PMC:1189074 / 2143-2889 JSONTXT 5 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T373 0-13 JJ denotes Mitochondrial
T375 14-15 NN denotes β
T376 15-16 HYPH denotes -
T374 16-25 NN denotes oxidation
T378 26-28 IN denotes of
T379 29-34 JJ denotes fatty
T380 35-40 NNS denotes acids
T377 41-49 VBZ denotes provides
T381 50-56 NN denotes energy
T382 56-58 , denotes ,
T383 58-68 RB denotes especially
T384 69-75 IN denotes during
T385 76-83 NN denotes fasting
T386 84-94 NNS denotes conditions
T387 94-95 . denotes .
T388 95-201 sentence denotes Fatty acid oxidation occurs in mitochondria and consists of a repeating circuit of four sequential steps.
T389 96-101 JJ denotes Fatty
T390 102-106 NN denotes acid
T391 107-116 NN denotes oxidation
T392 117-123 VBZ denotes occurs
T393 124-126 IN denotes in
T394 127-139 NNS denotes mitochondria
T395 140-143 CC denotes and
T396 144-152 VBZ denotes consists
T397 153-155 IN denotes of
T398 156-157 DT denotes a
T400 158-167 VBG denotes repeating
T399 168-175 NN denotes circuit
T401 176-178 IN denotes of
T402 179-183 CD denotes four
T404 184-194 JJ denotes sequential
T403 195-200 NNS denotes steps
T405 200-201 . denotes .
T406 201-285 sentence denotes There are four straight-chain acyl-CoA dehydrogenases involved in the initial step.
T407 202-207 EX denotes There
T408 208-211 VBP denotes are
T409 212-216 CD denotes four
T411 217-225 JJ denotes straight
T413 225-226 HYPH denotes -
T412 226-231 NN denotes chain
T414 232-236 NN denotes acyl
T416 236-237 HYPH denotes -
T415 237-240 NN denotes CoA
T410 241-255 NNS denotes dehydrogenases
T417 256-264 VBN denotes involved
T418 265-267 IN denotes in
T419 268-271 DT denotes the
T421 272-279 JJ denotes initial
T420 280-284 NN denotes step
T422 284-285 . denotes .
T423 285-507 sentence denotes Medium-chain acyl-CoA dehydrogenase (MCAD) (the mouse gene is Acadm, whereas the protein is MCAD), specifically, is responsible for catalyzing the dehydrogenation of medium-chain length (C6–C12) fatty acid thioesters [1].
T424 286-292 JJ denotes Medium
T426 292-293 HYPH denotes -
T425 293-298 NN denotes chain
T428 299-303 NN denotes acyl
T430 303-304 HYPH denotes -
T429 304-307 NN denotes CoA
T427 308-321 NN denotes dehydrogenase
T432 322-323 -LRB- denotes (
T433 323-327 NN denotes MCAD
T434 327-328 -RRB- denotes )
T435 329-330 -LRB- denotes (
T437 330-333 DT denotes the
T439 334-339 NN denotes mouse
T438 340-344 NN denotes gene
T436 345-347 VBZ denotes is
T440 348-353 NN denotes Acadm
T441 353-355 , denotes ,
T442 355-362 IN denotes whereas
T444 363-366 DT denotes the
T445 367-374 NN denotes protein
T443 375-377 VBZ denotes is
T446 378-382 NN denotes MCAD
T447 382-383 -RRB- denotes )
T448 383-385 , denotes ,
T449 385-397 RB denotes specifically
T450 397-399 , denotes ,
T431 399-401 VBZ denotes is
T451 402-413 JJ denotes responsible
T452 414-417 IN denotes for
T453 418-428 VBG denotes catalyzing
T454 429-432 DT denotes the
T455 433-448 NN denotes dehydrogenation
T456 449-451 IN denotes of
T457 452-458 JJ denotes medium
T459 458-459 HYPH denotes -
T458 459-464 NN denotes chain
T460 465-471 NN denotes length
T462 472-473 -LRB- denotes (
T464 473-475 NN denotes C6
T465 475-476 SYM denotes
T463 476-479 NN denotes C12
T466 479-480 -RRB- denotes )
T467 481-486 JJ denotes fatty
T468 487-491 NN denotes acid
T461 492-502 NNS denotes thioesters
T469 503-504 -LRB- denotes [
T470 504-505 CD denotes 1
T471 505-506 -RRB- denotes ]
T472 506-507 . denotes .
