Id |
Subject |
Object |
Predicate |
Lexical cue |
T15871 |
0-4 |
RB |
denotes |
Thus |
T15872 |
5-8 |
RB |
denotes |
far |
T15874 |
8-10 |
, |
denotes |
, |
T15875 |
10-17 |
NNS |
denotes |
studies |
T15876 |
18-22 |
WDT |
denotes |
that |
T15878 |
23-27 |
VBP |
denotes |
have |
T15877 |
28-36 |
VBN |
denotes |
examined |
T15879 |
37-40 |
DT |
denotes |
the |
T15881 |
41-42 |
`` |
denotes |
“ |
T15880 |
42-50 |
NN |
denotes |
genetics |
T15882 |
51-53 |
IN |
denotes |
of |
T15883 |
54-58 |
NN |
denotes |
gene |
T15884 |
59-69 |
NN |
denotes |
expression |
T15885 |
69-70 |
'' |
denotes |
” |
T15873 |
71-74 |
VBP |
denotes |
are |
T15886 |
75-77 |
IN |
denotes |
in |
T15887 |
78-82 |
JJ |
denotes |
good |
T15888 |
83-92 |
NN |
denotes |
agreement |
T15889 |
93-102 |
VBG |
denotes |
regarding |
T15890 |
103-106 |
DT |
denotes |
the |
T15892 |
107-116 |
VBN |
denotes |
increased |
T15891 |
117-122 |
NN |
denotes |
power |
T15893 |
123-125 |
TO |
denotes |
to |
T15894 |
126-132 |
VB |
denotes |
detect |
T15895 |
133-136 |
NN |
denotes |
cis |
T15897 |
136-137 |
HYPH |
denotes |
- |
T15896 |
137-142 |
NNS |
denotes |
eQTLs |
T15898 |
143-151 |
JJ |
denotes |
relative |
T15899 |
152-154 |
IN |
denotes |
to |
T15900 |
155-160 |
NN |
denotes |
trans |
T15901 |
161-162 |
-LRB- |
denotes |
[ |
T15903 |
162-163 |
CD |
denotes |
5 |
T15904 |
163-164 |
, |
denotes |
, |
T15905 |
164-165 |
CD |
denotes |
9 |
T15906 |
165-166 |
, |
denotes |
, |
T15907 |
166-168 |
CD |
denotes |
15 |
T15908 |
168-169 |
, |
denotes |
, |
T15909 |
169-171 |
CD |
denotes |
16 |
T15910 |
171-172 |
, |
denotes |
, |
T15902 |
172-174 |
CD |
denotes |
31 |
T15911 |
174-175 |
-RRB- |
denotes |
] |
T15912 |
175-176 |
. |
denotes |
. |
T15913 |
176-330 |
sentence |
denotes |
It is unclear at this time, however, what exactly is the significance of trans-eQTLs and the nature of the underlying polymorphisms associated with them. |
T15914 |
177-179 |
PRP |
denotes |
It |
T15915 |
180-182 |
VBZ |
denotes |
is |
T15916 |
183-190 |
JJ |
denotes |
unclear |
T15917 |
191-193 |
IN |
denotes |
at |
T15918 |
194-198 |
DT |
denotes |
this |
T15919 |
199-203 |
NN |
denotes |
time |
T15920 |
203-205 |
, |
denotes |
, |
T15921 |
205-212 |
RB |
denotes |
however |
T15922 |
212-214 |
, |
denotes |
, |
T15923 |
214-218 |
WP |
denotes |
what |
T15925 |
219-226 |
RB |
denotes |
exactly |
T15924 |
227-229 |
VBZ |
denotes |
is |
T15926 |
230-233 |
DT |
denotes |
the |
T15927 |
234-246 |
NN |
denotes |
significance |
T15928 |
247-249 |
IN |
denotes |
of |
T15929 |
250-255 |
NN |
denotes |
trans |
T15931 |
255-256 |
HYPH |
denotes |
- |
T15930 |
256-261 |
NNS |
denotes |
eQTLs |
T15932 |
262-265 |
CC |
denotes |
and |
T15933 |
266-269 |
DT |
denotes |
the |
T15934 |
270-276 |
NN |
denotes |
nature |
T15935 |
277-279 |
IN |
denotes |
of |
T15936 |
280-283 |
DT |
denotes |
the |
T15938 |
284-294 |
VBG |
denotes |
underlying |
T15937 |
295-308 |
NNS |
denotes |
polymorphisms |
T15939 |
309-319 |
VBN |
denotes |
associated |
T15940 |
320-324 |
IN |
denotes |
with |
T15941 |
325-329 |
PRP |
denotes |
them |
T15942 |
329-330 |
. |
denotes |
. |
T15943 |
330-439 |
sentence |
denotes |
Furthermore, the eQTL hotspots reported in this and previous studies [5,9,10] largely represent trans-eQTLs. |
T15944 |
331-342 |
RB |
denotes |
Furthermore |
T15946 |
342-344 |
, |
denotes |
, |
T15947 |
344-347 |
DT |
denotes |
the |
T15949 |
348-352 |
NN |
denotes |
eQTL |
T15948 |
353-361 |
NNS |
denotes |
hotspots |
T15950 |
362-370 |
VBN |
denotes |
reported |
T15951 |
371-373 |
IN |
denotes |
in |
T15952 |
374-378 |
DT |
denotes |
this |
T15954 |
379-382 |
CC |
denotes |
and |
T15953 |
383-391 |
JJ |
denotes |
previous |
T15955 |
392-399 |
NNS |
denotes |
studies |
T15956 |
400-401 |
-LRB- |
denotes |
[ |
T15958 |
401-402 |
CD |
denotes |
5 |
T15959 |
402-403 |
, |
denotes |
, |
T15960 |
403-404 |
CD |
denotes |
9 |
T15961 |
404-405 |
, |
denotes |
, |
T15957 |
405-407 |
CD |
denotes |
10 |
T15962 |
407-408 |
-RRB- |
denotes |
] |
T15963 |
