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PMC:1420314 / 3800-4540 JSONTXT 4 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function

Id Subject Object Predicate Lexical cue
T2689 0-6 NN denotes ADAM11
T2690 7-9 VBZ denotes is
T2691 10-13 DT denotes the
T2693 14-21 JJS denotes closest
T2692 22-29 NN denotes paralog
T2694 30-32 IN denotes of
T2695 33-39 NN denotes ADAM22
T2696 40-43 CC denotes and
T2697 44-50 NN denotes ADAM23
T2698 50-52 , denotes ,
T2699 52-55 CC denotes and
T2700 56-59 PRP$ denotes its
T2701 60-69 NNS denotes orthologs
T2703 70-74 VBP denotes have
T2704 75-79 VBN denotes been
T2702 80-85 VBN denotes found
T2705 86-88 IN denotes in
T2706 89-100 NNS denotes vertebrates
T2707 100-102 , denotes ,
T2708 102-105 CC denotes but
T2709 106-109 RB denotes not
T2710 110-112 IN denotes in
T2711 113-126 NNS denotes invertebrates
T2712 126-127 . denotes .
T2713 127-487 sentence denotes It has been reported that the Xenopus ADAM11 ortholog, xMDC11a, has an expression pattern associated with neural development, with a proposed role in cell migration [24]; and it has been reported in analyses using Northern blot and in situ hybridisation methods that the murine Adam11 gene is expressed in both the developing and adult nervous system [19,25].
T2714 128-130 PRP denotes It
T2716 131-134 VBZ denotes has
T2717 135-139 VBN denotes been
T2715 140-148 VBN denotes reported
T2718 149-153 IN denotes that
T2720 154-157 DT denotes the
T2722 158-165 NNP denotes Xenopus
T2723 166-172 NN denotes ADAM11
T2721 173-181 NN denotes ortholog
T2724 181-183 , denotes ,
T2725 183-190 NN denotes xMDC11a
T2726 190-192 , denotes ,
T2719 192-195 VBZ denotes has
T2727 196-198 DT denotes an
T2729 199-209 NN denotes expression
T2728 210-217 NN denotes pattern
T2730 218-228 VBN denotes associated
T2731 229-233 IN denotes with
T2732 234-240 JJ denotes neural
T2733 241-252 NN denotes development
T2734 252-254 , denotes ,
T2735 254-258 IN denotes with
T2736 259-260 DT denotes a
T2738 261-269 VBN denotes proposed
T2737 270-274 NN denotes role
T2739 275-277 IN denotes in
T2740 278-282 NN denotes cell
T2741 283-292 NN denotes migration
T2742 293-294 -LRB- denotes [
T2743 294-296 CD denotes 24
T2744 296-297 -RRB- denotes ]
T2745 297-298 : denotes ;
T2746 299-302 CC denotes and
T2747 303-305 PRP denotes it
T2749 306-309 VBZ denotes has
T2750 310-314 VBN denotes been
T2748 315-323 VBN denotes reported
T2751 324-326 IN denotes in
T2752 327-335 NNS denotes analyses
T2753 336-341 VBG denotes using
T2754 342-350 NNP denotes Northern
T2755 351-355 NN denotes blot
T2757 356-359 CC denotes and
T2758 360-362 FW denotes in
T2759 363-367 FW denotes situ
T2760 368-381 NN denotes hybridisation
T2756 382-389 NNS denotes methods
T2761 390-394 IN denotes that
T2763 395-398 DT denotes the
T2765 399-405 JJ denotes murine
T2766 406-412 NN denotes Adam11
T2764 413-417 NN denotes gene
T2767 418-420 VBZ denotes is
T2762 421-430 VBN denotes expressed
T2768 431-433 IN denotes in
T2769 434-438 CC denotes both
T2771 439-442 DT denotes the
T2772 443-453 VBG denotes developing
T2773 454-457 CC denotes and
T2774 458-463 JJ denotes adult
T2775 464-471 JJ denotes nervous
T2770 472-478 NN denotes system
T2776 479-480 -LRB- denotes [
T2778 480-482 CD denotes 19
T2779 482-483 , denotes ,
T2777 483-485 CD denotes 25
T2780 485-486 -RRB- denotes ]
T2781 486-487 . denotes .
