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PMC:1064854 / 45187-46982 JSONTXT 6 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T30786 0-9 JJ denotes Extensive
T30788 10-20 JJ denotes phenotypic
T30787 21-29 NNS denotes analyses
T30789 30-42 VBD denotes demonstrated
T30790 43-47 IN denotes that
T30792 48-52 NNS denotes mice
T30793 53-60 VBG denotes lacking
T30794 61-64 NN denotes PGC
T30796 64-65 HYPH denotes -
T30795 65-67 NN denotes 1α
T30791 68-71 VBP denotes are
T30797 72-78 JJ denotes unable
T30798 79-81 TO denotes to
T30799 82-86 VB denotes cope
T30800 87-91 IN denotes with
T30801 92-103 JJ denotes physiologic
T30802 104-113 NNS denotes stressors
T30803 114-122 JJ denotes relevant
T30804 123-125 IN denotes to
T30805 126-135 JJ denotes postnatal
T30806 136-144 NN denotes survival
T30807 144-145 . denotes .
T30808 145-275 sentence denotes For example, a skeletal muscle phenotype was unveiled in PGC-1α−/− mice under conditions in which energy supply becomes limiting.
T30809 146-149 IN denotes For
T30811 150-157 NN denotes example
T30812 157-159 , denotes ,
T30813 159-160 DT denotes a
T30815 161-169 JJ denotes skeletal
T30816 170-176 NN denotes muscle
T30814 177-186 NN denotes phenotype
T30817 187-190 VBD denotes was
T30810 191-199 VBN denotes unveiled
T30818 200-202 IN denotes in
T30819 203-206 NN denotes PGC
T30821 206-207 HYPH denotes -
T30820 207-209 NN denotes 1α
T30823 209-210 SYM denotes −
T30824 210-211 HYPH denotes /
T30825 211-212 SYM denotes −
T30822 213-217 NNS denotes mice
T30826 218-223 IN denotes under
T30827 224-234 NNS denotes conditions
T30828 235-237 IN denotes in
T30830 238-243 WDT denotes which
T30831 244-250 NN denotes energy
T30832 251-257 NN denotes supply
T30829 258-265 VBZ denotes becomes
T30833 266-274 JJ denotes limiting
T30834 274-275 . denotes .
T30835 275-439 sentence denotes This was most clearly demonstrated by the profound abnormalities exhibited by PGC-1α−/− mice with exercise-to-exhaustion and repetitive muscle stimulation studies.
T30836 276-280 DT denotes This
T30838 281-284 VBD denotes was
T30839 285-289 RBS denotes most
T30840 290-297 RB denotes clearly
T30837 298-310 VBN denotes demonstrated
T30841 311-313 IN denotes by
T30842 314-317 DT denotes the
T30844 318-326 JJ denotes profound
T30843 327-340 NNS denotes abnormalities
T30845 341-350 VBN denotes exhibited
T30846 351-353 IN denotes by
T30847 354-357 NN denotes PGC
T30849 357-358 HYPH denotes -
T30848 358-360 NN denotes 1α
T30851 360-361 SYM denotes −
T30852 361-362 HYPH denotes /
T30853 362-363 SYM denotes −
T30850 364-368 NNS denotes mice
T30854 369-373 IN denotes with
T30855 374-382 NN denotes exercise
T30857 382-383 HYPH denotes -
T30858 383-385 IN denotes to
T30859 385-386 HYPH denotes -
T30860 386-396 NN denotes exhaustion
T30861 397-400 CC denotes and
T30862 401-411 JJ denotes repetitive
T30864 412-418 NN denotes muscle
T30863 419-430 NN denotes stimulation
T30856 431-438 NNS denotes studies
T30865 438-439 . denotes .
T30866 439-531 sentence denotes Similarly, cardiac performance of PGC-1α−/− mice was compromised following severe exertion.
