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PMC:1183529 / 26318-27349 JSONTXT 4 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T13928 0-3 PRP$ denotes Our
T13929 4-12 NN denotes analysis
T13931 13-15 IN denotes of
T13932 16-20 NNS denotes mice
T13933 21-29 VBG denotes carrying
T13934 30-39 NNS denotes mutations
T13935 40-42 IN denotes of
T13936 43-47 NN denotes Fog2
T13930 48-54 VBZ denotes proves
T13937 55-59 IN denotes that
T13939 60-65 EX denotes there
T13938 66-68 VBZ denotes is
T13940 69-70 DT denotes a
T13942 71-78 JJ denotes primary
T13941 79-85 NN denotes defect
T13943 86-88 IN denotes in
T13944 89-93 NN denotes lung
T13945 94-105 NN denotes development
T13946 106-110 WDT denotes that
T13947 111-118 VBZ denotes results
T13948 119-121 IN denotes in
T13949 122-130 JJ denotes specific
T13950 131-135 NN denotes loss
T13951 136-138 IN denotes of
T13952 139-142 DT denotes the
T13954 143-152 JJ denotes accessory
T13953 153-157 NN denotes lobe
T13955 158-161 CC denotes and
T13956 162-169 JJ denotes partial
T13957 170-174 NN denotes loss
T13958 175-177 IN denotes of
T13959 178-181 DT denotes the
T13961 182-187 JJ denotes right
T13962 188-194 JJ denotes middle
T13960 195-199 NN denotes lobe
T13963 199-200 . denotes .
T13964 200-303 sentence denotes The specific lobar defects prompted us to evaluate Fog2 expression at the time of early lobar budding.
T13965 201-204 DT denotes The
T13967 205-213 JJ denotes specific
T13968 214-219 NN denotes lobar
T13966 220-227 NNS denotes defects
T13969 228-236 VBD denotes prompted
T13970 237-239 PRP denotes us
T13971 240-242 TO denotes to
T13972 243-251 VB denotes evaluate
T13973 252-256 NN denotes Fog2
T13974 257-267 NN denotes expression
T13975 268-270 IN denotes at
T13976 271-274 DT denotes the
T13977 275-279 NN denotes time
T13978 280-282 IN denotes of
T13979 283-288 JJ denotes early
T13981 289-294 NN denotes lobar
T13980 295-302 NN denotes budding
T13982 302-303 . denotes .
T13983 303-536 sentence denotes While Fog2 expression is diffuse in the pulmonary mesenchyme after lobar structure is well established (E12.5), it is more focally expressed in the mesenchyme surrounding the right middle lobe and accessory buds as these lobes form.
T13984 304-309 IN denotes While
T13986 310-314 NN denotes Fog2
T13987 315-325 NN denotes expression
T13985 326-328 VBZ denotes is
T13989 329-336 JJ denotes diffuse
T13990 337-339 IN denotes in
T13991 340-343 DT denotes the
T13993 344-353 JJ denotes pulmonary
T13992 354-364 NN denotes mesenchyme
T13994 365-370 IN denotes after
T13996 371-376 NN denotes lobar
T13997 377-386 NN denotes structure
T13995 387-389 VBZ denotes is
T13998 390-394 RB denotes well
T13999 395-406 VBN denotes established
T14000 407-408 -LRB- denotes (
T14001 408-413 NN denotes E12.5
T14002 413-414 -RRB- denotes )
T14003 414-416 , denotes ,
T14004 416-418 PRP denotes it
T14005 419-421 VBZ denotes is
T14006 422-426 RBR denotes more
T14007 427-434 RB denotes focally
T13988 435-444 VBN denotes expressed
T14008 445-447 IN denotes in
T14009 448-451 DT denotes the
T14010 452-462 NN denotes mesenchyme
T14011 463-474 VBG denotes surrounding
T14012 475-478 DT denotes the
T14014 479-484 JJ denotes right
T14015 485-491 JJ denotes middle
T14013 492-496 NN denotes lobe
T14016 497-500 CC denotes and
T14017 501-510 JJ denotes accessory
T14018 511-515 NNS denotes buds
T14019 516-518 IN denotes as
T14021 519-524 DT denotes these
T14022 525-530 NNS denotes lobes
T14020 531-535 VBP denotes form
T14023 535-536 . denotes .
T14024 536-696 sentence denotes This matches the phenotype of right middle lobe and accessory lobe loss, and suggests that Fog2 has a specific patterning role in establishment of these lobes.
