PMC:138691 / 5550-7457 JSONTXT 4 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T1386 0-5 IN denotes While
T1388 6-14 NNP denotes Moynahan
T1389 15-17 FW denotes et
T1390 18-20 FW denotes al
T1387 21-25 VBD denotes were
T1392 26-33 JJ denotes careful
T1393 34-36 TO denotes to
T1394 37-42 VB denotes point
T1395 43-46 RP denotes out
T1396 47-51 DT denotes this
T1397 52-59 NN denotes problem
T1398 59-61 , denotes ,
T1399 61-64 CD denotes two
T1400 65-69 NNS denotes sets
T1401 70-72 IN denotes of
T1402 73-80 NNS denotes results
T1391 81-86 VBP denotes argue
T1403 87-94 IN denotes against
T1404 95-98 DT denotes the
T1405 99-110 NN denotes possibility
T1406 111-115 IN denotes that
T1408 116-119 DT denotes the
T1410 120-135 JJ denotes recombinational
T1411 136-142 NN denotes repair
T1409 143-153 NN denotes deficiency
T1412 154-156 IN denotes of
T1413 157-162 NN denotes CAPAN
T1415 162-163 HYPH denotes -
T1416 163-164 CD denotes 1
T1414 165-170 NNS denotes cells
T1407 171-173 VBZ denotes is
T1417 174-184 RB denotes completely
T1418 185-196 JJ denotes independent
T1419 197-199 IN denotes of
T1420 200-203 PRP$ denotes its
T1421 204-210 NN denotes defect
T1422 211-213 IN denotes in
T1423 214-219 NN denotes BRCA2
T1424 219-220 . denotes .
T1425 220-347 sentence denotes First, in the same study [24], recombination in a mouse ES cell line that expresses only truncated BRCA2 protein was measured.
T1426 221-226 RB denotes First
T1428 226-228 , denotes ,
T1429 228-230 IN denotes in
T1430 231-234 DT denotes the
T1432 235-239 JJ denotes same
T1431 240-245 NN denotes study
T1433 246-247 -LRB- denotes [
T1434 247-249 CD denotes 24
T1435 249-250 -RRB- denotes ]
T1436 250-252 , denotes ,
T1437 252-265 NN denotes recombination
T1438 266-268 IN denotes in
T1439 269-270 DT denotes a
T1441 271-276 NN denotes mouse
T1442 277-279 NN denotes ES
T1443 280-284 NN denotes cell
T1440 285-289 NN denotes line
T1444 290-294 WDT denotes that
T1445 295-304 VBZ denotes expresses
T1446 305-309 RB denotes only
T1448 310-319 VBN denotes truncated
T1449 320-325 NN denotes BRCA2
T1447 326-333 NN denotes protein
T1450 334-337 VBD denotes was
T1427 338-346 VBN denotes measured
T1451 346-347 . denotes .
T1452 347-508 sentence denotes This line was found to have lower recombination efficiency than isogenic cells expressing full-length BRCA2 (the defect observed was about fivefold to sixfold).
T1453 348-352 DT denotes This
T1454 353-357 NN denotes line
T1456 358-361 VBD denotes was
T1455 362-367 VBN denotes found
T1457 368-370 TO denotes to
T1458 371-375 VB denotes have
T1459 376-381 JJR denotes lower
T1461 382-395 NN denotes recombination
T1460 396-406 NN denotes efficiency
T1462 407-411 IN denotes than
T1463 412-420 JJ denotes isogenic
T1464 421-426 NNS denotes cells
T1465 427-437 VBG denotes expressing
T1466 438-442 JJ denotes full
T1468 442-443 HYPH denotes -
T1467 443-449 NN denotes length
T1469 450-455 NN denotes BRCA2
T1470 456-457 -LRB- denotes (
T1472 457-460 DT denotes the
T1473 461-467 NN denotes defect
T1474 468-476 VBN denotes observed
T1471 477-480 VBD denotes was
T1475 481-486 RB denotes about
T1477 487-495 RB denotes fivefold
T1478 496-498 IN denotes to
T1476 499-506 RB denotes sixfold
T1479 506-507 -RRB- denotes )
T1480 507-508 . denotes .
