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PMC:1064854 / 4925-5462 JSONTXT 7 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T4072 0-6 JJ denotes Recent
T4073 7-15 NN denotes evidence
T4075 16-20 RB denotes also
T4074 21-31 VBZ denotes implicates
T4076 32-35 NN denotes PGC
T4078 35-36 HYPH denotes -
T4077 36-38 NN denotes 1α
T4079 39-41 IN denotes in
T4080 42-45 DT denotes the
T4082 46-57 JJ denotes homeostatic
T4081 58-65 NN denotes control
T4083 66-68 IN denotes of
T4084 69-77 JJ denotes systemic
T4086 78-84 NN denotes energy
T4085 85-95 NN denotes metabolism
T4087 95-96 . denotes .
T4088 96-185 sentence denotes PGC-1α has been shown to regulate several key hepatic gluconeogenic genes [18,19,20,21].
T4089 97-100 NN denotes PGC
T4091 100-101 HYPH denotes -
T4090 101-103 NN denotes 1α
T4093 104-107 VBZ denotes has
T4094 108-112 VBN denotes been
T4092 113-118 VBN denotes shown
T4095 119-121 TO denotes to
T4096 122-130 VB denotes regulate
T4097 131-138 JJ denotes several
T4099 139-142 JJ denotes key
T4100 143-150 JJ denotes hepatic
T4101 151-164 JJ denotes gluconeogenic
T4098 165-170 NNS denotes genes
T4102 171-172 -LRB- denotes [
T4104 172-174 CD denotes 18
T4105 174-175 , denotes ,
T4106 175-177 CD denotes 19
T4107 177-178 , denotes ,
T4108 178-180 CD denotes 20
T4109 180-181 , denotes ,
T4103 181-183 CD denotes 21
T4110 183-184 -RRB- denotes ]
T4111 184-185 . denotes .
T4112 185-368 sentence denotes Recent studies have also shown altered expression of PGC-1α and downstream mitochondrial target pathways in skeletal muscle of humans with insulin resistance and diabetes [22,23,24].
T4113 186-192 JJ denotes Recent
T4114 193-200 NNS denotes studies
T4116 201-205 VBP denotes have
T4117 206-210 RB denotes also
T4115 211-216 VBN denotes shown
T4118 217-224 VBN denotes altered
T4119 225-235 NN denotes expression
T4120 236-238 IN denotes of
T4121 239-242 NN denotes PGC
T4123 242-243 HYPH denotes -
T4122 243-245 NN denotes 1α
T4125 246-249 CC denotes and
T4126 250-260 JJ denotes downstream
T4127 261-274 JJ denotes mitochondrial
T4128 275-281 NN denotes target
T4124 282-290 NNS denotes pathways
T4129 291-293 IN denotes in
T4130 294-302 JJ denotes skeletal
T4131 303-309 NN denotes muscle
T4132 310-312 IN denotes of
T4133 313-319 NNS denotes humans
T4134 320-324 IN denotes with
T4135 325-332 NN denotes insulin
T4136 333-343 NN denotes resistance
T4137 344-347 CC denotes and
T4138 348-356 NN denotes diabetes
T4139 357-358 -LRB- denotes [
T4141 358-360 CD denotes 22
T4142 360-361 , denotes ,
T4143 361-363 CD denotes 23
T4144 363-364 , denotes ,
T4140 364-366 CD denotes 24
T4145 366-367 -RRB- denotes ]
T4146 367-368 . denotes .
T4147 368-537 sentence denotes In addition, single nucleotide polymorphisms within the human PGC-1α gene have been shown to be associated with obesity, hypertension, and diabetes [25,26,27,28,29,30].
T4148 369-371 IN denotes In
T4150 372-380 NN denotes addition
T4151 380-382 , denotes ,
T4152 382-388 JJ denotes single
T4153 389-399 NN denotes nucleotide
T4154 400-413 NNS denotes polymorphisms
T4155 414-420 IN denotes within
T4156 421-424 DT denotes the
T4158 425-430 JJ denotes human
T4159 431-434 NN denotes PGC
T4161 434-435 HYPH denotes -
T4160 435-437 NN denotes 1α
T4157 438-442 NN denotes gene
T4162 443-447 VBP denotes have
T4163 448-452 VBN denotes been
T4149 453-458 VBN denotes shown
T4164 459-461 TO denotes to
T4166 462-464 VB denotes be
T4165 465-475 VBN denotes associated
T4167 476-480 IN denotes with
T4168 481-488 NN denotes obesity
T4169 488-490 , denotes ,
T4170 490-502 NN denotes hypertension
T4171 502-504 , denotes ,
T4172 504-507 CC denotes and
T4173 508-516 NN denotes diabetes
T4174 517-518 -LRB- denotes [
T4176 518-520 CD denotes 25
T4177 520-521 , denotes ,
T4178 521-523 CD denotes 26
T4179 523-524 , denotes ,
T4180 524-526 CD denotes 27
T4181 526-527 , denotes ,
T4182 527-529 CD denotes 28
T4183 529-530 , denotes ,
T4184 530-532 CD denotes 29
T4185 532-533 , denotes ,
T4175 533-535 CD denotes 30
T4186 535-536 -RRB- denotes ]
T4187 536-537 . denotes .
