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PMC:1189073 / 3091-4803 JSONTXT 5 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T2464 0-11 JJ denotes Nephrogenic
T2466 12-20 NN denotes diabetes
T2465 21-30 NN denotes insipidus
T2468 31-32 -LRB- denotes (
T2469 32-35 NN denotes NDI
T2470 35-36 -RRB- denotes )
T2467 37-39 VBZ denotes is
T2471 40-41 DT denotes a
T2472 42-49 NN denotes disease
T2473 50-63 VBN denotes characterized
T2474 64-66 IN denotes by
T2475 67-76 JJ denotes excessive
T2476 77-86 NN denotes urination
T2477 87-90 CC denotes and
T2478 91-97 RB denotes thirst
T2479 97-99 , denotes ,
T2480 99-106 IN denotes despite
T2481 107-113 JJ denotes normal
T2482 114-124 NN denotes production
T2483 125-127 IN denotes of
T2484 128-131 DT denotes the
T2486 132-144 JJ denotes antidiuretic
T2485 145-152 NN denotes hormone
T2487 153-161 NN denotes arginine
T2488 162-173 NN denotes vasopressin
T2489 174-175 -LRB- denotes (
T2490 175-178 NN denotes AVP
T2491 178-179 -RRB- denotes )
T2492 180-181 -LRB- denotes [
T2493 181-182 CD denotes 1
T2494 182-183 -RRB- denotes ]
T2495 183-184 . denotes .
T2496 184-327 sentence denotes The inherited forms are either X-linked as a consequence of mutation of the Avpr2 gene [2], or autosomal due to mutation of the Aqp2 gene [3].
T2497 185-188 DT denotes The
T2499 189-198 VBN denotes inherited
T2498 199-204 NNS denotes forms
T2500 205-208 VBP denotes are
T2501 209-215 RB denotes either
T2503 216-217 NN denotes X
T2504 217-218 HYPH denotes -
T2502 218-224 VBN denotes linked
T2505 225-227 IN denotes as
T2506 228-229 DT denotes a
T2507 230-241 NN denotes consequence
T2508 242-244 IN denotes of
T2509 245-253 NN denotes mutation
T2510 254-256 IN denotes of
T2511 257-260 DT denotes the
T2513 261-266 NN denotes Avpr2
T2512 267-271 NN denotes gene
T2514 272-273 -LRB- denotes [
T2515 273-274 CD denotes 2
T2516 274-275 -RRB- denotes ]
T2517 275-277 , denotes ,
T2518 277-279 CC denotes or
T2519 280-289 JJ denotes autosomal
T2520 290-293 JJ denotes due
T2521 294-296 IN denotes to
T2522 297-305 NN denotes mutation
T2523 306-308 IN denotes of
T2524 309-312 DT denotes the
T2526 313-317 NN denotes Aqp2
T2525 318-322 NN denotes gene
T2527 323-324 -LRB- denotes [
T2528 324-325 CD denotes 3
T2529 325-326 -RRB- denotes ]
T2530 326-327 . denotes .
T2531 327-491 sentence denotes Aquaporin-2 (AQP2) is a pore-forming protein belonging to a family of water channels [4], and it is expressed in collecting-duct principal cells in the kidney [5].
