craft-sa-dev Home  

PMC:1315279 / 29141-30311 JSONTXT 4 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T6200 0-5 VBN denotes Given
T6202 6-9 DT denotes the
T6204 10-18 JJ denotes apparent
T6203 19-30 NN denotes enhancement
T6205 31-33 IN denotes of
T6206 34-45 VBN denotes mineralized
T6207 46-52 NN denotes nodule
T6208 53-62 NN denotes formation
T6209 63-65 IN denotes by
T6210 66-71 NN denotes Sam68
T6212 71-72 SYM denotes −
T6213 72-73 HYPH denotes /
T6214 73-74 SYM denotes −
T6215 75-79 NN denotes bone
T6216 80-86 NN denotes marrow
T6217 87-94 JJ denotes stromal
T6211 95-100 NNS denotes cells
T6218 101-103 FW denotes ex
T6219 104-108 FW denotes vivo
T6220 109-112 CC denotes and
T6221 113-116 DT denotes the
T6222 117-126 NN denotes phenotype
T6223 127-135 VBN denotes observed
T6224 136-140 IN denotes with
T6225 141-146 JJ denotes short
T6227 147-154 NN denotes hairpin
T6226 155-158 NN denotes RNA
T6229 159-160 -LRB- denotes (
T6230 160-165 NN denotes shRNA
T6231 165-166 -RRB- denotes )
T6232 166-167 HYPH denotes -
T6228 167-174 VBN denotes treated
T6233 175-182 NN denotes C3H10T1
T6234 182-183 HYPH denotes /
T6235 183-184 CD denotes 2
T6236 184-186 , denotes ,
T6237 186-188 PRP denotes we
T6201 189-196 VBD denotes stained
T6238 197-205 NNS denotes sections
T6239 206-208 IN denotes of
T6240 209-213 NN denotes bone
T6241 214-218 IN denotes from
T6242 219-220 CD denotes 4
T6244 220-221 HYPH denotes -
T6245 222-225 CC denotes and
T6246 226-228 CD denotes 12
T6247 228-229 HYPH denotes -
T6243 229-234 NN denotes month
T6249 234-235 HYPH denotes -
T6248 235-238 JJ denotes old
T6250 239-243 NNS denotes mice
T6251 244-247 IN denotes for
T6252 248-256 NN denotes evidence
T6253 257-259 IN denotes of
T6254 260-267 NNS denotes changes
T6255 268-270 IN denotes in
T6256 271-277 NN denotes marrow
T6257 278-287 NN denotes adiposity
T6258 287-288 . denotes .
T6259 288-606 sentence denotes Figure 9 shows sections of undecalcified bone from 4- and 12-month-old Sam68+/+ and Sam68−/− mice stained with von Kossa and toluidine blue to show mineralized tissue (Figure 9A, black) and marrow adipocytes (Figure 9B, white) and left unstained to show fluorochrome labeling of the mineralization fronts (Figure 9C).
T6260 289-295 NN denotes Figure
T6262 296-297 CD denotes 9
T6261 298-303 VBZ denotes shows
T6263 304-312 NNS denotes sections
T6264 313-315 IN denotes of
T6265 316-329 JJ denotes undecalcified
T6266 330-334 NN denotes bone
T6267 335-339 IN denotes from
T6268 340-341 CD denotes 4
T6270 341-342 HYPH denotes -
T6271 343-346 CC denotes and
T6272 347-349 CD denotes 12
T6273 349-350 HYPH denotes -
T6269 350-355 NN denotes month
T6275 355-356 HYPH denotes -
T6274 356-359 JJ denotes old
T6277 360-365 NN denotes Sam68
T6278 365-366 SYM denotes +
T6279 366-367 HYPH denotes /
T6280 367-368 SYM denotes +
T6281 369-372 CC denotes and
T6282 373-378 NN denotes Sam68
T6283 378-379 SYM denotes −
T6284 379-380 HYPH denotes /
T6285 380-381 SYM denotes −
T6276 382-386 NNS denotes mice
T6286 387-394 VBN denotes stained
T6287 395-399 IN denotes with
T6288 400-403 NNP denotes von
T6289 404-409 NNP denotes Kossa
T6290 410-413 CC denotes and
T6291 414-423 NN denotes toluidine
T6292 424-428 JJ denotes blue
T6293 429-431 TO denotes to
T6294 432-436 VB denotes show
T6295 437-448 VBN denotes mineralized
T6296 449-455 NN denotes tissue
T6297 456-457 -LRB- denotes (
T6299 457-463 NN denotes Figure
T6298 464-466 NN denotes 9A
T6300 466-468 , denotes ,
T6301 468-473 JJ denotes black
T6302 473-474 -RRB- denotes )
T6303 475-478 CC denotes and
T6304 479-485 NN denotes marrow
T6305 486-496 NNS denotes adipocytes
T6306 497-498 -LRB- denotes (
T6308 498-504 NN denotes Figure
T6307 505-507 NN denotes 9B
T6309 507-509 , denotes ,
T6310 509-514 JJ denotes white
T6311 514-515 -RRB- denotes )
T6312 516-519 CC denotes and
T6313 520-524 VBD denotes left
T6314 525-534 JJ denotes unstained
T6315 535-537 TO denotes to
T6316 538-542 VB denotes show
T6317 543-555 NN denotes fluorochrome
T6318 556-564 NN denotes labeling
T6319 565-567 IN denotes of
T6320 568-571 DT denotes the
T6322 572-586 NN denotes mineralization
T6321 587-593 NNS denotes fronts
T6323 594-595 -LRB- denotes (
T6325 595-601 NN denotes Figure
T6324 602-604 NN denotes 9C
T6326 604-605 -RRB- denotes )
T6327 605-606 . denotes .
