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PMC:1584416 / 13860-14841 JSONTXT 5 Projects

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Id Subject Object Predicate Lexical cue
T2585 0-7 IN denotes Because
T2587 8-16 NNS denotes patients
T2588 17-21 IN denotes with
T2589 22-25 NN denotes TTD
T2590 25-27 , denotes ,
T2591 27-31 NN denotes XPCS
T2592 31-33 , denotes ,
T2593 33-36 CC denotes and
T2594 37-39 NN denotes CS
T2595 40-41 -LRB- denotes (
T2596 41-44 CC denotes but
T2597 45-48 RB denotes not
T2598 49-51 NN denotes XP
T2599 51-52 -RRB- denotes )
T2600 53-56 CC denotes and
T2601 57-60 DT denotes the
T2603 61-74 VBG denotes corresponding
T2604 75-80 NN denotes mouse
T2602 81-87 NNS denotes models
T2586 88-93 VBP denotes share
T2606 94-101 JJ denotes similar
T2608 102-113 VBN denotes accelerated
T2609 114-123 NN denotes progeroid
T2607 124-132 NNS denotes symptoms
T2610 133-134 -LRB- denotes [
T2612 134-136 CD denotes 12
T2613 136-137 , denotes ,
T2614 137-139 CD denotes 13
T2615 139-140 , denotes ,
T2616 140-142 CD denotes 15
T2617 142-143 , denotes ,
T2611 143-145 CD denotes 23
T2618 145-146 -RRB- denotes ]
T2619 146-148 , denotes ,
T2620 148-150 PRP denotes we
T2621 151-155 RB denotes next
T2605 156-165 VBD denotes addressed
T2622 166-172 JJ denotes ageing
T2624 172-173 HYPH denotes -
T2623 173-180 JJ denotes related
T2625 181-191 NNS denotes parameters
T2626 192-194 IN denotes in
T2627 195-203 JJ denotes compound
T2629 204-216 JJ denotes heterozygous
T2628 217-221 NNS denotes mice
T2630 222-223 -LRB- denotes (
T2631 223-229 NN denotes Figure
T2632 230-231 CD denotes 3
T2633 231-232 -RRB- denotes )
T2634 232-233 . denotes .
T2635 233-496 sentence denotes Whereas XpdTTD/TTD animals show reduced bone mineral density as an indication of the early onset of osteoporosis before ~14 mo of age [15], tail vertebrae from compound heterozygous XpdTTD/†XPCS mice were comparable to wt even at 20 mo of age (Figure 3B and 3C).
T2636 234-241 IN denotes Whereas
T2638 242-248 NN denotes XpdTTD
T2640 248-249 HYPH denotes /
T2639 249-252 NN denotes TTD
T2641 253-260 NNS denotes animals
T2637 261-265 VBP denotes show
T2643 266-273 VBN denotes reduced
T2645 274-278 NN denotes bone
T2646 279-286 NN denotes mineral
T2644 287-294 NN denotes density
T2647 295-297 IN denotes as
T2648 298-300 DT denotes an
T2649 301-311 NN denotes indication
T2650 312-314 IN denotes of
T2651 315-318 DT denotes the
T2653 319-324 JJ denotes early
T2652 325-330 NN denotes onset
T2654 331-333 IN denotes of
T2655 334-346 NN denotes osteoporosis
T2656 347-353 IN denotes before
T2657 354-355 SYM denotes ~
T2658 355-357 CD denotes 14
T2659 358-360 NNS denotes mo
T2660 361-363 IN denotes of
T2661 364-367 NN denotes age
T2662 368-369 -LRB- denotes [
T2663 369-371 CD denotes 15
T2664 371-372 -RRB- denotes ]
T2665 372-374 , denotes ,
T2666 374-378 NN denotes tail
T2667 379-388 NNS denotes vertebrae
T2668 389-393 IN denotes from
T2669 394-402 NN denotes compound
T2671 403-415 JJ denotes heterozygous
T2672 416-422 NN denotes XpdTTD
T2674 422-423 HYPH denotes /
T2673 423-428 NN denotes †XPCS
T2670 429-433 NNS denotes mice
T2642 434-438 VBD denotes were
T2675 439-449 JJ denotes comparable
T2676 450-452 IN denotes to
T2677 453-455 NN denotes wt
T2678 456-460 RB denotes even
T2679 461-463 IN denotes at
T2680 464-466 CD denotes 20
T2681 467-469 NNS denotes mo
T2682 470-472 IN denotes of
T2683 473-476 NN denotes age
T2684 477-478 -LRB- denotes (
T2686 478-484 NN denotes Figure
T2685 485-487 NN denotes 3B
T2687 488-491 CC denotes and
T2688 492-494 NN denotes 3C
T2689 494-495 -RRB- denotes )
T2690 495-496 . denotes .