409-416 |
RB |
denotes |
largely |
T15945 |
417-426 |
VBP |
denotes |
represent |
T15964 |
427-432 |
NN |
denotes |
trans |
T15966 |
432-433 |
HYPH |
denotes |
- |
T15965 |
433-438 |
NNS |
denotes |
eQTLs |
T15967 |
438-439 |
. |
denotes |
. |
T15968 |
439-513 |
sentence |
denotes |
This localization suggests some functional significance to these regions. |
T15969 |
440-444 |
DT |
denotes |
This |
T15970 |
445-457 |
NN |
denotes |
localization |
T15971 |
458-466 |
VBZ |
denotes |
suggests |
T15972 |
467-471 |
DT |
denotes |
some |
T15974 |
472-482 |
JJ |
denotes |
functional |
T15973 |
483-495 |
NN |
denotes |
significance |
T15975 |
496-498 |
IN |
denotes |
to |
T15976 |
499-504 |
DT |
denotes |
these |
T15977 |
505-512 |
NNS |
denotes |
regions |
T15978 |
512-513 |
. |
denotes |
. |
T15979 |
513-645 |
sentence |
denotes |
Of the 4,613 genes correlated with gonadal fat mass, 1,130 generate 1,478 significant eQTLs, of which 1,023 (69%) are trans-acting. |
T15980 |
514-516 |
IN |
denotes |
Of |
T15982 |
517-520 |
DT |
denotes |
the |
T15984 |
521-526 |
CD |
denotes |
4,613 |
T15983 |
527-532 |
NNS |
denotes |
genes |
T15985 |
533-543 |
VBN |
denotes |
correlated |
T15986 |
544-548 |
IN |
denotes |
with |
T15987 |
549-556 |
JJ |
denotes |
gonadal |
T15989 |
557-560 |
NN |
denotes |
fat |
T15988 |
561-565 |
NN |
denotes |
mass |
T15990 |
565-567 |
, |
denotes |
, |
T15991 |
567-572 |
CD |
denotes |
1,130 |
T15981 |
573-581 |
VBP |
denotes |
generate |
T15992 |
582-587 |
CD |
denotes |
1,478 |
T15994 |
588-599 |
JJ |
denotes |
significant |
T15993 |
600-605 |
NNS |
denotes |
eQTLs |
T15995 |
605-607 |
, |
denotes |
, |
T15996 |
607-609 |
IN |
denotes |
of |
T15998 |
610-615 |
WDT |
denotes |
which |
T15999 |
616-621 |
CD |
denotes |
1,023 |
T16000 |
622-623 |
-LRB- |
denotes |
( |
T16002 |
623-625 |
CD |
denotes |
69 |
T16001 |
625-626 |
NN |
denotes |
% |
T16003 |
626-627 |
-RRB- |
denotes |
) |
T15997 |
628-631 |
VBP |
denotes |
are |
T16004 |
632-637 |
NN |
denotes |
trans |
T16006 |
637-638 |
HYPH |
denotes |
- |
T16005 |
638-644 |
VBG |
denotes |
acting |
T16007 |
644-645 |
. |
denotes |
. |
T16008 |
645-714 |
sentence |
denotes |
These eQTLs are significantly enriched at one locus (Chromosome 19). |
T16009 |
646-651 |
DT |
denotes |
These |
T16010 |
652-657 |
NNS |
denotes |
eQTLs |
T16012 |
658-661 |
VBP |
denotes |
are |
T16013 |
662-675 |
RB |
denotes |
significantly |
T16011 |
676-684 |
VBN |
denotes |
enriched |
T16014 |
685-687 |
IN |
denotes |
at |
T16015 |
688-691 |
CD |
denotes |
one |
T16016 |
692-697 |
NN |
denotes |
locus |
T16017 |
698-699 |
-LRB- |
denotes |
( |
T16018 |
699-709 |
NN |
denotes |
Chromosome |
T16019 |
710-712 |
CD |
denotes |
19 |
T16020 |
712-713 |
-RRB- |
denotes |
) |
T16021 |
713-714 |
. |
denotes |
. |
T16022 |
714-818 |
sentence |
denotes |
Interestingly, this hotspot was coincident with a cQTL associated with fat mass reported in this study. |
T16023 |
715-728 |
RB |
denotes |
Interestingly |
T16025 |
728-730 |
, |
denotes |
, |
T16026 |
730-734 |
DT |
denotes |
this |
T16027 |
735-742 |
NN |
denotes |
hotspot |
T16024 |
743-746 |
VBD |
denotes |
was |
T16028 |
747-757 |
JJ |
denotes |
coincident |
T16029 |
758-762 |
IN |
denotes |
with |
T16030 |
763-764 |
DT |
denotes |
a |
T16031 |
765-769 |
NN |
denotes |
cQTL |
T16032 |
770-780 |
VBN |
denotes |
associated |
T16033 |
781-785 |
IN |
denotes |
with |
T16034 |
786-789 |
NN |
denotes |
fat |
T16035 |
790-794 |
NN |
denotes |
mass |
T16036 |
795-803 |
VBN |
denotes |
reported |
T16037 |
804-806 |
IN |
denotes |
in |
T16038 |
807-811 |
DT |
denotes |
this |
T16039 |
812-817 |
NN |
denotes |
study |
T16040 |
817-818 |
. |
denotes |
. |
T16041 |
818-1123 |
sentence |
denotes |
Since these transcripts represent those significantly correlated with gonadal fat mass, the localization of their eQTLs to these regions strongly supports the notion that the genes with trans-eQTLs represent downstream targets of candidate regulatory genes located at the position of significant linkage. |
