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PMC:1064854 / 27935-28713 JSONTXT 7 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T17380 0-3 NN denotes PGC
T17382 3-4 HYPH denotes -
T17381 4-6 NN denotes 1α
T17384 7-10 VBZ denotes has
T17385 11-15 VBN denotes been
T17383 16-26 VBN denotes implicated
T17386 27-29 IN denotes as
T17387 30-32 DT denotes an
T17389 33-42 JJ denotes inducible
T17388 43-52 NN denotes regulator
T17390 53-55 IN denotes of
T17391 56-69 JJ denotes mitochondrial
T17393 70-81 JJ denotes respiratory
T17392 82-92 NN denotes uncoupling
T17394 92-94 , denotes ,
T17395 94-96 DT denotes an
T17397 97-106 JJ denotes important
T17396 107-113 NN denotes source
T17398 114-116 IN denotes of
T17399 117-121 NN denotes heat
T17400 122-132 NN denotes production
T17401 133-135 IN denotes in
T17402 136-139 NN denotes BAT
T17403 140-141 -LRB- denotes [
T17404 141-142 CD denotes 2
T17405 142-143 -RRB- denotes ]
T17406 143-144 . denotes .
T17407 144-354 sentence denotes To determine whether PGC-1α is necessary for an appropriate thermogenic response, PGC-1α+/+ and PGC-1α−/− mice were subjected to cold exposure (4 °C) for a 5-h period while core body temperature was monitored.
T17408 145-147 TO denotes To
T17409 148-157 VB denotes determine
T17411 158-165 IN denotes whether
T17413 166-169 NN denotes PGC
T17415 169-170 HYPH denotes -
T17414 170-172 NN denotes 1α
T17412 173-175 VBZ denotes is
T17416 176-185 JJ denotes necessary
T17417 186-189 IN denotes for
T17418 190-192 DT denotes an
T17420 193-204 JJ denotes appropriate
T17421 205-216 JJ denotes thermogenic
T17419 217-225 NN denotes response
T17422 225-227 , denotes ,
T17423 227-230 NN denotes PGC
T17425 230-231 HYPH denotes -
T17424 231-233 NN denotes 1α
T17427 233-234 SYM denotes +
T17428 234-235 HYPH denotes /
T17429 235-236 SYM denotes +
T17430 237-240 CC denotes and
T17431 241-244 NN denotes PGC
T17433 244-245 HYPH denotes -
T17432 245-247 NN denotes 1α
T17434 247-248 SYM denotes −
T17435 248-249 HYPH denotes /
T17436 249-250 SYM denotes −
T17426 251-255 NNS denotes mice
T17437 256-260 VBD denotes were
T17410 261-270 VBN denotes subjected
T17438 271-273 IN denotes to
T17439 274-278 NN denotes cold
T17440 279-287 NN denotes exposure
T17441 288-289 -LRB- denotes (
T17443 289-290 CD denotes 4
T17442 291-293 NN denotes °C
T17444 293-294 -RRB- denotes )
T17445 295-298 IN denotes for
T17446 299-300 DT denotes a
T17448 301-302 CD denotes 5
T17450 302-303 HYPH denotes -
T17449 303-304 NN denotes h
T17447 305-311 NN denotes period
T17451 312-317 IN denotes while
T17453 318-322 NN denotes core
T17455 323-327 NN denotes body
T17454 328-339 NN denotes temperature
T17456 340-343 VBD denotes was
T17452 344-353 VBN denotes monitored
T17457 353-354 . denotes .
T17458 354-465 sentence denotes PGC-1α−/− mice exhibited a markedly abnormal drop in core temperature compared to the WT controls (Figure 6A).
