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Id Subject Object Predicate Lexical cue
T2791 0-1610 sentence denotes Figure 3 Rescue of TTD-Associated Segmental Progeroid Features in Compound Heterozygous Xpd TTD/†XPCS Mice (A) Photographs of 20-mo-old wt, compound heterozygous XpdTTD/†XPCS, and homozygous XpdTTD/TTD mice. Note the extreme cachexia (lack of subcutaneous fat) in the XpdTTD/TTD mouse and the absence of this phenotype in wt and XpdTTD/†XPCS mice. (B) Radiographs of 20-mo-old male wt, XpdTTD/†XPCS, and XpdTTD/TTD mice. Ageing XpdTTD/TTD mice develop kyphosis (curvature of the spinal column) and reduction of bone mineral density as shown in the 6–8 segment of the tail vertebrae counted from the pelvis (see close-up at right). Note the absence of these features in the XpdTTD / † XPCS mouse. (C) Quantification of relative bone mineral density of tail vertebrae from 20-mo-old male wt (n = 3), XpdTTD/†XPCS (n = 4), and XpdTTD/TTD (n = 3) mice. The p-values indicate the significance of the difference relative to XpdTTD/TTD. Error bars indicate SEM. (D) Body weight curves as a function of time. Note that the age-dependent cachexia observed in XpdTTD/TTD mice was rescued in both male and female XpdTTD / †XPCS mice. Significant differences between wt and XpdTTD/TTD but not between wt and XpdTTD/†XPCS mice were observed at 9 and 18 mo of age as indicated by asterisks. Error bars indicate SEM. Table 2 Pleiotropic Xpd Biallelic Effects in Mice and Cells To determine whether the homozygous lethal Xpd†XPCS allele was unique in its ability to ameliorate symptoms associated with the XpdTTD allele, we generated compound heterozygous XpdTTD/†XP mice by crossing the corresponding heterozygous animals.
T8041 11-17 NN denotes Rescue
T8042 18-20 IN denotes of
T8043 21-24 NN denotes TTD
T8045 24-25 HYPH denotes -
T8044 25-35 JJ denotes Associated
T8047 36-45 JJ denotes Segmental
T8048 46-55 JJ denotes Progeroid
T8046 56-64 NNS denotes Features
T8049 65-67 IN denotes in
T8050 68-76 JJ denotes Compound
T8052 77-89 JJ denotes Heterozygous
T8053 90-97 NN denotes Xpd TTD
T8055 97-98 HYPH denotes /
T8054 98-103 NN denotes †XPCS
T8051 104-108 NNS denotes Mice
T8056 108-209 sentence denotes (A) Photographs of 20-mo-old wt, compound heterozygous XpdTTD/†XPCS, and homozygous XpdTTD/TTD mice.
T8057 109-110 -LRB- denotes (
T8058 110-111 LS denotes A
T8060 111-112 -RRB- denotes )
T8059 113-124 NNS denotes Photographs
T8061 125-127 IN denotes of
T8062 128-130 CD denotes 20
T8064 130-131 HYPH denotes -
T8063 131-133 NN denotes mo
T8066 133-134 HYPH denotes -
T8065 134-137 JJ denotes old
T8068 138-140 NN denotes wt
T8069 140-142 , denotes ,
T8070 142-150 JJ denotes compound
T8072 151-163 JJ denotes heterozygous
T8073 164-170 NN denotes XpdTTD
T8074 170-171 HYPH denotes /
T8071 171-176 NN denotes †XPCS
T8075 176-178 , denotes ,
T8076 178-181 CC denotes and
T8077 182-192 JJ denotes homozygous
T8079 193-199 NN denotes XpdTTD
T8080 199-200 HYPH denotes /
T8078 200-203 NN denotes TTD
T8067 204-208 NNS denotes mice
T8081 208-209 . denotes .
T8082 209-349 sentence denotes Note the extreme cachexia (lack of subcutaneous fat) in the XpdTTD/TTD mouse and the absence of this phenotype in wt and XpdTTD/†XPCS mice.
