PMC:1420271 / 7621-8755 JSONTXT 4 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T4450 0-2 PRP denotes We
T4452 3-7 RB denotes also
T4451 8-13 VBD denotes found
T4453 14-18 IN denotes that
T4455 19-22 DT denotes the
T4457 23-26 CD denotes two
T4458 27-30 NN denotes BAC
T4456 31-37 NNS denotes clones
T4454 38-47 VBD denotes contained
T4459 48-55 DT denotes another
T4461 56-60 NN denotes ESG1
T4463 60-61 HYPH denotes -
T4462 61-65 JJ denotes like
T4460 66-74 NN denotes sequence
T4464 75-76 -LRB- denotes (
T4466 76-82 NN denotes Figure
T4465 83-85 NN denotes 2A
T4467 85-86 -RRB- denotes )
T4468 86-87 . denotes .
T4469 87-187 sentence denotes The two sequences, separated by a 68 kbp intergenic sequence, were oriented in opposite directions.
T4470 88-91 DT denotes The
T4472 92-95 CD denotes two
T4471 96-105 NNS denotes sequences
T4474 105-107 , denotes ,
T4475 107-116 VBN denotes separated
T4476 117-119 IN denotes by
T4477 120-121 DT denotes a
T4479 122-124 CD denotes 68
T4480 125-128 NN denotes kbp
T4481 129-139 JJ denotes intergenic
T4478 140-148 NN denotes sequence
T4482 148-150 , denotes ,
T4483 150-154 VBD denotes were
T4473 155-163 VBN denotes oriented
T4484 164-166 IN denotes in
T4485 167-175 JJ denotes opposite
T4486 176-186 NNS denotes directions
T4487 186-187 . denotes .
T4488 187-289 sentence denotes The ESG1-like sequence exhibited greater than 95% identity to the exons and introns of the ESG1 gene.
T4489 188-191 DT denotes The
T4491 192-196 NN denotes ESG1
T4493 196-197 HYPH denotes -
T4492 197-201 JJ denotes like
T4490 202-210 NN denotes sequence
T4494 211-220 VBD denotes exhibited
T4495 221-228 JJR denotes greater
T4497 229-233 IN denotes than
T4496 234-236 CD denotes 95
T4498 236-237 NN denotes %
T4499 238-246 NN denotes identity
T4500 247-249 IN denotes to
T4501 250-253 DT denotes the
T4502 254-259 NNS denotes exons
T4503 260-263 CC denotes and
T4504 264-271 NNS denotes introns
T4505 272-274 IN denotes of
T4506 275-278 DT denotes the
T4508 279-283 NN denotes ESG1
T4507 284-288 NN denotes gene
T4509 288-289 . denotes .
T4510 289-429 sentence denotes This sequence, however, contained critical nucleotide substitutions in all of the exons and one nucleotide insertion in exon 2 (Figure 2B).
T4511 290-294 DT denotes This
T4512 295-303 NN denotes sequence
T4514 303-305 , denotes ,
T4515 305-312 RB denotes however
T4516 312-314 , denotes ,
T4513 314-323 VBD denotes contained
T4517 324-332 JJ denotes critical
T4519 333-343 NN denotes nucleotide
T4518 344-357 NNS denotes substitutions
T4520 358-360 IN denotes in
T4521 361-364 DT denotes all
T4522 365-367 IN denotes of
T4523 368-371 DT denotes the
T4524 372-377 NNS denotes exons
T4525 378-381 CC denotes and
T4526 382-385 CD denotes one
T4528 386-396 NN denotes nucleotide
T4527 397-406 NN denotes insertion
T4529 407-409 IN denotes in
T4530 410-414 NN denotes exon
T4531 415-416 CD denotes 2
T4532 417-418 -LRB- denotes (
T4534 418-424 NN denotes Figure
T4533 425-427 NN denotes 2B
T4535 427-428 -RRB- denotes )
T4536 428-429 . denotes .
T4537 429-600 sentence denotes Although 675 base pairs of the 3' flanking regions were conserved between the ESG1 gene and the pseudogene, only five base pairs of the 5' flanking region were identical.
