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PMC:1315279 / 18631-19625 JSONTXT 5 Projects

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Id Subject Object Predicate Lexical cue
T4175 0-2 TO denotes To
T4177 3-10 RB denotes further
T4176 11-17 VB denotes define
T4179 18-21 DT denotes the
T4180 22-32 NNS denotes mechanisms
T4181 33-41 VBN denotes involved
T4182 42-44 IN denotes in
T4183 45-48 DT denotes the
T4184 49-61 NN denotes preservation
T4185 62-64 IN denotes of
T4186 65-69 NN denotes bone
T4187 70-74 NN denotes mass
T4188 75-77 IN denotes in
T4189 78-82 JJ denotes aged
T4191 83-88 NN denotes Sam68
T4192 88-89 SYM denotes −
T4193 89-90 HYPH denotes /
T4194 90-91 SYM denotes −
T4190 92-96 NNS denotes mice
T4195 96-98 , denotes ,
T4196 98-100 PRP denotes we
T4178 101-109 VBD denotes prepared
T4197 110-118 NNS denotes sections
T4198 119-123 IN denotes from
T4199 124-131 NN denotes plastic
T4201 131-132 HYPH denotes -
T4200 132-140 VBN denotes embedded
T4202 141-147 NNS denotes femora
T4203 148-151 CC denotes and
T4204 152-157 NN denotes tibia
T4205 158-160 TO denotes to
T4206 161-169 VB denotes evaluate
T4207 170-180 NN denotes osteoblast
T4209 181-184 CC denotes and
T4210 185-195 NN denotes osteoclast
T4208 196-204 NN denotes activity
T4211 205-206 -LRB- denotes (
T4212 206-212 NN denotes Figure
T4213 213-214 CD denotes 5
T4214 214-215 -RRB- denotes )
T4215 215-216 . denotes .
T4216 216-468 sentence denotes In situ enzyme histochemical staining for alkaline phosphatase (ALP; brown stain) activity was used as a biomarker for osteoblasts and tartrate-resistant ALP (tartrate-resistant acid phosphatase [TRAP]; red stain) activity as a marker for osteoclasts.
T4217 217-219 FW denotes In
T4218 220-224 FW denotes situ
T4220 225-231 NN denotes enzyme
T4221 232-245 JJ denotes histochemical
T4219 246-254 NN denotes staining
T4223 255-258 IN denotes for
T4224 259-267 NN denotes alkaline
T4225 268-279 NN denotes phosphatase
T4227 280-281 -LRB- denotes (
T4228 281-284 NN denotes ALP
T4229 284-285 : denotes ;
T4231 286-291 JJ denotes brown
T4230 292-297 NN denotes stain
T4232 297-298 -RRB- denotes )
T4226 299-307 NN denotes activity
T4233 308-311 VBD denotes was
T4222 312-316 VBN denotes used
T4234 317-319 IN denotes as
T4235 320-321 DT denotes a
T4236 322-331 NN denotes biomarker
T4237 332-335 IN denotes for
T4238 336-347 NNS denotes osteoblasts
T4239 348-351 CC denotes and
T4240 352-360 NN denotes tartrate
T4242 360-361 HYPH denotes -
T4241 361-370 JJ denotes resistant
T4244 371-374 NN denotes ALP
T4245 375-376 -LRB- denotes (
T4247 376-384 NN denotes tartrate
T4249 384-385 HYPH denotes -
T4248 385-394 JJ denotes resistant
T4251 395-399 NN denotes acid
T4250 400-411 NN denotes phosphatase
T4252 412-413 -LRB- denotes [
T4253 413-417 NN denotes TRAP
T4254 417-418 -RRB- denotes ]
T4255 418-419 : denotes ;
T4256 420-423 JJ denotes red
T4246 424-429 NN denotes stain
T4257 429-430 -RRB- denotes )
T4243 431-439 NN denotes activity
T4258 440-442 IN denotes as
T4259 443-444 DT denotes a
T4260 445-451 NN denotes marker
T4261 452-455 IN denotes for
T4262 456-467 NNS denotes osteoclasts
T4263 467-468 . denotes .
T4264 468-588 sentence denotes Little difference was seen between Sam68+/+ (Figure 5A and 5B) and Sam68−/− (Figure 5C and 5D) mice at 4 months of age.
