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PMC:1540739 / 15766-16526 JSONTXT 5 Projects

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Id Subject Object Predicate Lexical cue
T12028 0-3 CD denotes Six
T12030 4-15 JJ denotes independent
T12031 16-19 NN denotes p53
T12033 19-20 SYM denotes +
T12034 20-21 HYPH denotes /
T12032 21-24 NN denotes GFP
T12029 25-31 NNS denotes clones
T12036 32-36 VBD denotes were
T12035 37-45 VBN denotes injected
T12037 46-50 IN denotes into
T12038 51-62 NNS denotes blastocysts
T12039 63-66 CC denotes and
T12040 67-78 VBN denotes transferred
T12041 79-81 IN denotes to
T12042 82-88 JJ denotes pseudo
T12044 88-89 HYPH denotes -
T12043 89-97 JJ denotes pregnant
T12045 98-105 NNS denotes females
T12046 106-111 VBG denotes using
T12047 112-120 JJ denotes standard
T12048 121-131 NNS denotes procedures
T12049 131-132 . denotes .
T12050 132-174 sentence denotes Strikingly, no pregnancies were obtained.
T12051 133-143 RB denotes Strikingly
T12053 143-145 , denotes ,
T12054 145-147 DT denotes no
T12055 148-159 NNS denotes pregnancies
T12056 160-164 VBD denotes were
T12052 165-173 VBN denotes obtained
T12057 173-174 . denotes .
T12058 174-388 sentence denotes It has been shown that the p53 pathway is regulated very differently in ES and somatic cells: ES cells contain relatively high p53 levels and lack the p53-mediated DNA damage responses found in somatic cells (18).
T12059 175-177 PRP denotes It
T12061 178-181 VBZ denotes has
T12062 182-186 VBN denotes been
T12060 187-192 VBN denotes shown
T12064 193-197 IN denotes that
T12066 198-201 DT denotes the
T12068 202-205 NN denotes p53
T12067 206-213 NN denotes pathway
T12069 214-216 VBZ denotes is
T12065 217-226 VBN denotes regulated
T12070 227-231 RB denotes very
T12071 232-243 RB denotes differently
T12072 244-246 IN denotes in
T12073 247-249 NN denotes ES
T12075 250-253 CC denotes and
T12076 254-261 JJ denotes somatic
T12074 262-267 NNS denotes cells
T12077 267-269 : denotes :
T12078 269-271 NN denotes ES
T12079 272-277 NNS denotes cells
T12063 278-285 VBP denotes contain
T12080 286-296 RB denotes relatively
T12081 297-301 JJ denotes high
T12083 302-305 NN denotes p53
T12082 306-312 NNS denotes levels
T12084 313-316 CC denotes and
T12085 317-321 VBP denotes lack
T12086 322-325 DT denotes the
T12088 326-329 NN denotes p53
T12089 329-330 HYPH denotes -
T12090 330-338 JJ denotes mediated
T12091 339-342 NN denotes DNA
T12092 343-349 NN denotes damage
T12087 350-359 NNS denotes responses
T12093 360-365 VBN denotes found
T12094 366-368 IN denotes in
T12095 369-376 JJ denotes somatic
T12096 377-382 NNS denotes cells
T12097 383-384 -LRB- denotes (
T12098 384-386 CD denotes 18
T12099 386-387 -RRB- denotes )
T12100 387-388 . denotes .
T12101 388-760 sentence denotes This, together with the observation that p53 levels decrease during mouse embryogenesis (19), suggested an explanation for the observed lack of pregnancies: we speculate that the high levels of p53GFP in the ES cells injected into blastocysts might have prevented normal embryonic development once these cells began to differentiate and the p53 pathway became functional.
