| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T287 |
15-34 |
Protein |
denotes |
Nrf2 Enhances NF-κB |
| T288 |
154-158 |
Protein |
denotes |
Nrf2 |
| T293 |
169-177 |
Positive_regulation |
denotes |
enhances |
| T292 |
207-217 |
Positive_regulation |
denotes |
activation |
| T289 |
221-226 |
Protein |
denotes |
NF-κB |
| T290 |
302-306 |
Protein |
denotes |
Nrf2 |
| T291 |
311-316 |
Protein |
denotes |
NF-κB |
| T294 |
397-410 |
Protein |
denotes |
Nrf2 wildtype |
| T298 |
441-450 |
Regulation |
denotes |
influence |
| T295 |
454-458 |
Protein |
denotes |
Nrf2 |
| T297 |
466-476 |
Positive_regulation |
denotes |
activation |
| T296 |
480-485 |
Protein |
denotes |
NF-κB |
| T299 |
674-679 |
Protein |
denotes |
NF-κB |
| T300 |
734-739 |
Protein |
denotes |
TNF-α |
| T301 |
741-746 |
Protein |
denotes |
IL-1β |
| T302 |
748-752 |
Protein |
denotes |
IL-6 |
| T303 |
758-762 |
Protein |
denotes |
MMP9 |
| T304 |
843-847 |
Protein |
denotes |
MMP9 |
| T305 |
865-870 |
Protein |
denotes |
NF-κB |
| T306 |
936-947 |
Positive_regulation |
denotes |
upregulated |
| T308 |
975-985 |
Gene_expression |
denotes |
expression |
| T307 |
1002-1006 |
Protein |
denotes |
MMP9 |
| T309 |
1017-1025 |
Positive_regulation |
denotes |
elevated |
| T310 |
1072-1079 |
Protein |
denotes |
Nrf2 KO |
| T311 |
1161-1165 |
Protein |
denotes |
Nrf2 |
| T314 |
1170-1176 |
Positive_regulation |
denotes |
induce |
| T313 |
1214-1224 |
Positive_regulation |
denotes |
activation |
| T312 |
1228-1233 |
Protein |
denotes |
NF-κB |
| T908 |
1894-1936 |
Protein |
denotes |
Nuclear factor erythroid 2-related factor2 |
| T907 |
1938-1942 |
Protein |
denotes |
Nrf2 |
| T910 |
1975-1984 |
Regulation |
denotes |
regulates |
| T909 |
1975-1984 |
Regulation |
denotes |
regulates |
| T911 |
2057-2061 |
Protein |
denotes |
Nrf2 |
| T912 |
2205-2209 |
Protein |
denotes |
Nrf2 |
| T914 |
2312-2321 |
Positive_regulation |
denotes |
elevating |
| T913 |
2335-2339 |
Protein |
denotes |
Nrf2 |
| T915 |
2634-2638 |
Protein |
denotes |
Nrf2 |
| T916 |
2726-2730 |
Protein |
denotes |
Nrf2 |
| T1504 |
2939-2943 |
Protein |
denotes |
Nrf2 |
| T1505 |
3114-3118 |
Protein |
denotes |
Nrf2 |
| T1506 |
4184-4188 |
Protein |
denotes |
GFAP |
| T2169 |
5183-5191 |
Protein |
denotes |
μL CCK-8 |
| T2170 |
5319-5322 |
Protein |
denotes |
Rad |
| T2671 |
6286-6306 |
Protein |
denotes |
bovine serum albumin |
| T2672 |
7195-7200 |
Protein |
denotes |
NF-κB |
| T2673 |
7205-7212 |
Binding |
denotes |
binding |
| T3229 |
7555-7577 |
Protein |
denotes |
GoTaq Green Master Mix |
| T3230 |
7788-7802 |
Protein |
denotes |
ImageJ program |
| T3231 |
7817-7824 |
Protein |
denotes |
β-actin |
| T3692 |
8646-8651 |
Protein |
denotes |
actin |
| T3693 |
8711-8741 |
Protein |
denotes |
anti-matrix metallopeptidase 9 |
| T3694 |
8743-8747 |
Protein |
denotes |
MMP9 |
| T3695 |
9004-9026 |
Protein |
denotes |
horseradish peroxidase |
| T3696 |
