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PMC:1440874 / 24397-26209 JSONTXT 5 Projects

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Id Subject Object Predicate Lexical cue
T4873 0-2 TO denotes To
T4874 3-14 VB denotes investigate
T4876 15-22 IN denotes whether
T4878 23-26 DT denotes the
T4880 27-34 VBN denotes reduced
T4879 35-39 NN denotes size
T4881 40-42 IN denotes of
T4882 43-46 DT denotes the
T4884 47-55 JJ denotes Atrxnull
T4883 56-63 NNS denotes embryos
T4877 64-67 VBD denotes was
T4885 68-71 IN denotes due
T4886 72-74 IN denotes to
T4887 75-77 DT denotes an
T4888 78-86 NN denotes increase
T4889 87-89 IN denotes in
T4890 90-99 NN denotes apoptosis
T4891 99-101 , denotes ,
T4892 101-103 PRP denotes we
T4875 104-112 VBD denotes analysed
T4893 113-121 NNS denotes sections
T4894 122-124 IN denotes of
T4895 125-133 NN denotes paraffin
T4897 133-134 HYPH denotes -
T4896 134-142 VBN denotes embedded
T4899 143-146 CD denotes 7.5
T4900 147-150 NN denotes dpc
T4898 151-158 NNS denotes embryos
T4901 159-161 IN denotes by
T4902 162-165 NN denotes TdT
T4904 165-166 HYPH denotes -
T4903 166-174 VBN denotes mediated
T4906 175-179 NN denotes dUTP
T4907 180-184 NN denotes nick
T4908 185-188 NN denotes end
T4905 189-197 NN denotes labeling
T4910 198-199 -LRB- denotes (
T4911 199-204 NN denotes TUNEL
T4912 204-205 -RRB- denotes )
T4909 206-211 NN denotes assay
T4913 212-213 -LRB- denotes (
T4915 213-219 NN denotes Figure
T4914 220-222 NN denotes 6A
T4916 222-223 -RRB- denotes )
T4917 223-224 . denotes .
T4918 224-293 sentence denotes Very few apoptotic cells were detected in wild-type 7.5 dpc embryos.
T4919 225-229 RB denotes Very
T4920 230-233 JJ denotes few
T4922 234-243 JJ denotes apoptotic
T4921 244-249 NNS denotes cells
T4924 250-254 VBD denotes were
T4923 255-263 VBN denotes detected
T4925 264-266 IN denotes in
T4926 267-271 JJ denotes wild
T4928 271-272 HYPH denotes -
T4927 272-276 NN denotes type
T4930 277-280 CD denotes 7.5
T4931 281-284 NN denotes dpc
T4929 285-292 NNS denotes embryos
T4932 292-293 . denotes .
T4933 293-373 sentence denotes In Atrxnull embryos, a slight increase in the apoptotic population was evident.
T4934 294-296 IN denotes In
T4936 297-305 JJ denotes Atrxnull
T4937 306-313 NNS denotes embryos
T4938 313-315 , denotes ,
T4939 315-316 DT denotes a
T4941 317-323 JJ denotes slight
T4940 324-332 NN denotes increase
T4942 333-335 IN denotes in
T4943 336-339 DT denotes the
T4945 340-349 JJ denotes apoptotic
T4944 350-360 NN denotes population
T4935 361-364 VBD denotes was
T4946 365-372 JJ denotes evident
T4947 372-373 . denotes .
T4948 373-628 sentence denotes However, consistent with our observation of a grossly normal apoptotic index in Atrxnull ES cells (Figure S2), the apoptotic response observed in Atrxnull embryos was also not uniform, but was restricted to a low number of scattered TUNEL-positive cells.