T473 507-625 sentence denotes Acadm is transcribed in the nucleus, translated in the cytosol, and translocated into the mitochondrial matrix [2–4].
T474 508-513 NN denotes Acadm
T476 514-516 VBZ denotes is
T475 517-528 VBN denotes transcribed
T477 529-531 IN denotes in
T478 532-535 DT denotes the
T479 536-543 NN denotes nucleus
T480 543-545 , denotes ,
T481 545-555 VBN denotes translated
T482 556-558 IN denotes in
T483 559-562 DT denotes the
T484 563-570 NN denotes cytosol
T485 570-572 , denotes ,
T486 572-575 CC denotes and
T487 576-588 VBN denotes translocated
T488 589-593 IN denotes into
T489 594-597 DT denotes the
T491 598-611 JJ denotes mitochondrial
T490 612-618 NN denotes matrix
T492 619-620 -LRB- denotes [
T493 620-621 CD denotes 2
T494 621-622 SYM denotes
T495 622-623 CD denotes 4
T496 623-624 -RRB- denotes ]
T497 624-625 . denotes .
T498 625-746 sentence denotes Once inside the mitochondrial matrix, the MCAD monomers are assembled into homotetramers to gain enzymatic activity [4].
T499 626-630 IN denotes Once
T500 631-637 IN denotes inside
T502 638-641 DT denotes the
T504 642-655 JJ denotes mitochondrial
T503 656-662 NN denotes matrix
T505 662-664 , denotes ,
T506 664-667 DT denotes the
T508 668-672 NN denotes MCAD
T507 673-681 NNS denotes monomers
T509 682-685 VBP denotes are
T501 686-695 VBN denotes assembled
T510 696-700 IN denotes into
T511 701-714 NNS denotes homotetramers
T512 715-717 TO denotes to
T513 718-722 VB denotes gain
T514 723-732 JJ denotes enzymatic
T515 733-741 NN denotes activity
T516 742-743 -LRB- denotes [
T517 743-744 CD denotes 4
T518 744-745 -RRB- denotes ]
T519 745-746 . denotes .
R181 T373 T374 amod Mitochondrial,oxidation
R182 T374 T377 nsubj oxidation,provides
R183 T375 T374 compound β,oxidation
R184 T376 T374 punct -,oxidation
R185 T378 T374 prep of,oxidation
R186 T379 T380 amod fatty,acids
R187 T380 T378 pobj acids,of
R188 T381 T377 dobj energy,provides
R189 T382 T377 punct ", ",provides
R190 T383 T384 advmod especially,during
R191 T384 T377 prep during,provides
R192 T385 T386 compound fasting,conditions
R193 T386 T384 pobj conditions,during
R194 T387 T377 punct .,provides
R195 T389 T390 amod Fatty,acid
R196 T390 T391 compound acid,oxidation
R197 T391 T392 nsubj oxidation,occurs
R198 T393 T392 prep in,occurs
R199 T394 T393 pobj mitochondria,in
R200 T395 T392 cc and,occurs
R201 T396 T392 conj consists,occurs
R202 T397 T396 prep of,consists
R203 T398 T399 det a,circuit
R204 T399 T397 pobj circuit,of
R205 T400 T399 amod repeating,circuit
R206 T401 T399 prep of,circuit
R207 T402 T403 nummod four,steps
R208 T403 T401 pobj steps,of
R209 T404 T403 amod sequential,steps
R210 T405 T392 punct .,occurs
R211 T407 T408 expl There,are
R212 T409 T410 nummod four,dehydrogenases
R213 T410 T408 attr dehydrogenases,are
R214 T411 T412 amod straight,chain
R215 T412 T410 compound chain,dehydrogenases
R216 T413 T412 punct -,chain
R217 T414 T415 compound acyl,CoA
R218 T415 T410 compound CoA,dehydrogenases
R219 T416 T415 punct -,CoA
R220 T417 T410 acl involved,dehydrogenases
R221 T418 T417 prep in,involved
R222 T419 T420 det the,step
