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PMC:1084331 / 26055-26974 JSONTXT 5 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function

Id Subject Object Predicate Lexical cue
T7754 0-2 PRP denotes We
T7756 3-7 RB denotes next
T7755 8-16 VBD denotes analyzed
T7757 17-24 IN denotes whether
T7759 25-32 NNS denotes changes
T7760 33-35 IN denotes in
T7761 36-39 DT denotes the
T7762 40-50 NN denotes expression
T7763 51-53 IN denotes of
T7764 54-62 NN denotes proteins
T7765 63-68 VBN denotes known
T7766 69-71 TO denotes to
T7768 72-74 VB denotes be
T7767 75-83 VBN denotes involved
T7769 84-86 IN denotes in
T7770 87-90 DT denotes the
T7771 91-101 NN denotes regulation
T7772 102-104 IN denotes of
T7773 105-113 JJ denotes neuronal
T7774 114-122 NN denotes survival
T7775 123-125 CC denotes or
T7776 126-130 NN denotes cell
T7777 131-136 NN denotes death
T7778 137-142 MD denotes could
T7779 143-145 VB denotes be
T7758 146-154 VBN denotes detected
T7780 155-157 IN denotes in
T7781 158-161 NN denotes DRG
T7782 162-164 IN denotes of
T7783 165-171 NN denotes TauEWS
T7785 171-172 HYPH denotes -
T7786 172-176 NN denotes Pea3
T7787 176-177 HYPH denotes /
T7788 177-178 SYM denotes +
T7784 179-186 NN denotes Isl1Cre
T7790 186-187 HYPH denotes /
T7791 187-188 SYM denotes +
T7789 189-196 NNS denotes embryos
T7792 196-197 . denotes .
T7793 197-387 sentence denotes We found no significant quantitative changes in the level of Akt/p-Akt or CREB/p-CREB in DRG (Figure 6O and 6P) both of which have been shown to be key regulators of neuronal survival [29].
T7794 198-200 PRP denotes We
T7795 201-206 VBD denotes found
T7796 207-209 DT denotes no
T7798 210-221 JJ denotes significant
T7799 222-234 JJ denotes quantitative
T7797 235-242 NNS denotes changes
T7800 243-245 IN denotes in
T7801 246-249 DT denotes the
T7802 250-255 NN denotes level
T7803 256-258 IN denotes of
T7804 259-262 NN denotes Akt
T7806 262-263 HYPH denotes /
T7807 263-264 NN denotes p
T7808 264-265 HYPH denotes -
T7805 265-268 NN denotes Akt
T7809 269-271 CC denotes or
T7810 272-276 NN denotes CREB
T7812 276-277 HYPH denotes /
T7813 277-278 NN denotes p
T7814 278-279 HYPH denotes -
T7811 279-283 NN denotes CREB
T7815 284-286 IN denotes in
T7816 287-290 NN denotes DRG
T7817 291-292 -LRB- denotes (
T7819 292-298 NN denotes Figure
T7818 299-301 NN denotes 6O
T7820 302-305 CC denotes and
T7821 306-308 NN denotes 6P
T7822 308-309 -RRB- denotes )
T7823 310-314 DT denotes both
T7825 315-317 IN denotes of
T7826 318-323 WDT denotes which
T7827 324-328 VBP denotes have
T7828 329-333 VBN denotes been
T7824 334-339 VBN denotes shown
T7829 340-342 TO denotes to
T7830 343-345 VB denotes be
T7831 346-349 JJ denotes key
T7832 350-360 NNS denotes regulators
T7833 361-363 IN denotes of
T7834 364-372 JJ denotes neuronal
T7835 373-381 NN denotes survival
T7836 382-383 -LRB- denotes [
T7837 383-385 CD denotes 29
T7838 385-386 -RRB- denotes ]
T7839 386-387 . denotes .
T7840 387-500 sentence denotes Moreover, the level of the proapoptotic Bcl2 family member Bax was not significantly reduced (Figure 6O and 6P).
T7841 388-396 RB denotes Moreover
T7843 396-398 , denotes ,
T7844 398-401 DT denotes the
T7845 402-407 NN denotes level
T7846 408-410 IN denotes of
T7847 411-414 DT denotes the
T7849 415-427 JJ denotes proapoptotic
T7850 428-432 NN denotes Bcl2
T7851 433-439 NN denotes family
T7852 440-446 NN denotes member
T7848 447-450 NN denotes Bax
T7853 451-454 VBD denotes was
T7854 455-458 RB denotes not
T7855 459-472 RB denotes significantly
T7842 473-480 VBN denotes reduced
T7856 481-482 -LRB- denotes (
T7858 482-488 NN denotes Figure
T7857 489-491 NN denotes 6O
T7859 492-495 CC denotes and
T7860 496-498 NN denotes 6P
T7861 498-499 -RRB- denotes )
T7862 499-500 . denotes .