T30867 440-449 RB denotes Similarly
T30869 449-451 , denotes ,
T30870 451-458 JJ denotes cardiac
T30871 459-470 NN denotes performance
T30872 471-473 IN denotes of
T30873 474-477 NN denotes PGC
T30875 477-478 HYPH denotes -
T30874 478-480 NN denotes 1α
T30877 480-481 SYM denotes −
T30878 481-482 HYPH denotes /
T30879 482-483 SYM denotes −
T30876 484-488 NNS denotes mice
T30880 489-492 VBD denotes was
T30868 493-504 VBN denotes compromised
T30881 505-514 VBG denotes following
T30882 515-521 JJ denotes severe
T30883 522-530 NN denotes exertion
T30884 530-531 . denotes .
T30885 531-595 sentence denotes This effect was largely due to an abnormal heart rate response.
T30886 532-536 DT denotes This
T30887 537-543 NN denotes effect
T30888 544-547 VBD denotes was
T30889 548-555 RB denotes largely
T30890 556-559 IN denotes due
T30891 560-562 IN denotes to
T30892 563-565 DT denotes an
T30894 566-574 JJ denotes abnormal
T30895 575-580 NN denotes heart
T30896 581-585 NN denotes rate
T30893 586-594 NN denotes response
T30897 594-595 . denotes .
T30898 595-869 sentence denotes The basis for the observed abnormalities of cardiac heart rate, including a blunted response to β-adrenergic stimulation, is unknown, but could be related to the effects of late-stage growth arrest and corresponding derangements in energy metabolism on sinus node function.
T30899 596-599 DT denotes The
T30900 600-605 NN denotes basis
T30902 606-609 IN denotes for
T30903 610-613 DT denotes the
T30905 614-622 VBN denotes observed
T30904 623-636 NNS denotes abnormalities
T30906 637-639 IN denotes of
T30907 640-647 JJ denotes cardiac
T30909 648-653 NN denotes heart
T30908 654-658 NN denotes rate
T30910 658-660 , denotes ,
T30911 660-669 VBG denotes including
T30912 670-671 DT denotes a
T30914 672-679 JJ denotes blunted
T30913 680-688 NN denotes response
T30915 689-691 IN denotes to
T30916 692-693 NN denotes β
T30918 693-694 HYPH denotes -
T30917 694-704 JJ denotes adrenergic
T30919 705-716 NN denotes stimulation
T30920 716-718 , denotes ,
T30901 718-720 VBZ denotes is
T30921 721-728 JJ denotes unknown
T30922 728-730 , denotes ,
T30923 730-733 CC denotes but
T30924 734-739 MD denotes could
T30925 740-742 VB denotes be
T30926 743-750 JJ denotes related
T30927 751-753 IN denotes to
T30928 754-757 DT denotes the
T30929 758-765 NNS denotes effects
T30930 766-768 IN denotes of
T30931 769-773 JJ denotes late
T30933 773-774 HYPH denotes -
T30932 774-779 NN denotes stage
T30935 780-786 NN denotes growth
T30934 787-793 NN denotes arrest
T30936 794-797 CC denotes and
T30937 798-811 JJ denotes corresponding
T30938 812-824 NNS denotes derangements
T30939 825-827 IN denotes in
T30940 828-834 NN denotes energy
T30941 835-845 NN denotes metabolism
T30942 846-848 IN denotes on
T30943 849-854 NN denotes sinus
T30944 855-859 NN denotes node
T30945 860-868 NN denotes function
T30946 868-869 . denotes .
T30947 869-926 sentence denotes PGC-1α was first identified as a coactivator in BAT [2].
T30948 870-873 NN denotes PGC
T30950 873-874 HYPH denotes -
T30949 874-876 NN denotes 1α
T30952 877-880 VBD denotes was
T30953 881-886 RB denotes first
T30951 887-897 VBN denotes identified
T30954 898-900 IN denotes as
T30955 901-902 DT denotes a
T30956 903-914 NN denotes coactivator
T30957 915-917 IN denotes in
T30958 918-921 NN denotes BAT
T30959 922-923 -LRB- denotes [
T30960 923-924 CD denotes 2
T30961 924-925 -RRB- denotes ]
T30962 925-926 . denotes .
