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PMC:1482699 / 20919-22778 JSONTXT 4 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T13285 0-3 DT denotes The
T13287 4-6 NN denotes HG
T13286 7-16 NN denotes phenotype
T13288 17-19 VBZ denotes is
T13290 20-23 IN denotes due
T13291 24-26 IN denotes to
T13292 27-30 DT denotes the
T13293 31-39 NN denotes deletion
T13294 40-42 IN denotes of
T13295 43-48 NN denotes Socs2
T13296 48-50 , denotes ,
T13297 50-59 RB denotes therefore
T13298 60-62 PRP denotes we
T13289 63-71 VBD denotes reasoned
T13299 72-76 IN denotes that
T13301 77-80 NN denotes QTL
T13302 81-83 IN denotes on
T13303 84-87 NN denotes MMU
T13304 87-88 CD denotes 2
T13305 88-90 , denotes ,
T13306 90-91 CD denotes 9
T13307 91-93 , denotes ,
T13308 93-95 CD denotes 11
T13309 96-99 CC denotes and
T13310 100-102 CD denotes 17
T13311 103-114 VBG denotes interacting
T13312 115-119 IN denotes with
T13313 120-122 NN denotes hg
T13314 123-131 RB denotes possibly
T13300 132-141 VBP denotes represent
T13315 142-151 NN denotes variation
T13316 152-158 IN denotes within
T13317 159-164 NNS denotes genes
T13318 165-178 VBG denotes participating
T13319 179-181 IN denotes in
T13320 182-189 JJ denotes various
T13321 190-197 NNS denotes aspects
T13322 198-200 IN denotes of
T13323 201-203 NN denotes Gh
T13324 204-212 NN denotes function
T13325 212-213 . denotes .
T13326 213-391 sentence denotes To select candidate genes for sequencing we identified genes known to be or potentially involved in Gh signaling, are responsive to Gh or that propagate downstream Gh functions.
T13327 214-216 TO denotes To
T13328 217-223 VB denotes select
T13330 224-233 NN denotes candidate
T13331 234-239 NNS denotes genes
T13332 240-243 IN denotes for
T13333 244-254 NN denotes sequencing
T13334 255-257 PRP denotes we
T13329 258-268 VBD denotes identified
T13335 269-274 NNS denotes genes
T13336 275-280 VBN denotes known
T13337 281-283 TO denotes to
T13338 284-286 VB denotes be
T13339 287-289 CC denotes or
T13340 290-301 RB denotes potentially
T13341 302-310 VBN denotes involved
T13342 311-313 IN denotes in
T13343 314-316 NN denotes Gh
T13344 317-326 NN denotes signaling
T13345 326-328 , denotes ,
T13346 328-331 VBP denotes are
T13347 332-342 JJ denotes responsive
T13348 343-345 IN denotes to
T13349 346-348 NN denotes Gh
T13350 349-351 CC denotes or
T13351 352-356 WDT denotes that
T13352 357-366 VBP denotes propagate
T13353 367-377 JJ denotes downstream
T13355 378-380 NN denotes Gh
T13354 381-390 NNS denotes functions
T13356 390-391 . denotes .
T13357 391-604 sentence denotes Forty-four hg modifier candidate genes were identified from primary literature, reviews and book chapters and coordinated using the GenMAPP (Gene MicroArray Pathway Profiler) pathway building software (Figure 5).
T13358 392-397 CD denotes Forty
T13360 397-398 HYPH denotes -
T13359 398-402 CD denotes four
T13362 403-405 NN denotes hg
T13363 406-414 NN denotes modifier
T13364 415-424 NN denotes candidate
T13361 425-430 NNS denotes genes
T13366 431-435 VBD denotes were
T13365 436-446 VBN denotes identified
T13367 447-451 IN denotes from
T13368 452-459 JJ denotes primary
T13369 460-470 NN denotes literature
T13370 470-472 , denotes ,
T13371 472-479 NNS denotes reviews
T13372 480-483 CC denotes and
T13373 484-488 NN denotes book
T13374 489-497 NNS denotes chapters
T13375 498-501 CC denotes and
T13376 502-513 VBN denotes coordinated
T13377 514-519 VBG denotes using
T13378 520-523 DT denotes the
T13380 524-531 NNP denotes GenMAPP
T13381 532-533 -LRB- denotes (
T13382 533-537 NNP denotes Gene
T13383 538-548 NNP denotes MicroArray
T13385 549-556 NNP denotes Pathway
T13384 557-565 NNP denotes Profiler
T13386 565-566 -RRB- denotes )
T13387 567-574 NN denotes pathway
T13388 575-583 NN denotes building
T13379 584-592 NN denotes software
T13389 593-594 -LRB- denotes (
T13390 594-600 NN denotes Figure
T13391 601-602 CD denotes 5
T13392 602-603 -RRB- denotes )
T13393 603-604 . denotes .
