PMC:1448208 / 6119-6532 4 Projects
Annnotations
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T4113 | 0-8 | RB | denotes | Recently |
| T4115 | 8-10 | , | denotes | , |
| T4116 | 10-11 | DT | denotes | a |
| T4118 | 12-13 | NN | denotes | N |
| T4120 | 13-14 | HYPH | denotes | - |
| T4119 | 14-19 | NN | denotes | ethyl |
| T4121 | 19-20 | HYPH | denotes | - |
| T4122 | 20-21 | NN | denotes | N |
| T4123 | 21-22 | HYPH | denotes | - |
| T4117 | 22-33 | NN | denotes | nitrosourea |
| T4125 | 34-35 | -LRB- | denotes | ( |
| T4126 | 35-38 | NN | denotes | ENU |
| T4127 | 38-39 | -RRB- | denotes | ) |
| T4128 | 39-40 | HYPH | denotes | - |
| T4124 | 40-47 | VBN | denotes | induced |
| T4130 | 48-54 | NN | denotes | mutant |
| T4129 | 55-60 | NN | denotes | mouse |
| T4131 | 61-65 | WDT | denotes | that |
| T4133 | 66-80 | RB | denotes | phenotypically |
| T4132 | 81-90 | VBZ | denotes | resembles |
| T4134 | 91-96 | JJ | denotes | human |
| T4135 | 97-101 | NN | denotes | MSUD |
| T4136 | 102-105 | VBZ | denotes | has |
| T4137 | 106-110 | VBN | denotes | been |
| T4114 | 111-120 | VBN | denotes | described |
| T4138 | 121-122 | -LRB- | denotes | [ |
| T4139 | 122-124 | CD | denotes | 20 |
| T4140 | 124-125 | -RRB- | denotes | ] |
| T4141 | 125-126 | . | denotes | . |
| T4142 | 126-295 | sentence | denotes | However, the mutation in this model disrupts a splice site in the mitochondrial branched-chain aminotransferase (BCAT) gene, not in BCKDH, the deficient enzyme in MSUD. |
| T4143 | 127-134 | RB | denotes | However |
| T4145 | 134-136 | , | denotes | , |
| T4146 | 136-139 | DT | denotes | the |
| T4147 | 140-148 | NN | denotes | mutation |
| T4148 | 149-151 | IN | denotes | in |
| T4149 | 152-156 | DT | denotes | this |
| T4150 | 157-162 | NN | denotes | model |
| T4144 | 163-171 | VBZ | denotes | disrupts |
| T4151 | 172-173 | DT | denotes | a |
| T4153 | 174-180 | NN | denotes | splice |
| T4152 | 181-185 | NN | denotes | site |
| T4154 | 186-188 | IN | denotes | in |
| T4155 | 189-192 | DT | denotes | the |
| T4157 | 193-206 | JJ | denotes | mitochondrial |
| T4158 | 207-215 | VBN | denotes | branched |
| T4160 | 215-216 | HYPH | denotes | - |
| T4159 | 216-221 | NN | denotes | chain |
| T4156 | 222-238 | NN | denotes | aminotransferase |
| T4162 | 239-240 | -LRB- | denotes | ( |
| T4163 | 240-244 | NN | denotes | BCAT |
| T4164 | 244-245 | -RRB- | denotes | ) |
| T4161 | 246-250 | NN | denotes | gene |
| T4165 | 250-252 | , | denotes | , |
| T4166 | 252-255 | RB | denotes | not |
| T4167 | 256-258 | IN | denotes | in |
| T4168 | 259-264 | NN | denotes | BCKDH |
| T4169 | 264-266 | , | denotes | , |
| T4170 | 266-269 | DT | denotes | the |
| T4172 | 270-279 | JJ | denotes | deficient |
| T4171 | 280-286 | NN | denotes | enzyme |
| T4173 | 287-289 | IN | denotes | in |
| T4174 | 290-294 | NN | denotes | MSUD |
| T4175 | 294-295 | . | denotes | . |
| T4176 | 295-413 | sentence | denotes | Because the mutation is not in BCKDH, the validity of this mutant mouse line for modeling human MSUD is questionable. |
| T4177 | 296-303 | IN | denotes | Because |
| T4179 | 304-307 | DT | denotes | the |
| T4180 | 308-316 | NN | denotes | mutation |
| T4178 | 317-319 | VBZ | denotes | is |
| T4182 | 320-323 | RB | denotes | not |
| T4183 | 324-326 | IN | denotes | in |
| T4184 | 327-332 | NN | denotes | BCKDH |
| T4185 | 332-334 | , | denotes | , |
| T4186 | 334-337 | DT | denotes | the |
| T4187 | 338-346 | NN | denotes | validity |
| T4188 | 347-349 | IN | denotes | of |
| T4189 | 350-354 | DT | denotes | this |
| T4191 | 355-361 | NN | denotes | mutant |
| T4192 | 362-367 | NN | denotes | mouse |
| T4190 | 368-372 | NN | denotes | line |
| T4193 | 373-376 | IN | denotes | for |
| T4194 | 377-385 | VBG | denotes | modeling |
| T4196 | 386-391 | JJ | denotes | human |
| T4195 | 392-396 | NN | denotes | MSUD |
| T4181 | 397-399 | VBZ | denotes | is |
| T4197 | 400-412 | JJ | denotes | questionable |