T30963 926-1179 sentence denotes Indeed, we found that exposure of the PGC-1α−/− mice to cold, another relevant physiologic stress, resulted in an untoward drop in core body temperature consistent with an abnormality in thermogenesis despite normal cold induction of UCP-1 mRNA in BAT.
T30964 927-933 RB denotes Indeed
T30966 933-935 , denotes ,
T30967 935-937 PRP denotes we
T30965 938-943 VBD denotes found
T30968 944-948 IN denotes that
T30970 949-957 NN denotes exposure
T30971 958-960 IN denotes of
T30972 961-964 DT denotes the
T30974 965-968 NN denotes PGC
T30976 968-969 HYPH denotes -
T30975 969-971 NN denotes 1α
T30977 971-972 SYM denotes −
T30978 972-973 HYPH denotes /
T30979 973-974 SYM denotes −
T30973 975-979 NNS denotes mice
T30980 980-982 IN denotes to
T30981 983-987 NN denotes cold
T30982 987-989 , denotes ,
T30983 989-996 DT denotes another
T30985 997-1005 JJ denotes relevant
T30986 1006-1017 JJ denotes physiologic
T30984 1018-1024 NN denotes stress
T30987 1024-1026 , denotes ,
T30969 1026-1034 VBD denotes resulted
T30988 1035-1037 IN denotes in
T30989 1038-1040 DT denotes an
T30991 1041-1049 JJ denotes untoward
T30990 1050-1054 NN denotes drop
T30992 1055-1057 IN denotes in
T30993 1058-1062 NN denotes core
T30995 1063-1067 NN denotes body
T30994 1068-1079 NN denotes temperature
T30996 1080-1090 JJ denotes consistent
T30997 1091-1095 IN denotes with
T30998 1096-1098 DT denotes an
T30999 1099-1110 NN denotes abnormality
T31000 1111-1113 IN denotes in
T31001 1114-1127 NN denotes thermogenesis
T31002 1128-1135 IN denotes despite
T31003 1136-1142 JJ denotes normal
T31005 1143-1147 NN denotes cold
T31004 1148-1157 NN denotes induction
T31006 1158-1160 IN denotes of
T31007 1161-1164 NN denotes UCP
T31009 1164-1165 HYPH denotes -
T31010 1165-1166 CD denotes 1
T31008 1167-1171 NN denotes mRNA
T31011 1172-1174 IN denotes in
T31012 1175-1178 NN denotes BAT
T31013 1178-1179 . denotes .
T31014 1179-1319 sentence denotes Studies with a β3-adrenergic agonist confirmed that the peak oxygen consumption rate in thermogenic tissue is diminished in PGC-1α−/− mice.
T31015 1180-1187 NNS denotes Studies
T31017 1188-1192 IN denotes with
T31018 1193-1194 DT denotes a
T31020 1195-1197 NN denotes β3
T31022 1197-1198 HYPH denotes -
T31021 1198-1208 JJ denotes adrenergic
T31019 1209-1216 NN denotes agonist
T31016 1217-1226 VBD denotes confirmed
T31023 1227-1231 IN denotes that
T31025 1232-1235 DT denotes the
T31027 1236-1240 JJ denotes peak
T31028 1241-1247 NN denotes oxygen
T31029 1248-1259 NN denotes consumption
T31026 1260-1264 NN denotes rate
T31030 1265-1267 IN denotes in
T31031 1268-1279 JJ denotes thermogenic
T31032 1280-1286 NN denotes tissue
T31033 1287-1289 VBZ denotes is
T31024 1290-1300 VBN denotes diminished
T31034 1301-1303 IN denotes in
T31035 1304-1307 NN denotes PGC
T31037 1307-1308 HYPH denotes -
T31036 1308-1310 NN denotes 1α
T31039 1310-1311 SYM denotes −
T31040 1311-1312 HYPH denotes /
T31041 1312-1313 SYM denotes −
T31038 1314-1318 NNS denotes mice
T31042 1318-1319 . denotes .
T31043 1319-1430 sentence denotes We propose that the thermogenic phenotype is related to reduced capacity for mitochondrial respiration in BAT.