T2532 328-337 NN denotes Aquaporin
T2534 337-338 HYPH denotes -
T2535 338-339 CD denotes 2
T2536 340-341 -LRB- denotes (
T2537 341-345 NN denotes AQP2
T2538 345-346 -RRB- denotes )
T2533 347-349 VBZ denotes is
T2539 350-351 DT denotes a
T2541 352-356 NN denotes pore
T2543 356-357 HYPH denotes -
T2542 357-364 VBG denotes forming
T2540 365-372 NN denotes protein
T2544 373-382 VBG denotes belonging
T2545 383-385 IN denotes to
T2546 386-387 DT denotes a
T2547 388-394 NN denotes family
T2548 395-397 IN denotes of
T2549 398-403 NN denotes water
T2550 404-412 NNS denotes channels
T2551 413-414 -LRB- denotes [
T2552 414-415 CD denotes 4
T2553 415-416 -RRB- denotes ]
T2554 416-418 , denotes ,
T2555 418-421 CC denotes and
T2556 422-424 PRP denotes it
T2558 425-427 VBZ denotes is
T2557 428-437 VBN denotes expressed
T2559 438-440 IN denotes in
T2560 441-451 VBG denotes collecting
T2562 451-452 HYPH denotes -
T2561 452-456 NN denotes duct
T2564 457-466 JJ denotes principal
T2563 467-472 NNS denotes cells
T2565 473-475 IN denotes in
T2566 476-479 DT denotes the
T2567 480-486 NN denotes kidney
T2568 487-488 -LRB- denotes [
T2569 488-489 CD denotes 5
T2570 489-490 -RRB- denotes ]
T2571 490-491 . denotes .
T2572 491-700 sentence denotes Generally these proteins permit the passage of water through the plasma membrane (PM) of cells, several of which carry out this role specifically in the process of water reabsorption from urine in the kidney.
T2573 492-501 RB denotes Generally
T2575 502-507 DT denotes these
T2576 508-516 NN denotes proteins
T2574 517-523 VBP denotes permit
T2577 524-527 DT denotes the
T2578 528-535 NN denotes passage
T2579 536-538 IN denotes of
T2580 539-544 NN denotes water
T2581 545-552 IN denotes through
T2582 553-556 DT denotes the
T2584 557-563 NN denotes plasma
T2583 564-572 NN denotes membrane
T2585 573-574 -LRB- denotes (
T2586 574-576 NN denotes PM
T2587 576-577 -RRB- denotes )
T2588 578-580 IN denotes of
T2589 581-586 NNS denotes cells
T2590 586-588 , denotes ,
T2591 588-595 JJ denotes several
T2593 596-598 IN denotes of
T2594 599-604 WDT denotes which
T2592 605-610 VBP denotes carry
T2595 611-614 RP denotes out
T2596 615-619 DT denotes this
T2597 620-624 NN denotes role
T2598 625-637 RB denotes specifically
T2599 638-640 IN denotes in
T2600 641-644 DT denotes the
T2601 645-652 NN denotes process
T2602 653-655 IN denotes of
T2603 656-661 NN denotes water
T2604 662-674 NN denotes reabsorption
T2605 675-679 IN denotes from
T2606 680-685 NN denotes urine
T2607 686-688 IN denotes in
T2608 689-692 DT denotes the
T2609 693-699 NN denotes kidney
T2610 699-700 . denotes .
T2611 700-842 sentence denotes It has been established that aquaporins, although functional as a monomer, tetramerize before their insertion into the plasma membrane [4,6].
T2612 701-703 PRP denotes It
T2614 704-707 VBZ denotes has
T2615 708-712 VBN denotes been
T2613 713-724 VBN denotes established
T2616 725-729 IN denotes that
T2618 730-740 NNS denotes aquaporins
T2619 740-742 , denotes ,
T2620 742-750 IN denotes although
T2621 751-761 JJ denotes functional
T2622 762-764 IN denotes as
T2623 765-766 DT denotes a
T2624 767-774 NN denotes monomer
T2625 774-776 , denotes ,
T2617 776-787 VBP denotes tetramerize
T2626 788-794 IN denotes before
T2627 795-800 PRP$ denotes their
T2628 801-810 NN denotes insertion
T2629 811-815 IN denotes into
T2630 816-819 DT denotes the
T2632 820-826 NN denotes plasma
T2631 827-835 NN denotes membrane
T2633 836-837 -LRB- denotes [
T2635 837-838 CD denotes 4
T2636 838-839 , denotes ,
T2634 839-840 CD denotes 6
T2637 840-841 -RRB- denotes ]
T2638 841-842 . denotes .