T7863 500-919 sentence denotes In contrast, the expression level of the anti-apoptotic Bcl2 family members Bcl-xl and Bcl2 was significantly increased when compared to wild-type levels (Bcl2, 157%; Bcl-xl, 259%; average of n = 3 independent experiments; Figure 6O and 6P), providing a potential molecular explanation for the enhanced neuronal survival of DRG neurons of TauEWS-Pea3/+ Isl1Cre/+ embryos in the absence of Trk receptor expression [30].
T7864 501-503 IN denotes In
T7866 504-512 NN denotes contrast
T7867 512-514 , denotes ,
T7868 514-517 DT denotes the
T7870 518-528 NN denotes expression
T7869 529-534 NN denotes level
T7871 535-537 IN denotes of
T7872 538-541 DT denotes the
T7874 542-556 JJ denotes anti-apoptotic
T7875 557-561 NN denotes Bcl2
T7876 562-568 NN denotes family
T7873 569-576 NNS denotes members
T7877 577-580 NN denotes Bcl
T7879 580-581 HYPH denotes -
T7878 581-583 NN denotes xl
T7880 584-587 CC denotes and
T7881 588-592 NN denotes Bcl2
T7882 593-596 VBD denotes was
T7883 597-610 RB denotes significantly
T7865 611-620 VBN denotes increased
T7884 621-625 WRB denotes when
T7885 626-634 VBN denotes compared
T7886 635-637 IN denotes to
T7887 638-642 JJ denotes wild
T7889 642-643 HYPH denotes -
T7888 643-647 NN denotes type
T7890 648-654 NNS denotes levels
T7891 655-656 -LRB- denotes (
T7893 656-660 NN denotes Bcl2
T7895 660-662 , denotes ,
T7896 662-665 CD denotes 157
T7894 665-666 NN denotes %
T7897 666-667 : denotes ;
T7898 668-671 NN denotes Bcl
T7900 671-672 HYPH denotes -
T7899 672-674 NN denotes xl
T7902 674-676 , denotes ,
T7903 676-679 CD denotes 259
T7901 679-680 NN denotes %
T7904 680-681 : denotes ;
T7905 682-689 NN denotes average
T7906 690-692 IN denotes of
T7907 693-694 NN denotes n
T7909 695-696 SYM denotes =
T7910 697-698 CD denotes 3
T7911 699-710 JJ denotes independent
T7908 711-722 NNS denotes experiments
T7912 722-723 : denotes ;
T7913 724-730 NN denotes Figure
T7892 731-733 NN denotes 6O
T7914 734-737 CC denotes and
T7915 738-740 NN denotes 6P
T7916 740-741 -RRB- denotes )
T7917 741-743 , denotes ,
T7918 743-752 VBG denotes providing
T7919 753-754 DT denotes a
T7921 755-764 JJ denotes potential
T7922 765-774 JJ denotes molecular
T7920 775-786 NN denotes explanation
T7923 787-790 IN denotes for
T7924 791-794 DT denotes the
T7926 795-803 VBN denotes enhanced
T7927 804-812 JJ denotes neuronal
T7925 813-821 NN denotes survival
T7928 822-824 IN denotes of
T7929 825-828 NN denotes DRG
T7930 829-836 NNS denotes neurons
T7931 837-839 IN denotes of
T7932 840-846 NN denotes TauEWS
T7934 846-847 HYPH denotes -
T7935 847-851 NN denotes Pea3
T7936 851-852 HYPH denotes /
T7937 852-853 SYM denotes +
T7933 854-861 NN denotes Isl1Cre
T7939 861-862 HYPH denotes /
T7940 862-863 SYM denotes +
T7938 864-871 NNS denotes embryos
T7941 872-874 IN denotes in
T7942 875-878 DT denotes the
T7943 879-886 NN denotes absence
T7944 887-889 IN denotes of
T7945 890-893 NN denotes Trk
T7946 894-902 NN denotes receptor
T7947 903-913 NN denotes expression
T7948 914-915 -LRB- denotes [
T7949 915-917 CD denotes 30
T7950 917-918 -RRB- denotes ]
T7951 918-919 . denotes .
