PMC:1064854 / 38266-40020 JSONTXT 7 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T22559 0-6 JJ denotes Recent
T22560 7-14 NNS denotes studies
T22562 15-19 VBP denotes have
T22561 20-29 VBN denotes suggested
T22563 30-34 IN denotes that
T22565 35-43 JJ denotes specific
T22567 44-47 NN denotes PGC
T22568 47-48 HYPH denotes -
T22566 48-50 NN denotes
T22569 51-57 JJ denotes single
T22570 58-68 NN denotes nucleotide
T22571 69-82 NNS denotes polymorphisms
T22572 83-86 CC denotes and
T22573 87-97 NNS denotes haplotypes
T22574 98-101 MD denotes may
T22564 102-111 VB denotes influence
T22575 112-115 DT denotes the
T22576 116-127 NN denotes development
T22577 128-130 IN denotes of
T22578 131-138 NN denotes insulin
T22579 139-149 NN denotes resistance
T22580 150-153 CC denotes and
T22581 154-162 NN denotes diabetes
T22582 163-164 -LRB- denotes [
T22584 164-166 CD denotes 27
T22585 166-167 , denotes ,
T22583 167-169 CD denotes 30
T22586 169-170 -RRB- denotes ]
T22587 171-174 CC denotes and
T22588 175-179 IN denotes that
T22590 180-183 NN denotes PGC
T22592 183-184 HYPH denotes -
T22593 184-185 CD denotes 1
T22591 186-194 NN denotes activity
T22594 195-197 VBZ denotes is
T22589 198-208 VBN denotes diminished
T22595 209-211 IN denotes in
T22596 212-219 NN denotes insulin
T22598 219-220 HYPH denotes -
T22597 220-229 JJ denotes resistant
T22600 230-233 CC denotes and
T22601 234-242 JJ denotes diabetic
T22599 243-249 NN denotes muscle
T22602 250-251 -LRB- denotes [
T22604 251-253 CD denotes 22
T22605 253-254 , denotes ,
T22603 254-256 CD denotes 23
T22606 256-257 -RRB- denotes ]
T22607 257-258 . denotes .
T22608 258-359 sentence denotes Accordingly, peripheral glucose disposal and insulin responsiveness were examined in PGC-1α−/− mice.
T22609 259-270 RB denotes Accordingly
T22611 270-272 , denotes ,
T22612 272-282 JJ denotes peripheral
T22614 283-290 NN denotes glucose
T22613 291-299 NN denotes disposal
T22615 300-303 CC denotes and
T22616 304-311 NN denotes insulin
T22617 312-326 NN denotes responsiveness
T22618 327-331 VBD denotes were
T22610 332-340 VBN denotes examined
T22619 341-343 IN denotes in
T22620 344-347 NN denotes PGC
T22622 347-348 HYPH denotes -
T22621 348-350 NN denotes
T22624 350-351 SYM denotes
T22625 351-352 HYPH denotes /
T22626 352-353 SYM denotes
T22623 354-358 NNS denotes mice
T22627 358-359 . denotes .
T22628 359-539 sentence denotes Glucose tolerance testing of 2-mo-old male and female mice revealed no significant difference in blood glucose excursion between PGC-1α+/+ and PGC-1α−/− groups (unpublished data).
T22629 360-367 NN denotes Glucose
T22630 368-377 NN denotes tolerance
T22631 378-385 NN denotes testing
T22633 386-388 IN denotes of
T22634 389-390 CD denotes 2
T22636 390-391 HYPH denotes -
T22635 391-393 NN denotes mo
T22638 393-394 HYPH denotes -
T22637 394-397 JJ denotes old
T22640 398-402 JJ denotes male
T22641 403-406 CC denotes and
T22642 407-413 JJ denotes female
T22639 414-418 NNS denotes mice
T22632 419-427 VBD denotes revealed
T22643 428-430 DT denotes no
T22645 431-442 JJ denotes significant
T22644 443-453 NN denotes difference
T22646 454-456 IN denotes in
T22647 457-462 NN denotes blood
T22648 463-470 NN denotes glucose
T22649 471-480 NN denotes excursion
T22650 481-488 IN denotes between
T22651 489-492 NN denotes PGC
T22653 492-493 HYPH denotes -
T22652 493-495 NN denotes
T22655 495-496 SYM denotes +
T22656 496-497 HYPH denotes /
T22657 497-498 SYM denotes +
T22658 499-502 CC denotes and
T22659 503-506 NN denotes PGC
T22661 506-507 HYPH denotes -
T22660 507-509 NN denotes
T22662 509-510 SYM denotes
T22663 510-511 HYPH denotes /
T22664 511-512 SYM denotes
T22654 513-519 NNS denotes groups
T22665 520-521 -LRB- denotes (
T22667 521-532 JJ denotes unpublished
T22666 533-537 NNS denotes data
T22668 537-538 -RRB- denotes )
T22669 538-539 . denotes .
T22670 539-701 sentence denotes Given that older female PGC-1α−/− mice develop an increase in body fat stores, glucose tolerance and insulin responsiveness were further evaluated in this group.
