PMC:1208879 / 19731-20282 4 Projects
Annnotations
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T5479 | 0-6 | NN | denotes | TRIM11 |
| T5480 | 7-9 | VBZ | denotes | is |
| T5481 | 10-11 | DT | denotes | a |
| T5482 | 12-18 | NN | denotes | member |
| T5483 | 19-21 | IN | denotes | of |
| T5484 | 22-25 | DT | denotes | the |
| T5486 | 26-31 | NN | denotes | mouse |
| T5487 | 32-42 | JJ | denotes | tripartite |
| T5488 | 43-48 | NN | denotes | motif |
| T5489 | 49-56 | NN | denotes | protein |
| T5485 | 57-63 | NN | denotes | family |
| T5490 | 64-65 | -LRB- | denotes | ( |
| T5491 | 65-69 | RB | denotes | also |
| T5492 | 70-75 | VBN | denotes | known |
| T5493 | 76-78 | IN | denotes | as |
| T5494 | 79-82 | DT | denotes | the |
| T5496 | 83-87 | NN | denotes | RBCC |
| T5495 | 88-94 | NN | denotes | family |
| T5497 | 94-95 | -RRB- | denotes | ) |
| T5498 | 95-97 | , | denotes | , |
| T5499 | 97-100 | CC | denotes | and |
| T5500 | 101-109 | VBZ | denotes | contains |
| T5501 | 110-113 | DT | denotes | the |
| T5503 | 114-119 | CD | denotes | three |
| T5504 | 120-134 | JJ | denotes | characteristic |
| T5505 | 135-145 | JJ | denotes | structural |
| T5502 | 146-152 | NNS | denotes | motifs |
| T5506 | 153-155 | IN | denotes | of |
| T5507 | 156-160 | DT | denotes | this |
| T5509 | 161-168 | NN | denotes | protein |
| T5508 | 169-175 | NN | denotes | family |
| T5510 | 175-177 | , | denotes | , |
| T5511 | 177-178 | DT | denotes | a |
| T5513 | 179-183 | NN | denotes | RING |
| T5512 | 184-190 | NN | denotes | finger |
| T5514 | 190-192 | , | denotes | , |
| T5515 | 192-193 | DT | denotes | a |
| T5517 | 194-195 | NN | denotes | B |
| T5519 | 195-196 | HYPH | denotes | - |
| T5518 | 196-199 | NN | denotes | box |
| T5520 | 200-204 | NN | denotes | zinc |
| T5516 | 205-211 | NN | denotes | finger |
| T5521 | 211-213 | , | denotes | , |
| T5522 | 213-216 | CC | denotes | and |
| T5523 | 217-218 | DT | denotes | a |
| T5525 | 219-225 | VBN | denotes | coiled |
| T5526 | 226-230 | NN | denotes | coil |
| T5524 | 231-237 | NN | denotes | domain |
| T5527 | 237-239 | , | denotes | , |
| T5528 | 239-241 | RB | denotes | as |
| T5530 | 242-246 | RB | denotes | well |
| T5529 | 247-249 | IN | denotes | as |
| T5531 | 250-251 | DT | denotes | a |
| T5533 | 252-257 | NN | denotes | B30.2 |
| T5532 | 258-264 | NN | denotes | domain |
| T5534 | 265-269 | WDT | denotes | that |
| T5536 | 270-272 | VBZ | denotes | is |
| T5535 | 273-278 | VBN | denotes | found |
| T5537 | 279-281 | IN | denotes | in |
| T5538 | 282-286 | JJ | denotes | many |
| T5539 | 287-290 | CC | denotes | but |
| T5540 | 291-294 | RB | denotes | not |
| T5541 | 295-298 | DT | denotes | all |
| T5543 | 299-303 | NN | denotes | TRIM |
| T5542 | 304-312 | NN | denotes | proteins |
| T5544 | 313-314 | -LRB- | denotes | [ |
| T5545 | 314-316 | CD | denotes | 38 |
| T5546 | 316-317 | -RRB- | denotes | ] |
| T5547 | 317-318 | . | denotes | . |
| T5548 | 318-435 | sentence | denotes | TRIM11 interacts with Humanin, a protein that suppresses the neurotoxicity associated with Alzheimer's disease [46]. |
| T5549 | 319-325 | NN | denotes | TRIM11 |
| T5550 | 326-335 | VBZ | denotes | interacts |
| T5551 | 336-340 | IN | denotes | with |
| T5552 | 341-348 | NN | denotes | Humanin |
| T5553 | 348-350 | , | denotes | , |
| T5554 | 350-351 | DT | denotes | a |