T4949 374-381 RB denotes However
T4951 381-383 , denotes ,
T4952 383-393 JJ denotes consistent
T4953 394-398 IN denotes with
T4954 399-402 PRP$ denotes our
T4955 403-414 NN denotes observation
T4956 415-417 IN denotes of
T4957 418-419 DT denotes a
T4959 420-427 RB denotes grossly
T4960 428-434 JJ denotes normal
T4961 435-444 JJ denotes apoptotic
T4958 445-450 NN denotes index
T4962 451-453 IN denotes in
T4963 454-462 JJ denotes Atrxnull
T4964 463-465 NN denotes ES
T4965 466-471 NNS denotes cells
T4966 472-473 -LRB- denotes (
T4968 473-479 NN denotes Figure
T4967 480-482 NN denotes S2
T4969 482-483 -RRB- denotes )
T4970 483-485 , denotes ,
T4971 485-488 DT denotes the
T4973 489-498 JJ denotes apoptotic
T4972 499-507 NN denotes response
T4974 508-516 VBN denotes observed
T4975 517-519 IN denotes in
T4976 520-528 JJ denotes Atrxnull
T4977 529-536 NNS denotes embryos
T4950 537-540 VBD denotes was
T4978 541-545 RB denotes also
T4979 546-549 RB denotes not
T4980 550-557 JJ denotes uniform
T4981 557-559 , denotes ,
T4982 559-562 CC denotes but
T4983 563-566 VBD denotes was
T4984 567-577 VBN denotes restricted
T4985 578-580 IN denotes to
T4986 581-582 DT denotes a
T4988 583-586 JJ denotes low
T4987 587-593 NN denotes number
T4989 594-596 IN denotes of
T4990 597-606 VBN denotes scattered
T4992 607-612 NN denotes TUNEL
T4994 612-613 HYPH denotes -
T4993 613-621 JJ denotes positive
T4991 622-627 NNS denotes cells
T4995 627-628 . denotes .
T4996 628-929 sentence denotes Since this small apoptotic response is unlikely to account fully for the dramatic size deficit observed in Atrxnull embryos, a possible proliferation defect was also investigated by immunohistochemical staining of 7.5 dpc embryo sections for the mitosis marker phosphorylated (Ser10) histone H3 [13].
T4997 629-634 IN denotes Since
T4999 635-639 DT denotes this
T5001 640-645 JJ denotes small
T5002 646-655 JJ denotes apoptotic
T5000 656-664 NN denotes response
T4998 665-667 VBZ denotes is
T5004 668-676 JJ denotes unlikely
T5005 677-679 TO denotes to
T5006 680-687 VB denotes account
T5007 688-693 RB denotes fully
T5008 694-697 IN denotes for
T5009 698-701 DT denotes the
T5011 702-710 JJ denotes dramatic
T5012 711-715 NN denotes size
T5010 716-723 NN denotes deficit
T5013 724-732 VBN denotes observed
T5014 733-735 IN denotes in
T5015 736-744 JJ denotes Atrxnull
T5016 745-752 NNS denotes embryos
T5017 752-754 , denotes ,
T5018 754-755 DT denotes a
T5020 756-764 JJ denotes possible
T5021 765-778 NN denotes proliferation
T5019 779-785 NN denotes defect
T5022 786-789 VBD denotes was
T5023 790-794 RB denotes also
T5003 795-807 VBN denotes investigated
T5024 808-810 IN denotes by
T5025 811-830 JJ denotes immunohistochemical
T5026 831-839 NN denotes staining
T5027 840-842 IN denotes of
T5028 843-846 CD denotes 7.5
T5029 847-850 NN denotes dpc
T5030 851-857 NN denotes embryo
T5031 858-866 NNS denotes sections
T5032 867-870 IN denotes for
T5033 871-874 DT denotes the
T5035 875-882 NN denotes mitosis
T5036 883-889 NN denotes marker
T5037 890-904 VBN denotes phosphorylated
T5038 905-906 -LRB- denotes (
T5039 906-911 NN denotes Ser10
T5040 911-912 -RRB- denotes )
T5041 913-920 NN denotes histone
T5034 921-923 NN denotes H3
T5042 924-925 -LRB- denotes [
T5043 925-927 CD denotes 13
T5044 927-928 -RRB- denotes ]
T5045 928-929 . denotes .
T5046 929-1110 sentence denotes Relative to the very high mitotic index observed in wild-type embryos, the proportion of mitotic cells observed in Atrxnull embryos at 7.5 dpc was dramatically reduced (Figure 6B).
