PMC:3586680 JSONTXT 30 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T474 6-21 Protein denotes Suppressor WWOX
T475 26-29 Protein denotes p53
T476 106-109 Protein denotes p53
T477 273-292 Protein denotes oxidoreductase WWOX
T478 294-297 Protein denotes FOR
T479 301-305 Protein denotes WOX1
T482 374-378 Negative_regulation denotes Loss
T480 382-391 Protein denotes WWOX gene
T481 392-402 Gene_expression denotes expression
T483 521-529 Negative_regulation denotes blockade
T485 553-563 Gene_expression denotes expression
T484 572-581 Protein denotes type WWOX
T486 665-669 Protein denotes WWOX
T489 693-697 Binding denotes bind
T488 693-697 Binding denotes bind
T487 722-725 Protein denotes p53
T490 785-788 Protein denotes p53
T491 793-797 Protein denotes WWOX
T492 859-862 Protein denotes p53
T494 877-885 Regulation denotes modulate
T493 912-916 Protein denotes WWOX
T495 988-991 Protein denotes p53
T496 1003-1013 Negative_regulation denotes deficiency
T2271 1993-2000 Protein denotes histone
T2272 2051-2063 Protein denotes STAT3 kinase
T2274 2514-2524 Negative_regulation denotes inhibition
T2273 2528-2547 Protein denotes antiapoptotic Bcl-2
T2275 3118-3156 Protein denotes O6-methylguanine-DNA methyltransferase
T2276 3158-3162 Protein denotes MGMT
T2277 3260-3264 Protein denotes MGMT
T2279 3300-3310 Positive_regulation denotes activation
T2278 3358-3385 Protein denotes Rad3-related protein kinase
T2281 3506-3516 Gene_expression denotes expression
T2280 3520-3524 Protein denotes MGMT
T2282 3528-3532 Negative_regulation denotes loss
T2283 3829-3847 Protein denotes MGMT gene promoter
T2286 3914-3922 Positive_regulation denotes increase
T2284 3926-3930 Protein denotes MGMT
T2288 3964-3970 Negative_regulation denotes blocks
T2285 3971-3983 Protein denotes MGMT protein
T2287 3984-3994 Gene_expression denotes expression
T2294 4070-4077 Negative_regulation denotes reduces
T2293 4070-4077 Negative_regulation denotes reduces
T2292 4070-4077 Negative_regulation denotes reduces
T2289 4078-4081 Protein denotes Bax
T2290 4082-4087 Protein denotes Bcl-2
T2291 4098-4107 Protein denotes caspase-3
T2295 4358-4371 Protein denotes α5β1 integrin
T2296 4393-4396 Protein denotes p53
T2297 4487-4500 Protein denotes α5β1 integrin
T2298 4572-4629 Protein denotes base excision repair enzyme alkylpurine-DNA-N-glycosylase
T2299 4631-4635 Protein denotes APNG
T2301 4896-4905 Regulation denotes regulated
T2300 4909-4929 Protein denotes cytochrome c oxidase
T2302 5047-5051 Protein denotes MGMT
T2305 5579-5592 Protein denotes valproic acid
T2303 5594-5597 Protein denotes VAP
T2304 5639-5643 Protein denotes MGMT
T2306 5770-5775 Protein denotes NF-κB
T2307 5818-5823 Protein denotes STAT3
T2311 5824-5833 Negative_regulation denotes inhibitor
T2309 5824-5833 Negative_regulation denotes inhibitor
T2308 5837-5842 Protein denotes STAT3
T2310 5843-5852 Negative_regulation denotes knockdown
T2312 6376-6381 Protein denotes CD133
T2313 6382-6390 Gene_expression denotes positive
T2314 6524-6529 Protein denotes CD133
T5411 6704-6707 Protein denotes p53
T5412 6712-6716 Protein denotes WWOX
T5413 6799-6834 Protein denotes WW domain-containing oxidoreductase
T5414 6845-6849 Protein denotes WWOX
T5415 6851-6854 Protein denotes FOR
T5416 6859-6863 Protein denotes WOX1
T5417 6888-6908 Protein denotes mouse WWOX/Wwox gene
T5418 7024-7036 Protein denotes WWOX protein
T5419 7104-7135 Protein denotes alcohol dehydrogenase/reductase
T5420 7137-7140 Protein denotes SDR
T5421 7300-7304 Protein denotes WWOX
T5422 7376-7386 Protein denotes SDR domain
