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PMC:1540739 / 5013-5542 JSONTXT 5 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T3259 0-4 JJS denotes Most
T3261 5-9 NN denotes RMCE
T3260 10-21 NNS denotes experiments
T3263 22-26 VBP denotes have
T3264 27-31 VBN denotes been
T3262 32-41 VBN denotes performed
T3265 42-44 IN denotes at
T3266 45-51 JJ denotes random
T3267 52-57 NNS denotes sites
T3268 58-60 IN denotes in
T3269 61-68 JJ denotes somatic
T3270 69-73 NN denotes cell
T3271 74-79 NNS denotes lines
T3272 79-80 . denotes .
T3273 80-290 sentence denotes Only a few mutant mice generated by RMCE in ES cells have been reported, but the RMCE systematically introduced a selectable marker (15–17), or, when tested without an incoming marker, proved inefficient (12).
T3274 81-85 RB denotes Only
T3276 86-87 DT denotes a
T3277 88-91 JJ denotes few
T3278 92-98 JJ denotes mutant
T3275 99-103 NNS denotes mice
T3280 104-113 VBN denotes generated
T3281 114-116 IN denotes by
T3282 117-121 NN denotes RMCE
T3283 122-124 IN denotes in
T3284 125-127 NN denotes ES
T3285 128-133 NNS denotes cells
T3286 134-138 VBP denotes have
T3287 139-143 VBN denotes been
T3279 144-152 VBN denotes reported
T3288 152-154 , denotes ,
T3289 154-157 CC denotes but
T3290 158-161 DT denotes the
T3291 162-166 NN denotes RMCE
T3293 167-181 RB denotes systematically
T3292 182-192 VBD denotes introduced
T3294 193-194 DT denotes a
T3296 195-205 JJ denotes selectable
T3295 206-212 NN denotes marker
T3297 213-214 -LRB- denotes (
T3298 214-219 CD denotes 15–17
T3299 219-220 -RRB- denotes )
T3300 220-222 , denotes ,
T3301 222-224 CC denotes or
T3302 224-226 , denotes ,
T3303 226-230 WRB denotes when
T3304 231-237 VBN denotes tested
T3306 238-245 IN denotes without
T3307 246-248 DT denotes an
T3309 249-257 JJ denotes incoming
T3308 258-264 NN denotes marker
T3310 264-266 , denotes ,
T3305 266-272 VBD denotes proved
T3311 273-284 JJ denotes inefficient
T3312 285-286 -LRB- denotes (
T3313 286-288 CD denotes 12
T3314 288-289 -RRB- denotes )
T3315 289-290 . denotes .
T3316 290-338 sentence denotes A recent report disclosed an additional problem
T3317 291-292 DT denotes A
T3319 293-299 JJ denotes recent
T3318 300-306 NN denotes report
T3320 307-316 VBD denotes disclosed
T3321 317-319 DT denotes an
T3323 320-330 JJ denotes additional
T3322 331-338 NN denotes problem
T3324 338-340 : denotes :
T3326 338-529 sentence denotes : the Hygromycin–Thymidine Kinase fusion gene used most frequently for positive/negative selection in RMCE, leads to mouse sterility, so that exchanges can only be performed in ES cells (16).
T3327 340-343 DT denotes the
T3329 344-354 NN denotes Hygromycin
T3331 354-355 HYPH denotes –
T3330 355-364 NN denotes Thymidine
T3332 365-371 NN denotes Kinase
T3333 372-378 NN denotes fusion
T3328 379-383 NN denotes gene
T3334 384-388 VBN denotes used
T3335 389-393 RBS denotes most
T3336 394-404 RB denotes frequently
T3337 405-408 IN denotes for
T3338 409-417 JJ denotes positive
T3340 417-418 HYPH denotes /
T3339 418-426 JJ denotes negative
T3341 427-436 NN denotes selection
T3342 437-439 IN denotes in
T3343 440-444 NN denotes RMCE
T3344 444-446 , denotes ,
T3325 446-451 VBZ denotes leads
T3345 452-454 IN denotes to
T3346 455-460 NN denotes mouse
T3347 461-470 NN denotes sterility
T3348 470-472 , denotes ,
T3349 472-474 IN denotes so
T3351 475-479 IN denotes that
T3352 480-489 NNS denotes exchanges
T3353 490-493 MD denotes can
T3354 494-498 RB denotes only
T3355 499-501 VB denotes be
T3350 502-511 VBN denotes performed
T3356 512-514 IN denotes in
T3357 515-517 NN denotes ES
T3358 518-523 NNS denotes cells
T3359 524-525 -LRB- denotes (
T3360 525-527 CD denotes 16
T3361 527-528 -RRB- denotes )
T3362 528-529 . denotes .