T4538 430-438 IN denotes Although
T4540 439-442 CD denotes 675
T4542 443-447 NN denotes base
T4541 448-453 NNS denotes pairs
T4543 454-456 IN denotes of
T4544 457-460 DT denotes the
T4546 461-462 CD denotes 3
T4547 462-463 SYM denotes '
T4548 464-472 NN denotes flanking
T4545 473-480 NNS denotes regions
T4549 481-485 VBD denotes were
T4539 486-495 VBN denotes conserved
T4551 496-503 IN denotes between
T4552 504-507 DT denotes the
T4554 508-512 NN denotes ESG1
T4553 513-517 NN denotes gene
T4555 518-521 CC denotes and
T4556 522-525 DT denotes the
T4557 526-536 NN denotes pseudogene
T4558 536-538 , denotes ,
T4559 538-542 RB denotes only
T4561 543-547 CD denotes five
T4562 548-552 NN denotes base
T4560 553-558 NNS denotes pairs
T4563 559-561 IN denotes of
T4564 562-565 DT denotes the
T4566 566-567 CD denotes 5
T4567 567-568 SYM denotes '
T4568 569-577 NN denotes flanking
T4565 578-584 NN denotes region
T4550 585-589 VBD denotes were
T4569 590-599 JJ denotes identical
T4570 599-600 . denotes .
T4571 600-722 sentence denotes This 5' flanking region (~6 kbp) did not possess any promoter/enhancer activity in luciferase reporter assays (Figure 3).
T4572 601-605 DT denotes This
T4574 606-607 CD denotes 5
T4575 607-608 SYM denotes '
T4576 609-617 NN denotes flanking
T4573 618-624 NN denotes region
T4578 625-626 -LRB- denotes (
T4580 626-627 SYM denotes ~
T4581 627-628 CD denotes 6
T4579 629-632 NN denotes kbp
T4582 632-633 -RRB- denotes )
T4583 634-637 VBD denotes did
T4584 638-641 RB denotes not
T4577 642-649 VB denotes possess
T4585 650-653 DT denotes any
T4587 654-662 NN denotes promoter
T4589 662-663 HYPH denotes /
T4588 663-671 NN denotes enhancer
T4586 672-680 NN denotes activity
T4590 681-683 IN denotes in
T4591 684-694 NN denotes luciferase
T4592 695-703 NN denotes reporter
T4593 704-710 NNS denotes assays
T4594 711-712 -LRB- denotes (
T4595 712-718 NN denotes Figure
T4596 719-720 CD denotes 3
T4597 720-721 -RRB- denotes )
T4598 721-722 . denotes .
T4599 722-817 sentence denotes It is thus unlikely that this sequence is transcribed or translated into a functional protein.
T4600 723-725 PRP denotes It
T4601 726-728 VBZ denotes is
T4602 729-733 RB denotes thus
T4603 734-742 JJ denotes unlikely
T4604 743-747 IN denotes that
T4606 748-752 DT denotes this
T4607 753-761 NN denotes sequence
T4608 762-764 VBZ denotes is
T4605 765-776 VBN denotes transcribed
T4609 777-779 CC denotes or
T4610 780-790 VBN denotes translated
T4611 791-795 IN denotes into
T4612 796-797 DT denotes a
T4614 798-808 JJ denotes functional
T4613 809-816 NN denotes protein
T4615 816-817 . denotes .
T4616 817-875 sentence denotes This sequence likely represents a duplication pseudogene.
T4617 818-822 DT denotes This
T4618 823-831 NN denotes sequence
T4620 832-838 RB denotes likely
T4619 839-849 VBZ denotes represents
T4621 850-851 DT denotes a
T4623 852-863 NN denotes duplication
T4622 864-874 NN denotes pseudogene
T4624 874-875 . denotes .
T4625 875-998 sentence denotes Bierbaum previously reported the existence of two pseudogenes with similar exon-intron organization as the ESG1 gene [17].