T5423 7422-7433 Binding denotes interacting
T13497 7575-7579 Protein denotes WWOX
T13498 7641-7672 Protein denotes alcohol dehydrogenase/reductase
T13499 7674-7677 Protein denotes SDR
T13500 7870-7880 Protein denotes SDR domain
T13501 7978-7983 Protein denotes Tyr33
T13502 7988-7994 Protein denotes Tyr287
T13503 8146-8150 Protein denotes WWOX
T13507 8154-8168 Phosphorylation denotes phosphorylated
T13506 8154-8168 Phosphorylation denotes phosphorylated
T13504 8172-8177 Protein denotes Tyr33
T13508 8182-8187 Binding denotes binds
T13505 8188-8191 Protein denotes p53
T13509 8197-8201 Protein denotes WWOX
T13510 8202-8205 Protein denotes p53
T13516 8290-8295 Binding denotes binds
T13515 8290-8295 Binding denotes binds
T13514 8290-8295 Binding denotes binds
T13511 8349-8354 Protein denotes RUNX2
T13512 8356-8361 Protein denotes c-Jun
T13513 8367-8372 Protein denotes ERBB4
T13519 8407-8414 Binding denotes binding
T13518 8407-8414 Binding denotes binding
T13517 8407-8414 Binding denotes binding
T13522 8415-8421 Negative_regulation denotes blocks
T13521 8415-8421 Negative_regulation denotes blocks
T13520 8415-8421 Negative_regulation denotes blocks
T13526 8494-8499 Binding denotes binds
T13523 8500-8503 Protein denotes Tau
T13524 8512-8515 Protein denotes SDR
T13525 8516-8522 Entity denotes domain
T13527 8524-8528 Protein denotes WWOX
T13528 8549-8552 Protein denotes Wnt
T13529 8553-8562 Protein denotes β-catenin
T13531 8581-8588 Binding denotes binding
T13530 8589-8592 Protein denotes Dvl
T13532 8612-8619 Entity denotes nuclear
T13533 8673-8676 Protein denotes MEK
T13534 8677-8681 Protein denotes WWOX
T13535 8787-8791 Protein denotes WWOX
T13538 8795-8804 Binding denotes recruited
T13540 8829-8840 Binding denotes association
T13539 8829-8840 Binding denotes association
T13536 8846-8852 Protein denotes Hyal-2
T13537 8857-8870 Protein denotes phospho-Ezrin
T13541 8910-8916 Protein denotes TGF-β1
T13542 8933-8939 Protein denotes TGF-β1
T13543 8941-8945 Protein denotes WWOX
T13545 8946-8951 Binding denotes binds
T13546 8971-8978 Binding denotes complex
T13547 9022-9031 Positive_regulation denotes enhancing
T13544 9036-9056 Protein denotes SMAD-driven promoter
T13548 9067-9071 Protein denotes Ack1
T13549 9083-9108 Protein denotes Cdc42-associated kinase 1
T13550 9110-9144 Protein denotes Hyal-2, hyaluronoglucosaminidase 2
T13551 9146-9149 Protein denotes CKI
T13552 9151-9164 Protein denotes casein kinase
T13553 9166-9169 Protein denotes GSK
T13554 9171-9195 Protein denotes glycogen synthase kinase
T13555 9197-9200 Protein denotes PKA
T13556 9202-9218 Protein denotes protein kinase A
T5425 9638-9649 Gene_expression denotes Restoration
T5424 9653-9662 Protein denotes WWOX gene
T5426 9663-9671 Negative_regulation denotes prevents
T5427 9815-9824 Protein denotes WW domain
T5428 9828-9832 Protein denotes WWOX
T5436 9837-9845 Binding denotes interact
T5429 9895-9900 Protein denotes AP-2γ
T5430 9902-9905 Protein denotes p73
T5431 9907-9912 Protein denotes ErbB4
T5432 9914-9919 Protein denotes Ezrin
T5433 9921-9927 Protein denotes SIMPLE
T5434 9929-9934 Protein denotes c-Jun
T5435 9936-9941 Protein denotes RUNX4
T5442 10040-10053 Positive_regulation denotes overexpressed
T5441 10040-10053 Gene_expression denotes overexpressed
T5437 10054-10058 Protein denotes WWOX
T5445 10059-10064 Binding denotes binds
T5444 10059-10064 Binding denotes binds
T5443 10059-10064 Binding denotes binds
T5438 10087-10091 Protein denotes AP-2
T5439 10093-10096 Protein denotes p73
T5440 10102-10107 Protein denotes c-Jun