T4265 469-475 JJ denotes Little
T4266 476-486 NN denotes difference
T4268 487-490 VBD denotes was
T4267 491-495 VBN denotes seen
T4269 496-503 IN denotes between
T4270 504-509 NN denotes Sam68
T4272 509-510 SYM denotes +
T4273 510-511 HYPH denotes /
T4274 511-512 SYM denotes +
T4275 513-514 -LRB- denotes (
T4277 514-520 NN denotes Figure
T4276 521-523 NN denotes 5A
T4278 524-527 CC denotes and
T4279 528-530 NN denotes 5B
T4280 530-531 -RRB- denotes )
T4281 532-535 CC denotes and
T4282 536-541 NN denotes Sam68
T4283 541-542 SYM denotes −
T4284 542-543 HYPH denotes /
T4285 543-544 SYM denotes −
T4286 545-546 -LRB- denotes (
T4288 546-552 NN denotes Figure
T4287 553-555 NN denotes 5C
T4289 556-559 CC denotes and
T4290 560-562 NN denotes 5D
T4291 562-563 -RRB- denotes )
T4271 564-568 NNS denotes mice
T4292 569-571 IN denotes at
T4293 572-573 CD denotes 4
T4294 574-580 NNS denotes months
T4295 581-583 IN denotes of
T4296 584-587 NN denotes age
T4297 587-588 . denotes .
T4298 588-756 sentence denotes ALP- and TRAP-positive cells were reduced in the 12-month-old Sam68+/+ mice (Figure 5E and 5F) and remained unchanged in 12-month-old Sam68−/− mice (Figure 5G and 5H).
T4299 589-592 NN denotes ALP
T4301 592-593 HYPH denotes -
T4302 594-597 CC denotes and
T4303 598-602 NN denotes TRAP
T4304 602-603 HYPH denotes -
T4300 603-611 JJ denotes positive
T4305 612-617 NNS denotes cells
T4307 618-622 VBD denotes were
T4306 623-630 VBN denotes reduced
T4308 631-633 IN denotes in
T4309 634-637 DT denotes the
T4311 638-640 CD denotes 12
T4313 640-641 HYPH denotes -
T4312 641-646 NN denotes month
T4315 646-647 HYPH denotes -
T4314 647-650 JJ denotes old
T4316 651-656 NN denotes Sam68
T4317 656-657 SYM denotes +
T4318 657-658 HYPH denotes /
T4319 658-659 SYM denotes +
T4310 660-664 NNS denotes mice
T4320 665-666 -LRB- denotes (
T4322 666-672 NN denotes Figure
T4321 673-675 NN denotes 5E
T4323 676-679 CC denotes and
T4324 680-682 NN denotes 5F
T4325 682-683 -RRB- denotes )
T4326 684-687 CC denotes and
T4327 688-696 VBD denotes remained
T4328 697-706 JJ denotes unchanged
T4329 707-709 IN denotes in
T4330 710-712 CD denotes 12
T4332 712-713 HYPH denotes -
T4331 713-718 NN denotes month
T4334 718-719 HYPH denotes -
T4333 719-722 JJ denotes old
T4336 723-728 NN denotes Sam68
T4337 728-729 SYM denotes −
T4338 729-730 HYPH denotes /
T4339 730-731 SYM denotes −
T4335 732-736 NNS denotes mice
T4340 737-738 -LRB- denotes (
T4342 738-744 NN denotes Figure
T4341 745-747 NN denotes 5G
T4343 748-751 CC denotes and
T4344 752-754 NN denotes 5H
T4345 754-755 -RRB- denotes )
T4346 755-756 . denotes .
T4347 756-994 sentence denotes The reduction in both osteoblast and osteoclast activity in the 12-month-old Sam68+/+ mice argued against bone being lost primarily due to a relative increase in osteoclast over osteoblast activity, as seen in high turnover disease [49].