T1481 508-707 sentence denotes Second, in an independent study, Powell was able to compare derivatives of CAPAN-1 that differed only in their ability to express full-length BRCA2 protein (S. Powell, personal communication, 2001).
T1482 509-515 RB denotes Second
T1484 515-517 , denotes ,
T1485 517-519 IN denotes in
T1486 520-522 DT denotes an
T1488 523-534 JJ denotes independent
T1487 535-540 NN denotes study
T1489 540-542 , denotes ,
T1490 542-548 NNP denotes Powell
T1483 549-552 VBD denotes was
T1491 553-557 JJ denotes able
T1492 558-560 TO denotes to
T1493 561-568 VB denotes compare
T1494 569-580 NNS denotes derivatives
T1495 581-583 IN denotes of
T1496 584-589 NN denotes CAPAN
T1497 589-590 HYPH denotes -
T1498 590-591 CD denotes 1
T1499 592-596 WDT denotes that
T1500 597-605 VBD denotes differed
T1501 606-610 RB denotes only
T1502 611-613 IN denotes in
T1503 614-619 PRP$ denotes their
T1504 620-627 NN denotes ability
T1505 628-630 TO denotes to
T1506 631-638 VB denotes express
T1507 639-643 JJ denotes full
T1509 643-644 HYPH denotes -
T1508 644-650 NN denotes length
T1511 651-656 NN denotes BRCA2
T1510 657-664 NN denotes protein
T1512 665-666 -LRB- denotes (
T1514 666-668 NNP denotes S.
T1513 669-675 NNP denotes Powell
T1515 675-677 , denotes ,
T1516 677-685 JJ denotes personal
T1517 686-699 NN denotes communication
T1518 699-701 , denotes ,
T1519 701-705 CD denotes 2001
T1520 705-706 -RRB- denotes )
T1521 706-707 . denotes .
T1522 707-896 sentence denotes In these experiments, the derivative expressing full-length BRCA2 yielded 10-fold more recombinants than controls expressing only truncated BRCA2 (S. Powell, personal communication, 2001).
T1523 708-710 IN denotes In
T1525 711-716 DT denotes these
T1526 717-728 NNS denotes experiments
T1527 728-730 , denotes ,
T1528 730-733 DT denotes the
T1529 734-744 NN denotes derivative
T1530 745-755 VBG denotes expressing
T1531 756-760 JJ denotes full
T1533 760-761 HYPH denotes -
T1532 761-767 NN denotes length
T1534 768-773 NN denotes BRCA2
T1524 774-781 VBD denotes yielded
T1535 782-789 RB denotes 10-fold
T1536 790-794 JJR denotes more
T1537 795-807 NNS denotes recombinants
T1538 808-812 IN denotes than
T1539 813-821 NNS denotes controls
T1540 822-832 VBG denotes expressing
T1541 833-837 RB denotes only
T1543 838-847 VBN denotes truncated
T1542 848-853 NN denotes BRCA2
T1544 854-855 -LRB- denotes (
T1546 855-857 NNP denotes S.
T1545 858-864 NNP denotes Powell
T1547 864-866 , denotes ,
T1548 866-874 JJ denotes personal
T1549 875-888 NN denotes communication
T1550 888-890 , denotes ,
T1551 890-894 CD denotes 2001
T1552 894-895 -RRB- denotes )
T1553 895-896 . denotes .
T1554 896-1192 sentence denotes While the experimental design of these experiments was somewhat different from that of Moyna-han et al [24], the results raise the possibility that CAPAN-1 cells have more than one mutation that lowers the efficiency of recombinational repair relative to that observed in other human cell lines.
