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PMC:1186732 / 50043-50803 JSONTXT 5 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T11446 0-2 IN denotes In
T11448 3-6 DT denotes the
T11450 7-14 JJ denotes present
T11449 15-20 NN denotes study
T11451 21-23 PRP denotes we
T11447 24-29 VBD denotes found
T11452 30-33 DT denotes the
T11454 34-39 NN denotes mouse
T11455 40-46 NNS denotes crumbs
T11453 47-55 NN denotes ortholog
T11457 56-58 TO denotes to
T11458 59-61 VB denotes be
T11459 62-64 RB denotes up
T11460 64-65 HYPH denotes -
T11456 65-74 VBN denotes regulated
T11461 75-77 IN denotes in
T11462 78-81 DT denotes the
T11464 82-85 NN denotes rd7
T11465 86-92 NN denotes mutant
T11463 93-99 NN denotes retina
T11466 100-102 IN denotes by
T11467 103-113 NN denotes microarray
T11468 113-115 , denotes ,
T11469 115-125 JJ denotes consistent
T11470 126-130 IN denotes with
T11471 131-134 PRP$ denotes its
T11473 135-141 JJR denotes higher
T11474 142-152 NN denotes expression
T11472 153-158 NN denotes level
T11475 159-161 IN denotes in
T11476 162-167 NNS denotes cones
T11477 168-172 IN denotes than
T11478 173-175 IN denotes in
T11479 176-180 NNS denotes rods
T11480 181-182 -LRB- denotes [
T11481 182-184 CD denotes 50
T11482 184-185 -RRB- denotes ]
T11483 185-186 . denotes .
T11484 186-419 sentence denotes Although we were unable to confirm this finding by in situ hybridization due to the weakness of the signal, it is possible that the up-regulation of crumbs in the retina is the cause of the lamination defects seen in the rd7 mutant.
T11485 187-195 IN denotes Although
T11487 196-198 PRP denotes we
T11486 199-203 VBD denotes were
T11489 204-210 JJ denotes unable
T11490 211-213 TO denotes to
T11491 214-221 VB denotes confirm
T11492 222-226 DT denotes this
T11493 227-234 NN denotes finding
T11494 235-237 IN denotes by
T11495 238-240 FW denotes in
T11496 241-245 FW denotes situ
T11497 246-259 NN denotes hybridization
T11498 260-263 IN denotes due
T11499 264-266 IN denotes to
T11500 267-270 DT denotes the
T11501 271-279 NN denotes weakness
T11502 280-282 IN denotes of
T11503 283-286 DT denotes the
T11504 287-293 NN denotes signal
T11505 293-295 , denotes ,
T11506 295-297 PRP denotes it
T11488 298-300 VBZ denotes is
T11507 301-309 JJ denotes possible
T11508 310-314 IN denotes that
T11510 315-318 DT denotes the
T11512 319-321 JJ denotes up
T11513 321-322 HYPH denotes -
T11511 322-332 NN denotes regulation
T11514 333-335 IN denotes of
T11515 336-342 NNS denotes crumbs
T11516 343-345 IN denotes in
T11517 346-349 DT denotes the
T11518 350-356 NN denotes retina
T11509 357-359 VBZ denotes is
T11519 360-363 DT denotes the
T11520 364-369 NN denotes cause
T11521 370-372 IN denotes of
T11522 373-376 DT denotes the
T11524 377-387 NN denotes lamination
T11523 388-395 NNS denotes defects
T11525 396-400 VBN denotes seen
T11526 401-403 IN denotes in
T11527 404-407 DT denotes the
T11529 408-411 NN denotes rd7
T11528 412-418 NN denotes mutant
T11530 418-419 . denotes .
T11531 419-652 sentence denotes Overexpression of wild-type crumbs in Drosophila has been shown to cause polarity defects leading to waviness of epithelia and even to misalignment of nuclei within photoreceptors analogous to what is seen in the rd7 retina [47,51].