T4348 757-760 DT denotes The
T4349 761-770 NN denotes reduction
T4351 771-773 IN denotes in
T4352 774-778 CC denotes both
T4353 779-789 NN denotes osteoblast
T4355 790-793 CC denotes and
T4356 794-804 NN denotes osteoclast
T4354 805-813 NN denotes activity
T4357 814-816 IN denotes in
T4358 817-820 DT denotes the
T4360 821-823 CD denotes 12
T4362 823-824 HYPH denotes -
T4361 824-829 NN denotes month
T4364 829-830 HYPH denotes -
T4363 830-833 JJ denotes old
T4365 834-839 NN denotes Sam68
T4366 839-840 SYM denotes +
T4367 840-841 HYPH denotes /
T4368 841-842 SYM denotes +
T4359 843-847 NNS denotes mice
T4350 848-854 VBD denotes argued
T4369 855-862 IN denotes against
T4370 863-867 NN denotes bone
T4372 868-873 VBG denotes being
T4371 874-878 VBN denotes lost
T4373 879-888 RB denotes primarily
T4374 889-892 IN denotes due
T4375 893-895 IN denotes to
T4376 896-897 DT denotes a
T4378 898-906 JJ denotes relative
T4377 907-915 NN denotes increase
T4379 916-918 IN denotes in
T4380 919-929 NN denotes osteoclast
T4381 930-934 IN denotes over
T4382 935-945 NN denotes osteoblast
T4383 946-954 NN denotes activity
T4384 954-956 , denotes ,
T4385 956-958 IN denotes as
T4386 959-963 VBN denotes seen
T4387 964-966 IN denotes in
T4388 967-971 JJ denotes high
T4389 972-980 NN denotes turnover
T4390 981-988 NN denotes disease
T4391 989-990 -LRB- denotes [
T4392 990-992 CD denotes 49
T4393 992-993 -RRB- denotes ]
T4394 993-994 . denotes .
R2468 T4175 T4176 aux To,define
R2469 T4176 T4178 advcl define,prepared
R2470 T4177 T4176 advmod further,define
R2471 T4179 T4180 det the,mechanisms
R2472 T4180 T4176 dobj mechanisms,define
R2473 T4181 T4180 acl involved,mechanisms
R2474 T4182 T4181 prep in,involved
R2475 T4183 T4184 det the,preservation
R2476 T4184 T4182 pobj preservation,in
R2477 T4185 T4184 prep of,preservation
R2478 T4186 T4187 compound bone,mass
R2479 T4187 T4185 pobj mass,of
R2480 T4188 T4184 prep in,preservation
R2481 T4189 T4190 amod aged,mice
R2482 T4190 T4188 pobj mice,in
R2483 T4191 T4190 nmod Sam68,mice
R2484 T4192 T4191 punct −,Sam68
R2485 T4193 T4191 punct /,Sam68
R2486 T4194 T4191 punct −,Sam68
R2487 T4195 T4178 punct ", ",prepared
R2488 T4196 T4178 nsubj we,prepared
R2489 T4197 T4178 dobj sections,prepared
R2490 T4198 T4178 prep from,prepared
R2491 T4199 T4200 npadvmod plastic,embedded
R2492 T4200 T4202 amod embedded,femora
R2493 T4201 T4200 punct -,embedded
R2494 T4202 T4198 pobj femora,from
R2495 T4203 T4202 cc and,femora
R2496 T4204 T4202 conj tibia,femora
R2497 T4205 T4206 aux to,evaluate
R2498 T4206 T4178 advcl evaluate,prepared
R2499 T4207 T4208 nmod osteoblast,activity
R2500 T4208 T4206 dobj activity,evaluate
R2501 T4209 T4207 cc and,osteoblast
R2502 T4210 T4207 conj osteoclast,osteoblast
R2503 T4211 T4212 punct (,Figure
R2504 T4212 T4178 parataxis Figure,prepared
R2505 T4213 T4212 nummod 5,Figure
R2506 T4214 T4212 punct ),Figure
R2507 T4215 T4178 punct .,prepared
R2508 T4217 T4218 advmod In,situ