T5047 930-938 JJ denotes Relative
T5049 939-941 IN denotes to
T5050 942-945 DT denotes the
T5052 946-950 RB denotes very
T5053 951-955 JJ denotes high
T5054 956-963 JJ denotes mitotic
T5051 964-969 NN denotes index
T5055 970-978 VBN denotes observed
T5056 979-981 IN denotes in
T5057 982-986 JJ denotes wild
T5059 986-987 HYPH denotes -
T5058 987-991 NN denotes type
T5060 992-999 NNS denotes embryos
T5061 999-1001 , denotes ,
T5062 1001-1004 DT denotes the
T5063 1005-1015 NN denotes proportion
T5064 1016-1018 IN denotes of
T5065 1019-1026 JJ denotes mitotic
T5066 1027-1032 NNS denotes cells
T5067 1033-1041 VBN denotes observed
T5068 1042-1044 IN denotes in
T5069 1045-1053 JJ denotes Atrxnull
T5070 1054-1061 NNS denotes embryos
T5071 1062-1064 IN denotes at
T5072 1065-1068 CD denotes 7.5
T5073 1069-1072 NN denotes dpc
T5074 1073-1076 VBD denotes was
T5075 1077-1089 RB denotes dramatically
T5048 1090-1097 VBN denotes reduced
T5076 1098-1099 -LRB- denotes (
T5078 1099-1105 NN denotes Figure
T5077 1106-1108 NN denotes 6B
T5079 1108-1109 -RRB- denotes )
T5080 1109-1110 . denotes .
T5081 1110-1324 sentence denotes Taken together, these results suggest that the size deficit observed in Atrxnull embryos prior to lethality largely reflects a proliferative defect, with a minor but indirect contribution from increased apoptosis.
T5082 1111-1116 VBN denotes Taken
T5084 1117-1125 RB denotes together
T5085 1125-1127 , denotes ,
T5086 1127-1132 DT denotes these
T5087 1133-1140 NNS denotes results
T5083 1141-1148 VBP denotes suggest
T5088 1149-1153 IN denotes that
T5090 1154-1157 DT denotes the
T5092 1158-1162 NN denotes size
T5091 1163-1170 NN denotes deficit
T5093 1171-1179 VBN denotes observed
T5094 1180-1182 IN denotes in
T5095 1183-1191 JJ denotes Atrxnull
T5096 1192-1199 NNS denotes embryos
T5097 1200-1205 JJ denotes prior
T5098 1206-1208 IN denotes to
T5099 1209-1218 NN denotes lethality
T5100 1219-1226 RB denotes largely
T5089 1227-1235 VBZ denotes reflects
T5101 1236-1237 DT denotes a
T5103 1238-1251 JJ denotes proliferative
T5102 1252-1258 NN denotes defect
T5104 1258-1260 , denotes ,
T5105 1260-1264 IN denotes with
T5106 1265-1266 DT denotes a
T5108 1267-1272 JJ denotes minor
T5109 1273-1276 CC denotes but
T5110 1277-1285 JJ denotes indirect
T5107 1286-1298 NN denotes contribution
T5111 1299-1303 IN denotes from
T5112 1304-1313 VBN denotes increased
T5113 1314-1323 NN denotes apoptosis
T5114 1323-1324 . denotes .
T5115 1324-1550 sentence denotes Although a growth defect was also observed in Atrxnull ES cells (Figure 3A), in contrast to the Atrxnull embryos, the mitotic index of the ES cell population (as measured with the same antibody) was not depleted (Figure S1B).