T1555 897-902 IN denotes While
T1557 903-906 DT denotes the
T1559 907-919 JJ denotes experimental
T1558 920-926 NN denotes design
T1560 927-929 IN denotes of
T1561 930-935 DT denotes these
T1562 936-947 NNS denotes experiments
T1556 948-951 VBD denotes was
T1564 952-960 RB denotes somewhat
T1565 961-970 JJ denotes different
T1566 971-975 IN denotes from
T1567 976-980 DT denotes that
T1568 981-983 IN denotes of
T1569 984-989 NNP denotes Moyna
T1571 989-990 HYPH denotes -
T1570 990-993 NNP denotes han
T1572 994-996 FW denotes et
T1573 997-999 FW denotes al
T1574 1000-1001 -LRB- denotes [
T1575 1001-1003 CD denotes 24
T1576 1003-1004 -RRB- denotes ]
T1577 1004-1006 , denotes ,
T1578 1006-1009 DT denotes the
T1579 1010-1017 NNS denotes results
T1563 1018-1023 VBP denotes raise
T1580 1024-1027 DT denotes the
T1581 1028-1039 NN denotes possibility
T1582 1040-1044 IN denotes that
T1584 1045-1050 NN denotes CAPAN
T1586 1050-1051 HYPH denotes -
T1587 1051-1052 CD denotes 1
T1585 1053-1058 NNS denotes cells
T1583 1059-1063 VBP denotes have
T1588 1064-1068 JJR denotes more
T1590 1069-1073 IN denotes than
T1589 1074-1077 CD denotes one
T1591 1078-1086 NN denotes mutation
T1592 1087-1091 WDT denotes that
T1593 1092-1098 VBZ denotes lowers
T1594 1099-1102 DT denotes the
T1595 1103-1113 NN denotes efficiency
T1596 1114-1116 IN denotes of
T1597 1117-1132 JJ denotes recombinational
T1598 1133-1139 NN denotes repair
T1599 1140-1148 JJ denotes relative
T1600 1149-1151 IN denotes to
T1601 1152-1156 DT denotes that
T1602 1157-1165 VBN denotes observed
T1603 1166-1168 IN denotes in
T1604 1169-1174 JJ denotes other
T1606 1175-1180 JJ denotes human
T1607 1181-1185 NN denotes cell
T1605 1186-1191 NNS denotes lines
T1608 1191-1192 . denotes .
T1609 1192-1373 sentence denotes Conversely, the BRCA2 defect in CAPAN-1 could be fully responsible for the 100-fold defect in recombination if the level of BRCA2 complementation observed by Powell was incomplete.
T1610 1193-1203 RB denotes Conversely
T1612 1203-1205 , denotes ,
T1613 1205-1208 DT denotes the
T1615 1209-1214 NN denotes BRCA2
T1614 1215-1221 NN denotes defect
T1616 1222-1224 IN denotes in
T1617 1225-1230 NN denotes CAPAN
T1618 1230-1231 HYPH denotes -
T1619 1231-1232 CD denotes 1
T1620 1233-1238 MD denotes could
T1611 1239-1241 VB denotes be
T1621 1242-1247 RB denotes fully
T1622 1248-1259 JJ denotes responsible
T1623 1260-1263 IN denotes for
T1624 1264-1267 DT denotes the
T1626 1268-1276 JJ denotes 100-fold
T1625 1277-1283 NN denotes defect
T1627 1284-1286 IN denotes in
T1628 1287-1300 NN denotes recombination
T1629 1301-1303 IN denotes if
T1631 1304-1307 DT denotes the
T1632 1308-1313 NN denotes level
T1633 1314-1316 IN denotes of
T1634 1317-1322 NN denotes BRCA2
T1635 1323-1338 NN denotes complementation
T1636 1339-1347 VBN denotes observed
T1637 1348-1350 IN denotes by
T1638 1351-1357 NNP denotes Powell
T1630 1358-1361 VBD denotes was
T1639 1362-1372 JJ denotes incomplete
T1640 1372-1373 . denotes .
T1641 1373-1666 sentence denotes Furthermore, the discrepancy between the 100-fold difference between CAPAN-1 and the other human lines as compared with the fivefold to sixfold difference between the Brca2lex1/lex2cells and Brca2+/+ ES cells might simply be accounted for by the fact that Brca2lex1/lex2 is not a null allele.