T2691 496-668 sentence denotes Furthermore, whereas XpdTTD/TTD mice developed kyphosis earlier than wt animals (onset ~3 mo versus 12–20 mo), compound heterozygous XpdTTD/†XPCS mice did not (Figure 3B).
T2692 497-508 RB denotes Furthermore
T2694 508-510 , denotes ,
T2695 510-517 IN denotes whereas
T2697 518-524 NN denotes XpdTTD
T2699 524-525 HYPH denotes /
T2698 525-528 NN denotes TTD
T2700 529-533 NNS denotes mice
T2696 534-543 VBD denotes developed
T2701 544-552 NN denotes kyphosis
T2702 553-560 RBR denotes earlier
T2703 561-565 IN denotes than
T2704 566-568 NN denotes wt
T2705 569-576 NNS denotes animals
T2706 577-578 -LRB- denotes (
T2707 578-583 NN denotes onset
T2708 584-585 SYM denotes ~
T2709 585-586 CD denotes 3
T2710 587-589 NNS denotes mo
T2711 590-596 CC denotes versus
T2712 597-599 CD denotes 12
T2714 599-600 SYM denotes –
T2713 600-602 CD denotes 20
T2715 603-605 NNS denotes mo
T2716 605-606 -RRB- denotes )
T2717 606-608 , denotes ,
T2718 608-616 JJ denotes compound
T2720 617-629 JJ denotes heterozygous
T2721 630-636 NN denotes XpdTTD
T2723 636-637 HYPH denotes /
T2722 637-642 NN denotes †XPCS
T2719 643-647 NNS denotes mice
T2724 648-651 VBD denotes did
T2725 652-655 RB denotes not
T2726 656-657 -LRB- denotes (
T2727 657-663 NN denotes Figure
T2693 664-666 NN denotes 3B
T2728 666-667 -RRB- denotes )
T2729 667-668 . denotes .
T2730 668-880 sentence denotes Overall appearance and body weight curves revealed that TTD-associated age-related premature cachexia and lack of general fitness were fully rescued in compound heterozygous XpdTTD/†XPCS mice (Figure 3A and 3D).
T2731 669-676 JJ denotes Overall
T2732 677-687 NN denotes appearance
T2734 688-691 CC denotes and
T2735 692-696 NN denotes body
T2736 697-703 NN denotes weight
T2737 704-710 NNS denotes curves
T2733 711-719 VBD denotes revealed
T2738 720-724 IN denotes that
T2740 725-728 NN denotes TTD
T2742 728-729 HYPH denotes -
T2741 729-739 JJ denotes associated
T2744 740-743 NN denotes age
T2746 743-744 HYPH denotes -
T2745 744-751 JJ denotes related
T2747 752-761 JJ denotes premature
T2743 762-770 NN denotes cachexia
T2748 771-774 CC denotes and
T2749 775-779 NN denotes lack
T2750 780-782 IN denotes of
T2751 783-790 JJ denotes general
T2752 791-798 NN denotes fitness
T2753 799-803 VBD denotes were
T2754 804-809 RB denotes fully
T2739 810-817 VBN denotes rescued
T2755 818-820 IN denotes in
T2756 821-829 JJ denotes compound
T2758 830-842 JJ denotes heterozygous
T2759 843-849 NN denotes XpdTTD
T2761 849-850 HYPH denotes /
T2760 850-855 NN denotes †XPCS
T2757 856-860 NNS denotes mice
T2762 861-862 -LRB- denotes (
T2764 862-868 NN denotes Figure
T2763 869-871 NN denotes 3A
T2765 872-875 CC denotes and
T2766 876-878 NN denotes 3D
T2767 878-879 -RRB- denotes )
T2768 879-880 . denotes .