T5446 10500-10504 Protein denotes WWOX
T5447 10552-10557 Binding denotes binds
T5448 10648-10662 Protein denotes Activated WWOX
T5450 10674-10683 Binding denotes interacts
T5451 10736-10746 Positive_regulation denotes stabilizes
T5449 10747-10750 Protein denotes p53
T5452 10807-10811 Protein denotes WWOX
T5455 10812-10817 Binding denotes binds
T5453 10873-10876 Protein denotes Wnt
T5454 10877-10886 Protein denotes β-catenin
T5456 10937-10940 Protein denotes Dvl
T5457 10968-10989 Protein denotes WWOX sequesters Dvl-2
T5458 11041-11044 Protein denotes TCF
T5459 11303-11307 Protein denotes WWOX
T5460 11343-11364 Protein denotes tumor necrosis factor
T5465 11368-11383 Negative_regulation denotes down-regulating
T5464 11368-11383 Negative_regulation denotes down-regulating
T5461 11394-11409 Protein denotes inhibitor Bcl-2
T5462 11414-11420 Protein denotes Bcl-xL
T5466 11425-11438 Positive_regulation denotes up-regulating
T5463 11449-11452 Protein denotes p53
T5467 11481-11485 Protein denotes WWOX
T5468 11527-11530 Protein denotes p53
T5472 11807-11812 Binding denotes binds
T5471 11807-11812 Binding denotes binds
T5469 11813-11816 Protein denotes MEK
T5470 11836-11839 Protein denotes Lin
T5473 11903-11906 Protein denotes MEK
T5474 11907-11911 Protein denotes WWOX
T5477 11924-11931 Positive_regulation denotes induces
T5475 11932-11936 Protein denotes WWOX
T5476 12001-12004 Protein denotes MEK
T5479 12034-12044 Negative_regulation denotes Inhibition
T5478 12048-12051 Protein denotes MEK
T5484 12146-12156 Gene_expression denotes expression
T5480 12160-12164 Protein denotes WWOX
T5481 12187-12199 Protein denotes procaspase-3
T5482 12204-12214 Protein denotes procaspase
T5486 12217-12227 Positive_regulation denotes activation
T5485 12217-12227 Positive_regulation denotes activation
T5483 12240-12252 Protein denotes cytochrome C
T5487 12253-12262 Localization denotes releasing
T5488 12308-12322 Protein denotes Complement C1q
T5491 12323-12330 Positive_regulation denotes induces
T5489 12339-12343 Protein denotes WWOX
T5490 12344-12359 Phosphorylation denotes phosphorylation
T5492 12492-12496 Protein denotes WWOX
T5504 12547-12554 Binding denotes binding
T5503 12547-12554 Binding denotes binding
T5502 12547-12554 Binding denotes binding
T5501 12547-12554 Binding denotes binding
T5500 12547-12554 Binding denotes binding
T5499 12547-12554 Binding denotes binding
T5498 12547-12554 Binding denotes binding
T5497 12547-12554 Binding denotes binding
T5493 12560-12573 Protein denotes hyaluronidase
T5494 12604-12611 Protein denotes Phospho
T5495 12612-12617 Protein denotes Ezrin
T5496 12619-12622 Protein denotes Jin
T5505 12638-12667 Protein denotes Transforming growth factor β1
T5510 12668-12673 Binding denotes binds
T5506 12734-12738 Protein denotes WWOX
T5507 12739-12745 Protein denotes Hyal-2
T5508 12746-12751 Protein denotes Smad4
T5511 12791-12800 Positive_regulation denotes enhancing
T5509 12805-12825 Protein denotes SMAD-driven promoter
T7128 12874-12883 Positive_regulation denotes Activated
T7127 12884-12887 Protein denotes p53
T7129 13016-13019 Protein denotes p53
T7130 13062-13065 Protein denotes p53
T7131 13125-13148 Protein denotes cyclin-dependent kinase
T7132 13159-13162 Protein denotes p21
T7133 13167-13186 Protein denotes microRNA miR34. p53
T7134 13274-13277 Protein denotes FAS
T7136 13283-13293 Negative_regulation denotes inhibiting
T7135 13298-13322 Protein denotes antiapoptotic gene BCL-2
T7137 13348-13351 Protein denotes p53
T7138 13526-13529 Protein denotes p53