T8083 210-214 VB denotes Note
T8084 215-218 DT denotes the
T8086 219-226 JJ denotes extreme
T8085 227-235 NN denotes cachexia
T8087 236-237 -LRB- denotes (
T8088 237-241 NN denotes lack
T8089 242-244 IN denotes of
T8090 245-257 JJ denotes subcutaneous
T8091 258-261 NN denotes fat
T8092 261-262 -RRB- denotes )
T8093 263-265 IN denotes in
T8094 266-269 DT denotes the
T8096 270-276 NN denotes XpdTTD
T8098 276-277 HYPH denotes /
T8097 277-280 NN denotes TTD
T8095 281-286 NN denotes mouse
T8099 287-290 CC denotes and
T8100 291-294 DT denotes the
T8101 295-302 NN denotes absence
T8102 303-305 IN denotes of
T8103 306-310 DT denotes this
T8104 311-320 NN denotes phenotype
T8105 321-323 IN denotes in
T8106 324-326 NN denotes wt
T8108 327-330 CC denotes and
T8109 331-337 NN denotes XpdTTD
T8111 337-338 HYPH denotes /
T8110 338-343 NN denotes †XPCS
T8107 344-348 NNS denotes mice
T8112 348-349 . denotes .
T8113 349-422 sentence denotes (B) Radiographs of 20-mo-old male wt, XpdTTD/†XPCS, and XpdTTD/TTD mice.
T8114 350-351 -LRB- denotes (
T8115 351-352 LS denotes B
T8117 352-353 -RRB- denotes )
T8116 354-365 NNS denotes Radiographs
T8118 366-368 IN denotes of
T8119 369-371 CD denotes 20
T8121 371-372 HYPH denotes -
T8120 372-374 NN denotes mo
T8123 374-375 HYPH denotes -
T8122 375-378 JJ denotes old
T8125 379-383 JJ denotes male
T8126 384-386 NN denotes wt
T8127 386-388 , denotes ,
T8128 388-394 NN denotes XpdTTD
T8130 394-395 HYPH denotes /
T8129 395-400 NN denotes †XPCS
T8131 400-402 , denotes ,
T8132 402-405 CC denotes and
T8133 406-412 NN denotes XpdTTD
T8135 412-413 HYPH denotes /
T8134 413-416 NN denotes TTD
T8124 417-421 NNS denotes mice
T8136 421-422 . denotes .
T8137 422-632 sentence denotes Ageing XpdTTD/TTD mice develop kyphosis (curvature of the spinal column) and reduction of bone mineral density as shown in the 6–8 segment of the tail vertebrae counted from the pelvis (see close-up at right).
T8138 423-429 VBG denotes Ageing
T8140 430-436 NN denotes XpdTTD
T8142 436-437 HYPH denotes /
T8141 437-440 NN denotes TTD
T8139 441-445 NNS denotes mice
T8143 446-453 VBP denotes develop
T8144 454-462 NN denotes kyphosis
T8145 463-464 -LRB- denotes (
T8146 464-473 NN denotes curvature
T8147 474-476 IN denotes of
T8148 477-480 DT denotes the
T8150 481-487 JJ denotes spinal
T8149 488-494 NN denotes column
T8151 494-495 -RRB- denotes )
T8152 496-499 CC denotes and
T8153 500-509 NN denotes reduction
T8154 510-512 IN denotes of
T8155 513-517 NN denotes bone
T8156 518-525 NN denotes mineral
T8157 526-533 NN denotes density
T8158 534-536 IN denotes as
T8159 537-542 VBN denotes shown
T8160 543-545 IN denotes in
T8161 546-549 DT denotes the
T8163 550-551 CD denotes 6
T8165 551-552 SYM denotes –
T8164 552-553 CD denotes 8
T8162 554-561 NN denotes segment
T8166 562-564 IN denotes of
T8167 565-568 DT denotes the
T8169 569-573 NN denotes tail
T8168 574-583 NNS denotes vertebrae
T8170 584-591 VBN denotes counted
T8171 592-596 IN denotes from
T8172 597-600 DT denotes the
T8173 601-607 NN denotes pelvis
T8174 608-609 -LRB- denotes (
T8175 609-612 VB denotes see
T8176 613-618 JJ denotes close
T8177 618-619 HYPH denotes -
T8178 619-621 RP denotes up
T8179 622-624 IN denotes at
T8180 625-630 NN denotes right
T8181 630-631 -RRB- denotes )
T8182 631-632 . denotes .
T8183 632-697 sentence denotes Note the absence of these features in the XpdTTD / † XPCS mouse.
