| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T16908 |
0-3 |
DT |
denotes |
The |
| T16909 |
4-15 |
NN |
denotes |
integration |
| T16911 |
16-18 |
IN |
denotes |
of |
| T16912 |
19-30 |
JJ |
denotes |
traditional |
| T16913 |
31-39 |
NN |
denotes |
genetics |
| T16914 |
40-44 |
IN |
denotes |
with |
| T16915 |
45-51 |
NN |
denotes |
genome |
| T16917 |
51-52 |
HYPH |
denotes |
- |
| T16916 |
52-56 |
JJ |
denotes |
wide |
| T16919 |
57-67 |
NN |
denotes |
expression |
| T16918 |
68-76 |
NN |
denotes |
analysis |
| T16920 |
77-80 |
VBD |
denotes |
was |
| T16921 |
81-86 |
RB |
denotes |
first |
| T16910 |
87-95 |
VBN |
denotes |
proposed |
| T16922 |
96-98 |
IN |
denotes |
by |
| T16923 |
99-105 |
NNP |
denotes |
Jansen |
| T16924 |
106-109 |
CC |
denotes |
and |
| T16925 |
110-113 |
NNP |
denotes |
Nap |
| T16926 |
114-115 |
CD |
denotes |
4 |
| T16927 |
116-117 |
NN |
denotes |
y |
| T16928 |
118-121 |
RB |
denotes |
ago |
| T16929 |
122-123 |
-LRB- |
denotes |
[ |
| T16930 |
123-125 |
CD |
denotes |
32 |
| T16931 |
125-126 |
-RRB- |
denotes |
] |
| T16932 |
126-127 |
. |
denotes |
. |
| T16933 |
127-290 |
sentence |
denotes |
Advances in genomic technology and bioinformatic resources since then have vastly improved the applicability of these methods to the dissection of complex traits. |
| T16934 |
128-136 |
NNS |
denotes |
Advances |
| T16936 |
137-139 |
IN |
denotes |
in |
| T16937 |
140-147 |
JJ |
denotes |
genomic |
| T16938 |
148-158 |
NN |
denotes |
technology |
| T16939 |
159-162 |
CC |
denotes |
and |
| T16940 |
163-176 |
JJ |
denotes |
bioinformatic |
| T16941 |
177-186 |
NNS |
denotes |
resources |
| T16942 |
187-192 |
IN |
denotes |
since |
| T16943 |
193-197 |
RB |
denotes |
then |
| T16944 |
198-202 |
VBP |
denotes |
have |
| T16945 |
203-209 |
RB |
denotes |
vastly |
| T16935 |
210-218 |
VBN |
denotes |
improved |
| T16946 |
219-222 |
DT |
denotes |
the |
| T16947 |
223-236 |
NN |
denotes |
applicability |
| T16948 |
237-239 |
IN |
denotes |
of |
| T16949 |
240-245 |
DT |
denotes |
these |
| T16950 |
246-253 |
NNS |
denotes |
methods |
| T16951 |
254-256 |
IN |
denotes |
to |
| T16952 |
257-260 |
DT |
denotes |
the |
| T16953 |
261-271 |
NN |
denotes |
dissection |
| T16954 |
272-274 |
IN |
denotes |
of |
| T16955 |
275-282 |
JJ |
denotes |
complex |
| T16956 |
283-289 |
NNS |
denotes |
traits |
| T16957 |
289-290 |
. |
denotes |
. |
| T16958 |
290-466 |
sentence |
denotes |
Taking into account sex-specific effects will similarly improve the sensitivity to detect underlying genetic regulation, especially for phenotypes known to be affected by sex. |
| T16959 |
291-297 |
VBG |
denotes |
Taking |
| T16961 |
298-302 |
IN |
denotes |
into |
| T16962 |
303-310 |
NN |
denotes |
account |
| T16963 |
311-314 |
NN |
denotes |
sex |
| T16965 |
314-315 |
HYPH |
denotes |
- |
| T16964 |
315-323 |
JJ |
denotes |
specific |
| T16966 |
324-331 |
NNS |
denotes |
effects |
| T16967 |