T22671 540-545 VBN denotes Given
T22673 546-550 IN denotes that
T22675 551-556 JJR denotes older
T22677 557-563 JJ denotes female
T22678 564-567 NN denotes PGC
T22680 567-568 HYPH denotes -
T22679 568-570 NN denotes
T22681 570-571 SYM denotes
T22682 571-572 HYPH denotes /
T22683 572-573 SYM denotes
T22676 574-578 NNS denotes mice
T22674 579-586 VBP denotes develop
T22684 587-589 DT denotes an
T22685 590-598 NN denotes increase
T22686 599-601 IN denotes in
T22687 602-606 NN denotes body
T22688 607-610 NN denotes fat
T22689 611-617 NNS denotes stores
T22690 617-619 , denotes ,
T22691 619-626 NN denotes glucose
T22692 627-636 NN denotes tolerance
T22693 637-640 CC denotes and
T22694 641-648 NN denotes insulin
T22695 649-663 NN denotes responsiveness
T22696 664-668 VBD denotes were
T22697 669-676 RB denotes further
T22672 677-686 VBN denotes evaluated
T22698 687-689 IN denotes in
T22699 690-694 DT denotes this
T22700 695-700 NN denotes group
T22701 700-701 . denotes .
T22702 701-1041 sentence denotes Glucose tolerance testing in 4.5-mo-old female PGC-1α−/− mice revealed that, despite increased body weight [mean ± standard error of the mean (SEM) weight of PGC-1α+/+ mice = 22.4 ± 0.79 g; PGC-1α−/− mice = 25.2 ± 1.04 g), PGC-1α−/− mice exhibited similar levels of glucose tolerance compared to WT mice on standard rodent chow (Figure 9).
T22703 702-709 NN denotes Glucose
T22704 710-719 NN denotes tolerance
T22705 720-727 NN denotes testing
T22707 728-730 IN denotes in
T22708 731-734 CD denotes 4.5
T22710 734-735 HYPH denotes -
T22709 735-737 NN denotes mo
T22712 737-738 HYPH denotes -
T22711 738-741 JJ denotes old
T22714 742-748 JJ denotes female
T22715 749-752 NN denotes PGC
T22717 752-753 HYPH denotes -
T22716 753-755 NN denotes
T22718 755-756 SYM denotes
T22719 756-757 HYPH denotes /
T22720 757-758 SYM denotes
T22713 759-763 NNS denotes mice
T22706 764-772 VBD denotes revealed
T22721 773-777 IN denotes that
T22723 777-779 , denotes ,
T22724 779-786 IN denotes despite
T22725 787-796 VBN denotes increased
T22727 797-801 NN denotes body
T22726 802-808 NN denotes weight
T22728 809-810 -LRB- denotes [
T22730 810-814 NN denotes mean
T22732 815-816 SYM denotes ±
T22733 817-825 JJ denotes standard
T22734 826-831 NN denotes error
T22735 832-834 IN denotes of
T22736 835-838 DT denotes the
T22737 839-843 NN denotes mean
T22738 844-845 -LRB- denotes (
T22739 845-848 NN denotes SEM
T22740 848-849 -RRB- denotes )
T22731 850-856 NN denotes weight
T22742 857-859 IN denotes of
T22743 860-863 NN denotes PGC
T22745 863-864 HYPH denotes -
T22744 864-866 NN denotes
T22747 866-867 SYM denotes +
T22748 867-868 HYPH denotes /
T22749 868-869 SYM denotes +
T22746 870-874 NNS denotes mice
T22750 875-876 SYM denotes =
T22751 877-881 CD denotes 22.4
T22753 882-883 SYM denotes ±
T22752 884-888 CD denotes 0.79
T22741 889-890 NN denotes g
T22754 890-891 : denotes ;
T22755 892-895 NN denotes PGC
T22757 895-896 HYPH denotes -
T22756 896-898 NN denotes
T22759 898-899 SYM denotes
T22760 899-900 HYPH denotes /
T22761 900-901 SYM denotes
T22758 902-906 NNS denotes mice
T22762 907-908 SYM denotes =
T22763 909-913 CD denotes 25.2
T22765 914-915 SYM denotes ±
T22764 916-920 CD denotes 1.04
T22729 921-922 NN denotes g
T22766 922-923 -RRB- denotes )
T22767 923-925 , denotes ,
T22768 925-928 NN denotes PGC
T22770 928-929 HYPH denotes -
T22769 929-931 NN denotes
T22772 931-932 SYM denotes
T22773 932-933 HYPH denotes /
T22774 933-934 SYM denotes
T22771 935-939 NNS denotes mice
T22722 940-949 VBD denotes exhibited
T22775 950-957 JJ denotes similar
T22776 958-964 NNS denotes levels
T22777 965-967 IN denotes of
T22778 968-975 NN denotes glucose
T22779 976-985 NN denotes tolerance
T22780 986-994 VBN denotes compared
T22781 995-997 IN denotes to
T22782 998-1000 NN denotes WT
T22783 1001-1005 NNS denotes mice
T22784 1006-1008 IN denotes on
T22785 1009-1017 JJ denotes standard
T22787 1018-1024 NN denotes rodent
T22786 1025-1029 NN denotes chow
T22788 1030-1031 -LRB- denotes (
T22789 1031-1037 NN denotes Figure
T22790 1038-1039 CD denotes 9
T22791 1039-1040 -RRB- denotes )
T22792 1040-1041 . denotes .