T8184 633-637 VB denotes Note
T8185 638-641 DT denotes the
T8186 642-649 NN denotes absence
T8187 650-652 IN denotes of
T8188 653-658 DT denotes these
T8189 659-667 NNS denotes features
T8190 668-670 IN denotes in
T8191 671-674 DT denotes the
T8193 675-682 NN denotes XpdTTD 
T8195 682-683 HYPH denotes /
T8194 683-690 NN denotes  † XPCS
T8192 691-696 NN denotes mouse
T8196 696-697 . denotes .
T8197 697-850 sentence denotes (C) Quantification of relative bone mineral density of tail vertebrae from 20-mo-old male wt (n = 3), XpdTTD/†XPCS (n = 4), and XpdTTD/TTD (n = 3) mice.
T8198 698-699 -LRB- denotes (
T8199 699-700 LS denotes C
T8201 700-701 -RRB- denotes )
T8200 702-716 NN denotes Quantification
T8202 717-719 IN denotes of
T8203 720-728 JJ denotes relative
T8205 729-733 NN denotes bone
T8206 734-741 NN denotes mineral
T8204 742-749 NN denotes density
T8207 750-752 IN denotes of
T8208 753-757 NN denotes tail
T8209 758-767 NNS denotes vertebrae
T8210 768-772 IN denotes from
T8211 773-775 CD denotes 20
T8213 775-776 HYPH denotes -
T8212 776-778 NN denotes mo
T8215 778-779 HYPH denotes -
T8214 779-782 JJ denotes old
T8217 783-787 JJ denotes male
T8218 788-790 NN denotes wt
T8219 791-792 -LRB- denotes (
T8221 792-793 NN denotes n
T8222 794-795 SYM denotes =
T8220 796-797 CD denotes 3
T8223 797-798 -RRB- denotes )
T8224 798-800 , denotes ,
T8225 800-806 NN denotes XpdTTD
T8227 806-807 HYPH denotes /
T8226 807-812 NN denotes †XPCS
T8228 813-814 -LRB- denotes (
T8230 814-815 NN denotes n
T8231 816-817 SYM denotes =
T8229 818-819 CD denotes 4
T8232 819-820 -RRB- denotes )
T8233 820-822 , denotes ,
T8234 822-825 CC denotes and
T8235 826-832 NN denotes XpdTTD
T8237 832-833 HYPH denotes /
T8236 833-836 NN denotes TTD
T8238 837-838 -LRB- denotes (
T8240 838-839 NN denotes n
T8241 840-841 SYM denotes =
T8239 842-843 CD denotes 3
T8242 843-844 -RRB- denotes )
T8216 845-849 NNS denotes mice
T8243 849-850 . denotes .
T8244 850-931 sentence denotes The p-values indicate the significance of the difference relative to XpdTTD/TTD.
T8245 851-854 DT denotes The
T8247 855-856 NN denotes p
T8248 856-857 HYPH denotes -
T8246 857-863 NNS denotes values
T8249 864-872 VBP denotes indicate
T8250 873-876 DT denotes the
T8251 877-889 NN denotes significance
T8252 890-892 IN denotes of
T8253 893-896 DT denotes the
T8254 897-907 NN denotes difference
T8255 908-916 JJ denotes relative
T8256 917-919 IN denotes to
T8257 920-926 NN denotes XpdTTD
T8259 926-927 HYPH denotes /
T8258 927-930 NN denotes TTD
T8260 930-931 . denotes .
T8261 931-956 sentence denotes Error bars indicate SEM.
T8262 932-937 NN denotes Error
T8263 938-942 NNS denotes bars
T8264 943-951 VBP denotes indicate
T8265 952-955 NN denotes SEM
T8266 955-956 . denotes .
T8267 956-1002 sentence denotes (D) Body weight curves as a function of time.
T8268 957-958 -LRB- denotes (
T8269 958-959 LS denotes D
T8271 959-960 -RRB- denotes )
T8272 961-965 NN denotes Body
T8273 966-972 NN denotes weight
T8270 973-979 NNS denotes curves
T8274 980-982 IN denotes as
T8275 983-984 DT denotes a
T8276 985-993 NN denotes function
T8277 994-996 IN denotes of
T8278 997-1001 NN denotes time
T8279 1001-1002 . denotes .
T8280 1002-1124 sentence denotes Note that the age-dependent cachexia observed in XpdTTD/TTD mice was rescued in both male and female XpdTTD / †XPCS mice.