| T5555 | 352-359 | NN | denotes | protein |
| T5556 | 360-364 | WDT | denotes | that |
| T5557 | 365-375 | VBZ | denotes | suppresses |
| T5558 | 376-379 | DT | denotes | the |
| T5559 | 380-393 | NN | denotes | neurotoxicity |
| T5560 | 394-404 | VBN | denotes | associated |
| T5561 | 405-409 | IN | denotes | with |
| T5562 | 410-419 | NNP | denotes | Alzheimer |
| T5564 | 419-421 | POS | denotes | 's |
| T5563 | 422-429 | NN | denotes | disease |
| T5565 | 430-431 | -LRB- | denotes | [ |
| T5566 | 431-433 | CD | denotes | 46 |
| T5567 | 433-434 | -RRB- | denotes | ] |
| T5568 | 434-435 | . | denotes | . |
| T5569 | 435-551 | sentence | denotes | TRIM11 lowers Humanin levels by a mechanism that appears to involve ubiqutin-mediated proteasomal degradation [46]. |
| T5570 | 436-442 | NN | denotes | TRIM11 |
| T5571 | 443-449 | VBZ | denotes | lowers |
| T5572 | 450-457 | NN | denotes | Humanin |
| T5573 | 458-464 | NNS | denotes | levels |
| T5574 | 465-467 | IN | denotes | by |
| T5575 | 468-469 | DT | denotes | a |
| T5576 | 470-479 | NN | denotes | mechanism |
| T5577 | 480-484 | WDT | denotes | that |
| T5578 | 485-492 | VBZ | denotes | appears |
| T5579 | 493-495 | TO | denotes | to |
| T5580 | 496-503 | VB | denotes | involve |
| T5581 | 504-512 | NN | denotes | ubiqutin |
| T5583 | 512-513 | HYPH | denotes | - |
| T5582 | 513-521 | VBN | denotes | mediated |
| T5585 | 522-533 | JJ | denotes | proteasomal |
| T5584 | 534-545 | NN | denotes | degradation |
| T5586 | 546-547 | -LRB- | denotes | [ |
| T5587 | 547-549 | CD | denotes | 46 |
| T5588 | 549-550 | -RRB- | denotes | ] |
| T5589 | 550-551 | . | denotes | . |
| R3157 | T5479 | T5480 | nsubj | TRIM11,is |
| R3158 | T5481 | T5482 | det | a,member |
| R3159 | T5482 | T5480 | attr | member,is |
| R3160 | T5483 | T5482 | prep | of,member |
| R3161 | T5484 | T5485 | det | the,family |
| R3162 | T5485 | T5483 | pobj | family,of |
| R3163 | T5486 | T5485 | nmod | mouse,family |
| R3164 | T5487 | T5488 | amod | tripartite,motif |
| R3165 | T5488 | T5485 | compound | motif,family |
| R3166 | T5489 | T5485 | compound | protein,family |
| R3167 | T5490 | T5485 | punct | (,family |
| R3168 | T5491 | T5492 | advmod | also,known |
| R3169 | T5492 | T5485 | acl | known,family |
| R3170 | T5493 | T5492 | prep | as,known |
| R3171 | T5494 | T5495 | det | the,family |
| R3172 | T5495 | T5493 | pobj | family,as |
| R3173 | T5496 | T5495 | compound | RBCC,family |
| R3174 | T5497 | T5480 | punct | ),is |
| R3175 | T5498 | T5480 | punct | ", ",is |
| R3176 | T5499 | T5480 | cc | and,is |
| R3177 | T5500 | T5480 | conj | contains,is |
| R3178 | T5501 | T5502 | det | the,motifs |
| R3179 | T5502 | T5500 | dobj | motifs,contains |
| R3180 | T5503 | T5502 | nummod | three,motifs |
| R3181 | T5504 | T5502 | amod | characteristic,motifs |
| R3182 | T5505 | T5502 | amod | structural,motifs |
| R3183 | T5506 | T5502 | prep | of,motifs |
| R3184 | T5507 | T5508 | det | this,family |
| R3185 | T5508 | T5506 | pobj | family,of |
| R3186 | T5509 | T5508 | compound | protein,family |
| R3187 | T5510 | T5502 | punct | ", ",motifs |
| R3188 | T5511 | T5512 | det | a,finger |
| R3189 | T5512 | T5502 | appos | finger,motifs |
| R3190 | T5513 | T5512 | compound | RING,finger |
| R3191 | T5514 | T5512 | punct | ", ",finger |
| R3192 | T5515 | T5516 | det | a,finger |
