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PMC:1189073 / 5289-5858 JSONTXT 5 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T2892 0-7 JJ denotes Several
T2894 8-13 NN denotes mouse
T2893 14-20 NNS denotes models
T2896 21-23 IN denotes of
T2897 24-32 NN denotes diabetes
T2898 33-42 NN denotes insipidus
T2899 43-47 VBP denotes have
T2900 48-52 VBN denotes been
T2895 53-62 VBN denotes generated
T2901 63-64 -LRB- denotes [
T2902 64-66 CD denotes 13
T2903 66-67 SYM denotes –
T2904 67-69 CD denotes 17
T2905 69-70 -RRB- denotes ]
T2906 70-71 . denotes .
T2907 71-179 sentence denotes In an attempt to recapitulate human NDI, mice have been generated with mutations in Aqp2 and Avpr2 [15,18].
T2908 72-74 IN denotes In
T2910 75-77 DT denotes an
T2911 78-85 NN denotes attempt
T2912 86-88 TO denotes to
T2913 89-101 VB denotes recapitulate
T2914 102-107 JJ denotes human
T2915 108-111 NN denotes NDI
T2916 111-113 , denotes ,
T2917 113-117 NNS denotes mice
T2918 118-122 VBP denotes have
T2919 123-127 VBN denotes been
T2909 128-137 VBN denotes generated
T2920 138-142 IN denotes with
T2921 143-152 NNS denotes mutations
T2922 153-155 IN denotes in
T2923 156-160 NN denotes Aqp2
T2924 161-164 CC denotes and
T2925 165-170 NN denotes Avpr2
T2926 171-172 -LRB- denotes [
T2928 172-174 CD denotes 15
T2929 174-175 , denotes ,
T2927 175-177 CD denotes 18
T2930 177-178 -RRB- denotes ]
T2931 178-179 . denotes .
T2932 179-264 sentence denotes Yang and colleagues created a mouse with a T126M knock-in mutation in the Aqp2 gene.
T2933 180-184 NNP denotes Yang
T2935 185-188 CC denotes and
T2936 189-199 NNS denotes colleagues
T2934 200-207 VBD denotes created
T2937 208-209 DT denotes a
T2938 210-215 NN denotes mouse
T2939 216-220 IN denotes with
T2940 221-222 DT denotes a
T2942 223-228 NN denotes T126M
T2943 229-234 VB denotes knock
T2944 234-235 HYPH denotes -
T2945 235-237 RP denotes in
T2941 238-246 NN denotes mutation
T2946 247-249 IN denotes in
T2947 250-253 DT denotes the
T2949 254-258 NN denotes Aqp2
T2948 259-263 NN denotes gene
T2950 263-264 . denotes .
T2951 264-330 sentence denotes Unexpectedly, homozygous mutant mice died within 6 d after birth.
T2952 265-277 RB denotes Unexpectedly
T2954 277-279 , denotes ,
T2955 279-289 JJ denotes homozygous
T2957 290-296 NN denotes mutant
T2956 297-301 NNS denotes mice
T2953 302-306 VBD denotes died
T2958 307-313 IN denotes within
T2959 314-315 CD denotes 6
T2960 316-317 NNS denotes d
T2961 318-323 IN denotes after
T2962 324-329 NN denotes birth
T2963 329-330 . denotes .
T2964 330-415 sentence denotes Interestingly, AVPR2-deficient male pups also die within the first week after birth.
T2965 331-344 RB denotes Interestingly
T2967 344-346 , denotes ,
T2968 346-351 NN denotes AVPR2
T2970 351-352 HYPH denotes -
T2969 352-361 JJ denotes deficient
T2972 362-366 JJ denotes male
T2971 367-371 NNS denotes pups
T2973 372-376 RB denotes also
T2966 377-380 VBP denotes die
T2974 381-387 IN denotes within
T2975 388-391 DT denotes the
T2977 392-397 JJ denotes first
T2976 398-402 NN denotes week
T2978 403-408 IN denotes after
T2979 409-414 NN denotes birth
T2980 414-415 . denotes .
T2981 415-569 sentence denotes Together these models suggest that the mouse may be a highly sensitive organism with regard to water homeostasis, and is unable to survive with polyuria.
T2982 416-424 RB denotes Together
T2984 425-430 DT denotes these
T2985 431-437 NNS denotes models
T2983 438-445 VBP denotes suggest
T2986 446-450 IN denotes that
T2988 451-454 DT denotes the
T2989 455-460 NN denotes mouse
T2990 461-464 MD denotes may
T2987 465-467 VB denotes be
T2991 468-469 DT denotes a
T2993 470-476 RB denotes highly
T2994 477-486 JJ denotes sensitive
T2992 487-495 NN denotes organism
T2995 496-500 IN denotes with
T2996 501-507 NN denotes regard
T2997 508-510 IN denotes to
T2998 511-516 NN denotes water
T2999 517-528 NN denotes homeostasis
T3000 528-530 , denotes ,
T3001 530-533 CC denotes and
T3002 534-536 VBZ denotes is
T3003 537-543 JJ denotes unable
T3004 544-546 TO denotes to
T3005 547-554 VB denotes survive
T3006 555-559 IN denotes with
T3007 560-568 NN denotes polyuria
T3008 568-569 . denotes .