T13394 604-768 sentence denotes The coding region of each gene was sequenced from the CAST strain and compared to the publicly available B6 sequence to identify polymorphisms (Additional File 4).
T13395 605-608 DT denotes The
T13397 609-615 NN denotes coding
T13396 616-622 NN denotes region
T13399 623-625 IN denotes of
T13400 626-630 DT denotes each
T13401 631-635 NN denotes gene
T13402 636-639 VBD denotes was
T13398 640-649 VBN denotes sequenced
T13403 650-654 IN denotes from
T13404 655-658 DT denotes the
T13406 659-663 NN denotes CAST
T13405 664-670 NN denotes strain
T13407 671-674 CC denotes and
T13408 675-683 VBN denotes compared
T13409 684-686 IN denotes to
T13410 687-690 DT denotes the
T13412 691-699 RB denotes publicly
T13413 700-709 JJ denotes available
T13414 710-712 NN denotes B6
T13411 713-721 NN denotes sequence
T13415 722-724 TO denotes to
T13416 725-733 VB denotes identify
T13417 734-747 NNS denotes polymorphisms
T13418 748-749 -LRB- denotes (
T13420 749-759 JJ denotes Additional
T13419 760-764 NN denotes File
T13421 765-766 CD denotes 4
T13422 766-767 -RRB- denotes )
T13423 767-768 . denotes .
T13424 768-906 sentence denotes A total of 94.492 kbp was sequenced (75.378 kbp CDS and 19.114 Kbp 5' and 3' untranslated region (UTR)), representing 25,083 amino acids.
T13425 769-770 DT denotes A
T13426 771-776 NN denotes total
T13428 777-779 IN denotes of
T13429 780-786 CD denotes 94.492
T13430 787-790 NN denotes kbp
T13431 791-794 VBD denotes was
T13427 795-804 VBN denotes sequenced
T13432 805-806 -LRB- denotes (
T13434 806-812 CD denotes 75.378
T13435 813-816 NN denotes kbp
T13433 817-820 NN denotes CDS
T13436 821-824 CC denotes and
T13437 825-831 CD denotes 19.114
T13438 832-835 NN denotes Kbp
T13440 836-837 CD denotes 5
T13441 837-838 SYM denotes '
T13442 839-842 CC denotes and
T13443 843-844 CD denotes 3
T13444 844-845 SYM denotes '
T13445 846-858 JJ denotes untranslated
T13439 859-865 NN denotes region
T13446 866-867 -LRB- denotes (
T13447 867-870 NN denotes UTR
T13448 870-871 -RRB- denotes )
T13449 871-872 -RRB- denotes )
T13450 872-874 , denotes ,
T13451 874-886 VBG denotes representing
T13452 887-893 CD denotes 25,083
T13454 894-899 NN denotes amino
T13453 900-905 NNS denotes acids
T13455 905-906 . denotes .
T13456 906-1138 sentence denotes Comparison with the public B6 assembly (May 2004 University of California, Santa Cruz (UCSC [28]) mm5 genome assembly, National Center for Biotechnology Information (NCBI) Build 33) identified 307 polymorphisms between CAST and B6.
