PMC:1255741 / 27877-28587 4 Projects
Annnotations
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T6400 | 0-2 | IN | denotes | In |
T6402 | 3-10 | NN | denotes | summary |
T6403 | 10-12 | , | denotes | , |
T6404 | 12-16 | NNS | denotes | mice |
T6405 | 17-21 | IN | denotes | with |
T6406 | 22-29 | VBN | denotes | reduced |
T6408 | 30-34 | NN | denotes | GluR |
T6410 | 34-35 | HYPH | denotes | - |
T6409 | 35-36 | NN | denotes | B |
T6407 | 37-43 | NNS | denotes | levels |
T6411 | 44-46 | IN | denotes | in |
T6412 | 47-56 | NN | denotes | forebrain |
T6413 | 57-62 | NNS | denotes | areas |
T6401 | 63-69 | VBD | denotes | showed |
T6414 | 70-79 | VBN | denotes | decreased |
T6416 | 80-89 | JJ | denotes | olfactory |
T6415 | 90-96 | NN | denotes | memory |
T6417 | 96-98 | , | denotes | , |
T6418 | 98-103 | WDT | denotes | which |
T6419 | 104-114 | VBD | denotes | correlated |
T6420 | 115-122 | RB | denotes | tightly |
T6421 | 123-127 | IN | denotes | with |
T6422 | 128-129 | DT | denotes | a |
T6423 | 130-139 | NN | denotes | reduction |
T6424 | 140-142 | IN | denotes | in |
T6425 | 143-147 | NN | denotes | GluR |
T6427 | 147-148 | HYPH | denotes | - |
T6426 | 148-149 | NN | denotes | B |
T6428 | 150-156 | NNS | denotes | levels |
T6429 | 157-159 | IN | denotes | in |
T6430 | 160-163 | DT | denotes | the |
T6431 | 164-175 | NN | denotes | hippocampus |
T6432 | 176-179 | CC | denotes | and |
T6433 | 180-188 | JJ | denotes | cortical |
T6434 | 189-194 | NNS | denotes | areas |
T6435 | 194-195 | . | denotes | . |
T6436 | 195-461 | sentence | denotes | Enhanced odor learning and discrimination, on the other hand, was independent of residual GluR-B levels in the olfactory bulb and other forebrain areas, indicating that moderate GluR-B reductions are sufficient to saturate enhanced odor learning and discrimination. |
T6437 | 196-204 | VBN | denotes | Enhanced |
T6439 | 205-209 | NN | denotes | odor |
T6438 | 210-218 | NN | denotes | learning |
T6441 | 219-222 | CC | denotes | and |
T6442 | 223-237 | NN | denotes | discrimination |
T6443 | 237-239 | , | denotes | , |
T6444 | 239-241 | IN | denotes | on |
T6445 | 242-245 | DT | denotes | the |
T6447 | 246-251 | JJ | denotes | other |
T6446 | 252-256 | NN | denotes | hand |
T6448 | 256-258 | , | denotes | , |
T6440 | 258-261 | VBD | denotes | was |
T6449 | 262-273 | JJ | denotes | independent |
T6450 | 274-276 | IN | denotes | of |
T6451 | 277-285 | JJ | denotes | residual |
T6453 | 286-290 | NN | denotes | GluR |
T6455 | 290-291 | HYPH | denotes | - |
T6454 | 291-292 | NN | denotes | B |
T6452 | 293-299 | NNS | denotes | levels |
T6456 | 300-302 | IN | denotes | in |
T6457 | 303-306 | DT | denotes | the |
T6459 | 307-316 | JJ | denotes | olfactory |
T6458 | 317-321 | NN | denotes | bulb |
T6460 | 322-325 | CC | denotes | and |
T6461 | 326-331 | JJ | denotes | other |
T6463 | 332-341 | NN | denotes | forebrain |
T6462 | 342-347 | NNS | denotes | areas |
T6464 | 347-349 | , | denotes | , |
T6465 | 349-359 | VBG | denotes | indicating |
T6466 | 360-364 | IN | denotes | that |
T6468 | 365-373 | JJ | denotes | moderate |
T6470 | 374-378 | NN | denotes | GluR |
T6472 | 378-379 | HYPH | denotes | - |
T6471 | 379-380 | NN | denotes | B |
T6469 | 381-391 | NNS | denotes | reductions |
T6467 | 392-395 | VBP | denotes | are |
T6473 | 396-406 | JJ | denotes | sufficient |
T6474 | 407-409 | TO | denotes | to |
T6475 | 410-418 | VB | denotes | saturate |
T6476 | 419-427 | VBN | denotes | enhanced |
T6478 | 428-432 | NN | denotes | odor |
T6477 | 433-441 | NN | denotes | learning |
T6479 | 442-445 | CC | denotes | and |
T6480 | 446-460 | NN | denotes | discrimination |
T6481 | 460-461 | . | denotes | . |