T11532 420-434 NN denotes Overexpression
T11534 435-437 IN denotes of
T11535 438-442 JJ denotes wild
T11537 442-443 HYPH denotes -
T11536 443-447 NN denotes type
T11538 448-454 NNS denotes crumbs
T11539 455-457 IN denotes in
T11540 458-468 NNP denotes Drosophila
T11541 469-472 VBZ denotes has
T11542 473-477 VBN denotes been
T11533 478-483 VBN denotes shown
T11543 484-486 TO denotes to
T11544 487-492 VB denotes cause
T11545 493-501 NN denotes polarity
T11546 502-509 NNS denotes defects
T11547 510-517 VBG denotes leading
T11548 518-520 IN denotes to
T11549 521-529 NN denotes waviness
T11550 530-532 IN denotes of
T11551 533-542 NNS denotes epithelia
T11552 543-546 CC denotes and
T11553 547-551 RB denotes even
T11554 552-554 IN denotes to
T11555 555-567 NN denotes misalignment
T11556 568-570 IN denotes of
T11557 571-577 NNS denotes nuclei
T11558 578-584 IN denotes within
T11559 585-599 NNS denotes photoreceptors
T11560 600-609 JJ denotes analogous
T11561 610-612 IN denotes to
T11562 613-617 WP denotes what
T11564 618-620 VBZ denotes is
T11563 621-625 VBN denotes seen
T11565 626-628 IN denotes in
T11566 629-632 DT denotes the
T11568 633-636 NN denotes rd7
T11567 637-643 NN denotes retina
T11569 644-645 -LRB- denotes [
T11571 645-647 CD denotes 47
T11572 647-648 , denotes ,
T11570 648-650 CD denotes 51
T11573 650-651 -RRB- denotes ]
T11574 651-652 . denotes .
T11575 652-760 sentence denotes Future experiments will address this question by overexpressing full-length Crb1 in a wild-type background.
T11576 653-659 NN denotes Future
T11577 660-671 NNS denotes experiments
T11579 672-676 MD denotes will
T11578 677-684 VB denotes address
T11580 685-689 DT denotes this
T11581 690-698 NN denotes question
T11582 699-701 IN denotes by
T11583 702-716 VBG denotes overexpressing
T11584 717-721 JJ denotes full
T11586 721-722 HYPH denotes -
T11585 722-728 NN denotes length
T11587 729-733 NN denotes Crb1
T11588 734-736 IN denotes in
T11589 737-738 DT denotes a
T11591 739-743 JJ denotes wild
T11593 743-744 HYPH denotes -
T11592 744-748 NN denotes type
T11590 749-759 NN denotes background
T11594 759-760 . denotes .
R7434 T11504 T11502 pobj signal,of
R7436 T11505 T11488 punct ", ",is
R7437 T11506 T11488 nsubj it,is
R7438 T11507 T11488 acomp possible,is
R7439 T11508 T11509 mark that,is
R7441 T11509 T11488 ccomp is,is
R7442 T11510 T11511 det the,regulation
R7443 T11511 T11509 nsubj regulation,is
R7444 T11512 T11511 amod up,regulation
R7446 T11513 T11511 punct -,regulation
R7447 T11514 T11511 prep of,regulation
R7449 T11515 T11514 pobj crumbs,of
R7450 T11516 T11511 prep in,regulation
R7451 T11517 T11518 det the,retina
R7453 T11518 T11516 pobj retina,in
R7454 T11519 T11520 det the,cause
R7456 T11520 T11509 attr cause,is
R7457 T11521 T11520 prep of,cause
R7458 T11522 T11523 det the,defects
R7460 T11523 T11521 pobj defects,of
R7461 T11524 T11523 compound lamination,defects
R7463 T11525 T11523 acl seen,defects
R7464 T11526 T11525 prep in,seen
R7465 T11527 T11528 det the,mutant
R7467 T11528 T11526 pobj mutant,in
R7468 T11529 T11528 compound rd7,mutant
R7470 T11530 T11488 punct .,is
R7472 T11532 T11533 nsubjpass Overexpression,shown
R7473 T11534 T11532 prep of,Overexpression
R7475 T11535 T11536 amod wild,type
R7476 T11536 T11538 compound type,crumbs
R7477 T11537 T11536 punct -,type
R7478 T11538 T11534 pobj crumbs,of
R7479 T11539 T11532 prep in,Overexpression
R7481 T11540 T11539 pobj Drosophila,in
R7482 T11541 T11533 aux has,shown
R7483 T11542 T11533 auxpass been,shown
R7485 T11543 T11544 aux to,cause
R7486 T11544 T11533 xcomp cause,shown
R7487 T11545 T11546 compound polarity,defects
R7489 T11546 T11544 dobj defects,cause
R7490 T11547 T11546 acl leading,defects
R7492 T11548 T11547 prep to,leading