332-336 |
MD |
denotes |
will |
| T16968 |
337-346 |
RB |
denotes |
similarly |
| T16960 |
347-354 |
VB |
denotes |
improve |
| T16969 |
355-358 |
DT |
denotes |
the |
| T16970 |
359-370 |
NN |
denotes |
sensitivity |
| T16971 |
371-373 |
TO |
denotes |
to |
| T16972 |
374-380 |
VB |
denotes |
detect |
| T16973 |
381-391 |
VBG |
denotes |
underlying |
| T16975 |
392-399 |
JJ |
denotes |
genetic |
| T16974 |
400-410 |
NN |
denotes |
regulation |
| T16976 |
410-412 |
, |
denotes |
, |
| T16977 |
412-422 |
RB |
denotes |
especially |
| T16978 |
423-426 |
IN |
denotes |
for |
| T16979 |
427-437 |
NNS |
denotes |
phenotypes |
| T16980 |
438-443 |
VBN |
denotes |
known |
| T16981 |
444-446 |
TO |
denotes |
to |
| T16983 |
447-449 |
VB |
denotes |
be |
| T16982 |
450-458 |
VBN |
denotes |
affected |
| T16984 |
459-461 |
IN |
denotes |
by |
| T16985 |
462-465 |
NN |
denotes |
sex |
| T16986 |
465-466 |
. |
denotes |
. |
| T16987 |
466-558 |
sentence |
denotes |
Furthermore, network analyses are increasingly being applied to complex phenotypes [11,33]. |
| T16988 |
467-478 |
RB |
denotes |
Furthermore |
| T16990 |
478-480 |
, |
denotes |
, |
| T16991 |
480-487 |
NN |
denotes |
network |
| T16992 |
488-496 |
NNS |
denotes |
analyses |
| T16993 |
497-500 |
VBP |
denotes |
are |
| T16994 |
501-513 |
RB |
denotes |
increasingly |
| T16995 |
514-519 |
VBG |
denotes |
being |
| T16989 |
520-527 |
VBN |
denotes |
applied |
| T16996 |
528-530 |
IN |
denotes |
to |
| T16997 |
531-538 |
JJ |
denotes |
complex |
| T16998 |
539-549 |
NNS |
denotes |
phenotypes |
| T16999 |
550-551 |
-LRB- |
denotes |
[ |
| T17001 |
551-553 |
CD |
denotes |
11 |
| T17002 |
553-554 |
, |
denotes |
, |
| T17000 |
554-556 |
CD |
denotes |
33 |
| T17003 |
556-557 |
-RRB- |
denotes |
] |
| T17004 |
557-558 |
. |
denotes |
. |
| T17005 |
558-895 |
sentence |
denotes |
Regardless of which variables are used in the construction of these networks, whether they measure gene expression or protein interactions, accounting for sex specificity, hormonal status, or construction of different networks for females and males would likely more accurately represent the complexity associated with these phenotypes. |
| T17006 |
559-569 |
RB |
denotes |
Regardless |
| T17008 |
570-572 |
IN |
denotes |
of |
| T17009 |
573-578 |
WDT |
denotes |
which |
| T17010 |
579-588 |
NNS |
denotes |
variables |
| T17012 |
589-592 |
VBP |
denotes |
are |
| T17011 |
593-597 |
VBN |
denotes |
used |
| T17013 |
598-600 |
IN |
denotes |
in |
| T17014 |
601-604 |
DT |
denotes |
the |
| T17015 |
605-617 |
NN |
denotes |
construction |
| T17016 |
618-620 |
IN |
denotes |
of |
| T17017 |
621-626 |
DT |
denotes |
these |
| T17018 |
627-635 |
NNS |
denotes |
networks |
| T17019 |
635-637 |
, |
denotes |
, |
| T17020 |
637-644 |
IN |
denotes |
whether |
| T17022 |
645-649 |
PRP |
denotes |
they |
| T17021 |
650-657 |
VBP |
denotes |
measure |
| T17023 |
658-662 |
NN |
denotes |