T8281 1003-1007 VB denotes Note
T8282 1008-1012 IN denotes that
T8284 1013-1016 DT denotes the
T8286 1017-1020 NN denotes age
T8288 1020-1021 HYPH denotes -
T8287 1021-1030 JJ denotes dependent
T8285 1031-1039 NN denotes cachexia
T8289 1040-1048 VBN denotes observed
T8290 1049-1051 IN denotes in
T8291 1052-1058 NN denotes XpdTTD
T8293 1058-1059 HYPH denotes /
T8292 1059-1062 NN denotes TTD
T8294 1063-1067 NNS denotes mice
T8295 1068-1071 VBD denotes was
T8283 1072-1079 VBN denotes rescued
T8296 1080-1082 IN denotes in
T8297 1083-1087 CC denotes both
T8298 1088-1092 JJ denotes male
T8300 1093-1096 CC denotes and
T8301 1097-1103 JJ denotes female
T8302 1104-1111 NN denotes XpdTTD 
T8304 1111-1112 HYPH denotes /
T8303 1112-1118 NN denotes  †XPCS
T8299 1119-1123 NNS denotes mice
T8305 1123-1124 . denotes .
T8306 1124-1278 sentence denotes Significant differences between wt and XpdTTD/TTD but not between wt and XpdTTD/†XPCS mice were observed at 9 and 18 mo of age as indicated by asterisks.
T8307 1125-1136 JJ denotes Significant
T8308 1137-1148 NNS denotes differences
T8310 1149-1156 IN denotes between
T8311 1157-1159 NN denotes wt
T8312 1160-1163 CC denotes and
T8313 1164-1170 NN denotes XpdTTD
T8315 1170-1171 HYPH denotes /
T8314 1171-1174 NN denotes TTD
T8316 1175-1178 CC denotes but
T8317 1179-1182 RB denotes not
T8318 1183-1190 IN denotes between
T8319 1191-1193 NN denotes wt
T8321 1194-1197 CC denotes and
T8322 1198-1204 NN denotes XpdTTD
T8324 1204-1205 HYPH denotes /
T8323 1205-1210 NN denotes †XPCS
T8320 1211-1215 NNS denotes mice
T8325 1216-1220 VBD denotes were
T8309 1221-1229 VBN denotes observed
T8326 1230-1232 IN denotes at
T8327 1233-1234 CD denotes 9
T8329 1235-1238 CC denotes and
T8330 1239-1241 CD denotes 18
T8328 1242-1244 NNS denotes mo
T8331 1245-1247 IN denotes of
T8332 1248-1251 NN denotes age
T8333 1252-1254 IN denotes as
T8334 1255-1264 VBN denotes indicated
T8335 1265-1267 IN denotes by
T8336 1268-1277 NNS denotes asterisks
T8337 1277-1278 . denotes .
T8338 1278-1303 sentence denotes Error bars indicate SEM.
T8339 1279-1284 NN denotes Error
T8340 1285-1289 NNS denotes bars
T8341 1290-1298 VBP denotes indicate
T8342 1299-1302 NN denotes SEM
T8343 1302-1303 . denotes .
T9241 1313-1324 JJ denotes Pleiotropic
T9243 1325-1328 NN denotes Xpd
T9244 1329-1338 JJ denotes Biallelic
T9242 1339-1346 NNS denotes Effects
T9245 1347-1349 IN denotes in
T9246 1350-1354 NNS denotes Mice
T9247 1355-1358 CC denotes and
T9248 1359-1364 NNS denotes Cells
T2792 1365-1367 TO denotes To
T2793 1368-1377 VB denotes determine
T2795 1378-1385 IN denotes whether
T2797 1386-1389 DT denotes the
T2799 1390-1400 JJ denotes homozygous
T2800 1401-1407 JJ denotes lethal
T2801 1408-1416 NN denotes Xpd†XPCS
T2798 1417-1423 NN denotes allele
T2796 1424-1427 VBD denotes was
T2802 1428-1434 JJ denotes unique
T2803 1435-1437 IN denotes in
T2804 1438-1441 PRP$ denotes its
T2805 1442-1449 NN denotes ability
T2806 1450-1452 TO denotes to
T2807 1453-1463 VB denotes ameliorate
T2808 1464-1472 NNS denotes symptoms
T2809 1473-1483 VBN denotes associated
T2810 1484-1488 IN denotes with
T2811 1489-1492 DT denotes the
T2813 1493-1499 NN denotes XpdTTD
T2812 1500-1506 NN denotes allele
T2814 1506-1508 , denotes ,
T2815 1508-1510 PRP denotes we
T2794 1511-1520 VBD denotes generated
T2816 1521-1529 NN denotes compound
T2818 1530-1542 JJ denotes heterozygous
T2819 1543-1549 NN denotes XpdTTD
T2821 1549-1550 HYPH denotes /
T2820 1550-1553 NN denotes †XP
T2817 1554-1558 NNS denotes mice
T2822 1559-1561 IN denotes by
T2823 1562-1570 VBG denotes crossing
T2824 1571-1574 DT denotes the
T2826 1575-1588 VBG denotes corresponding
T2827 1589-1601 JJ denotes heterozygous
T2825 1602-1609 NNS denotes animals
T2828 1609-1610 . denotes .