9328-9335 |
Protein |
denotes |
β-actin |
| T4311 |
9596-9602 |
Gene_expression |
denotes |
Levels |
| T4310 |
9596-9602 |
Gene_expression |
denotes |
Levels |
| T4309 |
9596-9602 |
Gene_expression |
denotes |
Levels |
| T4308 |
9596-9602 |
Gene_expression |
denotes |
Levels |
| T4307 |
9596-9602 |
Gene_expression |
denotes |
Levels |
| T4306 |
9596-9602 |
Gene_expression |
denotes |
Levels |
| T4300 |
9606-9633 |
Protein |
denotes |
tumor necrosis factor-alpha |
| T4301 |
9635-9640 |
Protein |
denotes |
TNF-α |
| T4302 |
9643-9661 |
Protein |
denotes |
interleukin-1 beta |
| T4303 |
9663-9668 |
Protein |
denotes |
IL-1β |
| T4304 |
9675-9688 |
Protein |
denotes |
interleukin-6 |
| T4305 |
9690-9694 |
Protein |
denotes |
IL-6 |
| T4312 |
10102-10114 |
Protein |
denotes |
streptavidin |
| T4313 |
10115-10118 |
Protein |
denotes |
HRP |
| T4314 |
10395-10398 |
Protein |
denotes |
Rad |
| T4559 |
11111-11115 |
Protein |
denotes |
MMP9 |
| T5064 |
11677-11686 |
Negative_regulation |
denotes |
Depletion |
| T5063 |
11690-11694 |
Protein |
denotes |
Nrf2 |
| T5215 |
12251-12255 |
Protein |
denotes |
Nrf2 |
| T5218 |
12256-12264 |
Positive_regulation |
denotes |
Enhanced |
| T5217 |
12265-12277 |
Positive_regulation |
denotes |
Upregulation |
| T5216 |
12281-12286 |
Protein |
denotes |
NF-κB |
| T5219 |
12355-12360 |
Protein |
denotes |
NF-κB |
| T5220 |
12364-12373 |
Positive_regulation |
denotes |
activated |
| T5221 |
12443-12448 |
Protein |
denotes |
NF-κB |
| T5222 |
12468-12475 |
Protein |
denotes |
Nrf2 WT |
| T5226 |
12540-12547 |
Positive_regulation |
denotes |
induced |
| T5225 |
12548-12558 |
Positive_regulation |
denotes |
activation |
| T5223 |
12562-12567 |
Protein |
denotes |
NF-κB |
| T5224 |
12614-12619 |
Protein |
denotes |
NF-κB |
| T5900 |
12786-12794 |
Positive_regulation |
denotes |
Elevated |
| T5899 |
12798-12802 |
Protein |
denotes |
Nrf2 |
| T5901 |
12860-12865 |
Protein |
denotes |
TNF-α |
| T5902 |
12867-12872 |
Protein |
denotes |
IL-1β |
| T5903 |
12878-12882 |
Protein |
denotes |
IL-6 |
| T5908 |
12887-12896 |
Regulation |
denotes |
regulated |
| T5907 |
12887-12896 |
Regulation |
denotes |
regulated |
| T5906 |
12887-12896 |
Regulation |
denotes |
regulated |
| T5904 |
12900-12905 |
Protein |
denotes |
NF-κB |
| T5905 |
12945-12950 |
Protein |
denotes |
NF-κB |
| T5909 |
13170-13174 |
Protein |
denotes |
Nrf2 |
| T5910 |
13175-13184 |
Negative_regulation |
denotes |
deficient |
| T5911 |
13282-13286 |
Protein |
denotes |
Nrf2 |
| T5912 |
13342-13347 |
Protein |
denotes |
TNF-α |
| T5913 |
13349-13354 |
Protein |
denotes |
IL-1β |
| T5914 |
13360-13364 |
Protein |
denotes |
IL-6 |
| T5920 |
13465-13471 |
Transcription |
denotes |
levels |
| T5919 |
13465-13471 |
Transcription |
denotes |
levels |
| T5918 |
13465-13471 |
Transcription |
denotes |
levels |
| T5915 |
13475-13480 |
Protein |
denotes |
TNF-α |
| T5916 |
13482-13487 |
Protein |
denotes |