gene |
| T17024 |
663-673 |
NN |
denotes |
expression |
| T17025 |
674-676 |
CC |
denotes |
or |
| T17026 |
677-684 |
NN |
denotes |
protein |
| T17027 |
685-697 |
NNS |
denotes |
interactions |
| T17028 |
697-699 |
, |
denotes |
, |
| T17029 |
699-709 |
VBG |
denotes |
accounting |
| T17030 |
710-713 |
IN |
denotes |
for |
| T17031 |
714-717 |
NN |
denotes |
sex |
| T17032 |
718-729 |
NN |
denotes |
specificity |
| T17033 |
729-731 |
, |
denotes |
, |
| T17034 |
731-739 |
JJ |
denotes |
hormonal |
| T17035 |
740-746 |
NN |
denotes |
status |
| T17036 |
746-748 |
, |
denotes |
, |
| T17037 |
748-750 |
CC |
denotes |
or |
| T17038 |
751-763 |
NN |
denotes |
construction |
| T17039 |
764-766 |
IN |
denotes |
of |
| T17040 |
767-776 |
JJ |
denotes |
different |
| T17041 |
777-785 |
NNS |
denotes |
networks |
| T17042 |
786-789 |
IN |
denotes |
for |
| T17043 |
790-797 |
NNS |
denotes |
females |
| T17044 |
798-801 |
CC |
denotes |
and |
| T17045 |
802-807 |
NNS |
denotes |
males |
| T17046 |
808-813 |
MD |
denotes |
would |
| T17047 |
814-820 |
RB |
denotes |
likely |
| T17048 |
821-825 |
RBR |
denotes |
more |
| T17049 |
826-836 |
RB |
denotes |
accurately |
| T17007 |
837-846 |
VB |
denotes |
represent |
| T17050 |
847-850 |
DT |
denotes |
the |
| T17051 |
851-861 |
NN |
denotes |
complexity |
| T17052 |
862-872 |
VBN |
denotes |
associated |
| T17053 |
873-877 |
IN |
denotes |
with |
| T17054 |
878-883 |
DT |
denotes |
these |
| T17055 |
884-894 |
NNS |
denotes |
phenotypes |
| T17056 |
894-895 |
. |
denotes |
. |
| R5217 |
T16908 |
T16909 |
det |
The,integration |
| R5218 |
T16909 |
T16910 |
nsubjpass |
integration,proposed |
| R5219 |
T16911 |
T16909 |
prep |
of,integration |
| R5220 |
T16912 |
T16913 |
amod |
traditional,genetics |
| R5221 |
T16913 |
T16911 |
pobj |
genetics,of |
| R5222 |
T16914 |
T16909 |
prep |
with,integration |
| R5223 |
T16915 |
T16916 |
npadvmod |
genome,wide |
| R5224 |
T16916 |
T16918 |
amod |
wide,analysis |
| R5225 |
T16917 |
T16916 |
punct |
-,wide |
| R5226 |
T16918 |
T16914 |
pobj |
analysis,with |
| R5227 |
T16919 |
T16918 |
compound |
expression,analysis |
| R5228 |
T16920 |
T16910 |
auxpass |
was,proposed |
| R5229 |
T16921 |
T16910 |
advmod |
first,proposed |
| R5230 |
T16922 |
T16910 |
agent |
by,proposed |
| R5231 |
T16923 |
T16922 |
pobj |
Jansen,by |
| R5232 |
T16924 |
T16923 |
cc |
and,Jansen |
| R5233 |
T16925 |
T16923 |
conj |
Nap,Jansen |
| R5234 |
T16926 |
T16927 |
nummod |
4,y |
| R5235 |
T16927 |
T16928 |
npadvmod |
y,ago |
| R5236 |
T16928 |
T16910 |
advmod |
ago,proposed |
| R5237 |
T16929 |
T16930 |
punct |
[,32 |
| R5238 |
T16930 |
T16910 |
parataxis |
32,proposed |
| R5239 |
T16931 |
T16930 |
punct |
],32 |
| R5240 |
T16932 |
T16910 |
punct |
.,proposed |
| R5241 |
T16934 |
T16935 |
nsubj |
Advances,improved |
| R5242 |
T16936 |
T16934 |
prep |
in,Advances |
| R5243 |
T16937 |
T16938 |
amod |
genomic,technology |
| R5244 |
T16938 |
T16936 |