T1642 1374-1385 RB denotes Furthermore
T1644 1385-1387 , denotes ,
T1645 1387-1390 DT denotes the
T1646 1391-1402 NN denotes discrepancy
T1647 1403-1410 IN denotes between
T1648 1411-1414 DT denotes the
T1650 1415-1423 JJ denotes 100-fold
T1649 1424-1434 NN denotes difference
T1651 1435-1442 IN denotes between
T1652 1443-1448 NN denotes CAPAN
T1653 1448-1449 HYPH denotes -
T1654 1449-1450 CD denotes 1
T1655 1451-1454 CC denotes and
T1656 1455-1458 DT denotes the
T1658 1459-1464 JJ denotes other
T1659 1465-1470 JJ denotes human
T1657 1471-1476 NNS denotes lines
T1660 1477-1479 IN denotes as
T1661 1480-1488 VBN denotes compared
T1662 1489-1493 IN denotes with
T1663 1494-1497 DT denotes the
T1665 1498-1506 JJ denotes fivefold
T1667 1507-1509 IN denotes to
T1666 1510-1517 JJ denotes sixfold
T1664 1518-1528 NN denotes difference
T1668 1529-1536 IN denotes between
T1669 1537-1540 DT denotes the
T1671 1541-1550 NN denotes Brca2lex1
T1673 1550-1551 HYPH denotes /
T1672 1551-1555 NN denotes lex2
T1670 1555-1560 NNS denotes cells
T1674 1561-1564 CC denotes and
T1675 1565-1570 NN denotes Brca2
T1677 1570-1571 SYM denotes +
T1678 1571-1572 HYPH denotes /
T1679 1572-1573 SYM denotes +
T1680 1574-1576 NN denotes ES
T1676 1577-1582 NNS denotes cells
T1681 1583-1588 MD denotes might
T1682 1589-1595 RB denotes simply
T1683 1596-1598 VB denotes be
T1643 1599-1608 VBN denotes accounted
T1684 1609-1612 IN denotes for
T1685 1613-1615 IN denotes by
T1686 1616-1619 DT denotes the
T1687 1620-1624 NN denotes fact
T1688 1625-1629 IN denotes that
T1690 1630-1639 NN denotes Brca2lex1
T1692 1639-1640 HYPH denotes /
T1691 1640-1644 NN denotes lex2
T1689 1645-1647 VBZ denotes is
T1693 1648-1651 RB denotes not
T1694 1652-1653 DT denotes a
T1696 1654-1658 JJ denotes null
T1695 1659-1665 NN denotes allele
T1697 1665-1666 . denotes .
T1698 1666-1773 sentence denotes Additional studies are likely to shed light on the efficiency of BRCA2-independent recombination pathways.
T1699 1667-1677 JJ denotes Additional
T1700 1678-1685 NNS denotes studies
T1701 1686-1689 VBP denotes are
T1702 1690-1696 JJ denotes likely
T1703 1697-1699 TO denotes to
T1704 1700-1704 VB denotes shed
T1705 1705-1710 NN denotes light
T1706 1711-1713 IN denotes on
T1707 1714-1717 DT denotes the
T1708 1718-1728 NN denotes efficiency
T1709 1729-1731 IN denotes of
T1710 1732-1737 NN denotes BRCA2
T1712 1737-1738 HYPH denotes -
T1711 1738-1749 JJ denotes independent
T1714 1750-1763 NN denotes recombination
T1713 1764-1772 NNS denotes pathways
T1715 1772-1773 . denotes .
T1716 1773-1907 sentence denotes Taken together, the results indicate that BRCA2 is indeed required for high levels of recombinational repair in both human and mouse.
T1717 1774-1779 VBN denotes Taken
T1719 1780-1788 RB denotes together
T1720 1788-1790 , denotes ,
T1721 1790-1793 DT denotes the
T1722 1794-1801 NNS denotes results
T1718 1802-1810 VBP denotes indicate
T1723 1811-1815 IN denotes that
T1725 1816-1821 NN denotes BRCA2
T1726 1822-1824 VBZ denotes is
T1727 1825-1831 RB denotes indeed
T1724 1832-1840 VBN denotes required
T1728 1841-1844 IN denotes for
T1729 1845-1849 JJ denotes high
T1730 1850-1856 NNS denotes levels
T1731 1857-1859 IN denotes of
T1732 1860-1875 JJ denotes recombinational
T1733 1876-1882 NN denotes repair
T1734 1883-1885 IN denotes in
T1735 1886-1890 CC denotes both
T1737 1891-1896 JJ denotes human
T1738 1897-1900 CC denotes and
T1736 1901-1906 NN denotes mouse
T1739 1906-1907 . denotes .
