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PMC:1140370 / 15159-15808 JSONTXT 4 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T4496 0-2 IN denotes In
T4498 3-6 NN denotes DNA
T4499 7-15 NN denotes helicase
T4500 16-22 NNS denotes assays
T4501 22-24 , denotes ,
T4502 24-28 NN denotes Mcm4
T4504 28-29 HYPH denotes /
T4505 29-30 CD denotes 6
T4506 30-31 HYPH denotes /
T4507 31-32 CD denotes 7
T4503 33-40 NN denotes complex
T4508 41-44 VBD denotes did
T4509 45-48 RB denotes not
T4497 49-53 VB denotes show
T4510 54-62 NN denotes helicase
T4511 63-71 NN denotes activity
T4512 72-74 IN denotes on
T4513 75-81 CC denotes either
T4514 82-85 NN denotes Bub
T4516 85-86 HYPH denotes -
T4517 86-88 CD denotes 10
T4518 89-91 CC denotes or
T4519 92-95 NN denotes Bub
T4520 95-96 HYPH denotes -
T4521 96-98 CD denotes 20
T4515 99-108 NN denotes substrate
T4522 108-109 . denotes .
T4523 109-226 sentence denotes The efficiency of displacement slightly improved as the length of the single-stranded segment increased up to 30 nt.
T4524 110-113 DT denotes The
T4525 114-124 NN denotes efficiency
T4527 125-127 IN denotes of
T4528 128-140 NN denotes displacement
T4529 141-149 RB denotes slightly
T4526 150-158 VBD denotes improved
T4530 159-161 IN denotes as
T4532 162-165 DT denotes the
T4533 166-172 NN denotes length
T4534 173-175 IN denotes of
T4535 176-179 DT denotes the
T4537 180-186 JJ denotes single
T4539 186-187 HYPH denotes -
T4538 187-195 VBN denotes stranded
T4536 196-203 NN denotes segment
T4531 204-213 VBD denotes increased
T4540 214-216 IN denotes up
T4542 217-219 IN denotes to
T4541 220-222 CD denotes 30
T4543 223-225 NN denotes nt
T4544 225-226 . denotes .
T4545 226-450 sentence denotes On Bub-T40 and Bub-T50, on the other hand, significant displacement was observed, indicating that a single-stranded segment of at least 40 nt long is required for efficient helicase actions on bubble substrates (Figure 2B).
T4546 227-229 IN denotes On
T4548 230-233 NN denotes Bub
T4550 233-234 HYPH denotes -
T4549 234-237 NN denotes T40
T4551 238-241 CC denotes and
T4552 242-245 NN denotes Bub
T4554 245-246 HYPH denotes -
T4553 246-249 NN denotes T50
T4555 249-251 , denotes ,
T4556 251-253 IN denotes on
T4557 254-257 DT denotes the
T4559 258-263 JJ denotes other
T4558 264-268 NN denotes hand
T4560 268-270 , denotes ,
T4561 270-281 JJ denotes significant
T4562 282-294 NN denotes displacement
T4563 295-298 VBD denotes was
T4547 299-307 VBN denotes observed
T4564 307-309 , denotes ,
T4565 309-319 VBG denotes indicating
T4566 320-324 IN denotes that
T4568 325-326 DT denotes a
T4570 327-333 JJ denotes single
T4572 333-334 HYPH denotes -
T4571 334-342 VBN denotes stranded
T4569 343-350 NN denotes segment
T4573 351-353 IN denotes of
T4574 354-356 RB denotes at
T4575 357-362 RBS denotes least
T4576 363-365 CD denotes 40
T4577 366-368 NN denotes nt
T4578 369-373 JJ denotes long
T4579 374-376 VBZ denotes is
T4567 377-385 VBN denotes required
T4580 386-389 IN denotes for
T4581 390-399 JJ denotes efficient
T4583 400-408 NN denotes helicase
T4582 409-416 NNS denotes actions
T4584 417-419 IN denotes on
T4585 420-426 NN denotes bubble
T4586 427-437 NNS denotes substrates
T4587 438-439 -LRB- denotes (
T4589 439-445 NN denotes Figure
T4588 446-448 NN denotes 2B
T4590 448-449 -RRB- denotes )
T4591 449-450 . denotes .