T2769 880-981 sentence denotes Finally, the life span of compound heterozygotes was extended relative to XpdTTD/TTD mice (Table 2).
T2770 881-888 RB denotes Finally
T2772 888-890 , denotes ,
T2773 890-893 DT denotes the
T2775 894-898 NN denotes life
T2774 899-903 NN denotes span
T2776 904-906 IN denotes of
T2777 907-915 JJ denotes compound
T2778 916-929 NNS denotes heterozygotes
T2779 930-933 VBD denotes was
T2771 934-942 VBN denotes extended
T2780 943-951 JJ denotes relative
T2781 952-954 IN denotes to
T2782 955-961 NN denotes XpdTTD
T2784 961-962 HYPH denotes /
T2783 962-965 NN denotes TTD
T2785 966-970 NNS denotes mice
T2786 971-972 -LRB- denotes (
T2787 972-977 NN denotes Table
T2788 978-979 CD denotes 2
T2789 979-980 -RRB- denotes )
T2790 980-981 . denotes .
R1713 T2585 T2586 mark Because,share
R1714 T2586 T2605 advcl share,addressed
R1715 T2587 T2586 nsubj patients,share
R1716 T2588 T2587 prep with,patients
R1717 T2589 T2588 pobj TTD,with
R1718 T2590 T2589 punct ", ",TTD
R1719 T2591 T2589 conj XPCS,TTD
R1720 T2592 T2591 punct ", ",XPCS
R1721 T2593 T2591 cc and,XPCS
R1722 T2594 T2591 conj CS,XPCS
R1723 T2595 T2589 punct (,TTD
R1724 T2596 T2589 cc but,TTD
R1725 T2597 T2596 neg not,but
R1726 T2598 T2589 conj XP,TTD
R1727 T2599 T2587 punct ),patients
R1728 T2600 T2587 cc and,patients
R1729 T2601 T2602 det the,models
R1730 T2602 T2587 conj models,patients
R1731 T2603 T2602 amod corresponding,models
R1732 T2604 T2602 compound mouse,models
R1733 T2606 T2607 amod similar,symptoms
R1734 T2607 T2586 dobj symptoms,share
R1735 T2608 T2607 amod accelerated,symptoms
R1736 T2609 T2607 compound progeroid,symptoms
R1737 T2610 T2611 punct [,23
R1738 T2611 T2586 parataxis 23,share
R1739 T2612 T2611 nummod 12,23
R1740 T2613 T2611 punct ",",23
R1741 T2614 T2611 nummod 13,23
R1742 T2615 T2611 punct ",",23
R1743 T2616 T2611 nummod 15,23
R1744 T2617 T2611 punct ",",23
R1745 T2618 T2611 punct ],23
R1746 T2619 T2605 punct ", ",addressed
R1747 T2620 T2605 nsubj we,addressed
R1748 T2621 T2605 advmod next,addressed
R1749 T2622 T2623 amod ageing,related
R1750 T2623 T2625 amod related,parameters
R1751 T2624 T2623 punct -,related
R1752 T2625 T2605 dobj parameters,addressed
R1753 T2626 T2625 prep in,parameters
R1754 T2627 T2628 amod compound,mice
R1755 T2628 T2626 pobj mice,in
R1756 T2629 T2628 amod heterozygous,mice
R1757 T2630 T2631 punct (,Figure
R1758 T2631 T2605 parataxis Figure,addressed
R1759 T2632 T2631 nummod 3,Figure
R1760 T2633 T2631 punct ),Figure
R1761 T2634 T2605 punct .,addressed
R1762 T2636 T2637 mark Whereas,show
R1763 T2637 T2642 advcl show,were
