| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T722 |
0-3 |
NN |
denotes |
ATR |
| T724 |
3-4 |
HYPH |
denotes |
- |
| T723 |
4-5 |
NN |
denotes |
X |
| T725 |
6-14 |
NN |
denotes |
syndrome |
| T726 |
15-17 |
VBZ |
denotes |
is |
| T727 |
18-19 |
DT |
denotes |
a |
| T729 |
20-26 |
JJ |
denotes |
severe |
| T730 |
26-28 |
, |
denotes |
, |
| T731 |
28-42 |
JJ |
denotes |
nonprogressive |
| T728 |
43-47 |
NN |
denotes |
form |
| T732 |
48-50 |
IN |
denotes |
of |
| T733 |
51-52 |
NN |
denotes |
X |
| T735 |
52-53 |
HYPH |
denotes |
- |
| T734 |
53-59 |
VBN |
denotes |
linked |
| T737 |
60-66 |
JJ |
denotes |
mental |
| T736 |
67-78 |
NN |
denotes |
retardation |
| T738 |
79-83 |
WDT |
denotes |
that |
| T740 |
84-86 |
VBZ |
denotes |
is |
| T741 |
87-97 |
RB |
denotes |
frequently |
| T739 |
98-108 |
VBN |
denotes |
associated |
| T742 |
109-113 |
IN |
denotes |
with |
| T743 |
114-122 |
JJ |
denotes |
multiple |
| T745 |
123-133 |
JJ |
denotes |
congenital |
| T744 |
134-147 |
NNS |
denotes |
abnormalities |
| T746 |
148-149 |
-LRB- |
denotes |
[ |
| T747 |
149-150 |
CD |
denotes |
1 |
| T748 |
150-151 |
-RRB- |
denotes |
] |
| T749 |
151-152 |
. |
denotes |
. |
| T750 |
152-401 |
sentence |
denotes |
It is usually associated with a mild form of α-thalassaemia, caused by reduced expression of structurally intact α-globin genes, and characterised by the presence of β-globin tetramers (haemoglobin H inclusion bodies) in peripheral red blood cells. |
| T751 |
153-155 |
PRP |
denotes |
It |
| T753 |
156-158 |
VBZ |
denotes |
is |
| T754 |
159-166 |
RB |
denotes |
usually |
| T752 |
167-177 |
VBN |
denotes |
associated |
| T755 |
178-182 |
IN |
denotes |
with |
| T756 |
183-184 |
DT |
denotes |
a |
| T758 |
185-189 |
JJ |
denotes |
mild |
| T757 |
190-194 |
NN |
denotes |
form |
| T759 |
195-197 |
IN |
denotes |
of |
| T760 |
198-199 |
NN |
denotes |
α |
| T762 |
199-200 |
HYPH |
denotes |
- |
| T761 |
200-212 |
NN |
denotes |
thalassaemia |
| T763 |
212-214 |
, |
denotes |
, |
| T764 |
214-220 |
VBN |
denotes |
caused |
| T765 |
221-223 |
IN |
denotes |
by |
| T766 |
224-231 |
VBN |
denotes |
reduced |
| T767 |
232-242 |
NN |
denotes |
expression |
| T768 |
243-245 |
IN |
denotes |
of |
| T769 |
246-258 |
RB |
denotes |
structurally |
| T770 |
259-265 |
JJ |
denotes |
intact |
| T772 |
266-267 |
NN |
denotes |
α |
| T774 |
267-268 |
HYPH |
denotes |
- |
| T773 |
268-274 |
NN |
denotes |
globin |
| T771 |
275-280 |
NNS |
denotes |
genes |
| T775 |
280-282 |
, |
denotes |
, |
| T776 |
282-285 |
CC |
denotes |
and |
| T777 |
286-299 |
VBN |
denotes |
characterised |
| T778 |
300-302 |
IN |
denotes |
by |
| T779 |
303-306 |
DT |
denotes |
the |
| T780 |
307-315 |
NN |
denotes |
presence |
| T781 |
316-318 |
IN |
denotes |
of |
| T782 |
319-320 |
NN |
denotes |
β |
| T784 |
320-321 |
HYPH |
denotes |
- |
| T783 |
321-327 |
NN |
denotes |
globin |
| T785 |
328-337 |
NNS |
denotes |
tetramers |
| T786 |
338-339 |
-LRB- |
denotes |
( |
| T787 |
339-350 |
NN |
denotes |
haemoglobin |
| T788 |
351-352 |
NN |
denotes |
H |
| T790 |
353-362 |
NN |
denotes |
inclusion |
| T789 |
363-369 |
NNS |
denotes |
bodies |
| T791 |
369-370 |
-RRB- |
denotes |
) |
| T792 |
371-373 |
IN |