T22793 1041-1225 sentence denotes To examine glucose homeostasis in response to high-fat diet, female PGC-1α+/+ and PGC-1α−/− mice were placed on high-fat chow (43% calories from fat) for 6 wk starting at 8 wk of age.
T22794 1042-1044 TO denotes To
T22795 1045-1052 VB denotes examine
T22797 1053-1060 NN denotes glucose
T22798 1061-1072 NN denotes homeostasis
T22799 1073-1075 IN denotes in
T22800 1076-1084 NN denotes response
T22801 1085-1087 IN denotes to
T22802 1088-1092 JJ denotes high
T22804 1092-1093 HYPH denotes -
T22803 1093-1096 NN denotes fat
T22805 1097-1101 NN denotes diet
T22806 1101-1103 , denotes ,
T22807 1103-1109 JJ denotes female
T22809 1110-1113 NN denotes PGC
T22811 1113-1114 HYPH denotes -
T22810 1114-1116 NN denotes
T22812 1116-1117 SYM denotes +
T22813 1117-1118 HYPH denotes /
T22814 1118-1119 SYM denotes +
T22815 1120-1123 CC denotes and
T22816 1124-1127 NN denotes PGC
T22818 1127-1128 HYPH denotes -
T22817 1128-1130 NN denotes
T22819 1130-1131 SYM denotes
T22820 1131-1132 HYPH denotes /
T22821 1132-1133 SYM denotes
T22808 1134-1138 NNS denotes mice
T22822 1139-1143 VBD denotes were
T22796 1144-1150 VBN denotes placed
T22823 1151-1153 IN denotes on
T22824 1154-1158 JJ denotes high
T22826 1158-1159 HYPH denotes -
T22825 1159-1162 NN denotes fat
T22827 1163-1167 NN denotes chow
T22828 1168-1169 -LRB- denotes (
T22830 1169-1171 CD denotes 43
T22831 1171-1172 NN denotes %
T22829 1173-1181 NNS denotes calories
T22832 1182-1186 IN denotes from
T22833 1187-1190 NN denotes fat
T22834 1190-1191 -RRB- denotes )
T22835 1192-1195 IN denotes for
T22836 1196-1197 CD denotes 6
T22837 1198-1200 NN denotes wk
T22838 1201-1209 VBG denotes starting
T22839 1210-1212 IN denotes at
T22840 1213-1214 CD denotes 8
T22841 1215-1217 NN denotes wk
T22842 1218-1220 IN denotes of
T22843 1221-1224 NN denotes age
T22844 1224-1225 . denotes .
T22845 1225-1328 sentence denotes The weight gained on the high-fat diet was similar for the PGC-1α+/+ and PGC-1α−/− groups (Figure S3).
T22846 1226-1229 DT denotes The
T22847 1230-1236 NN denotes weight
T22849 1237-1243 VBN denotes gained
T22850 1244-1246 IN denotes on
T22851 1247-1250 DT denotes the
T22853 1251-1255 JJ denotes high
T22855 1255-1256 HYPH denotes -
T22854 1256-1259 NN denotes fat
T22852 1260-1264 NN denotes diet
T22848 1265-1268 VBD denotes was
T22856 1269-1276 JJ denotes similar
T22857 1277-1280 IN denotes for
T22858 1281-1284 DT denotes the
T22860 1285-1288 NN denotes PGC
T22862 1288-1289 HYPH denotes -
T22861 1289-1291 NN denotes
T22863 1291-1292 SYM denotes +
T22864 1292-1293 HYPH denotes /
T22865 1293-1294 SYM denotes +
T22866 1295-1298 CC denotes and
T22867 1299-1302 NN denotes PGC
T22869 1302-1303 HYPH denotes -
T22868 1303-1305 NN denotes
T22870 1305-1306 SYM denotes
T22871 1306-1307 HYPH denotes /
T22872 1307-1308 SYM denotes
T22859 1309-1315 NNS denotes groups
T22873 1316-1317 -LRB- denotes (
T22875 1317-1323 NN denotes Figure
T22874 1324-1326 NN denotes S3
T22876 1326-1327 -RRB- denotes )
T22877 1327-1328 . denotes .
T22878 1328-1487 sentence denotes Surprisingly, the PGC-1α−/− mice on a high-fat diet were significantly more glucose-tolerant and insulin-sensitive compared to the PGC-1α+/+ mice (Figure 9B).