R1000 T1467 T1469 compound length,BRCA2
R1001 T1468 T1467 punct -,length
R1002 T1469 T1465 dobj BRCA2,expressing
R1003 T1470 T1471 punct (,was
R1004 T1471 T1469 parataxis was,BRCA2
R1005 T1472 T1473 det the,defect
R1006 T1473 T1471 nsubj defect,was
R1007 T1474 T1473 acl observed,defect
R1008 T1475 T1476 advmod about,sixfold
R1009 T1476 T1471 advmod sixfold,was
R1010 T1477 T1476 advmod fivefold,sixfold
R1011 T1478 T1476 quantmod to,sixfold
R1012 T1479 T1471 punct ),was
R1013 T1480 T1455 punct .,found
R1014 T1482 T1483 advmod Second,was
R1015 T1484 T1483 punct ", ",was
R1016 T1485 T1483 prep in,was
R1017 T1486 T1487 det an,study
R1018 T1487 T1485 pobj study,in
R1019 T1488 T1487 amod independent,study
R1020 T1489 T1483 punct ", ",was
R1021 T1490 T1483 nsubj Powell,was
R1022 T1491 T1483 acomp able,was
R1023 T1492 T1493 aux to,compare
R1024 T1493 T1491 xcomp compare,able
R1025 T1494 T1493 dobj derivatives,compare
R1026 T1495 T1494 prep of,derivatives
R1027 T1496 T1495 pobj CAPAN,of
R1028 T1497 T1496 punct -,CAPAN
R1029 T1498 T1496 nummod 1,CAPAN
R1030 T1499 T1500 dep that,differed
R1031 T1500 T1494 relcl differed,derivatives
R1032 T1501 T1500 advmod only,differed
R1033 T1502 T1500 prep in,differed
R1034 T1503 T1504 poss their,ability
R1035 T1504 T1502 pobj ability,in
R1036 T1505 T1506 aux to,express
R1037 T1506 T1504 acl express,ability
R1038 T1507 T1508 amod full,length
R1039 T1508 T1510 compound length,protein
R1040 T1509 T1508 punct -,length
R1041 T1510 T1506 dobj protein,express
R1042 T1511 T1510 compound BRCA2,protein
R1043 T1512 T1513 punct (,Powell
R1044 T1513 T1493 meta Powell,compare
R1045 T1514 T1513 compound S.,Powell
R1046 T1515 T1513 punct ", ",Powell
R1047 T1516 T1517 amod personal,communication
R1048 T1517 T1513 dep communication,Powell
R1049 T1518 T1513 punct ", ",Powell
R1050 T1519 T1513 npadvmod 2001,Powell
R1051 T1520 T1513 punct ),Powell
R1052 T1521 T1483 punct .,was
R1053 T1523 T1524 prep In,yielded
R1054 T1525 T1526 det these,experiments
R1055 T1526 T1523 pobj experiments,In
R1056 T1527 T1524 punct ", ",yielded
R1057 T1528 T1529 det the,derivative
R1058 T1529 T1524 nsubj derivative,yielded
R1059 T1530 T1529 acl expressing,derivative
R1060 T1531 T1532 amod full,length
R1061 T1532 T1534 compound length,BRCA2
R1062 T1533 T1532 punct -,length
R1063 T1534 T1530 dobj BRCA2,expressing
R1064 T1535 T1536 advmod 10-fold,more
R1065 T1536 T1537 amod more,recombinants
R1066 T1537 T1524 dobj recombinants,yielded
R1067 T1538 T1537 prep than,recombinants
R1068 T1539 T1538 pobj controls,than
R1069 T1540 T1539 acl expressing,controls
R1070 T1541 T1542 advmod only,BRCA2
R1071 T1542 T1540 dobj BRCA2,expressing
R1072 T1543 T1542 amod truncated,BRCA2
R1073 T1544 T1545 punct (,Powell
R1074 T1545 T1524 meta Powell,yielded
R1075 T1546 T1545 compound S.,Powell
R1076 T1547 T1545 punct ", ",Powell
R1077 T1548 T1549 amod personal,communication
R1078 T1549 T1545 dep communication,Powell
R1079 T1550 T1545 punct ", ",Powell
R1080 T1551 T1545 dep 2001,Powell
R1081 T1552 T1545 punct ),Powell