T31044 1320-1322 PRP denotes We
T31045 1323-1330 VBP denotes propose
T31046 1331-1335 IN denotes that
T31048 1336-1339 DT denotes the
T31050 1340-1351 JJ denotes thermogenic
T31049 1352-1361 NN denotes phenotype
T31051 1362-1364 VBZ denotes is
T31047 1365-1372 VBN denotes related
T31052 1373-1375 IN denotes to
T31053 1376-1383 VBN denotes reduced
T31054 1384-1392 NN denotes capacity
T31055 1393-1396 IN denotes for
T31056 1397-1410 JJ denotes mitochondrial
T31057 1411-1422 NN denotes respiration
T31058 1423-1425 IN denotes in
T31059 1426-1429 NN denotes BAT
T31060 1429-1430 . denotes .
T31061 1430-1526 sentence denotes Interestingly, this phenotype was only evident during a rather narrow window of postnatal life.
T31062 1431-1444 RB denotes Interestingly
T31064 1444-1446 , denotes ,
T31065 1446-1450 DT denotes this
T31066 1451-1460 NN denotes phenotype
T31063 1461-1464 VBD denotes was
T31067 1465-1469 RB denotes only
T31068 1470-1477 JJ denotes evident
T31069 1478-1484 IN denotes during
T31070 1485-1486 DT denotes a
T31072 1487-1493 RB denotes rather
T31073 1494-1500 JJ denotes narrow
T31071 1501-1507 NN denotes window
T31074 1508-1510 IN denotes of
T31075 1511-1520 JJ denotes postnatal
T31076 1521-1525 NN denotes life
T31077 1525-1526 . denotes .
T31078 1526-1650 sentence denotes Animals at an older age did not exhibit cold intolerance, possibly due to the insulating properties of increased body mass.
T31079 1527-1534 NNS denotes Animals
T31081 1535-1537 IN denotes at
T31082 1538-1540 DT denotes an
T31084 1541-1546 JJR denotes older
T31083 1547-1550 NN denotes age
T31085 1551-1554 VBD denotes did
T31086 1555-1558 RB denotes not
T31080 1559-1566 VB denotes exhibit
T31087 1567-1571 NN denotes cold
T31088 1572-1583 NN denotes intolerance
T31089 1583-1585 , denotes ,
T31090 1585-1593 RB denotes possibly
T31091 1594-1597 IN denotes due
T31092 1598-1600 IN denotes to
T31093 1601-1604 DT denotes the
T31095 1605-1615 VBG denotes insulating
T31094 1616-1626 NNS denotes properties
T31096 1627-1629 IN denotes of
T31097 1630-1639 VBN denotes increased
T31099 1640-1644 NN denotes body
T31098 1645-1649 NN denotes mass
T31100 1649-1650 . denotes .
T31101 1650-1795 sentence denotes Collectively, these results demonstrate the importance of PGC-1α as a key transducer of physiologic stimuli to the control of energy metabolism.
T31102 1651-1663 RB denotes Collectively
T31104 1663-1665 , denotes ,
T31105 1665-1670 DT denotes these
T31106 1671-1678 NNS denotes results
T31103 1679-1690 VBP denotes demonstrate
T31107 1691-1694 DT denotes the
T31108 1695-1705 NN denotes importance
T31109 1706-1708 IN denotes of
T31110 1709-1712 NN denotes PGC
T31112 1712-1713 HYPH denotes -
T31111 1713-1715 NN denotes 1α
T31113 1716-1718 IN denotes as
T31114 1719-1720 DT denotes a
T31116 1721-1724 JJ denotes key
T31115 1725-1735 NN denotes transducer
T31117 1736-1738 IN denotes of
T31118 1739-1750 JJ denotes physiologic
T31119 1751-1758 NNS denotes stimuli
T31120 1759-1761 IN denotes to
T31121 1762-1765 DT denotes the
T31122 1766-1773 NN denotes control
T31123 1774-1776 IN denotes of
T31124 1777-1783 NN denotes energy
T31125 1784-1794 NN denotes metabolism
T31126 1794-1795 . denotes .