T22879 1329-1341 RB denotes Surprisingly
T22881 1341-1343 , denotes ,
T22882 1343-1346 DT denotes the
T22884 1347-1350 NN denotes PGC
T22886 1350-1351 HYPH denotes -
T22885 1351-1353 NN denotes
T22887 1353-1354 SYM denotes
T22888 1354-1355 HYPH denotes /
T22889 1355-1356 SYM denotes
T22883 1357-1361 NNS denotes mice
T22890 1362-1364 IN denotes on
T22891 1365-1366 DT denotes a
T22893 1367-1371 JJ denotes high
T22895 1371-1372 HYPH denotes -
T22894 1372-1375 NN denotes fat
T22892 1376-1380 NN denotes diet
T22880 1381-1385 VBD denotes were
T22896 1386-1399 RB denotes significantly
T22897 1400-1404 RBR denotes more
T22899 1405-1412 NN denotes glucose
T22900 1412-1413 HYPH denotes -
T22898 1413-1421 JJ denotes tolerant
T22901 1422-1425 CC denotes and
T22902 1426-1433 NN denotes insulin
T22904 1433-1434 HYPH denotes -
T22903 1434-1443 JJ denotes sensitive
T22905 1444-1452 VBN denotes compared
T22906 1453-1455 IN denotes to
T22907 1456-1459 DT denotes the
T22909 1460-1463 NN denotes PGC
T22911 1463-1464 HYPH denotes -
T22910 1464-1466 NN denotes
T22912 1466-1467 SYM denotes +
T22913 1467-1468 HYPH denotes /
T22914 1468-1469 SYM denotes +
T22908 1470-1474 NNS denotes mice
T22915 1475-1476 -LRB- denotes (
T22917 1476-1482 NN denotes Figure
T22916 1483-1485 NN denotes 9B
T22918 1485-1486 -RRB- denotes )
T22919 1486-1487 . denotes .
T22920 1487-1644 sentence denotes Taken together, these results indicate that, despite excess body fat under standard conditions, the female PGC-1α−/− mice do not exhibit insulin resistance.
T22921 1488-1493 VBN denotes Taken
T22923 1494-1502 RB denotes together
T22924 1502-1504 , denotes ,
T22925 1504-1509 DT denotes these
T22926 1510-1517 NNS denotes results
T22922 1518-1526 VBP denotes indicate
T22927 1527-1531 IN denotes that
T22929 1531-1533 , denotes ,
T22930 1533-1540 IN denotes despite
T22931 1541-1547 JJ denotes excess
T22933 1548-1552 NN denotes body
T22932 1553-1556 NN denotes fat
T22934 1557-1562 IN denotes under
T22935 1563-1571 JJ denotes standard
T22936 1572-1582 NNS denotes conditions
T22937 1582-1584 , denotes ,
T22938 1584-1587 DT denotes the
T22940 1588-1594 JJ denotes female
T22941 1595-1598 NN denotes PGC
T22943 1598-1599 HYPH denotes -
T22942 1599-1601 NN denotes
T22944 1601-1602 SYM denotes
T22945 1602-1603 HYPH denotes /
T22946 1603-1604 SYM denotes
T22939 1605-1609 NNS denotes mice
T22947 1610-1612 VBP denotes do
T22948 1613-1616 RB denotes not
T22928 1617-1624 VB denotes exhibit
T22949 1625-1632 NN denotes insulin
T22950 1633-1643 NN denotes resistance
T22951 1643-1644 . denotes .
T22952 1644-1754 sentence denotes Moreover, the PGC-1α−/− mice are more glucose-tolerant and insulin-sensitive than WT mice on a high-fat diet.
T22953 1645-1653 RB denotes Moreover
T22955 1653-1655 , denotes ,
T22956 1655-1658 DT denotes the
T22958 1659-1662 NN denotes PGC
T22960 1662-1663 HYPH denotes -
T22959 1663-1665 NN denotes
T22961 1665-1666 SYM denotes
T22962 1666-1667 HYPH denotes /
T22963 1667-1668 SYM denotes
T22957 1669-1673 NNS denotes mice
T22954 1674-1677 VBP denotes are
T22964 1678-1682 RBR denotes more
T22966 1683-1690 NN denotes glucose
T22967 1690-1691 HYPH denotes -
T22965 1691-1699 JJ denotes tolerant
T22968 1700-1703 CC denotes and
T22969 1704-1711 NN denotes insulin
T22971 1711-1712 HYPH denotes -
T22970 1712-1721 JJ denotes sensitive
T22972 1722-1726 IN denotes than
T22973 1727-1729 NN denotes WT
T22974 1730-1734 NNS denotes mice
T22975 1735-1737 IN denotes on
T22976 1738-1739 DT denotes a
T22978 1740-1744 JJ denotes high
T22980 1744-1745 HYPH denotes -
T22979 1745-1748 NN denotes fat
T22977 1749-1753 NN denotes diet
T22981 1753-1754 . denotes .