T5116 1325-1333 IN denotes Although
T5118 1334-1335 DT denotes a
T5120 1336-1342 NN denotes growth
T5119 1343-1349 NN denotes defect
T5121 1350-1353 VBD denotes was
T5122 1354-1358 RB denotes also
T5117 1359-1367 VBN denotes observed
T5124 1368-1370 IN denotes in
T5125 1371-1379 JJ denotes Atrxnull
T5127 1380-1382 NN denotes ES
T5126 1383-1388 NNS denotes cells
T5128 1389-1390 -LRB- denotes (
T5130 1390-1396 NN denotes Figure
T5129 1397-1399 NN denotes 3A
T5131 1399-1400 -RRB- denotes )
T5132 1400-1402 , denotes ,
T5133 1402-1404 IN denotes in
T5134 1405-1413 NN denotes contrast
T5135 1414-1416 IN denotes to
T5136 1417-1420 DT denotes the
T5138 1421-1429 JJ denotes Atrxnull
T5137 1430-1437 NNS denotes embryos
T5139 1437-1439 , denotes ,
T5140 1439-1442 DT denotes the
T5142 1443-1450 JJ denotes mitotic
T5141 1451-1456 NN denotes index
T5143 1457-1459 IN denotes of
T5144 1460-1463 DT denotes the
T5146 1464-1466 NN denotes ES
T5147 1467-1471 NN denotes cell
T5145 1472-1482 NN denotes population
T5148 1483-1484 -LRB- denotes (
T5149 1484-1486 IN denotes as
T5150 1487-1495 VBN denotes measured
T5151 1496-1500 IN denotes with
T5152 1501-1504 DT denotes the
T5154 1505-1509 JJ denotes same
T5153 1510-1518 NN denotes antibody
T5155 1518-1519 -RRB- denotes )
T5156 1520-1523 VBD denotes was
T5157 1524-1527 RB denotes not
T5123 1528-1536 VBN denotes depleted
T5158 1537-1538 -LRB- denotes (
T5160 1538-1544 NN denotes Figure
T5159 1545-1548 NN denotes S1B
T5161 1548-1549 -RRB- denotes )
T5162 1549-1550 . denotes .
T5163 1550-1812 sentence denotes These observations suggest that the mitotic defect observed in embryos is unlikely to be a direct, cell-autonomous effect of the absence of Atrx, and is more likely to be a secondary effect resulting from the failure to develop a normal trophoblast (see below).
T5164 1551-1556 DT denotes These
T5165 1557-1569 NNS denotes observations
T5166 1570-1577 VBP denotes suggest
T5167 1578-1582 IN denotes that
T5169 1583-1586 DT denotes the
T5171 1587-1594 JJ denotes mitotic
T5170 1595-1601 NN denotes defect
T5172 1602-1610 VBN denotes observed
T5173 1611-1613 IN denotes in
T5174 1614-1621 NNS denotes embryos
T5168 1622-1624 VBZ denotes is
T5175 1625-1633 JJ denotes unlikely
T5176 1634-1636 TO denotes to
T5177 1637-1639 VB denotes be
T5178 1640-1641 DT denotes a
T5180 1642-1648 JJ denotes direct
T5181 1648-1650 , denotes ,
T5182 1650-1654 NN denotes cell
T5184 1654-1655 HYPH denotes -
T5183 1655-1665 JJ denotes autonomous
T5179 1666-1672 NN denotes effect
T5185 1673-1675 IN denotes of
T5186 1676-1679 DT denotes the
T5187 1680-1687 NN denotes absence
T5188 1688-1690 IN denotes of
T5189 1691-1695 NN denotes Atrx
T5190 1695-1697 , denotes ,
T5191 1697-1700 CC denotes and
T5192 1701-1703 VBZ denotes is
T5193 1704-1708 RBR denotes more
T5194 1709-1715 JJ denotes likely
T5195 1716-1718 TO denotes to
T5196 1719-1721 VB denotes be
T5197 1722-1723 DT denotes a
T5199 1724-1733 JJ denotes secondary
T5198 1734-1740 NN denotes effect
T5200 1741-1750 VBG denotes resulting
T5201 1751-1755 IN denotes from
T5202 1756-1759 DT denotes the
T5203 1760-1767 NN denotes failure
T5204 1768-1770 TO denotes to
T5205 1771-1778 VB denotes develop
T5206 1779-1780 DT denotes a
T5208 1781-1787 JJ denotes normal
T5207 1788-1799 NN denotes trophoblast
T5209 1800-1801 -LRB- denotes (
T5210 1801-1804 VB denotes see
T5211 1805-1810 RB denotes below
T5212 1810-1811 -RRB- denotes )
T5213 1811-1812 . denotes .