R223 T420 T418 pobj step,in
R224 T421 T420 amod initial,step
R225 T422 T408 punct .,are
R226 T424 T425 amod Medium,chain
R227 T425 T427 compound chain,dehydrogenase
R228 T426 T425 punct -,chain
R229 T427 T431 nsubj dehydrogenase,is
R230 T428 T429 compound acyl,CoA
R231 T429 T427 compound CoA,dehydrogenase
R232 T430 T429 punct -,CoA
R233 T432 T427 punct (,dehydrogenase
R234 T433 T427 appos MCAD,dehydrogenase
R235 T434 T427 punct ),dehydrogenase
R236 T435 T436 punct (,is
R237 T436 T427 parataxis is,dehydrogenase
R238 T437 T438 det the,gene
R239 T438 T436 nsubj gene,is
R240 T439 T438 compound mouse,gene
R241 T440 T436 attr Acadm,is
R242 T441 T436 punct ", ",is
R243 T442 T443 mark whereas,is
R244 T443 T436 advcl is,is
R245 T444 T445 det the,protein
R246 T445 T443 nsubj protein,is
R247 T446 T443 attr MCAD,is
R248 T447 T436 punct ),is
R249 T448 T431 punct ", ",is
R250 T449 T431 advmod specifically,is
R251 T450 T431 punct ", ",is
R252 T451 T431 acomp responsible,is
R253 T452 T451 prep for,responsible
R254 T453 T452 pcomp catalyzing,for
R255 T454 T455 det the,dehydrogenation
R256 T455 T453 dobj dehydrogenation,catalyzing
R257 T456 T455 prep of,dehydrogenation
R258 T457 T458 amod medium,chain
R259 T458 T460 nmod chain,length
R260 T459 T458 punct -,chain
R261 T460 T461 nmod length,thioesters
R262 T461 T456 pobj thioesters,of
R263 T462 T463 punct (,C12
R264 T463 T460 parataxis C12,length
R265 T464 T463 nmod C6,C12
R266 T465 T463 punct –,C12
R267 T466 T463 punct ),C12
R268 T467 T468 amod fatty,acid
R269 T468 T461 compound acid,thioesters
R270 T469 T470 punct [,1
R271 T470 T431 parataxis 1,is
R272 T471 T470 punct ],1
R273 T472 T431 punct .,is
R274 T474 T475 nsubjpass Acadm,transcribed
R275 T476 T475 auxpass is,transcribed
R276 T477 T475 prep in,transcribed
R277 T478 T479 det the,nucleus
R278 T479 T477 pobj nucleus,in
R279 T480 T475 punct ", ",transcribed
R280 T481 T475 conj translated,transcribed
R281 T482 T481 prep in,translated
R282 T483 T484 det the,cytosol
R283 T484 T482 pobj cytosol,in
R284 T485 T481 punct ", ",translated
R285 T486 T481 cc and,translated
R286 T487 T481 conj translocated,translated
R287 T488 T487 prep into,translocated
R288 T489 T490 det the,matrix
R289 T490 T488 pobj matrix,into
R290 T491 T490 amod mitochondrial,matrix
R291 T492 T493 punct [,2
R292 T493 T487 parataxis 2,translocated
R293 T494 T495 punct –,4
R294 T495 T493 prep 4,2
R295 T496 T493 punct ],2
R296 T497 T475 punct .,transcribed
R297 T499 T500 mark Once,inside
R298 T500 T501 advcl inside,assembled
R299 T502 T503 det the,matrix
R300 T503 T500 pobj matrix,inside
R301 T504 T503 amod mitochondrial,matrix
R302 T505 T501 punct ", ",assembled
R303 T506 T507 det the,monomers
R304 T507 T501 nsubjpass monomers,assembled
R305 T508 T507 compound MCAD,monomers
R306 T509 T501 auxpass are,assembled
R307 T510 T501 prep into,assembled
R308 T511 T510 pobj homotetramers,into
R309 T512 T513 aux to,gain
R310 T513 T501 advcl gain,assembled
R311 T514 T515 amod enzymatic,activity
R312 T515 T513 dobj activity,gain
R313 T516 T517 punct [,4
R314 T517 T501 parataxis 4,assembled
R315 T518 T517 punct ],4
R316 T519 T501 punct .,assembled