T14025 537-541 DT denotes This
T14026 542-549 VBZ denotes matches
T14027 550-553 DT denotes the
T14028 554-563 NN denotes phenotype
T14029 564-566 IN denotes of
T14030 567-572 JJ denotes right
T14032 573-579 JJ denotes middle
T14031 580-584 NN denotes lobe
T14034 585-588 CC denotes and
T14035 589-598 JJ denotes accessory
T14036 599-603 NN denotes lobe
T14033 604-608 NN denotes loss
T14037 608-610 , denotes ,
T14038 610-613 CC denotes and
T14039 614-622 VBZ denotes suggests
T14040 623-627 IN denotes that
T14042 628-632 NN denotes Fog2
T14041 633-636 VBZ denotes has
T14043 637-638 DT denotes a
T14045 639-647 JJ denotes specific
T14046 648-658 NN denotes patterning
T14044 659-663 NN denotes role
T14047 664-666 IN denotes in
T14048 667-680 NN denotes establishment
T14049 681-683 IN denotes of
T14050 684-689 DT denotes these
T14051 690-695 NNS denotes lobes
T14052 695-696 . denotes .
T14053 696-868 sentence denotes It is less clear whether loss of Fog2 results in a global branching defect, as Fog2 lungs appear to have a slight developmental delay, which could result from many causes.
T14054 697-699 PRP denotes It
T14055 700-702 VBZ denotes is
T14056 703-707 RBR denotes less
T14057 708-713 JJ denotes clear
T14058 714-721 IN denotes whether
T14060 722-726 NN denotes loss
T14061 727-729 IN denotes of
T14062 730-734 NN denotes Fog2
T14059 735-742 VBZ denotes results
T14063 743-745 IN denotes in
T14064 746-747 DT denotes a
T14066 748-754 JJ denotes global
T14067 755-764 NN denotes branching
T14065 765-771 NN denotes defect
T14068 771-773 , denotes ,
T14069 773-775 IN denotes as
T14071 776-780 NN denotes Fog2
T14072 781-786 NNS denotes lungs
T14070 787-793 VBP denotes appear
T14073 794-796 TO denotes to
T14074 797-801 VB denotes have
T14075 802-803 DT denotes a
T14077 804-810 JJ denotes slight
T14078 811-824 JJ denotes developmental
T14076 825-830 NN denotes delay
T14079 830-832 , denotes ,
T14080 832-837 WDT denotes which
T14082 838-843 MD denotes could
T14081 844-850 VB denotes result
T14083 851-855 IN denotes from
T14084 856-860 JJ denotes many
T14085 861-867 NNS denotes causes
T14086 867-868 . denotes .
T14087 868-1031 sentence denotes Cultured Fog2 lungs do develop an intricate branching pattern in the unaffected lobes that appears similar in the pattern to wild-type lungs after 5 d in culture.
T14088 869-877 VBN denotes Cultured
T14090 878-882 NN denotes Fog2
T14089 883-888 NNS denotes lungs
T14092 889-891 VBP denotes do
T14091 892-899 VB denotes develop
T14093 900-902 DT denotes an
T14095 903-912 JJ denotes intricate
T14096 913-922 NN denotes branching
T14094 923-930 NN denotes pattern
T14097 931-933 IN denotes in
T14098 934-937 DT denotes the
T14100 938-948 JJ denotes unaffected
T14099 949-954 NNS denotes lobes
T14101 955-959 WDT denotes that
T14102 960-967 VBZ denotes appears
T14103 968-975 JJ denotes similar
T14104 976-978 IN denotes in
T14105 979-982 DT denotes the
T14106 983-990 NN denotes pattern
T14107 991-993 IN denotes to
T14108 994-998 JJ denotes wild
T14110 998-999 HYPH denotes -
T14109 999-1003 NN denotes type
T14111 1004-1009 NNS denotes lungs
T14112 1010-1015 IN denotes after
T14113 1016-1017 CD denotes 5
T14114 1018-1019 NN denotes d
T14115 1020-1022 IN denotes in
T14116 1023-1030 NN denotes culture
T14117 1030-1031 . denotes .