R1082 T1553 T1524 punct .,yielded
R1083 T1555 T1556 mark While,was
R1084 T1556 T1563 advcl was,raise
R1085 T1557 T1558 det the,design
R1086 T1558 T1556 nsubj design,was
R1087 T1559 T1558 amod experimental,design
R1088 T1560 T1558 prep of,design
R1089 T1561 T1562 det these,experiments
R1090 T1562 T1560 pobj experiments,of
R1091 T1564 T1565 advmod somewhat,different
R1092 T1565 T1556 acomp different,was
R1093 T1566 T1565 prep from,different
R1094 T1567 T1566 pobj that,from
R1095 T1568 T1567 prep of,that
R1096 T1569 T1570 compound Moyna,han
R1097 T1570 T1568 pobj han,of
R1098 T1571 T1570 punct -,han
R1099 T1572 T1573 advmod et,al
R1100 T1573 T1570 advmod al,han
R1101 T1574 T1575 punct [,24
R1102 T1575 T1570 parataxis 24,han
R1103 T1576 T1575 punct ],24
R1104 T1577 T1563 punct ", ",raise
R1105 T1578 T1579 det the,results
R1106 T1579 T1563 nsubj results,raise
R1107 T1580 T1581 det the,possibility
R1108 T1581 T1563 dobj possibility,raise
R1109 T1582 T1583 mark that,have
R1110 T1583 T1581 acl have,possibility
R1111 T1584 T1585 nmod CAPAN,cells
R1112 T1585 T1583 nsubj cells,have
R1113 T1586 T1584 punct -,CAPAN
R1114 T1587 T1584 nummod 1,CAPAN
R1115 T1588 T1589 amod more,one
R1116 T1589 T1591 nummod one,mutation
R1117 T1590 T1589 quantmod than,one
R1118 T1591 T1583 dobj mutation,have
R1119 T1592 T1593 dep that,lowers
R1120 T1593 T1591 relcl lowers,mutation
R1121 T1594 T1595 det the,efficiency
R1122 T1595 T1593 dobj efficiency,lowers
R1123 T1596 T1595 prep of,efficiency
R1124 T1597 T1598 amod recombinational,repair
R1125 T1598 T1596 pobj repair,of
R1126 T1599 T1598 amod relative,repair
R1127 T1600 T1599 prep to,relative
R1128 T1601 T1600 pobj that,to
R1129 T1602 T1601 acl observed,that
R1130 T1603 T1602 prep in,observed
R1131 T1604 T1605 amod other,lines
R1132 T1605 T1603 pobj lines,in
R1133 T1606 T1605 amod human,lines
R1134 T1607 T1605 compound cell,lines
R1135 T1608 T1563 punct .,raise
R1136 T1610 T1611 advmod Conversely,be
R1137 T1612 T1611 punct ", ",be
R1138 T1613 T1614 det the,defect
R1139 T1614 T1611 nsubj defect,be
R1140 T1615 T1614 compound BRCA2,defect
R1141 T1616 T1614 prep in,defect
R1142 T1617 T1616 pobj CAPAN,in
R1143 T1618 T1617 punct -,CAPAN
R1144 T1619 T1617 nummod 1,CAPAN
R1145 T1621 T1622 advmod fully,responsible
R1146 T1622 T1611 acomp responsible,be
R1147 T1623 T1622 prep for,responsible
R1148 T1624 T1625 det the,defect
R1149 T1625 T1623 pobj defect,for
R1150 T1620 T1611 aux could,be
R1151 T1627 T1625 prep in,defect
R1152 T1628 T1627 pobj recombination,in
R1153 T1626 T1625 amod 100-fold,defect
R1154 T1630 T1611 advcl was,be
R1155 T1631 T1632 det the,level
R1156 T1629 T1630 mark if,was
R1157 T1633 T1632 prep of,level
R1158 T1634 T1635 compound BRCA2,complementation
R1159 T1632 T1630 nsubj level,was
R1160 T1636 T1632 acl observed,level
R1161 T1637 T1636 agent by,observed
R1162 T1638 T1637 pobj Powell,by
R1163 T1639 T1630 acomp incomplete,was
R1164 T1635 T1633 pobj complementation,of
R1165 T1642 T1643 advmod Furthermore,accounted
R1166 T1640 T1611 punct .,be