IL-1β |
| T5917 |
13493-13497 |
Protein |
denotes |
IL-6 |
| T5923 |
13503-13512 |
Positive_regulation |
denotes |
increased |
| T5922 |
13503-13512 |
Positive_regulation |
denotes |
increased |
| T5921 |
13503-13512 |
Positive_regulation |
denotes |
increased |
| T5924 |
13757-13762 |
Protein |
denotes |
TNF-α |
| T5925 |
13801-13806 |
Protein |
denotes |
IL-1β |
| T5926 |
13942-13947 |
Protein |
denotes |
TNF-α |
| T5927 |
13952-13963 |
Positive_regulation |
denotes |
upregulated |
| T5928 |
14223-14227 |
Protein |
denotes |
IL-6 |
| T5929 |
14232-14237 |
Protein |
denotes |
IL-1β |
| T5930 |
14243-14247 |
Protein |
denotes |
IL-6 |
| T5931 |
14354-14359 |
Protein |
denotes |
IL-1β |
| T6748 |
14470-14480 |
Gene_expression |
denotes |
Expression |
| T6746 |
14497-14501 |
Protein |
denotes |
MMP9 |
| T6749 |
14515-14523 |
Positive_regulation |
denotes |
Enhanced |
| T6747 |
14527-14531 |
Protein |
denotes |
Nrf2 |
| T6750 |
14573-14577 |
Protein |
denotes |
MMP9 |
| T6752 |
14679-14687 |
Positive_regulation |
denotes |
elevated |
| T6751 |
14730-14734 |
Protein |
denotes |
MMP9 |
| T6754 |
14828-14838 |
Gene_expression |
denotes |
Expression |
| T6753 |
14842-14846 |
Protein |
denotes |
MMP9 |
| T6755 |
14851-14859 |
Positive_regulation |
denotes |
elevated |
| T6756 |
14965-14969 |
Protein |
denotes |
MMP9 |
| T6757 |
15134-15138 |
Protein |
denotes |
MMP9 |
| T6758 |
15296-15300 |
Protein |
denotes |
MMP9 |
| T8561 |
15482-15489 |
Positive_regulation |
denotes |
induced |
| T8560 |
15482-15489 |
Positive_regulation |
denotes |
induced |
| T8559 |
15482-15489 |
Positive_regulation |
denotes |
induced |
| T8558 |
15482-15489 |
Positive_regulation |
denotes |
induced |
| T8553 |
15482-15489 |
Positive_regulation |
denotes |
induced |
| T8552 |
15482-15489 |
Positive_regulation |
denotes |
induced |
| T8551 |
15482-15489 |
Positive_regulation |
denotes |
induced |
| T8550 |
15482-15489 |
Positive_regulation |
denotes |
induced |
| T8549 |
15482-15489 |
Positive_regulation |
denotes |
induced |
| T8548 |
15482-15489 |
Positive_regulation |
denotes |
induced |
| T8547 |
15482-15489 |
Positive_regulation |
denotes |
induced |
| T8546 |
15482-15489 |
Positive_regulation |
denotes |
induced |
| T8557 |
15494-15506 |
Positive_regulation |
denotes |
upregulation |
| T8556 |
15494-15506 |
Positive_regulation |
denotes |
upregulation |
| T8555 |
15494-15506 |
Positive_regulation |
denotes |
upregulation |
| T8554 |
15494-15506 |
Positive_regulation |
denotes |
upregulation |
| T8533 |
15510-15515 |
Protein |
denotes |
NF-κB |
| T8545 |
15541-15555 |
Positive_regulation |
denotes |
overexpression |
| T8544 |
15541-15555 |
Positive_regulation |
denotes |
overexpression |
| T8543 |
15541-15555 |
Positive_regulation |
denotes |
overexpression |
| T8542 |
15541-15555 |
Positive_regulation |
denotes |
overexpression |
| T8541 |
15541-15555 |
Gene_expression |
denotes |
overexpression |