T16042 |
819-824 |
IN |
denotes |
Since |
T16044 |
825-830 |
DT |
denotes |
these |
T16045 |
831-842 |
NNS |
denotes |
transcripts |
T16043 |
843-852 |
VBP |
denotes |
represent |
T16047 |
853-858 |
DT |
denotes |
those |
T16048 |
859-872 |
RB |
denotes |
significantly |
T16049 |
873-883 |
VBN |
denotes |
correlated |
T16050 |
884-888 |
IN |
denotes |
with |
T16051 |
889-896 |
JJ |
denotes |
gonadal |
T16053 |
897-900 |
NN |
denotes |
fat |
T16052 |
901-905 |
NN |
denotes |
mass |
T16054 |
905-907 |
, |
denotes |
, |
T16055 |
907-910 |
DT |
denotes |
the |
T16056 |
911-923 |
NN |
denotes |
localization |
T16057 |
924-926 |
IN |
denotes |
of |
T16058 |
927-932 |
PRP$ |
denotes |
their |
T16059 |
933-938 |
NNS |
denotes |
eQTLs |
T16060 |
939-941 |
IN |
denotes |
to |
T16061 |
942-947 |
DT |
denotes |
these |
T16062 |
948-955 |
NNS |
denotes |
regions |
T16063 |
956-964 |
RB |
denotes |
strongly |
T16046 |
965-973 |
VBZ |
denotes |
supports |
T16064 |
974-977 |
DT |
denotes |
the |
T16065 |
978-984 |
NN |
denotes |
notion |
T16066 |
985-989 |
IN |
denotes |
that |
T16068 |
990-993 |
DT |
denotes |
the |
T16069 |
994-999 |
NNS |
denotes |
genes |
T16070 |
1000-1004 |
IN |
denotes |
with |
T16071 |
1005-1010 |
NN |
denotes |
trans |
T16073 |
1010-1011 |
HYPH |
denotes |
- |
T16072 |
1011-1016 |
NNS |
denotes |
eQTLs |
T16067 |
1017-1026 |
VB |
denotes |
represent |
T16074 |
1027-1037 |
JJ |
denotes |
downstream |
T16075 |
1038-1045 |
NNS |
denotes |
targets |
T16076 |
1046-1048 |
IN |
denotes |
of |
T16077 |
1049-1058 |
NN |
denotes |
candidate |
T16079 |
1059-1069 |
JJ |
denotes |
regulatory |
T16078 |
1070-1075 |
NNS |
denotes |
genes |
T16080 |
1076-1083 |
VBN |
denotes |
located |
T16081 |
1084-1086 |
IN |
denotes |
at |
T16082 |
1087-1090 |
DT |
denotes |
the |
T16083 |
1091-1099 |
NN |
denotes |
position |
T16084 |
1100-1102 |
IN |
denotes |
of |
T16085 |
1103-1114 |
JJ |
denotes |
significant |
T16086 |
1115-1122 |
NN |
denotes |
linkage |
T16087 |
1122-1123 |
. |
denotes |
. |
T16088 |
1123-1309 |
sentence |
denotes |
This means that the genes may be causal but downstream of the gene responsible for the cQTLs, or they may be reacting to the increased gonadal fat mass and associated metabolic changes. |
T16089 |
1124-1128 |
DT |
denotes |
This |
T16090 |
1129-1134 |
VBZ |
denotes |
means |
T16091 |
1135-1139 |
IN |
denotes |
that |
T16093 |
1140-1143 |
DT |
denotes |
the |
T16094 |
1144-1149 |
NNS |
denotes |
genes |
T16095 |
1150-1153 |
MD |
denotes |
may |
T16092 |
1154-1156 |
VB |
denotes |
be |
T16096 |
1157-1163 |
JJ |
denotes |
causal |
T16097 |
1164-1167 |
CC |
denotes |
but |
T16098 |
1168-1178 |
RB |
denotes |
downstream |
T16099 |
1179-1181 |
IN |
denotes |
of |
T16100 |
1182-1185 |
DT |
denotes |
the |
T16101 |
1186-1190 |
NN |
denotes |
gene |
T16102 |
1191-1202 |
JJ |
denotes |
responsible |
T16103 |
1203-1206 |
IN |
denotes |
for |
T16104 |
1207-1210 |
DT |
denotes |
the |
T16105 |
1211-1216 |
NNS |
denotes |
cQTLs |
T16106 |
1216-1218 |
, |
denotes |
, |
T16107 |
1218-1220 |
CC |
denotes |
or |
T16108 |
1221-1225 |
PRP |
denotes |
they |
T16110 |
1226-1229 |
MD |
denotes |
may |
T16111 |
1230-1232 |
VB |
denotes |
be |
T16109 |
1233-1241 |
VBG |
denotes |
reacting |
T16112 |
1242-1244 |
IN |
denotes |
to |
T16113 |
1245-1248 |
DT |
denotes |
the |
T16115 |
1249-1258 |
VBN |
denotes |
increased |
T16116 |
1259-1266 |
JJ |
denotes |
gonadal |
T16117 |
1267-1270 |
NN |
denotes |
fat |
T16114 |
1271-1275 |
NN |
denotes |
mass |
T16118 |
1276-1279 |
CC |
denotes |
and |
T16119 |
1280-1290 |
VBN |
denotes |
associated |
T16121 |
1291-1300 |
JJ |
denotes |
metabolic |
T16120 |
1301-1308 |
NNS |
denotes |
changes |
T16122 |
1308-1309 |
. |
denotes |
. |
T16123 |
1309-1514 |
sentence |
denotes |
These data also suggest that identifying such loci that show overrepresentation of highly correlated genes is a means to identify which of the trait cQTLs are more likely controlled by the tissue arrayed. |
T16124 |
1310-1315 |
DT |
denotes |
These |
T16125 |