T13457 907-917 NN denotes Comparison
T13459 918-922 IN denotes with
T13460 923-926 DT denotes the
T13462 927-933 JJ denotes public
T13463 934-936 NN denotes B6
T13461 937-945 NN denotes assembly
T13464 946-947 -LRB- denotes (
T13466 947-950 NNP denotes May
T13468 951-955 CD denotes 2004
T13467 956-966 NNP denotes University
T13469 967-969 IN denotes of
T13470 970-980 NNP denotes California
T13471 980-982 , denotes ,
T13472 982-987 NNP denotes Santa
T13473 988-992 NNP denotes Cruz
T13474 993-994 -LRB- denotes (
T13476 994-998 NNP denotes UCSC
T13477 999-1000 -LRB- denotes [
T13475 1000-1002 CD denotes 28
T13478 1002-1003 -RRB- denotes ]
T13479 1003-1004 -RRB- denotes )
T13480 1005-1008 NN denotes mm5
T13482 1009-1015 NN denotes genome
T13481 1016-1024 NN denotes assembly
T13483 1024-1026 , denotes ,
T13484 1026-1034 NNP denotes National
T13485 1035-1041 NNP denotes Center
T13486 1042-1045 IN denotes for
T13487 1046-1059 NNP denotes Biotechnology
T13488 1060-1071 NNP denotes Information
T13489 1072-1073 -LRB- denotes (
T13490 1073-1077 NNP denotes NCBI
T13491 1077-1078 -RRB- denotes )
T13465 1079-1084 NN denotes Build
T13492 1085-1087 CD denotes 33
T13493 1087-1088 -RRB- denotes )
T13458 1089-1099 VBN denotes identified
T13494 1100-1103 CD denotes 307
T13495 1104-1117 NNS denotes polymorphisms
T13496 1118-1125 IN denotes between
T13497 1126-1130 NN denotes CAST
T13498 1131-1134 CC denotes and
T13499 1135-1137 NN denotes B6
T13500 1137-1138 . denotes .
T13501 1138-1260 sentence denotes Of these, 295 were single nucleotide polymorphisms (SNP) and 12 were insertions or deletions in CAST (Additional File 4).
T13502 1139-1141 IN denotes Of
T13504 1142-1147 DT denotes these
T13505 1147-1149 , denotes ,
T13506 1149-1152 CD denotes 295
T13503 1153-1157 VBD denotes were
T13507 1158-1164 JJ denotes single
T13509 1165-1175 NN denotes nucleotide
T13508 1176-1189 NNS denotes polymorphisms
T13510 1190-1191 -LRB- denotes (
T13511 1191-1194 NN denotes SNP
T13512 1194-1195 -RRB- denotes )
T13513 1196-1199 CC denotes and
T13514 1200-1202 CD denotes 12
T13515 1203-1207 VBD denotes were
T13516 1208-1218 NNS denotes insertions
T13517 1219-1221 CC denotes or
T13518 1222-1231 NNS denotes deletions
T13519 1232-1234 IN denotes in
T13520 1235-1239 NN denotes CAST
T13521 1240-1241 -LRB- denotes (
T13523 1241-1251 JJ denotes Additional
T13522 1252-1256 NN denotes File
T13524 1257-1258 CD denotes 4
T13525 1258-1259 -RRB- denotes )
T13526 1259-1260 . denotes .
T13527 1260-1327 sentence denotes All 12 insertions or deletions were located within 5' and 3' UTRs.
T13528 1261-1264 PDT denotes All
T13530 1265-1267 CD denotes 12
T13529 1268-1278 NNS denotes insertions
T13532 1279-1281 CC denotes or
T13533 1282-1291 NNS denotes deletions
T13534 1292-1296 VBD denotes were
T13531 1297-1304 VBN denotes located
T13535 1305-1311 IN denotes within
T13536 1312-1313 CD denotes 5
T13538 1313-1314 SYM denotes '
T13539 1315-1318 CC denotes and
T13540 1319-1320 CD denotes 3
T13541 1320-1321 SYM denotes '
T13537 1322-1326 NNS denotes UTRs
T13542 1326-1327 . denotes .
T13543 1327-1422 sentence denotes Fifty-six nonsynonomous SNP (nsSNP) were identified in 14 different genes (Additional File 4).
T13544 1328-1333 CD denotes Fifty
T13546 1333-1334 HYPH denotes -
T13545 1334-1337 CD denotes six
T13548 1338-1351 JJ denotes nonsynonomous
T13547 1352-1355 NN denotes SNP
T13550 1356-1357 -LRB- denotes (
T13551 1357-1362 NN denotes nsSNP
T13552 1362-1363 -RRB- denotes )
T13553 1364-1368 VBD denotes were
T13549 1369-1379 VBN denotes identified
T13554 1380-1382 IN denotes in
T13555 1383-1385 CD denotes 14
T13557 1386-1395 JJ denotes different
T13556 1396-1401 NNS denotes genes
T13558 1402-1403 -LRB- denotes (
T13560 1403-1413 JJ denotes Additional
T13559 1414-1418 NN denotes File
T13561 1419-1420 CD denotes 4
T13562 1420-1421 -RRB- denotes )
T13563 1421-1422 . denotes .
