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PMC:1315279 / 22085-24686 JSONTXT 5 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T4956 0-10 NN denotes Osteoblast
T4958 10-12 , denotes ,
T4959 12-15 CC denotes but
T4960 16-19 RB denotes Not
T4961 20-30 NN denotes Osteoclast
T4962 30-32 , denotes ,
T4957 32-40 NN denotes Activity
T4964 41-43 VBZ denotes Is
T4963 44-51 VBN denotes Altered
T4965 52-54 IN denotes in
T4966 55-60 NN denotes Sam68
T4968 60-61 SYM denotes −
T4969 61-62 HYPH denotes /
T4970 62-63 SYM denotes −
T4967 64-68 NNS denotes Mice
T4971 69-71 FW denotes Ex
T4972 72-76 FW denotes Vivo
T4973 76-255 sentence denotes Maintenance of bone mass during the adult remodeling cycle is dependent on the coupling of osteoblast to osteoclast activity, such that there is no net gain or loss of bone [49].
T4974 77-88 NN denotes Maintenance
T4976 89-91 IN denotes of
T4977 92-96 NN denotes bone
T4978 97-101 NN denotes mass
T4979 102-108 IN denotes during
T4980 109-112 DT denotes the
T4982 113-118 JJ denotes adult
T4983 119-129 NN denotes remodeling
T4981 130-135 NN denotes cycle
T4975 136-138 VBZ denotes is
T4984 139-148 JJ denotes dependent
T4985 149-151 IN denotes on
T4986 152-155 DT denotes the
T4987 156-164 NN denotes coupling
T4988 165-167 IN denotes of
T4989 168-178 NN denotes osteoblast
T4990 179-181 IN denotes to
T4991 182-192 NN denotes osteoclast
T4992 193-201 NN denotes activity
T4993 201-203 , denotes ,
T4994 203-207 JJ denotes such
T4996 208-212 IN denotes that
T4997 213-218 EX denotes there
T4995 219-221 VBZ denotes is
T4998 222-224 DT denotes no
T5000 225-228 JJ denotes net
T4999 229-233 NN denotes gain
T5001 234-236 CC denotes or
T5002 237-241 NN denotes loss
T5003 242-244 IN denotes of
T5004 245-249 NN denotes bone
T5005 250-251 -LRB- denotes [
T5006 251-253 CD denotes 49
T5007 253-254 -RRB- denotes ]
T5008 254-255 . denotes .
T5009 255-456 sentence denotes To further explore the age-related advantage of Sam68−/− mice with respect to bone preservation, we examined the functional activity of Sam68−/− osteoblasts and osteoclasts ex vivo (Figure 6A and 6B).
T5010 256-258 TO denotes To
T5012 259-266 RB denotes further
T5011 267-274 VB denotes explore
T5014 275-278 DT denotes the
T5016 279-282 NN denotes age
T5018 282-283 HYPH denotes -
T5017 283-290 VBN denotes related
T5015 291-300 NN denotes advantage
T5019 301-303 IN denotes of
T5020 304-309 NN denotes Sam68
T5022 309-310 SYM denotes −
T5023 310-311 HYPH denotes /
T5024 311-312 SYM denotes −
T5021 313-317 NNS denotes mice
T5025 318-322 IN denotes with
T5026 323-330 NN denotes respect
T5027 331-333 IN denotes to
T5028 334-338 NN denotes bone
T5029 339-351 NN denotes preservation
T5030 351-353 , denotes ,
T5031 353-355 PRP denotes we
T5013 356-364 VBD denotes examined
T5032 365-368 DT denotes the
T5034 369-379 JJ denotes functional
T5033 380-388 NN denotes activity
T5035 389-391 IN denotes of
T5036 392-397 NN denotes Sam68
T5037 397-398 SYM denotes −
T5038 398-399 HYPH denotes /
T5039 399-400 SYM denotes −
T5040 401-412 NNS denotes osteoblasts
T5041 413-416 CC denotes and
T5042 417-428 NNS denotes osteoclasts
T5043 429-431 FW denotes ex
T5044 432-436 FW denotes vivo
T5045 437-438 -LRB- denotes (
T5047 438-444 NN denotes Figure
T5046 445-447 NN denotes 6A
T5048 448-451 CC denotes and
T5049 452-454 NN denotes 6B
T5050 454-455 -RRB- denotes )
T5051 455-456 . denotes .