R2960 T4873 T4874 aux To,investigate
R2961 T4874 T4875 advcl investigate,analysed
R2962 T4876 T4877 mark whether,was
R2963 T4877 T4874 ccomp was,investigate
R2964 T4878 T4879 det the,size
R2965 T4879 T4877 nsubj size,was
R2966 T4880 T4879 amod reduced,size
R2967 T4881 T4879 prep of,size
R2968 T4882 T4883 det the,embryos
R2969 T4883 T4881 pobj embryos,of
R2970 T4884 T4883 amod Atrxnull,embryos
R2971 T4885 T4877 prep due,was
R2972 T4886 T4885 pcomp to,due
R2973 T4887 T4888 det an,increase
R2974 T4888 T4885 pobj increase,due
R2975 T4889 T4888 prep in,increase
R2976 T4890 T4889 pobj apoptosis,in
R2977 T4891 T4875 punct ", ",analysed
R2978 T4892 T4875 nsubj we,analysed
R2979 T4893 T4875 dobj sections,analysed
R2980 T4894 T4893 prep of,sections
R2981 T4895 T4896 npadvmod paraffin,embedded
R2982 T4896 T4898 amod embedded,embryos
R2983 T4897 T4896 punct -,embedded
R2984 T4898 T4894 pobj embryos,of
R2985 T4899 T4900 nummod 7.5,dpc
R2986 T4900 T4898 compound dpc,embryos
R2987 T4901 T4875 prep by,analysed
R2988 T4902 T4903 npadvmod TdT,mediated
R2989 T4903 T4905 amod mediated,labeling
R2990 T4904 T4903 punct -,mediated
R2991 T4905 T4909 nmod labeling,assay
R2992 T4906 T4905 nmod dUTP,labeling
R2993 T4907 T4905 nmod nick,labeling
R2994 T5014 T5013 prep in,observed
R2995 T5015 T5016 amod Atrxnull,embryos
R2996 T5016 T5014 pobj embryos,in
R2997 T5017 T5003 punct ", ",investigated
R2998 T5018 T5019 det a,defect
R2999 T5019 T5003 nsubjpass defect,investigated
R3000 T5020 T5019 amod possible,defect
R3001 T5021 T5019 compound proliferation,defect
R3002 T5022 T5003 auxpass was,investigated
R3003 T5023 T5003 advmod also,investigated
R3004 T5024 T5003 prep by,investigated
R3005 T5025 T5026 amod immunohistochemical,staining
R3006 T5026 T5024 pobj staining,by
R3007 T5027 T5026 prep of,staining
R3008 T5028 T5029 nummod 7.5,dpc
R3009 T5029 T5030 compound dpc,embryo
R3010 T5030 T5031 compound embryo,sections
R3011 T5031 T5027 pobj sections,of
R3012 T5032 T5003 prep for,investigated
R3013 T5033 T5034 det the,H3
R3014 T5034 T5032 pobj H3,for
R3015 T5035 T5036 compound mitosis,marker
R3016 T4908 T4905 nmod end,labeling
R3017 T5036 T5037 npadvmod marker,phosphorylated
R3018 T4909 T4901 pobj assay,by
R3019 T4910 T4905 punct (,labeling
R3020 T5037 T5034 amod phosphorylated,H3
R3021 T4911 T4905 appos TUNEL,labeling
R3022 T4912 T4909 punct ),assay
R3023 T5038 T5039 punct (,Ser10
R3024 T4913 T4914 punct (,6A
R3025 T4914 T4875 parataxis 6A,analysed
R3026 T4915 T4914 compound Figure,6A
R3027 T5039 T5037 parataxis Ser10,phosphorylated
R3028 T4916 T4914 punct ),6A
R3029 T4917 T4875 punct .,analysed
R3030 T4919 T4920 advmod Very,few
R3031 T4920 T4921 amod few,cells
R3032 T5040 T5039 punct ),Ser10
R3033 T4921 T4923 nsubjpass cells,detected
R3034 T4922 T4921 amod apoptotic,cells
R3035 T5041 T5034 compound histone,H3
R3036 T4924 T4923 auxpass were,detected
R3037 T4925 T4923 prep in,detected
R3038 T5042 T5043 punct [,13
