |
aux |
do,fit |
R3867 |
T5726 |
T5724 |
neg |
not,fit |
R3868 |
T5727 |
T5724 |
prep |
within,fit |
R3869 |
T5728 |
T5729 |
det |
the,framework |
R3870 |
T5729 |
T5727 |
pobj |
framework,within |
R3871 |
T5730 |
T5729 |
prep |
of,framework |
R3872 |
T5731 |
T5732 |
det |
the,paradigm |
R3873 |
T5732 |
T5730 |
pobj |
paradigm,of |
R3874 |
T5733 |
T5732 |
amod |
current,paradigm |
R3875 |
T5734 |
T5732 |
amod |
monoallelic,paradigm |
R3876 |
T5735 |
T5732 |
prep |
of,paradigm |
R3877 |
T5736 |
T5737 |
compound |
XPD,disorders |
R3878 |
T5737 |
T5735 |
pobj |
disorders,of |
R3879 |
T5738 |
T5739 |
punct |
(,Figure |
R3880 |
T5739 |
T5708 |
parataxis |
Figure,comes |
R3881 |
T5740 |
T5739 |
nummod |
5,Figure |
R3882 |
T5741 |
T5739 |
punct |
),Figure |
R3883 |
T5742 |
T5708 |
punct |
.,comes |
R3884 |
T5744 |
T5745 |
prep |
In,had |
R3885 |
T5746 |
T5744 |
pobj |
contrast,In |
R3886 |
T5747 |
T5746 |
prep |
to,contrast |
R3887 |
T5748 |
T5749 |
nummod |
two,patients |
R3888 |
T5749 |
T5747 |
pobj |
patients,to |
R3889 |
T5750 |
T5749 |
amod |
hemizygous,patients |
R3890 |
T5751 |
T5749 |
compound |
XPDXPCS,patients |
R3891 |
T5752 |
T5749 |
acl |
carrying,patients |
R3892 |
T5753 |
T5754 |
det |
the,alleles |
R3893 |
T5754 |
T5752 |
dobj |
alleles,carrying |
R3894 |
T5755 |
T5756 |
npadvmod |
XPDG47R,encoding |
R3895 |
T5756 |
T5754 |
amod |
encoding,alleles |
R3896 |
T5757 |
T5755 |
punct |
-,XPDG47R |
R3897 |
T5758 |
T5755 |
cc |
or,XPDG47R |
R3898 |
T5759 |
T5755 |
conj |
XPDR666W,XPDG47R |
R3899 |
T5760 |
T5756 |
punct |
-,encoding |
R3900 |
T5761 |
T5762 |
dep |
who,died |
R3901 |
T5762 |
T5754 |
relcl |
died,alleles |
R3902 |
T5763 |
T5762 |
prep |
of,died |
R3903 |
T5764 |
T5765 |
det |
the,disease |
R3904 |
T5765 |
T5763 |
pobj |
disease,of |
R3905 |
T5766 |
T5762 |
prep |
before,died |
R3906 |
T5767 |
T5768 |
nummod |
2,y |
R3907 |
T5768 |
T5766 |
pobj |
y,before |
R3908 |
T5769 |
T5768 |
prep |
of,y |
R3909 |
T5770 |
T5769 |
pobj |
age,of |
R3910 |
T5771 |
T5745 |
punct |
", ",had |
R3911 |
T5772 |
T5773 |
nummod |
two,patients |
R3912 |
T5773 |
T5745 |
nsubj |
patients,had |
R3913 |
T5774 |
T5773 |
amod |
compound,patients |
R3914 |
T5775 |
T5773 |
amod |
heterozygous,patients |
R3915 |
T5776 |
T5773 |
compound |
XPDXPCS,patients |
R3916 |
T5777 |
T5773 |
acl |
carrying,patients |
R3917 |
T5778 |
T5779 |
det |
the,alleles |
R3918 |
T5779 |
T5777 |
dobj |
alleles,carrying |
R3919 |
T5780 |
T5779 |
amod |
same,alleles |
R3920 |
T5781 |
T5782 |
npadvmod |
XPDG47R,encoding |
R3921 |
T5782 |
T5779 |
amod |
encoding,alleles |
R3922 |
T5783 |
T5781 |
punct |
-,XPDG47R |
R3923 |
T5784 |
T5781 |
cc |
or,XPDG47R |
R3924 |
T5785 |
T5781 |
conj |
XPDR666W,XPDG47R |