denotes |
in |
| T793 |
374-384 |
JJ |
denotes |
peripheral |
| T795 |
385-388 |
JJ |
denotes |
red |
| T796 |
389-394 |
NN |
denotes |
blood |
| T794 |
395-400 |
NNS |
denotes |
cells |
| T797 |
400-401 |
. |
denotes |
. |
| T798 |
401-521 |
sentence |
denotes |
Carrier females occasionally manifest haemoglobin H inclusions, but are otherwise intellectually and physically normal. |
| T799 |
402-409 |
NN |
denotes |
Carrier |
| T800 |
410-417 |
NNS |
denotes |
females |
| T802 |
418-430 |
RB |
denotes |
occasionally |
| T801 |
431-439 |
VBP |
denotes |
manifest |
| T803 |
440-451 |
NN |
denotes |
haemoglobin |
| T804 |
452-453 |
NN |
denotes |
H |
| T805 |
454-464 |
NNS |
denotes |
inclusions |
| T806 |
464-466 |
, |
denotes |
, |
| T807 |
466-469 |
CC |
denotes |
but |
| T808 |
470-473 |
VBP |
denotes |
are |
| T809 |
474-483 |
RB |
denotes |
otherwise |
| T810 |
484-498 |
RB |
denotes |
intellectually |
| T812 |
499-502 |
CC |
denotes |
and |
| T813 |
503-513 |
RB |
denotes |
physically |
| T811 |
514-520 |
JJ |
denotes |
normal |
| T814 |
520-521 |
. |
denotes |
. |
| T815 |
521-794 |
sentence |
denotes |
Studies of X-chromosome inactivation in carrier females have demonstrated preferential inactivation of the chromosome bearing the abnormal allele in a variety of tissues [2], and this skewing of X-inactivation is thought to explain the mild phenotype observed in carriers. |
| T816 |
522-529 |
NNS |
denotes |
Studies |
| T818 |
530-532 |
IN |
denotes |
of |
| T819 |
533-534 |
NN |
denotes |
X |
| T821 |
534-535 |
HYPH |
denotes |
- |
| T820 |
535-545 |
NN |
denotes |
chromosome |
| T822 |
546-558 |
NN |
denotes |
inactivation |
| T823 |
559-561 |
IN |
denotes |
in |
| T824 |
562-569 |
NN |
denotes |
carrier |
| T825 |
570-577 |
NNS |
denotes |
females |
| T826 |
578-582 |
VBP |
denotes |
have |
| T817 |
583-595 |
VBN |
denotes |
demonstrated |
| T827 |
596-608 |
JJ |
denotes |
preferential |
| T828 |
609-621 |
NN |
denotes |
inactivation |
| T829 |
622-624 |
IN |
denotes |
of |
| T830 |
625-628 |
DT |
denotes |
the |
| T831 |
629-639 |
NN |
denotes |
chromosome |
| T832 |
640-647 |
VBG |
denotes |
bearing |
| T833 |
648-651 |
DT |
denotes |
the |
| T835 |
652-660 |
JJ |
denotes |
abnormal |
| T834 |
661-667 |
NN |
denotes |
allele |
| T836 |
668-670 |
IN |
denotes |
in |
| T837 |
671-672 |
DT |
denotes |
a |
| T838 |
673-680 |
NN |
denotes |
variety |
| T839 |
681-683 |
IN |
denotes |
of |
| T840 |
684-691 |
NNS |
denotes |
tissues |
| T841 |
692-693 |
-LRB- |
denotes |
[ |
| T842 |
693-694 |
CD |
denotes |
2 |
| T843 |
694-695 |
-RRB- |
denotes |
] |
| T844 |
695-697 |
, |
denotes |
, |
| T845 |
697-700 |
CC |
denotes |
and |
| T846 |
701-705 |
DT |
denotes |
this |
| T847 |
706-713 |
NN |
denotes |
skewing |
| T849 |
714-716 |
IN |
denotes |
of |
| T850 |
717-718 |
NN |
denotes |
X |
| T852 |
718-719 |
HYPH |
denotes |
- |
| T851 |
719-731 |
NN |
denotes |
inactivation |
| T853 |
732-734 |
VBZ |
denotes |
is |
| T848 |
735-742 |
VBN |
denotes |
thought |
| T854 |
743-745 |
TO |
denotes |
to |
| T855 |
746-753 |
VB |
denotes |
explain |
| T856 |
754-757 |
DT |
denotes |
the |
| T858 |
758-762 |
JJ |
denotes |
mild |
| T857 |
763-772 |
NN |
denotes |
phenotype |