T2639 842-1106 sentence denotes Furthermore these proteins can also be differentially targeted to distinct regions of the PM; for example, AQP2 is routed to the apical membrane of cells surrounding the collecting duct, whereas other aquaporins (AQP3 or 4) are inserted into the basolateral face.
T2640 843-854 RB denotes Furthermore
T2642 855-860 DT denotes these
T2643 861-869 NN denotes proteins
T2644 870-873 MD denotes can
T2645 874-878 RB denotes also
T2646 879-881 VB denotes be
T2647 882-896 RB denotes differentially
T2641 897-905 VBN denotes targeted
T2649 906-908 IN denotes to
T2650 909-917 JJ denotes distinct
T2651 918-925 NNS denotes regions
T2652 926-928 IN denotes of
T2653 929-932 DT denotes the
T2654 933-935 NN denotes PM
T2655 935-936 : denotes ;
T2656 937-940 IN denotes for
T2657 941-948 NN denotes example
T2658 948-950 , denotes ,
T2659 950-954 NN denotes AQP2
T2660 955-957 VBZ denotes is
T2648 958-964 VBN denotes routed
T2661 965-967 IN denotes to
T2662 968-971 DT denotes the
T2664 972-978 JJ denotes apical
T2663 979-987 NN denotes membrane
T2665 988-990 IN denotes of
T2666 991-996 NNS denotes cells
T2667 997-1008 VBG denotes surrounding
T2668 1009-1012 DT denotes the
T2670 1013-1023 VBG denotes collecting
T2669 1024-1028 NN denotes duct
T2671 1028-1030 , denotes ,
T2672 1030-1037 IN denotes whereas
T2674 1038-1043 JJ denotes other
T2675 1044-1054 NNS denotes aquaporins
T2676 1055-1056 -LRB- denotes (
T2677 1056-1060 NN denotes AQP3
T2678 1061-1063 CC denotes or
T2679 1064-1065 CD denotes 4
T2680 1065-1066 -RRB- denotes )
T2681 1067-1070 VBP denotes are
T2673 1071-1079 VBN denotes inserted
T2682 1080-1084 IN denotes into
T2683 1085-1088 DT denotes the
T2685 1089-1100 JJ denotes basolateral
T2684 1101-1105 NN denotes face
T2686 1105-1106 . denotes .
T2687 1106-1201 sentence denotes Unlike all other family members, AQP2 is not constitutively inserted into the plasma membrane.
T2688 1107-1113 IN denotes Unlike
T2690 1114-1117 DT denotes all
T2692 1118-1123 JJ denotes other
T2693 1124-1130 NN denotes family
T2691 1131-1138 NNS denotes members
T2694 1138-1140 , denotes ,
T2695 1140-1144 NN denotes AQP2
T2696 1145-1147 VBZ denotes is
T2697 1148-1151 RB denotes not
T2698 1152-1166 RB denotes constitutively
T2689 1167-1175 VBN denotes inserted
T2699 1176-1180 IN denotes into
T2700 1181-1184 DT denotes the
T2702 1185-1191 NN denotes plasma
T2701 1192-1200 NN denotes membrane
T2703 1200-1201 . denotes .
T2704 1201-1413 sentence denotes Under basal conditions, the protein resides in subapical intracellular vesicles; however, under conditions requiring water retention AQP2 translocates to the apical membrane, permitting water reabsorption [7,8].