R6403 T30786 T30787 amod Extensive,analyses
R6404 T30787 T30789 nsubj analyses,demonstrated
R6406 T30788 T30787 amod phenotypic,analyses
R6407 T30790 T30791 mark that,are
R6409 T30791 T30789 ccomp are,demonstrated
R6410 T30792 T30791 nsubj mice,are
R6411 T30793 T30792 acl lacking,mice
R6413 T30794 T30795 compound PGC,1α
R6414 T30795 T30793 dobj 1α,lacking
R6415 T30796 T30795 punct -,1α
R6417 T30797 T30791 acomp unable,are
R6418 T30798 T30799 aux to,cope
R6420 T30799 T30797 xcomp cope,unable
R6421 T30800 T30799 prep with,cope
R6422 T30801 T30802 amod physiologic,stressors
R6424 T30802 T30800 pobj stressors,with
R6428 T30803 T30802 amod relevant,stressors
R6429 T30804 T30803 prep to,relevant
R6431 T30805 T30806 amod postnatal,survival
R6432 T30806 T30804 pobj survival,to
R6433 T30807 T30789 punct .,demonstrated
R6435 T30809 T30810 prep For,unveiled
R6437 T30811 T30809 pobj example,For
R6438 T30812 T30810 punct ", ",unveiled
R6439 T30813 T30814 det a,phenotype
R6440 T30814 T30810 nsubjpass phenotype,unveiled
R6442 T30815 T30816 amod skeletal,muscle
R6443 T30816 T30814 compound muscle,phenotype
R6444 T30817 T30810 auxpass was,unveiled
R6445 T30818 T30810 prep in,unveiled
R6446 T30819 T30820 nmod PGC,1α
R6447 T30909 T30908 compound heart,rate
R6448 T30820 T30822 nmod 1α,mice
R6449 T30821 T30820 punct -,1α
R6450 T30822 T30818 pobj mice,in
R6451 T30823 T30820 punct −,1α
R6452 T30910 T30904 punct ", ",abnormalities
R6453 T30824 T30820 punct /,1α
R6454 T30825 T30820 punct −,1α
R6455 T30911 T30904 prep including,abnormalities
R6456 T30826 T30810 prep under,unveiled
R6457 T30827 T30826 pobj conditions,under
R6458 T30828 T30829 prep in,becomes
R6459 T30912 T30913 det a,response
R6460 T30829 T30827 relcl becomes,conditions
R6461 T30830 T30828 pobj which,in
R6462 T30831 T30832 compound energy,supply
R6463 T30913 T30911 pobj response,including
R6464 T30832 T30829 nsubj supply,becomes
R6465 T30833 T30829 acomp limiting,becomes
R6466 T30914 T30913 amod blunted,response
R6467 T30834 T30810 punct .,unveiled
R6468 T30836 T30837 nsubjpass This,demonstrated
R6469 T30915 T30913 prep to,response
R6470 T30838 T30837 auxpass was,demonstrated
R6471 T30916 T30917 npadvmod β,adrenergic
R6472 T30839 T30840 advmod most,clearly
R6473 T30840 T30837 advmod clearly,demonstrated
R6474 T30841 T30837 agent by,demonstrated
R6475 T30917 T30919 amod adrenergic,stimulation
R6476 T30842 T30843 det the,abnormalities
R6477 T30843 T30841 pobj abnormalities,by
R6478 T30844 T30843 amod profound,abnormalities
R6479 T30918 T30917 punct -,adrenergic
R6480 T30845 T30843 acl exhibited,abnormalities
R6481 T30846 T30845 agent by,exhibited
R6482 T30847 T30848 nmod PGC,1α
R6483 T30919 T30915 pobj stimulation,to
R6484 T30920 T30901 punct ", ",is
R6485 T30921 T30901 acomp unknown,is
R6486 T30848 T30850 nmod 1α,mice
R6487 T30849 T30848 punct -,1α
R6488 T30922 T30901 punct ", ",is
R6489 T30850 T30846 pobj mice,by
R6490 T30851 T30848 punct −,1α
R6491 T30852 T30848 punct /,1α
R6492 T30853 T30848 punct −,1α
R6493 T30854 T30845 prep with,exhibited