1316-1320 |
NNS |
denotes |
data |
T16127 |
1321-1325 |
RB |
denotes |
also |
T16126 |
1326-1333 |
VBP |
denotes |
suggest |
T16128 |
1334-1338 |
IN |
denotes |
that |
T16130 |
1339-1350 |
VBG |
denotes |
identifying |
T16131 |
1351-1355 |
JJ |
denotes |
such |
T16132 |
1356-1360 |
NNS |
denotes |
loci |
T16133 |
1361-1365 |
WDT |
denotes |
that |
T16134 |
1366-1370 |
VBP |
denotes |
show |
T16135 |
1371-1389 |
NN |
denotes |
overrepresentation |
T16136 |
1390-1392 |
IN |
denotes |
of |
T16137 |
1393-1399 |
RB |
denotes |
highly |
T16138 |
1400-1410 |
VBN |
denotes |
correlated |
T16139 |
1411-1416 |
NNS |
denotes |
genes |
T16129 |
1417-1419 |
VBZ |
denotes |
is |
T16140 |
1420-1421 |
DT |
denotes |
a |
T16141 |
1422-1427 |
NN |
denotes |
means |
T16142 |
1428-1430 |
TO |
denotes |
to |
T16143 |
1431-1439 |
VB |
denotes |
identify |
T16144 |
1440-1445 |
WDT |
denotes |
which |
T16146 |
1446-1448 |
IN |
denotes |
of |
T16147 |
1449-1452 |
DT |
denotes |
the |
T16149 |
1453-1458 |
NN |
denotes |
trait |
T16148 |
1459-1464 |
NNS |
denotes |
cQTLs |
T16150 |
1465-1468 |
VBP |
denotes |
are |
T16151 |
1469-1473 |
RBR |
denotes |
more |
T16152 |
1474-1480 |
RB |
denotes |
likely |
T16145 |
1481-1491 |
VBN |
denotes |
controlled |
T16153 |
1492-1494 |
IN |
denotes |
by |
T16154 |
1495-1498 |
DT |
denotes |
the |
T16155 |
1499-1505 |
NN |
denotes |
tissue |
T16156 |
1506-1513 |
VBN |
denotes |
arrayed |
T16157 |
1513-1514 |
. |
denotes |
. |
T16158 |
1514-1627 |
sentence |
denotes |
As expected, the Chromosome 19 locus was enriched for trans-eQTLs with substantially greater effects in females. |
T16159 |
1515-1517 |
IN |
denotes |
As |
T16160 |
1518-1526 |
VBN |
denotes |
expected |
T16162 |
1526-1528 |
, |
denotes |
, |
T16163 |
1528-1531 |
DT |
denotes |
the |
T16165 |
1532-1542 |
NN |
denotes |
Chromosome |
T16166 |
1543-1545 |
CD |
denotes |
19 |
T16164 |
1546-1551 |
NN |
denotes |
locus |
T16161 |
1552-1555 |
VBD |
denotes |
was |
T16167 |
1556-1564 |
JJ |
denotes |
enriched |
T16168 |
1565-1568 |
IN |
denotes |
for |
T16169 |
1569-1574 |
NN |
denotes |
trans |
T16171 |
1574-1575 |
HYPH |
denotes |
- |
T16170 |
1575-1580 |
NNS |
denotes |
eQTLs |
T16172 |
1581-1585 |
IN |
denotes |
with |
T16173 |
1586-1599 |
RB |
denotes |
substantially |
T16174 |
1600-1607 |
JJR |
denotes |
greater |
T16175 |
1608-1615 |
NNS |
denotes |
effects |
T16176 |
1616-1618 |
IN |
denotes |
in |
T16177 |
1619-1626 |
NNS |
denotes |
females |
T16178 |
1626-1627 |
. |
denotes |
. |
T16179 |
1627-1718 |
sentence |
denotes |
Functional and promoter analysis of genes with a common trans-eQTL may prove enlightening. |
T16180 |
1628-1638 |
JJ |
denotes |
Functional |
T16182 |
1639-1642 |
CC |
denotes |
and |
T16183 |
1643-1651 |
NN |
denotes |
promoter |
T16181 |
1652-1660 |
NN |
denotes |
analysis |
T16185 |
1661-1663 |
IN |
denotes |
of |
T16186 |
1664-1669 |
NNS |
denotes |
genes |
T16187 |
1670-1674 |
IN |
denotes |
with |
T16188 |
1675-1676 |
DT |
denotes |
a |
T16190 |
1677-1683 |
JJ |
denotes |
common |
T16191 |
1684-1689 |
NN |
denotes |
trans |
T16192 |
1689-1690 |
HYPH |
denotes |
- |
T16189 |
1690-1694 |
NN |
denotes |
eQTL |
T16193 |
1695-1698 |
MD |
denotes |
may |
T16184 |
1699-1704 |
VB |
denotes |
prove |
T16194 |
1705-1717 |
JJ |
denotes |
enlightening |
T16195 |
1717-1718 |
. |
denotes |
. |
T16196 |
1718-1878 |
sentence |
denotes |
Furthermore, gene expression network construction and analysis may be improved by the incorporation of experimentally demonstrated cis versus trans regulation. |
T16197 |
1719-1730 |
RB |
denotes |
Furthermore |
T16199 |
1730-1732 |
, |
denotes |
, |
T16200 |
1732-1736 |
NN |
denotes |
gene |
T16201 |
1737-1747 |
NN |
denotes |
expression |
T16203 |
1748-1755 |
NN |
denotes |
network |
T16202 |
1756-1768 |
NN |
denotes |
construction |
T16204 |
1769-1772 |
CC |
denotes |
and |
T16205 |
1773-1781 |
NN |
denotes |
analysis |
T16206 |
1782-1785 |
MD |
denotes |
may |
T16207 |
1786-1788 |
VB |
denotes |
be |
T16198 |
1789-1797 |
VBN |
denotes |