T7154 13546-13557 Regulation denotes controlling
T7153 13546-13557 Regulation denotes controlling
T7152 13546-13557 Regulation denotes controlling
T7151 13546-13557 Regulation denotes controlling
T7150 13576-13586 Regulation denotes regulating
T7149 13576-13586 Regulation denotes regulating
T7148 13576-13586 Regulation denotes regulating
T7147 13576-13586 Regulation denotes regulating
T7146 13591-13601 Gene_expression denotes expression
T7145 13591-13601 Gene_expression denotes expression
T7144 13591-13601 Gene_expression denotes expression
T7143 13591-13601 Gene_expression denotes expression
T7139 13605-13626 Protein denotes smooth muscle α-actin
T7140 13649-13663 Protein denotes collagens IIα1
T7141 13668-13672 Protein denotes VIα1
T7142 13674-13677 Protein denotes Sun
T14506 13720-13723 Protein denotes p53
T14507 13728-13732 Protein denotes WWOX
T14508 13760-13775 Protein denotes Full-length p53
T14509 14031-14034 Protein denotes p53
T14510 14095-14099 Protein denotes WWOX
T14511 14104-14107 Protein denotes p53
T14513 14195-14205 Gene_expression denotes expressing
T14512 14206-14230 Protein denotes endogenous wild type p53
T14514 14256-14260 Protein denotes WWOX
T14516 14261-14266 Binding denotes binds
T14515 14296-14299 Protein denotes p53
T14519 14392-14404 Binding denotes interactions
T14517 14413-14432 Protein denotes mutant p53 proteins
T14518 14437-14441 Protein denotes WWOX
T14520 14515-14518 Protein denotes p53
T14521 14519-14529 Gene_expression denotes expressing
T14522 14554-14577 Protein denotes WWOX binds p53 isoforms
T14524 14653-14663 Gene_expression denotes expressing
T14523 14664-14676 Protein denotes p53 isoforms
T7944 14874-14877 Protein denotes p53
T7946 15077-15087 Gene_expression denotes expression
T7945 15091-15103 Protein denotes p53 isoforms
T7947 15161-15185 Protein denotes Full-length p53, Δ133p53
T7948 15191-15195 Protein denotes p53β
T7951 15200-15209 Localization denotes localized
T7950 15200-15209 Localization denotes localized
T7949 15224-15231 Entity denotes nucleus
T7952 15272-15276 Protein denotes p53γ
T7953 15281-15289 Protein denotes Δ133p53β
T7959 15294-15303 Localization denotes localized
T7958 15294-15303 Localization denotes localized
T7957 15294-15303 Localization denotes localized
T7956 15294-15303 Localization denotes localized
T7954 15311-15318 Entity denotes nucleus
T7955 15323-15332 Entity denotes cytoplasm
T7960 15334-15342 Protein denotes Δ133p53γ
T7961 15346-15355 Localization denotes localized
T7971 15397-15412 Positive_regulation denotes Co-transfection
T7970 15397-15412 Positive_regulation denotes Co-transfection
T7969 15397-15412 Gene_expression denotes Co-transfection
T7968 15397-15412 Gene_expression denotes Co-transfection
T7962 15416-15419 Protein denotes p53
T7963 15424-15428 Protein denotes p53β
T7975 15429-15438 Positive_regulation denotes increases
T7974 15429-15438 Positive_regulation denotes increases
T7973 15429-15438 Positive_regulation denotes increases
T7972 15429-15438 Positive_regulation denotes increases
T7964 15439-15442 Protein denotes p53
T7977 15471-15484 Gene_expression denotes co-expression
T7976 15471-15484 Gene_expression denotes co-expression
T7965 15488-15491 Protein denotes p53
T7966 15497-15504 Protein denotes Δ133p53
T7967 15516-15519 Protein denotes p53
T7978 15563-15570 Protein denotes Δ133p53
T7979 15615-15618 Protein denotes p53
T7986 15678-15691 Gene_expression denotes Co-expression
T7985 15678-15691 Gene_expression denotes Co-expression
T7980 15695-15703 Protein denotes Δ133p53β