R3925 |
T5786 |
T5782 |
punct |
-,encoding |
R3926 |
T5787 |
T5779 |
prep |
in,alleles |
R3927 |
T5788 |
T5787 |
pobj |
addition,in |
R3928 |
T5789 |
T5788 |
prep |
to,addition |
R3929 |
T5790 |
T5791 |
det |
the,730 |
R3930 |
T5791 |
T5789 |
pobj |
730,to |
R3931 |
T5792 |
T5793 |
advmod |
presumed,null |
R3932 |
T5793 |
T5791 |
amod |
null,730 |
R3933 |
T5794 |
T5791 |
nmod |
XPDL461V,730 |
R3934 |
T5795 |
T5791 |
punct |
+,730 |
R3935 |
T5796 |
T5791 |
compound |
del716,730 |
R3936 |
T5797 |
T5791 |
punct |
−,730 |
R3937 |
T5798 |
T5773 |
appos |
both,patients |
R3938 |
T5799 |
T5800 |
advmod |
considerably,milder |
R3939 |
T5800 |
T5801 |
amod |
milder,symptoms |
R3940 |
T5801 |
T5745 |
dobj |
symptoms,had |
R3941 |
T5802 |
T5801 |
compound |
disease,symptoms |
R3942 |
T5803 |
T5745 |
cc |
and,had |
R3943 |
T5804 |
T5745 |
conj |
survived,had |
R3944 |
T5805 |
T5806 |
amod |
more,ten |
R3945 |
T5806 |
T5808 |
nummod |
ten,times |
R3946 |
T5807 |
T5806 |
quantmod |
than,ten |
R3947 |
T5808 |
T5809 |
npadvmod |
times,longer |
R3948 |
T5809 |
T5804 |
advmod |
longer,survived |
R3949 |
T5810 |
T5811 |
punct |
(,A. |
R3950 |
T5811 |
T5804 |
meta |
A.,survived |
R3951 |
T5812 |
T5811 |
nmod |
Lehmann,A. |
R3952 |
T5813 |
T5811 |
punct |
", ",A. |
R3953 |
T5814 |
T5811 |
amod |
personal,A. |
R3954 |
T5815 |
T5811 |
nmod |
communication,A. |
R3955 |
T5816 |
T5811 |
punct |
),A. |
R3956 |
T5817 |
T5818 |
punct |
(,Figure |
R3957 |
T5818 |
T5804 |
parataxis |
Figure,survived |
R3958 |
T5819 |
T5818 |
nummod |
5,Figure |
R3959 |
T5820 |
T5818 |
punct |
),Figure |
R3960 |
T5821 |
T5745 |
punct |
.,had |
R3961 |
T5823 |
T5824 |
compound |
Compound,heterozygosity |
R3962 |
T5824 |
T5825 |
nsubjpass |
heterozygosity,associated |
R3963 |
T5826 |
T5825 |
auxpass |
is,associated |
R3964 |
T5827 |
T5825 |
advmod |
also,associated |
R3965 |
T5828 |
T5825 |
prep |
with,associated |
R3966 |
T5829 |
T5830 |
det |
the,syndrome |
R3967 |
T5830 |
T5828 |
pobj |
syndrome,with |
R3968 |
T5831 |
T5832 |
advmod |
recently,reported |
R3969 |
T5832 |
T5830 |
amod |
reported,syndrome |
R3970 |
T5833 |
T5830 |
nmod |
combination,syndrome |
R3971 |
T5834 |
T5830 |
nmod |
XP,syndrome |
R3972 |
T5835 |
T5834 |
cc |
and,XP |
R3973 |
T5836 |
T5834 |
conj |
TTD,XP |
R3974 |
T5837 |
T5838 |
punct |
(,XPTTD |
R3975 |
T5838 |
T5836 |
parataxis |
XPTTD,TTD |
R3976 |
T5839 |
T5838 |
punct |
),XPTTD |
R3977 |
T5840 |
T5841 |
punct |
[,8 |
R3978 |
T5841 |
T5825 |
parataxis |
8,associated |
R3979 |
T5842 |
T5841 |
punct |
],8 |
R3980 |
T5843 |
T5825 |
punct |
.,associated |
R3981 |
T5845 |
T5846 |
advcl |
Similar,had |
R3982 |
T5847 |
T5845 |
prep |
to,Similar |
R3983 |
T5848 |
T5849 |
det |
the,mice |