T12102 389-393 DT denotes This
T12104 393-395 , denotes ,
T12105 395-403 RB denotes together
T12106 404-408 IN denotes with
T12107 409-412 DT denotes the
T12108 413-424 NN denotes observation
T12109 425-429 IN denotes that
T12111 430-433 NN denotes p53
T12112 434-440 NNS denotes levels
T12110 441-449 VBP denotes decrease
T12113 450-456 IN denotes during
T12114 457-462 NN denotes mouse
T12115 463-476 NN denotes embryogenesis
T12116 477-478 -LRB- denotes (
T12117 478-480 CD denotes 19
T12118 480-481 -RRB- denotes )
T12119 481-483 , denotes ,
T12103 483-492 VBD denotes suggested
T12121 493-495 DT denotes an
T12122 496-507 NN denotes explanation
T12123 508-511 IN denotes for
T12124 512-515 DT denotes the
T12126 516-524 VBN denotes observed
T12125 525-529 NN denotes lack
T12127 530-532 IN denotes of
T12128 533-544 NNS denotes pregnancies
T12129 544-546 : denotes :
T12130 546-548 PRP denotes we
T12120 549-558 VBP denotes speculate
T12131 559-563 IN denotes that
T12133 564-567 DT denotes the
T12135 568-572 JJ denotes high
T12134 573-579 NNS denotes levels
T12136 580-582 IN denotes of
T12137 583-589 NN denotes p53GFP
T12138 590-592 IN denotes in
T12139 593-596 DT denotes the
T12141 597-599 NN denotes ES
T12140 600-605 NNS denotes cells
T12142 606-614 VBN denotes injected
T12143 615-619 IN denotes into
T12144 620-631 NNS denotes blastocysts
T12145 632-637 MD denotes might
T12146 638-642 VB denotes have
T12132 643-652 VBN denotes prevented
T12147 653-659 JJ denotes normal
T12149 660-669 JJ denotes embryonic
T12148 670-681 NN denotes development
T12150 682-686 IN denotes once
T12152 687-692 DT denotes these
T12153 693-698 NNS denotes cells
T12151 699-704 VBD denotes began
T12154 705-707 TO denotes to
T12155 708-721 VB denotes differentiate
T12156 722-725 CC denotes and
T12157 726-729 DT denotes the
T12159 730-733 NN denotes p53
T12158 734-741 NN denotes pathway
T12160 742-748 VBD denotes became
T12161 749-759 JJ denotes functional
T12162 759-760 . denotes .
R2984 T12028 T12029 nummod Six,clones
R2986 T12029 T12035 nsubjpass clones,injected
R2987 T12030 T12029 amod independent,clones
R2989 T12031 T12032 nmod p53,GFP
R2990 T12032 T12029 compound GFP,clones
R2991 T12033 T12032 punct +,GFP
R2993 T12034 T12032 punct /,GFP
R2994 T12036 T12035 auxpass were,injected
R2996 T12037 T12035 prep into,injected
R2997 T12038 T12037 pobj blastocysts,into
R2998 T12039 T12035 cc and,injected
R3000 T12040 T12035 conj transferred,injected
R3001 T12041 T12040 prep to,transferred
R3002 T12042 T12043 amod pseudo,pregnant
R3004 T12043 T12045 amod pregnant,females
R3005 T12044 T12043 punct -,pregnant
R3007 T12045 T12041 pobj females,to
R3008 T12046 T12040 advcl using,transferred
R3009 T12047 T12048 amod standard,procedures
R3011 T12048 T12046 dobj procedures,using
R3012 T12049 T12035 punct .,injected
R3014 T12051 T12052 advmod Strikingly,obtained
R3015 T12053 T12052 punct ", ",obtained
R3017 T12054 T12055 det no,pregnancies
R3018 T12055 T12052 nsubjpass pregnancies,obtained
R3019 T12056 T12052 auxpass were,obtained
R3021 T12057 T12052 punct .,obtained
R3022 T12059 T12060 nsubjpass It,shown
R3024 T12060 T12063 ccomp shown,contain
R3027 T12061 T12060 aux has,shown
R3029 T12062 T12060 auxpass been,shown
R3030 T12064 T12065 mark that,regulated
R3031 T12065 T12060 ccomp regulated,shown
R3032 T12066 T12067 det the,pathway
R3033 T12067 T12065 nsubjpass pathway,regulated
R3035 T12068 T12067 compound p53,pathway
R3036 T12069 T12065 auxpass is,regulated
R3037 T12070 T12071 advmod very,differently