R2509 T4218 T4219 amod situ,staining
R2510 T4219 T4222 nsubjpass staining,used
R2511 T4220 T4219 nmod enzyme,staining
R2512 T4221 T4219 amod histochemical,staining
R2513 T4223 T4219 prep for,staining
R2514 T4224 T4225 nmod alkaline,phosphatase
R2515 T4225 T4226 nmod phosphatase,activity
R2516 T4226 T4223 pobj activity,for
R2517 T4227 T4225 punct (,phosphatase
R2518 T4228 T4225 appos ALP,phosphatase
R2519 T4229 T4230 punct ;,stain
R2520 T4230 T4228 parataxis stain,ALP
R2521 T4231 T4230 amod brown,stain
R2522 T4232 T4230 punct ),stain
R2523 T4233 T4222 auxpass was,used
R2524 T4234 T4222 prep as,used
R2525 T4235 T4236 det a,biomarker
R2526 T4236 T4234 pobj biomarker,as
R2527 T4237 T4236 prep for,biomarker
R2528 T4238 T4237 pobj osteoblasts,for
R2529 T4239 T4238 cc and,osteoblasts
R2530 T4240 T4241 npadvmod tartrate,resistant
R2531 T4241 T4243 amod resistant,activity
R2532 T4242 T4241 punct -,resistant
R2533 T4243 T4238 conj activity,osteoblasts
R2534 T4244 T4243 nmod ALP,activity
R2535 T4245 T4246 punct (,stain
R2536 T4246 T4243 parataxis stain,activity
R2537 T4247 T4248 npadvmod tartrate,resistant
R2538 T4248 T4250 amod resistant,phosphatase
R2539 T4249 T4248 punct -,resistant
R2540 T4250 T4246 dep phosphatase,stain
R2541 T4251 T4250 compound acid,phosphatase
R2542 T4252 T4250 punct [,phosphatase
R2543 T4253 T4250 appos TRAP,phosphatase
R2544 T4254 T4246 punct ],stain
R2545 T4255 T4246 punct ;,stain
R2546 T4256 T4246 amod red,stain
R2547 T4257 T4246 punct ),stain
R2548 T4258 T4222 prep as,used
R2549 T4259 T4260 det a,marker
R2550 T4260 T4258 pobj marker,as
R2551 T4261 T4260 prep for,marker
R2552 T4262 T4261 pobj osteoclasts,for
R2553 T4263 T4222 punct .,used
R2554 T4265 T4266 amod Little,difference
R2555 T4266 T4267 nsubjpass difference,seen
R2556 T4268 T4267 auxpass was,seen
R2557 T4269 T4267 prep between,seen
R2558 T4270 T4271 nmod Sam68,mice
R2559 T4271 T4269 pobj mice,between
R2560 T4272 T4270 punct +,Sam68
R2561 T4273 T4270 punct /,Sam68
R2562 T4274 T4270 punct +,Sam68
R2563 T4275 T4276 punct (,5A
R2564 T4276 T4270 parataxis 5A,Sam68
R2565 T4277 T4276 compound Figure,5A
R2566 T4278 T4276 cc and,5A
R2567 T4279 T4276 conj 5B,5A
R2568 T4280 T4276 punct ),5A
R2569 T4281 T4270 cc and,Sam68
R2570 T4282 T4270 conj Sam68,Sam68
R2571 T4283 T4282 punct −,Sam68
R2572 T4284 T4282 punct /,Sam68
R2573 T4285 T4282 punct −,Sam68
R2574 T4286 T4287 punct (,5C
R2575 T4287 T4282 parataxis 5C,Sam68
R2576 T4288 T4287 compound Figure,5C
R2577 T4289 T4287 cc and,5C
R2578 T4290 T4287 conj 5D,5C
R2579 T4291 T4287 punct ),5C
R2580 T4292 T4267 prep at,seen
R2581 T4293 T4294 nummod 4,months
R2582 T4294 T4292 pobj months,at
R2583 T4295 T4294 prep of,months
R2584 T4296 T4295 pobj age,of
R2585 T4297 T4267 punct .,seen
R2586 T4299 T4300 npadvmod ALP,positive
R2587 T4300 T4305 amod positive,cells
R2588 T4301 T4299 punct -,ALP
R2589 T4302 T4299 cc and,ALP
R2590 T4303 T4299 conj TRAP,ALP
R2591 T4304 T4300 punct -,positive
R2592 T4305 T4306 nsubjpass cells,reduced