T6328 606-859 sentence denotes Twelve-month-old Sam68+/+ mice showed a noticeable decrease in trabecular bone (Figure 9A), which was associated with a significant increase in marrow adiposity (Figure 9B) and with the two fluorochrome labels superimposed upon one another (Figure 9C).
T6329 607-613 CD denotes Twelve
T6331 613-614 HYPH denotes -
T6330 614-619 NN denotes month
T6333 619-620 HYPH denotes -
T6332 620-623 JJ denotes old
T6335 624-629 NN denotes Sam68
T6336 629-630 SYM denotes +
T6337 630-631 HYPH denotes /
T6338 631-632 SYM denotes +
T6334 633-637 NNS denotes mice
T6339 638-644 VBD denotes showed
T6340 645-646 DT denotes a
T6342 647-657 JJ denotes noticeable
T6341 658-666 NN denotes decrease
T6343 667-669 IN denotes in
T6344 670-680 JJ denotes trabecular
T6345 681-685 NN denotes bone
T6346 686-687 -LRB- denotes (
T6348 687-693 NN denotes Figure
T6347 694-696 NN denotes 9A
T6349 696-697 -RRB- denotes )
T6350 697-699 , denotes ,
T6351 699-704 WDT denotes which
T6353 705-708 VBD denotes was
T6352 709-719 VBN denotes associated
T6354 720-724 IN denotes with
T6355 725-726 DT denotes a
T6357 727-738 JJ denotes significant
T6356 739-747 NN denotes increase
T6358 748-750 IN denotes in
T6359 751-757 NN denotes marrow
T6360 758-767 NN denotes adiposity
T6361 768-769 -LRB- denotes (
T6363 769-775 NN denotes Figure
T6362 776-778 NN denotes 9B
T6364 778-779 -RRB- denotes )
T6365 780-783 CC denotes and
T6366 784-788 IN denotes with
T6367 789-792 DT denotes the
T6369 793-796 CD denotes two
T6370 797-809 NN denotes fluorochrome
T6368 810-816 NNS denotes labels
T6371 817-829 VBN denotes superimposed
T6372 830-834 IN denotes upon
T6373 835-838 CD denotes one
T6374 839-846 DT denotes another
T6375 847-848 -LRB- denotes (
T6377 848-854 NN denotes Figure
T6376 855-857 NN denotes 9C
T6378 857-858 -RRB- denotes )
T6379 858-859 . denotes .
T6380 859-982 sentence denotes In contrast, the bones of 12-month-old Sam68−/− mice appeared similar to those of the 4-month-old mice of either genotype.
T6381 860-862 IN denotes In
T6383 863-871 NN denotes contrast
T6384 871-873 , denotes ,
T6385 873-876 DT denotes the
T6386 877-882 NNS denotes bones
T6387 883-885 IN denotes of
T6388 886-888 CD denotes 12
T6390 888-889 HYPH denotes -
T6389 889-894 NN denotes month
T6392 894-895 HYPH denotes -
T6391 895-898 JJ denotes old
T6394 899-904 NN denotes Sam68
T6395 904-905 SYM denotes −
T6396 905-906 HYPH denotes /
T6397 906-907 SYM denotes −
T6393 908-912 NNS denotes mice
T6382 913-921 VBD denotes appeared
T6398 922-929 JJ denotes similar
T6399 930-932 IN denotes to
T6400 933-938 DT denotes those
T6401 939-941 IN denotes of
T6402 942-945 DT denotes the
T6404 946-947 CD denotes 4
T6406 947-948 HYPH denotes -
T6405 948-953 NN denotes month
T6408 953-954 HYPH denotes -
T6407 954-957 JJ denotes old
T6403 958-962 NNS denotes mice
T6409 963-965 IN denotes of
T6410 966-972 DT denotes either
T6411 973-981 NN denotes genotype
T6412 981-982 . denotes .