R6494 T30923 T30901 cc but,is
R6495 T30855 T30856 nmod exercise,studies
R6496 T30856 T30854 pobj studies,with
R6497 T30924 T30925 aux could,be
R6498 T30857 T30855 punct -,exercise
R6499 T30858 T30855 prep to,exercise
R6500 T30859 T30858 punct -,to
R6501 T30860 T30858 pobj exhaustion,to
R6502 T30925 T30901 conj be,is
R6503 T30861 T30855 cc and,exercise
R6504 T30862 T30863 amod repetitive,stimulation
R6505 T30926 T30925 acomp related,be
R6506 T30863 T30855 conj stimulation,exercise
R6507 T30864 T30863 compound muscle,stimulation
R6508 T30865 T30837 punct .,demonstrated
R6509 T30927 T30926 prep to,related
R6510 T30867 T30868 advmod Similarly,compromised
R6511 T30928 T30929 det the,effects
R6512 T30869 T30868 punct ", ",compromised
R6513 T30870 T30871 amod cardiac,performance
R6514 T30929 T30927 pobj effects,to
R6515 T30871 T30868 nsubjpass performance,compromised
R6516 T30872 T30871 prep of,performance
R6517 T30930 T30929 prep of,effects
R6518 T30873 T30874 nmod PGC,1α
R6519 T30874 T30876 nmod 1α,mice
R6520 T30875 T30874 punct -,1α
R6521 T30931 T30932 amod late,stage
R6522 T30876 T30872 pobj mice,of
R6523 T30877 T30874 punct −,1α
R6524 T30878 T30874 punct /,1α
R6525 T30932 T30934 compound stage,arrest
R6526 T30879 T30874 punct −,1α
R6527 T30880 T30868 auxpass was,compromised
R6528 T30881 T30868 prep following,compromised
R6529 T30933 T30932 punct -,stage
R6530 T30882 T30883 amod severe,exertion
R6531 T30883 T30881 pobj exertion,following
R6532 T30884 T30868 punct .,compromised
R6533 T30934 T30930 pobj arrest,of
R6534 T30886 T30887 det This,effect
R6535 T30887 T30888 nsubj effect,was
R6536 T30935 T30934 compound growth,arrest
R6537 T30889 T30888 advmod largely,was
R6538 T30890 T30888 prep due,was
R6539 T30936 T30929 cc and,effects
R6540 T30891 T30890 pcomp to,due
R6541 T30892 T30893 det an,response
R6542 T30937 T30938 amod corresponding,derangements
R6543 T30893 T30890 pobj response,due
R6544 T30894 T30893 amod abnormal,response
R6545 T30895 T30896 compound heart,rate
R6546 T30896 T30893 compound rate,response
R6547 T30897 T30888 punct .,was
R6548 T30938 T30929 conj derangements,effects
R6549 T30899 T30900 det The,basis
R6550 T30900 T30901 nsubj basis,is
R6551 T30939 T30938 prep in,derangements
R6552 T30902 T30900 prep for,basis
R6553 T30903 T30904 det the,abnormalities
R6554 T30904 T30902 pobj abnormalities,for
R6555 T30940 T30941 compound energy,metabolism
R6556 T30905 T30904 amod observed,abnormalities
R6557 T30906 T30904 prep of,abnormalities
R6558 T30941 T30939 pobj metabolism,in
R6559 T30907 T30908 amod cardiac,rate
R6560 T30908 T30906 pobj rate,of
R6561 T30942 T30938 prep on,derangements
R6562 T30943 T30944 compound sinus,node
R6563 T30944 T30945 compound node,function
R6564 T30945 T30942 pobj function,on
R6565 T31015 T31016 nsubj Studies,confirmed
R6566 T31017 T31015 prep with,Studies
R6567 T30946 T30901 punct .,is
R6568 T31018 T31019 det a,agonist
R6569 T30948 T30949 compound PGC,1α
R6570 T31019 T31017 pobj agonist,with
R6571 T30949 T30951 nsubjpass 1α,identified
R6572 T31020 T31021 npadvmod β3,adrenergic