T7981 15721-15724 Protein denotes p53
T7988 15734-15740 Regulation denotes affect
T7987 15734-15740 Regulation denotes affect
T7982 15741-15744 Protein denotes p53
T7983 15773-15776 Protein denotes p21
T7984 15781-15794 Protein denotes Bax promoters
T9061 15852-15863 Protein denotes p53 mutants
T9064 16064-16068 Negative_regulation denotes Loss
T9062 16083-16086 Protein denotes p53
T9063 16139-16152 Protein denotes wild type p53
T9065 16205-16216 Protein denotes p53 mutants
T9070 16274-16281 Regulation denotes Altered
T9066 16282-16286 Protein denotes WWOX
T9068 16287-16297 Gene_expression denotes expression
T9069 16325-16339 Negative_regulation denotes downregulation
T9067 16343-16347 Protein denotes WWOX
T9071 16552-16555 Protein denotes p53
T9072 16640-16644 Protein denotes WWOX
T9074 16671-16681 Gene_expression denotes expressing
T9073 16692-16695 Protein denotes p53
T9075 16784-16793 Protein denotes caspase-3
T9076 17013-17024 Protein denotes p53 mutants
T9077 17029-17033 Protein denotes WWOX
T9080 17035-17044 Positive_regulation denotes Activated
T9078 17045-17049 Protein denotes WWOX
T9081 17050-17055 Binding denotes binds
T9079 17066-17069 Protein denotes p53
T9082 17081-17096 Phosphorylation denotes phosphorylation
T9084 17211-17218 Binding denotes binding
T9083 17240-17244 Protein denotes WWOX
T9085 17308-17321 Protein denotes wild type p53
T9086 17334-17347 Protein denotes WWOX proteins
T9087 17463-17482 Protein denotes Mutant p53 proteins
T9089 17490-17494 Binding denotes bind
T9088 17526-17530 Protein denotes WWOX
T9091 17597-17607 Gene_expression denotes expressing
T9090 17608-17620 Protein denotes p53 isoforms
T11333 17741-17748 Binding denotes Binding
T11332 17741-17748 Binding denotes Binding
T11331 17741-17748 Binding denotes Binding
T11329 17762-17766 Protein denotes WWOX
T11330 17774-17777 Protein denotes p53
T11334 17843-17847 Protein denotes WWOX
T11339 17848-17853 Binding denotes binds
T11338 17848-17853 Binding denotes binds
T11337 17848-17853 Binding denotes binds
T11335 17854-17857 Protein denotes MEK
T11336 17940-17943 Protein denotes Lin
T11340 18010-18014 Protein denotes WWOX
T11341 18015-18018 Protein denotes MEK
T11343 18251-18261 Negative_regulation denotes inhibition
T11342 18265-18268 Protein denotes MEK
T11344 18440-18443 Protein denotes C1q
T11345 18631-18635 Protein denotes WWOX
T11346 18639-18648 Positive_regulation denotes activated
T11347 18692-18696 Protein denotes WWOX
T11348 18756-18759 Protein denotes p53
T11349 18828-18831 Protein denotes p53
T11351 18845-18854 Binding denotes interacts
T11350 18860-18864 Protein denotes WWOX
T11352 19023-19043 Protein denotes p53-binding proteins
T11353 19117-19121 Protein denotes WWOX
T11354 19126-19129 Protein denotes p53
T11355 19303-19306 Protein denotes p53
T11356 19308-19312 Protein denotes WWOX
T11357 19314-19319 Protein denotes Smad4
T11358 19321-19325 Protein denotes PTEN
T11359 19327-19331 Protein denotes PP2A
T11364 19361-19372 Positive_regulation denotes upregulated
T11363 19361-19372 Positive_regulation denotes upregulated
T11362 19361-19372 Positive_regulation denotes upregulated
T11361 19361-19372 Positive_regulation denotes upregulated
T11360 19361-19372 Positive_regulation denotes upregulated
T11366 19662-19673 Binding denotes counteracts
T11365 19683-19709 Protein denotes function of endogenous p53
T11367 19892-19896 Protein denotes PI3K
T11368 19898-19901 Protein denotes Akt
T11369 19903-19907 Protein denotes mTOR
T11370 19909-19914 Protein denotes NF-κB
T11376 20042-20049 Gene_expression denotes possess