R1910 T2792 T2793 aux To,determine
R1911 T2793 T2794 advcl determine,generated
R1912 T2795 T2796 mark whether,was
R1913 T2796 T2793 ccomp was,determine
R1914 T2797 T2798 det the,allele
R1915 T2798 T2796 nsubj allele,was
R1916 T2799 T2798 amod homozygous,allele
R1917 T2800 T2798 amod lethal,allele
R1918 T2801 T2798 compound Xpd†XPCS,allele
R1919 T2802 T2796 acomp unique,was
R1920 T2803 T2802 prep in,unique
R1921 T2804 T2805 poss its,ability
R1922 T2805 T2803 pobj ability,in
R1923 T2806 T2807 aux to,ameliorate
R1924 T2807 T2805 acl ameliorate,ability
R1925 T2808 T2807 dobj symptoms,ameliorate
R1926 T2809 T2808 acl associated,symptoms
R1927 T2810 T2809 prep with,associated
R1928 T2811 T2812 det the,allele
R1929 T2812 T2810 pobj allele,with
R1930 T2813 T2812 compound XpdTTD,allele
R1931 T2814 T2794 punct ", ",generated
R1932 T2815 T2794 nsubj we,generated
R1933 T2816 T2817 nmod compound,mice
R1934 T2817 T2794 dobj mice,generated
R1935 T2818 T2817 amod heterozygous,mice
R1936 T2819 T2820 compound XpdTTD,†XP
R1937 T2820 T2817 compound †XP,mice
R1938 T2821 T2820 punct /,†XP
R1939 T2822 T2794 prep by,generated
R1940 T2823 T2822 pcomp crossing,by
R1941 T2824 T2825 det the,animals
R1942 T2825 T2823 dobj animals,crossing
R1943 T2826 T2825 amod corresponding,animals
R1944 T2827 T2825 amod heterozygous,animals
R1945 T2828 T2794 punct .,generated
R5429 T8042 T8041 prep of,Rescue
R5430 T8043 T8044 npadvmod TTD,Associated
R5431 T8044 T8046 amod Associated,Features
R5432 T8045 T8044 punct -,Associated
R5433 T8046 T8042 pobj Features,of
R5434 T8047 T8046 amod Segmental,Features
R5435 T8048 T8046 amod Progeroid,Features
R5436 T8049 T8046 prep in,Features
R5437 T8050 T8051 amod Compound,Mice
R5438 T8051 T8049 pobj Mice,in
R5439 T8052 T8051 amod Heterozygous,Mice
R5440 T8053 T8054 compound Xpd TTD,†XPCS
R5441 T8054 T8051 compound †XPCS,Mice
R5442 T8055 T8054 punct /,†XPCS
R5443 T8057 T8058 punct (,A
R5444 T8058 T8059 meta A,Photographs
R5445 T8060 T8058 punct ),A
R5446 T8061 T8059 prep of,Photographs
R5447 T8062 T8063 nummod 20,mo
R5448 T8063 T8065 npadvmod mo,old
R5449 T8064 T8063 punct -,mo
R5450 T8065 T8067 amod old,mice
R5451 T8066 T8065 punct -,old
R5452 T8067 T8061 pobj mice,of
R5453 T8068 T8067 nmod wt,mice
R5454 T8069 T8068 punct ", ",wt
R5455 T8070 T8071 amod compound,†XPCS
R5456 T8071 T8068 conj †XPCS,wt
R5457 T8072 T8071 amod heterozygous,†XPCS
R5458 T8073 T8071 compound XpdTTD,†XPCS
R5459 T8074 T8071 punct /,†XPCS
R5460 T8075 T8071 punct ", ",†XPCS
R5461 T8076 T8071 cc and,†XPCS
R5462 T8077 T8078 amod homozygous,TTD
R5463 T8078 T8071 conj TTD,†XPCS
R5464 T8079 T8078 compound XpdTTD,TTD
R5465 T8080 T8078 punct /,TTD
R5466 T8081 T8059 punct .,Photographs
R5467 T8084 T8085 det the,cachexia
R5468 T8085 T8083 dobj cachexia,Note
R5469 T8086 T8085 amod extreme,cachexia