T4626 876-884 NN denotes Bierbaum
T4628 885-895 RB denotes previously
T4627 896-904 VBD denotes reported
T4629 905-908 DT denotes the
T4630 909-918 NN denotes existence
T4631 919-921 IN denotes of
T4632 922-925 CD denotes two
T4633 926-937 NNS denotes pseudogenes
T4634 938-942 IN denotes with
T4635 943-950 JJ denotes similar
T4637 951-955 NN denotes exon
T4639 955-956 HYPH denotes -
T4638 956-962 NN denotes intron
T4636 963-975 NN denotes organization
T4640 976-978 IN denotes as
T4641 979-982 DT denotes the
T4643 983-987 NN denotes ESG1
T4642 988-992 NN denotes gene
T4644 993-994 -LRB- denotes [
T4645 994-996 CD denotes 17
T4646 996-997 -RRB- denotes ]
T4647 997-998 . denotes .
T4648 998-1134 sentence denotes We could not determine which of these two pseudogenes corresponds to the one we identified or the location of the remaining pseudogene.
T4649 999-1001 PRP denotes We
T4651 1002-1007 MD denotes could
T4652 1008-1011 RB denotes not
T4650 1012-1021 VB denotes determine
T4653 1022-1027 WDT denotes which
T4655 1028-1030 IN denotes of
T4656 1031-1036 DT denotes these
T4658 1037-1040 CD denotes two
T4657 1041-1052 NNS denotes pseudogenes
T4654 1053-1064 VBZ denotes corresponds
T4659 1065-1067 IN denotes to
T4660 1068-1071 DT denotes the
T4661 1072-1075 CD denotes one
T4662 1076-1078 PRP denotes we
T4663 1079-1089 VBD denotes identified
T4664 1090-1092 CC denotes or
T4665 1093-1096 DT denotes the
T4666 1097-1105 NN denotes location
T4667 1106-1108 IN denotes of
T4668 1109-1112 DT denotes the
T4670 1113-1122 VBG denotes remaining
T4669 1123-1133 NN denotes pseudogene
T4671 1133-1134 . denotes .
R1125 T4515 T4513 advmod however,contained
R1126 T4516 T4513 punct ", ",contained
R1127 T4517 T4518 amod critical,substitutions
R1128 T4518 T4513 dobj substitutions,contained
R1129 T4519 T4518 compound nucleotide,substitutions
R1130 T4520 T4513 prep in,contained
R1131 T4521 T4520 pobj all,in
R1132 T4522 T4521 prep of,all
R1133 T4523 T4524 det the,exons
R1134 T4524 T4522 pobj exons,of
R1135 T4525 T4513 cc and,contained
R1136 T4526 T4527 nummod one,insertion
R1137 T4527 T4513 conj insertion,contained
R1138 T4528 T4527 compound nucleotide,insertion
R1139 T4529 T4527 prep in,insertion
R1140 T4530 T4529 pobj exon,in
R1141 T4450 T4451 nsubj We,found
R1142 T4531 T4530 nummod 2,exon
R1143 T4532 T4533 punct (,2B
R1144 T4452 T4451 advmod also,found
R1145 T4453 T4454 mark that,contained
R1146 T4533 T4527 parataxis 2B,insertion
R1147 T4534 T4533 compound Figure,2B
R1148 T4454 T4451 ccomp contained,found
R1149 T4535 T4533 punct ),2B
R1150 T4455 T4456 det the,clones
R1151 T4456 T4454 nsubj clones,contained
R1152 T4536 T4513 punct .,contained
R1153 T4457 T4456 nummod two,clones
R1154 T4458 T4456 compound BAC,clones
R1155 T4459 T4460 det another,sequence
R1156 T4460 T4454 dobj sequence,contained
R1157 T4461 T4462 npadvmod ESG1,like
R1158 T4462 T4460 amod like,sequence
R1159 T4538 T4539 mark Although,conserved
R1160 T4463 T4462 punct -,like
R1161 T4464 T4465 punct (,2A
R1162 T4465 T4454 parataxis 2A,contained