R817 T3331 T3330 punct –,Thymidine
R818 T3332 T3328 compound Kinase,gene
R821 T3333 T3328 compound fusion,gene
R828 T3334 T3328 acl used,gene
R831 T3335 T3336 advmod most,frequently
R835 T3336 T3334 advmod frequently,used
R839 T3337 T3334 prep for,used
R844 T3338 T3339 amod positive,negative
R848 T3339 T3341 nmod negative,selection
R851 T3340 T3339 punct /,negative
R855 T3341 T3337 pobj selection,for
R859 T3342 T3341 prep in,selection
R862 T3343 T3342 pobj RMCE,in
R863 T3259 T3260 amod Most,experiments
R864 T3260 T3262 nsubjpass experiments,performed
R865 T3261 T3260 compound RMCE,experiments
R866 T3344 T3325 punct ", ",leads
R867 T3263 T3262 aux have,performed
R868 T3264 T3262 auxpass been,performed
R869 T3345 T3325 prep to,leads
R870 T3265 T3262 prep at,performed
R871 T3266 T3267 amod random,sites
R872 T3267 T3265 pobj sites,at
R873 T3346 T3347 compound mouse,sterility
R874 T3268 T3267 prep in,sites
R875 T3269 T3270 amod somatic,cell
R876 T3270 T3271 compound cell,lines
R877 T3271 T3268 pobj lines,in
R878 T3272 T3262 punct .,performed
R879 T3347 T3345 pobj sterility,to
R880 T3274 T3275 advmod Only,mice
R881 T3275 T3279 nsubjpass mice,reported
R882 T3276 T3275 det a,mice
R883 T3348 T3325 punct ", ",leads
R884 T3277 T3275 amod few,mice
R885 T3278 T3275 amod mutant,mice
R886 T3349 T3350 mark so,performed
R887 T3280 T3275 acl generated,mice
R888 T3281 T3280 agent by,generated
R889 T3282 T3281 pobj RMCE,by
R890 T3350 T3325 advcl performed,leads
R891 T3283 T3282 prep in,RMCE
R892 T3284 T3285 compound ES,cells
R893 T3351 T3350 mark that,performed
R894 T3285 T3283 pobj cells,in
R895 T3286 T3279 aux have,reported
R896 T3287 T3279 auxpass been,reported
R897 T3288 T3279 punct ", ",reported
R898 T3352 T3350 nsubjpass exchanges,performed
R899 T3289 T3279 cc but,reported
R900 T3290 T3291 det the,RMCE
R901 T3353 T3350 aux can,performed
R902 T3291 T3292 nsubj RMCE,introduced
R903 T3292 T3279 conj introduced,reported
R904 T3354 T3350 advmod only,performed
R905 T3293 T3292 advmod systematically,introduced
R906 T3294 T3295 det a,marker
R907 T3295 T3292 dobj marker,introduced
R908 T3296 T3295 amod selectable,marker
R909 T3355 T3350 auxpass be,performed
R910 T3297 T3298 punct (,15–17
R911 T3298 T3292 parataxis 15–17,introduced
R912 T3299 T3298 punct ),15–17
R913 T3356 T3350 prep in,performed
R914 T3300 T3292 punct ", ",introduced
R915 T3301 T3292 cc or,introduced
R916 T3357 T3358 compound ES,cells
R917 T3302 T3292 punct ", ",introduced
R918 T3303 T3304 advmod when,tested
R919 T3358 T3356 pobj cells,in
R920 T3304 T3305 advcl tested,proved
R921 T3359 T3360 punct (,16
R922 T3305 T3292 conj proved,introduced
R923 T3360 T3325 parataxis 16,leads
R924 T3306 T3304 prep without,tested
R925 T3307 T3308 det an,marker
R926 T3308 T3306 pobj marker,without
R927 T3309 T3308 amod incoming,marker
R928 T3310 T3305 punct ", ",proved
R929 T3311 T3305 oprd inefficient,proved
R930 T3312 T3313 punct (,12
R931 T3361 T3360 punct ),16
R932 T3313 T3305 parataxis 12,proved
R933 T3314 T3313 punct ),12
R934 T3315 T3292 punct .,introduced
R935 T3362 T3325 punct .,leads
R936 T3317 T3318 det A,report
R938 T3318 T3320 nsubj report,disclosed
R939 T3319 T3318 amod recent,report
R940 T3321 T3322 det an,problem
R942 T3322 T3320 dobj problem,disclosed
R943 T3323 T3322 amod additional,problem
R944 T3324 T3325 punct : ,leads
R946 T3327 T3328 det the,gene
R948 T3328 T3325 nsubj gene,leads
R949 T3329 T3330 compound Hygromycin,Thymidine
R950 T3330 T3332 compound Thymidine,Kinase