| R3193 | T5516 | T5512 | conj | finger,finger |
| R3194 | T5517 | T5518 | compound | B,box |
| R3195 | T5518 | T5516 | compound | box,finger |
| R3196 | T5519 | T5518 | punct | -,box |
| R3197 | T5520 | T5516 | compound | zinc,finger |
| R3198 | T5521 | T5516 | punct | ", ",finger |
| R3199 | T5522 | T5516 | cc | and,finger |
| R3200 | T5523 | T5524 | det | a,domain |
| R3201 | T5524 | T5516 | conj | domain,finger |
| R3202 | T5525 | T5526 | amod | coiled,coil |
| R3203 | T5526 | T5524 | compound | coil,domain |
| R3204 | T5527 | T5502 | punct | ", ",motifs |
| R3205 | T5528 | T5529 | advmod | as,as |
| R3206 | T5529 | T5502 | cc | as,motifs |
| R3207 | T5530 | T5529 | advmod | well,as |
| R3208 | T5531 | T5532 | det | a,domain |
| R3209 | T5532 | T5502 | conj | domain,motifs |
| R3210 | T5533 | T5532 | compound | B30.2,domain |
| R3211 | T5534 | T5535 | dep | that,found |
| R3212 | T5535 | T5532 | relcl | found,domain |
| R3213 | T5536 | T5535 | auxpass | is,found |
| R3214 | T5537 | T5535 | prep | in,found |
| R3215 | T5538 | T5537 | pobj | many,in |
| R3216 | T5539 | T5538 | cc | but,many |
| R3217 | T5540 | T5539 | neg | not,but |
| R3218 | T5541 | T5542 | nmod | all,proteins |
| R3219 | T5542 | T5538 | conj | proteins,many |
| R3220 | T5543 | T5542 | compound | TRIM,proteins |
| R3221 | T5544 | T5545 | punct | [,38 |
| R3222 | T5545 | T5500 | parataxis | 38,contains |
| R3223 | T5546 | T5545 | punct | ],38 |
| R3224 | T5547 | T5480 | punct | .,is |
| R3225 | T5549 | T5550 | nsubj | TRIM11,interacts |
| R3226 | T5551 | T5550 | prep | with,interacts |
| R3227 | T5552 | T5551 | pobj | Humanin,with |
| R3228 | T5553 | T5552 | punct | ", ",Humanin |
| R3229 | T5554 | T5555 | det | a,protein |
| R3230 | T5555 | T5552 | appos | protein,Humanin |
| R3231 | T5556 | T5557 | dep | that,suppresses |
| R3232 | T5557 | T5555 | relcl | suppresses,protein |
| R3233 | T5558 | T5559 | det | the,neurotoxicity |
| R3234 | T5559 | T5557 | dobj | neurotoxicity,suppresses |
| R3235 | T5560 | T5559 | acl | associated,neurotoxicity |
| R3236 | T5561 | T5560 | prep | with,associated |
| R3237 | T5562 | T5563 | poss | Alzheimer,disease |
| R3238 | T5563 | T5561 | pobj | disease,with |
| R3239 | T5564 | T5562 | case | 's,Alzheimer |
| R3240 | T5565 | T5566 | punct | [,46 |
| R3241 | T5566 | T5550 | parataxis | 46,interacts |
| R3242 | T5567 | T5566 | punct | ],46 |
| R3243 | T5568 | T5550 | punct | .,interacts |
| R3244 | T5570 | T5571 | nsubj | TRIM11,lowers |
| R3245 | T5572 | T5573 | compound | Humanin,levels |
| R3246 | T5573 | T5571 | dobj | levels,lowers |
| R3247 | T5574 | T5571 | prep | by,lowers |
| R3248 | T5575 | T5576 | det | a,mechanism |
| R3249 | T5576 | T5574 | pobj | mechanism,by |
| R3250 | T5577 | T5578 | dep | that,appears |
| R3251 | T5578 | T5576 | relcl | appears,mechanism |
| R3252 | T5579 | T5580 | aux | to,involve |
| R3253 | T5580 | T5578 | xcomp | involve,appears |
| R3254 | T5581 | T5582 | npadvmod | ubiqutin,mediated |
| R3255 | T5582 | T5584 | amod | mediated,degradation |
| R3256 | T5583 | T5582 | punct | -,mediated |
| R3257 | T5584 | T5580 | dobj | degradation,involve |
| R3258 | T5585 | T5584 | amod | proteasomal,degradation |
| R3259 | T5586 | T5587 | punct | [,46 |
| R3260 | T5587 | T5571 | parataxis | 46,lowers |
| R3261 | T5588 | T5587 | punct | ],46 |
| R3262 | T5589 | T5571 | punct | .,lowers |