Id |
Subject |
Object |
Predicate |
Lexical cue |
T1 |
18-22 |
Protein |
denotes |
APC2 |
T2 |
43-87 |
Protein |
denotes |
adenomatous polyposis coli tumour suppressor |
T3 |
93-151 |
Protein |
denotes |
adenomatous polyposis coli (APC) tumour-suppressor protein |
E3 |
152-160 |
RegulatoryProcess |
denotes |
controls |
T8 |
165-168 |
Protein |
denotes |
Wnt |
E4 |
169-187 |
SignalingPathway |
denotes |
signalling pathway |
T11 |
201-208 |
ProteinComplex |
denotes |
complex |
T13 |
246-255 |
Enzyme |
denotes |
GSK-3beta |
T14 |
258-272 |
Protein |
denotes |
axin/conductin |
T15 |
277-288 |
Protein |
denotes |
betacatenin |
T16 |
290-297 |
ProteinComplex |
denotes |
Complex |
E7 |
308-315 |
PositiveRegulation |
denotes |
induces |
E8 |
326-337 |
ProteinCatabolism |
denotes |
degradation |
T20 |
341-352 |
Protein |
denotes |
betacatenin |
T4 |
357-372 |
Tissue |
denotes |
colon carcinoma |
T5 |
373-378 |
Cell |
denotes |
cells |
E9 |
380-384 |
Decrease |
denotes |
loss |
T23 |
388-391 |
Protein |
denotes |
APC |
E1 |
392-397 |
PositiveRegulation |
denotes |
leads |
E10 |
405-417 |
Increase |
denotes |
accumulation |
T25 |
421-432 |
Protein |
denotes |
betacatenin |
T26 |
440-447 |
Nucleus |
denotes |
nucleus |
E11 |
458-463 |
BindingToProtein |
denotes |
binds |
E12 |
471-480 |
PositiveRegulation |
denotes |
activates |
T17 |
485-511 |
TranscriptionFactor |
denotes |
Tcf-4 transcription factor |
T31 |
595-598 |
Protein |
denotes |
APC |
T32 |
611-620 |
Eukaryote |
denotes |
Mammalian |
T33 |
621-625 |
Protein |
denotes |
APC2 |
T34 |
651-654 |
Protein |
denotes |
APC |
T35 |
666-682 |
ProteinDomain |
denotes |
domain structure |
T36 |
735-747 |
ProteinDomain |
denotes |
SAMP domains |
E13 |
780-787 |
BindingToProtein |
denotes |
binding |
T38 |
791-800 |
Protein |
denotes |
conductin |
T39 |
807-810 |
Protein |
denotes |
APC |
T40 |
812-816 |
Protein |
denotes |
APC2 |
E14 |
817-826 |
RegulatoryProcess |
denotes |
regulates |
E15 |
831-840 |
FormationOfTranscriptionFactorComplex |
denotes |
formation |
T43 |
851-862 |
Protein |
denotes |
betacatenin |
T44 |
863-866 |
Protein |
denotes |
Tcf |
T45 |
867-876 |
ProteinComplex |
denotes |
complexes |
E16 |
910-925 |
Transcription |
denotes |
transcriptional |
E17 |
926-936 |
PositiveRegulation |
denotes |
activation |
T55 |
937-943 |
ExperimentalMethod |
denotes |
assays |
T48 |
947-950 |
Protein |
denotes |
APC |
T6 |
955-970 |
Tissue |
denotes |
colon carcinoma |
T21 |
971-976 |
Cell |
denotes |
cells |
T50 |
978-983 |
Eukaryote |
denotes |
Human |
T51 |
984-988 |
Protein |
denotes |
APC2 |
T52 |
997-1015 |
Chromosome |
denotes |
chromosome 19p13.3 |
T53 |
1017-1020 |
Protein |
denotes |
APC |
T54 |
1025-1029 |
Protein |
denotes |
APC2 |
T49 |
1060-1069 |
Function |
denotes |
functions |
E18 |
1073-1084 |
DevelopmentalProcess |
denotes |
development |
E19 |
1089-1095 |
Disease |
denotes |
cancer |
R1 |
T33 |
T36 |
hasPart |
APC2,SAMP domains |
R10 |
T45 |
T44 |
hasPart |
complexes,Tcf |
R11 |
T21 |
T6 |
locatedIn |
cells,colon carcinoma |
R12 |
T51 |
T52 |
locatedIn |
APC2,chromosome 19p13.3 |
R13 |
T51 |
T50 |
fromSpecies |
APC2,Human |
R14 |
T54 |
T49 |
hasFunction |
APC2,functions |
R15 |
T53 |
T49 |
hasFunction |
APC,functions |
R16 |
T11 |
T13 |
hasPart |
complex,GSK-3beta |
R17 |
E9 |
T5 |
locatedIn |
loss,cells |
R18 |
T3 |
E3 |
hasAgent |
adenomatous polyposis coli (APC) tumour-suppressor protein,controls |
R19 |
E4 |
E3 |
hasPatient |
signalling pathway,controls |
R20 |
T16 |
E7 |
hasAgent |
Complex,induces |
R21 |
E8 |
E7 |
hasPatient |
degradation,induces |
R22 |
T20 |
E8 |
hasPatient |
betacatenin,degradation |
R23 |
T48 |
T21 |
locatedIn |
APC,cells |
R23 |
T23 |
E9 |
hasPatient |
APC,loss |
R24 |
T25 |
E10 |
hasPatient |
betacatenin,accumulation |
R25 |
T17 |
E11 |
hasPatient |
Tcf-4 transcription factor,binds |
R26 |
T17 |
E12 |
hasPatient |
Tcf-4 transcription factor,activates |
R28 |
T38 |
E13 |
hasPatient |
conductin,binding |
R29 |
T40 |
E14 |
hasAgent |
APC2,regulates |
R3 |
T11 |
T14 |
hasPart |
complex,axin/conductin |
R30 |
E15 |
E14 |
hasPatient |
formation,regulates |
R31 |
T45 |
E15 |
hasPatient |
complexes,formation |
R32 |
E16 |
E17 |
hasPatient |
transcriptional,activation |
R33 |
E9 |
E1 |
hasAgent |
loss,leads |
R34 |
E10 |
E1 |
hasPatient |
accumulation,leads |
R4 |
T11 |
T15 |
hasPart |
complex,betacatenin |
R5 |
T5 |
T4 |
locatedIn |
cells,colon carcinoma |
R6 |
T11 |
T3 |
hasPart |
complex,adenomatous polyposis coli (APC) tumour-suppressor protein |
R7 |
E10 |
T26 |
locatedIn |
accumulation,nucleus |
R8 |
T33 |
T32 |
fromSpecies |
APC2,Mammalian |
R9 |
T45 |
T43 |
hasPart |
complexes,betacatenin |