R3439 T7754 T7755 nsubj We,analyzed
R3441 T7756 T7755 advmod next,analyzed
R3442 T7757 T7758 mark whether,detected
R3444 T7758 T7755 ccomp detected,analyzed
R3445 T7759 T7758 nsubjpass changes,detected
R3446 T7760 T7759 prep in,changes
R3448 T7761 T7762 det the,expression
R3449 T7762 T7760 pobj expression,in
R3450 T7763 T7762 prep of,expression
R3452 T7764 T7763 pobj proteins,of
R3453 T7765 T7764 acl known,proteins
R3455 T7766 T7767 aux to,involved
R3456 T7767 T7765 xcomp involved,known
R3457 T7768 T7767 auxpass be,involved
R3459 T7769 T7767 prep in,involved
R3460 T7770 T7771 det the,regulation
R3461 T7771 T7769 pobj regulation,in
R3462 T7772 T7771 prep of,regulation
R3463 T7773 T7774 amod neuronal,survival
R3465 T7774 T7772 pobj survival,of
R3466 T7775 T7774 cc or,survival
R3467 T7776 T7777 compound cell,death
R3469 T7777 T7774 conj death,survival
R3470 T7778 T7758 aux could,detected
R3471 T7779 T7758 auxpass be,detected
R3473 T7780 T7758 prep in,detected
R3474 T7781 T7780 pobj DRG,in
R3475 T7782 T7781 prep of,DRG
R3477 T7783 T7784 nmod TauEWS,Isl1Cre
R3478 T7784 T7789 nmod Isl1Cre,embryos
R3480 T7785 T7784 punct -,Isl1Cre
R3481 T7786 T7784 nmod Pea3,Isl1Cre
R3482 T7787 T7784 punct /,Isl1Cre
R3484 T7788 T7784 punct +,Isl1Cre
R3485 T7789 T7782 pobj embryos,of
R3486 T7790 T7784 punct /,Isl1Cre
R3487 T7791 T7784 punct +,Isl1Cre
R3488 T7792 T7755 punct .,analyzed
R3490 T7794 T7795 nsubj We,found
R3491 T7796 T7797 det no,changes
R3493 T7797 T7795 dobj changes,found
R3494 T7798 T7797 amod significant,changes
R3495 T7799 T7797 amod quantitative,changes
R3497 T7800 T7797 prep in,changes
R3498 T7801 T7802 det the,level
R3501 T7802 T7800 pobj level,in
R3502 T7803 T7802 prep of,level
R3504 T7804 T7805 compound Akt,Akt
R3505 T7805 T7803 pobj Akt,of
R3506 T7806 T7805 punct /,Akt
R3508 T7807 T7805 compound p,Akt
R3509 T7808 T7805 punct -,Akt
R3510 T7809 T7805 cc or,Akt
R3512 T7810 T7811 compound CREB,CREB
R3513 T7811 T7805 conj CREB,Akt
R3515 T7812 T7811 punct /,CREB
R3516 T7813 T7811 compound p,CREB
R3518 T7814 T7811 punct -,CREB
R3519 T7815 T7802 prep in,level
R3520 T7816 T7815 pobj DRG,in
R3522 T7817 T7818 punct (,6O
R3523 T7818 T7816 parataxis 6O,DRG
R3525 T7819 T7818 compound Figure,6O
R3526 T7820 T7818 cc and,6O
R3527 T7821 T7818 conj 6P,6O
R3529 T7822 T7818 punct ),6O
R3530 T7823 T7824 dep both,shown
R3532 T7824 T7802 relcl shown,level
R3533 T7825 T7823 prep of,both
R3534 T7826 T7825 pobj which,of
R3536 T7827 T7824 aux have,shown
R3537 T7828 T7824 auxpass been,shown
R3538 T7829 T7830 aux to,be
R3539 T7830 T7824 xcomp be,shown
R3540 T7831 T7832 amod key,regulators
R3541 T7832 T7830 attr regulators,be
R3543 T7833 T7832 prep of,regulators
R3544 T7834 T7835 amod neuronal,survival
R3545 T7835 T7833 pobj survival,of
R3547 T7836 T7837 punct [,29
R3548 T7837 T7824 parataxis 29,shown
R3549 T7838 T7837 punct ],29
R3551 T7839 T7795 punct .,found
R3553 T7841 T7842 advmod Moreover,reduced
R3554 T7843 T7842 punct ", ",reduced
R3557 T7844 T7845 det the,level
R3558 T7845 T7842 nsubjpass level,reduced
R3560 T7846 T7845 prep of,level
R3561 T7847 T7848 det the,Bax
R3563 T7848 T7846 pobj Bax,of
R3564 T7849 T7848 amod proapoptotic,Bax
R3565 T7850 T7848 compound Bcl2,Bax
R3567 T7851 T7848 compound family,Bax
R3568 T7852 T7848 compound member,Bax
R3569 T7853 T7842 auxpass was,reduced
R3571 T7854 T7842 neg not,reduced