R658 T2892 T2893 amod Several,models
R659 T2893 T2895 nsubjpass models,generated
R660 T2894 T2893 compound mouse,models
R661 T2896 T2893 prep of,models
R662 T2897 T2898 compound diabetes,insipidus
R663 T2898 T2896 pobj insipidus,of
R664 T2899 T2895 aux have,generated
R665 T2900 T2895 auxpass been,generated
R666 T2901 T2902 punct [,13
R667 T2902 T2895 parataxis 13,generated
R668 T2903 T2904 punct –,17
R669 T2904 T2902 prep 17,13
R670 T2905 T2902 punct ],13
R671 T2906 T2895 punct .,generated
R672 T2908 T2909 prep In,generated
R673 T2910 T2911 det an,attempt
R674 T2911 T2908 pobj attempt,In
R675 T2912 T2913 aux to,recapitulate
R676 T2913 T2911 acl recapitulate,attempt
R677 T2914 T2915 amod human,NDI
R678 T2915 T2913 dobj NDI,recapitulate
R679 T2916 T2909 punct ", ",generated
R680 T2917 T2909 nsubjpass mice,generated
R681 T2918 T2909 aux have,generated
R682 T2919 T2909 auxpass been,generated
R683 T2920 T2909 prep with,generated
R684 T2921 T2920 pobj mutations,with
R685 T2922 T2921 prep in,mutations
R686 T2923 T2922 pobj Aqp2,in
R687 T2924 T2923 cc and,Aqp2
R688 T2925 T2923 conj Avpr2,Aqp2
R689 T2926 T2927 punct [,18
R690 T2927 T2909 parataxis 18,generated
R691 T2928 T2927 nummod 15,18
R692 T2929 T2927 punct ",",18
R693 T2930 T2927 punct ],18
R694 T2931 T2909 punct .,generated
R695 T2933 T2934 nsubj Yang,created
R696 T2935 T2933 cc and,Yang
R697 T2936 T2933 conj colleagues,Yang
R698 T2937 T2938 det a,mouse
R699 T2938 T2934 dobj mouse,created
R700 T2939 T2938 prep with,mouse
R701 T2940 T2941 det a,mutation
R702 T2941 T2939 pobj mutation,with
R703 T2942 T2941 nmod T126M,mutation
R704 T2943 T2941 amod knock,mutation
R705 T2944 T2943 punct -,knock
R706 T2945 T2943 prt in,knock
R707 T2946 T2941 prep in,mutation
R708 T2947 T2948 det the,gene
R709 T2948 T2946 pobj gene,in
R710 T2949 T2948 compound Aqp2,gene
R711 T2950 T2934 punct .,created
R712 T2952 T2953 advmod Unexpectedly,died
R713 T2954 T2953 punct ", ",died
R714 T2955 T2956 amod homozygous,mice
R715 T2956 T2953 nsubj mice,died
R716 T2957 T2956 compound mutant,mice
R717 T2958 T2953 prep within,died
R718 T2959 T2960 nummod 6,d
R719 T2960 T2958 pobj d,within
R720 T2961 T2960 prep after,d
R721 T2962 T2961 pobj birth,after
R722 T2963 T2953 punct .,died
R723 T2965 T2966 advmod Interestingly,die
R724 T2967 T2966 punct ", ",die
R725 T2968 T2969 npadvmod AVPR2,deficient
R726 T2969 T2971 amod deficient,pups
R727 T2970 T2969 punct -,deficient
R728 T2971 T2966 nsubj pups,die
R729 T2972 T2971 amod male,pups
R730 T2973 T2966 advmod also,die
R731 T2974 T2966 prep within,die
R732 T2975 T2976 det the,week
R733 T2976 T2974 pobj week,within
R734 T2977 T2976 amod first,week
R735 T2978 T2976 prep after,week
R736 T2979 T2978 pobj birth,after
R737 T2980 T2966 punct .,die
R738 T2982 T2983 advmod Together,suggest
R739 T2984 T2985 det these,models
R740 T2985 T2983 nsubj models,suggest
R741 T2986 T2987 mark that,be
R742 T2987 T2983 ccomp be,suggest
R743 T2988 T2989 det the,mouse
R744 T2989 T2987 nsubj mouse,be
R746 T2990 T2987 aux may,be
R748 T2991 T2992 det a,organism
R749 T2992 T2987 attr organism,be
R751 T2993 T2994 advmod highly,sensitive
R752 T2994 T2992 amod sensitive,organism
R754 T2995 T2987 prep with,be
R755 T2996 T2995 pobj regard,with
R757 T2997 T2996 prep to,regard
R758 T2998 T2999 compound water,homeostasis
R759 T2999 T2997 pobj homeostasis,to
R760 T3000 T2987 punct ", ",be
R761 T3001 T2987 cc and,be
R763 T3002 T2987 conj is,be
R764 T3003 T3002 acomp unable,is
R765 T3004 T3005 aux to,survive
R767 T3005 T3003 xcomp survive,unable
R768 T3006 T3005 prep with,survive
R769 T3007 T3006 pobj polyuria,with
R771 T3008 T2983 punct .,suggest