T13564 1422-1694 sentence denotes PolyPhen [29] and SIFT [30] are software programs designed to identify nsSNP which potentially alter protein function by evaluating evolutionary conservation at specific amino acid residues using a multiple sequence alignment of protein sequences homologous to the query.
T13565 1423-1431 NNP denotes PolyPhen
T13567 1432-1433 -LRB- denotes [
T13568 1433-1435 CD denotes 29
T13569 1435-1436 -RRB- denotes ]
T13570 1437-1440 CC denotes and
T13571 1441-1445 NN denotes SIFT
T13572 1446-1447 -LRB- denotes [
T13573 1447-1449 CD denotes 30
T13574 1449-1450 -RRB- denotes ]
T13566 1451-1454 VBP denotes are
T13575 1455-1463 NN denotes software
T13576 1464-1472 NNS denotes programs
T13577 1473-1481 VBN denotes designed
T13578 1482-1484 TO denotes to
T13579 1485-1493 VB denotes identify
T13580 1494-1499 NN denotes nsSNP
T13581 1500-1505 WDT denotes which
T13583 1506-1517 RB denotes potentially
T13582 1518-1523 VBP denotes alter
T13584 1524-1531 NN denotes protein
T13585 1532-1540 NN denotes function
T13586 1541-1543 IN denotes by
T13587 1544-1554 VBG denotes evaluating
T13588 1555-1567 JJ denotes evolutionary
T13589 1568-1580 NN denotes conservation
T13590 1581-1583 IN denotes at
T13591 1584-1592 JJ denotes specific
T13593 1593-1598 NN denotes amino
T13594 1599-1603 NN denotes acid
T13592 1604-1612 NNS denotes residues
T13595 1613-1618 VBG denotes using
T13596 1619-1620 DT denotes a
T13598 1621-1629 JJ denotes multiple
T13599 1630-1638 NN denotes sequence
T13597 1639-1648 NN denotes alignment
T13600 1649-1651 IN denotes of
T13601 1652-1659 NN denotes protein
T13602 1660-1669 NNS denotes sequences
T13603 1670-1680 JJ denotes homologous
T13604 1681-1683 IN denotes to
T13605 1684-1687 DT denotes the
T13606 1688-1693 NN denotes query
T13607 1693-1694 . denotes .
T13608 1694-1859 sentence denotes When applied to our data set PolyPhen, SIFT or both programs predicted that 15 of the 56 nsSNP in 9 different genes would possibly alter protein function (Table 7).
T13609 1695-1699 WRB denotes When
T13610 1700-1707 VBN denotes applied
T13612 1708-1710 IN denotes to
T13613 1711-1714 PRP$ denotes our
T13615 1715-1719 NNS denotes data
T13614 1720-1723 NN denotes set
T13616 1724-1732 NNP denotes PolyPhen
T13617 1732-1734 , denotes ,
T13618 1734-1738 NNP denotes SIFT
T13619 1739-1741 CC denotes or
T13620 1742-1746 DT denotes both
T13621 1747-1755 NNS denotes programs
T13611 1756-1765 VBD denotes predicted
T13622 1766-1770 IN denotes that
T13624 1771-1773 CD denotes 15
T13626 1774-1776 IN denotes of
T13627 1777-1780 DT denotes the
T13625 1781-1783 CD denotes 56
T13628 1784-1789 NN denotes nsSNP
T13629 1790-1792 IN denotes in
T13630 1793-1794 CD denotes 9
T13632 1795-1804 JJ denotes different
T13631 1805-1810 NNS denotes genes
T13633 1811-1816 MD denotes would
T13634 1817-1825 RB denotes possibly
T13623 1826-1831 VB denotes alter
T13635 1832-1839 NN denotes protein
T13636 1840-1848 NN denotes function
T13637 1849-1850 -LRB- denotes (
T13638 1850-1855 NN denotes Table
T13639 1856-1857 CD denotes 7
T13640 1857-1858 -RRB- denotes )
T13641 1858-1859 . denotes .