R3039 T4926 T4927 amod wild,type
R3040 T4927 T4929 nmod type,embryos
R3041 T4928 T4927 punct -,type
R3042 T5043 T5003 parataxis 13,investigated
R3043 T4929 T4925 pobj embryos,in
R3044 T4930 T4931 nummod 7.5,dpc
R3045 T4931 T4929 compound dpc,embryos
R3046 T5044 T5043 punct ],13
R3047 T4932 T4923 punct .,detected
R3048 T5045 T5003 punct .,investigated
R3049 T4934 T4935 prep In,was
R3050 T4936 T4937 amod Atrxnull,embryos
R3051 T5047 T5048 advcl Relative,reduced
R3052 T4937 T4934 pobj embryos,In
R3053 T4938 T4935 punct ", ",was
R3054 T4939 T4940 det a,increase
R3055 T5049 T5047 prep to,Relative
R3056 T4940 T4935 nsubj increase,was
R3057 T4941 T4940 amod slight,increase
R3058 T4942 T4940 prep in,increase
R3059 T4943 T4944 det the,population
R3060 T4944 T4942 pobj population,in
R3061 T5050 T5051 det the,index
R3062 T4945 T4944 amod apoptotic,population
R3063 T4946 T4935 acomp evident,was
R3064 T4947 T4935 punct .,was
R3065 T5051 T5049 pobj index,to
R3066 T4949 T4950 advmod However,was
R3067 T4951 T4950 punct ", ",was
R3068 T5052 T5053 advmod very,high
R3069 T4952 T4950 advcl consistent,was
R3070 T4953 T4952 prep with,consistent
R3071 T4954 T4955 poss our,observation
R3072 T5053 T5051 amod high,index
R3073 T4955 T4953 pobj observation,with
R3074 T4956 T4955 prep of,observation
R3075 T4957 T4958 det a,index
R3076 T5054 T5051 amod mitotic,index
R3077 T4958 T4956 pobj index,of
R3078 T4959 T4960 advmod grossly,normal
R3079 T4960 T4958 amod normal,index
R3080 T5055 T5051 acl observed,index
R3081 T4961 T4958 amod apoptotic,index
R3082 T4962 T4955 prep in,observation
R3083 T4963 T4964 amod Atrxnull,ES
R3084 T4964 T4965 compound ES,cells
R3085 T4965 T4962 pobj cells,in
R3086 T5056 T5055 prep in,observed
R3087 T4966 T4967 punct (,S2
R3088 T5057 T5058 amod wild,type
R3089 T4967 T4952 parataxis S2,consistent
R3090 T5058 T5060 compound type,embryos
R3091 T4968 T4967 compound Figure,S2
R3092 T4969 T4967 punct ),S2
R3093 T4970 T4950 punct ", ",was
R3094 T5059 T5058 punct -,type
R3095 T4971 T4972 det the,response
R3096 T4972 T4950 nsubj response,was
R3097 T5060 T5056 pobj embryos,in
R3098 T4973 T4972 amod apoptotic,response
R3099 T4974 T4972 acl observed,response
R3100 T4975 T4974 prep in,observed
R3101 T5061 T5048 punct ", ",reduced
R3102 T4976 T4977 amod Atrxnull,embryos
R3103 T4977 T4975 pobj embryos,in
R3104 T5062 T5063 det the,proportion
R3105 T4978 T4950 advmod also,was
R3106 T4979 T4950 neg not,was
R3107 T4980 T4950 acomp uniform,was
R3108 T5063 T5048 nsubjpass proportion,reduced
R3109 T4981 T4950 punct ", ",was
R3110 T4982 T4950 cc but,was
R3111 T5064 T5063 prep of,proportion
R3112 T4983 T4984 auxpass was,restricted
R3113 T4984 T4950 conj restricted,was
R3114 T4985 T4984 prep to,restricted
R3115 T5065 T5066 amod mitotic,cells
R3116 T4986 T4987 det a,number
R3117 T4987 T4985 pobj number,to
R3118 T4988 T4987 amod low,number
R3119 T5066 T5064 pobj cells,of
R3120 T4989 T4987 prep of,number
R3121 T4990 T4991 amod scattered,cells