R3984 |
T5849 |
T5847 |
pobj |
mice,to |
R3985 |
T5850 |
T5851 |
nmod |
XpdTTD,†XPCS |
R3986 |
T5851 |
T5849 |
nmod |
†XPCS,mice |
R3987 |
T5852 |
T5851 |
punct |
/,†XPCS |
R3988 |
T5853 |
T5851 |
cc |
and,†XPCS |
R3989 |
T5854 |
T5855 |
compound |
XpdTTD,†XP |
R3990 |
T5855 |
T5851 |
conj |
†XP,†XPCS |
R3991 |
T5856 |
T5855 |
punct |
/,†XP |
R3992 |
T5857 |
T5849 |
acl |
described,mice |
R3993 |
T5858 |
T5857 |
advmod |
here,described |
R3994 |
T5859 |
T5846 |
punct |
", ",had |
R3995 |
T5860 |
T5861 |
det |
both,patients |
R3996 |
T5861 |
T5846 |
nsubj |
patients,had |
R3997 |
T5862 |
T5861 |
prep |
with,patients |
R3998 |
T5863 |
T5862 |
pobj |
XPTTD,with |
R3999 |
T5864 |
T5861 |
acl |
described,patients |
R4000 |
T5865 |
T5866 |
advmod |
so,far |
R4001 |
T5866 |
T5864 |
advmod |
far,described |
R4002 |
T5867 |
T5868 |
amod |
intermediate,values |
R4003 |
T5868 |
T5846 |
dobj |
values,had |
R4004 |
T5869 |
T5870 |
compound |
hair,cysteine |
R4005 |
T5870 |
T5868 |
compound |
cysteine,values |
R4006 |
T5871 |
T5846 |
punct |
.,had |
R4007 |
T5873 |
T5874 |
advmod |
Furthermore,carried |
R4008 |
T5875 |
T5874 |
punct |
", ",carried |
R4009 |
T5876 |
T5877 |
compound |
XPTTD,XP38BR |
R4010 |
T5877 |
T5874 |
nsubj |
XP38BR,carried |
R4011 |
T5878 |
T5877 |
compound |
patient,XP38BR |
R4012 |
T5879 |
T5880 |
det |
a,mutation |
R4013 |
T5880 |
T5874 |
dobj |
mutation,carried |
R4014 |
T5881 |
T5880 |
punct |
“,mutation |
R4015 |
T5882 |
T5880 |
amod |
causative,mutation |
R4016 |
T5883 |
T5880 |
punct |
”,mutation |
R4017 |
T5884 |
T5880 |
compound |
TTD,mutation |
R4018 |
T5885 |
T5874 |
prep |
in,carried |
R4019 |
T5886 |
T5887 |
nummod |
one,allele |
R4020 |
T5887 |
T5885 |
pobj |
allele,in |
R4021 |
T5888 |
T5874 |
cc |
and,carried |
R4022 |
T5889 |
T5890 |
det |
a,mutation |
R4023 |
T5890 |
T5874 |
conj |
mutation,carried |
R4024 |
T5891 |
T5890 |
amod |
novel,mutation |
R4025 |
T5892 |
T5890 |
compound |
point,mutation |
R4026 |
T5893 |
T5890 |
acl |
encoding,mutation |
R4027 |
T5894 |
T5893 |
dobj |
XPDL485P,encoding |
R4028 |
T5895 |
T5890 |
prep |
in,mutation |
R4029 |
T5896 |
T5897 |
det |
the,other |
R4030 |
T5897 |
T5895 |
pobj |
other,in |
R4031 |
T5898 |
T5874 |
punct |
.,carried |
R4032 |
T5900 |
T5901 |
mark |
Although,fails |
R4033 |
T5901 |
T5907 |
advcl |
fails,suggest |
R4034 |
T5902 |
T5903 |
det |
the,allele |
R4035 |
T5903 |
T5901 |
nsubj |
allele,fails |
R4036 |
T5904 |
T5905 |
npadvmod |
XPDL485P,encoding |
R4037 |
T5905 |
T5903 |
amod |
encoding,allele |
R4038 |
T5906 |
T5905 |
punct |
-,encoding |
R4039 |
T5908 |
T5909 |
aux |
to,complement |
R4040 |
T5909 |
T5901 |
xcomp |
complement,fails |
R4041 |
T5910 |
T5909 |
dobj |
viability,complement |