T17459 355-358 NN denotes PGC
T17461 358-359 HYPH denotes -
T17460 359-361 NN denotes 1α
T17463 361-362 SYM denotes −
T17464 362-363 HYPH denotes /
T17465 363-364 SYM denotes −
T17462 365-369 NNS denotes mice
T17466 370-379 VBD denotes exhibited
T17467 380-381 DT denotes a
T17469 382-390 RB denotes markedly
T17470 391-399 JJ denotes abnormal
T17468 400-404 NN denotes drop
T17471 405-407 IN denotes in
T17472 408-412 NN denotes core
T17473 413-424 NN denotes temperature
T17474 425-433 VBN denotes compared
T17475 434-436 IN denotes to
T17476 437-440 DT denotes the
T17478 441-443 NN denotes WT
T17477 444-452 NNS denotes controls
T17479 453-454 -LRB- denotes (
T17481 454-460 NN denotes Figure
T17480 461-463 NN denotes 6A
T17482 463-464 -RRB- denotes )
T17483 464-465 . denotes .
T17484 465-647 sentence denotes Specifically, the mean decline in core temperature was greater than 12 °C at the 5-h time point in PGC-1α−/− mice, compared to an approximately 3 °C decrement in PGC-1α+/+ controls.
T17485 466-478 RB denotes Specifically
T17487 478-480 , denotes ,
T17488 480-483 DT denotes the
T17490 484-488 NN denotes mean
T17489 489-496 NN denotes decline
T17491 497-499 IN denotes in
T17492 500-504 NN denotes core
T17493 505-516 NN denotes temperature
T17486 517-520 VBD denotes was
T17494 521-528 JJR denotes greater
T17495 529-533 IN denotes than
T17496 534-536 CD denotes 12
T17497 537-539 NN denotes °C
T17498 540-542 IN denotes at
T17499 543-546 DT denotes the
T17501 547-548 CD denotes 5
T17503 548-549 HYPH denotes -
T17502 549-550 NN denotes h
T17504 551-555 NN denotes time
T17500 556-561 NN denotes point
T17505 562-564 IN denotes in
T17506 565-568 NN denotes PGC
T17508 568-569 HYPH denotes -
T17507 569-571 NN denotes 1α
T17510 571-572 SYM denotes −
T17511 572-573 HYPH denotes /
T17512 573-574 SYM denotes −
T17509 575-579 NNS denotes mice
T17513 579-581 , denotes ,
T17514 581-589 VBN denotes compared
T17515 590-592 IN denotes to
T17516 593-595 DT denotes an
T17518 596-609 RB denotes approximately
T17519 610-611 CD denotes 3
T17520 612-614 NN denotes °C
T17517 615-624 NN denotes decrement
T17521 625-627 IN denotes in
T17522 628-631 NN denotes PGC
T17524 631-632 HYPH denotes -
T17523 632-634 NN denotes 1α
T17526 634-635 SYM denotes +
T17527 635-636 HYPH denotes /
T17528 636-637 SYM denotes +
T17525 638-646 NNS denotes controls
T17529 646-647 . denotes .
T17530 647-778 sentence denotes Although this thermogenic phenotype was consistently present in mice aged 28–37 d, it was absent in older mice (unpublished data).
T17531 648-656 IN denotes Although
T17533 657-661 DT denotes this
T17535 662-673 JJ denotes thermogenic
T17534 674-683 NN denotes phenotype
T17532 684-687 VBD denotes was
T17537 688-700 RB denotes consistently
T17538 701-708 JJ denotes present
T17539 709-711 IN denotes in
T17540 712-716 NNS denotes mice
T17541 717-721 VBN denotes aged
T17542 722-724 CD denotes 28
T17544 724-725 SYM denotes –
T17543 725-727 CD denotes 37
T17545 728-729 NN denotes d
T17546 729-731 , denotes ,
T17547 731-733 PRP denotes it
T17536 734-737 VBD denotes was
T17548 738-744 JJ denotes absent
T17549 745-747 IN denotes in
T17550 748-753 JJR denotes older
T17551 754-758 NNS denotes mice
T17552 759-760 -LRB- denotes (
T17554 760-771 JJ denotes unpublished
T17553 772-776 NNS denotes data
T17555 776-777 -RRB- denotes )
T17556 777-778 . denotes .