R3785 T13928 T13929 poss Our,analysis
R3786 T13929 T13930 nsubj analysis,proves
R3788 T13931 T13929 prep of,analysis
R3789 T13932 T13931 pobj mice,of
R3791 T13933 T13932 acl carrying,mice
R3792 T13934 T13933 dobj mutations,carrying
R3793 T13935 T13934 prep of,mutations
R3795 T13936 T13935 pobj Fog2,of
R3796 T13937 T13938 mark that,is
R3797 T13938 T13930 ccomp is,proves
R3799 T13939 T13938 expl there,is
R3800 T13940 T13941 det a,defect
R3802 T13941 T13938 attr defect,is
R3803 T13942 T13941 amod primary,defect
R3804 T13943 T13941 prep in,defect
R3805 T13944 T13945 compound lung,development
R3807 T13945 T13943 pobj development,in
R3808 T13946 T13947 dep that,results
R3809 T13947 T13941 relcl results,defect
R3811 T13948 T13947 prep in,results
R3812 T13949 T13950 amod specific,loss
R3813 T13950 T13948 pobj loss,in
R3815 T13951 T13950 prep of,loss
R3816 T13952 T13953 det the,lobe
R3817 T13953 T13951 pobj lobe,of
R3819 T13954 T13953 amod accessory,lobe
R3820 T13955 T13950 cc and,loss
R3821 T13956 T13957 amod partial,loss
R3823 T13957 T13950 conj loss,loss
R3824 T13958 T13957 prep of,loss
R3825 T13959 T13960 det the,lobe
R3826 T13960 T13958 pobj lobe,of
R3827 T13961 T13960 amod right,lobe
R3829 T13962 T13960 amod middle,lobe
R3830 T13963 T13930 punct .,proves
R3832 T13965 T13966 det The,defects
R3833 T13966 T13969 nsubj defects,prompted
R3834 T13967 T13966 amod specific,defects
R3836 T13968 T13966 compound lobar,defects
R3837 T13970 T13969 dobj us,prompted
R3838 T13971 T13972 aux to,evaluate
R3840 T13972 T13969 xcomp evaluate,prompted
R3841 T13973 T13974 compound Fog2,expression
R3843 T13974 T13972 dobj expression,evaluate
R3844 T13975 T13972 prep at,evaluate
R3845 T13976 T13977 det the,time
R3847 T13977 T13975 pobj time,at
R3848 T13978 T13977 prep of,time
R3849 T13979 T13980 amod early,budding
R3851 T13980 T13978 pobj budding,of
R3853 T13981 T13980 compound lobar,budding
R3854 T13982 T13969 punct .,prompted
R3856 T13984 T13985 mark While,is
R3857 T13985 T13988 advcl is,expressed
R3858 T13986 T13987 compound Fog2,expression
R3860 T13987 T13985 nsubj expression,is
R3861 T13989 T13985 acomp diffuse,is
R3863 T13990 T13985 prep in,is
R3864 T13991 T13992 det the,mesenchyme
R3865 T13992 T13990 pobj mesenchyme,in
R3869 T13993 T13992 amod pulmonary,mesenchyme
R3870 T13994 T13995 mark after,is
R3872 T13995 T13985 advcl is,is
R3873 T13996 T13997 compound lobar,structure
R3875 T13997 T13995 nsubj structure,is
R3876 T13998 T13999 advmod well,established
R3877 T13999 T13995 acomp established,is
R3878 T14000 T14001 punct (,E12.5
R3879 T14001 T13995 parataxis E12.5,is
R3880 T14002 T14001 punct ),E12.5
R3882 T14003 T13988 punct ", ",expressed
R3883 T14004 T13988 nsubjpass it,expressed
R3884 T14005 T13988 auxpass is,expressed
R3886 T14006 T14007 advmod more,focally
R3887 T14007 T13988 advmod focally,expressed
R3888 T14008 T13988 prep in,expressed
R3890 T14009 T14010 det the,mesenchyme
R3893 T14010 T14008 pobj mesenchyme,in
R3894 T14011 T14010 acl surrounding,mesenchyme
R3896 T14012 T14013 det the,lobe
R3897 T14013 T14011 dobj lobe,surrounding
R3899 T14014 T14013 amod right,lobe
R3900 T14015 T14013 amod middle,lobe
R3901 T14016 T14013 cc and,lobe
R3903 T14017 T14018 amod accessory,buds
R3904 T14018 T14013 conj buds,lobe
R3905 T14019 T14020 mark as,form
R3907 T14020 T13988 advcl form,expressed