improved |
T16208 |
1798-1800 |
IN |
denotes |
by |
T16209 |
1801-1804 |
DT |
denotes |
the |
T16210 |
1805-1818 |
NN |
denotes |
incorporation |
T16211 |
1819-1821 |
IN |
denotes |
of |
T16212 |
1822-1836 |
RB |
denotes |
experimentally |
T16213 |
1837-1849 |
VBN |
denotes |
demonstrated |
T16215 |
1850-1853 |
NN |
denotes |
cis |
T16217 |
1854-1860 |
IN |
denotes |
versus |
T16216 |
1861-1866 |
NN |
denotes |
trans |
T16214 |
1867-1877 |
NN |
denotes |
regulation |
T16218 |
1877-1878 |
. |
denotes |
. |
R4894 |
T15871 |
T15872 |
advmod |
Thus,far |
R4895 |
T15872 |
T15873 |
advmod |
far,are |
R4896 |
T15874 |
T15873 |
punct |
", ",are |
R4897 |
T15875 |
T15873 |
nsubj |
studies,are |
R4898 |
T15876 |
T15877 |
dep |
that,examined |
R4899 |
T15877 |
T15875 |
relcl |
examined,studies |
R4900 |
T15878 |
T15877 |
aux |
have,examined |
R4901 |
T15879 |
T15880 |
det |
the,genetics |
R4902 |
T15880 |
T15877 |
dobj |
genetics,examined |
R4903 |
T15881 |
T15880 |
punct |
“,genetics |
R4904 |
T15882 |
T15880 |
prep |
of,genetics |
R4905 |
T15883 |
T15884 |
compound |
gene,expression |
R4906 |
T15884 |
T15882 |
pobj |
expression,of |
R4907 |
T15885 |
T15873 |
punct |
”,are |
R4908 |
T15886 |
T15873 |
prep |
in,are |
R4909 |
T15887 |
T15888 |
amod |
good,agreement |
R4910 |
T15888 |
T15886 |
pobj |
agreement,in |
R4911 |
T15889 |
T15888 |
prep |
regarding,agreement |
R4912 |
T15890 |
T15891 |
det |
the,power |
R4913 |
T15891 |
T15889 |
pobj |
power,regarding |
R4914 |
T15892 |
T15891 |
amod |
increased,power |
R4915 |
T15893 |
T15894 |
aux |
to,detect |
R4916 |
T15894 |
T15891 |
acl |
detect,power |
R4917 |
T15895 |
T15896 |
compound |
cis,eQTLs |
R4918 |
T15896 |
T15894 |
dobj |
eQTLs,detect |
R4919 |
T15897 |
T15896 |
punct |
-,eQTLs |
R4920 |
T15898 |
T15894 |
advcl |
relative,detect |
R4921 |
T15899 |
T15898 |
prep |
to,relative |
R4922 |
T15900 |
T15899 |
pobj |
trans,to |
R4923 |
T15901 |
T15902 |
punct |
[,31 |
R4924 |
T15902 |
T15873 |
parataxis |
31,are |
R4925 |
T15903 |
T15902 |
nummod |
5,31 |
R4926 |
T15904 |
T15902 |
punct |
",",31 |
R4927 |
T15905 |
T15902 |
nummod |
9,31 |
R4928 |
T15906 |
T15902 |
punct |
",",31 |
R4929 |
T15907 |
T15902 |
nummod |
15,31 |
R4930 |
T15908 |
T15902 |
punct |
",",31 |
R4931 |
T15909 |
T15902 |
nummod |
16,31 |
R4932 |
T15910 |
T15902 |
punct |
",",31 |
R4933 |
T15911 |
T15902 |
punct |
],31 |
R4934 |
T15912 |
T15873 |
punct |
.,are |
R4935 |
T15914 |
T15915 |
nsubj |
It,is |
R4936 |
T15916 |
T15915 |
acomp |
unclear,is |
R4937 |
T15917 |
T15915 |
prep |
at,is |
R4938 |
T15918 |
T15919 |
det |
this,time |
R4939 |
T15919 |
T15917 |
pobj |
time,at |
R4940 |
T15920 |
T15915 |
punct |
", ",is |
R4941 |
T15921 |
T15915 |
advmod |
however,is |
R4942 |
T15922 |
T15915 |
punct |
", ",is |
R4943 |
T15923 |
T15924 |
dep |
what,is |
R4944 |
T15924 |
T15915 |
ccomp |
is,is |
R4945 |
T15925 |
T15923 |
advmod |
exactly,what |
R4946 |
T15926 |
T15927 |
det |
the,significance |
R4947 |
T15927 |
T15924 |
attr |
significance,is |
R4948 |
T15928 |
T15927 |
prep |
of,significance |
R4949 |
T15929 |
T15930 |
compound |
trans,eQTLs |
R4950 |
T15930 |
T15928 |
pobj |
eQTLs,of |
R4951 |
T15931 |
T15930 |
punct |
-,eQTLs |
R4952 |
T15932 |
T15927 |
cc |
and,significance |
R4953 |
T15933 |
T15934 |
det |
the,nature |
R4954 |
T15934 |
T15927 |
conj |
nature,significance |
R4955 |
T15935 |
T15934 |
prep |
of,nature |
R4956 |
T15936 |
T15937 |
det |
the,polymorphisms |
R4957 |
T15937 |
T15935 |
pobj |
polymorphisms,of |
R4958 |
T15938 |
T15937 |
amod |
underlying,polymorphisms |
R4959 |
T15939 |
T15937 |
acl |
associated,polymorphisms |
R4960 |
T15940 |
T15939 |
prep |
with,associated |
R4961 |
T15941 |
T15940 |
pobj |
them,with |
R4962 |
T15942 |
T15915 |
punct |
.,is |
R4963 |
T15944 |
T15945 |
advmod |
Furthermore,represent |
R4964 |
T15946 |
T15945 |
punct |
", ",represent |
R4965 |
T15947 |
T15948 |
det |
the,hotspots |
R4966 |
T15948 |
T15945 |
nsubj |
hotspots,represent |
R4967 |
T15949 |
T15948 |
compound |
eQTL,hotspots |
R4968 |
T15950 |