R5304 T22559 T22560 amod Recent,studies
R5305 T22560 T22561 nsubj studies,suggested
R5306 T22562 T22561 aux have,suggested
R5307 T22563 T22564 mark that,influence
R5308 T22564 T22561 advcl influence,suggested
R5309 T22565 T22566 amod specific,1α
R5310 T22566 T22564 nsubj 1α,influence
R5311 T22567 T22566 compound PGC,1α
R5312 T22568 T22566 punct -,1α
R5313 T22569 T22570 amod single,nucleotide
R5314 T22570 T22571 compound nucleotide,polymorphisms
R5315 T22571 T22566 appos polymorphisms,1α
R5316 T22572 T22571 cc and,polymorphisms
R5317 T22573 T22571 conj haplotypes,polymorphisms
R5318 T22574 T22564 aux may,influence
R5319 T22575 T22576 det the,development
R5320 T22576 T22564 dobj development,influence
R5321 T22577 T22576 prep of,development
R5322 T22578 T22579 compound insulin,resistance
R5323 T22579 T22577 pobj resistance,of
R5324 T22580 T22579 cc and,resistance
R5325 T22581 T22579 conj diabetes,resistance
R5326 T22582 T22583 punct [,30
R5327 T22583 T22564 parataxis 30,influence
R5328 T22584 T22583 nummod 27,30
R5329 T22585 T22583 punct ",",30
R5330 T22586 T22583 punct ],30
R5331 T22587 T22564 cc and,influence
R5332 T22588 T22589 mark that,diminished
R5333 T22589 T22564 conj diminished,influence
R5334 T22590 T22591 nmod PGC,activity
R5335 T22591 T22589 nsubjpass activity,diminished
R5336 T22592 T22590 punct -,PGC
R5337 T22593 T22590 nummod 1,PGC
R5338 T22594 T22589 auxpass is,diminished
R5339 T22595 T22589 prep in,diminished
R5340 T22596 T22597 npadvmod insulin,resistant
R5341 T22597 T22599 amod resistant,muscle
R5342 T22598 T22597 punct -,resistant
R5343 T22599 T22595 pobj muscle,in
R5344 T22600 T22597 cc and,resistant
R5345 T22601 T22597 conj diabetic,resistant
R5346 T22602 T22603 punct [,23
R5347 T22603 T22589 parataxis 23,diminished
R5348 T22604 T22603 nummod 22,23
R5349 T22605 T22603 punct ",",23
R5350 T22606 T22603 punct ],23
R5351 T22607 T22561 punct .,suggested
R5352 T22609 T22610 advmod Accordingly,examined
R5353 T22611 T22610 punct ", ",examined
R5354 T22612 T22613 amod peripheral,disposal
R5355 T22613 T22610 nsubjpass disposal,examined
R5356 T22614 T22613 compound glucose,disposal
R5357 T22615 T22613 cc and,disposal
R5358 T22616 T22617 compound insulin,responsiveness
R5359 T22617 T22613 conj responsiveness,disposal
R5360 T22618 T22610 auxpass were,examined
R5361 T22619 T22610 prep in,examined
R5362 T22620 T22621 nmod PGC,1α
R5363 T22621 T22623 nmod 1α,mice
R5364 T22622 T22621 punct -,1α
R5365 T22623 T22619 pobj mice,in
R5366 T22624 T22621 punct −,1α
R5367 T22625 T22621 punct /,1α
R5368 T22626 T22621 punct −,1α
R5369 T22627 T22610 punct .,examined
R5370 T22629 T22630 compound Glucose,tolerance
R5371 T22630 T22631 compound tolerance,testing
R5372 T22631 T22632 nsubj testing,revealed
R5373 T22633 T22631 prep of,testing
R5374 T22634 T22635 nummod 2,mo
R5375 T22635 T22637 npadvmod mo,old
R5376 T22636 T22635 punct -,mo
R5377 T22637 T22639 amod old,mice
R5378 T22638 T22637 punct -,old
R5379 T22639 T22633 pobj mice,of
R5380 T22640 T22639 amod male,mice
R5381 T22641 T22640 cc and,male
R5382 T22642 T22640 conj female,male
R5383 T22643 T22644 det no,difference
R5384 T22644 T22632 dobj difference,revealed
R5385 T22645 T22644 amod significant,difference
R5386 T22646 T22644 prep in,difference
R5387 T22647 T22648 compound blood,glucose
R5388 T22648 T22649 compound glucose,excursion
R5389 T22649 T22646 pobj excursion,in
R5390 T22650 T22644 prep between,difference
R5391 T22651 T22652 nmod PGC,1α
R5392 T22652 T22654 nmod 1α,groups
R5393 T22653 T22652 punct -,1α
R5394 T22654 T22650 pobj groups,between
R5395 T22655 T22652 punct +,1α
R5396 T22656 T22652 punct /,1α
R5397 T22657 T22652 punct +,1α
R5398 T22658 T22652 cc and,1α