T5052 456-879 sentence denotes Cultures of bone marrow stromal cells harvested from 4-week-old Sam68−/− mice and maintained for 18 days in osteoblast differentiation medium demonstrated more intense staining for ALP at 6 days (unpublished data) and 18 days (Figure 6A), and more mineralized nodules at 18 days, than the Sam68+/+ mice, even though similar amounts of fibroblast colony-forming units (CFU-F) were observed (Figure 6A and unpublished data).
T5053 457-465 NNS denotes Cultures
T5055 466-468 IN denotes of
T5056 469-473 NN denotes bone
T5057 474-480 NN denotes marrow
T5059 481-488 JJ denotes stromal
T5058 489-494 NNS denotes cells
T5060 495-504 VBN denotes harvested
T5061 505-509 IN denotes from
T5062 510-511 CD denotes 4
T5064 511-512 HYPH denotes -
T5063 512-516 NN denotes week
T5066 516-517 HYPH denotes -
T5065 517-520 JJ denotes old
T5068 521-526 NN denotes Sam68
T5069 526-527 SYM denotes −
T5070 527-528 HYPH denotes /
T5071 528-529 SYM denotes −
T5067 530-534 NNS denotes mice
T5072 535-538 CC denotes and
T5073 539-549 VBN denotes maintained
T5074 550-553 IN denotes for
T5075 554-556 CD denotes 18
T5076 557-561 NNS denotes days
T5077 562-564 IN denotes in
T5078 565-575 NN denotes osteoblast
T5079 576-591 NN denotes differentiation
T5080 592-598 NN denotes medium
T5054 599-611 VBD denotes demonstrated
T5081 612-616 RBR denotes more
T5082 617-624 JJ denotes intense
T5083 625-633 NN denotes staining
T5084 634-637 IN denotes for
T5085 638-641 NN denotes ALP
T5086 642-644 IN denotes at
T5087 645-646 CD denotes 6
T5088 647-651 NNS denotes days
T5089 652-653 -LRB- denotes (
T5091 653-664 JJ denotes unpublished
T5090 665-669 NNS denotes data
T5092 669-670 -RRB- denotes )
T5093 671-674 CC denotes and
T5094 675-677 CD denotes 18
T5095 678-682 NNS denotes days
T5096 683-684 -LRB- denotes (
T5098 684-690 NN denotes Figure
T5097 691-693 NN denotes 6A
T5099 693-694 NN denotes )
T5100 694-696 NN denotes ,
T5101 696-699 CC denotes and
T5102 700-704 JJR denotes more
T5104 705-716 VBN denotes mineralized
T5103 717-724 NNS denotes nodules
T5105 725-727 IN denotes at
T5106 728-730 CD denotes 18
T5107 731-735 NNS denotes days
T5108 735-737 NN denotes ,
T5109 737-741 IN denotes than
T5110 742-745 DT denotes the
T5112 746-751 NN denotes Sam68
T5113 751-752 SYM denotes +
T5114 752-753 HYPH denotes /
T5115 753-754 SYM denotes +
T5111 755-759 NNS denotes mice
T5116 759-761 NN denotes ,
T5117 761-765 RB denotes even
T5119 766-772 IN denotes though
T5120 773-780 JJ denotes similar
T5121 781-788 NNS denotes amounts
T5122 789-791 IN denotes of
T5123 792-802 NN denotes fibroblast
T5125 803-809 NN denotes colony
T5127 809-810 HYPH denotes -
T5126 810-817 VBG denotes forming
T5124 818-823 NNS denotes units
T5128 824-825 -LRB- denotes (
T5129 825-828 NN denotes CFU
T5131 828-829 HYPH denotes -
T5130 829-830 NN denotes F
T5132 830-831 -RRB- denotes )
T5133 832-836 VBD denotes were
T5118 837-845 VBN denotes observed
T5134 846-847 -LRB- denotes (
T5136 847-853 NN denotes Figure
T5135 854-856 NN denotes 6A
T5137 857-860 CC denotes and
T5138 861-872 JJ denotes unpublished
T5139 873-877 NNS denotes data
T5140 877-878 -RRB- denotes )
T5141 878-879 . denotes .