T2705 1202-1207 IN denotes Under
T2707 1208-1213 JJ denotes basal
T2708 1214-1224 NNS denotes conditions
T2709 1224-1226 , denotes ,
T2710 1226-1229 DT denotes the
T2711 1230-1237 NN denotes protein
T2706 1238-1245 VBZ denotes resides
T2713 1246-1248 IN denotes in
T2714 1249-1258 JJ denotes subapical
T2716 1259-1272 JJ denotes intracellular
T2715 1273-1281 NNS denotes vesicles
T2717 1281-1282 : denotes ;
T2718 1283-1290 RB denotes however
T2719 1290-1292 , denotes ,
T2720 1292-1297 IN denotes under
T2721 1298-1308 NNS denotes conditions
T2722 1309-1318 VBG denotes requiring
T2723 1319-1324 NN denotes water
T2724 1325-1334 NN denotes retention
T2725 1335-1339 NN denotes AQP2
T2712 1340-1352 VBZ denotes translocates
T2726 1353-1355 IN denotes to
T2727 1356-1359 DT denotes the
T2729 1360-1366 JJ denotes apical
T2728 1367-1375 NN denotes membrane
T2730 1375-1377 , denotes ,
T2731 1377-1387 VBG denotes permitting
T2732 1388-1393 NN denotes water
T2733 1394-1406 NN denotes reabsorption
T2734 1407-1408 -LRB- denotes [
T2736 1408-1409 CD denotes 7
T2737 1409-1410 , denotes ,
T2735 1410-1411 CD denotes 8
T2738 1411-1412 -RRB- denotes ]
T2739 1412-1413 . denotes .
T2740 1413-1712 sentence denotes For this process to occur, AVP binds its receptor, AVPR2, on the basolateral face of the collecting duct cells, leading to a rise in intracellular cAMP, ultimately resulting in phosphorylation of AQP2 at serine 256 by cAMP-dependent protein kinase [9] and its redistribution to the plasma membrane.
T2741 1414-1417 IN denotes For
T2743 1418-1422 DT denotes this
T2744 1423-1430 NN denotes process
T2745 1431-1433 TO denotes to
T2742 1434-1439 VB denotes occur
T2747 1439-1441 , denotes ,
T2748 1441-1444 NN denotes AVP
T2746 1445-1450 VBZ denotes binds
T2749 1451-1454 PRP$ denotes its
T2750 1455-1463 NN denotes receptor
T2751 1463-1465 , denotes ,
T2752 1465-1470 NN denotes AVPR2
T2753 1470-1472 , denotes ,
T2754 1472-1474 IN denotes on
T2755 1475-1478 DT denotes the
T2757 1479-1490 JJ denotes basolateral
T2756 1491-1495 NN denotes face
T2758 1496-1498 IN denotes of
T2759 1499-1502 DT denotes the
T2761 1503-1513 VBG denotes collecting
T2762 1514-1518 NN denotes duct
T2760 1519-1524 NNS denotes cells
T2763 1524-1526 , denotes ,
T2764 1526-1533 VBG denotes leading
T2765 1534-1536 IN denotes to
T2766 1537-1538 DT denotes a
T2767 1539-1543 NN denotes rise
T2768 1544-1546 IN denotes in
T2769 1547-1560 JJ denotes intracellular
T2770 1561-1565 NN denotes cAMP
T2771 1565-1567 , denotes ,
T2772 1567-1577 RB denotes ultimately
T2773 1578-1587 VBG denotes resulting
T2774 1588-1590 IN denotes in
T2775 1591-1606 NN denotes phosphorylation
T2776 1607-1609 IN denotes of
T2777 1610-1614 NN denotes AQP2
T2778 1615-1617 IN denotes at
T2779 1618-1624 NN denotes serine
T2780 1625-1628 CD denotes 256
T2781 1629-1631 IN denotes by
T2782 1632-1636 NN denotes cAMP
T2784 1636-1637 HYPH denotes -
T2783 1637-1646 JJ denotes dependent
T2786 1647-1654 NN denotes protein
T2785 1655-1661 NN denotes kinase
T2787 1662-1663 -LRB- denotes [
T2788 1663-1664 CD denotes 9
T2789 1664-1665 -RRB- denotes ]
T2790 1666-1669 CC denotes and
T2791 1670-1673 PRP$ denotes its
T2792 1674-1688 NN denotes redistribution
T2793 1689-1691 IN denotes to
T2794 1692-1695 DT denotes the
T2796 1696-1702 NN denotes plasma
T2795 1703-1711 NN denotes membrane
T2797 1711-1712 . denotes .