T6413 982-1170 sentence denotes These data demonstrate that Sam68 regulates the differentiation of bone marrow mesenchymal cells to promote adipocyte differentiation and inhibit osteoblast differentiation in aging bone.
T6414 983-988 DT denotes These
T6415 989-993 NNS denotes data
T6416 994-1005 VBP denotes demonstrate
T6417 1006-1010 IN denotes that
T6419 1011-1016 NN denotes Sam68
T6418 1017-1026 VBZ denotes regulates
T6420 1027-1030 DT denotes the
T6421 1031-1046 NN denotes differentiation
T6422 1047-1049 IN denotes of
T6423 1050-1054 NN denotes bone
T6424 1055-1061 NN denotes marrow
T6426 1062-1073 JJ denotes mesenchymal
T6425 1074-1079 NNS denotes cells
T6427 1080-1082 TO denotes to
T6428 1083-1090 VB denotes promote
T6429 1091-1100 NN denotes adipocyte
T6430 1101-1116 NN denotes differentiation
T6431 1117-1120 CC denotes and
T6432 1121-1128 VB denotes inhibit
T6433 1129-1139 NN denotes osteoblast
T6434 1140-1155 NN denotes differentiation
T6435 1156-1158 IN denotes in
T6436 1159-1164 VBG denotes aging
T6437 1165-1169 NN denotes bone
T6438 1169-1170 . denotes .
R3856 T6200 T6201 prep Given,stained
R3857 T6202 T6203 det the,enhancement
R3858 T6203 T6200 pobj enhancement,Given
R3859 T6204 T6203 amod apparent,enhancement
R3860 T6205 T6203 prep of,enhancement
R3861 T6206 T6207 amod mineralized,nodule
R3862 T6207 T6208 compound nodule,formation
R3863 T6208 T6205 pobj formation,of
R3864 T6209 T6203 prep by,enhancement
R3865 T6210 T6211 nmod Sam68,cells
R3866 T6211 T6209 pobj cells,by
R3867 T6212 T6210 punct −,Sam68
R3868 T6213 T6210 punct /,Sam68
R3869 T6214 T6210 punct −,Sam68
R3870 T6215 T6216 nmod bone,marrow
R3871 T6216 T6211 nmod marrow,cells
R3872 T6217 T6211 amod stromal,cells
R3873 T6218 T6219 advmod ex,vivo
R3874 T6219 T6203 advmod vivo,enhancement
R3875 T6220 T6203 cc and,enhancement
R3876 T6221 T6222 det the,phenotype
R3877 T6222 T6203 conj phenotype,enhancement
R3878 T6223 T6222 acl observed,phenotype
R3879 T6224 T6223 prep with,observed
R3880 T6225 T6226 amod short,RNA
R3881 T6226 T6228 npadvmod RNA,treated
R3882 T6227 T6226 compound hairpin,RNA
R3883 T6228 T6233 amod treated,C3H10T1
R3884 T6229 T6226 punct (,RNA
R3885 T6230 T6226 appos shRNA,RNA
R3886 T6231 T6228 punct ),treated
R3887 T6232 T6228 punct -,treated
R3888 T6233 T6224 pobj C3H10T1,with
R3889 T6234 T6233 punct /,C3H10T1
R3890 T6235 T6233 nummod 2,C3H10T1
R3891 T6236 T6201 punct ", ",stained
R3892 T6237 T6201 nsubj we,stained
R3893 T6238 T6201 dobj sections,stained
R3894 T6239 T6238 prep of,sections
R3895 T6240 T6239 pobj bone,of
R3896 T6241 T6238 prep from,sections
R3897 T6242 T6243 nummod 4,month
R3898 T6243 T6248 npadvmod month,old
R3899 T6244 T6242 punct -,4
R3900 T6245 T6242 cc and,4
R3901 T6246 T6242 conj 12,4
R3902 T6247 T6243 punct -,month
R3903 T6248 T6250 amod old,mice
R3904 T6249 T6248 punct -,old
R3905 T6250 T6241 pobj mice,from
R3906 T6251 T6201 prep for,stained
R3907 T6252 T6251 pobj evidence,for
R3908 T6253 T6252 prep of,evidence
R3909 T6254 T6253 pobj changes,of
R3910 T6255 T6254 prep in,changes
R3911 T6256 T6257 compound marrow,adiposity