T11375 20042-20049 Gene_expression denotes possess
T11374 20042-20049 Gene_expression denotes possess
T11371 20050-20054 Protein denotes CD44
T11378 20073-20084 Binding denotes interacting
T11377 20073-20084 Binding denotes interacting
T11372 20162-20184 Protein denotes secrete hyaluronidases
T11373 20189-20207 Protein denotes metalloproteinases
T11381 20312-20316 Negative_regulation denotes lack
T11379 20320-20324 Protein denotes WWOX
T11380 20325-20335 Gene_expression denotes expression
T11388 20519-20529 Gene_expression denotes expression
T11387 20519-20529 Gene_expression denotes expression
T11386 20519-20529 Gene_expression denotes expression
T11382 20533-20538 Protein denotes TIAF1
T11383 20540-20545 Protein denotes TGF-β
T11384 20577-20580 Protein denotes p53
T11385 20586-20590 Protein denotes WWOX
T11389 21067-21071 Protein denotes WWOX
T11390 21224-21228 Protein denotes WWOX
T11391 21229-21237 Gene_expression denotes negative
T11392 21367-21371 Protein denotes WWOX
T11393 21372-21382 Gene_expression denotes expressing
T11394 21988-21997 Protein denotes Wwox gene
T11396 21998-22008 Gene_expression denotes expression
T11395 22017-22020 Protein denotes ROS
T11397 22021-22031 Gene_expression denotes production
T11398 22181-22185 Protein denotes WWOX
T11399 22416-22419 Protein denotes p53
T11400 22424-22428 Protein denotes WWOX
T11401 22499-22503 Protein denotes WWOX
T11402 22590-22594 Protein denotes WWOX
T11403 22595-22605 Negative_regulation denotes deficiency
T12531 22773-22776 Protein denotes p53
T12532 22781-22785 Protein denotes WWOX
T12533 22811-22814 Protein denotes Jen
R1526 T2273 T2274 themeOf antiapoptotic Bcl-2,inhibition
R1529 T2278 T2279 themeOf Rad3-related protein kinase,activation
R1530 T2280 T2281 themeOf MGMT,expression
R1532 T2281 T2282 themeOf expression,loss
R1533 T2284 T2286 themeOf MGMT,increase
R1534 T2285 T2287 themeOf MGMT protein,expression
R1537 T2287 T2288 themeOf expression,blocks
R1538 T2289 T2292 themeOf Bax,reduces
R1540 T2290 T2293 themeOf Bcl-2,reduces
R1541 T2291 T2294 themeOf caspase-3,reduces
R1544 T2300 T2301 themeOf cytochrome c oxidase,regulated
R1546 T2307 T2309 themeOf STAT3,inhibitor
R1547 T2308 T2310 themeOf STAT3,knockdown
R1548 T2310 T2311 themeOf knockdown,inhibitor
R1549 T2312 T2313 themeOf CD133,positive
R239 T480 T481 themeOf WWOX gene,expression
R240 T481 T482 themeOf expression,Loss
R241 T482 T483 themeOf Loss,blockade
R242 T484 T485 themeOf type WWOX,expression
R243 T486 T488 themeOf WWOX,bind
R244 T486 T489 themeOf WWOX,bind
R245 T487 T489 themeOf p53,bind
R246 T492 T494 causeOf p53,modulate
R247 T493 T494 themeOf WWOX,modulate
R248 T495 T496 themeOf p53,deficiency
R3757 T5422 T5423 themeOf SDR domain,interacting
R3767 T5424 T5425 themeOf WWOX gene,Restoration
R3768 T5425 T5426 themeOf Restoration,prevents
R3770 T5428 T5436 themeOf WWOX,interact
R3771 T5435 T5436 themeOf RUNX4,interact
R3772 T5437 T5441 themeOf WWOX,overexpressed
R3773 T5437 T5443 themeOf WWOX,binds
R3774 T5437 T5444 themeOf WWOX,binds
R3775 T5437 T5445 themeOf WWOX,binds
R3776 T5439 T5444 themeOf p73,binds
R3777 T5440 T5445 themeOf c-Jun,binds
R3778 T5441 T5442 themeOf overexpressed,overexpressed
R3780 T5446 T5447 themeOf WWOX,binds
R3782 T5448 T5450 themeOf Activated WWOX,interacts
R3783 T5449 T5451 themeOf p53,stabilizes
R3785 T5452 T5455 themeOf WWOX,binds
R3787 T5461 T5464 themeOf inhibitor Bcl-2,down-regulating
R3788 T5462 T5465 themeOf Bcl-xL,down-regulating
R3789 T5463 T5466 themeOf p53,up-regulating
R3792 T5469 T5471 themeOf MEK,binds