T6482 | 461-710 | sentence | denotes | Thus, although both are mediated by alterations in the AMPAR subunit GluR-B, due to the qualitatively different dose-response curves, the phenotypes regarding olfactory memory, and olfactory learning/discrimination must be mechanistically distinct. |
T6483 | 462-466 | RB | denotes | Thus |
T6485 | 466-468 | , | denotes | , |
T6486 | 468-476 | IN | denotes | although |
T6488 | 477-481 | DT | denotes | both |
T6489 | 482-485 | VBP | denotes | are |
T6487 | 486-494 | VBN | denotes | mediated |
T6490 | 495-497 | IN | denotes | by |
T6491 | 498-509 | NNS | denotes | alterations |
T6492 | 510-512 | IN | denotes | in |
T6493 | 513-516 | DT | denotes | the |
T6495 | 517-522 | NN | denotes | AMPAR |
T6494 | 523-530 | NN | denotes | subunit |
T6496 | 531-535 | NN | denotes | GluR |
T6498 | 535-536 | HYPH | denotes | - |
T6497 | 536-537 | NN | denotes | B |
T6499 | 537-539 | , | denotes | , |
T6500 | 539-542 | IN | denotes | due |
T6501 | 543-545 | IN | denotes | to |
T6502 | 546-549 | DT | denotes | the |
T6504 | 550-563 | RB | denotes | qualitatively |
T6505 | 564-573 | JJ | denotes | different |
T6506 | 574-578 | NN | denotes | dose |
T6508 | 578-579 | HYPH | denotes | - |
T6507 | 579-587 | NN | denotes | response |
T6503 | 588-594 | NNS | denotes | curves |
T6509 | 594-596 | , | denotes | , |
T6510 | 596-599 | DT | denotes | the |
T6511 | 600-610 | NNS | denotes | phenotypes |
T6512 | 611-620 | VBG | denotes | regarding |
T6513 | 621-630 | JJ | denotes | olfactory |
T6514 | 631-637 | NN | denotes | memory |
T6515 | 637-639 | , | denotes | , |
T6516 | 639-642 | CC | denotes | and |
T6517 | 643-652 | JJ | denotes | olfactory |
T6519 | 653-661 | NN | denotes | learning |
T6520 | 661-662 | HYPH | denotes | / |
T6518 | 662-676 | NN | denotes | discrimination |
T6521 | 677-681 | MD | denotes | must |
T6484 | 682-684 | VB | denotes | be |
T6522 | 685-700 | RB | denotes | mechanistically |
T6523 | 701-709 | JJ | denotes | distinct |
T6524 | 709-710 | . | denotes | . |
R4314 | T6400 | T6401 | prep | In,showed |
R4315 | T6402 | T6400 | pobj | summary,In |
R4316 | T6403 | T6401 | punct | ", ",showed |
R4317 | T6404 | T6401 | nsubj | mice,showed |
R4318 | T6405 | T6404 | prep | with,mice |
R4319 | T6406 | T6407 | amod | reduced,levels |
R4320 | T6407 | T6405 | pobj | levels,with |
R4321 | T6408 | T6409 | compound | GluR,B |
R4322 | T6409 | T6407 | compound | B,levels |
R4323 | T6410 | T6409 | punct | -,B |
R4324 | T6411 | T6407 | prep | in,levels |
R4325 | T6412 | T6413 | compound | forebrain,areas |
R4326 | T6413 | T6411 | pobj | areas,in |
R4327 | T6414 | T6415 | amod | decreased,memory |
R4328 | T6415 | T6401 | dobj | memory,showed |
R4329 | T6416 | T6415 | amod | olfactory,memory |
R4330 | T6417 | T6415 | punct | ", ",memory |
R4331 | T6418 | T6419 | dep | which,correlated |
R4332 | T6419 | T6415 | relcl | correlated,memory |
R4333 | T6420 | T6419 | advmod | tightly,correlated |
R4334 | T6421 | T6419 | prep | with,correlated |
R4335 | T6422 | T6423 | det | a,reduction |
R4336 | T6423 | T6421 | pobj | reduction,with |
R4337 | T6424 | T6423 | prep | in,reduction |
R4338 | T6425 | T6426 | compound | GluR,B |
R4339 | T6426 | T6428 | compound | B,levels |
R4340 | T6427 | T6426 | punct | -,B |
R4341 | T6428 | T6424 | pobj | levels,in |
R4342 | T6429 | T6423 | prep | in,reduction |
R4343 | T6430 | T6431 | det | the,hippocampus |
R4344 | T6431 | T6429 | pobj | hippocampus,in |
R4345 | T6432 | T6431 | cc | and,hippocampus |
R4346 | T6433 | T6434 | amod | cortical,areas |
R4347 | T6434 | T6431 | conj | areas,hippocampus |
R4348 | T6435 | T6401 | punct | .,showed |
R4349 | T6437 | T6438 | amod | Enhanced,learning |
R4350 | T6438 | T6440 | nsubj | learning,was |
R4351 | T6439 | T6438 | compound | odor,learning |
R4352 | T6441 | T6438 | cc | and,learning |