| T8540 |
15541-15555 |
Gene_expression |
denotes |
overexpression |
| T8539 |
15541-15555 |
Gene_expression |
denotes |
overexpression |
| T8538 |
15541-15555 |
Gene_expression |
denotes |
overexpression |
| T8534 |
15559-15564 |
Protein |
denotes |
TNF-α |
| T8535 |
15566-15571 |
Protein |
denotes |
IL-1β |
| T8536 |
15573-15577 |
Protein |
denotes |
IL-6 |
| T8537 |
15583-15587 |
Protein |
denotes |
MMP9 |
| T8565 |
15649-15656 |
Positive_regulation |
denotes |
induced |
| T8562 |
15676-15681 |
Protein |
denotes |
NF-κB |
| T8564 |
15695-15705 |
Gene_expression |
denotes |
expression |
| T8563 |
15738-15742 |
Protein |
denotes |
Nrf2 |
| T8566 |
15856-15861 |
Protein |
denotes |
NF-κB |
| T8567 |
15865-15874 |
Positive_regulation |
denotes |
activated |
| T8568 |
15955-15960 |
Protein |
denotes |
NF-κB |
| T8574 |
16002-16009 |
Positive_regulation |
denotes |
induces |
| T8573 |
16010-16023 |
Transcription |
denotes |
transcription |
| T8569 |
16027-16031 |
Protein |
denotes |
MMP9 |
| T8570 |
16086-16091 |
Protein |
denotes |
TNF-α |
| T8571 |
16093-16098 |
Protein |
denotes |
IL-1β |
| T8572 |
16104-16108 |
Protein |
denotes |
IL-6 |
| T8582 |
16196-16203 |
Positive_regulation |
denotes |
induced |
| T8581 |
16196-16203 |
Positive_regulation |
denotes |
induced |
| T8580 |
16196-16203 |
Positive_regulation |
denotes |
induced |
| T8583 |
16204-16213 |
Positive_regulation |
denotes |
elevation |
| T8577 |
16204-16213 |
Positive_regulation |
denotes |
elevation |
| T8575 |
16217-16222 |
Protein |
denotes |
NF-κB |
| T8579 |
16245-16259 |
Positive_regulation |
denotes |
overexpression |
| T8578 |
16245-16259 |
Gene_expression |
denotes |
overexpression |
| T8576 |
16263-16267 |
Protein |
denotes |
MMP9 |
| T8584 |
16453-16458 |
Protein |
denotes |
TNF-α |
| T8585 |
16463-16468 |
Protein |
denotes |
IL-1β |
| T8593 |
16480-16491 |
Positive_regulation |
denotes |
stimulators |
| T8592 |
16480-16491 |
Positive_regulation |
denotes |
stimulators |
| T8586 |
16496-16500 |
Protein |
denotes |
MMP9 |
| T8587 |
16529-16533 |
Protein |
denotes |
IL-6 |
| T8596 |
16534-16541 |
Positive_regulation |
denotes |
induces |
| T8594 |
16542-16556 |
Positive_regulation |
denotes |
overexpression |
| T8588 |
16560-16564 |
Protein |
denotes |
MMP9 |
| T8589 |
16606-16611 |
Protein |
denotes |
TNF-α |
| T8590 |
16616-16621 |
Protein |
denotes |
IL-1β |
| T8598 |
16631-16637 |
Positive_regulation |
denotes |
induce |
| T8597 |
16631-16637 |
Positive_regulation |
denotes |
induce |
| T8595 |
16638-16648 |
Positive_regulation |
denotes |
activation |
| T8591 |
16652-16657 |
Protein |
denotes |
NF-κB |
| T8599 |
16892-16896 |
Protein |
denotes |
Nrf2 |
| T8600 |
16897-16900 |
Protein |
denotes |
ARE |
| T8601 |
16939-16948 |
Regulation |
denotes |
regulator |
| T8603 |
17104-17116 |
Positive_regulation |
denotes |
augmentation |
| T8602 |
17120-17124 |
Protein |
denotes |
Nrf2 |
| T8608 |
17157-17165 |