R3908 T14021 T14022 det these,lobes
R3910 T14022 T14020 nsubj lobes,form
R3911 T14023 T13988 punct .,expressed
R3913 T14025 T14026 nsubj This,matches
R3915 T14027 T14028 det the,phenotype
R3916 T14028 T14026 dobj phenotype,matches
R3917 T14029 T14028 prep of,phenotype
R3919 T14030 T14031 amod right,lobe
R3920 T14031 T14033 nmod lobe,loss
R3921 T14032 T14031 amod middle,lobe
R3923 T14033 T14029 pobj loss,of
R3924 T14034 T14031 cc and,lobe
R3925 T14035 T14036 amod accessory,lobe
R3927 T14036 T14031 conj lobe,lobe
R3928 T14037 T14026 punct ", ",matches
R3929 T14038 T14026 cc and,matches
R3930 T14039 T14026 conj suggests,matches
R3931 T14040 T14041 mark that,has
R3932 T14041 T14039 ccomp has,suggests
R3934 T14042 T14041 nsubj Fog2,has
R3935 T14043 T14044 det a,role
R3936 T14044 T14041 dobj role,has
R3938 T14045 T14044 amod specific,role
R3939 T14046 T14044 compound patterning,role
R3940 T14047 T14044 prep in,role
R3942 T14048 T14047 pobj establishment,in
R3943 T14049 T14048 prep of,establishment
R3944 T14050 T14051 det these,lobes
R3946 T14051 T14049 pobj lobes,of
R3947 T14052 T14026 punct .,matches
R3949 T14054 T14055 nsubj It,is
R3951 T14056 T14057 advmod less,clear
R3952 T14057 T14055 acomp clear,is
R3953 T14058 T14059 mark whether,results
R3955 T14059 T14055 ccomp results,is
R3956 T14060 T14059 nsubj loss,results
R3957 T14061 T14060 prep of,loss
R3959 T14062 T14061 pobj Fog2,of
R3960 T14063 T14059 prep in,results
R3962 T14064 T14065 det a,defect
R3964 T14065 T14063 pobj defect,in
R3966 T14066 T14065 amod global,defect
R3968 T14067 T14065 compound branching,defect
R3969 T14068 T14055 punct ", ",is
R3970 T14069 T14070 mark as,appear
R3972 T14070 T14055 advcl appear,is
R3973 T14071 T14072 compound Fog2,lungs
R3974 T14072 T14070 nsubj lungs,appear
R3976 T14073 T14074 aux to,have
R3977 T14074 T14070 xcomp have,appear
R3979 T14075 T14076 det a,delay
R3980 T14076 T14074 dobj delay,have
R3981 T14099 T14097 pobj lobes,in
R3982 T14077 T14076 amod slight,delay
R3983 T14078 T14076 amod developmental,delay
R3984 T14079 T14076 punct ", ",delay
R3985 T14080 T14081 dep which,result
R3986 T14081 T14076 relcl result,delay
R3987 T14082 T14081 aux could,result
R3988 T14083 T14081 prep from,result
R3989 T14100 T14099 amod unaffected,lobes
R3990 T14084 T14085 amod many,causes
R3991 T14085 T14083 pobj causes,from
R3992 T14086 T14055 punct .,is
R3993 T14101 T14102 dep that,appears
R3994 T14088 T14089 amod Cultured,lungs
R3995 T14089 T14091 nsubj lungs,develop
R3996 T14090 T14089 compound Fog2,lungs
R3997 T14102 T14094 relcl appears,pattern
R3998 T14092 T14091 aux do,develop
R3999 T14093 T14094 det an,pattern
R4000 T14103 T14102 oprd similar,appears
R4001 T14094 T14091 dobj pattern,develop
R4002 T14095 T14094 amod intricate,pattern
R4003 T14096 T14094 compound branching,pattern
R4004 T14104 T14103 prep in,similar
R4005 T14097 T14094 prep in,pattern
R4006 T14098 T14099 det the,lobes
R4007 T14105 T14106 det the,pattern
R4008 T14106 T14104 pobj pattern,in
R4009 T14107 T14103 prep to,similar
R4010 T14108 T14109 amod wild,type
R4012 T14109 T14111 compound type,lungs
R4015 T14110 T14109 punct -,type
R4019 T14111 T14107 pobj lungs,to
R4023 T14112 T14091 prep after,develop
R4027 T14113 T14114 nummod 5,d
R4031 T14114 T14112 pobj d,after
R4037 T14115 T14114 prep in,d
R4042 T14116 T14115 pobj culture,in
R4046 T14117 T14091 punct .,develop