R1163 T4539 T4550 advcl conserved,were
R1164 T4466 T4465 compound Figure,2A
R1165 T4467 T4465 punct ),2A
R1166 T4468 T4451 punct .,found
R1167 T4540 T4541 nummod 675,pairs
R1168 T4470 T4471 det The,sequences
R1169 T4471 T4473 nsubjpass sequences,oriented
R1170 T4541 T4539 nsubjpass pairs,conserved
R1171 T4472 T4471 nummod two,sequences
R1172 T4474 T4471 punct ", ",sequences
R1173 T4542 T4541 compound base,pairs
R1174 T4475 T4471 acl separated,sequences
R1175 T4476 T4475 agent by,separated
R1176 T4543 T4541 prep of,pairs
R1177 T4477 T4478 det a,sequence
R1178 T4478 T4476 pobj sequence,by
R1179 T4479 T4480 nummod 68,kbp
R1180 T4544 T4545 det the,regions
R1181 T4480 T4478 nmod kbp,sequence
R1182 T4481 T4478 amod intergenic,sequence
R1183 T4545 T4543 pobj regions,of
R1184 T4482 T4473 punct ", ",oriented
R1185 T4546 T4545 nummod 3,regions
R1186 T4483 T4473 auxpass were,oriented
R1187 T4484 T4473 prep in,oriented
R1188 T4485 T4486 amod opposite,directions
R1189 T4486 T4484 pobj directions,in
R1190 T4487 T4473 punct .,oriented
R1191 T4547 T4546 punct ',3
R1192 T4489 T4490 det The,sequence
R1193 T4490 T4494 nsubj sequence,exhibited
R1194 T4548 T4545 compound flanking,regions
R1195 T4491 T4492 npadvmod ESG1,like
R1196 T4492 T4490 amod like,sequence
R1197 T4493 T4492 punct -,like
R1198 T4549 T4539 auxpass were,conserved
R1199 T4495 T4496 amod greater,95
R1200 T4496 T4498 nummod 95,%
R1201 T4551 T4539 prep between,conserved
R1202 T4497 T4496 quantmod than,95
R1203 T4498 T4499 compound %,identity
R1204 T4499 T4494 dobj identity,exhibited
R1205 T4500 T4499 prep to,identity
R1206 T4552 T4553 det the,gene
R1207 T4501 T4502 det the,exons
R1208 T4502 T4500 pobj exons,to
R1209 T4503 T4502 cc and,exons
R1210 T4504 T4502 conj introns,exons
R1211 T4505 T4502 prep of,exons
R1212 T4553 T4551 pobj gene,between
R1213 T4506 T4507 det the,gene
R1214 T4507 T4505 pobj gene,of
R1215 T4508 T4507 compound ESG1,gene
R1216 T4554 T4553 compound ESG1,gene
R1217 T4509 T4494 punct .,exhibited
R1218 T4511 T4512 det This,sequence
R1219 T4555 T4553 cc and,gene
R1220 T4512 T4513 nsubj sequence,contained
R1221 T4556 T4557 det the,pseudogene
R1222 T4514 T4513 punct ", ",contained
R1223 T4557 T4553 conj pseudogene,gene
R1224 T4558 T4550 punct ", ",were
R1225 T4559 T4560 advmod only,pairs
R1226 T4621 T4622 det a,pseudogene
R1227 T4560 T4550 nsubj pairs,were
R1228 T4622 T4619 dobj pseudogene,represents
R1229 T4623 T4622 compound duplication,pseudogene
R1230 T4624 T4619 punct .,represents
R1231 T4561 T4560 nummod five,pairs
R1232 T4626 T4627 nsubj Bierbaum,reported
R1233 T4562 T4560 compound base,pairs
R1234 T4628 T4627 advmod previously,reported
R1235 T4629 T4630 det the,existence
R1236 T4563 T4560 prep of,pairs
R1237 T4630 T4627 dobj existence,reported
R1238 T4631 T4630 prep of,existence
R1239 T4632 T4633 nummod two,pseudogenes
R1240 T4564 T4565 det the,region
R1241 T4633 T4631 pobj pseudogenes,of
R1242 T4565 T4563 pobj region,of
R1243 T4634 T4633 prep with,pseudogenes
R1244 T4566 T4565 nummod 5,region