Positive_regulation |
denotes |
Enhanced |
| T8604 |
17175-17179 |
Protein |
denotes |
Nrf2 |
| T8614 |
17180-17189 |
Positive_regulation |
denotes |
activates |
| T8613 |
17180-17189 |
Positive_regulation |
denotes |
activates |
| T8612 |
17180-17189 |
Positive_regulation |
denotes |
activates |
| T8611 |
17190-17203 |
Transcription |
denotes |
transcription |
| T8610 |
17190-17203 |
Transcription |
denotes |
transcription |
| T8609 |
17190-17203 |
Transcription |
denotes |
transcription |
| T8605 |
17245-17261 |
Protein |
denotes |
heme oxygenase-1 |
| T8607 |
17263-17267 |
Protein |
denotes |
HO-1 |
| T8606 |
17309-17313 |
Protein |
denotes |
NQO1 |
| T8615 |
17403-17406 |
Protein |
denotes |
SFN |
| T8618 |
17411-17418 |
Positive_regulation |
denotes |
inducer |
| T8617 |
17411-17418 |
Positive_regulation |
denotes |
inducer |
| T8616 |
17422-17426 |
Protein |
denotes |
Nrf2 |
| T8621 |
17477-17486 |
Negative_regulation |
denotes |
decreases |
| T8620 |
17477-17486 |
Negative_regulation |
denotes |
decreases |
| T8619 |
17477-17486 |
Negative_regulation |
denotes |
decreases |
| T8622 |
17655-17659 |
Protein |
denotes |
Nrf2 |
| T8623 |
17660-17669 |
Negative_regulation |
denotes |
deficient |
| T8625 |
17707-17716 |
Negative_regulation |
denotes |
Depletion |
| T8624 |
17720-17724 |
Protein |
denotes |
Nrf2 |
| T8635 |
17837-17851 |
Positive_regulation |
denotes |
overexpression |
| T8634 |
17837-17851 |
Positive_regulation |
denotes |
overexpression |
| T8633 |
17837-17851 |
Positive_regulation |
denotes |
overexpression |
| T8632 |
17837-17851 |
Gene_expression |
denotes |
overexpression |
| T8631 |
17837-17851 |
Gene_expression |
denotes |
overexpression |
| T8630 |
17837-17851 |
Gene_expression |
denotes |
overexpression |
| T8626 |
17855-17860 |
Protein |
denotes |
TNF-α |
| T8627 |
17862-17867 |
Protein |
denotes |
IL-1β |
| T8628 |
17869-17873 |
Protein |
denotes |
IL-6 |
| T8629 |
17937-17941 |
Protein |
denotes |
Nrf2 |
| T8636 |
18181-18185 |
Protein |
denotes |
Nrf2 |
| T8637 |
18267-18272 |
Protein |
denotes |
NF-κB |
| T8638 |
18302-18305 |
Protein |
denotes |
SFN |
| T8654 |
18329-18336 |
Negative_regulation |
denotes |
inhibit |
| T8653 |
18329-18336 |
Negative_regulation |
denotes |
inhibit |
| T8652 |
18329-18336 |
Negative_regulation |
denotes |
inhibit |
| T8651 |
18329-18336 |
Negative_regulation |
denotes |
inhibit |
| T8650 |
18329-18336 |
Negative_regulation |
denotes |
inhibit |
| T8639 |
18337-18340 |
Protein |
denotes |
IKK |
| T8640 |
18341-18344 |
Protein |
denotes |
IκB |
| T8645 |
18345-18360 |
Phosphorylation |
denotes |
phosphorylation |
| T8644 |
18345-18360 |
Phosphorylation |
denotes |
phosphorylation |
| T8641 |
18365-18371 |
Protein |
denotes |
p65 NF |
| T8642 |
18372-18374 |
Protein |
denotes |
κB |
| T8646 |
18383-18390 |
Entity |
denotes |
nuclear |
| T8649 |
18391-18404 |
Localization |
denotes |
translocation |
| T8648 |