R254 T2464 T2465 amod Nephrogenic,insipidus
R255 T2465 T2467 nsubj insipidus,is
R256 T2466 T2465 compound diabetes,insipidus
R257 T2468 T2465 punct (,insipidus
R258 T2469 T2465 appos NDI,insipidus
R259 T2470 T2467 punct ),is
R260 T2471 T2472 det a,disease
R261 T2472 T2467 attr disease,is
R262 T2473 T2472 acl characterized,disease
R263 T2474 T2473 agent by,characterized
R264 T2475 T2476 amod excessive,urination
R265 T2476 T2474 pobj urination,by
R266 T2477 T2476 cc and,urination
R267 T2478 T2476 conj thirst,urination
R268 T2479 T2473 punct ", ",characterized
R269 T2480 T2473 prep despite,characterized
R270 T2481 T2482 amod normal,production
R271 T2482 T2480 pobj production,despite
R272 T2483 T2482 prep of,production
R273 T2484 T2485 det the,hormone
R274 T2485 T2483 pobj hormone,of
R275 T2486 T2485 amod antidiuretic,hormone
R276 T2487 T2488 compound arginine,vasopressin
R277 T2488 T2485 appos vasopressin,hormone
R278 T2489 T2488 punct (,vasopressin
R279 T2490 T2488 appos AVP,vasopressin
R280 T2491 T2467 punct ),is
R281 T2492 T2493 punct [,1
R282 T2493 T2467 parataxis 1,is
R283 T2494 T2493 punct ],1
R284 T2495 T2467 punct .,is
R285 T2497 T2498 det The,forms
R286 T2498 T2500 nsubj forms,are
R287 T2499 T2498 amod inherited,forms
R288 T2501 T2502 advmod either,linked
R289 T2502 T2500 acomp linked,are
R290 T2503 T2502 npadvmod X,linked
R291 T2504 T2502 punct -,linked
R292 T2505 T2502 prep as,linked
R293 T2506 T2507 det a,consequence
R294 T2507 T2505 pobj consequence,as
R295 T2508 T2507 prep of,consequence
R296 T2509 T2508 pobj mutation,of
R297 T2510 T2509 prep of,mutation
R298 T2511 T2512 det the,gene
R299 T2512 T2510 pobj gene,of
R300 T2513 T2512 compound Avpr2,gene
R301 T2514 T2515 punct [,2
R302 T2515 T2502 parataxis 2,linked
R303 T2516 T2515 punct ],2
R304 T2517 T2502 punct ", ",linked
R305 T2518 T2502 cc or,linked
R306 T2519 T2502 conj autosomal,linked
R307 T2520 T2521 amod due,to
R308 T2521 T2519 prep to,autosomal
R309 T2522 T2521 pobj mutation,to
R310 T2523 T2522 prep of,mutation
R311 T2524 T2525 det the,gene
R312 T2525 T2523 pobj gene,of
R313 T2526 T2525 compound Aqp2,gene
R314 T2527 T2528 punct [,3
R315 T2528 T2519 parataxis 3,autosomal
R316 T2529 T2528 punct ],3
R317 T2530 T2500 punct .,are
R318 T2532 T2533 nsubj Aquaporin,is
R319 T2534 T2532 punct -,Aquaporin
R320 T2535 T2532 nummod 2,Aquaporin
R321 T2536 T2532 punct (,Aquaporin
R322 T2537 T2532 appos AQP2,Aquaporin
R323 T2538 T2533 punct ),is
R324 T2539 T2540 det a,protein
R325 T2540 T2533 attr protein,is
R326 T2541 T2542 npadvmod pore,forming
R327 T2542 T2540 amod forming,protein
R328 T2543 T2542 punct -,forming
R329 T2544 T2540 acl belonging,protein
R330 T2545 T2544 prep to,belonging
R331 T2546 T2547 det a,family
R332 T2547 T2545 pobj family,to
R333 T2548 T2547 prep of,family
R334 T2549 T2550 compound water,channels