R1167 T1644 T1643 punct ", ",accounted
R1168 T1645 T1646 det the,discrepancy
R1169 T1647 T1646 prep between,discrepancy
R1170 T1648 T1649 det the,difference
R1171 T1646 T1643 nsubjpass discrepancy,accounted
R1172 T1650 T1649 amod 100-fold,difference
R1173 T1651 T1649 prep between,difference
R1174 T1649 T1647 pobj difference,between
R1175 T1653 T1652 punct -,CAPAN
R1176 T1654 T1652 nummod 1,CAPAN
R1177 T1652 T1651 pobj CAPAN,between
R1178 T1656 T1657 det the,lines
R1179 T1657 T1652 conj lines,CAPAN
R1180 T1655 T1652 cc and,CAPAN
R1181 T1659 T1657 amod human,lines
R1182 T1660 T1646 prep as,discrepancy
R1183 T1658 T1657 amod other,lines
R1184 T1662 T1661 prep with,compared
R1185 T1661 T1660 prep compared,as
R1186 T1664 T1662 pobj difference,with
R1187 T1663 T1664 det the,difference
R1188 T1666 T1664 nummod sixfold,difference
R1189 T1665 T1666 amod fivefold,sixfold
R1190 T1668 T1664 prep between,difference
R1191 T1669 T1670 det the,cells
R1192 T1667 T1666 quantmod to,sixfold
R1193 T1671 T1672 compound Brca2lex1,lex2
R1194 T1672 T1670 compound lex2,cells
R1195 T1670 T1668 pobj cells,between
R1196 T1674 T1670 cc and,cells
R1197 T1675 T1676 nmod Brca2,cells
R1198 T1673 T1672 punct /,lex2
R1199 T1677 T1675 punct +,Brca2
R1200 T1678 T1675 punct /,Brca2
R1201 T1679 T1675 punct +,Brca2
R1202 T1676 T1670 conj cells,cells
R1203 T1681 T1643 aux might,accounted
R1204 T1682 T1643 advmod simply,accounted
R1205 T1680 T1676 compound ES,cells
R1206 T1684 T1643 prep for,accounted
R1207 T1685 T1643 prep by,accounted
R1208 T1683 T1643 auxpass be,accounted
R1209 T1687 T1685 pobj fact,by
R1210 T1688 T1689 mark that,is
R1211 T1686 T1687 det the,fact
R1212 T1690 T1691 compound Brca2lex1,lex2
R1213 T1691 T1689 nsubj lex2,is
R1214 T1689 T1687 acl is,fact
R1215 T1693 T1689 neg not,is
R1216 T1694 T1695 det a,allele
R1217 T1692 T1691 punct /,lex2
R1218 T1696 T1695 amod null,allele
R1219 T1697 T1643 punct .,accounted
R1220 T1695 T1689 attr allele,is
R1221 T1699 T1700 amod Additional,studies
R1222 T1700 T1701 nsubj studies,are
R1223 T1702 T1701 acomp likely,are
R1224 T1704 T1702 xcomp shed,likely
R1225 T1705 T1704 dobj light,shed
R1226 T1703 T1704 aux to,shed
R1227 T1707 T1708 det the,efficiency
R1228 T1708 T1706 pobj efficiency,on
R1229 T1706 T1704 prep on,shed
R1230 T1710 T1711 npadvmod BRCA2,independent
R1231 T1711 T1713 amod independent,pathways
R1232 T1709 T1708 prep of,efficiency
R1233 T1713 T1709 pobj pathways,of
R1234 T1714 T1713 compound recombination,pathways
R1235 T1712 T1711 punct -,independent
R1236 T1719 T1717 advmod together,Taken
R1237 T1715 T1701 punct .,are
R1238 T1720 T1718 punct ", ",indicate
R1239 T1717 T1718 advcl Taken,indicate
R1240 T1722 T1718 nsubj results,indicate
R1241 T1721 T1722 det the,results
R1242 T1724 T1718 ccomp required,indicate
R1243 T1725 T1724 nsubjpass BRCA2,required
R1244 T1723 T1724 mark that,required
R1245 T1727 T1724 advmod indeed,required
R1246 T1728 T1724 prep for,required
R1247 T1726 T1724 auxpass is,required
R1248 T1730 T1728 pobj levels,for
R1249 T1729 T1730 amod high,levels