T2782 487-635 sentence denotes These findings led us to hypothesise that ADAM11 is an integrin binder that plays an important role in the nervous system, as do ADAM22 and ADAM23.
T2783 488-493 DT denotes These
T2784 494-502 NNS denotes findings
T2785 503-506 VBD denotes led
T2786 507-509 PRP denotes us
T2787 510-512 TO denotes to
T2788 513-524 VB denotes hypothesise
T2789 525-529 IN denotes that
T2791 530-536 NN denotes ADAM11
T2790 537-539 VBZ denotes is
T2792 540-542 DT denotes an
T2794 543-551 NN denotes integrin
T2793 552-558 NN denotes binder
T2795 559-563 WDT denotes that
T2796 564-569 VBZ denotes plays
T2797 570-572 DT denotes an
T2799 573-582 JJ denotes important
T2798 583-587 NN denotes role
T2800 588-590 IN denotes in
T2801 591-594 DT denotes the
T2803 595-602 JJ denotes nervous
T2802 603-609 NN denotes system
T2804 609-611 , denotes ,
T2805 611-613 IN denotes as
T2806 614-616 VBP denotes do
T2807 617-623 NN denotes ADAM22
T2808 624-627 CC denotes and
T2809 628-634 NN denotes ADAM23
T2810 634-635 . denotes .
T2811 635-740 sentence denotes To determine the physiological functions of ADAM11, we generated and analysed Adam11 gene-targeted mice.
T2812 636-638 TO denotes To
T2813 639-648 VB denotes determine
T2815 649-652 DT denotes the
T2817 653-666 JJ denotes physiological
T2816 667-676 NNS denotes functions
T2818 677-679 IN denotes of
T2819 680-686 NN denotes ADAM11
T2820 686-688 , denotes ,
T2821 688-690 PRP denotes we
T2814 691-700 VBD denotes generated
T2822 701-704 CC denotes and
T2823 705-713 VBD denotes analysed
T2824 714-720 NN denotes Adam11
T2826 721-725 NN denotes gene
T2828 725-726 HYPH denotes -
T2827 726-734 VBN denotes targeted
T2825 735-739 NNS denotes mice
T2829 739-740 . denotes .
R663 T2742 T2743 punct [,24
R664 T2743 T2715 parataxis 24,reported
R666 T2744 T2743 punct ],24
R667 T2745 T2715 punct ;,reported
R669 T2746 T2715 cc and,reported
R670 T2747 T2748 nsubjpass it,reported
R671 T2748 T2715 conj reported,reported
R672 T2749 T2748 aux has,reported
R674 T2750 T2748 auxpass been,reported
R675 T2751 T2748 prep in,reported
R677 T2752 T2751 pobj analyses,in
R678 T2753 T2752 acl using,analyses
R679 T2689 T2690 nsubj ADAM11,is
R680 T2754 T2755 nmod Northern,blot
R681 T2755 T2756 nmod blot,methods
R682 T2756 T2753 dobj methods,using
R683 T2757 T2755 cc and,blot
R684 T2691 T2692 det the,paralog
R685 T2758 T2759 advmod in,situ
R686 T2759 T2755 conj situ,blot
R687 T2760 T2756 compound hybridisation,methods
R688 T2761 T2762 mark that,expressed
R689 T2692 T2690 attr paralog,is
R690 T2762 T2748 ccomp expressed,reported
R691 T2763 T2764 det the,gene
R692 T2764 T2762 nsubjpass gene,expressed
R693 T2765 T2764 amod murine,gene
R694 T2766 T2764 compound Adam11,gene
R695 T2767 T2762 auxpass is,expressed
R696 T2693 T2692 amod closest,paralog
R697 T2768 T2762 prep in,expressed
R698 T2769 T2770 preconj both,system
R699 T2770 T2768 pobj system,in
R700 T2694 T2692 prep of,paralog
R701 T2771 T2770 det the,system
R702 T2772 T2770 amod developing,system
R703 T2773 T2772 cc and,developing
R704 T2695 T2694 pobj ADAM22,of
R705 T2774 T2772 conj adult,developing
R706 T2775 T2770 amod nervous,system
R707 T2696 T2695 cc and,ADAM22
R708 T2776 T2777 punct [,25