R5470 T8087 T8085 punct (,cachexia
R5471 T8088 T8085 appos lack,cachexia
R5472 T8089 T8088 prep of,lack
R5473 T8090 T8091 amod subcutaneous,fat
R5474 T8091 T8089 pobj fat,of
R5475 T8092 T8085 punct ),cachexia
R5476 T8093 T8085 prep in,cachexia
R5477 T8094 T8095 det the,mouse
R5478 T8095 T8093 pobj mouse,in
R5479 T8096 T8097 compound XpdTTD,TTD
R5480 T8097 T8095 compound TTD,mouse
R5481 T8098 T8097 punct /,TTD
R5482 T8099 T8083 cc and,Note
R5483 T8100 T8101 det the,absence
R5484 T8101 T8083 conj absence,Note
R5485 T8102 T8101 prep of,absence
R5486 T8103 T8104 det this,phenotype
R5487 T8104 T8102 pobj phenotype,of
R5488 T8105 T8101 prep in,absence
R5489 T8106 T8107 nmod wt,mice
R5490 T8107 T8105 pobj mice,in
R5491 T8108 T8106 cc and,wt
R5492 T8109 T8110 compound XpdTTD,†XPCS
R5493 T8110 T8106 conj †XPCS,wt
R5494 T8111 T8110 punct /,†XPCS
R5495 T8112 T8083 punct .,Note
R5496 T8114 T8115 punct (,B
R5497 T8115 T8116 meta B,Radiographs
R5498 T8117 T8115 punct ),B
R5499 T8118 T8116 prep of,Radiographs
R5500 T8119 T8120 nummod 20,mo
R5501 T8120 T8122 npadvmod mo,old
R5502 T8121 T8120 punct -,mo
R5503 T8122 T8124 amod old,mice
R5504 T8123 T8122 punct -,old
R5505 T8124 T8118 pobj mice,of
R5506 T8125 T8124 amod male,mice
R5507 T8126 T8124 nmod wt,mice
R5508 T8127 T8126 punct ", ",wt
R5509 T8128 T8129 compound XpdTTD,†XPCS
R5510 T8129 T8126 conj †XPCS,wt
R5511 T8130 T8129 punct /,†XPCS
R5512 T8131 T8129 punct ", ",†XPCS
R5513 T8132 T8129 cc and,†XPCS
R5514 T8133 T8134 compound XpdTTD,TTD
R5515 T8134 T8129 conj TTD,†XPCS
R5516 T8135 T8134 punct /,TTD
R5517 T8136 T8116 punct .,Radiographs
R5518 T8138 T8139 amod Ageing,mice
R5519 T8139 T8143 nsubj mice,develop
R5520 T8140 T8141 compound XpdTTD,TTD
R5521 T8141 T8139 compound TTD,mice
R5522 T8142 T8141 punct /,TTD
R5523 T8144 T8143 dobj kyphosis,develop
R5524 T8145 T8144 punct (,kyphosis
R5525 T8146 T8144 appos curvature,kyphosis
R5526 T8147 T8146 prep of,curvature
R5527 T8148 T8149 det the,column
R5528 T8149 T8147 pobj column,of
R5529 T8150 T8149 amod spinal,column
R5530 T8151 T8144 punct ),kyphosis
R5531 T8152 T8144 cc and,kyphosis
R5532 T8153 T8144 conj reduction,kyphosis
R5533 T8154 T8153 prep of,reduction
R5534 T8155 T8156 compound bone,mineral
R5535 T8156 T8157 compound mineral,density
R5536 T8157 T8154 pobj density,of
R5537 T8158 T8159 mark as,shown
R5538 T8159 T8143 advcl shown,develop
R5539 T8160 T8159 prep in,shown
R5540 T8161 T8162 det the,segment
R5541 T8162 T8160 pobj segment,in
R5542 T8163 T8164 quantmod 6,8
R5543 T8164 T8162 nummod 8,segment
R5544 T8165 T8164 punct –,8
R5545 T8166 T8162 prep of,segment
R5546 T8167 T8168 det the,vertebrae
R5547 T8168 T8166 pobj vertebrae,of
R5548 T8169 T8168 compound tail,vertebrae
R5549 T8170 T8162 acl counted,segment
R5550 T8171 T8170 prep from,counted