R4353 | T6442 | T6438 | conj | discrimination,learning |
R4354 | T6443 | T6440 | punct | ", ",was |
R4355 | T6444 | T6440 | prep | on,was |
R4356 | T6445 | T6446 | det | the,hand |
R4357 | T6446 | T6444 | pobj | hand,on |
R4358 | T6447 | T6446 | amod | other,hand |
R4359 | T6448 | T6440 | punct | ", ",was |
R4360 | T6449 | T6440 | acomp | independent,was |
R4361 | T6450 | T6449 | prep | of,independent |
R4362 | T6451 | T6452 | amod | residual,levels |
R4363 | T6452 | T6450 | pobj | levels,of |
R4364 | T6453 | T6454 | compound | GluR,B |
R4365 | T6454 | T6452 | compound | B,levels |
R4366 | T6455 | T6454 | punct | -,B |
R4367 | T6456 | T6440 | prep | in,was |
R4368 | T6457 | T6458 | det | the,bulb |
R4369 | T6458 | T6456 | pobj | bulb,in |
R4370 | T6459 | T6458 | amod | olfactory,bulb |
R4371 | T6460 | T6458 | cc | and,bulb |
R4372 | T6461 | T6462 | amod | other,areas |
R4373 | T6462 | T6458 | conj | areas,bulb |
R4374 | T6463 | T6462 | compound | forebrain,areas |
R4375 | T6464 | T6440 | punct | ", ",was |
R4376 | T6465 | T6440 | advcl | indicating,was |
R4377 | T6466 | T6467 | mark | that,are |
R4378 | T6467 | T6465 | ccomp | are,indicating |
R4379 | T6468 | T6469 | amod | moderate,reductions |
R4380 | T6469 | T6467 | nsubj | reductions,are |
R4381 | T6470 | T6471 | compound | GluR,B |
R4382 | T6471 | T6469 | compound | B,reductions |
R4383 | T6472 | T6471 | punct | -,B |
R4384 | T6473 | T6467 | acomp | sufficient,are |
R4385 | T6474 | T6475 | aux | to,saturate |
R4386 | T6475 | T6473 | xcomp | saturate,sufficient |
R4387 | T6476 | T6477 | amod | enhanced,learning |
R4388 | T6477 | T6475 | dobj | learning,saturate |
R4389 | T6478 | T6477 | compound | odor,learning |
R4390 | T6479 | T6477 | cc | and,learning |
R4391 | T6480 | T6477 | conj | discrimination,learning |
R4392 | T6481 | T6440 | punct | .,was |
R4393 | T6483 | T6484 | advmod | Thus,be |
R4394 | T6485 | T6484 | punct | ", ",be |
R4395 | T6486 | T6487 | mark | although,mediated |
R4396 | T6487 | T6484 | advcl | mediated,be |
R4397 | T6488 | T6487 | nsubjpass | both,mediated |
R4398 | T6489 | T6487 | auxpass | are,mediated |
R4399 | T6490 | T6487 | agent | by,mediated |
R4400 | T6491 | T6490 | pobj | alterations,by |
R4401 | T6492 | T6491 | prep | in,alterations |
R4402 | T6493 | T6494 | det | the,subunit |
R4403 | T6494 | T6492 | pobj | subunit,in |
R4404 | T6495 | T6494 | compound | AMPAR,subunit |
R4405 | T6496 | T6497 | compound | GluR,B |
R4406 | T6497 | T6494 | appos | B,subunit |
R4407 | T6498 | T6497 | punct | -,B |
R4408 | T6499 | T6487 | punct | ", ",mediated |
R4409 | T6500 | T6487 | prep | due,mediated |
R4410 | T6501 | T6500 | pcomp | to,due |
R4411 | T6502 | T6503 | det | the,curves |
R4412 | T6503 | T6500 | pobj | curves,due |
R4413 | T6504 | T6505 | advmod | qualitatively,different |
R4414 | T6505 | T6503 | amod | different,curves |
R4415 | T6506 | T6507 | compound | dose,response |
R4416 | T6507 | T6503 | compound | response,curves |
R4417 | T6508 | T6507 | punct | -,response |
R4418 | T6509 | T6484 | punct | ", ",be |
R4419 | T6510 | T6511 | det | the,phenotypes |
R4420 | T6511 | T6484 | nsubj | phenotypes,be |
R4421 | T6512 | T6511 | prep | regarding,phenotypes |
R4422 | T6513 | T6514 | amod | olfactory,memory |
R4423 | T6514 | T6512 | pobj | memory,regarding |
R4424 | T6515 | T6514 | punct | ", ",memory |
R4425 | T6516 | T6514 | cc | and,memory |
R4426 | T6517 | T6518 | amod | olfactory,discrimination |
R4427 | T6518 | T6514 | conj | discrimination,memory |
R4428 | T6519 | T6518 | compound | learning,discrimination |
R4429 | T6520 | T6518 | punct | /,discrimination |
R4430 | T6521 | T6484 | aux | must,be |
R4431 | T6522 | T6523 | advmod | mechanistically,distinct |
R4432 | T6523 | T6484 | acomp | distinct,be |
R4433 | T6524 | T6484 | punct | .,be |