R2593 T4307 T4306 auxpass were,reduced
R2594 T4308 T4306 prep in,reduced
R2595 T4309 T4310 det the,mice
R2596 T4310 T4308 pobj mice,in
R2597 T4311 T4312 nummod 12,month
R2598 T4312 T4314 npadvmod month,old
R2599 T4313 T4312 punct -,month
R2600 T4314 T4310 amod old,mice
R2601 T4315 T4314 punct -,old
R2602 T4316 T4310 nmod Sam68,mice
R2603 T4317 T4316 punct +,Sam68
R2604 T4318 T4316 punct /,Sam68
R2605 T4319 T4316 punct +,Sam68
R2606 T4320 T4321 punct (,5E
R2607 T4321 T4306 parataxis 5E,reduced
R2608 T4322 T4321 compound Figure,5E
R2609 T4323 T4321 cc and,5E
R2610 T4324 T4321 conj 5F,5E
R2611 T4325 T4321 punct ),5E
R2612 T4326 T4306 cc and,reduced
R2613 T4327 T4306 conj remained,reduced
R2614 T4328 T4327 acomp unchanged,remained
R2615 T4329 T4327 prep in,remained
R2616 T4330 T4331 nummod 12,month
R2617 T4331 T4333 npadvmod month,old
R2618 T4332 T4331 punct -,month
R2619 T4333 T4335 amod old,mice
R2620 T4334 T4333 punct -,old
R2621 T4335 T4329 pobj mice,in
R2622 T4336 T4335 nmod Sam68,mice
R2623 T4337 T4336 punct −,Sam68
R2624 T4338 T4336 punct /,Sam68
R2625 T4339 T4336 punct −,Sam68
R2626 T4340 T4341 punct (,5G
R2627 T4341 T4327 parataxis 5G,remained
R2628 T4342 T4341 compound Figure,5G
R2629 T4343 T4341 cc and,5G
R2630 T4344 T4341 conj 5H,5G
R2631 T4345 T4341 punct ),5G
R2632 T4346 T4306 punct .,reduced
R2633 T4348 T4349 det The,reduction
R2634 T4349 T4350 nsubj reduction,argued
R2635 T4351 T4349 prep in,reduction
R2636 T4352 T4353 preconj both,osteoblast
R2637 T4353 T4354 nmod osteoblast,activity
R2638 T4354 T4351 pobj activity,in
R2639 T4355 T4353 cc and,osteoblast
R2640 T4356 T4353 conj osteoclast,osteoblast
R2641 T4357 T4349 prep in,reduction
R2642 T4358 T4359 det the,mice
R2643 T4359 T4357 pobj mice,in
R2644 T4360 T4361 nummod 12,month
R2645 T4361 T4363 npadvmod month,old
R2646 T4362 T4361 punct -,month
R2647 T4363 T4359 amod old,mice
R2648 T4364 T4363 punct -,old
R2649 T4365 T4359 nmod Sam68,mice
R2650 T4366 T4365 punct +,Sam68
R2651 T4367 T4365 punct /,Sam68
R2652 T4368 T4365 punct +,Sam68
R2653 T4369 T4350 prep against,argued
R2654 T4370 T4371 nsubjpass bone,lost
R2655 T4371 T4369 pcomp lost,against
R2656 T4372 T4371 auxpass being,lost
R2657 T4373 T4374 advmod primarily,due
R2658 T4374 T4371 prep due,lost
R2659 T4375 T4374 pcomp to,due
R2660 T4376 T4377 det a,increase
R2661 T4377 T4374 pobj increase,due
R2662 T4378 T4377 amod relative,increase
R2663 T4379 T4377 prep in,increase
R2664 T4380 T4379 pobj osteoclast,in
R2665 T4381 T4380 prep over,osteoclast
R2666 T4382 T4381 pobj osteoblast,over
R2667 T4383 T4380 appos activity,osteoclast
R2668 T4384 T4371 punct ", ",lost
R2669 T4385 T4386 mark as,seen
R2670 T4386 T4371 advcl seen,lost
R2671 T4387 T4386 prep in,seen
R2672 T4388 T4389 amod high,turnover
R2673 T4389 T4390 compound turnover,disease
R2674 T4390 T4387 pobj disease,in
R2675 T4391 T4392 punct [,49
R2676 T4392 T4350 parataxis 49,argued
R2677 T4393 T4392 punct ],49
R2678 T4394 T4350 punct .,argued