R5551 T8172 T8173 det the,pelvis
R5552 T8173 T8171 pobj pelvis,from
R5553 T8174 T8175 punct (,see
R5554 T8175 T8143 parataxis see,develop
R5555 T8176 T8175 dobj close,see
R5556 T8177 T8176 punct -,close
R5557 T8178 T8176 prt up,close
R5558 T8179 T8176 prep at,close
R5559 T8180 T8179 pobj right,at
R5560 T8181 T8175 punct ),see
R5561 T8182 T8143 punct .,develop
R5562 T8185 T8186 det the,absence
R5563 T8186 T8184 dobj absence,Note
R5564 T8187 T8186 prep of,absence
R5565 T8188 T8189 det these,features
R5566 T8189 T8187 pobj features,of
R5567 T8190 T8186 prep in,absence
R5568 T8191 T8192 det the,mouse
R5569 T8192 T8190 pobj mouse,in
R5570 T8193 T8194 compound XpdTTD , † XPCS
R5571 T8194 T8192 compound  † XPCS,mouse
R5572 T8195 T8194 punct /, † XPCS
R5573 T8196 T8184 punct .,Note
R5574 T8198 T8199 punct (,C
R5575 T8199 T8200 meta C,Quantification
R5576 T8201 T8199 punct ),C
R5577 T8202 T8200 prep of,Quantification
R5578 T8203 T8204 amod relative,density
R5579 T8204 T8202 pobj density,of
R5580 T8205 T8206 compound bone,mineral
R5581 T8206 T8204 compound mineral,density
R5582 T8207 T8204 prep of,density
R5583 T8208 T8209 compound tail,vertebrae
R5584 T8209 T8207 pobj vertebrae,of
R5585 T8210 T8209 prep from,vertebrae
R5586 T8211 T8212 nummod 20,mo
R5587 T8212 T8214 npadvmod mo,old
R5588 T8213 T8212 punct -,mo
R5589 T8214 T8216 amod old,mice
R5590 T8215 T8214 punct -,old
R5591 T8216 T8210 pobj mice,from
R5592 T8217 T8216 amod male,mice
R5593 T8218 T8216 nmod wt,mice
R5594 T8219 T8220 punct (,3
R5595 T8220 T8218 parataxis 3,wt
R5596 T8221 T8220 nsubj n,3
R5597 T8222 T8220 punct =,3
R5598 T8223 T8220 punct ),3
R5599 T8224 T8218 punct ", ",wt
R5600 T8225 T8226 compound XpdTTD,†XPCS
R5601 T8226 T8218 conj †XPCS,wt
R5602 T8227 T8226 punct /,†XPCS
R5603 T8228 T8229 punct (,4
R5604 T8229 T8226 parataxis 4,†XPCS
R5605 T8230 T8229 nsubj n,4
R5606 T8231 T8229 punct =,4
R5607 T8232 T8229 punct ),4
R5608 T8233 T8226 punct ", ",†XPCS
R5609 T8234 T8226 cc and,†XPCS
R5610 T8235 T8236 compound XpdTTD,TTD
R5611 T8236 T8226 conj TTD,†XPCS
R5612 T8237 T8236 punct /,TTD
R5613 T8238 T8239 punct (,3
R5614 T8239 T8236 parataxis 3,TTD
R5615 T8240 T8239 nsubj n,3
R5616 T8241 T8239 punct =,3
R5617 T8242 T8239 punct ),3
R5618 T8243 T8200 punct .,Quantification
R5619 T8245 T8246 det The,values
R5620 T8246 T8249 nsubj values,indicate
R5621 T8247 T8246 compound p,values
R5622 T8248 T8246 punct -,values
R5623 T8250 T8251 det the,significance
R5624 T8251 T8249 dobj significance,indicate
R5625 T8252 T8251 prep of,significance
R5626 T8253 T8254 det the,difference
R5627 T8254 T8252 pobj difference,of
R5628 T8255 T8249 advcl relative,indicate
R5629 T8256 T8255 prep to,relative
R5630 T8257 T8258 compound XpdTTD,TTD
R5631 T8258 T8256 pobj TTD,to
R5632 T8259 T8258 punct /,TTD
R5633 T8260 T8249 punct .,indicate