18391-18404 |
Localization |
denotes |
translocation |
| T8647 |
18391-18404 |
Localization |
denotes |
translocation |
| T8643 |
18431-18436 |
Protein |
denotes |
NF-κB |
| T8655 |
18457-18462 |
Protein |
denotes |
NF-κB |
| T8656 |
18541-18545 |
Protein |
denotes |
Nrf2 |
| T8657 |
18566-18569 |
Protein |
denotes |
SFN |
| T8660 |
18643-18652 |
Negative_regulation |
denotes |
depletion |
| T8658 |
18656-18660 |
Protein |
denotes |
Nrf2 |
| T8662 |
18661-18668 |
Positive_regulation |
denotes |
induces |
| T8661 |
18669-18681 |
Positive_regulation |
denotes |
augmentation |
| T8659 |
18685-18690 |
Protein |
denotes |
NF-κB |
| T8667 |
18891-18899 |
Positive_regulation |
denotes |
Enhanced |
| T8668 |
18900-18910 |
Positive_regulation |
denotes |
activation |
| T8665 |
18900-18910 |
Positive_regulation |
denotes |
activation |
| T8663 |
18914-18919 |
Protein |
denotes |
NF-κB |
| T8664 |
18996-19000 |
Protein |
denotes |
Nrf2 |
| T8666 |
19001-19010 |
Negative_regulation |
denotes |
deficient |
| T8669 |
19083-19088 |
Protein |
denotes |
NF-κB |
| T8671 |
19093-19100 |
Negative_regulation |
denotes |
inhibit |
| T8670 |
19101-19105 |
Protein |
denotes |
Nrf2 |
| T8672 |
19132-19149 |
Protein |
denotes |
NF-κB p65 subunit |
| T8673 |
19164-19168 |
Protein |
denotes |
Nrf2 |
| T8674 |
19169-19172 |
Protein |
denotes |
ARE |
| T8678 |
19221-19232 |
Binding |
denotes |
interaction |
| T8675 |
19242-19256 |
Protein |
denotes |
CH1-KIX domain |
| T8676 |
19260-19263 |
Protein |
denotes |
CBP |
| T8677 |
19273-19280 |
Protein |
denotes |
histone |
| T8679 |
19374-19379 |
Protein |
denotes |
NF-κB |
| T8680 |
19384-19388 |
Protein |
denotes |
Nrf2 |
| T8684 |
19403-19412 |
Regulation |
denotes |
regulated |
| T8683 |
19403-19412 |
Regulation |
denotes |
regulated |
| T8681 |
19429-19461 |
Protein |
denotes |
mitogen-activated protein kinase |
| T8682 |
19463-19468 |
Protein |
denotes |
MAPKs |
| T8685 |
19511-19515 |
Protein |
denotes |
Nrf2 |
| T8686 |
19526-19534 |
Gene_expression |
denotes |
detected |
| T8687 |
19601-19605 |
Protein |
denotes |
Nrf2 |
| T8691 |
19752-19762 |
Positive_regulation |
denotes |
activation |
| T8690 |
19752-19762 |
Positive_regulation |
denotes |
activation |
| T8688 |
19766-19770 |
Protein |
denotes |
Nrf2 |
| T8689 |
19771-19774 |
Protein |
denotes |
ARE |
| T8698 |
19824-19834 |
Gene_expression |
denotes |
expression |
| T8697 |
19824-19834 |
Gene_expression |
denotes |
expression |
| T8696 |
19824-19834 |
Gene_expression |
denotes |
expression |
| T8692 |
19838-19843 |
Protein |
denotes |
TNF-α |
| T8693 |
19845-19850 |
Protein |
denotes |
IL-1β |
| T8694 |
19856-19860 |
Protein |
denotes |
IL-6 |
| T8695 |
19912-19925 |
Protein |
denotes |
oxyhemoglobin |
| T8699 |
20258-20262 |
Protein |
denotes |
Nrf2 |
| T8716 |
20317-20329 |
Positive_regulation |
denotes |
demonstrated |
| T8715 |
20317-20329 |
Positive_regulation |
denotes |
demonstrated |