T5142 879-1130 sentence denotes RT-PCR analysis of molecular markers of osteoblast differentiation (Dataset S2) revealed similar increases over time in RNA from Sam68+/+ and Sam68−/− mice, although type I collagen appeared to be up-regulated at both timepoints in the Sam68−/− mice.
T5143 880-882 NN denotes RT
T5145 882-883 HYPH denotes -
T5144 883-886 NN denotes PCR
T5146 887-895 NN denotes analysis
T5148 896-898 IN denotes of
T5149 899-908 JJ denotes molecular
T5150 909-916 NNS denotes markers
T5151 917-919 IN denotes of
T5152 920-930 NN denotes osteoblast
T5153 931-946 NN denotes differentiation
T5154 947-948 -LRB- denotes (
T5156 948-955 NN denotes Dataset
T5155 956-958 NN denotes S2
T5157 958-959 -RRB- denotes )
T5147 960-968 VBD denotes revealed
T5158 969-976 JJ denotes similar
T5159 977-986 NNS denotes increases
T5160 987-991 IN denotes over
T5161 992-996 NN denotes time
T5162 997-999 IN denotes in
T5163 1000-1003 NN denotes RNA
T5164 1004-1008 IN denotes from
T5165 1009-1014 NN denotes Sam68
T5167 1014-1015 SYM denotes +
T5168 1015-1016 HYPH denotes /
T5169 1016-1017 SYM denotes +
T5170 1018-1021 CC denotes and
T5171 1022-1027 NN denotes Sam68
T5172 1027-1028 SYM denotes −
T5173 1028-1029 HYPH denotes /
T5174 1029-1030 SYM denotes −
T5166 1031-1035 NNS denotes mice
T5175 1035-1037 , denotes ,
T5176 1037-1045 IN denotes although
T5178 1046-1050 NN denotes type
T5180 1051-1052 CD denotes I
T5179 1053-1061 NN denotes collagen
T5177 1062-1070 VBD denotes appeared
T5181 1071-1073 TO denotes to
T5183 1074-1076 VB denotes be
T5184 1077-1079 RB denotes up
T5185 1079-1080 HYPH denotes -
T5182 1080-1089 VBN denotes regulated
T5186 1090-1092 IN denotes at
T5187 1093-1097 DT denotes both
T5188 1098-1108 NNS denotes timepoints
T5189 1109-1111 IN denotes in
T5190 1112-1115 DT denotes the
T5192 1116-1121 NN denotes Sam68
T5193 1121-1122 SYM denotes −
T5194 1122-1123 HYPH denotes /
T5195 1123-1124 SYM denotes −
T5191 1125-1129 NNS denotes mice
T5196 1129-1130 . denotes .
T5197 1130-1410 sentence denotes Short-term cultures of mature osteoclasts released from the crushed long bones of Sam68+/+ and Sam68−/− mice stained equally well for TRAP and excavated approximately equal numbers of pits of equal size in dentin slices, as visualized by scanning electron microscopy (Figure 6B).