R5634 T8262 T8263 compound Error,bars
R5635 T8263 T8264 nsubj bars,indicate
R5636 T8265 T8264 dobj SEM,indicate
R5637 T8266 T8264 punct .,indicate
R5638 T8268 T8269 punct (,D
R5639 T8269 T8270 meta D,curves
R5640 T8271 T8269 punct ),D
R5641 T8272 T8273 compound Body,weight
R5642 T8273 T8270 compound weight,curves
R5643 T8274 T8270 prep as,curves
R5644 T8275 T8276 det a,function
R5645 T8276 T8274 pobj function,as
R5646 T8277 T8276 prep of,function
R5647 T8278 T8277 pobj time,of
R5648 T8279 T8270 punct .,curves
R5649 T8282 T8283 mark that,rescued
R5650 T8283 T8281 ccomp rescued,Note
R5651 T8284 T8285 det the,cachexia
R5652 T8285 T8283 nsubjpass cachexia,rescued
R5653 T8286 T8287 npadvmod age,dependent
R5654 T8287 T8285 amod dependent,cachexia
R5655 T8288 T8287 punct -,dependent
R5656 T8289 T8285 acl observed,cachexia
R5657 T8290 T8289 prep in,observed
R5658 T8291 T8292 compound XpdTTD,TTD
R5659 T8292 T8294 compound TTD,mice
R5660 T8293 T8292 punct /,TTD
R5661 T8294 T8290 pobj mice,in
R5662 T8295 T8283 auxpass was,rescued
R5663 T8296 T8283 prep in,rescued
R5664 T8297 T8298 preconj both,male
R5665 T8298 T8299 nmod male,mice
R5666 T8299 T8296 pobj mice,in
R5667 T8300 T8298 cc and,male
R5668 T8301 T8298 conj female,male
R5669 T8302 T8303 compound XpdTTD , †XPCS
R5670 T8303 T8299 compound  †XPCS,mice
R5671 T8304 T8303 punct /, †XPCS
R5672 T8305 T8281 punct .,Note
R5673 T8307 T8308 amod Significant,differences
R5674 T8308 T8309 nsubjpass differences,observed
R5675 T8310 T8308 prep between,differences
R5676 T8311 T8310 pobj wt,between
R5677 T8312 T8311 cc and,wt
R5678 T8313 T8314 compound XpdTTD,TTD
R5679 T8314 T8311 conj TTD,wt
R5680 T8315 T8314 punct /,TTD
R5681 T8316 T8310 cc but,between
R5682 T8317 T8316 neg not,but
R5683 T8318 T8310 conj between,between
R5684 T8319 T8320 nmod wt,mice
R5685 T8320 T8318 pobj mice,between
R5686 T8321 T8319 cc and,wt
R5687 T8322 T8323 compound XpdTTD,†XPCS
R5688 T8323 T8319 conj †XPCS,wt
R5689 T8324 T8323 punct /,†XPCS
R5690 T8325 T8309 auxpass were,observed
R5691 T8326 T8309 prep at,observed
R5692 T8327 T8328 nummod 9,mo
R5693 T8328 T8326 pobj mo,at
R5694 T8329 T8327 cc and,9
R5695 T8330 T8327 conj 18,9
R5696 T8331 T8328 prep of,mo
R5697 T8332 T8331 pobj age,of
R5698 T8333 T8334 mark as,indicated
R5699 T8334 T8309 advcl indicated,observed
R5700 T8335 T8334 agent by,indicated
R5701 T8336 T8335 pobj asterisks,by
R5702 T8337 T8309 punct .,observed
R5703 T8339 T8340 compound Error,bars
R5704 T8340 T8341 nsubj bars,indicate
R5705 T8342 T8341 dobj SEM,indicate
R5706 T8343 T8341 punct .,indicate
R6322 T9241 T9242 amod Pleiotropic,Effects
R6323 T9243 T9242 nmod Xpd,Effects
R6324 T9244 T9242 amod Biallelic,Effects
R6325 T9245 T9242 prep in,Effects
R6326 T9246 T9245 pobj Mice,in
R6327 T9247 T9246 cc and,Mice
R6328 T9248 T9246 conj Cells,Mice