R3999 T13285 T13286 det The,phenotype
R4000 T13286 T13288 nsubj phenotype,is
R4001 T13287 T13286 compound HG,phenotype
R4002 T13288 T13289 ccomp is,reasoned
R4003 T13290 T13288 prep due,is
R4004 T13291 T13290 pcomp to,due
R4005 T13292 T13293 det the,deletion
R4006 T13293 T13290 pobj deletion,due
R4007 T13294 T13293 prep of,deletion
R4008 T13295 T13294 pobj Socs2,of
R4009 T13296 T13289 punct ", ",reasoned
R4010 T13297 T13289 advmod therefore,reasoned
R4011 T13298 T13289 nsubj we,reasoned
R4012 T13299 T13300 mark that,represent
R4013 T13300 T13289 ccomp represent,reasoned
R4014 T13301 T13300 nsubj QTL,represent
R4015 T13302 T13301 prep on,QTL
R4016 T13303 T13304 nmod MMU,2
R4017 T13304 T13302 pobj 2,on
R4018 T13305 T13304 punct ", ",2
R4019 T13306 T13304 conj 9,2
R4020 T13307 T13306 punct ", ",9
R4021 T13308 T13306 conj 11,9
R4022 T13309 T13308 cc and,11
R4023 T13310 T13308 conj 17,11
R4024 T13311 T13301 acl interacting,QTL
R4025 T13312 T13311 prep with,interacting
R4026 T13313 T13312 pobj hg,with
R4027 T13314 T13300 advmod possibly,represent
R4028 T13315 T13300 dobj variation,represent
R4029 T13316 T13315 prep within,variation
R4030 T13317 T13316 pobj genes,within
R4031 T13318 T13317 acl participating,genes
R4032 T13319 T13318 prep in,participating
R4033 T13320 T13321 amod various,aspects
R4034 T13321 T13319 pobj aspects,in
R4035 T13322 T13321 prep of,aspects
R4036 T13323 T13324 compound Gh,function
R4037 T13324 T13322 pobj function,of
R4038 T13325 T13289 punct .,reasoned
R4039 T13327 T13328 aux To,select
R4040 T13328 T13329 advcl select,identified
R4041 T13330 T13331 compound candidate,genes
R4042 T13331 T13328 dobj genes,select
R4043 T13332 T13331 prep for,genes
R4044 T13333 T13332 pobj sequencing,for
R4045 T13334 T13329 nsubj we,identified
R4046 T13335 T13329 dobj genes,identified
R4047 T13336 T13335 acl known,genes
R4048 T13337 T13338 aux to,be
R4049 T13338 T13336 xcomp be,known
R4050 T13339 T13336 cc or,known
R4051 T13340 T13336 conj potentially,known
R4052 T13341 T13340 dep involved,potentially
R4053 T13342 T13341 prep in,involved
R4054 T13343 T13344 compound Gh,signaling
R4055 T13344 T13342 pobj signaling,in
R4056 T13345 T13336 punct ", ",known
R4057 T13346 T13336 conj are,known
R4058 T13347 T13346 acomp responsive,are
R4059 T13348 T13347 prep to,responsive
R4060 T13349 T13348 pobj Gh,to
R4061 T13350 T13346 cc or,are
R4062 T13351 T13352 dep that,propagate
R4063 T13352 T13346 conj propagate,are
R4064 T13353 T13354 amod downstream,functions
R4065 T13354 T13352 dobj functions,propagate
R4066 T13355 T13354 compound Gh,functions
R4067 T13356 T13329 punct .,identified
R4068 T13358 T13359 compound Forty,four
R4069 T13359 T13361 nummod four,genes
R4070 T13360 T13359 punct -,four
R4071 T13361 T13365 nsubjpass genes,identified
R4072 T13362 T13363 compound hg,modifier
R4073 T13363 T13361 compound modifier,genes
R4074 T13364 T13361 compound candidate,genes
R4075 T13366 T13365 auxpass were,identified
R4076 T13367 T13365 prep from,identified
R4077 T13368 T13369 amod primary,literature
R4078 T13369 T13367 pobj literature,from
R4079 T13370 T13369 punct ", ",literature
R4080 T13371 T13369 conj reviews,literature
R4081 T13372 T13371 cc and,reviews
R4082 T13373 T13374 compound book,chapters