T5198 1131-1136 JJ denotes Short
T5200 1136-1137 HYPH denotes -
T5199 1137-1141 NN denotes term
T5201 1142-1150 NNS denotes cultures
T5203 1151-1153 IN denotes of
T5204 1154-1160 JJ denotes mature
T5205 1161-1172 NNS denotes osteoclasts
T5206 1173-1181 VBN denotes released
T5207 1182-1186 IN denotes from
T5208 1187-1190 DT denotes the
T5210 1191-1198 JJ denotes crushed
T5211 1199-1203 JJ denotes long
T5209 1204-1209 NNS denotes bones
T5212 1210-1212 IN denotes of
T5213 1213-1218 NN denotes Sam68
T5215 1218-1219 SYM denotes +
T5216 1219-1220 HYPH denotes /
T5217 1220-1221 SYM denotes +
T5218 1222-1225 CC denotes and
T5219 1226-1231 NN denotes Sam68
T5220 1231-1232 SYM denotes −
T5221 1232-1233 HYPH denotes /
T5222 1233-1234 SYM denotes −
T5214 1235-1239 NNS denotes mice
T5202 1240-1247 VBD denotes stained
T5223 1248-1255 RB denotes equally
T5224 1256-1260 RB denotes well
T5225 1261-1264 IN denotes for
T5226 1265-1269 NN denotes TRAP
T5227 1270-1273 CC denotes and
T5228 1274-1283 VBD denotes excavated
T5229 1284-1297 RB denotes approximately
T5230 1298-1303 JJ denotes equal
T5231 1304-1311 NNS denotes numbers
T5232 1312-1314 IN denotes of
T5233 1315-1319 NNS denotes pits
T5234 1320-1322 IN denotes of
T5235 1323-1328 JJ denotes equal
T5236 1329-1333 NN denotes size
T5237 1334-1336 IN denotes in
T5238 1337-1343 NN denotes dentin
T5239 1344-1350 NNS denotes slices
T5240 1350-1352 , denotes ,
T5241 1352-1354 IN denotes as
T5242 1355-1365 VBN denotes visualized
T5243 1366-1368 IN denotes by
T5244 1369-1377 VBG denotes scanning
T5245 1378-1386 NN denotes electron
T5246 1387-1397 NN denotes microscopy
T5247 1398-1399 -LRB- denotes (
T5249 1399-1405 NN denotes Figure
T5248 1406-1408 NN denotes 6B
T5250 1408-1409 -RRB- denotes )
T5251 1409-1410 . denotes .
T5252 1410-1537 sentence denotes These findings suggest that the osteoclasts may not be the primary defect in Sam68−/− mice, as they are in Src null mice [48].
T5253 1411-1416 DT denotes These
T5254 1417-1425 NNS denotes findings
T5255 1426-1433 VBP denotes suggest
T5256 1434-1438 IN denotes that
T5258 1439-1442 DT denotes the
T5259 1443-1454 NNS denotes osteoclasts
T5260 1455-1458 MD denotes may
T5261 1459-1462 RB denotes not
T5257 1463-1465 VB denotes be
T5262 1466-1469 DT denotes the
T5264 1470-1477 JJ denotes primary
T5263 1478-1484 NN denotes defect
T5265 1485-1487 IN denotes in
T5266 1488-1493 NN denotes Sam68
T5268 1493-1494 SYM denotes −
T5269 1494-1495 HYPH denotes /
T5270 1495-1496 SYM denotes −
T5267 1497-1501 NNS denotes mice
T5271 1501-1503 , denotes ,
T5272 1503-1505 IN denotes as
T5274 1506-1510 PRP denotes they
T5273 1511-1514 VBP denotes are
T5275 1515-1517 IN denotes in
T5276 1518-1521 NN denotes Src
T5278 1522-1526 JJ denotes null
T5277 1527-1531 NNS denotes mice
T5279 1532-1533 -LRB- denotes [
T5280 1533-1535 CD denotes 48
T5281 1535-1536 -RRB- denotes ]
T5282 1536-1537 . denotes .