R3912 T6257 T6255 pobj adiposity,in
R3913 T6258 T6201 punct .,stained
R3914 T6260 T6261 nsubj Figure,shows
R3915 T6262 T6260 nummod 9,Figure
R3916 T6263 T6261 dobj sections,shows
R3917 T6264 T6263 prep of,sections
R3918 T6265 T6266 amod undecalcified,bone
R3919 T6266 T6264 pobj bone,of
R3920 T6267 T6266 prep from,bone
R3921 T6268 T6269 nummod 4,month
R3922 T6269 T6274 npadvmod month,old
R3923 T6270 T6268 punct -,4
R3924 T6271 T6268 cc and,4
R3925 T6272 T6268 conj 12,4
R3926 T6273 T6269 punct -,month
R3927 T6274 T6276 amod old,mice
R3928 T6275 T6274 punct -,old
R3929 T6276 T6267 pobj mice,from
R3930 T6277 T6276 nmod Sam68,mice
R3931 T6278 T6277 punct +,Sam68
R3932 T6279 T6277 punct /,Sam68
R3933 T6280 T6277 punct +,Sam68
R3934 T6281 T6277 cc and,Sam68
R3935 T6282 T6277 conj Sam68,Sam68
R3936 T6283 T6282 punct −,Sam68
R3937 T6284 T6282 punct /,Sam68
R3938 T6285 T6282 punct −,Sam68
R3939 T6286 T6276 acl stained,mice
R3940 T6287 T6286 prep with,stained
R3941 T6288 T6289 compound von,Kossa
R3942 T6289 T6287 pobj Kossa,with
R3943 T6290 T6289 cc and,Kossa
R3944 T6291 T6289 conj toluidine,Kossa
R3945 T6292 T6291 amod blue,toluidine
R3946 T6293 T6294 aux to,show
R3947 T6294 T6286 advcl show,stained
R3948 T6295 T6296 amod mineralized,tissue
R3949 T6296 T6294 dobj tissue,show
R3950 T6297 T6298 punct (,9A
R3951 T6298 T6296 parataxis 9A,tissue
R3952 T6299 T6298 compound Figure,9A
R3953 T6300 T6298 punct ", ",9A
R3954 T6301 T6298 amod black,9A
R3955 T6302 T6298 punct ),9A
R3956 T6303 T6296 cc and,tissue
R3957 T6304 T6305 compound marrow,adipocytes
R3958 T6305 T6296 conj adipocytes,tissue
R3959 T6306 T6307 punct (,9B
R3960 T6307 T6305 parataxis 9B,adipocytes
R3961 T6308 T6307 compound Figure,9B
R3962 T6309 T6307 punct ", ",9B
R3963 T6310 T6307 amod white,9B
R3964 T6311 T6307 punct ),9B
R3965 T6312 T6286 cc and,stained
R3966 T6313 T6286 conj left,stained
R3967 T6314 T6313 oprd unstained,left
R3968 T6315 T6316 aux to,show
R3969 T6316 T6313 advcl show,left
R3970 T6317 T6318 compound fluorochrome,labeling
R3971 T6318 T6316 dobj labeling,show
R3972 T6319 T6318 prep of,labeling
R3973 T6320 T6321 det the,fronts
R3974 T6321 T6319 pobj fronts,of
R3975 T6322 T6321 compound mineralization,fronts
R3976 T6323 T6324 punct (,9C
R3977 T6324 T6316 parataxis 9C,show
R3978 T6325 T6324 compound Figure,9C
R3979 T6326 T6324 punct ),9C
R3980 T6327 T6261 punct .,shows
R3981 T6329 T6330 nummod Twelve,month
R3982 T6330 T6332 npadvmod month,old
R3983 T6331 T6330 punct -,month
R3984 T6332 T6334 amod old,mice
R3985 T6333 T6332 punct -,old
R3986 T6334 T6339 nsubj mice,showed
R3987 T6335 T6334 nmod Sam68,mice
R3988 T6336 T6335 punct +,Sam68
R3989 T6337 T6335 punct /,Sam68
R3990 T6338 T6335 punct +,Sam68
R3991 T6340 T6341 det a,decrease
R3992 T6341 T6339 dobj decrease,showed
R3993 T6342 T6341 amod noticeable,decrease
R3994 T6343 T6341 prep in,decrease
R3995 T6344 T6345 amod trabecular,bone
R3996 T6345 T6343 pobj bone,in
R3997 T6346 T6347 punct (,9A
R3998 T6347 T6345 parataxis 9A,bone
R3999 T6348 T6347 compound Figure,9A
R4000 T6349 T6347 punct ),9A