R335 T2550 T2548 pobj channels,of
R336 T2551 T2552 punct [,4
R337 T2552 T2533 parataxis 4,is
R338 T2553 T2552 punct ],4
R339 T2554 T2533 punct ", ",is
R340 T2555 T2533 cc and,is
R341 T2556 T2557 nsubjpass it,expressed
R342 T2557 T2533 conj expressed,is
R343 T2558 T2557 auxpass is,expressed
R344 T2559 T2557 prep in,expressed
R345 T2560 T2561 amod collecting,duct
R346 T2561 T2563 nmod duct,cells
R347 T2562 T2561 punct -,duct
R348 T2563 T2559 pobj cells,in
R349 T2564 T2563 amod principal,cells
R350 T2565 T2557 prep in,expressed
R351 T2566 T2567 det the,kidney
R352 T2567 T2565 pobj kidney,in
R353 T2568 T2569 punct [,5
R354 T2569 T2557 parataxis 5,expressed
R355 T2570 T2569 punct ],5
R356 T2571 T2557 punct .,expressed
R357 T2573 T2574 advmod Generally,permit
R358 T2575 T2576 det these,proteins
R359 T2576 T2574 nsubj proteins,permit
R360 T2577 T2578 det the,passage
R361 T2578 T2574 dobj passage,permit
R362 T2579 T2578 prep of,passage
R363 T2580 T2579 pobj water,of
R364 T2581 T2578 prep through,passage
R365 T2582 T2583 det the,membrane
R366 T2583 T2581 pobj membrane,through
R367 T2584 T2583 compound plasma,membrane
R368 T2585 T2583 punct (,membrane
R369 T2586 T2583 appos PM,membrane
R370 T2587 T2583 punct ),membrane
R371 T2588 T2583 prep of,membrane
R372 T2589 T2588 pobj cells,of
R373 T2590 T2589 punct ", ",cells
R374 T2591 T2592 dep several,carry
R375 T2592 T2589 relcl carry,cells
R376 T2593 T2591 prep of,several
R377 T2594 T2593 pobj which,of
R378 T2595 T2592 prt out,carry
R379 T2596 T2597 det this,role
R380 T2597 T2592 dobj role,carry
R381 T2598 T2599 advmod specifically,in
R382 T2599 T2592 prep in,carry
R383 T2600 T2601 det the,process
R384 T2601 T2599 pobj process,in
R385 T2602 T2601 prep of,process
R386 T2603 T2604 compound water,reabsorption
R387 T2604 T2602 pobj reabsorption,of
R388 T2605 T2604 prep from,reabsorption
R389 T2606 T2605 pobj urine,from
R390 T2607 T2604 prep in,reabsorption
R391 T2608 T2609 det the,kidney
R392 T2609 T2607 pobj kidney,in
R393 T2610 T2574 punct .,permit
R394 T2612 T2613 nsubjpass It,established
R395 T2614 T2613 aux has,established
R396 T2615 T2613 auxpass been,established
R397 T2616 T2617 mark that,tetramerize
R398 T2617 T2613 ccomp tetramerize,established
R399 T2618 T2617 nsubj aquaporins,tetramerize
R400 T2619 T2617 punct ", ",tetramerize
R401 T2620 T2621 mark although,functional
R402 T2621 T2617 advcl functional,tetramerize
R403 T2622 T2621 prep as,functional
R404 T2623 T2624 det a,monomer
R405 T2624 T2622 pobj monomer,as
R406 T2625 T2617 punct ", ",tetramerize
R407 T2626 T2617 prep before,tetramerize
R408 T2627 T2628 poss their,insertion
R409 T2628 T2626 pobj insertion,before
R410 T2629 T2628 prep into,insertion
R411 T2630 T2631 det the,membrane
R412 T2631 T2629 pobj membrane,into
R413 T2632 T2631 compound plasma,membrane
R414 T2633 T2634 punct [,6