R3052 T4956 T4957 nmod Osteoblast,Activity
R3053 T4957 T4963 nsubjpass Activity,Altered
R3054 T4958 T4956 punct ", ",Osteoblast
R3055 T4959 T4956 cc but,Osteoblast
R3056 T4960 T4959 neg Not,but
R3057 T4961 T4956 conj Osteoclast,Osteoblast
R3058 T4962 T4957 punct ", ",Activity
R3059 T4964 T4963 auxpass Is,Altered
R3060 T4965 T4963 prep in,Altered
R3061 T4966 T4967 nmod Sam68,Mice
R3062 T4967 T4965 pobj Mice,in
R3063 T4968 T4966 punct −,Sam68
R3064 T4969 T4966 punct /,Sam68
R3065 T4970 T4966 punct −,Sam68
R3066 T4971 T4972 advmod Ex,Vivo
R3067 T4972 T4963 advmod Vivo,Altered
R3068 T4974 T4975 nsubj Maintenance,is
R3069 T4976 T4974 prep of,Maintenance
R3070 T4977 T4978 compound bone,mass
R3071 T4978 T4976 pobj mass,of
R3072 T4979 T4974 prep during,Maintenance
R3073 T4980 T4981 det the,cycle
R3074 T4981 T4979 pobj cycle,during
R3075 T4982 T4981 amod adult,cycle
R3076 T4983 T4981 compound remodeling,cycle
R3077 T4984 T4975 acomp dependent,is
R3078 T4985 T4984 prep on,dependent
R3079 T4986 T4987 det the,coupling
R3080 T4987 T4985 pobj coupling,on
R3081 T4988 T4987 prep of,coupling
R3082 T4989 T4988 pobj osteoblast,of
R3083 T4990 T4987 prep to,coupling
R3084 T4991 T4990 pobj osteoclast,to
R3085 T4992 T4987 appos activity,coupling
R3086 T4993 T4975 punct ", ",is
R3087 T4994 T4995 amod such,is
R3088 T4995 T4975 advcl is,is
R3089 T4996 T4995 mark that,is
R3090 T4997 T4995 expl there,is
R3091 T4998 T4999 det no,gain
R3092 T4999 T4995 attr gain,is
R3093 T5000 T4999 amod net,gain
R3094 T5001 T4999 cc or,gain
R3095 T5002 T4999 conj loss,gain
R3096 T5003 T4999 prep of,gain
R3097 T5004 T5003 pobj bone,of
R3098 T5005 T5006 punct [,49
R3099 T5006 T4975 parataxis 49,is
R3100 T5007 T5006 punct ],49
R3101 T5008 T4975 punct .,is
R3102 T5010 T5011 aux To,explore
R3103 T5011 T5013 advcl explore,examined
R3104 T5012 T5011 advmod further,explore
R3105 T5014 T5015 det the,advantage
R3106 T5015 T5011 dobj advantage,explore
R3107 T5016 T5017 npadvmod age,related
R3108 T5017 T5015 amod related,advantage
R3109 T5018 T5017 punct -,related
R3110 T5019 T5015 prep of,advantage
R3111 T5020 T5021 nmod Sam68,mice
R3112 T5021 T5019 pobj mice,of
R3113 T5022 T5020 punct −,Sam68
R3114 T5023 T5020 punct /,Sam68
R3115 T5024 T5020 punct −,Sam68
R3116 T5025 T5011 prep with,explore
R3117 T5026 T5025 pobj respect,with
R3118 T5027 T5026 prep to,respect
R3119 T5028 T5029 compound bone,preservation
R3120 T5029 T5027 pobj preservation,to
R3121 T5030 T5013 punct ", ",examined
R3122 T5031 T5013 nsubj we,examined
R3123 T5032 T5033 det the,activity
R3124 T5033 T5013 dobj activity,examined
R3125 T5034 T5033 amod functional,activity
R3126 T5035 T5033 prep of,activity
R3127 T5036 T5035 pobj Sam68,of
R3128 T5037 T5036 punct −,Sam68
R3129 T5038 T5036 punct /,Sam68
R3130 T5039 T5036 punct −,Sam68