R3572 T7855 T7842 advmod significantly,reduced
R3577 T7856 T7857 punct (,6O
R3578 T7857 T7842 parataxis 6O,reduced
R3580 T7858 T7857 compound Figure,6O
R3581 T7859 T7857 cc and,6O
R3582 T7860 T7857 conj 6P,6O
R3584 T7861 T7857 punct ),6O
R3585 T7862 T7842 punct .,reduced
R3587 T7864 T7865 prep In,increased
R3589 T7866 T7864 pobj contrast,In
R3590 T7867 T7865 punct ", ",increased
R3591 T7868 T7869 det the,level
R3592 T7869 T7865 nsubjpass level,increased
R3593 T7870 T7869 compound expression,level
R3595 T7871 T7869 prep of,level
R3596 T7872 T7873 det the,members
R3597 T7873 T7871 pobj members,of
R3599 T7874 T7873 amod anti-apoptotic,members
R3600 T7875 T7873 compound Bcl2,members
R3601 T7876 T7873 compound family,members
R3603 T7877 T7878 compound Bcl,xl
R3604 T7878 T7873 appos xl,members
R3605 T7879 T7878 punct -,xl
R3607 T7880 T7878 cc and,xl
R3608 T7881 T7878 conj Bcl2,xl
R3609 T7882 T7865 auxpass was,increased
R3611 T7883 T7865 advmod significantly,increased
R3612 T7884 T7885 advmod when,compared
R3613 T7885 T7865 advcl compared,increased
R3615 T7886 T7885 prep to,compared
R3616 T7887 T7888 amod wild,type
R3617 T7888 T7890 compound type,levels
R3618 T7889 T7888 punct -,type
R3619 T7890 T7886 pobj levels,to
R3620 T7891 T7892 punct (,6O
R3621 T7892 T7890 parataxis 6O,levels
R3622 T7893 T7894 dep Bcl2,%
R3623 T7894 T7892 dep %,6O
R3624 T7895 T7894 punct ", ",%
R3625 T7896 T7894 nummod 157,%
R3626 T7897 T7892 punct ;,6O
R3627 T7898 T7899 compound Bcl,xl
R3628 T7899 T7901 dep xl,%
R3629 T7900 T7899 punct -,xl
R3630 T7901 T7892 dep %,6O
R3631 T7902 T7901 punct ", ",%
R3632 T7903 T7901 nummod 259,%
R3633 T7904 T7892 punct ;,6O
R3634 T7905 T7892 dep average,6O
R3635 T7906 T7905 prep of,average
R3636 T7907 T7908 nsubj n,experiments
R3637 T7908 T7906 pcomp experiments,of
R3638 T7909 T7908 punct =,experiments
R3639 T7910 T7908 nummod 3,experiments
R3640 T7911 T7908 amod independent,experiments
R3641 T7912 T7892 punct ;,6O
R3642 T7913 T7892 compound Figure,6O
R3643 T7914 T7892 cc and,6O
R3644 T7915 T7892 conj 6P,6O
R3645 T7916 T7892 punct ),6O
R3646 T7917 T7865 punct ", ",increased
R3647 T7918 T7865 advcl providing,increased
R3648 T7919 T7920 det a,explanation
R3649 T7920 T7918 dobj explanation,providing
R3650 T7921 T7920 amod potential,explanation
R3651 T7922 T7920 amod molecular,explanation
R3652 T7923 T7920 prep for,explanation
R3653 T7924 T7925 det the,survival
R3654 T7925 T7923 pobj survival,for
R3655 T7926 T7925 amod enhanced,survival
R3656 T7927 T7925 amod neuronal,survival
R3657 T7928 T7925 prep of,survival
R3658 T7929 T7930 compound DRG,neurons
R3659 T7930 T7928 pobj neurons,of
R3660 T7931 T7930 prep of,neurons
R3661 T7932 T7933 nmod TauEWS,Isl1Cre
R3662 T7933 T7938 nmod Isl1Cre,embryos
R3663 T7934 T7933 punct -,Isl1Cre
R3664 T7935 T7933 nmod Pea3,Isl1Cre
R3665 T7936 T7933 punct /,Isl1Cre
R3666 T7937 T7933 punct +,Isl1Cre
R3667 T7938 T7931 pobj embryos,of
R3668 T7939 T7933 punct /,Isl1Cre
R3669 T7940 T7933 punct +,Isl1Cre
R3670 T7941 T7925 prep in,survival
R3671 T7942 T7943 det the,absence
R3672 T7943 T7941 pobj absence,in
R3673 T7944 T7943 prep of,absence
R3674 T7945 T7946 compound Trk,receptor
R3675 T7946 T7947 compound receptor,expression
R3676 T7947 T7944 pobj expression,of
R3677 T7948 T7949 punct [,30
R3678 T7949 T7918 parataxis 30,providing
R3679 T7950 T7949 punct ],30
R3680 T7951 T7865 punct .,increased