T15948 |
acl |
reported,hotspots |
R4969 |
T15951 |
T15950 |
prep |
in,reported |
R4970 |
T15952 |
T15953 |
advmod |
this,previous |
R4971 |
T15953 |
T15955 |
amod |
previous,studies |
R4972 |
T15954 |
T15953 |
cc |
and,previous |
R4973 |
T15955 |
T15951 |
pobj |
studies,in |
R4974 |
T15956 |
T15957 |
punct |
[,10 |
R4975 |
T15957 |
T15948 |
parataxis |
10,hotspots |
R4976 |
T15958 |
T15957 |
nummod |
5,10 |
R4977 |
T15959 |
T15957 |
punct |
",",10 |
R4978 |
T15960 |
T15957 |
nummod |
9,10 |
R4979 |
T15961 |
T15957 |
punct |
",",10 |
R4980 |
T15962 |
T15957 |
punct |
],10 |
R4981 |
T15963 |
T15945 |
advmod |
largely,represent |
R4982 |
T15964 |
T15965 |
compound |
trans,eQTLs |
R4983 |
T15965 |
T15945 |
dobj |
eQTLs,represent |
R4984 |
T15966 |
T15965 |
punct |
-,eQTLs |
R4985 |
T15967 |
T15945 |
punct |
.,represent |
R4986 |
T15969 |
T15970 |
det |
This,localization |
R4987 |
T15970 |
T15971 |
nsubj |
localization,suggests |
R4988 |
T15972 |
T15973 |
det |
some,significance |
R4989 |
T15973 |
T15971 |
dobj |
significance,suggests |
R4990 |
T15974 |
T15973 |
amod |
functional,significance |
R4991 |
T15975 |
T15973 |
prep |
to,significance |
R4992 |
T15976 |
T15977 |
det |
these,regions |
R4993 |
T15977 |
T15975 |
pobj |
regions,to |
R4994 |
T15978 |
T15971 |
punct |
.,suggests |
R4995 |
T15980 |
T15981 |
prep |
Of,generate |
R4996 |
T15982 |
T15983 |
det |
the,genes |
R4997 |
T15983 |
T15980 |
pobj |
genes,Of |
R4998 |
T15984 |
T15983 |
nummod |
"4,613",genes |
R4999 |
T15985 |
T15983 |
acl |
correlated,genes |
R5000 |
T15986 |
T15985 |
prep |
with,correlated |
R5001 |
T15987 |
T15988 |
amod |
gonadal,mass |
R5002 |
T15988 |
T15986 |
pobj |
mass,with |
R5003 |
T15989 |
T15988 |
compound |
fat,mass |
R5004 |
T15990 |
T15981 |
punct |
", ",generate |
R5005 |
T15991 |
T15981 |
nsubj |
"1,130",generate |
R5006 |
T15992 |
T15993 |
nummod |
"1,478",eQTLs |
R5007 |
T15993 |
T15981 |
dobj |
eQTLs,generate |
R5008 |
T15994 |
T15993 |
amod |
significant,eQTLs |
R5009 |
T15995 |
T15993 |
punct |
", ",eQTLs |
R5010 |
T15996 |
T15997 |
prep |
of,are |
R5011 |
T15997 |
T15993 |
relcl |
are,eQTLs |
R5012 |
T15998 |
T15996 |
pobj |
which,of |
R5013 |
T15999 |
T15997 |
nsubj |
"1,023",are |
R5014 |
T16000 |
T16001 |
punct |
(,% |
R5015 |
T16001 |
T15999 |
parataxis |
%,"1,023" |
R5016 |
T16002 |
T16001 |
nummod |
69,% |
R5017 |
T16003 |
T16001 |
punct |
),% |
R5018 |
T16004 |
T16005 |
npadvmod |
trans,acting |
R5019 |
T16005 |
T15997 |
acomp |
acting,are |
R5020 |
T16006 |
T16005 |
punct |
-,acting |
R5021 |
T16007 |
T15981 |
punct |
.,generate |
R5022 |
T16009 |
T16010 |
det |
These,eQTLs |
R5023 |
T16010 |
T16011 |
nsubjpass |
eQTLs,enriched |
R5024 |
T16012 |
T16011 |
auxpass |
are,enriched |
R5025 |
T16013 |
T16011 |
advmod |
significantly,enriched |
R5026 |
T16014 |
T16011 |
prep |
at,enriched |
R5027 |
T16015 |
T16016 |
nummod |
one,locus |
R5028 |
T16016 |
T16014 |
pobj |
locus,at |
R5029 |
T16017 |
T16018 |
punct |
(,Chromosome |
R5030 |
T16018 |
T16016 |
parataxis |
Chromosome,locus |
R5031 |
T16019 |
T16018 |
nummod |
19,Chromosome |
R5032 |
T16020 |
T16018 |
punct |
),Chromosome |
R5033 |
T16021 |
T16011 |
punct |
.,enriched |
R5034 |
T16023 |
T16024 |
advmod |
Interestingly,was |
R5035 |
T16025 |
T16024 |
punct |
", ",was |
R5036 |
T16026 |
T16027 |
det |
this,hotspot |
R5037 |
T16027 |
T16024 |
nsubj |
hotspot,was |
R5038 |
T16028 |
T16024 |
acomp |
coincident,was |
R5039 |
T16029 |
T16028 |
prep |
with,coincident |
R5040 |
T16030 |
T16031 |
det |
a,cQTL |
R5041 |
T16031 |
T16029 |
pobj |
cQTL,with |
R5042 |
T16032 |
T16031 |
acl |
associated,cQTL |
R5043 |
T16033 |
T16032 |
prep |
with,associated |
R5044 |
T16034 |
T16035 |
compound |
fat,mass |
R5045 |
T16035 |
T16033 |
pobj |
mass,with |
R5046 |
T16036 |
T16031 |
acl |
reported,cQTL |
R5047 |
T16037 |
T16036 |
prep |
in,reported |
R5048 |
T16038 |
T16039 |
det |
this,study |
R5049 |
T16039 |
T16037 |
pobj |
study,in |
R5050 |
T16040 |
T16024 |
punct |
.,was |
R5051 |
T16042 |
T16043 |
mark |
Since,represent |