R4042 |
T5911 |
T5909 |
prep |
in,complement |
R4043 |
T5912 |
T5913 |
det |
the,strain |
R4044 |
T5913 |
T5911 |
pobj |
strain,in |
R4045 |
T5914 |
T5913 |
amod |
haploid,strain |
R4046 |
T5915 |
T5913 |
nmod |
S.,strain |
R4047 |
T5916 |
T5913 |
nmod |
pombe,strain |
R4048 |
T5917 |
T5913 |
compound |
rad15,strain |
R4049 |
T5918 |
T5913 |
compound |
deletion,strain |
R4050 |
T5919 |
T5901 |
cc |
and,fails |
R4051 |
T5920 |
T5901 |
conj |
is,fails |
R4052 |
T5921 |
T5920 |
advmod |
thus,is |
R4053 |
T5922 |
T5920 |
acomp |
interpretable,is |
R4054 |
T5923 |
T5922 |
prep |
as,interpretable |
R4055 |
T5924 |
T5925 |
det |
a,allele |
R4056 |
T5925 |
T5923 |
pobj |
allele,as |
R4057 |
T5926 |
T5925 |
amod |
null,allele |
R4058 |
T5927 |
T5928 |
punct |
[,8 |
R4059 |
T5928 |
T5920 |
parataxis |
8,is |
R4060 |
T5929 |
T5928 |
punct |
],8 |
R4061 |
T5930 |
T5907 |
punct |
", ",suggest |
R4062 |
T5931 |
T5907 |
nsubj |
we,suggest |
R4063 |
T5932 |
T5907 |
advmod |
nonetheless,suggest |
R4064 |
T5933 |
T5934 |
mark |
that,involves |
R4065 |
T5934 |
T5907 |
ccomp |
involves,suggest |
R4066 |
T5935 |
T5936 |
det |
the,phenotype |
R4067 |
T5936 |
T5934 |
nsubj |
phenotype,involves |
R4068 |
T5937 |
T5936 |
amod |
combined,phenotype |
R4069 |
T5938 |
T5936 |
compound |
XPTTD,phenotype |
R4070 |
T5939 |
T5936 |
prep |
in,phenotype |
R4071 |
T5940 |
T5941 |
det |
this,patient |
R4072 |
T5941 |
T5939 |
pobj |
patient,in |
R4073 |
T5942 |
T5943 |
amod |
phenotypic,contributions |
R4074 |
T5943 |
T5934 |
dobj |
contributions,involves |
R4075 |
T5944 |
T5943 |
prep |
from,contributions |
R4076 |
T5945 |
T5946 |
det |
both,alleles |
R4077 |
T5946 |
T5944 |
pobj |
alleles,from |
R4078 |
T5947 |
T5907 |
punct |
.,suggest |
R4079 |
T5949 |
T5950 |
advcl |
Taken,suggest |
R4080 |
T5951 |
T5949 |
advmod |
together,Taken |
R4081 |
T5952 |
T5950 |
punct |
", ",suggest |
R4082 |
T5953 |
T5954 |
det |
these,data |
R4083 |
T5954 |
T5950 |
nsubj |
data,suggest |
R4084 |
T5955 |
T5956 |
det |
a,shift |
R4085 |
T5956 |
T5950 |
dobj |
shift,suggest |
R4086 |
T5957 |
T5956 |
prep |
to,shift |
R4087 |
T5958 |
T5959 |
det |
a,paradigm |
R4088 |
T5959 |
T5957 |
pobj |
paradigm,to |
R4089 |
T5960 |
T5959 |
amod |
biallelic,paradigm |
R4090 |
T5961 |
T5959 |
prep |
for,paradigm |
R4091 |
T5962 |
T5963 |
nmod |
compound,patients |
R4092 |
T5963 |
T5961 |
pobj |
patients,for |
R4093 |
T5964 |
T5963 |
amod |
heterozygous,patients |
R4094 |
T5965 |
T5963 |
prep |
in,patients |
R4095 |
T5966 |
T5967 |
compound |
XP,D |
R4096 |
T5967 |
T5965 |
pobj |
D,in |
R4097 |
T5968 |
T5967 |
compound |
complementation,D |
R4098 |
T5969 |
T5967 |
compound |
group,D |
R4099 |
T5970 |
T5950 |
punct |
.,suggest |