R1250 T1732 T1733 amod recombinational,repair
R1251 T1733 T1731 pobj repair,of
R1252 T1731 T1730 prep of,levels
R1253 T1735 T1736 preconj both,mouse
R1254 T1734 T1724 prep in,required
R1255 T1737 T1736 amod human,mouse
R1256 T1738 T1736 cc and,mouse
R1257 T1736 T1734 pobj mouse,in
R1258 T1739 T1718 punct .,indicate
R924 T1386 T1387 mark While,were
R925 T1387 T1391 advcl were,argue
R926 T1388 T1387 nsubj Moynahan,were
R927 T1389 T1390 advmod et,al
R928 T1390 T1388 advmod al,Moynahan
R929 T1392 T1387 acomp careful,were
R930 T1393 T1394 aux to,point
R931 T1394 T1392 xcomp point,careful
R932 T1395 T1394 prt out,point
R933 T1396 T1397 det this,problem
R934 T1397 T1394 dobj problem,point
R935 T1398 T1391 punct ", ",argue
R936 T1399 T1400 nummod two,sets
R937 T1400 T1391 nsubj sets,argue
R938 T1401 T1400 prep of,sets
R939 T1402 T1401 pobj results,of
R940 T1403 T1391 prep against,argue
R941 T1404 T1405 det the,possibility
R942 T1405 T1403 pobj possibility,against
R943 T1406 T1407 mark that,is
R944 T1407 T1405 acl is,possibility
R945 T1408 T1409 det the,deficiency
R946 T1409 T1407 nsubj deficiency,is
R947 T1410 T1409 amod recombinational,deficiency
R948 T1411 T1409 compound repair,deficiency
R949 T1412 T1409 prep of,deficiency
R950 T1413 T1414 nmod CAPAN,cells
R951 T1414 T1412 pobj cells,of
R952 T1415 T1413 punct -,CAPAN
R953 T1416 T1413 nummod 1,CAPAN
R954 T1417 T1418 advmod completely,independent
R955 T1418 T1407 acomp independent,is
R956 T1419 T1418 prep of,independent
R957 T1420 T1421 poss its,defect
R958 T1421 T1419 pobj defect,of
R959 T1422 T1421 prep in,defect
R960 T1423 T1422 pobj BRCA2,in
R961 T1424 T1391 punct .,argue
R962 T1426 T1427 advmod First,measured
R963 T1428 T1427 punct ", ",measured
R964 T1429 T1427 prep in,measured
R965 T1430 T1431 det the,study
R966 T1431 T1429 pobj study,in
R967 T1432 T1431 amod same,study
R968 T1433 T1434 punct [,24
R969 T1434 T1431 parataxis 24,study
R970 T1435 T1434 punct ],24
R971 T1436 T1427 punct ", ",measured
R972 T1437 T1427 nsubjpass recombination,measured
R973 T1438 T1437 prep in,recombination
R974 T1439 T1440 det a,line
R975 T1440 T1438 pobj line,in
R976 T1441 T1440 compound mouse,line
R977 T1442 T1440 compound ES,line
R978 T1443 T1440 compound cell,line
R979 T1444 T1445 dep that,expresses
R980 T1445 T1440 relcl expresses,line
R981 T1446 T1447 advmod only,protein
R982 T1447 T1445 dobj protein,expresses
R983 T1448 T1447 amod truncated,protein
R984 T1449 T1447 compound BRCA2,protein
R985 T1450 T1427 auxpass was,measured
R986 T1451 T1427 punct .,measured
R987 T1453 T1454 det This,line
R988 T1454 T1455 nsubjpass line,found
R989 T1456 T1455 auxpass was,found
R990 T1457 T1458 aux to,have
R991 T1458 T1455 xcomp have,found
R992 T1459 T1460 amod lower,efficiency
R993 T1460 T1458 dobj efficiency,have
R994 T1461 T1460 compound recombination,efficiency
R995 T1462 T1460 prep than,efficiency
R996 T1463 T1464 amod isogenic,cells
R997 T1464 T1462 pobj cells,than
R998 T1465 T1464 acl expressing,cells
R999 T1466 T1467 amod full,length