R1764 T2638 T2639 compound XpdTTD,TTD
R1765 T2639 T2641 compound TTD,animals
R1766 T2640 T2639 punct /,TTD
R1767 T2641 T2637 nsubj animals,show
R1768 T2643 T2644 amod reduced,density
R1769 T2644 T2637 dobj density,show
R1770 T2645 T2646 compound bone,mineral
R1771 T2646 T2644 compound mineral,density
R1772 T2647 T2637 prep as,show
R1773 T2648 T2649 det an,indication
R1774 T2649 T2647 pobj indication,as
R1775 T2650 T2649 prep of,indication
R1776 T2651 T2652 det the,onset
R1777 T2652 T2650 pobj onset,of
R1778 T2653 T2652 amod early,onset
R1779 T2654 T2652 prep of,onset
R1780 T2655 T2654 pobj osteoporosis,of
R1781 T2656 T2652 prep before,onset
R1782 T2657 T2658 punct ~,14
R1783 T2658 T2659 nummod 14,mo
R1784 T2659 T2656 pobj mo,before
R1785 T2660 T2659 prep of,mo
R1786 T2661 T2660 pobj age,of
R1787 T2662 T2663 punct [,15
R1788 T2663 T2637 parataxis 15,show
R1789 T2664 T2663 punct ],15
R1790 T2665 T2642 punct ", ",were
R1791 T2666 T2667 compound tail,vertebrae
R1792 T2667 T2642 nsubj vertebrae,were
R1793 T2668 T2667 prep from,vertebrae
R1794 T2669 T2670 nmod compound,mice
R1795 T2670 T2668 pobj mice,from
R1796 T2671 T2670 amod heterozygous,mice
R1797 T2672 T2673 compound XpdTTD,†XPCS
R1798 T2673 T2670 compound †XPCS,mice
R1799 T2674 T2673 punct /,†XPCS
R1800 T2675 T2642 acomp comparable,were
R1801 T2676 T2675 prep to,comparable
R1802 T2677 T2676 pobj wt,to
R1803 T2678 T2679 advmod even,at
R1804 T2679 T2642 prep at,were
R1805 T2680 T2681 nummod 20,mo
R1806 T2681 T2679 pobj mo,at
R1807 T2682 T2681 prep of,mo
R1808 T2683 T2682 pobj age,of
R1809 T2684 T2685 punct (,3B
R1810 T2685 T2642 parataxis 3B,were
R1811 T2686 T2685 compound Figure,3B
R1812 T2687 T2685 cc and,3B
R1813 T2688 T2685 conj 3C,3B
R1814 T2689 T2685 punct ),3B
R1815 T2690 T2642 punct .,were
R1816 T2692 T2693 advmod Furthermore,3B
R1817 T2694 T2693 punct ", ",3B
R1818 T2695 T2696 mark whereas,developed
R1819 T2696 T2693 advcl developed,3B
R1820 T2697 T2698 compound XpdTTD,TTD
R1821 T2698 T2700 compound TTD,mice
R1822 T2699 T2698 punct /,TTD
R1823 T2700 T2696 nsubj mice,developed
R1824 T2701 T2696 dobj kyphosis,developed
R1825 T2702 T2696 advmod earlier,developed
R1826 T2703 T2702 prep than,earlier
R1827 T2704 T2705 compound wt,animals
R1828 T2705 T2703 pobj animals,than
R1829 T2706 T2707 punct (,onset
R1830 T2707 T2702 parataxis onset,earlier
R1831 T2708 T2709 punct ~,3
R1832 T2709 T2710 nummod 3,mo
R1833 T2710 T2707 npadvmod mo,onset
R1834 T2711 T2710 cc versus,mo
R1835 T2712 T2713 quantmod 12,20
R1836 T2713 T2715 nummod 20,mo
R1837 T2714 T2713 punct –,20
R1838 T2715 T2710 conj mo,mo