R709 T2777 T2748 parataxis 25,reported
R710 T2778 T2777 nummod 19,25
R711 T2697 T2695 conj ADAM23,ADAM22
R712 T2779 T2777 punct ",",25
R713 T2780 T2777 punct ],25
R714 T2781 T2748 punct .,reported
R715 T2698 T2690 punct ", ",is
R716 T2783 T2784 det These,findings
R717 T2784 T2785 nsubj findings,led
R718 T2699 T2690 cc and,is
R719 T2786 T2785 dobj us,led
R720 T2700 T2701 poss its,orthologs
R721 T2787 T2788 aux to,hypothesise
R722 T2788 T2785 xcomp hypothesise,led
R723 T2789 T2790 mark that,is
R724 T2790 T2788 ccomp is,hypothesise
R725 T2701 T2702 nsubjpass orthologs,found
R726 T2791 T2790 nsubj ADAM11,is
R727 T2792 T2793 det an,binder
R728 T2702 T2690 conj found,is
R729 T2703 T2702 aux have,found
R730 T2704 T2702 auxpass been,found
R731 T2793 T2790 attr binder,is
R732 T2705 T2702 prep in,found
R733 T2794 T2793 compound integrin,binder
R734 T2795 T2796 dep that,plays
R735 T2796 T2793 relcl plays,binder
R736 T2797 T2798 det an,role
R737 T2706 T2705 pobj vertebrates,in
R738 T2798 T2796 dobj role,plays
R739 T2799 T2798 amod important,role
R740 T2800 T2796 prep in,plays
R741 T2707 T2705 punct ", ",in
R742 T2801 T2802 det the,system
R743 T2708 T2705 cc but,in
R744 T2802 T2800 pobj system,in
R745 T2803 T2802 amod nervous,system
R746 T2804 T2796 punct ", ",plays
R747 T2805 T2806 mark as,do
R748 T2806 T2796 advcl do,plays
R749 T2807 T2806 nsubj ADAM22,do
R750 T2709 T2708 neg not,but
R751 T2808 T2807 cc and,ADAM22
R752 T2809 T2807 conj ADAM23,ADAM22
R753 T2810 T2785 punct .,led
R754 T2710 T2705 conj in,in
R755 T2812 T2813 aux To,determine
R756 T2813 T2814 advcl determine,generated
R757 T2711 T2710 pobj invertebrates,in
R758 T2815 T2816 det the,functions
R759 T2816 T2813 dobj functions,determine
R760 T2712 T2702 punct .,found
R761 T2817 T2816 amod physiological,functions
R762 T2818 T2816 prep of,functions
R763 T2714 T2715 nsubjpass It,reported
R764 T2819 T2818 pobj ADAM11,of
R765 T2820 T2814 punct ", ",generated
R766 T2821 T2814 nsubj we,generated
R767 T2822 T2814 cc and,generated
R768 T2823 T2814 conj analysed,generated
R769 T2716 T2715 aux has,reported
R770 T2824 T2825 nmod Adam11,mice
R771 T2825 T2823 dobj mice,analysed
R772 T2826 T2827 npadvmod gene,targeted
R773 T2717 T2715 auxpass been,reported
R774 T2827 T2825 amod targeted,mice
R775 T2828 T2827 punct -,targeted
R776 T2829 T2814 punct .,generated
R777 T2718 T2719 mark that,has
R778 T2719 T2715 ccomp has,reported
R779 T2720 T2721 det the,ortholog
R780 T2721 T2719 nsubj ortholog,has
R781 T2722 T2721 compound Xenopus,ortholog
R782 T2723 T2721 compound ADAM11,ortholog
R783 T2724 T2721 punct ", ",ortholog
R784 T2725 T2721 appos xMDC11a,ortholog
R785 T2726 T2719 punct ", ",has
R786 T2727 T2728 det an,pattern
R787 T2728 T2719 dobj pattern,has
R788 T2729 T2728 compound expression,pattern
R789 T2730 T2728 acl associated,pattern
R790 T2731 T2730 prep with,associated
R791 T2732 T2733 amod neural,development
R792 T2733 T2731 pobj development,with
R793 T2734 T2728 punct ", ",pattern
R794 T2735 T2728 prep with,pattern
R795 T2736 T2737 det a,role
R796 T2737 T2735 pobj role,with
R797 T2738 T2737 amod proposed,role
R798 T2739 T2737 prep in,role
R799 T2740 T2741 compound cell,migration
R800 T2741 T2739 pobj migration,in