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PMC:1448208 / 17342-17865 JSONTXT 4 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T10564 0-9 RB denotes Correctly
T10565 10-18 VBN denotes targeted
T10567 19-21 NN denotes ES
T10566 22-27 NNS denotes cells
T10569 28-32 VBD denotes were
T10568 33-46 VBN denotes microinjected
T10570 47-51 IN denotes into
T10571 52-63 NNS denotes blastocysts
T10572 64-66 TO denotes to
T10573 67-74 VB denotes produce
T10574 75-83 JJ denotes chimeric
T10575 84-88 NNS denotes mice
T10576 88-89 . denotes .
T10577 89-127 sentence denotes Chimerics were bred to C57BL/6J mice.
T10578 90-99 NNS denotes Chimerics
T10580 100-104 VBD denotes were
T10579 105-109 VBN denotes bred
T10581 110-112 IN denotes to
T10582 113-118 NN denotes C57BL
T10584 118-119 HYPH denotes /
T10583 119-121 NN denotes 6J
T10585 122-126 NNS denotes mice
T10586 126-127 . denotes .
T10587 127-293 sentence denotes Following germline transmission of the targeted allele, heterozygous mice were interbred to produce wild type (+/+), heterozygous (+/-) and homozygous (-/-) animals.
T10588 128-137 VBG denotes Following
T10590 138-146 NN denotes germline
T10591 147-159 NN denotes transmission
T10592 160-162 IN denotes of
T10593 163-166 DT denotes the
T10595 167-175 VBN denotes targeted
T10594 176-182 NN denotes allele
T10596 182-184 , denotes ,
T10597 184-196 JJ denotes heterozygous
T10598 197-201 NNS denotes mice
T10599 202-206 VBD denotes were
T10589 207-216 VBN denotes interbred
T10600 217-219 TO denotes to
T10601 220-227 VB denotes produce
T10602 228-232 JJ denotes wild
T10603 233-237 NN denotes type
T10605 238-239 -LRB- denotes (
T10607 239-240 SYM denotes +
T10608 240-241 HYPH denotes /
T10606 241-242 SYM denotes +
T10609 242-243 -RRB- denotes )
T10610 243-245 , denotes ,
T10611 245-257 JJ denotes heterozygous
T10612 258-259 -LRB- denotes (
T10614 259-260 SYM denotes +
T10615 260-261 HYPH denotes /
T10613 261-262 SYM denotes -
T10616 262-263 -RRB- denotes )
T10617 264-267 CC denotes and
T10618 268-278 JJ denotes homozygous
T10619 279-280 -LRB- denotes (
T10621 280-281 SYM denotes -
T10622 281-282 HYPH denotes /
T10620 282-283 SYM denotes -
T10623 283-284 -RRB- denotes )
T10604 285-292 NNS denotes animals
T10624 292-293 . denotes .
T10625 293-340 sentence denotes Mice were genotyped by Southern blot analysis.
T10626 294-298 NNS denotes Mice
T10628 299-303 VBD denotes were
T10627 304-313 VBN denotes genotyped
T10629 314-316 IN denotes by
T10630 317-325 NNP denotes Southern
T10631 326-330 NN denotes blot
T10632 331-339 NN denotes analysis
T10633 339-340 . denotes .
T10634 340-523 sentence denotes The Exon 6 specific probe hybridized to only a ~16 kb BglI restriction fragment in +/+ mice, a ~11 kb BglI fragment in -/- mice, and to both of these fragments in +/- mice (Fig. 1B).
T10635 341-344 DT denotes The
T10637 345-349 NN denotes Exon
T10639 350-351 CD denotes 6
T10638 352-360 JJ denotes specific
T10636 361-366 NN denotes probe
T10640 367-377 VBN denotes hybridized
T10641 378-380 IN denotes to
T10642 381-385 RB denotes only
T10644 386-387 DT denotes a
T10645 388-389 SYM denotes ~
T10646 389-391 CD denotes 16
T10647 392-394 NN denotes kb
T10648 395-399 NN denotes BglI
T10649 400-411 NN denotes restriction
T10643 412-420 NN denotes fragment
T10650 421-423 IN denotes in
T10651 424-425 SYM denotes +
T10653 425-426 HYPH denotes /
T10652 426-427 SYM denotes +
T10654 428-432 NNS denotes mice
T10655 432-434 , denotes ,
T10656 434-435 DT denotes a
T10658 436-437 SYM denotes ~
T10659 437-439 CD denotes 11
T10660 440-442 NN denotes kb
T10661 443-447 NN denotes BglI
T10657 448-456 NN denotes fragment
T10662 457-459 IN denotes in
T10663 460-461 SYM denotes -
T10665 461-462 HYPH denotes /
T10664 462-463 SYM denotes -
T10666 464-468 NNS denotes mice
T10667 468-470 , denotes ,
T10668 470-473 CC denotes and
T10669 474-476 IN denotes to
T10670 477-481 DT denotes both
T10671 482-484 IN denotes of
T10672 485-490 DT denotes these
T10673 491-500 NNS denotes fragments
T10674 501-503 IN denotes in
T10675 504-505 SYM denotes +
T10677 505-506 HYPH denotes /
T10676 506-507 SYM denotes -
T10678 508-512 NNS denotes mice
T10679 513-514 -LRB- denotes (
T10681 514-518 NN denotes Fig.
T10680 519-521 NN denotes 1B
T10682 521-522 -RRB- denotes )
T10683 522-523 . denotes .