R4001 T6350 T6341 punct ", ",decrease
R4002 T6351 T6352 dep which,associated
R4003 T6352 T6341 relcl associated,decrease
R4004 T6353 T6352 auxpass was,associated
R4005 T6354 T6352 prep with,associated
R4006 T6355 T6356 det a,increase
R4007 T6356 T6354 pobj increase,with
R4008 T6357 T6356 amod significant,increase
R4009 T6358 T6356 prep in,increase
R4010 T6359 T6360 compound marrow,adiposity
R4011 T6360 T6358 pobj adiposity,in
R4012 T6361 T6362 punct (,9B
R4013 T6362 T6356 parataxis 9B,increase
R4014 T6363 T6362 compound Figure,9B
R4015 T6364 T6362 punct ),9B
R4016 T6365 T6354 cc and,with
R4017 T6366 T6354 conj with,with
R4018 T6367 T6368 det the,labels
R4019 T6368 T6366 pobj labels,with
R4020 T6369 T6368 nummod two,labels
R4021 T6370 T6368 compound fluorochrome,labels
R4022 T6371 T6368 acl superimposed,labels
R4023 T6372 T6371 prep upon,superimposed
R4024 T6373 T6372 pobj one,upon
R4025 T6374 T6373 det another,one
R4026 T6375 T6376 punct (,9C
R4027 T6376 T6368 parataxis 9C,labels
R4028 T6377 T6376 compound Figure,9C
R4029 T6378 T6376 punct ),9C
R4030 T6379 T6339 punct .,showed
R4031 T6381 T6382 prep In,appeared
R4032 T6383 T6381 pobj contrast,In
R4033 T6384 T6382 punct ", ",appeared
R4034 T6385 T6386 det the,bones
R4035 T6386 T6382 nsubj bones,appeared
R4036 T6387 T6386 prep of,bones
R4037 T6388 T6389 nummod 12,month
R4038 T6389 T6391 npadvmod month,old
R4039 T6390 T6389 punct -,month
R4040 T6391 T6393 amod old,mice
R4041 T6392 T6391 punct -,old
R4042 T6393 T6387 pobj mice,of
R4043 T6394 T6393 nmod Sam68,mice
R4044 T6395 T6394 punct −,Sam68
R4045 T6396 T6394 punct /,Sam68
R4046 T6397 T6394 punct −,Sam68
R4047 T6398 T6382 oprd similar,appeared
R4048 T6399 T6398 prep to,similar
R4049 T6400 T6399 pobj those,to
R4050 T6401 T6400 prep of,those
R4051 T6402 T6403 det the,mice
R4052 T6403 T6401 pobj mice,of
R4053 T6404 T6405 nummod 4,month
R4054 T6405 T6407 npadvmod month,old
R4055 T6406 T6405 punct -,month
R4056 T6407 T6403 amod old,mice
R4057 T6408 T6407 punct -,old
R4058 T6409 T6403 prep of,mice
R4059 T6410 T6411 det either,genotype
R4060 T6411 T6409 pobj genotype,of
R4061 T6412 T6382 punct .,appeared
R4062 T6414 T6415 det These,data
R4063 T6415 T6416 nsubj data,demonstrate
R4064 T6417 T6418 mark that,regulates
R4065 T6418 T6416 ccomp regulates,demonstrate
R4066 T6419 T6418 nsubj Sam68,regulates
R4067 T6420 T6421 det the,differentiation
R4068 T6421 T6418 dobj differentiation,regulates
R4069 T6422 T6421 prep of,differentiation
R4070 T6423 T6424 nmod bone,marrow
R4071 T6424 T6425 nmod marrow,cells
R4072 T6425 T6422 pobj cells,of
R4073 T6426 T6425 amod mesenchymal,cells
R4074 T6427 T6428 aux to,promote
R4075 T6428 T6418 advcl promote,regulates
R4076 T6429 T6430 compound adipocyte,differentiation
R4077 T6430 T6428 dobj differentiation,promote
R4078 T6431 T6428 cc and,promote
R4079 T6432 T6428 conj inhibit,promote
R4080 T6433 T6434 compound osteoblast,differentiation
R4081 T6434 T6432 dobj differentiation,inhibit
R4082 T6435 T6428 prep in,promote
R4083 T6436 T6437 amod aging,bone
R4084 T6437 T6435 pobj bone,in
R4085 T6438 T6416 punct .,demonstrate