R5052 |
T16043 |
T16046 |
advcl |
represent,supports |
R5053 |
T16044 |
T16045 |
det |
these,transcripts |
R5054 |
T16045 |
T16043 |
nsubj |
transcripts,represent |
R5055 |
T16047 |
T16043 |
dobj |
those,represent |
R5056 |
T16048 |
T16049 |
advmod |
significantly,correlated |
R5057 |
T16049 |
T16047 |
acl |
correlated,those |
R5058 |
T16050 |
T16049 |
prep |
with,correlated |
R5059 |
T16051 |
T16052 |
amod |
gonadal,mass |
R5060 |
T16052 |
T16050 |
pobj |
mass,with |
R5061 |
T16053 |
T16052 |
compound |
fat,mass |
R5062 |
T16054 |
T16046 |
punct |
", ",supports |
R5063 |
T16055 |
T16056 |
det |
the,localization |
R5064 |
T16056 |
T16046 |
nsubj |
localization,supports |
R5065 |
T16057 |
T16056 |
prep |
of,localization |
R5066 |
T16058 |
T16059 |
poss |
their,eQTLs |
R5067 |
T16059 |
T16057 |
pobj |
eQTLs,of |
R5068 |
T16060 |
T16056 |
prep |
to,localization |
R5069 |
T16061 |
T16062 |
det |
these,regions |
R5070 |
T16062 |
T16060 |
pobj |
regions,to |
R5071 |
T16063 |
T16046 |
advmod |
strongly,supports |
R5072 |
T16064 |
T16065 |
det |
the,notion |
R5073 |
T16065 |
T16046 |
dobj |
notion,supports |
R5074 |
T16066 |
T16067 |
mark |
that,represent |
R5075 |
T16067 |
T16065 |
acl |
represent,notion |
R5076 |
T16068 |
T16069 |
det |
the,genes |
R5077 |
T16069 |
T16067 |
nsubj |
genes,represent |
R5078 |
T16070 |
T16069 |
prep |
with,genes |
R5079 |
T16071 |
T16072 |
compound |
trans,eQTLs |
R5080 |
T16072 |
T16070 |
pobj |
eQTLs,with |
R5081 |
T16073 |
T16072 |
punct |
-,eQTLs |
R5082 |
T16074 |
T16075 |
amod |
downstream,targets |
R5083 |
T16075 |
T16067 |
dobj |
targets,represent |
R5084 |
T16076 |
T16075 |
prep |
of,targets |
R5085 |
T16077 |
T16078 |
nmod |
candidate,genes |
R5086 |
T16078 |
T16076 |
pobj |
genes,of |
R5087 |
T16079 |
T16078 |
amod |
regulatory,genes |
R5088 |
T16080 |
T16078 |
acl |
located,genes |
R5089 |
T16081 |
T16080 |
prep |
at,located |
R5090 |
T16082 |
T16083 |
det |
the,position |
R5091 |
T16083 |
T16081 |
pobj |
position,at |
R5092 |
T16084 |
T16083 |
prep |
of,position |
R5093 |
T16085 |
T16086 |
amod |
significant,linkage |
R5094 |
T16086 |
T16084 |
pobj |
linkage,of |
R5095 |
T16087 |
T16046 |
punct |
.,supports |
R5096 |
T16089 |
T16090 |
nsubj |
This,means |
R5097 |
T16091 |
T16092 |
mark |
that,be |
R5098 |
T16092 |
T16090 |
ccomp |
be,means |
R5099 |
T16093 |
T16094 |
det |
the,genes |
R5100 |
T16094 |
T16092 |
nsubj |
genes,be |
R5101 |
T16095 |
T16092 |
aux |
may,be |
R5102 |
T16096 |
T16092 |
acomp |
causal,be |
R5103 |
T16097 |
T16096 |
cc |
but,causal |
R5104 |
T16098 |
T16096 |
conj |
downstream,causal |
R5105 |
T16099 |
T16098 |
prep |
of,downstream |
R5106 |
T16100 |
T16101 |
det |
the,gene |
R5107 |
T16101 |
T16099 |
pobj |
gene,of |
R5108 |
T16102 |
T16101 |
amod |
responsible,gene |
R5109 |
T16103 |
T16102 |
prep |
for,responsible |
R5110 |
T16104 |
T16105 |
det |
the,cQTLs |
R5111 |
T16105 |
T16103 |
pobj |
cQTLs,for |
R5112 |
T16106 |
T16092 |
punct |
", ",be |
R5113 |
T16107 |
T16092 |
cc |
or,be |
R5114 |
T16108 |
T16109 |
nsubj |
they,reacting |
R5115 |
T16109 |
T16092 |
conj |
reacting,be |
R5116 |
T16110 |
T16109 |
aux |
may,reacting |
R5117 |
T16111 |
T16109 |
aux |
be,reacting |
R5118 |
T16112 |
T16109 |
prep |
to,reacting |
R5119 |
T16113 |
T16114 |
det |
the,mass |
R5120 |
T16114 |
T16112 |
pobj |
mass,to |
R5121 |
T16115 |
T16114 |
amod |
increased,mass |
R5122 |
T16116 |
T16114 |
amod |
gonadal,mass |
R5123 |
T16117 |
T16114 |
compound |
fat,mass |
R5124 |
T16118 |
T16114 |
cc |
and,mass |
R5125 |
T16119 |
T16120 |
amod |
associated,changes |
R5126 |
T16120 |
T16114 |
conj |
changes,mass |
R5127 |
T16121 |
T16120 |
amod |
metabolic,changes |
R5128 |
T16122 |
T16090 |
punct |
.,means |
R5129 |
T16124 |
T16125 |
det |
These,data |
R5130 |
T16125 |
T16126 |
nsubj |
data,suggest |
R5131 |
T16127 |
T16126 |
advmod |
also,suggest |
R5132 |
T16128 |
T16129 |
mark |
that,is |
R5133 |
T16129 |
T16126 |
ccomp |
is,suggest |
R5134 |
T16130 |
T16129 |
csubj |
identifying,is |
R5135 |
T16131 |
T16132 |
amod |