R3131 T5040 T5036 appos osteoblasts,Sam68
R3132 T5041 T5040 cc and,osteoblasts
R3133 T5042 T5040 conj osteoclasts,osteoblasts
R3134 T5043 T5044 advmod ex,vivo
R3135 T5044 T5013 advmod vivo,examined
R3136 T5045 T5046 punct (,6A
R3137 T5046 T5013 parataxis 6A,examined
R3138 T5047 T5046 compound Figure,6A
R3139 T5048 T5046 cc and,6A
R3140 T5049 T5046 conj 6B,6A
R3141 T5050 T5046 punct ),6A
R3142 T5051 T5013 punct .,examined
R3143 T5053 T5054 nsubj Cultures,demonstrated
R3144 T5055 T5053 prep of,Cultures
R3145 T5056 T5057 nmod bone,marrow
R3146 T5057 T5058 nmod marrow,cells
R3147 T5058 T5055 pobj cells,of
R3148 T5059 T5058 amod stromal,cells
R3149 T5060 T5053 acl harvested,Cultures
R3150 T5061 T5060 prep from,harvested
R3151 T5062 T5063 nummod 4,week
R3152 T5063 T5065 npadvmod week,old
R3153 T5064 T5063 punct -,week
R3154 T5065 T5067 amod old,mice
R3155 T5066 T5065 punct -,old
R3156 T5067 T5061 pobj mice,from
R3157 T5068 T5067 nmod Sam68,mice
R3158 T5069 T5068 punct −,Sam68
R3159 T5070 T5068 punct /,Sam68
R3160 T5071 T5068 punct −,Sam68
R3161 T5072 T5060 cc and,harvested
R3162 T5073 T5060 conj maintained,harvested
R3163 T5074 T5073 prep for,maintained
R3164 T5075 T5076 nummod 18,days
R3165 T5076 T5074 pobj days,for
R3166 T5077 T5073 prep in,maintained
R3167 T5078 T5079 compound osteoblast,differentiation
R3168 T5079 T5080 compound differentiation,medium
R3169 T5080 T5077 pobj medium,in
R3170 T5081 T5082 advmod more,intense
R3171 T5082 T5083 amod intense,staining
R3172 T5083 T5054 dobj staining,demonstrated
R3173 T5084 T5083 prep for,staining
R3174 T5085 T5084 pobj ALP,for
R3175 T5086 T5054 prep at,demonstrated
R3176 T5087 T5088 nummod 6,days
R3177 T5088 T5086 pobj days,at
R3178 T5089 T5090 punct (,data
R3179 T5090 T5088 meta data,days
R3180 T5091 T5090 amod unpublished,data
R3181 T5092 T5090 punct ),data
R3182 T5093 T5088 cc and,days
R3183 T5094 T5095 nummod 18,days
R3184 T5095 T5088 conj days,days
R3185 T5096 T5097 punct (,6A
R3186 T5097 T5095 parataxis 6A,days
R3187 T5098 T5097 compound Figure,6A
R3188 T5099 T5097 dep ),6A
R3189 T5100 T5054 dep ", ",demonstrated
R3190 T5101 T5054 cc and,demonstrated
R3191 T5102 T5103 amod more,nodules
R3192 T5103 T5054 conj nodules,demonstrated
R3193 T5104 T5103 amod mineralized,nodules
R3194 T5105 T5103 prep at,nodules
R3195 T5106 T5107 nummod 18,days
R3196 T5107 T5105 pobj days,at
R3197 T5108 T5054 dep ", ",demonstrated
R3198 T5109 T5054 prep than,demonstrated
R3199 T5110 T5111 det the,mice
R3200 T5111 T5109 pobj mice,than
R3201 T5112 T5111 nmod Sam68,mice
R3202 T5113 T5112 punct +,Sam68
R3203 T5114 T5112 punct /,Sam68
R3204 T5115 T5112 punct +,Sam68
R3205 T5116 T5054 dep ", ",demonstrated
R3206 T5117 T5118 advmod even,observed
R3207 T5118 T5054 advcl observed,demonstrated