R4083 T13374 T13371 conj chapters,reviews
R4084 T13375 T13365 cc and,identified
R4085 T13376 T13365 conj coordinated,identified
R4086 T13377 T13376 advcl using,coordinated
R4087 T13378 T13379 det the,software
R4088 T13379 T13377 dobj software,using
R4089 T13380 T13379 nmod GenMAPP,software
R4090 T13381 T13380 punct (,GenMAPP
R4091 T13382 T13383 compound Gene,MicroArray
R4092 T13383 T13384 compound MicroArray,Profiler
R4093 T13384 T13380 appos Profiler,GenMAPP
R4094 T13385 T13384 compound Pathway,Profiler
R4095 T13386 T13379 punct ),software
R4096 T13387 T13388 compound pathway,building
R4097 T13388 T13379 compound building,software
R4098 T13389 T13390 punct (,Figure
R4099 T13390 T13376 parataxis Figure,coordinated
R4100 T13391 T13390 nummod 5,Figure
R4101 T13392 T13390 punct ),Figure
R4102 T13393 T13365 punct .,identified
R4103 T13395 T13396 det The,region
R4104 T13396 T13398 nsubjpass region,sequenced
R4105 T13397 T13396 compound coding,region
R4106 T13399 T13396 prep of,region
R4107 T13400 T13401 det each,gene
R4108 T13401 T13399 pobj gene,of
R4109 T13402 T13398 auxpass was,sequenced
R4110 T13403 T13398 prep from,sequenced
R4111 T13404 T13405 det the,strain
R4112 T13405 T13403 pobj strain,from
R4113 T13406 T13405 compound CAST,strain
R4114 T13407 T13398 cc and,sequenced
R4115 T13408 T13398 conj compared,sequenced
R4116 T13409 T13408 prep to,compared
R4117 T13410 T13411 det the,sequence
R4118 T13411 T13409 pobj sequence,to
R4119 T13412 T13413 advmod publicly,available
R4120 T13413 T13411 amod available,sequence
R4121 T13414 T13411 compound B6,sequence
R4122 T13415 T13416 aux to,identify
R4123 T13416 T13408 advcl identify,compared
R4124 T13417 T13416 dobj polymorphisms,identify
R4125 T13418 T13419 punct (,File
R4126 T13419 T13408 parataxis File,compared
R4127 T13420 T13419 amod Additional,File
R4128 T13421 T13419 nummod 4,File
R4129 T13422 T13419 punct ),File
R4130 T13423 T13398 punct .,sequenced
R4131 T13425 T13426 det A,total
R4132 T13426 T13427 nsubjpass total,sequenced
R4133 T13428 T13426 prep of,total
R4134 T13429 T13430 nummod 94.492,kbp
R4135 T13430 T13428 pobj kbp,of
R4136 T13431 T13427 auxpass was,sequenced
R4137 T13432 T13433 punct (,CDS
R4138 T13433 T13427 parataxis CDS,sequenced
R4139 T13434 T13435 nummod 75.378,kbp
R4140 T13435 T13433 compound kbp,CDS
R4141 T13436 T13433 cc and,CDS
R4142 T13437 T13438 nummod 19.114,Kbp
R4143 T13438 T13439 nmod Kbp,region
R4144 T13439 T13433 conj region,CDS
R4145 T13440 T13438 nummod 5,Kbp
R4146 T13441 T13440 punct ',5
R4147 T13442 T13438 cc and,Kbp
R4148 T13443 T13438 conj 3,Kbp
R4149 T13444 T13443 punct ',3
R4150 T13445 T13439 amod untranslated,region
R4151 T13446 T13439 punct (,region
R4152 T13447 T13439 appos UTR,region
R4153 T13448 T13439 punct ),region
R4154 T13449 T13433 punct ),CDS
R4155 T13450 T13427 punct ", ",sequenced
R4156 T13451 T13427 advcl representing,sequenced
R4157 T13452 T13453 nummod "25,083",acids
R4158 T13453 T13451 dobj acids,representing
R4159 T13454 T13453 compound amino,acids
R4160 T13455 T13427 punct .,sequenced
R4161 T13457 T13458 nsubj Comparison,identified
R4162 T13459 T13457 prep with,Comparison
R4163 T13460 T13461 det the,assembly
R4164 T13461 T13459 pobj assembly,with
R4165 T13462 T13461 amod public,assembly