| T8714 |
20317-20329 |
Positive_regulation |
denotes |
demonstrated |
| T8713 |
20317-20329 |
Positive_regulation |
denotes |
demonstrated |
| T8712 |
20334-20345 |
Positive_regulation |
denotes |
upregulated |
| T8711 |
20334-20345 |
Positive_regulation |
denotes |
upregulated |
| T8710 |
20334-20345 |
Positive_regulation |
denotes |
upregulated |
| T8709 |
20334-20345 |
Positive_regulation |
denotes |
upregulated |
| T8708 |
20346-20356 |
Gene_expression |
denotes |
expression |
| T8707 |
20346-20356 |
Gene_expression |
denotes |
expression |
| T8706 |
20346-20356 |
Gene_expression |
denotes |
expression |
| T8705 |
20346-20356 |
Gene_expression |
denotes |
expression |
| T8700 |
20360-20365 |
Protein |
denotes |
TNF-α |
| T8701 |
20367-20372 |
Protein |
denotes |
IL-1β |
| T8702 |
20374-20378 |
Protein |
denotes |
IL-6 |
| T8703 |
20384-20388 |
Protein |
denotes |
MMP9 |
| T8704 |
20392-20396 |
Protein |
denotes |
Nrf2 |
| T8723 |
20473-20482 |
Negative_regulation |
denotes |
depletion |
| T8717 |
20486-20490 |
Protein |
denotes |
Nrf2 |
| T8737 |
20491-20498 |
Positive_regulation |
denotes |
induced |
| T8736 |
20491-20498 |
Positive_regulation |
denotes |
induced |
| T8735 |
20491-20498 |
Positive_regulation |
denotes |
induced |
| T8734 |
20491-20498 |
Positive_regulation |
denotes |
induced |
| T8733 |
20491-20498 |
Positive_regulation |
denotes |
induced |
| T8741 |
20503-20513 |
Positive_regulation |
denotes |
activation |
| T8740 |
20503-20513 |
Positive_regulation |
denotes |
activation |
| T8739 |
20503-20513 |
Positive_regulation |
denotes |
activation |
| T8738 |
20503-20513 |
Positive_regulation |
denotes |
activation |
| T8724 |
20503-20513 |
Positive_regulation |
denotes |
activation |
| T8718 |
20517-20522 |
Protein |
denotes |
NF-κB |
| T8728 |
20531-20541 |
Gene_expression |
denotes |
expression |
| T8727 |
20531-20541 |
Gene_expression |
denotes |
expression |
| T8726 |
20531-20541 |
Gene_expression |
denotes |
expression |
| T8725 |
20531-20541 |
Gene_expression |
denotes |
expression |
| T8719 |
20545-20550 |
Protein |
denotes |
TNF-α |
| T8720 |
20552-20557 |
Protein |
denotes |
IL-1β |
| T8721 |
20559-20563 |
Protein |
denotes |
IL-6 |
| T8722 |
20569-20573 |
Protein |
denotes |
MMP9 |
| T8732 |
20574-20583 |
Gene_expression |
denotes |
resulting |
| T8731 |
20574-20583 |
Gene_expression |
denotes |
resulting |
| T8730 |
20574-20583 |
Gene_expression |
denotes |
resulting |
| T8729 |
20574-20583 |
Gene_expression |
denotes |
resulting |
| T8742 |
20667-20671 |
Protein |
denotes |
Nrf2 |
| R207 |
T289 |
T292 |
themeOf |
NF-κB,activation |
| R208 |
T292 |
T293 |
themeOf |
activation,enhances |
| R209 |
T296 |
T297 |
themeOf |
NF-κB,activation |
| R210 |
T297 |
T298 |
themeOf |
activation,influence |
| R211 |
T298 |
T295 |
Cause |
influence,Nrf2 |
| R212 |
T305 |
T306 |
themeOf |
NF-κB,upregulated |
| R213 |
T307 |
T308 |
themeOf |
MMP9,expression |
