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PMC:1440874 / 44219-45109 JSONTXT 5 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T9946 0-7 DT denotes Another
T9948 8-18 JJ denotes surprising
T9947 19-26 NN denotes finding
T9950 27-29 IN denotes of
T9951 30-34 DT denotes this
T9952 35-40 NN denotes study
T9949 41-43 VBZ denotes is
T9953 44-48 IN denotes that
T9955 48-50 , denotes ,
T9956 50-52 IN denotes in
T9957 53-60 NN denotes carrier
T9959 61-67 JJ denotes female
T9958 68-75 NNS denotes embryos
T9960 75-77 , denotes ,
T9961 77-78 DT denotes a
T9963 79-89 RB denotes paternally
T9964 90-99 VBN denotes inherited
T9965 100-107 NN denotes Atrx WT
T9962 108-114 NN denotes allele
T9954 115-122 VBZ denotes appears
T9966 123-125 TO denotes to
T9967 126-132 VB denotes escape
T9968 133-136 DT denotes the
T9969 137-144 NN denotes process
T9970 145-147 IN denotes of
T9971 148-157 VBN denotes imprinted
T9973 158-159 NN denotes X
T9974 159-160 HYPH denotes -
T9972 160-172 NN denotes inactivation
T9975 172-174 , denotes ,
T9976 174-179 WDT denotes which
T9978 180-190 RB denotes ordinarily
T9977 191-199 VBZ denotes silences
T9979 200-203 DT denotes the
T9981 204-206 NN denotes Xp
T9980 207-217 NN denotes chromosome
T9982 218-220 IN denotes in
T9983 221-224 DT denotes the
T9985 225-239 JJ denotes extraembryonic
T9984 240-251 NN denotes compartment
T9986 252-254 IN denotes of
T9987 255-261 JJ denotes female
T9989 262-268 JJ denotes murine
T9988 269-276 NNS denotes tissues
T9990 277-278 -LRB- denotes [
T9991 278-280 CD denotes 18
T9992 280-281 -RRB- denotes ]
T9993 281-282 . denotes .
T9994 282-466 sentence denotes Silencing of the Atrx WT allele on Xp should render these females null for Atrx in the extraembryonic tissues, since the normally active Xm chromosome carries the Atrx Δ18Δneo allele.
T9995 283-292 NN denotes Silencing
T9997 293-295 IN denotes of
T9998 296-299 DT denotes the
T10000 300-307 NN denotes Atrx WT
T9999 308-314 NN denotes allele
T10001 315-317 IN denotes on
T10002 318-320 NN denotes Xp
T10003 321-327 MD denotes should
T9996 328-334 VB denotes render
T10004 335-340 DT denotes these
T10005 341-348 NNS denotes females
T10006 349-353 JJ denotes null
T10007 354-357 IN denotes for
T10008 358-362 NN denotes Atrx
T10009 363-365 IN denotes in
T10010 366-369 DT denotes the
T10012 370-384 JJ denotes extraembryonic
T10011 385-392 NNS denotes tissues
T10013 392-394 , denotes ,
T10014 394-399 IN denotes since
T10016 400-403 DT denotes the
T10018 404-412 RB denotes normally
T10019 413-419 JJ denotes active
T10020 420-422 NN denotes Xm
T10017 423-433 NN denotes chromosome
T10015 434-441 VBZ denotes carries
T10021 442-445 DT denotes the
T10023 446-458 NN denotes Atrx Δ18Δneo
T10022 459-465 NN denotes allele
T10024 465-466 . denotes .
T10025 466-572 sentence denotes Although not phenotypically normal, some Atrx carrier females developed to term and went on to reproduce.
T10026 467-475 IN denotes Although
T10028 476-479 RB denotes not
T10029 480-494 RB denotes phenotypically
T10027 495-501 JJ denotes normal
T10031 501-503 , denotes ,
T10032 503-507 DT denotes some
T10034 508-512 NN denotes Atrx
T10035 513-520 NN denotes carrier
T10033 521-528 NNS denotes females
T10030 529-538 VBD denotes developed
T10036 539-541 IN denotes to
T10037 542-546 NN denotes term
T10038 547-550 CC denotes and
T10039 551-555 VBD denotes went
T10040 556-558 RP denotes on
T10041 559-561 TO denotes to
T10042 562-571 VB denotes reproduce
T10043 571-572 . denotes .
T10044 572-890 sentence denotes Thus, the failure to correctly silence the paternally derived Atrx WT allele in the extraembryonic tissues of carrier females is consistent with our observations that in Atrxnull males, the Atrx protein plays an essential role in the development of the trophoblast and is necessary for survival in utero in the mouse.