R4020 T17380 T17381 compound PGC,1α
R4021 T17381 T17383 nsubjpass 1α,implicated
R4022 T17382 T17381 punct -,1α
R4023 T17384 T17383 aux has,implicated
R4024 T17385 T17383 auxpass been,implicated
R4025 T17386 T17383 prep as,implicated
R4026 T17387 T17388 det an,regulator
R4027 T17388 T17386 pobj regulator,as
R4028 T17389 T17388 amod inducible,regulator
R4029 T17390 T17388 prep of,regulator
R4030 T17391 T17392 amod mitochondrial,uncoupling
R4031 T17392 T17390 pobj uncoupling,of
R4032 T17393 T17392 amod respiratory,uncoupling
R4033 T17394 T17392 punct ", ",uncoupling
R4034 T17395 T17396 det an,source
R4035 T17396 T17392 appos source,uncoupling
R4036 T17397 T17396 amod important,source
R4037 T17398 T17396 prep of,source
R4038 T17399 T17400 compound heat,production
R4039 T17400 T17398 pobj production,of
R4040 T17401 T17396 prep in,source
R4041 T17402 T17401 pobj BAT,in
R4042 T17403 T17404 punct [,2
R4043 T17404 T17383 parataxis 2,implicated
R4044 T17405 T17404 punct ],2
R4045 T17406 T17383 punct .,implicated
R4046 T17408 T17409 aux To,determine
R4047 T17409 T17410 advcl determine,subjected
R4048 T17411 T17412 mark whether,is
R4049 T17412 T17409 ccomp is,determine
R4050 T17413 T17414 compound PGC,1α
R4051 T17414 T17412 nsubj 1α,is
R4052 T17415 T17414 punct -,1α
R4053 T17416 T17412 acomp necessary,is
R4054 T17417 T17416 prep for,necessary
R4055 T17418 T17419 det an,response
R4056 T17419 T17417 pobj response,for
R4057 T17420 T17419 amod appropriate,response
R4058 T17421 T17419 amod thermogenic,response
R4059 T17422 T17410 punct ", ",subjected
R4060 T17423 T17424 nmod PGC,1α
R4061 T17424 T17426 nmod 1α,mice
R4062 T17425 T17424 punct -,1α
R4063 T17426 T17410 nsubjpass mice,subjected
R4064 T17427 T17424 punct +,1α
R4065 T17428 T17424 punct /,1α
R4066 T17429 T17424 punct +,1α
R4067 T17430 T17424 cc and,1α
R4068 T17431 T17432 compound PGC,1α
R4069 T17432 T17424 conj 1α,1α
R4070 T17433 T17432 punct -,1α
R4071 T17434 T17432 punct −,1α
R4072 T17435 T17432 punct /,1α
R4073 T17436 T17432 punct −,1α
R4074 T17437 T17410 auxpass were,subjected
R4075 T17438 T17410 prep to,subjected
R4076 T17439 T17440 compound cold,exposure
R4077 T17440 T17438 pobj exposure,to
R4078 T17441 T17442 punct (,°C
R4079 T17442 T17440 parataxis °C,exposure
R4080 T17443 T17442 nummod 4,°C
R4081 T17444 T17442 punct ),°C
R4082 T17445 T17410 prep for,subjected
R4083 T17446 T17447 det a,period
R4084 T17447 T17445 pobj period,for
R4085 T17448 T17449 nummod 5,h
R4086 T17449 T17447 compound h,period
R4087 T17450 T17449 punct -,h
R4088 T17451 T17452 mark while,monitored
R4089 T17452 T17410 advcl monitored,subjected
R4090 T17453 T17454 compound core,temperature
R4091 T17454 T17452 nsubjpass temperature,monitored
R4092 T17455 T17454 compound body,temperature
R4093 T17456 T17452 auxpass was,monitored
R4094 T17457 T17410 punct .,subjected
R4095 T17459 T17460 nmod PGC,1α
R4096 T17460 T17462 nmod 1α,mice
R4097 T17461 T17460 punct -,1α
R4098 T17462 T17466 nsubj mice,exhibited
R4099 T17463 T17460 punct −,1α
R4100 T17464 T17460 punct /,1α
R4101 T17465 T17460 punct −,1α
R4102 T17467 T17468 det a,drop