R3038 T12071 T12065 advmod differently,regulated
R3040 T12072 T12065 prep in,regulated
R3041 T12073 T12074 nmod ES,cells
R3042 T12074 T12072 pobj cells,in
R3044 T12075 T12073 cc and,ES
R3045 T12076 T12073 conj somatic,ES
R3047 T12077 T12063 punct : ,contain
R3048 T12078 T12079 compound ES,cells
R3049 T12079 T12063 nsubj cells,contain
R3051 T12080 T12081 advmod relatively,high
R3052 T12081 T12082 amod high,levels
R3053 T12082 T12063 dobj levels,contain
R3054 T12083 T12082 compound p53,levels
R3055 T12084 T12063 cc and,contain
R3057 T12085 T12063 conj lack,contain
R3058 T12086 T12087 det the,responses
R3059 T12087 T12085 dobj responses,lack
R3061 T12088 T12087 nmod p53,responses
R3062 T12089 T12088 punct -,p53
R3063 T12090 T12088 amod mediated,p53
R3065 T12091 T12092 compound DNA,damage
R3066 T12092 T12087 compound damage,responses
R3068 T12093 T12087 acl found,responses
R3069 T12094 T12093 prep in,found
R3070 T12095 T12096 amod somatic,cells
R3072 T12096 T12094 pobj cells,in
R3073 T12097 T12098 punct (,18
R3074 T12098 T12085 parataxis 18,lack
R3075 T12099 T12098 punct ),18
R3077 T12100 T12063 punct .,contain
R3079 T12102 T12103 nsubj This,suggested
R3081 T12103 T12120 ccomp suggested,speculate
R3082 T12104 T12103 punct ", ",suggested
R3083 T12105 T12103 advmod together,suggested
R3084 T12106 T12105 prep with,together
R3085 T12107 T12108 det the,observation
R3086 T12108 T12106 pobj observation,with
R3088 T12109 T12110 mark that,decrease
R3089 T12110 T12108 acl decrease,observation
R3090 T12111 T12112 compound p53,levels
R3092 T12112 T12110 nsubj levels,decrease
R3093 T12113 T12110 prep during,decrease
R3094 T12114 T12115 compound mouse,embryogenesis
R3096 T12115 T12113 pobj embryogenesis,during
R3097 T12116 T12117 punct (,19
R3099 T12117 T12110 parataxis 19,decrease
R3100 T12118 T12117 punct ),19
R3101 T12119 T12103 punct ", ",suggested
R3103 T12121 T12122 det an,explanation
R3105 T12122 T12103 dobj explanation,suggested
R3106 T12123 T12122 prep for,explanation
R3107 T12124 T12125 det the,lack
R3109 T12125 T12123 pobj lack,for
R3110 T12126 T12125 amod observed,lack
R3111 T12127 T12125 prep of,lack
R3113 T12128 T12127 pobj pregnancies,of
R3114 T12129 T12120 punct : ,speculate
R3115 T12130 T12120 nsubj we,speculate
R3117 T12131 T12132 mark that,prevented
R3118 T12132 T12120 ccomp prevented,speculate
R3120 T12133 T12134 det the,levels
R3121 T12134 T12132 nsubj levels,prevented
R3122 T12135 T12134 amod high,levels
R3124 T12136 T12134 prep of,levels
R3125 T12137 T12136 pobj p53GFP,of
R3127 T12138 T12134 prep in,levels
R3128 T12139 T12140 det the,cells
R3129 T12140 T12138 pobj cells,in
R3130 T12141 T12140 compound ES,cells
R3132 T12142 T12140 acl injected,cells
R3133 T12143 T12142 prep into,injected
R3134 T12144 T12143 pobj blastocysts,into
R3135 T12145 T12132 aux might,prevented
R3136 T12146 T12132 aux have,prevented
R3138 T12147 T12148 amod normal,development
R3139 T12148 T12132 dobj development,prevented
R3140 T12149 T12148 amod embryonic,development
R3142 T12150 T12151 prep once,began
R3143 T12151 T12132 advcl began,prevented
R3144 T12152 T12153 det these,cells
R3146 T12153 T12151 nsubj cells,began
R3147 T12154 T12155 aux to,differentiate
R3148 T12155 T12151 xcomp differentiate,began
R3150 T12156 T12151 cc and,began
R3151 T12157 T12158 det the,pathway
R3153 T12158 T12160 nsubj pathway,became
R3154 T12159 T12158 compound p53,pathway
R3155 T12160 T12151 conj became,began
R3157 T12161 T12160 acomp functional,became
R3158 T12162 T12120 punct .,speculate