pobj |
technology,in |
| R5245 |
T16939 |
T16938 |
cc |
and,technology |
| R5246 |
T16940 |
T16941 |
amod |
bioinformatic,resources |
| R5247 |
T16941 |
T16938 |
conj |
resources,technology |
| R5248 |
T16942 |
T16935 |
prep |
since,improved |
| R5249 |
T16943 |
T16942 |
pcomp |
then,since |
| R5250 |
T16944 |
T16935 |
aux |
have,improved |
| R5251 |
T16945 |
T16935 |
advmod |
vastly,improved |
| R5252 |
T16946 |
T16947 |
det |
the,applicability |
| R5253 |
T16947 |
T16935 |
dobj |
applicability,improved |
| R5254 |
T16948 |
T16947 |
prep |
of,applicability |
| R5255 |
T16949 |
T16950 |
det |
these,methods |
| R5256 |
T16950 |
T16948 |
pobj |
methods,of |
| R5257 |
T16951 |
T16947 |
prep |
to,applicability |
| R5258 |
T16952 |
T16953 |
det |
the,dissection |
| R5259 |
T16953 |
T16951 |
pobj |
dissection,to |
| R5260 |
T16954 |
T16953 |
prep |
of,dissection |
| R5261 |
T16955 |
T16956 |
amod |
complex,traits |
| R5262 |
T16956 |
T16954 |
pobj |
traits,of |
| R5263 |
T16957 |
T16935 |
punct |
.,improved |
| R5264 |
T16959 |
T16960 |
csubj |
Taking,improve |
| R5265 |
T16961 |
T16959 |
prep |
into,Taking |
| R5266 |
T16962 |
T16961 |
pobj |
account,into |
| R5267 |
T16963 |
T16964 |
npadvmod |
sex,specific |
| R5268 |
T16964 |
T16966 |
amod |
specific,effects |
| R5269 |
T16965 |
T16964 |
punct |
-,specific |
| R5270 |
T16966 |
T16959 |
dobj |
effects,Taking |
| R5271 |
T16967 |
T16960 |
aux |
will,improve |
| R5272 |
T16968 |
T16960 |
advmod |
similarly,improve |
| R5273 |
T16969 |
T16970 |
det |
the,sensitivity |
| R5274 |
T16970 |
T16960 |
dobj |
sensitivity,improve |
| R5275 |
T16971 |
T16972 |
aux |
to,detect |
| R5276 |
T16972 |
T16970 |
acl |
detect,sensitivity |
| R5277 |
T16973 |
T16974 |
amod |
underlying,regulation |
| R5278 |
T16974 |
T16972 |
dobj |
regulation,detect |
| R5279 |
T16975 |
T16974 |
amod |
genetic,regulation |
| R5280 |
T16976 |
T16960 |
punct |
", ",improve |
| R5281 |
T16977 |
T16978 |
advmod |
especially,for |
| R5282 |
T16978 |
T16960 |
prep |
for,improve |
| R5283 |
T16979 |
T16978 |
pobj |
phenotypes,for |
| R5284 |
T16980 |
T16979 |
acl |
known,phenotypes |
| R5285 |
T16981 |
T16982 |
aux |
to,affected |
| R5286 |
T16982 |
T16980 |
xcomp |
affected,known |
| R5287 |
T16983 |
T16982 |
auxpass |
be,affected |
| R5288 |
T16984 |
T16982 |
agent |
by,affected |
| R5289 |
T16985 |
T16984 |
pobj |
sex,by |
| R5290 |
T16986 |
T16960 |
punct |
.,improve |
| R5291 |
T16988 |
T16989 |
advmod |
Furthermore,applied |
| R5292 |
T16990 |
T16989 |
punct |
", ",applied |
| R5293 |
T16991 |
T16992 |
compound |
network,analyses |
| R5294 |
T16992 |
T16989 |
nsubjpass |
analyses,applied |
| R5295 |
T16993 |
T16989 |
aux |
are,applied |
| R5296 |
T16994 |
T16989 |
advmod |
increasingly,applied |
| R5297 |
T16995 |
T16989 |
auxpass |
being,applied |
| R5298 |
T16996 |
T16989 |
prep |
to,applied |
| R5299 |
T16997 |
T16998 |
amod |
complex,phenotypes |
| R5300 |
T16998 |
T16996 |