R777 T4072 T4073 amod Recent,evidence
R779 T4073 T4074 nsubj evidence,implicates
R780 T4075 T4074 advmod also,implicates
R782 T4076 T4077 compound PGC,1α
R783 T4077 T4074 dobj 1α,implicates
R784 T4078 T4077 punct -,1α
R786 T4079 T4074 prep in,implicates
R787 T4080 T4081 det the,control
R789 T4081 T4079 pobj control,in
R790 T4082 T4081 amod homeostatic,control
R791 T4083 T4081 prep of,control
R793 T4084 T4085 amod systemic,metabolism
R794 T4085 T4083 pobj metabolism,of
R795 T4086 T4085 compound energy,metabolism
R797 T4087 T4074 punct .,implicates
R798 T4089 T4090 compound PGC,1α
R800 T4090 T4092 nsubjpass 1α,shown
R801 T4091 T4090 punct -,1α
R803 T4093 T4092 aux has,shown
R805 T4094 T4092 auxpass been,shown
R806 T4095 T4096 aux to,regulate
R807 T4096 T4092 xcomp regulate,shown
R808 T4097 T4098 amod several,genes
R810 T4098 T4096 dobj genes,regulate
R811 T4099 T4098 amod key,genes
R812 T4100 T4098 amod hepatic,genes
R814 T4101 T4098 amod gluconeogenic,genes
R815 T4102 T4103 punct [,21
R817 T4103 T4092 parataxis 21,shown
R818 T4104 T4103 nummod 18,21
R819 T4105 T4103 punct ",",21
R821 T4106 T4103 nummod 19,21
R822 T4107 T4103 punct ",",21
R823 T4108 T4103 nummod 20,21
R824 T4109 T4103 punct ",",21
R825 T4110 T4103 punct ],21
R826 T4111 T4092 punct .,shown
R828 T4113 T4114 amod Recent,studies
R829 T4114 T4115 nsubj studies,shown
R831 T4116 T4115 aux have,shown
R832 T4117 T4115 advmod also,shown
R833 T4118 T4119 amod altered,expression
R835 T4119 T4115 dobj expression,shown
R836 T4120 T4119 prep of,expression
R837 T4121 T4122 nmod PGC,1α
R839 T4122 T4124 nmod 1α,pathways
R840 T4123 T4122 punct -,1α
R841 T4124 T4120 pobj pathways,of
R843 T4125 T4122 cc and,1α
R844 T4126 T4127 amod downstream,mitochondrial
R845 T4127 T4122 conj mitochondrial,1α
R847 T4128 T4124 compound target,pathways
R848 T4129 T4115 prep in,shown
R850 T4130 T4131 amod skeletal,muscle
R851 T4131 T4129 pobj muscle,in
R853 T4132 T4131 prep of,muscle
R854 T4133 T4132 pobj humans,of
R855 T4134 T4133 prep with,humans
R857 T4135 T4136 compound insulin,resistance
R858 T4136 T4134 pobj resistance,with
R860 T4137 T4136 cc and,resistance
R861 T4138 T4136 conj diabetes,resistance
R863 T4139 T4140 punct [,24
R864 T4140 T4115 parataxis 24,shown
R865 T4141 T4140 nummod 22,24
R867 T4142 T4140 punct ",",24
R868 T4143 T4140 nummod 23,24
R869 T4144 T4140 punct ",",24
R871 T4145 T4140 punct ],24
R872 T4146 T4115 punct .,shown
R873 T4148 T4149 prep In,shown
R875 T4150 T4148 pobj addition,In
R876 T4151 T4149 punct ", ",shown
R877 T4152 T4153 amod single,nucleotide
R878 T4153 T4154 compound nucleotide,polymorphisms
R880 T4154 T4149 nsubjpass polymorphisms,shown
R881 T4155 T4154 prep within,polymorphisms
R882 T4156 T4157 det the,gene
R884 T4157 T4155 pobj gene,within
R885 T4158 T4157 amod human,gene
R886 T4159 T4160 compound PGC,1α
R887 T4160 T4157 compound 1α,gene
R889 T4161 T4160 punct -,1α
R892 T4162 T4149 aux have,shown
R894 T4163 T4149 auxpass been,shown
R895 T4164 T4165 aux to,associated
R896 T4165 T4149 xcomp associated,shown
R898 T4166 T4165 auxpass be,associated
R899 T4167 T4165 prep with,associated
R900 T4168 T4167 pobj obesity,with
R902 T4169 T4168 punct ", ",obesity
R903 T4170 T4168 conj hypertension,obesity
R904 T4171 T4170 punct ", ",hypertension
R906 T4172 T4170 cc and,hypertension
R907 T4173 T4170 conj diabetes,hypertension
R909 T4174 T4175 punct [,30
R910 T4175 T4149 parataxis 30,shown
R912 T4176 T4175 nummod 25,30
R913 T4177 T4175 punct ",",30
R914 T4178 T4175 nummod 26,30
R916 T4179 T4175 punct ",",30
R917 T4180 T4175 nummod 27,30
R918 T4181 T4175 punct ",",30
R919 T4182 T4175 nummod 28,30
R921 T4183 T4175 punct ",",30
R922 T4184 T4175 nummod 29,30
R923 T4185 T4175 punct ",",30
R925 T4186 T4175 punct ],30
R926 T4187 T4149 punct .,shown