T4592 450-649 sentence denotes Taken together, the above results are consistent with the notion that the Mcm4/6/7 complex, loaded onto DNA as a double hexameric complex, efficiently unwinds the duplex region of the substrate DNA.
T4593 451-456 VBN denotes Taken
T4595 457-465 RB denotes together
T4596 465-467 , denotes ,
T4597 467-470 DT denotes the
T4599 471-476 JJ denotes above
T4598 477-484 NNS denotes results
T4594 485-488 VBP denotes are
T4600 489-499 JJ denotes consistent
T4601 500-504 IN denotes with
T4602 505-508 DT denotes the
T4603 509-515 NN denotes notion
T4604 516-520 IN denotes that
T4606 521-524 DT denotes the
T4608 525-529 NN denotes Mcm4
T4609 529-530 HYPH denotes /
T4610 530-531 CD denotes 6
T4611 531-532 HYPH denotes /
T4612 532-533 CD denotes 7
T4607 534-541 NN denotes complex
T4613 541-543 , denotes ,
T4614 543-549 VBN denotes loaded
T4615 550-554 IN denotes onto
T4616 555-558 NN denotes DNA
T4617 559-561 IN denotes as
T4618 562-563 DT denotes a
T4620 564-570 JJ denotes double
T4621 571-580 JJ denotes hexameric
T4619 581-588 NN denotes complex
T4622 588-590 , denotes ,
T4623 590-601 RB denotes efficiently
T4605 602-609 VBZ denotes unwinds
T4624 610-613 DT denotes the
T4626 614-620 NN denotes duplex
T4625 621-627 NN denotes region
T4627 628-630 IN denotes of
T4628 631-634 DT denotes the
T4630 635-644 NN denotes substrate
T4629 645-648 NN denotes DNA
T4631 648-649 . denotes .
R3014 T4496 T4497 prep In,show
R3015 T4498 T4499 compound DNA,helicase
R3016 T4499 T4500 compound helicase,assays
R3017 T4500 T4496 pobj assays,In
R3018 T4501 T4497 punct ", ",show
R3019 T4502 T4503 nmod Mcm4,complex
R3020 T4503 T4497 nsubj complex,show
R3021 T4504 T4502 punct /,Mcm4
R3022 T4505 T4502 nummod 6,Mcm4
R3023 T4506 T4502 punct /,Mcm4
R3024 T4507 T4502 nummod 7,Mcm4
R3025 T4508 T4497 aux did,show
R3026 T4509 T4497 neg not,show
R3027 T4510 T4511 compound helicase,activity
R3028 T4511 T4497 dobj activity,show
R3029 T4512 T4497 prep on,show
R3030 T4513 T4514 preconj either,Bub
R3031 T4514 T4515 nmod Bub,substrate
R3032 T4515 T4512 pobj substrate,on
R3033 T4516 T4514 punct -,Bub
R3034 T4517 T4514 nummod 10,Bub
R3035 T4518 T4514 cc or,Bub
R3036 T4519 T4514 conj Bub,Bub
R3037 T4520 T4519 punct -,Bub
R3038 T4521 T4519 nummod 20,Bub
R3039 T4522 T4497 punct .,show
R3040 T4524 T4525 det The,efficiency
R3041 T4525 T4526 nsubj efficiency,improved
R3042 T4527 T4525 prep of,efficiency
R3043 T4528 T4527 pobj displacement,of
R3044 T4529 T4526 advmod slightly,improved
R3045 T4530 T4531 mark as,increased
R3046 T4531 T4526 advcl increased,improved
R3047 T4532 T4533 det the,length
R3048 T4533 T4531 nsubj length,increased
R3049 T4534 T4533 prep of,length
R3050 T4535 T4536 det the,segment
R3051 T4536 T4534 pobj segment,of
R3052 T4537 T4538 amod single,stranded
R3053 T4538 T4536 amod stranded,segment
R3054 T4539 T4538 punct -,stranded
R3055 T4540 T4541 quantmod up,30
R3056 T4541 T4543 nummod 30,nt
R3057 T4542 T4541 quantmod to,30
R3058 T4543 T4531 npadvmod nt,increased