R6573 T31021 T31019 amod adrenergic,agonist
R6574 T31022 T31021 punct -,adrenergic
R6575 T30950 T30949 punct -,1α
R6576 T31023 T31024 mark that,diminished
R6577 T31024 T31016 ccomp diminished,confirmed
R6578 T31025 T31026 det the,rate
R6579 T30952 T30951 auxpass was,identified
R6580 T31026 T31024 nsubjpass rate,diminished
R6581 T31027 T31026 amod peak,rate
R6582 T31028 T31029 compound oxygen,consumption
R6583 T31029 T31026 compound consumption,rate
R6584 T30953 T30951 advmod first,identified
R6585 T31030 T31026 prep in,rate
R6586 T31031 T31032 amod thermogenic,tissue
R6587 T30954 T30951 prep as,identified
R6588 T31032 T31030 pobj tissue,in
R6589 T31033 T31024 auxpass is,diminished
R6590 T31034 T31024 prep in,diminished
R6591 T30955 T30956 det a,coactivator
R6592 T31035 T31036 nmod PGC,1α
R6593 T31036 T31038 nmod 1α,mice
R6594 T31037 T31036 punct -,1α
R6595 T31038 T31034 pobj mice,in
R6596 T31039 T31036 punct −,1α
R6597 T31040 T31036 punct /,1α
R6598 T30956 T30954 pobj coactivator,as
R6599 T31041 T31036 punct −,1α
R6600 T31042 T31016 punct .,confirmed
R6601 T30957 T30951 prep in,identified
R6602 T31044 T31045 nsubj We,propose
R6603 T31046 T31047 mark that,related
R6604 T30958 T30957 pobj BAT,in
R6605 T31047 T31045 ccomp related,propose
R6606 T31048 T31049 det the,phenotype
R6607 T30959 T30960 punct [,2
R6608 T31049 T31047 nsubjpass phenotype,related
R6609 T31050 T31049 amod thermogenic,phenotype
R6610 T31051 T31047 auxpass is,related
R6611 T30960 T30951 parataxis 2,identified
R6612 T31052 T31047 prep to,related
R6613 T31053 T31054 amod reduced,capacity
R6614 T31054 T31052 pobj capacity,to
R6615 T30961 T30960 punct ],2
R6616 T31055 T31054 prep for,capacity
R6617 T31056 T31057 amod mitochondrial,respiration
R6618 T30962 T30951 punct .,identified
R6619 T31057 T31055 pobj respiration,for
R6620 T31058 T31054 prep in,capacity
R6621 T30964 T30965 advmod Indeed,found
R6622 T31059 T31058 pobj BAT,in
R6623 T31060 T31045 punct .,propose
R6624 T31062 T31063 advmod Interestingly,was
R6625 T30966 T30965 punct ", ",found
R6626 T31064 T31063 punct ", ",was
R6627 T31065 T31066 det this,phenotype
R6628 T31066 T31063 nsubj phenotype,was
R6629 T31067 T31063 advmod only,was
R6630 T30967 T30965 nsubj we,found
R6631 T31068 T31063 acomp evident,was
R6632 T31069 T31063 prep during,was
R6633 T31070 T31071 det a,window
R6634 T30968 T30969 mark that,resulted
R6635 T31071 T31069 pobj window,during
R6636 T31072 T31073 advmod rather,narrow
R6637 T31073 T31071 amod narrow,window
R6638 T30969 T30965 ccomp resulted,found
R6639 T31074 T31071 prep of,window
R6640 T31075 T31076 amod postnatal,life
R6641 T30970 T30969 nsubj exposure,resulted
R6642 T31076 T31074 pobj life,of
R6643 T31077 T31063 punct .,was
R6644 T30971 T30970 prep of,exposure
R6645 T31079 T31080 nsubj Animals,exhibit
R6646 T30972 T30973 det the,mice
R6647 T31081 T31079 prep at,Animals
R6648 T31082 T31083 det an,age
R6649 T31083 T31081 pobj age,at
R6650 T31084 T31083 amod older,age
R6651 T31085 T31080 aux did,exhibit
R6652 T31086 T31080 neg not,exhibit