R5399 T22659 T22660 compound PGC,1α
R5400 T22660 T22652 conj 1α,1α
R5401 T22661 T22660 punct -,1α
R5402 T22662 T22660 punct −,1α
R5403 T22663 T22660 punct /,1α
R5404 T22664 T22660 punct −,1α
R5405 T22665 T22666 punct (,data
R5406 T22666 T22632 meta data,revealed
R5407 T22667 T22666 amod unpublished,data
R5408 T22668 T22666 punct ),data
R5409 T22669 T22632 punct .,revealed
R5410 T22671 T22672 prep Given,evaluated
R5411 T22673 T22674 mark that,develop
R5412 T22674 T22671 pcomp develop,Given
R5413 T22675 T22676 amod older,mice
R5414 T22676 T22674 nsubj mice,develop
R5415 T22677 T22676 amod female,mice
R5416 T22678 T22679 nmod PGC,1α
R5417 T22679 T22676 nmod 1α,mice
R5418 T22680 T22679 punct -,1α
R5419 T22681 T22679 punct −,1α
R5420 T22682 T22679 punct /,1α
R5421 T22683 T22679 punct −,1α
R5422 T22684 T22685 det an,increase
R5423 T22685 T22674 dobj increase,develop
R5424 T22686 T22685 prep in,increase
R5425 T22687 T22688 compound body,fat
R5426 T22688 T22689 compound fat,stores
R5427 T22689 T22686 pobj stores,in
R5428 T22690 T22672 punct ", ",evaluated
R5429 T22691 T22692 compound glucose,tolerance
R5430 T22692 T22672 nsubjpass tolerance,evaluated
R5431 T22693 T22692 cc and,tolerance
R5432 T22694 T22695 compound insulin,responsiveness
R5433 T22695 T22692 conj responsiveness,tolerance
R5434 T22696 T22672 auxpass were,evaluated
R5435 T22697 T22672 advmod further,evaluated
R5436 T22698 T22672 prep in,evaluated
R5437 T22699 T22700 det this,group
R5438 T22700 T22698 pobj group,in
R5439 T22701 T22672 punct .,evaluated
R5440 T22703 T22704 compound Glucose,tolerance
R5441 T22704 T22705 compound tolerance,testing
R5442 T22705 T22706 nsubj testing,revealed
R5443 T22707 T22705 prep in,testing
R5444 T22708 T22709 nummod 4.5,mo
R5445 T22709 T22711 npadvmod mo,old
R5446 T22710 T22709 punct -,mo
R5447 T22711 T22713 amod old,mice
R5448 T22712 T22711 punct -,old
R5449 T22713 T22707 pobj mice,in
R5450 T22714 T22713 amod female,mice
R5451 T22715 T22716 nmod PGC,1α
R5452 T22716 T22713 nmod 1α,mice
R5453 T22717 T22716 punct -,1α
R5454 T22718 T22716 punct −,1α
R5455 T22719 T22716 punct /,1α
R5456 T22720 T22716 punct −,1α
R5457 T22721 T22722 mark that,exhibited
R5458 T22722 T22706 ccomp exhibited,revealed
R5459 T22723 T22722 punct ", ",exhibited
R5460 T22724 T22722 prep despite,exhibited
R5461 T22725 T22726 amod increased,weight
R5462 T22726 T22724 pobj weight,despite
R5463 T22727 T22726 compound body,weight
R5464 T22728 T22729 punct [,g
R5465 T22729 T22726 parataxis g,weight
R5466 T22730 T22731 nmod mean,weight
R5467 T22731 T22741 nsubj weight,g
R5468 T22732 T22730 punct ±,mean
R5469 T22733 T22734 amod standard,error
R5470 T22734 T22730 appos error,mean
R5471 T22735 T22734 prep of,error
R5472 T22736 T22737 det the,mean
R5473 T22737 T22735 pobj mean,of
R5474 T22738 T22734 punct (,error
R5475 T22739 T22734 appos SEM,error
R5476 T22740 T22731 punct ),weight
R5477 T22741 T22729 ccomp g,g
R5478 T22742 T22731 prep of,weight
R5479 T22743 T22744 nmod PGC,1α
R5480 T22744 T22746 nmod 1α,mice
R5481 T22745 T22743 punct -,PGC
R5482 T22746 T22742 pobj mice,of
R5483 T22747 T22744 punct +,1α
R5484 T22748 T22744 punct /,1α
R5485 T22749 T22744 punct +,1α
R5486 T22750 T22741 punct =,g
R5487 T22751 T22752 quantmod 22.4,0.79
R5488 T22752 T22741 nummod 0.79,g
R5489 T22753 T22752 punct ±,0.79
R5490 T22754 T22729 punct ;,g
R5491 T22755 T22756 nmod PGC,1α
R5492 T22756 T22758 nmod 1α,mice
R5493 T22757 T22756 punct -,1α
R5494 T22758 T22729 dep mice,g
R5495 T22759 T22756 punct −,1α
R5496 T22760 T22756 punct /,1α
R5497 T22761 T22756 punct −,1α
R5498 T22762 T22729 punct =,g
R5499 T22763 T22764 quantmod 25.2,1.04
R5500 T22764 T22729 nummod 1.04,g
R5501 T22765 T22764 punct ±,1.04