R3208 T5119 T5118 mark though,observed
R3209 T5120 T5121 amod similar,amounts
R3210 T5121 T5118 nsubjpass amounts,observed
R3211 T5122 T5121 prep of,amounts
R3212 T5123 T5124 nmod fibroblast,units
R3213 T5124 T5122 pobj units,of
R3214 T5125 T5126 npadvmod colony,forming
R3215 T5126 T5124 amod forming,units
R3216 T5127 T5126 punct -,forming
R3217 T5128 T5124 punct (,units
R3218 T5129 T5130 compound CFU,F
R3219 T5130 T5124 appos F,units
R3220 T5131 T5130 punct -,F
R3221 T5132 T5118 punct ),observed
R3222 T5133 T5118 auxpass were,observed
R3223 T5134 T5135 punct (,6A
R3224 T5135 T5118 parataxis 6A,observed
R3225 T5136 T5135 compound Figure,6A
R3226 T5137 T5135 cc and,6A
R3227 T5138 T5139 amod unpublished,data
R3228 T5139 T5135 conj data,6A
R3229 T5140 T5135 punct ),6A
R3230 T5141 T5054 punct .,demonstrated
R3231 T5143 T5144 compound RT,PCR
R3232 T5144 T5146 compound PCR,analysis
R3233 T5145 T5144 punct -,PCR
R3234 T5146 T5147 nsubj analysis,revealed
R3235 T5148 T5146 prep of,analysis
R3236 T5149 T5150 amod molecular,markers
R3237 T5150 T5148 pobj markers,of
R3238 T5151 T5150 prep of,markers
R3239 T5152 T5153 compound osteoblast,differentiation
R3240 T5153 T5151 pobj differentiation,of
R3241 T5154 T5155 punct (,S2
R3242 T5155 T5146 parataxis S2,analysis
R3243 T5156 T5155 compound Dataset,S2
R3244 T5157 T5155 punct ),S2
R3245 T5158 T5159 amod similar,increases
R3246 T5159 T5147 dobj increases,revealed
R3247 T5160 T5147 prep over,revealed
R3248 T5161 T5160 pobj time,over
R3249 T5162 T5147 prep in,revealed
R3250 T5163 T5162 pobj RNA,in
R3251 T5164 T5163 prep from,RNA
R3252 T5165 T5166 nmod Sam68,mice
R3253 T5166 T5164 pobj mice,from
R3254 T5167 T5165 punct +,Sam68
R3255 T5168 T5165 punct /,Sam68
R3256 T5169 T5165 punct +,Sam68
R3257 T5170 T5165 cc and,Sam68
R3258 T5171 T5165 conj Sam68,Sam68
R3259 T5172 T5171 punct −,Sam68
R3260 T5173 T5171 punct /,Sam68
R3261 T5174 T5171 punct −,Sam68
R3262 T5175 T5147 punct ", ",revealed
R3263 T5176 T5177 mark although,appeared
R3264 T5177 T5147 advcl appeared,revealed
R3265 T5178 T5179 nmod type,collagen
R3266 T5179 T5177 nsubj collagen,appeared
R3267 T5180 T5178 nummod I,type
R3268 T5181 T5182 aux to,regulated
R3269 T5182 T5177 xcomp regulated,appeared
R3270 T5183 T5182 auxpass be,regulated
R3271 T5184 T5182 advmod up,regulated
R3272 T5185 T5182 punct -,regulated
R3273 T5186 T5182 prep at,regulated
R3274 T5187 T5188 det both,timepoints
R3275 T5188 T5186 pobj timepoints,at
R3276 T5189 T5182 prep in,regulated
R3277 T5190 T5191 det the,mice
R3278 T5191 T5189 pobj mice,in
R3279 T5192 T5191 nmod Sam68,mice
R3280 T5193 T5192 punct −,Sam68
R3281 T5194 T5192 punct /,Sam68
R3282 T5195 T5192 punct −,Sam68
R3283 T5196 T5147 punct .,revealed
R3284 T5198 T5199 amod Short,term
R3285 T5199 T5201 compound term,cultures