R1245 T4635 T4636 amod similar,organization
R1246 T4567 T4566 punct ',5
R1247 T4636 T4634 pobj organization,with
R1248 T4637 T4638 compound exon,intron
R1249 T4568 T4565 compound flanking,region
R1250 T4638 T4636 compound intron,organization
R1251 T4639 T4638 punct -,intron
R1252 T4640 T4627 prep as,reported
R1253 T4569 T4550 acomp identical,were
R1254 T4641 T4642 det the,gene
R1255 T4642 T4640 pobj gene,as
R1256 T4643 T4642 compound ESG1,gene
R1257 T4570 T4550 punct .,were
R1258 T4644 T4645 punct [,17
R1259 T4645 T4627 parataxis 17,reported
R1260 T4646 T4645 punct ],17
R1261 T4647 T4627 punct .,reported
R1262 T4572 T4573 det This,region
R1263 T4649 T4650 nsubj We,determine
R1264 T4651 T4650 aux could,determine
R1265 T4573 T4577 nsubj region,possess
R1266 T4652 T4650 neg not,determine
R1267 T4653 T4654 dep which,corresponds
R1268 T4654 T4650 ccomp corresponds,determine
R1269 T4574 T4573 nummod 5,region
R1270 T4655 T4653 prep of,which
R1271 T4656 T4657 det these,pseudogenes
R1272 T4575 T4574 punct ',5
R1273 T4657 T4655 pobj pseudogenes,of
R1274 T4658 T4657 nummod two,pseudogenes
R1275 T4576 T4573 compound flanking,region
R1276 T4659 T4654 prep to,corresponds
R1277 T4660 T4661 det the,one
R1278 T4661 T4659 pobj one,to
R1279 T4578 T4579 punct (,kbp
R1280 T4662 T4663 nsubj we,identified
R1281 T4663 T4661 advcl identified,one
R1282 T4664 T4661 cc or,one
R1283 T4665 T4666 det the,location
R1284 T4579 T4573 parataxis kbp,region
R1285 T4666 T4661 conj location,one
R1286 T4667 T4666 prep of,location
R1287 T4668 T4669 det the,pseudogene
R1288 T4580 T4581 punct ~,6
R1289 T4669 T4667 pobj pseudogene,of
R1290 T4670 T4669 amod remaining,pseudogene
R1291 T4671 T4650 punct .,determine
R1292 T4581 T4579 nummod 6,kbp
R1293 T4582 T4579 punct ),kbp
R1294 T4583 T4577 aux did,possess
R1295 T4584 T4577 neg not,possess
R1296 T4585 T4586 det any,activity
R1297 T4586 T4577 dobj activity,possess
R1298 T4587 T4588 compound promoter,enhancer
R1299 T4588 T4586 compound enhancer,activity
R1300 T4589 T4588 punct /,enhancer
R1301 T4590 T4577 prep in,possess
R1302 T4591 T4592 compound luciferase,reporter
R1303 T4592 T4593 compound reporter,assays
R1304 T4593 T4590 pobj assays,in
R1305 T4594 T4595 punct (,Figure
R1306 T4595 T4577 parataxis Figure,possess
R1307 T4596 T4595 nummod 3,Figure
R1308 T4597 T4595 punct ),Figure
R1309 T4598 T4577 punct .,possess
R1310 T4600 T4601 nsubj It,is
R1311 T4602 T4601 advmod thus,is
R1312 T4603 T4601 acomp unlikely,is
R1313 T4604 T4605 mark that,transcribed
R1314 T4605 T4601 ccomp transcribed,is
R1315 T4606 T4607 det this,sequence
R1316 T4607 T4605 nsubjpass sequence,transcribed
R1317 T4608 T4605 auxpass is,transcribed
R1318 T4609 T4605 cc or,transcribed
R1319 T4610 T4605 conj translated,transcribed
R1320 T4611 T4610 prep into,translated
R1321 T4612 T4613 det a,protein
R1322 T4613 T4611 pobj protein,into
R1323 T4614 T4613 amod functional,protein
R1324 T4615 T4601 punct .,is
R1325 T4617 T4618 det This,sequence
R1326 T4618 T4619 nsubj sequence,represents
R1327 T4620 T4619 advmod likely,represents