R4103 T17468 T17466 dobj drop,exhibited
R4104 T17469 T17470 advmod markedly,abnormal
R4105 T17470 T17468 amod abnormal,drop
R4106 T17471 T17468 prep in,drop
R4107 T17472 T17473 compound core,temperature
R4108 T17473 T17471 pobj temperature,in
R4109 T17474 T17466 prep compared,exhibited
R4110 T17475 T17474 prep to,compared
R4111 T17476 T17477 det the,controls
R4112 T17477 T17475 pobj controls,to
R4113 T17478 T17477 compound WT,controls
R4114 T17479 T17480 punct (,6A
R4115 T17480 T17466 parataxis 6A,exhibited
R4116 T17481 T17480 compound Figure,6A
R4117 T17482 T17480 punct ),6A
R4118 T17483 T17466 punct .,exhibited
R4119 T17485 T17486 advmod Specifically,was
R4120 T17487 T17486 punct ", ",was
R4121 T17488 T17489 det the,decline
R4122 T17489 T17486 nsubj decline,was
R4123 T17490 T17489 compound mean,decline
R4124 T17491 T17489 prep in,decline
R4125 T17492 T17493 compound core,temperature
R4126 T17493 T17491 pobj temperature,in
R4127 T17494 T17486 acomp greater,was
R4128 T17495 T17494 prep than,greater
R4129 T17496 T17497 nummod 12,°C
R4130 T17497 T17495 pobj °C,than
R4131 T17498 T17486 prep at,was
R4132 T17499 T17500 det the,point
R4133 T17500 T17498 pobj point,at
R4134 T17501 T17502 nummod 5,h
R4135 T17502 T17500 compound h,point
R4136 T17503 T17502 punct -,h
R4137 T17504 T17500 compound time,point
R4138 T17505 T17486 prep in,was
R4139 T17506 T17507 nmod PGC,1α
R4140 T17507 T17509 nmod 1α,mice
R4141 T17508 T17507 punct -,1α
R4142 T17509 T17505 pobj mice,in
R4143 T17510 T17507 punct −,1α
R4144 T17511 T17507 punct /,1α
R4145 T17512 T17507 punct −,1α
R4146 T17513 T17486 punct ", ",was
R4147 T17514 T17486 prep compared,was
R4148 T17515 T17514 prep to,compared
R4149 T17516 T17517 det an,decrement
R4150 T17517 T17515 pobj decrement,to
R4151 T17518 T17519 advmod approximately,3
R4152 T17519 T17520 nummod 3,°C
R4153 T17520 T17517 compound °C,decrement
R4154 T17521 T17517 prep in,decrement
R4155 T17522 T17523 nmod PGC,1α
R4156 T17523 T17525 nmod 1α,controls
R4157 T17524 T17523 punct -,1α
R4158 T17525 T17521 pobj controls,in
R4159 T17526 T17523 punct +,1α
R4160 T17527 T17523 punct /,1α
R4161 T17528 T17523 punct +,1α
R4162 T17529 T17486 punct .,was
R4163 T17531 T17532 mark Although,was
R4164 T17532 T17536 advcl was,was
R4165 T17533 T17534 det this,phenotype
R4166 T17534 T17532 nsubj phenotype,was
R4167 T17535 T17534 amod thermogenic,phenotype
R4168 T17537 T17532 advmod consistently,was
R4169 T17538 T17532 acomp present,was
R4170 T17539 T17532 prep in,was
R4171 T17540 T17539 pobj mice,in
R4172 T17541 T17540 amod aged,mice
R4173 T17542 T17543 quantmod 28,37
R4174 T17543 T17545 nummod 37,d
R4175 T17544 T17543 punct –,37
R4176 T17545 T17541 npadvmod d,aged
R4177 T17546 T17536 punct ", ",was
R4178 T17547 T17536 nsubj it,was
R4179 T17548 T17536 acomp absent,was
R4180 T17549 T17536 prep in,was
R4181 T17550 T17551 amod older,mice
R4182 T17551 T17549 pobj mice,in
R4183 T17552 T17553 punct (,data
R4184 T17553 T17536 meta data,was
R4185 T17554 T17553 amod unpublished,data
R4186 T17555 T17553 punct ),data
R4187 T17556 T17536 punct .,was