R3793 T5469 T5472 themeOf MEK,binds
R3794 T5470 T5472 themeOf Lin,binds
R3797 T5475 T5477 themeOf WWOX,induces
R3800 T5478 T5479 themeOf MEK,Inhibition
R3801 T5480 T5484 themeOf WWOX,expression
R3802 T5481 T5485 themeOf procaspase-3,activation
R3803 T5482 T5486 themeOf procaspase,activation
R3804 T5483 T5487 themeOf cytochrome C,releasing
R3807 T5488 T5491 causeOf Complement C1q,induces
R3808 T5489 T5490 themeOf WWOX,phosphorylation
R3810 T5490 T5491 themeOf phosphorylation,induces
R3811 T5492 T5497 themeOf WWOX,binding
R3812 T5492 T5500 themeOf WWOX,binding
R3813 T5492 T5501 themeOf WWOX,binding
R3814 T5492 T5502 themeOf WWOX,binding
R3815 T5492 T5503 themeOf WWOX,binding
R3816 T5492 T5504 themeOf WWOX,binding
R3817 T5493 T5498 themeOf hyaluronidase,binding
R3818 T5493 T5500 themeOf hyaluronidase,binding
R3819 T5493 T5504 themeOf hyaluronidase,binding
R3820 T5494 T5501 themeOf Phospho,binding
R3821 T5495 T5502 themeOf Ezrin,binding
R3822 T5496 T5499 themeOf Jin,binding
R3823 T5496 T5503 themeOf Jin,binding
R3824 T5496 T5504 themeOf Jin,binding
R3826 T5505 T5510 themeOf Transforming growth factor β1,binds
R3829 T5509 T5511 themeOf SMAD-driven promoter,enhancing
R4987 T7127 T7128 themeOf p53,Activated
R4988 T7135 T7136 themeOf antiapoptotic gene BCL-2,inhibiting
R4989 T7138 T7151 causeOf p53,controlling
R4990 T7138 T7152 causeOf p53,controlling
R4991 T7138 T7153 causeOf p53,controlling
R4992 T7138 T7154 causeOf p53,controlling
R4993 T7139 T7143 themeOf smooth muscle α-actin,expression
R4994 T7140 T7144 themeOf collagens IIα1,expression
R4995 T7141 T7145 themeOf VIα1,expression
R4996 T7142 T7146 themeOf Sun,expression
R4997 T7143 T7147 themeOf expression,regulating
R4998 T7144 T7148 themeOf expression,regulating
R4999 T7145 T7149 themeOf expression,regulating
R5000 T7146 T7150 themeOf expression,regulating
R5001 T7147 T7151 themeOf regulating,controlling
R5002 T7148 T7152 themeOf regulating,controlling
R5003 T7149 T7153 themeOf regulating,controlling
R5004 T7150 T7154 themeOf regulating,controlling
R5495 T7945 T7946 themeOf p53 isoforms,expression
R5496 T7947 T7950 themeOf "Full-length p53, Δ133p53",localized
R5497 T7948 T7951 themeOf p53β,localized
R5498 T7949 T7950 locationOf nucleus,localized
R5499 T7949 T7951 locationOf nucleus,localized
R5500 T7952 T7956 themeOf p53γ,localized
R5501 T7952 T7958 themeOf p53γ,localized
R5502 T7953 T7957 themeOf Δ133p53β,localized
R5503 T7953 T7959 themeOf Δ133p53β,localized
R5504 T7954 T7956 locationOf nucleus,localized
R5505 T7954 T7957 locationOf nucleus,localized
R5506 T7955 T7958 locationOf cytoplasm,localized
R5507 T7955 T7959 locationOf cytoplasm,localized
R5508 T7960 T7961 themeOf Δ133p53γ,localized
R5509 T7962 T7968 themeOf p53,Co-transfection
R5510 T7963 T7969 themeOf p53β,Co-transfection
R5511 T7965 T7976 themeOf p53,co-expression
R5512 T7966 T7977 themeOf Δ133p53,co-expression
R5513 T7968 T7970 themeOf Co-transfection,Co-transfection
R5514 T7968 T7972 themeOf Co-transfection,increases
R5515 T7968 T7974 themeOf Co-transfection,increases
R5516 T7969 T7971 themeOf Co-transfection,Co-transfection
R5517 T7969 T7973 themeOf Co-transfection,increases
R5518 T7969 T7975 themeOf Co-transfection,increases
R5519 T7970 T7972 causeOf Co-transfection,increases
R5520 T7970 T7973 causeOf Co-transfection,increases
R5521 T7971 T7974 causeOf Co-transfection,increases
R5522 T7971 T7975 causeOf Co-transfection,increases
R5523 T7980 T7985 themeOf Δ133p53β,Co-expression
R5524 T7981 T7986 themeOf p53,Co-expression
R5525 T7985 T7987 themeOf Co-expression,affect