R2959 T10564 T10565 advmod Correctly,targeted
R2960 T10565 T10566 amod targeted,cells
R2961 T10566 T10568 nsubjpass cells,microinjected
R2962 T10567 T10566 compound ES,cells
R2963 T10569 T10568 auxpass were,microinjected
R2964 T10570 T10568 prep into,microinjected
R2965 T10571 T10570 pobj blastocysts,into
R2966 T10572 T10573 aux to,produce
R2967 T10573 T10568 advcl produce,microinjected
R2968 T10574 T10575 amod chimeric,mice
R2969 T10575 T10573 dobj mice,produce
R2970 T10576 T10568 punct .,microinjected
R2971 T10578 T10579 nsubjpass Chimerics,bred
R2972 T10580 T10579 auxpass were,bred
R2973 T10581 T10579 prep to,bred
R2974 T10582 T10583 compound C57BL,6J
R2975 T10583 T10585 compound 6J,mice
R2976 T10584 T10583 punct /,6J
R2977 T10585 T10581 pobj mice,to
R2978 T10586 T10579 punct .,bred
R2979 T10588 T10589 prep Following,interbred
R2980 T10590 T10591 compound germline,transmission
R2981 T10591 T10588 pobj transmission,Following
R2982 T10592 T10591 prep of,transmission
R2983 T10593 T10594 det the,allele
R2984 T10594 T10592 pobj allele,of
R2985 T10595 T10594 amod targeted,allele
R2986 T10596 T10589 punct ", ",interbred
R2987 T10597 T10598 amod heterozygous,mice
R2988 T10598 T10589 nsubjpass mice,interbred
R2989 T10599 T10589 auxpass were,interbred
R2990 T10600 T10601 aux to,produce
R2991 T10601 T10589 advcl produce,interbred
R2992 T10602 T10603 amod wild,type
R2993 T10603 T10604 nmod type,animals
R2994 T10604 T10601 dobj animals,produce
R2995 T10605 T10606 punct (,+
R2996 T10606 T10603 punct +,type
R2997 T10607 T10606 punct +,+
R2998 T10608 T10606 punct /,+
R2999 T10609 T10606 punct ),+
R3000 T10610 T10603 punct ", ",type
R3001 T10611 T10603 conj heterozygous,type
R3002 T10612 T10613 punct (,-
R3003 T10613 T10611 punct -,heterozygous
R3004 T10614 T10613 punct +,-
R3005 T10615 T10613 punct /,-
R3006 T10616 T10613 punct ),-
R3007 T10617 T10611 cc and,heterozygous
R3008 T10618 T10611 conj homozygous,heterozygous
R3009 T10619 T10620 punct (,-
R3010 T10620 T10618 punct -,homozygous
R3011 T10621 T10620 punct -,-
R3012 T10622 T10620 punct /,-
R3013 T10623 T10620 punct ),-
R3014 T10624 T10589 punct .,interbred
R3015 T10626 T10627 nsubjpass Mice,genotyped
R3016 T10628 T10627 auxpass were,genotyped
R3017 T10629 T10627 prep by,genotyped
R3018 T10630 T10631 compound Southern,blot
R3019 T10631 T10632 compound blot,analysis
R3020 T10632 T10629 pobj analysis,by
R3021 T10633 T10627 punct .,genotyped
R3022 T10635 T10636 det The,probe
R3023 T10636 T10640 nsubj probe,hybridized
R3024 T10637 T10638 npadvmod Exon,specific
R3025 T10638 T10636 amod specific,probe
R3026 T10639 T10637 nummod 6,Exon
R3027 T10641 T10640 prep to,hybridized
R3028 T10642 T10643 advmod only,fragment
R3029 T10643 T10641 pobj fragment,to
R3030 T10644 T10643 det a,fragment
R3031 T10645 T10646 punct ~,16
R3032 T10646 T10647 nummod 16,kb
R3033 T10647 T10643 compound kb,fragment
R3034 T10648 T10643 compound BglI,fragment
R3035 T10649 T10643 compound restriction,fragment
R3036 T10650 T10643 prep in,fragment
R3037 T10651 T10652 punct +,+
R3038 T10652 T10654 punct +,mice
R3039 T10653 T10652 punct /,+
R3040 T10654 T10650 pobj mice,in
R3041 T10655 T10643 punct ", ",fragment
R3042 T10656 T10657 det a,fragment
R3043 T10657 T10643 appos fragment,fragment
R3044 T10658 T10659 punct ~,11
R3045 T10659 T10660 nummod 11,kb
R3046 T10660 T10657 compound kb,fragment
R3047 T10661 T10657 compound BglI,fragment
R3048 T10662 T10657 prep in,fragment
R3049 T10663 T10664 punct -,-
R3050 T10664 T10666 punct -,mice
R3051 T10665 T10664 punct /,-
R3052 T10666 T10662 pobj mice,in
R3053 T10667 T10641 punct ", ",to
R3054 T10668 T10641 cc and,to
R3055 T10669 T10641 conj to,to
R3056 T10670 T10669 pobj both,to
R3057 T10671 T10670 prep of,both
R3058 T10672 T10673 det these,fragments
R3059 T10673 T10671 pobj fragments,of
R3060 T10674 T10670 prep in,both
R3061 T10675 T10676 punct +,-
R3062 T10676 T10678 punct -,mice
R3063 T10677 T10676 punct /,-
R3064 T10678 T10674 pobj mice,in
R3065 T10679 T10680 punct (,1B
R3066 T10680 T10640 parataxis 1B,hybridized
R3067 T10681 T10680 compound Fig.,1B
R3068 T10682 T10680 punct ),1B
R3069 T10683 T10640 punct .,hybridized