T10045 573-577 RB denotes Thus
T10047 577-579 , denotes ,
T10048 579-582 DT denotes the
T10049 583-590 NN denotes failure
T10050 591-593 TO denotes to
T10052 594-603 RB denotes correctly
T10051 604-611 VB denotes silence
T10053 612-615 DT denotes the
T10055 616-626 RB denotes paternally
T10056 627-634 VBN denotes derived
T10057 635-642 NN denotes Atrx WT
T10054 643-649 NN denotes allele
T10058 650-652 IN denotes in
T10059 653-656 DT denotes the
T10061 657-671 JJ denotes extraembryonic
T10060 672-679 NNS denotes tissues
T10062 680-682 IN denotes of
T10063 683-690 NN denotes carrier
T10064 691-698 NNS denotes females
T10046 699-701 VBZ denotes is
T10065 702-712 JJ denotes consistent
T10066 713-717 IN denotes with
T10067 718-721 PRP$ denotes our
T10068 722-734 NNS denotes observations
T10069 735-739 IN denotes that
T10071 740-742 IN denotes in
T10072 743-751 JJ denotes Atrxnull
T10073 752-757 NNS denotes males
T10074 757-759 , denotes ,
T10075 759-762 DT denotes the
T10077 763-767 NN denotes Atrx
T10076 768-775 NN denotes protein
T10070 776-781 VBZ denotes plays
T10078 782-784 DT denotes an
T10080 785-794 JJ denotes essential
T10079 795-799 NN denotes role
T10081 800-802 IN denotes in
T10082 803-806 DT denotes the
T10083 807-818 NN denotes development
T10084 819-821 IN denotes of
T10085 822-825 DT denotes the
T10086 826-837 NN denotes trophoblast
T10087 838-841 CC denotes and
T10088 842-844 VBZ denotes is
T10089 845-854 JJ denotes necessary
T10090 855-858 IN denotes for
T10091 859-867 NN denotes survival
T10092 868-870 FW denotes in
T10093 871-876 FW denotes utero
T10094 877-879 IN denotes in
T10095 880-883 DT denotes the
T10096 884-889 NN denotes mouse
T10097 889-890 . denotes .
R5939 T9946 T9947 det Another,finding
R5940 T9947 T9949 nsubj finding,is
R5941 T9948 T9947 amod surprising,finding
R5942 T9950 T9947 prep of,finding
R5943 T9951 T9952 det this,study
R5944 T9952 T9950 pobj study,of
R5945 T9953 T9954 mark that,appears
R5946 T9954 T9949 ccomp appears,is
R5947 T9955 T9954 punct ", ",appears
R5948 T9956 T9954 prep in,appears
R5949 T9957 T9958 nmod carrier,embryos
R5950 T9958 T9956 pobj embryos,in
R5951 T9959 T9958 amod female,embryos
R5952 T9960 T9954 punct ", ",appears
R5953 T9961 T9962 det a,allele
R5954 T9962 T9954 nsubj allele,appears
R5955 T9963 T9964 advmod paternally,inherited
R5956 T9964 T9962 amod inherited,allele
R5957 T9965 T9962 compound Atrx WT,allele
R5958 T9966 T9967 aux to,escape
R5959 T9967 T9954 xcomp escape,appears
R5960 T9968 T9969 det the,process
R5961 T9969 T9967 dobj process,escape
R5962 T9970 T9969 prep of,process
R5963 T9971 T9972 amod imprinted,inactivation
R5964 T9972 T9970 pobj inactivation,of
R5965 T9973 T9972 compound X,inactivation
R5966 T9974 T9972 punct -,inactivation
R5967 T9975 T9969 punct ", ",process
R5968 T9976 T9977 dep which,silences
R5969 T9977 T9969 relcl silences,process
R5970 T9978 T9977 advmod ordinarily,silences
R5971 T9979 T9980 det the,chromosome
R5972 T9980 T9977 dobj chromosome,silences
R5973 T9981 T9980 compound Xp,chromosome
R5974 T9982 T9977 prep in,silences
R5975 T9983 T9984 det the,compartment
R5976 T9984 T9982 pobj compartment,in
R5977 T9985 T9984 amod extraembryonic,compartment
R5978 T9986 T9984 prep of,compartment
R5979 T9987 T9988 amod female,tissues
R5980 T9988 T9986 pobj tissues,of
R5981 T9989 T9988 amod murine,tissues
R5982 T9990 T9991 punct [,18
R5983 T9991 T9949 parataxis 18,is
R5984 T9992 T9991 punct ],18
R5985 T9993 T9949 punct .,is
R5986 T9995 T9996 nsubj Silencing,render
R5987 T9997 T9995 prep of,Silencing
R5988 T9998 T9999 det the,allele
R5989 T9999 T9997 pobj allele,of