such,loci |
R5136 |
T16132 |
T16130 |
dobj |
loci,identifying |
R5137 |
T16133 |
T16134 |
dep |
that,show |
R5138 |
T16134 |
T16132 |
relcl |
show,loci |
R5139 |
T16135 |
T16134 |
dobj |
overrepresentation,show |
R5140 |
T16136 |
T16135 |
prep |
of,overrepresentation |
R5141 |
T16137 |
T16138 |
advmod |
highly,correlated |
R5142 |
T16138 |
T16139 |
amod |
correlated,genes |
R5143 |
T16139 |
T16136 |
pobj |
genes,of |
R5144 |
T16140 |
T16141 |
det |
a,means |
R5145 |
T16141 |
T16129 |
attr |
means,is |
R5146 |
T16142 |
T16143 |
aux |
to,identify |
R5147 |
T16143 |
T16141 |
advcl |
identify,means |
R5148 |
T16144 |
T16145 |
dep |
which,controlled |
R5149 |
T16145 |
T16143 |
ccomp |
controlled,identify |
R5150 |
T16146 |
T16144 |
prep |
of,which |
R5151 |
T16147 |
T16148 |
det |
the,cQTLs |
R5152 |
T16148 |
T16146 |
pobj |
cQTLs,of |
R5153 |
T16149 |
T16148 |
compound |
trait,cQTLs |
R5154 |
T16150 |
T16145 |
auxpass |
are,controlled |
R5155 |
T16151 |
T16152 |
advmod |
more,likely |
R5156 |
T16152 |
T16145 |
advmod |
likely,controlled |
R5157 |
T16153 |
T16145 |
agent |
by,controlled |
R5158 |
T16154 |
T16155 |
det |
the,tissue |
R5159 |
T16155 |
T16153 |
pobj |
tissue,by |
R5160 |
T16156 |
T16155 |
acl |
arrayed,tissue |
R5161 |
T16157 |
T16126 |
punct |
.,suggest |
R5162 |
T16159 |
T16160 |
mark |
As,expected |
R5163 |
T16160 |
T16161 |
advcl |
expected,was |
R5164 |
T16162 |
T16161 |
punct |
", ",was |
R5165 |
T16163 |
T16164 |
det |
the,locus |
R5166 |
T16164 |
T16161 |
nsubj |
locus,was |
R5167 |
T16165 |
T16164 |
nmod |
Chromosome,locus |
R5168 |
T16166 |
T16165 |
nummod |
19,Chromosome |
R5169 |
T16167 |
T16161 |
acomp |
enriched,was |
R5170 |
T16168 |
T16167 |
prep |
for,enriched |
R5171 |
T16169 |
T16170 |
compound |
trans,eQTLs |
R5172 |
T16170 |
T16168 |
pobj |
eQTLs,for |
R5173 |
T16171 |
T16170 |
punct |
-,eQTLs |
R5174 |
T16172 |
T16161 |
prep |
with,was |
R5175 |
T16173 |
T16174 |
advmod |
substantially,greater |
R5176 |
T16174 |
T16175 |
amod |
greater,effects |
R5177 |
T16175 |
T16172 |
pobj |
effects,with |
R5178 |
T16176 |
T16175 |
prep |
in,effects |
R5179 |
T16177 |
T16176 |
pobj |
females,in |
R5180 |
T16178 |
T16161 |
punct |
.,was |
R5181 |
T16180 |
T16181 |
amod |
Functional,analysis |
R5182 |
T16181 |
T16184 |
nsubj |
analysis,prove |
R5183 |
T16182 |
T16180 |
cc |
and,Functional |
R5184 |
T16183 |
T16180 |
conj |
promoter,Functional |
R5185 |
T16185 |
T16181 |
prep |
of,analysis |
R5186 |
T16186 |
T16185 |
pobj |
genes,of |
R5187 |
T16187 |
T16181 |
prep |
with,analysis |
R5188 |
T16188 |
T16189 |
det |
a,eQTL |
R5189 |
T16189 |
T16187 |
pobj |
eQTL,with |
R5190 |
T16190 |
T16189 |
amod |
common,eQTL |
R5191 |
T16191 |
T16189 |
compound |
trans,eQTL |
R5192 |
T16192 |
T16189 |
punct |
-,eQTL |
R5193 |
T16193 |
T16184 |
aux |
may,prove |
R5194 |
T16194 |
T16184 |
oprd |
enlightening,prove |
R5195 |
T16195 |
T16184 |
punct |
.,prove |
R5196 |
T16197 |
T16198 |
advmod |
Furthermore,improved |
R5197 |
T16199 |
T16198 |
punct |
", ",improved |
R5198 |
T16200 |
T16201 |
compound |
gene,expression |
R5199 |
T16201 |
T16202 |
compound |
expression,construction |
R5200 |
T16202 |
T16198 |
nsubjpass |
construction,improved |
R5201 |
T16203 |
T16202 |
compound |
network,construction |
R5202 |
T16204 |
T16202 |
cc |
and,construction |
R5203 |
T16205 |
T16202 |
conj |
analysis,construction |
R5204 |
T16206 |
T16198 |
aux |
may,improved |
R5205 |
T16207 |
T16198 |
auxpass |
be,improved |
R5206 |
T16208 |
T16198 |
agent |
by,improved |
R5207 |
T16209 |
T16210 |
det |
the,incorporation |
R5208 |
T16210 |
T16208 |
pobj |
incorporation,by |
R5209 |
T16211 |
T16210 |
prep |
of,incorporation |
R5210 |
T16212 |
T16213 |
advmod |
experimentally,demonstrated |
R5211 |
T16213 |
T16214 |
amod |
demonstrated,regulation |
R5212 |
T16214 |
T16211 |
pobj |
regulation,of |
R5213 |
T16215 |
T16216 |
nmod |
cis,trans |
R5214 |
T16216 |
T16214 |
compound |
trans,regulation |
R5215 |
T16217 |
T16216 |
nmod |
versus,trans |
R5216 |
T16218 |
T16198 |
punct |
.,improved |