R415 T2634 T2613 parataxis 6,established
R416 T2635 T2634 nummod 4,6
R417 T2636 T2634 punct ",",6
R418 T2637 T2634 punct ],6
R419 T2638 T2613 punct .,established
R420 T2640 T2641 advmod Furthermore,targeted
R421 T2641 T2648 ccomp targeted,routed
R422 T2642 T2643 det these,proteins
R423 T2643 T2641 nsubjpass proteins,targeted
R424 T2644 T2641 aux can,targeted
R425 T2645 T2641 advmod also,targeted
R426 T2646 T2641 auxpass be,targeted
R427 T2647 T2641 advmod differentially,targeted
R428 T2649 T2641 prep to,targeted
R429 T2650 T2651 amod distinct,regions
R430 T2651 T2649 pobj regions,to
R431 T2652 T2651 prep of,regions
R432 T2653 T2654 det the,PM
R433 T2654 T2652 pobj PM,of
R434 T2655 T2648 punct ;,routed
R435 T2656 T2648 prep for,routed
R436 T2657 T2656 pobj example,for
R437 T2658 T2648 punct ", ",routed
R438 T2659 T2648 nsubjpass AQP2,routed
R439 T2660 T2648 auxpass is,routed
R440 T2661 T2648 prep to,routed
R441 T2662 T2663 det the,membrane
R442 T2663 T2661 pobj membrane,to
R443 T2664 T2663 amod apical,membrane
R444 T2665 T2663 prep of,membrane
R445 T2666 T2665 pobj cells,of
R446 T2667 T2666 acl surrounding,cells
R447 T2668 T2669 det the,duct
R448 T2669 T2667 dobj duct,surrounding
R449 T2670 T2669 amod collecting,duct
R450 T2671 T2648 punct ", ",routed
R451 T2672 T2673 mark whereas,inserted
R452 T2673 T2648 advcl inserted,routed
R453 T2674 T2675 amod other,aquaporins
R454 T2675 T2673 nsubjpass aquaporins,inserted
R455 T2676 T2675 punct (,aquaporins
R456 T2677 T2675 appos AQP3,aquaporins
R457 T2678 T2677 cc or,AQP3
R458 T2679 T2677 conj 4,AQP3
R459 T2680 T2673 punct ),inserted
R460 T2681 T2673 auxpass are,inserted
R461 T2682 T2673 prep into,inserted
R462 T2683 T2684 det the,face
R463 T2684 T2682 pobj face,into
R464 T2685 T2684 amod basolateral,face
R465 T2686 T2648 punct .,routed
R466 T2688 T2689 prep Unlike,inserted
R467 T2690 T2691 det all,members
R468 T2691 T2688 pobj members,Unlike
R469 T2692 T2691 amod other,members
R470 T2693 T2691 compound family,members
R471 T2694 T2689 punct ", ",inserted
R472 T2695 T2689 nsubjpass AQP2,inserted
R473 T2696 T2689 auxpass is,inserted
R474 T2697 T2689 neg not,inserted
R475 T2698 T2689 advmod constitutively,inserted
R476 T2699 T2689 prep into,inserted
R477 T2700 T2701 det the,membrane
R478 T2701 T2699 pobj membrane,into
R479 T2702 T2701 compound plasma,membrane
R480 T2703 T2689 punct .,inserted
R481 T2705 T2706 prep Under,resides
R482 T2706 T2712 ccomp resides,translocates
R483 T2707 T2708 amod basal,conditions
R484 T2708 T2705 pobj conditions,Under
R485 T2709 T2706 punct ", ",resides
R486 T2710 T2711 det the,protein
R487 T2711 T2706 nsubj protein,resides
R488 T2713 T2706 prep in,resides
R489 T2714 T2715 amod subapical,vesicles
R490 T2715 T2713 pobj vesicles,in
R491 T2716 T2715 amod intracellular,vesicles
R492 T2717 T2712 punct ;,translocates