R3122 T4991 T4989 pobj cells,of
R3123 T5067 T5066 acl observed,cells
R3124 T4992 T4993 npadvmod TUNEL,positive
R3125 T4993 T4991 amod positive,cells
R3126 T4994 T4993 punct -,positive
R3127 T5068 T5067 prep in,observed
R3128 T4995 T4950 punct .,was
R3129 T5069 T5070 amod Atrxnull,embryos
R3130 T4997 T4998 mark Since,is
R3131 T4998 T5003 advcl is,investigated
R3132 T4999 T5000 det this,response
R3133 T5070 T5068 pobj embryos,in
R3134 T5000 T4998 nsubj response,is
R3135 T5001 T5000 amod small,response
R3136 T5002 T5000 amod apoptotic,response
R3137 T5004 T4998 acomp unlikely,is
R3138 T5005 T5006 aux to,account
R3139 T5071 T5067 prep at,observed
R3140 T5006 T5004 xcomp account,unlikely
R3141 T5007 T5006 advmod fully,account
R3142 T5008 T5006 prep for,account
R3143 T5072 T5073 nummod 7.5,dpc
R3144 T5009 T5010 det the,deficit
R3145 T5010 T5008 pobj deficit,for
R3146 T5073 T5071 pobj dpc,at
R3147 T5011 T5010 amod dramatic,deficit
R3148 T5012 T5010 compound size,deficit
R3149 T5013 T5010 acl observed,deficit
R3150 T5074 T5048 auxpass was,reduced
R3151 T5075 T5048 advmod dramatically,reduced
R3152 T5076 T5077 punct (,6B
R3153 T5077 T5048 parataxis 6B,reduced
R3154 T5078 T5077 compound Figure,6B
R3155 T5079 T5077 punct ),6B
R3156 T5080 T5048 punct .,reduced
R3157 T5120 T5119 compound growth,defect
R3158 T5082 T5083 advcl Taken,suggest
R3159 T5121 T5117 auxpass was,observed
R3160 T5122 T5117 advmod also,observed
R3161 T5084 T5082 advmod together,Taken
R3162 T5124 T5117 prep in,observed
R3163 T5125 T5126 amod Atrxnull,cells
R3164 T5126 T5124 pobj cells,in
R3165 T5085 T5083 punct ", ",suggest
R3166 T5127 T5126 compound ES,cells
R3167 T5128 T5129 punct (,3A
R3168 T5129 T5117 parataxis 3A,observed
R3169 T5086 T5087 det these,results
R3170 T5130 T5129 compound Figure,3A
R3171 T5131 T5129 punct ),3A
R3172 T5087 T5083 nsubj results,suggest
R3173 T5132 T5123 punct ", ",depleted
R3174 T5133 T5123 prep in,depleted
R3175 T5134 T5133 pobj contrast,in
R3176 T5088 T5089 mark that,reflects
R3177 T5135 T5134 prep to,contrast
R3178 T5136 T5137 det the,embryos
R3179 T5089 T5083 ccomp reflects,suggest
R3180 T5090 T5091 det the,deficit
R3181 T5137 T5135 pobj embryos,to
R3182 T5091 T5089 nsubj deficit,reflects
R3183 T5138 T5137 amod Atrxnull,embryos
R3184 T5139 T5123 punct ", ",depleted
R3185 T5140 T5141 det the,index
R3186 T5141 T5123 nsubjpass index,depleted
R3187 T5092 T5091 compound size,deficit
R3188 T5142 T5141 amod mitotic,index
R3189 T5143 T5141 prep of,index
R3190 T5144 T5145 det the,population
R3191 T5093 T5091 acl observed,deficit
R3192 T5145 T5143 pobj population,of
R3193 T5146 T5147 compound ES,cell
R3194 T5094 T5093 prep in,observed
R3195 T5147 T5145 compound cell,population
R3196 T5148 T5141 punct (,index
R3197 T5095 T5096 amod Atrxnull,embryos
R3198 T5149 T5150 mark as,measured
R3199 T5150 T5141 advcl measured,index
R3200 T5151 T5150 prep with,measured
R3201 T5096 T5094 pobj embryos,in