R7493 T11549 T11548 pobj waviness,to
R7495 T11550 T11549 prep of,waviness
R7496 T11551 T11550 pobj epithelia,of
R7497 T11552 T11548 cc and,to
R7499 T11553 T11554 advmod even,to
R7500 T11554 T11548 conj to,to
R7501 T11555 T11554 pobj misalignment,to
R7503 T11556 T11555 prep of,misalignment
R7504 T11557 T11556 pobj nuclei,of
R7505 T11558 T11555 prep within,misalignment
R7507 T11559 T11558 pobj photoreceptors,within
R7508 T11560 T11533 advcl analogous,shown
R7509 T11561 T11560 prep to,analogous
R7511 T11562 T11563 dep what,seen
R7514 T11563 T11561 pcomp seen,to
R7515 T11564 T11563 auxpass is,seen
R7516 T11565 T11563 prep in,seen
R7518 T11566 T11567 det the,retina
R7519 T11567 T11565 pobj retina,in
R7520 T11568 T11567 compound rd7,retina
R7522 T11569 T11570 punct [,51
R7523 T11570 T11533 parataxis 51,shown
R7525 T11571 T11570 nummod 47,51
R7526 T11572 T11570 punct ",",51
R7527 T11573 T11570 punct ],51
R7529 T11574 T11533 punct .,shown
R7530 T11576 T11577 compound Future,experiments
R7531 T11577 T11578 nsubj experiments,address
R7532 T11579 T11578 aux will,address
R7534 T11580 T11581 det this,question
R7535 T11581 T11578 dobj question,address
R7536 T11582 T11578 prep by,address
R7538 T11583 T11582 pcomp overexpressing,by
R7539 T11584 T11585 amod full,length
R7541 T11585 T11587 compound length,Crb1
R7542 T11586 T11585 punct -,length
R7543 T11587 T11583 dobj Crb1,overexpressing
R7545 T11588 T11583 prep in,overexpressing
R7546 T11589 T11590 det a,background
R7547 T11590 T11588 pobj background,in
R7549 T11591 T11592 amod wild,type
R7550 T11592 T11590 compound type,background
R7551 T11593 T11592 punct -,type
R7553 T11594 T11578 punct .,address
R7573 T11446 T11447 prep In,found
R7575 T11448 T11449 det the,study
R7579 T11449 T11446 pobj study,In
R7585 T11450 T11449 amod present,study
R7589 T11451 T11447 nsubj we,found
R7593 T11452 T11453 det the,ortholog
R7594 T11453 T11456 nsubjpass ortholog,regulated
R7595 T11454 T11453 compound mouse,ortholog
R7598 T11455 T11453 compound crumbs,ortholog
R7600 T11456 T11447 ccomp regulated,found
R7603 T11457 T11456 aux to,regulated
R7607 T11458 T11456 auxpass be,regulated
R7611 T11459 T11456 advmod up,regulated
R7615 T11460 T11456 punct -,regulated
R7619 T11461 T11456 prep in,regulated
R7622 T11462 T11463 det the,retina
R7626 T11463 T11461 pobj retina,in
R7628 T11464 T11463 compound rd7,retina
R7630 T11465 T11463 compound mutant,retina
R7632 T11466 T11456 prep by,regulated
R7638 T11467 T11466 pobj microarray,by
R7641 T11468 T11456 punct ", ",regulated
R7645 T11469 T11456 advcl consistent,regulated
R7649 T11470 T11469 prep with,consistent
R7652 T11471 T11472 poss its,level
R7656 T11472 T11470 pobj level,with
R7659 T11473 T11472 amod higher,level
R7663 T11474 T11472 compound expression,level
R7667 T11475 T11472 prep in,level
R7670 T11476 T11475 pobj cones,in
R7674 T11477 T11472 prep than,level
R7678 T11478 T11477 prep in,than
R7682 T11479 T11478 pobj rods,in
R7685 T11480 T11481 punct [,50
R7692 T11481 T11447 parataxis 50,found
R7696 T11482 T11481 punct ],50
R7700 T11483 T11447 punct .,found
R7703 T11485 T11486 mark Although,were
R7708 T11486 T11488 advcl were,is
R7711 T11487 T11486 nsubj we,were
R7713 T11489 T11486 acomp unable,were
R7714 T11490 T11491 aux to,confirm
R7717 T11491 T11489 xcomp confirm,unable
R7721 T11492 T11493 det this,finding
R7725 T11493 T11491 dobj finding,confirm
R7729 T11494 T11491 prep by,confirm
R7733 T11495 T11496 advmod in,situ
R7736 T11496 T11497 amod situ,hybridization
R7740 T11497 T11494 pobj hybridization,by
R7743 T11498 T11486 prep due,were
R7747 T11499 T11498 pcomp to,due
R7750 T11500 T11501 det the,weakness
R7754 T11501 T11498 pobj weakness,due
R7756 T11502 T11501 prep of,weakness
R7757 T11503 T11504 det the,signal