R1839 T2716 T2707 punct ),onset
R1840 T2717 T2693 punct ", ",3B
R1841 T2718 T2719 amod compound,mice
R1842 T2719 T2693 nsubj mice,3B
R1843 T2720 T2719 amod heterozygous,mice
R1844 T2721 T2722 compound XpdTTD,†XPCS
R1845 T2722 T2719 compound †XPCS,mice
R1846 T2723 T2722 punct /,†XPCS
R1847 T2724 T2693 aux did,3B
R1848 T2725 T2693 neg not,3B
R1849 T2726 T2693 punct (,3B
R1850 T2727 T2693 compound Figure,3B
R1851 T2728 T2693 punct ),3B
R1852 T2729 T2693 punct .,3B
R1853 T2731 T2732 amod Overall,appearance
R1854 T2732 T2733 nsubj appearance,revealed
R1855 T2734 T2732 cc and,appearance
R1856 T2735 T2736 compound body,weight
R1857 T2736 T2737 compound weight,curves
R1858 T2737 T2732 conj curves,appearance
R1859 T2738 T2739 mark that,rescued
R1860 T2739 T2733 ccomp rescued,revealed
R1861 T2740 T2741 npadvmod TTD,associated
R1862 T2741 T2743 amod associated,cachexia
R1863 T2742 T2741 punct -,associated
R1864 T2743 T2739 nsubjpass cachexia,rescued
R1865 T2744 T2745 npadvmod age,related
R1866 T2745 T2743 amod related,cachexia
R1867 T2746 T2745 punct -,related
R1868 T2747 T2743 amod premature,cachexia
R1869 T2748 T2743 cc and,cachexia
R1870 T2749 T2743 conj lack,cachexia
R1871 T2750 T2749 prep of,lack
R1872 T2751 T2752 amod general,fitness
R1873 T2752 T2750 pobj fitness,of
R1874 T2753 T2739 auxpass were,rescued
R1875 T2754 T2739 advmod fully,rescued
R1876 T2755 T2739 prep in,rescued
R1877 T2756 T2757 amod compound,mice
R1878 T2757 T2755 pobj mice,in
R1879 T2758 T2757 amod heterozygous,mice
R1880 T2759 T2760 compound XpdTTD,†XPCS
R1881 T2760 T2757 compound †XPCS,mice
R1882 T2761 T2760 punct /,†XPCS
R1883 T2762 T2763 punct (,3A
R1884 T2763 T2733 parataxis 3A,revealed
R1885 T2764 T2763 compound Figure,3A
R1886 T2765 T2763 cc and,3A
R1887 T2766 T2763 conj 3D,3A
R1888 T2767 T2763 punct ),3A
R1889 T2768 T2733 punct .,revealed
R1890 T2770 T2771 advmod Finally,extended
R1891 T2772 T2771 punct ", ",extended
R1892 T2773 T2774 det the,span
R1893 T2774 T2771 nsubjpass span,extended
R1894 T2775 T2774 compound life,span
R1895 T2776 T2774 prep of,span
R1896 T2777 T2778 amod compound,heterozygotes
R1897 T2778 T2776 pobj heterozygotes,of
R1898 T2779 T2771 auxpass was,extended
R1899 T2780 T2771 advcl relative,extended
R1900 T2781 T2780 prep to,relative
R1901 T2782 T2783 compound XpdTTD,TTD
R1902 T2783 T2785 compound TTD,mice
R1903 T2784 T2783 punct /,TTD
R1904 T2785 T2781 pobj mice,to
R1905 T2786 T2787 punct (,Table
R1906 T2787 T2771 parataxis Table,extended
R1907 T2788 T2787 nummod 2,Table
R1908 T2789 T2787 punct ),Table
R1909 T2790 T2771 punct .,extended