R6653 T30973 T30971 pobj mice,of
R6654 T31087 T31088 compound cold,intolerance
R6655 T31088 T31080 dobj intolerance,exhibit
R6656 T31089 T31080 punct ", ",exhibit
R6657 T30974 T30975 nmod PGC,1α
R6658 T31090 T31091 advmod possibly,due
R6659 T31091 T31080 prep due,exhibit
R6660 T31092 T31091 pcomp to,due
R6661 T30975 T30973 nmod 1α,mice
R6662 T31093 T31094 det the,properties
R6663 T31094 T31091 pobj properties,due
R6664 T31095 T31094 amod insulating,properties
R6665 T30976 T30975 punct -,1α
R6666 T31096 T31094 prep of,properties
R6667 T31097 T31098 amod increased,mass
R6668 T31098 T31096 pobj mass,of
R6669 T30977 T30975 punct −,1α
R6670 T31099 T31098 compound body,mass
R6671 T31100 T31080 punct .,exhibit
R6672 T30978 T30975 punct /,1α
R6673 T31102 T31103 advmod Collectively,demonstrate
R6674 T30979 T30975 punct −,1α
R6675 T31104 T31103 punct ", ",demonstrate
R6676 T31105 T31106 det these,results
R6677 T31106 T31103 nsubj results,demonstrate
R6678 T30980 T30970 prep to,exposure
R6679 T31107 T31108 det the,importance
R6680 T31108 T31103 dobj importance,demonstrate
R6681 T31109 T31108 prep of,importance
R6682 T30981 T30980 pobj cold,to
R6683 T31110 T31111 compound PGC,1α
R6684 T30982 T30981 punct ", ",cold
R6685 T31111 T31109 pobj 1α,of
R6686 T30983 T30984 det another,stress
R6687 T31112 T31111 punct -,1α
R6688 T31113 T31108 prep as,importance
R6689 T30984 T30981 appos stress,cold
R6690 T31114 T31115 det a,transducer
R6691 T31115 T31113 pobj transducer,as
R6692 T31116 T31115 amod key,transducer
R6693 T30985 T30984 amod relevant,stress
R6694 T31117 T31115 prep of,transducer
R6695 T31118 T31119 amod physiologic,stimuli
R6696 T31119 T31117 pobj stimuli,of
R6697 T30986 T30984 amod physiologic,stress
R6698 T31120 T31115 prep to,transducer
R6699 T30987 T30969 punct ", ",resulted
R6700 T30988 T30969 prep in,resulted
R6701 T30989 T30990 det an,drop
R6702 T31121 T31122 det the,control
R6703 T31122 T31120 pobj control,to
R6704 T30990 T30988 pobj drop,in
R6705 T31123 T31122 prep of,control
R6706 T31124 T31125 compound energy,metabolism
R6707 T30991 T30990 amod untoward,drop
R6708 T31125 T31123 pobj metabolism,of
R6709 T31126 T31103 punct .,demonstrate
R6710 T30992 T30990 prep in,drop
R6713 T30993 T30994 compound core,temperature
R6716 T30994 T30992 pobj temperature,in
R6720 T30995 T30994 compound body,temperature
R6724 T30996 T30969 advcl consistent,resulted
R6727 T30997 T30996 prep with,consistent
R6731 T30998 T30999 det an,abnormality
R6734 T30999 T30997 pobj abnormality,with
R6738 T31000 T30999 prep in,abnormality
R6742 T31001 T31000 pobj thermogenesis,in
R6746 T31002 T30996 prep despite,consistent
R6750 T31003 T31004 amod normal,induction
R6755 T31004 T31002 pobj induction,despite
R6758 T31005 T31004 compound cold,induction
R6762 T31006 T31004 prep of,induction
R6765 T31007 T31008 nmod UCP,mRNA
R6767 T31008 T31006 pobj mRNA,of
R6769 T31009 T31007 punct -,UCP
R6771 T31010 T31007 nummod 1,UCP
R6775 T31011 T31004 prep in,induction
R6778 T31012 T31011 pobj BAT,in
R6782 T31013 T30965 punct .,found