R5526 T7986 T7988 themeOf Co-expression,affect
R6206 T9062 T9064 themeOf p53,Loss
R6207 T9066 T9068 themeOf WWOX,expression
R6208 T9067 T9069 themeOf WWOX,downregulation
R6209 T9068 T9070 themeOf expression,Altered
R6210 T9073 T9074 themeOf p53,expressing
R6211 T9078 T9080 themeOf WWOX,Activated
R6212 T9078 T9081 themeOf WWOX,binds
R6213 T9079 T9082 themeOf p53,phosphorylation
R6214 T9083 T9084 themeOf WWOX,binding
R6215 T9087 T9089 themeOf Mutant p53 proteins,bind
R6216 T9090 T9091 themeOf p53 isoforms,expressing
R7713 T11329 T11331 themeOf WWOX,Binding
R7714 T11329 T11333 themeOf WWOX,Binding
R7715 T11330 T11332 themeOf p53,Binding
R7716 T11330 T11333 themeOf p53,Binding
R7717 T11334 T11337 themeOf WWOX,binds
R7718 T11334 T11339 themeOf WWOX,binds
R7719 T11335 T11338 themeOf MEK,binds
R7720 T11335 T11339 themeOf MEK,binds
R7721 T11342 T11343 themeOf MEK,inhibition
R7722 T11345 T11346 themeOf WWOX,activated
R7723 T11349 T11351 themeOf p53,interacts
R7724 T11350 T11351 themeOf WWOX,interacts
R7725 T11355 T11360 themeOf p53,upregulated
R7726 T11356 T11361 themeOf WWOX,upregulated
R7727 T11357 T11362 themeOf Smad4,upregulated
R7728 T11358 T11363 themeOf PTEN,upregulated
R7729 T11359 T11364 themeOf PP2A,upregulated
R7730 T11365 T11366 themeOf function of endogenous p53,counteracts
R7731 T11371 T11374 themeOf CD44,possess
R7732 T11371 T11377 themeOf CD44,interacting
R7733 T11371 T11378 themeOf CD44,interacting
R7734 T11372 T11375 themeOf secrete hyaluronidases,possess
R7735 T11372 T11377 themeOf secrete hyaluronidases,interacting
R7736 T11373 T11376 themeOf metalloproteinases,possess
R7737 T11373 T11378 themeOf metalloproteinases,interacting
R7738 T11379 T11380 themeOf WWOX,expression
R7739 T11380 T11381 themeOf expression,lack
R7740 T11382 T11386 themeOf TIAF1,expression
R7741 T11384 T11387 themeOf p53,expression
R7742 T11385 T11388 themeOf WWOX,expression
R7743 T11390 T11391 themeOf WWOX,negative
R7744 T11392 T11393 themeOf WWOX,expressing
R7745 T11394 T11396 themeOf Wwox gene,expression
R7746 T11395 T11397 themeOf ROS,production
R7747 T11402 T11403 themeOf WWOX,deficiency
R9353 T13503 T13506 themeOf WWOX,phosphorylated
R9354 T13503 T13508 themeOf WWOX,binds
R9355 T13504 T13507 themeOf Tyr33,phosphorylated
R9356 T13505 T13508 themeOf p53,binds
R9357 T13511 T13514 themeOf RUNX2,binds
R9358 T13511 T13517 themeOf RUNX2,binding
R9359 T13512 T13515 themeOf c-Jun,binds
R9360 T13512 T13518 themeOf c-Jun,binding
R9361 T13513 T13516 themeOf ERBB4,binds
R9362 T13513 T13519 themeOf ERBB4,binding
R9363 T13517 T13520 themeOf binding,blocks
R9364 T13518 T13521 themeOf binding,blocks
R9365 T13519 T13522 themeOf binding,blocks
R9366 T13523 T13526 themeOf Tau,binds
R9367 T13524 T13526 themeOf SDR,binds
R9368 T13524 T13525 partOf SDR,domain
R9369 T13525 T13526 Site domain,binds
R9370 T13527 T13531 themeOf WWOX,binding
R9371 T13530 T13531 themeOf Dvl,binding
R9372 T13535 T13538 themeOf WWOX,recruited
R9373 T13536 T13539 themeOf Hyal-2,association
R9374 T13537 T13540 themeOf phospho-Ezrin,association
R9375 T13542 T13545 themeOf TGF-β1,binds
R9376 T13543 T13545 themeOf WWOX,binds
R9377 T13543 T13546 themeOf WWOX,complex
R9378 T13544 T13547 themeOf SMAD-driven promoter,enhancing
R9945 T14512 T14513 themeOf endogenous wild type p53,expressing
R9946 T14514 T14516 themeOf WWOX,binds
R9947 T14517 T14519 themeOf mutant p53 proteins,interactions
R9948 T14518 T14519 themeOf WWOX,interactions
R9949 T14520 T14521 themeOf p53,expressing
R9950 T14523 T14524 themeOf p53 isoforms,expressing