R493 T2718 T2712 advmod however,translocates
R494 T2719 T2712 punct ", ",translocates
R495 T2720 T2712 prep under,translocates
R496 T2721 T2720 pobj conditions,under
R497 T2722 T2721 acl requiring,conditions
R498 T2723 T2724 compound water,retention
R499 T2724 T2722 dobj retention,requiring
R500 T2725 T2712 nsubj AQP2,translocates
R501 T2726 T2712 prep to,translocates
R502 T2727 T2728 det the,membrane
R503 T2728 T2726 pobj membrane,to
R504 T2729 T2728 amod apical,membrane
R505 T2730 T2712 punct ", ",translocates
R506 T2731 T2712 advcl permitting,translocates
R507 T2732 T2733 compound water,reabsorption
R508 T2733 T2731 dobj reabsorption,permitting
R509 T2734 T2735 punct [,8
R510 T2735 T2712 parataxis 8,translocates
R511 T2736 T2735 nummod 7,8
R512 T2737 T2735 punct ",",8
R513 T2738 T2735 punct ],8
R514 T2739 T2712 punct .,translocates
R515 T2741 T2742 mark For,occur
R516 T2742 T2746 advcl occur,binds
R517 T2743 T2744 det this,process
R518 T2744 T2742 nsubj process,occur
R519 T2745 T2742 aux to,occur
R520 T2747 T2746 punct ", ",binds
R521 T2748 T2746 nsubj AVP,binds
R522 T2749 T2750 poss its,receptor
R523 T2750 T2746 dobj receptor,binds
R524 T2751 T2750 punct ", ",receptor
R525 T2752 T2750 appos AVPR2,receptor
R526 T2753 T2746 punct ", ",binds
R527 T2754 T2746 prep on,binds
R528 T2755 T2756 det the,face
R529 T2756 T2754 pobj face,on
R530 T2757 T2756 amod basolateral,face
R531 T2758 T2756 prep of,face
R532 T2759 T2760 det the,cells
R533 T2760 T2758 pobj cells,of
R534 T2761 T2762 amod collecting,duct
R535 T2762 T2760 compound duct,cells
R536 T2763 T2746 punct ", ",binds
R537 T2764 T2746 advcl leading,binds
R538 T2765 T2764 prep to,leading
R539 T2766 T2767 det a,rise
R540 T2767 T2765 pobj rise,to
R541 T2768 T2767 prep in,rise
R542 T2769 T2770 amod intracellular,cAMP
R543 T2770 T2768 pobj cAMP,in
R544 T2771 T2764 punct ", ",leading
R545 T2772 T2773 advmod ultimately,resulting
R546 T2773 T2764 advcl resulting,leading
R547 T2774 T2773 prep in,resulting
R548 T2775 T2774 pobj phosphorylation,in
R549 T2776 T2775 prep of,phosphorylation
R550 T2777 T2776 pobj AQP2,of
R551 T2778 T2775 prep at,phosphorylation
R552 T2779 T2778 pobj serine,at
R553 T2780 T2779 nummod 256,serine
R554 T2781 T2775 prep by,phosphorylation
R555 T2782 T2783 npadvmod cAMP,dependent
R556 T2783 T2785 amod dependent,kinase
R557 T2784 T2783 punct -,dependent
R558 T2785 T2781 pobj kinase,by
R559 T2786 T2785 compound protein,kinase
R560 T2787 T2788 punct [,9
R561 T2788 T2775 parataxis 9,phosphorylation
R562 T2789 T2788 punct ],9
R563 T2790 T2775 cc and,phosphorylation
R564 T2791 T2792 poss its,redistribution
R565 T2792 T2775 conj redistribution,phosphorylation
R566 T2793 T2792 prep to,redistribution
R567 T2794 T2795 det the,membrane
R568 T2795 T2793 pobj membrane,to
R569 T2796 T2795 compound plasma,membrane
R570 T2797 T2746 punct .,binds