R5990 T10000 T9999 compound Atrx WT,allele
R5991 T10001 T9995 prep on,Silencing
R5992 T10002 T10001 pobj Xp,on
R5993 T10003 T9996 aux should,render
R5994 T10004 T10005 det these,females
R5995 T10005 T9996 dobj females,render
R5996 T10006 T9996 oprd null,render
R5997 T10007 T10006 prep for,null
R5998 T10008 T10007 pobj Atrx,for
R5999 T10009 T9996 prep in,render
R6000 T10010 T10011 det the,tissues
R6001 T10011 T10009 pobj tissues,in
R6002 T10012 T10011 amod extraembryonic,tissues
R6003 T10013 T9996 punct ", ",render
R6004 T10014 T10015 mark since,carries
R6005 T10015 T9996 advcl carries,render
R6006 T10016 T10017 det the,chromosome
R6007 T10017 T10015 nsubj chromosome,carries
R6008 T10018 T10019 advmod normally,active
R6009 T10019 T10017 amod active,chromosome
R6010 T10020 T10017 compound Xm,chromosome
R6011 T10021 T10022 det the,allele
R6012 T10022 T10015 dobj allele,carries
R6013 T10023 T10022 compound Atrx Δ18Δneo,allele
R6014 T10024 T9996 punct .,render
R6015 T10026 T10027 mark Although,normal
R6016 T10027 T10030 advcl normal,developed
R6017 T10028 T10027 neg not,normal
R6018 T10029 T10027 advmod phenotypically,normal
R6019 T10031 T10030 punct ", ",developed
R6020 T10032 T10033 det some,females
R6021 T10033 T10030 nsubj females,developed
R6022 T10034 T10033 compound Atrx,females
R6023 T10035 T10033 compound carrier,females
R6024 T10036 T10030 prep to,developed
R6025 T10037 T10036 pobj term,to
R6026 T10038 T10030 cc and,developed
R6027 T10039 T10030 conj went,developed
R6028 T10040 T10039 prt on,went
R6029 T10041 T10042 aux to,reproduce
R6030 T10042 T10039 xcomp reproduce,went
R6031 T10043 T10030 punct .,developed
R6032 T10045 T10046 advmod Thus,is
R6033 T10047 T10046 punct ", ",is
R6034 T10048 T10049 det the,failure
R6035 T10049 T10046 nsubj failure,is
R6036 T10050 T10051 aux to,silence
R6037 T10051 T10049 acl silence,failure
R6038 T10052 T10051 advmod correctly,silence
R6039 T10053 T10054 det the,allele
R6040 T10054 T10051 dobj allele,silence
R6041 T10055 T10056 advmod paternally,derived
R6042 T10056 T10054 amod derived,allele
R6043 T10057 T10054 compound Atrx WT,allele
R6044 T10058 T10054 prep in,allele
R6045 T10059 T10060 det the,tissues
R6046 T10060 T10058 pobj tissues,in
R6047 T10061 T10060 amod extraembryonic,tissues
R6048 T10062 T10060 prep of,tissues
R6049 T10063 T10064 compound carrier,females
R6050 T10064 T10062 pobj females,of
R6051 T10065 T10046 acomp consistent,is
R6052 T10066 T10065 prep with,consistent
R6053 T10067 T10068 poss our,observations
R6054 T10068 T10066 pobj observations,with
R6055 T10069 T10070 mark that,plays
R6056 T10070 T10068 acl plays,observations
R6057 T10071 T10070 prep in,plays
R6058 T10072 T10073 amod Atrxnull,males
R6059 T10073 T10071 pobj males,in
R6060 T10074 T10070 punct ", ",plays
R6061 T10075 T10076 det the,protein
R6062 T10076 T10070 nsubj protein,plays
R6063 T10077 T10076 compound Atrx,protein
R6064 T10078 T10079 det an,role
R6065 T10079 T10070 dobj role,plays
R6066 T10080 T10079 amod essential,role
R6067 T10081 T10070 prep in,plays
R6068 T10082 T10083 det the,development
R6069 T10083 T10081 pobj development,in
R6070 T10084 T10083 prep of,development
R6071 T10085 T10086 det the,trophoblast
R6072 T10086 T10084 pobj trophoblast,of
R6073 T10087 T10070 cc and,plays
R6074 T10088 T10070 conj is,plays
R6075 T10089 T10088 acomp necessary,is
R6076 T10090 T10089 prep for,necessary
R6077 T10091 T10090 pobj survival,for
R6078 T10092 T10093 advmod in,utero
R6079 T10093 T10091 advmod utero,survival
R6080 T10094 T10088 prep in,is
R6081 T10095 T10096 det the,mouse
R6082 T10096 T10094 pobj mouse,in
R6083 T10097 T10046 punct .,is