R4166 T13463 T13461 compound B6,assembly
R4167 T13464 T13465 punct (,Build
R4168 T13465 T13457 parataxis Build,Comparison
R4169 T13466 T13467 npadvmod May,University
R4170 T13467 T13465 dep University,Build
R4171 T13468 T13466 npadvmod 2004,May
R4172 T13469 T13467 prep of,University
R4173 T13470 T13469 pobj California,of
R4174 T13471 T13467 punct ", ",University
R4175 T13472 T13473 compound Santa,Cruz
R4176 T13473 T13467 npadvmod Cruz,University
R4177 T13474 T13475 punct (,28
R4178 T13475 T13467 parataxis 28,University
R4179 T13476 T13475 dep UCSC,28
R4180 T13477 T13475 punct [,28
R4181 T13478 T13475 punct ],28
R4182 T13479 T13475 punct ),28
R4183 T13480 T13481 compound mm5,assembly
R4184 T13481 T13465 dep assembly,Build
R4185 T13482 T13481 compound genome,assembly
R4186 T13483 T13465 punct ", ",Build
R4187 T13484 T13485 compound National,Center
R4188 T13485 T13465 dep Center,Build
R4189 T13486 T13485 prep for,Center
R4190 T13487 T13488 compound Biotechnology,Information
R4191 T13488 T13486 pobj Information,for
R4192 T13489 T13485 punct (,Center
R4193 T13490 T13485 appos NCBI,Center
R4194 T13491 T13485 punct ),Center
R4195 T13492 T13465 nummod 33,Build
R4196 T13493 T13465 punct ),Build
R4197 T13494 T13495 nummod 307,polymorphisms
R4198 T13495 T13458 dobj polymorphisms,identified
R4199 T13496 T13495 prep between,polymorphisms
R4200 T13497 T13496 pobj CAST,between
R4201 T13498 T13497 cc and,CAST
R4202 T13499 T13497 conj B6,CAST
R4203 T13500 T13458 punct .,identified
R4204 T13502 T13503 prep Of,were
R4205 T13504 T13502 pobj these,Of
R4206 T13505 T13503 punct ", ",were
R4207 T13506 T13503 nsubj 295,were
R4208 T13507 T13508 amod single,polymorphisms
R4209 T13508 T13503 attr polymorphisms,were
R4210 T13509 T13508 compound nucleotide,polymorphisms
R4211 T13510 T13508 punct (,polymorphisms
R4212 T13511 T13508 appos SNP,polymorphisms
R4213 T13512 T13503 punct ),were
R4214 T13513 T13503 cc and,were
R4215 T13514 T13515 nsubj 12,were
R4216 T13515 T13503 conj were,were
R4217 T13516 T13515 attr insertions,were
R4218 T13517 T13516 cc or,insertions
R4219 T13518 T13516 conj deletions,insertions
R4220 T13519 T13516 prep in,insertions
R4221 T13520 T13519 pobj CAST,in
R4222 T13521 T13522 punct (,File
R4223 T13522 T13503 parataxis File,were
R4224 T13523 T13522 amod Additional,File
R4225 T13524 T13522 nummod 4,File
R4226 T13525 T13522 punct ),File
R4227 T13526 T13503 punct .,were
R4228 T13528 T13529 predet All,insertions
R4229 T13529 T13531 nsubjpass insertions,located
R4230 T13530 T13529 nummod 12,insertions
R4231 T13532 T13529 cc or,insertions
R4232 T13533 T13529 conj deletions,insertions
R4233 T13534 T13531 auxpass were,located
R4234 T13535 T13531 prep within,located
R4235 T13536 T13537 nummod 5,UTRs
R4236 T13537 T13535 pobj UTRs,within
R4237 T13538 T13536 punct ',5
R4238 T13539 T13536 cc and,5
R4239 T13540 T13536 conj 3,5
R4240 T13541 T13540 punct ',3
R4241 T13542 T13531 punct .,located
R4242 T13544 T13545 compound Fifty,six
R4243 T13545 T13547 nummod six,SNP
R4244 T13546 T13545 punct -,six
R4245 T13547 T13549 nsubjpass SNP,identified
R4246 T13548 T13547 amod nonsynonomous,SNP
R4247 T13550 T13547 punct (,SNP
R4248 T13551 T13547 appos nsSNP,SNP
R4249 T13552 T13549 punct ),identified
R4250 T13553 T13549 auxpass were,identified