| T859 |
773-781 |
VBN |
denotes |
observed |
| T860 |
782-784 |
IN |
denotes |
in |
| T861 |
785-793 |
NNS |
denotes |
carriers |
| T862 |
793-794 |
. |
denotes |
. |
| R249 |
T722 |
T723 |
compound |
ATR,X |
| R250 |
T723 |
T725 |
compound |
X,syndrome |
| R251 |
T724 |
T723 |
punct |
-,X |
| R252 |
T725 |
T726 |
nsubj |
syndrome,is |
| R253 |
T727 |
T728 |
det |
a,form |
| R254 |
T728 |
T726 |
attr |
form,is |
| R255 |
T729 |
T728 |
amod |
severe,form |
| R256 |
T730 |
T728 |
punct |
", ",form |
| R257 |
T731 |
T728 |
amod |
nonprogressive,form |
| R258 |
T732 |
T728 |
prep |
of,form |
| R259 |
T733 |
T734 |
npadvmod |
X,linked |
| R260 |
T734 |
T736 |
amod |
linked,retardation |
| R261 |
T735 |
T734 |
punct |
-,linked |
| R262 |
T736 |
T732 |
pobj |
retardation,of |
| R263 |
T737 |
T736 |
amod |
mental,retardation |
| R264 |
T738 |
T739 |
dep |
that,associated |
| R265 |
T739 |
T728 |
relcl |
associated,form |
| R266 |
T740 |
T739 |
auxpass |
is,associated |
| R267 |
T741 |
T739 |
advmod |
frequently,associated |
| R268 |
T742 |
T739 |
prep |
with,associated |
| R269 |
T743 |
T744 |
amod |
multiple,abnormalities |
| R270 |
T744 |
T742 |
pobj |
abnormalities,with |
| R271 |
T745 |
T744 |
amod |
congenital,abnormalities |
| R272 |
T746 |
T747 |
punct |
[,1 |
| R273 |
T747 |
T726 |
parataxis |
1,is |
| R274 |
T748 |
T747 |
punct |
],1 |
| R275 |
T749 |
T726 |
punct |
.,is |
| R276 |
T751 |
T752 |
nsubjpass |
It,associated |
| R277 |
T753 |
T752 |
auxpass |
is,associated |
| R278 |
T754 |
T752 |
advmod |
usually,associated |
| R279 |
T755 |
T752 |
prep |
with,associated |
| R280 |
T756 |
T757 |
det |
a,form |
| R281 |
T757 |
T755 |
pobj |
form,with |
| R282 |
T758 |
T757 |
amod |
mild,form |
| R283 |
T759 |
T757 |
prep |
of,form |
| R284 |
T760 |
T761 |
compound |
α,thalassaemia |
| R285 |
T761 |
T759 |
pobj |
thalassaemia,of |
| R286 |
T762 |
T761 |
punct |
-,thalassaemia |
| R287 |
T763 |
T757 |
punct |
", ",form |
| R288 |
T764 |
T757 |
acl |
caused,form |
| R289 |
T765 |
T764 |
agent |
by,caused |
| R290 |
T766 |
T767 |
amod |
reduced,expression |
| R291 |
T767 |
T765 |
pobj |
expression,by |
| R292 |
T768 |
T767 |
prep |
of,expression |
| R293 |
T769 |
T770 |
advmod |
structurally,intact |
| R294 |
T770 |
T771 |
amod |
intact,genes |
| R295 |
T771 |
T768 |
pobj |
genes,of |
| R296 |
T772 |
T773 |
compound |
α,globin |
| R297 |
T773 |
T771 |
compound |
globin,genes |
| R298 |
T774 |
T773 |
punct |
-,globin |
| R299 |
T775 |
T752 |
punct |
", ",associated |
| R300 |
T776 |
T752 |
cc |
and,associated |
| R301 |
T777 |
T752 |
conj |
characterised,associated |
| R302 |
T778 |
T777 |
prep |
by,characterised |
| R303 |
T779 |
T780 |
det |
the,presence |
| R304 |
T780 |
T778 |
pobj |
presence,by |
| R305 |
T781 |
T780 |
prep |
of,presence |
| R306 |
T782 |
T783 |
compound |
β,globin |
| R307 |
T783 |
T785 |
compound |
globin,tetramers |
| R308 |
T784 |
T783 |
punct |
-,globin |
| R309 |
T785 |
T781 |
pobj |
tetramers,of |
| R310 |
T786 |
T785 |
punct |
(,tetramers |
| R311 |
T787 |
T788 |
compound |
haemoglobin,H |
| R312 |
T788 |
T789 |
compound |
H,bodies |
| R313 |
T789 |
T785 |
appos |
bodies,tetramers |
| R314 |
T790 |
T789 |
compound |
inclusion,bodies |
| R315 |