R5502 T22766 T22722 punct ),exhibited
R5503 T22767 T22722 punct ", ",exhibited
R5504 T22768 T22769 nmod PGC,1α
R5505 T22769 T22771 nmod 1α,mice
R5506 T22770 T22769 punct -,1α
R5507 T22771 T22722 nsubj mice,exhibited
R5508 T22772 T22769 punct −,1α
R5509 T22773 T22769 punct /,1α
R5510 T22774 T22769 punct −,1α
R5511 T22775 T22776 amod similar,levels
R5512 T22776 T22722 dobj levels,exhibited
R5513 T22777 T22776 prep of,levels
R5514 T22778 T22779 compound glucose,tolerance
R5515 T22779 T22777 pobj tolerance,of
R5516 T22780 T22776 prep compared,levels
R5517 T22781 T22780 prep to,compared
R5518 T22782 T22783 compound WT,mice
R5519 T22783 T22781 pobj mice,to
R5520 T22784 T22783 prep on,mice
R5521 T22785 T22786 amod standard,chow
R5522 T22786 T22784 pobj chow,on
R5523 T22787 T22786 compound rodent,chow
R5524 T22788 T22789 punct (,Figure
R5525 T22789 T22722 parataxis Figure,exhibited
R5526 T22790 T22789 nummod 9,Figure
R5527 T22791 T22789 punct ),Figure
R5528 T22792 T22706 punct .,revealed
R5529 T22794 T22795 aux To,examine
R5530 T22795 T22796 advcl examine,placed
R5531 T22797 T22798 compound glucose,homeostasis
R5532 T22798 T22795 dobj homeostasis,examine
R5533 T22799 T22798 prep in,homeostasis
R5534 T22800 T22799 pobj response,in
R5535 T22801 T22800 prep to,response
R5536 T22802 T22803 amod high,fat
R5537 T22803 T22805 compound fat,diet
R5538 T22804 T22803 punct -,fat
R5539 T22805 T22801 pobj diet,to
R5540 T22806 T22796 punct ", ",placed
R5541 T22807 T22808 amod female,mice
R5542 T22808 T22796 nsubjpass mice,placed
R5543 T22809 T22810 nmod PGC,1α
R5544 T22810 T22808 nmod 1α,mice
R5545 T22811 T22810 punct -,1α
R5546 T22812 T22810 punct +,1α
R5547 T22813 T22810 punct /,1α
R5548 T22814 T22810 punct +,1α
R5549 T22815 T22810 cc and,1α
R5550 T22816 T22817 compound PGC,1α
R5551 T22817 T22810 conj 1α,1α
R5552 T22818 T22817 punct -,1α
R5553 T22819 T22817 punct −,1α
R5554 T22820 T22817 punct /,1α
R5555 T22821 T22817 punct −,1α
R5556 T22822 T22796 auxpass were,placed
R5557 T22823 T22796 prep on,placed
R5558 T22824 T22825 amod high,fat
R5559 T22825 T22827 compound fat,chow
R5560 T22826 T22825 punct -,fat
R5561 T22827 T22823 pobj chow,on
R5562 T22828 T22829 punct (,calories
R5563 T22829 T22796 parataxis calories,placed
R5564 T22830 T22831 nummod 43,%
R5565 T22831 T22829 compound %,calories
R5566 T22832 T22829 prep from,calories
R5567 T22833 T22832 pobj fat,from
R5568 T22834 T22829 punct ),calories
R5569 T22835 T22796 prep for,placed
R5570 T22836 T22837 nummod 6,wk
R5571 T22837 T22835 pobj wk,for
R5572 T22838 T22796 advcl starting,placed
R5573 T22839 T22838 prep at,starting
R5574 T22840 T22841 nummod 8,wk
R5575 T22841 T22839 pobj wk,at
R5576 T22842 T22841 prep of,wk
R5577 T22843 T22842 pobj age,of
R5578 T22844 T22796 punct .,placed
R5579 T22846 T22847 det The,weight
R5580 T22847 T22848 nsubj weight,was
R5581 T22849 T22847 acl gained,weight
R5582 T22850 T22849 prep on,gained
R5583 T22851 T22852 det the,diet
R5584 T22852 T22850 pobj diet,on
R5585 T22853 T22854 amod high,fat
R5586 T22854 T22852 compound fat,diet
R5587 T22855 T22854 punct -,fat
R5588 T22856 T22848 acomp similar,was
R5589 T22857 T22848 prep for,was
R5590 T22858 T22859 det the,groups
R5591 T22859 T22857 pobj groups,for
R5592 T22860 T22861 nmod PGC,1α
R5593 T22861 T22859 nmod 1α,groups
R5594 T22862 T22861 punct -,1α
R5595 T22863 T22861 punct +,1α
R5596 T22864 T22861 punct /,1α
R5597 T22865 T22861 punct +,1α
R5598 T22866 T22861 cc and,1α
R5599 T22867 T22868 compound PGC,1α
R5600 T22868 T22861 conj 1α,1α
R5601 T22869 T22868 punct -,1α
R5602 T22870 T22868 punct −,1α
R5603 T22871 T22868 punct /,1α
R5604 T22872 T22868 punct −,1α
R5605 T22873 T22874 punct (,S3