R4251 T13554 T13549 prep in,identified
R4252 T13555 T13556 nummod 14,genes
R4253 T13556 T13554 pobj genes,in
R4254 T13557 T13556 amod different,genes
R4255 T13558 T13559 punct (,File
R4256 T13559 T13549 parataxis File,identified
R4257 T13560 T13559 amod Additional,File
R4258 T13561 T13559 nummod 4,File
R4259 T13562 T13559 punct ),File
R4260 T13563 T13549 punct .,identified
R4261 T13565 T13566 nsubj PolyPhen,are
R4262 T13567 T13568 punct [,29
R4263 T13568 T13565 parataxis 29,PolyPhen
R4264 T13569 T13568 punct ],29
R4265 T13570 T13565 cc and,PolyPhen
R4266 T13571 T13565 conj SIFT,PolyPhen
R4267 T13572 T13573 punct [,30
R4268 T13573 T13571 parataxis 30,SIFT
R4269 T13574 T13573 punct ],30
R4270 T13575 T13576 compound software,programs
R4271 T13576 T13566 attr programs,are
R4272 T13577 T13576 acl designed,programs
R4273 T13578 T13579 aux to,identify
R4274 T13579 T13577 advcl identify,designed
R4275 T13580 T13579 dobj nsSNP,identify
R4276 T13581 T13582 dep which,alter
R4277 T13582 T13580 relcl alter,nsSNP
R4278 T13583 T13582 advmod potentially,alter
R4279 T13584 T13585 compound protein,function
R4280 T13585 T13582 dobj function,alter
R4281 T13586 T13579 prep by,identify
R4282 T13587 T13586 pcomp evaluating,by
R4283 T13588 T13589 amod evolutionary,conservation
R4284 T13589 T13587 dobj conservation,evaluating
R4285 T13590 T13587 prep at,evaluating
R4286 T13591 T13592 amod specific,residues
R4287 T13592 T13590 pobj residues,at
R4288 T13593 T13594 compound amino,acid
R4289 T13594 T13592 compound acid,residues
R4290 T13595 T13587 advcl using,evaluating
R4291 T13596 T13597 det a,alignment
R4292 T13597 T13595 dobj alignment,using
R4293 T13598 T13599 amod multiple,sequence
R4294 T13599 T13597 compound sequence,alignment
R4295 T13600 T13597 prep of,alignment
R4296 T13601 T13602 compound protein,sequences
R4297 T13602 T13600 pobj sequences,of
R4298 T13603 T13602 amod homologous,sequences
R4299 T13604 T13603 prep to,homologous
R4300 T13605 T13606 det the,query
R4301 T13606 T13604 pobj query,to
R4302 T13607 T13566 punct .,are
R4303 T13609 T13610 advmod When,applied
R4304 T13610 T13611 advcl applied,predicted
R4305 T13612 T13610 prep to,applied
R4306 T13613 T13614 poss our,set
R4307 T13614 T13612 pobj set,to
R4308 T13615 T13614 compound data,set
R4309 T13616 T13611 nsubj PolyPhen,predicted
R4310 T13617 T13616 punct ", ",PolyPhen
R4311 T13618 T13616 conj SIFT,PolyPhen
R4312 T13619 T13618 cc or,SIFT
R4313 T13620 T13621 det both,programs
R4314 T13621 T13618 conj programs,SIFT
R4315 T13622 T13623 mark that,alter
R4316 T13623 T13611 ccomp alter,predicted
R4317 T13624 T13625 quantmod 15,56
R4318 T13625 T13628 nummod 56,nsSNP
R4319 T13626 T13625 quantmod of,56
R4320 T13627 T13625 quantmod the,56
R4321 T13628 T13623 nsubj nsSNP,alter
R4322 T13629 T13628 prep in,nsSNP
R4323 T13630 T13631 nummod 9,genes
R4324 T13631 T13629 pobj genes,in
R4325 T13632 T13631 amod different,genes
R4326 T13633 T13623 aux would,alter
R4327 T13634 T13623 advmod possibly,alter
R4328 T13635 T13636 compound protein,function
R4329 T13636 T13623 dobj function,alter
R4330 T13637 T13638 punct (,Table
R4331 T13638 T13611 parataxis Table,predicted
R4332 T13639 T13638 nummod 7,Table
R4333 T13640 T13638 punct ),Table
R4334 T13641 T13611 punct .,predicted