R3059 T4544 T4526 punct .,improved
R3060 T4546 T4547 prep On,observed
R3061 T4548 T4549 compound Bub,T40
R3062 T4549 T4546 pobj T40,On
R3063 T4550 T4549 punct -,T40
R3064 T4551 T4549 cc and,T40
R3065 T4552 T4553 compound Bub,T50
R3066 T4553 T4549 conj T50,T40
R3067 T4554 T4553 punct -,T50
R3068 T4555 T4547 punct ", ",observed
R3069 T4556 T4547 prep on,observed
R3070 T4557 T4558 det the,hand
R3071 T4558 T4556 pobj hand,on
R3072 T4559 T4558 amod other,hand
R3073 T4560 T4547 punct ", ",observed
R3074 T4561 T4562 amod significant,displacement
R3075 T4562 T4547 nsubjpass displacement,observed
R3076 T4563 T4547 auxpass was,observed
R3077 T4564 T4547 punct ", ",observed
R3078 T4565 T4547 advcl indicating,observed
R3079 T4566 T4567 mark that,required
R3080 T4567 T4565 ccomp required,indicating
R3081 T4568 T4569 det a,segment
R3082 T4569 T4567 nsubjpass segment,required
R3083 T4570 T4571 amod single,stranded
R3084 T4571 T4569 amod stranded,segment
R3085 T4572 T4571 punct -,stranded
R3086 T4573 T4569 prep of,segment
R3087 T4574 T4575 advmod at,least
R3088 T4575 T4576 advmod least,40
R3089 T4576 T4577 nummod 40,nt
R3090 T4577 T4573 pobj nt,of
R3091 T4578 T4577 amod long,nt
R3092 T4579 T4567 auxpass is,required
R3093 T4580 T4567 prep for,required
R3094 T4581 T4582 amod efficient,actions
R3095 T4582 T4580 pobj actions,for
R3096 T4583 T4582 compound helicase,actions
R3097 T4584 T4582 prep on,actions
R3098 T4585 T4586 compound bubble,substrates
R3099 T4586 T4584 pobj substrates,on
R3100 T4587 T4588 punct (,2B
R3101 T4588 T4567 parataxis 2B,required
R3102 T4589 T4588 compound Figure,2B
R3103 T4590 T4588 punct ),2B
R3104 T4591 T4547 punct .,observed
R3105 T4593 T4594 advcl Taken,are
R3106 T4595 T4593 advmod together,Taken
R3107 T4596 T4594 punct ", ",are
R3108 T4597 T4598 det the,results
R3109 T4598 T4594 nsubj results,are
R3110 T4599 T4598 amod above,results
R3111 T4600 T4594 acomp consistent,are
R3112 T4601 T4600 prep with,consistent
R3113 T4602 T4603 det the,notion
R3114 T4603 T4601 pobj notion,with
R3115 T4604 T4605 mark that,unwinds
R3116 T4605 T4603 acl unwinds,notion
R3117 T4606 T4607 det the,complex
R3118 T4607 T4605 nsubj complex,unwinds
R3119 T4608 T4607 nmod Mcm4,complex
R3120 T4609 T4608 punct /,Mcm4
R3121 T4610 T4608 nummod 6,Mcm4
R3122 T4611 T4608 punct /,Mcm4
R3123 T4612 T4608 nummod 7,Mcm4
R3124 T4613 T4607 punct ", ",complex
R3125 T4614 T4607 acl loaded,complex
R3126 T4615 T4614 prep onto,loaded
R3127 T4616 T4615 pobj DNA,onto
R3128 T4617 T4614 prep as,loaded
R3129 T4618 T4619 det a,complex
R3130 T4619 T4617 pobj complex,as
R3131 T4620 T4621 amod double,hexameric
R3132 T4621 T4619 amod hexameric,complex
R3133 T4622 T4605 punct ", ",unwinds
R3134 T4623 T4605 advmod efficiently,unwinds
R3135 T4624 T4625 det the,region
R3136 T4625 T4605 dobj region,unwinds
R3137 T4626 T4625 compound duplex,region
R3138 T4627 T4625 prep of,region
R3139 T4628 T4629 det the,DNA
R3140 T4629 T4627 pobj DNA,of
R3141 T4630 T4629 compound substrate,DNA
R3142 T4631 T4594 punct .,are