R3202 T5152 T5153 det the,antibody
R3203 T5153 T5151 pobj antibody,with
R3204 T5097 T5098 amod prior,to
R3205 T5154 T5153 amod same,antibody
R3206 T5155 T5123 punct ),depleted
R3207 T5156 T5123 auxpass was,depleted
R3208 T5098 T5093 prep to,observed
R3209 T5157 T5123 neg not,depleted
R3210 T5158 T5159 punct (,S1B
R3211 T5099 T5098 pobj lethality,to
R3212 T5159 T5123 parataxis S1B,depleted
R3213 T5160 T5159 compound Figure,S1B
R3214 T5161 T5159 punct ),S1B
R3215 T5100 T5089 advmod largely,reflects
R3216 T5162 T5123 punct .,depleted
R3217 T5101 T5102 det a,defect
R3218 T5164 T5165 det These,observations
R3219 T5165 T5166 nsubj observations,suggest
R3220 T5167 T5168 mark that,is
R3221 T5102 T5089 dobj defect,reflects
R3222 T5168 T5166 ccomp is,suggest
R3223 T5169 T5170 det the,defect
R3224 T5170 T5168 nsubj defect,is
R3225 T5103 T5102 amod proliferative,defect
R3226 T5171 T5170 amod mitotic,defect
R3227 T5172 T5170 acl observed,defect
R3228 T5104 T5089 punct ", ",reflects
R3229 T5173 T5172 prep in,observed
R3230 T5174 T5173 pobj embryos,in
R3231 T5175 T5168 acomp unlikely,is
R3232 T5105 T5089 prep with,reflects
R3233 T5176 T5177 aux to,be
R3234 T5177 T5175 xcomp be,unlikely
R3235 T5106 T5107 det a,contribution
R3236 T5178 T5179 det a,effect
R3237 T5179 T5177 attr effect,be
R3238 T5180 T5179 amod direct,effect
R3239 T5181 T5179 punct ", ",effect
R3240 T5182 T5183 npadvmod cell,autonomous
R3241 T5107 T5105 pobj contribution,with
R3242 T5183 T5179 amod autonomous,effect
R3243 T5184 T5183 punct -,autonomous
R3244 T5185 T5179 prep of,effect
R3245 T5186 T5187 det the,absence
R3246 T5108 T5107 amod minor,contribution
R3247 T5187 T5185 pobj absence,of
R3248 T5188 T5187 prep of,absence
R3249 T5109 T5108 cc but,minor
R3250 T5189 T5188 pobj Atrx,of
R3251 T5190 T5168 punct ", ",is
R3252 T5110 T5108 conj indirect,minor
R3253 T5191 T5168 cc and,is
R3254 T5192 T5168 conj is,is
R3255 T5193 T5194 advmod more,likely
R3256 T5111 T5107 prep from,contribution
R3257 T5194 T5192 acomp likely,is
R3258 T5112 T5113 amod increased,apoptosis
R3259 T5195 T5196 aux to,be
R3260 T5113 T5111 pobj apoptosis,from
R3261 T5196 T5194 xcomp be,likely
R3262 T5197 T5198 det a,effect
R3263 T5198 T5196 attr effect,be
R3264 T5114 T5083 punct .,suggest
R3265 T5199 T5198 amod secondary,effect
R3266 T5200 T5198 acl resulting,effect
R3267 T5116 T5117 mark Although,observed
R3268 T5201 T5200 prep from,resulting
R3269 T5202 T5203 det the,failure
R3270 T5203 T5201 pobj failure,from
R3271 T5117 T5123 advcl observed,depleted
R3272 T5204 T5205 aux to,develop
R3273 T5205 T5203 acl develop,failure
R3274 T5206 T5207 det a,trophoblast
R3275 T5118 T5119 det a,defect
R3276 T5207 T5205 dobj trophoblast,develop
R3277 T5208 T5207 amod normal,trophoblast
R3278 T5209 T5210 punct (,see
R3279 T5119 T5117 nsubjpass defect,observed
R3280 T5210 T5194 parataxis see,likely
R3281 T5211 T5210 advmod below,see
R3282 T5212 T5210 punct ),see
R3283 T5213 T5166 punct .,suggest