R5606 T22874 T22848 parataxis S3,was
R5607 T22875 T22874 compound Figure,S3
R5608 T22876 T22874 punct ),S3
R5609 T22877 T22848 punct .,was
R5610 T22879 T22880 advmod Surprisingly,were
R5611 T22881 T22880 punct ", ",were
R5612 T22882 T22883 det the,mice
R5613 T22883 T22880 nsubj mice,were
R5614 T22884 T22885 nmod PGC,1α
R5615 T22885 T22883 nmod 1α,mice
R5616 T22886 T22885 punct -,1α
R5617 T22887 T22885 punct −,1α
R5618 T22888 T22885 punct /,1α
R5619 T22889 T22885 punct −,1α
R5620 T22890 T22883 prep on,mice
R5621 T22891 T22892 det a,diet
R5622 T22892 T22890 pobj diet,on
R5623 T22893 T22894 amod high,fat
R5624 T22894 T22892 compound fat,diet
R5625 T22895 T22894 punct -,fat
R5626 T22896 T22897 advmod significantly,more
R5627 T22897 T22898 advmod more,tolerant
R5628 T22898 T22880 acomp tolerant,were
R5629 T22899 T22898 npadvmod glucose,tolerant
R5630 T22900 T22898 punct -,tolerant
R5631 T22901 T22898 cc and,tolerant
R5632 T22902 T22903 npadvmod insulin,sensitive
R5633 T22903 T22898 conj sensitive,tolerant
R5634 T22904 T22903 punct -,sensitive
R5635 T22905 T22880 prep compared,were
R5636 T22906 T22905 prep to,compared
R5637 T22907 T22908 det the,mice
R5638 T22908 T22906 pobj mice,to
R5639 T22909 T22910 nmod PGC,1α
R5640 T22910 T22908 nmod 1α,mice
R5641 T22911 T22910 punct -,1α
R5642 T22912 T22910 punct +,1α
R5643 T22913 T22910 punct /,1α
R5644 T22914 T22910 punct +,1α
R5645 T22915 T22916 punct (,9B
R5646 T22916 T22880 parataxis 9B,were
R5647 T22917 T22916 compound Figure,9B
R5648 T22918 T22916 punct ),9B
R5649 T22919 T22880 punct .,were
R5650 T22921 T22922 advcl Taken,indicate
R5651 T22923 T22921 advmod together,Taken
R5652 T22924 T22922 punct ", ",indicate
R5653 T22925 T22926 det these,results
R5654 T22926 T22922 nsubj results,indicate
R5655 T22927 T22928 mark that,exhibit
R5656 T22928 T22922 ccomp exhibit,indicate
R5657 T22929 T22928 punct ", ",exhibit
R5658 T22930 T22928 prep despite,exhibit
R5659 T22931 T22932 amod excess,fat
R5660 T22932 T22930 pobj fat,despite
R5661 T22933 T22932 compound body,fat
R5662 T22934 T22932 prep under,fat
R5663 T22935 T22936 amod standard,conditions
R5664 T22936 T22934 pobj conditions,under
R5665 T22937 T22928 punct ", ",exhibit
R5666 T22938 T22939 det the,mice
R5667 T22939 T22928 nsubj mice,exhibit
R5668 T22940 T22939 amod female,mice
R5669 T22941 T22942 nmod PGC,1α
R5670 T22942 T22939 nmod 1α,mice
R5671 T22943 T22942 punct -,1α
R5672 T22944 T22942 punct −,1α
R5673 T22945 T22942 punct /,1α
R5674 T22946 T22942 punct −,1α
R5675 T22947 T22928 aux do,exhibit
R5676 T22948 T22928 neg not,exhibit
R5677 T22949 T22950 compound insulin,resistance
R5678 T22950 T22928 dobj resistance,exhibit
R5679 T22951 T22922 punct .,indicate
R5680 T22953 T22954 advmod Moreover,are
R5681 T22955 T22954 punct ", ",are
R5682 T22956 T22957 det the,mice
R5683 T22957 T22954 nsubj mice,are
R5684 T22958 T22959 nmod PGC,1α
R5685 T22959 T22957 nmod 1α,mice
R5686 T22960 T22959 punct -,1α
R5687 T22961 T22959 punct −,1α
R5688 T22962 T22959 punct /,1α
R5689 T22963 T22959 punct −,1α
R5690 T22964 T22965 advmod more,tolerant
R5691 T22965 T22954 acomp tolerant,are
R5692 T22966 T22965 npadvmod glucose,tolerant
R5693 T22967 T22965 punct -,tolerant
R5694 T22968 T22965 cc and,tolerant
R5695 T22969 T22970 npadvmod insulin,sensitive
R5696 T22970 T22965 conj sensitive,tolerant
R5697 T22971 T22970 punct -,sensitive
R5698 T22972 T22965 prep than,tolerant
R5699 T22973 T22974 compound WT,mice
R5700 T22974 T22972 pobj mice,than
R5701 T22975 T22974 prep on,mice
R5702 T22976 T22977 det a,diet
R5703 T22977 T22975 pobj diet,on
R5704 T22978 T22979 amod high,fat
R5705 T22979 T22977 compound fat,diet
R5706 T22980 T22979 punct -,fat
R5707 T22981 T22954 punct .,are