pobj |
phenotypes,to |
| R5301 |
T16999 |
T17000 |
punct |
[,33 |
| R5302 |
T17000 |
T16989 |
parataxis |
33,applied |
| R5303 |
T17001 |
T17000 |
nummod |
11,33 |
| R5304 |
T17002 |
T17000 |
punct |
",",33 |
| R5305 |
T17003 |
T17000 |
punct |
],33 |
| R5306 |
T17004 |
T16989 |
punct |
.,applied |
| R5307 |
T17006 |
T17007 |
advmod |
Regardless,represent |
| R5308 |
T17008 |
T17006 |
prep |
of,Regardless |
| R5309 |
T17009 |
T17010 |
det |
which,variables |
| R5310 |
T17010 |
T17011 |
dep |
variables,used |
| R5311 |
T17011 |
T17008 |
pcomp |
used,of |
| R5312 |
T17012 |
T17011 |
auxpass |
are,used |
| R5313 |
T17013 |
T17011 |
prep |
in,used |
| R5314 |
T17014 |
T17015 |
det |
the,construction |
| R5315 |
T17015 |
T17013 |
pobj |
construction,in |
| R5316 |
T17016 |
T17015 |
prep |
of,construction |
| R5317 |
T17017 |
T17018 |
det |
these,networks |
| R5318 |
T17018 |
T17016 |
pobj |
networks,of |
| R5319 |
T17019 |
T17011 |
punct |
", ",used |
| R5320 |
T17020 |
T17021 |
mark |
whether,measure |
| R5321 |
T17021 |
T17011 |
advcl |
measure,used |
| R5322 |
T17022 |
T17021 |
nsubj |
they,measure |
| R5323 |
T17023 |
T17024 |
compound |
gene,expression |
| R5324 |
T17024 |
T17021 |
dobj |
expression,measure |
| R5325 |
T17025 |
T17024 |
cc |
or,expression |
| R5326 |
T17026 |
T17027 |
compound |
protein,interactions |
| R5327 |
T17027 |
T17024 |
conj |
interactions,expression |
| R5328 |
T17028 |
T17007 |
punct |
", ",represent |
| R5329 |
T17029 |
T17007 |
csubj |
accounting,represent |
| R5330 |
T17030 |
T17029 |
prep |
for,accounting |
| R5331 |
T17031 |
T17032 |
compound |
sex,specificity |
| R5332 |
T17032 |
T17030 |
pobj |
specificity,for |
| R5333 |
T17033 |
T17032 |
punct |
", ",specificity |
| R5334 |
T17034 |
T17035 |
amod |
hormonal,status |
| R5335 |
T17035 |
T17032 |
conj |
status,specificity |
| R5336 |
T17036 |
T17035 |
punct |
", ",status |
| R5337 |
T17037 |
T17035 |
cc |
or,status |
| R5338 |
T17038 |
T17035 |
conj |
construction,status |
| R5339 |
T17039 |
T17038 |
prep |
of,construction |
| R5340 |
T17040 |
T17041 |
amod |
different,networks |
| R5341 |
T17041 |
T17039 |
pobj |
networks,of |
| R5342 |
T17042 |
T17041 |
prep |
for,networks |
| R5343 |
T17043 |
T17042 |
pobj |
females,for |
| R5344 |
T17044 |
T17043 |
cc |
and,females |
| R5345 |
T17045 |
T17043 |
conj |
males,females |
| R5346 |
T17046 |
T17007 |
aux |
would,represent |
| R5347 |
T17047 |
T17007 |
advmod |
likely,represent |
| R5348 |
T17048 |
T17049 |
advmod |
more,accurately |
| R5349 |
T17049 |
T17007 |
advmod |
accurately,represent |
| R5350 |
T17050 |
T17051 |
det |
the,complexity |
| R5351 |
T17051 |
T17007 |
dobj |
complexity,represent |
| R5352 |
T17052 |
T17051 |
acl |
associated,complexity |
| R5353 |
T17053 |
T17052 |
prep |
with,associated |
| R5354 |
T17054 |
T17055 |
det |
these,phenotypes |
| R5355 |
T17055 |
T17053 |
pobj |
phenotypes,with |
| R5356 |
T17056 |
T17007 |
punct |
.,represent |