R3286 T5200 T5199 punct -,term
R3287 T5201 T5202 nsubj cultures,stained
R3288 T5203 T5201 prep of,cultures
R3289 T5204 T5205 amod mature,osteoclasts
R3290 T5205 T5203 pobj osteoclasts,of
R3291 T5206 T5205 acl released,osteoclasts
R3292 T5207 T5206 prep from,released
R3293 T5208 T5209 det the,bones
R3294 T5209 T5207 pobj bones,from
R3295 T5210 T5209 amod crushed,bones
R3296 T5211 T5209 amod long,bones
R3297 T5212 T5209 prep of,bones
R3298 T5213 T5214 nmod Sam68,mice
R3299 T5214 T5212 pobj mice,of
R3300 T5215 T5213 punct +,Sam68
R3301 T5216 T5213 punct /,Sam68
R3302 T5217 T5213 punct +,Sam68
R3303 T5218 T5213 cc and,Sam68
R3304 T5219 T5213 conj Sam68,Sam68
R3305 T5220 T5219 punct −,Sam68
R3306 T5221 T5219 punct /,Sam68
R3307 T5222 T5219 punct −,Sam68
R3308 T5223 T5224 advmod equally,well
R3309 T5224 T5202 advmod well,stained
R3310 T5225 T5202 prep for,stained
R3311 T5226 T5225 pobj TRAP,for
R3312 T5227 T5202 cc and,stained
R3313 T5228 T5202 conj excavated,stained
R3314 T5229 T5230 advmod approximately,equal
R3315 T5230 T5231 amod equal,numbers
R3316 T5231 T5228 dobj numbers,excavated
R3317 T5232 T5231 prep of,numbers
R3318 T5233 T5232 pobj pits,of
R3319 T5234 T5233 prep of,pits
R3320 T5235 T5236 amod equal,size
R3321 T5236 T5234 pobj size,of
R3322 T5237 T5228 prep in,excavated
R3323 T5238 T5239 compound dentin,slices
R3324 T5239 T5237 pobj slices,in
R3325 T5240 T5228 punct ", ",excavated
R3326 T5241 T5242 mark as,visualized
R3327 T5242 T5228 advcl visualized,excavated
R3328 T5243 T5242 prep by,visualized
R3329 T5244 T5243 pcomp scanning,by
R3330 T5245 T5246 compound electron,microscopy
R3331 T5246 T5244 dobj microscopy,scanning
R3332 T5247 T5248 punct (,6B
R3333 T5248 T5228 parataxis 6B,excavated
R3334 T5249 T5248 compound Figure,6B
R3335 T5250 T5248 punct ),6B
R3336 T5251 T5202 punct .,stained
R3337 T5253 T5254 det These,findings
R3338 T5254 T5255 nsubj findings,suggest
R3339 T5256 T5257 mark that,be
R3340 T5257 T5255 ccomp be,suggest
R3341 T5258 T5259 det the,osteoclasts
R3342 T5259 T5257 nsubj osteoclasts,be
R3343 T5260 T5257 aux may,be
R3344 T5261 T5257 neg not,be
R3345 T5262 T5263 det the,defect
R3346 T5263 T5257 attr defect,be
R3347 T5264 T5263 amod primary,defect
R3348 T5265 T5263 prep in,defect
R3349 T5266 T5267 nmod Sam68,mice
R3350 T5267 T5265 pobj mice,in
R3351 T5268 T5266 punct −,Sam68
R3352 T5269 T5266 punct /,Sam68
R3353 T5270 T5266 punct −,Sam68
R3354 T5271 T5257 punct ", ",be
R3355 T5272 T5273 mark as,are
R3356 T5273 T5257 advcl are,be
R3357 T5274 T5273 nsubj they,are
R3358 T5275 T5273 prep in,are
R3359 T5276 T5277 nmod Src,mice
R3360 T5277 T5275 pobj mice,in
R3361 T5278 T5277 amod null,mice
R3362 T5279 T5280 punct [,48
R3363 T5280 T5273 parataxis 48,are
R3364 T5281 T5280 punct ],48
R3365 T5282 T5255 punct .,suggest