T791 |
T780 |
punct |
),presence |
| R316 |
T792 |
T780 |
prep |
in,presence |
| R317 |
T793 |
T794 |
amod |
peripheral,cells |
| R318 |
T794 |
T792 |
pobj |
cells,in |
| R319 |
T795 |
T794 |
amod |
red,cells |
| R320 |
T796 |
T794 |
compound |
blood,cells |
| R321 |
T797 |
T752 |
punct |
.,associated |
| R322 |
T799 |
T800 |
compound |
Carrier,females |
| R323 |
T800 |
T801 |
nsubj |
females,manifest |
| R324 |
T802 |
T801 |
advmod |
occasionally,manifest |
| R325 |
T803 |
T804 |
compound |
haemoglobin,H |
| R326 |
T804 |
T805 |
compound |
H,inclusions |
| R327 |
T805 |
T801 |
dobj |
inclusions,manifest |
| R328 |
T806 |
T801 |
punct |
", ",manifest |
| R329 |
T807 |
T801 |
cc |
but,manifest |
| R330 |
T808 |
T801 |
conj |
are,manifest |
| R331 |
T809 |
T808 |
advmod |
otherwise,are |
| R332 |
T810 |
T811 |
advmod |
intellectually,normal |
| R333 |
T811 |
T808 |
acomp |
normal,are |
| R334 |
T812 |
T810 |
cc |
and,intellectually |
| R335 |
T813 |
T810 |
conj |
physically,intellectually |
| R336 |
T814 |
T801 |
punct |
.,manifest |
| R337 |
T816 |
T817 |
nsubj |
Studies,demonstrated |
| R338 |
T818 |
T816 |
prep |
of,Studies |
| R339 |
T819 |
T820 |
compound |
X,chromosome |
| R340 |
T820 |
T822 |
compound |
chromosome,inactivation |
| R341 |
T821 |
T820 |
punct |
-,chromosome |
| R342 |
T822 |
T818 |
pobj |
inactivation,of |
| R343 |
T823 |
T822 |
prep |
in,inactivation |
| R344 |
T824 |
T825 |
compound |
carrier,females |
| R345 |
T825 |
T823 |
pobj |
females,in |
| R346 |
T826 |
T817 |
aux |
have,demonstrated |
| R347 |
T827 |
T828 |
amod |
preferential,inactivation |
| R348 |
T828 |
T817 |
dobj |
inactivation,demonstrated |
| R349 |
T829 |
T828 |
prep |
of,inactivation |
| R350 |
T830 |
T831 |
det |
the,chromosome |
| R351 |
T831 |
T829 |
pobj |
chromosome,of |
| R352 |
T832 |
T831 |
acl |
bearing,chromosome |
| R353 |
T833 |
T834 |
det |
the,allele |
| R354 |
T834 |
T832 |
dobj |
allele,bearing |
| R355 |
T835 |
T834 |
amod |
abnormal,allele |
| R356 |
T836 |
T817 |
prep |
in,demonstrated |
| R357 |
T837 |
T838 |
det |
a,variety |
| R358 |
T838 |
T836 |
pobj |
variety,in |
| R359 |
T839 |
T838 |
prep |
of,variety |
| R360 |
T840 |
T839 |
pobj |
tissues,of |
| R361 |
T841 |
T842 |
punct |
[,2 |
| R362 |
T842 |
T817 |
parataxis |
2,demonstrated |
| R363 |
T843 |
T842 |
punct |
],2 |
| R364 |
T844 |
T817 |
punct |
", ",demonstrated |
| R365 |
T845 |
T817 |
cc |
and,demonstrated |
| R366 |
T846 |
T847 |
det |
this,skewing |
| R367 |
T847 |
T848 |
nsubjpass |
skewing,thought |
| R368 |
T848 |
T817 |
conj |
thought,demonstrated |
| R369 |
T849 |
T847 |
prep |
of,skewing |
| R370 |
T850 |
T851 |
compound |
X,inactivation |
| R371 |
T851 |
T849 |
pobj |
inactivation,of |
| R372 |
T852 |
T851 |
punct |
-,inactivation |
| R373 |
T853 |
T848 |
auxpass |
is,thought |
| R374 |
T854 |
T855 |
aux |
to,explain |
| R375 |
T855 |
T848 |
xcomp |
explain,thought |
| R376 |
T856 |
T857 |
det |
the,phenotype |
| R377 |
T857 |
T855 |
dobj |
phenotype,explain |
| R378 |
T858 |
T857 |
amod |
mild,phenotype |
| R379 |
T859 |
T857 |
acl |
observed,phenotype |
| R380 |
T860 |
T859 |
prep |
in,observed |
| R381 |
T861 |
T860 |
pobj |
carriers,in |
| R382 |
T862 |
T848 |
punct |
.,thought |