| T4198 | 412-413 | . | denotes | . |
| R1065 | T4162 | T4156 | punct | (,aminotransferase |
| R1067 | T4163 | T4156 | appos | BCAT,aminotransferase |
| R1068 | T4164 | T4161 | punct | ),gene |
| R1069 | T4165 | T4154 | punct | ", ",in |
| R1070 | T4166 | T4154 | neg | not,in |
| R1071 | T4167 | T4154 | prep | in,in |
| R1073 | T4168 | T4167 | pobj | BCKDH,in |
| R1074 | T4169 | T4168 | punct | ", ",BCKDH |
| R1076 | T4170 | T4171 | det | the,enzyme |
| R1077 | T4171 | T4168 | appos | enzyme,BCKDH |
| R1078 | T4172 | T4171 | amod | deficient,enzyme |
| R1079 | T4173 | T4171 | prep | in,enzyme |
| R1081 | T4174 | T4173 | pobj | MSUD,in |
| R1082 | T4175 | T4144 | punct | .,disrupts |
| R1084 | T4177 | T4178 | mark | Because,is |
| R1085 | T4178 | T4181 | advcl | is,is |
| R1087 | T4179 | T4180 | det | the,mutation |
| R1088 | T4180 | T4178 | nsubj | mutation,is |
| R1089 | T4182 | T4178 | neg | not,is |
| R1091 | T4183 | T4178 | prep | in,is |
| R1092 | T4184 | T4183 | pobj | BCKDH,in |
| R1093 | T4185 | T4181 | punct | ", ",is |
| R1094 | T4186 | T4187 | det | the,validity |
| R1095 | T4187 | T4181 | nsubj | validity,is |
| R1097 | T4188 | T4187 | prep | of,validity |
| R1098 | T4189 | T4190 | det | this,line |
| R1099 | T4190 | T4188 | pobj | line,of |
| R1100 | T4191 | T4190 | compound | mutant,line |
| R1102 | T4192 | T4190 | compound | mouse,line |
| R1103 | T4193 | T4187 | prep | for,validity |
| R1104 | T4194 | T4195 | amod | modeling,MSUD |
| R1106 | T4195 | T4193 | pobj | MSUD,for |
| R1107 | T4196 | T4195 | amod | human,MSUD |
| R1108 | T4197 | T4181 | acomp | questionable,is |
| R1110 | T4198 | T4181 | punct | .,is |
| R1212 | T4113 | T4114 | advmod | Recently,described |
| R1217 | T4115 | T4114 | punct | ", ",described |
| R1222 | T4116 | T4117 | det | a,nitrosourea |
| R1227 | T4117 | T4124 | npadvmod | nitrosourea,induced |
| R1231 | T4118 | T4119 | compound | N,ethyl |
| R1235 | T4119 | T4117 | compound | ethyl,nitrosourea |
| R1239 | T4120 | T4119 | punct | -,ethyl |
| R1243 | T4121 | T4117 | punct | -,nitrosourea |
| R1247 | T4122 | T4117 | compound | N,nitrosourea |
| R1252 | T4123 | T4117 | punct | -,nitrosourea |
| R1256 | T4124 | T4129 | amod | induced,mouse |
| R1258 | T4125 | T4117 | punct | (,nitrosourea |
| R1259 | T4126 | T4117 | appos | ENU,nitrosourea |
| R1260 | T4127 | T4124 | punct | ),induced |
| R1261 | T4128 | T4124 | punct | -,induced |
| R1262 | T4129 | T4114 | nsubjpass | mouse,described |
| R1263 | T4130 | T4129 | compound | mutant,mouse |
| R1264 | T4131 | T4132 | dep | that,resembles |
| R1265 | T4132 | T4129 | relcl | resembles,mouse |
| R1266 | T4133 | T4132 | advmod | phenotypically,resembles |
| R1267 | T4134 | T4135 | amod | human,MSUD |
| R1268 | T4135 | T4132 | dobj | MSUD,resembles |
| R1269 | T4136 | T4114 | aux | has,described |
| R1270 | T4137 | T4114 | auxpass | been,described |
| R1271 | T4138 | T4139 | punct | [,20 |
| R1272 | T4139 | T4114 | parataxis | 20,described |
| R1273 | T4140 | T4139 | punct | ],20 |
| R1274 | T4141 | T4114 | punct | .,described |
| R1275 | T4143 | T4144 | advmod | However,disrupts |
| R1276 | T4145 | T4144 | punct | ", ",disrupts |
| R1277 | T4146 | T4147 | det | the,mutation |
| R1278 | T4147 | T4144 | nsubj | mutation,disrupts |
| R1279 | T4148 | T4147 | prep | in,mutation |
| R1280 | T4149 | T4150 | det | this,model |
| R1281 | T4150 | T4148 | pobj | model,in |
| R1282 | T4151 | T4152 | det | a,site |
| R1283 | T4152 | T4144 | dobj | site,disrupts |
| R1284 | T4153 | T4152 | compound | splice,site |
| R1285 | T4154 | T4152 | prep | in,site |
| R1286 | T4155 | T4156 | det | the,aminotransferase |
| R1287 | T4156 | T4161 | nmod | aminotransferase,gene |
| R1288 | T4157 | T4156 | amod | mitochondrial,aminotransferase |
| R1289 | T4158 | T4159 | amod | branched,chain |
| R1290 | T4159 | T4156 | nmod | chain,aminotransferase |
| R1291 | T4160 | T4159 | punct | -,chain |
| R1292 | T4161 | T4154 | pobj | gene,in |