| R214 |
T308 |
T309 |
themeOf |
expression,elevated |
| R215 |
T312 |
T313 |
themeOf |
NF-κB,activation |
| R216 |
T313 |
T314 |
themeOf |
activation,induce |
| R2312 |
T2672 |
T2673 |
themeOf |
NF-κB,binding |
| R3695 |
T4300 |
T4306 |
themeOf |
tumor necrosis factor-alpha,Levels |
| R3696 |
T4301 |
T4307 |
themeOf |
TNF-α,Levels |
| R3697 |
T4302 |
T4308 |
themeOf |
interleukin-1 beta,Levels |
| R3698 |
T4303 |
T4309 |
themeOf |
IL-1β,Levels |
| R3699 |
T4304 |
T4310 |
themeOf |
interleukin-6,Levels |
| R3700 |
T4305 |
T4311 |
themeOf |
IL-6,Levels |
| R4318 |
T5063 |
T5064 |
themeOf |
Nrf2,Depletion |
| R4440 |
T5216 |
T5217 |
themeOf |
NF-κB,Upregulation |
| R4441 |
T5217 |
T5218 |
themeOf |
Upregulation,Enhanced |
| R4442 |
T5219 |
T5220 |
themeOf |
NF-κB,activated |
| R4443 |
T5223 |
T5225 |
themeOf |
NF-κB,activation |
| R4444 |
T5225 |
T5226 |
themeOf |
activation,induced |
| R4947 |
T5899 |
T5900 |
themeOf |
Nrf2,Elevated |
| R4948 |
T5901 |
T5906 |
themeOf |
TNF-α,regulated |
| R4949 |
T5902 |
T5907 |
themeOf |
IL-1β,regulated |
| R4950 |
T5903 |
T5908 |
themeOf |
IL-6,regulated |
| R4951 |
T5906 |
T5904 |
Cause |
regulated,NF-κB |
| R4952 |
T5907 |
T5904 |
Cause |
regulated,NF-κB |
| R4953 |
T5908 |
T5904 |
Cause |
regulated,NF-κB |
| R4954 |
T5909 |
T5910 |
themeOf |
Nrf2,deficient |
| R4955 |
T5915 |
T5918 |
themeOf |
TNF-α,levels |
| R4956 |
T5916 |
T5919 |
themeOf |
IL-1β,levels |
| R4957 |
T5917 |
T5920 |
themeOf |
IL-6,levels |
| R4958 |
T5918 |
T5921 |
themeOf |
levels,increased |
| R4959 |
T5919 |
T5922 |
themeOf |
levels,increased |
| R4960 |
T5920 |
T5923 |
themeOf |
levels,increased |
| R4961 |
T5926 |
T5927 |
themeOf |
TNF-α,upregulated |
| R5591 |
T6746 |
T6748 |
themeOf |
MMP9,Expression |
| R5592 |
T6748 |
T6749 |
themeOf |
Expression,Enhanced |
| R5593 |
T6751 |
T6752 |
themeOf |
MMP9,elevated |
| R5594 |
T6753 |
T6754 |
themeOf |
MMP9,Expression |
| R5595 |
T6754 |
T6755 |
themeOf |
Expression,elevated |
| R6932 |
T8534 |
T8538 |
themeOf |
TNF-α,overexpression |
| R6933 |
T8535 |
T8539 |
themeOf |
IL-1β,overexpression |
| R6934 |
T8536 |
T8540 |
themeOf |
IL-6,overexpression |
| R6935 |
T8537 |
T8541 |
themeOf |
MMP9,overexpression |
| R6936 |
T8538 |
T8542 |
themeOf |
overexpression,overexpression |
| R6937 |
T8538 |
T8546 |
themeOf |
overexpression,induced |
| R6938 |
T8538 |
T8554 |
themeOf |
overexpression,upregulation |
| R6939 |
T8539 |
T8543 |
themeOf |
overexpression,overexpression |
| R6940 |
T8539 |
T8547 |
themeOf |
overexpression,induced |
| R6941 |
T8539 |
T8555 |
themeOf |
overexpression,upregulation |
| R6942 |
T8540 |
T8544 |
themeOf |
overexpression,overexpression |
| R6943 |
T8540 |
T8548 |
themeOf |
overexpression,induced |
| R6944 |
T8540 |
T8556 |
themeOf |
overexpression,upregulation |
| R6945 |
T8541 |
T8545 |
themeOf |
overexpression,overexpression |
| R6946 |
T8541 |
T8549 |
themeOf |
overexpression,induced |
| R6947 |
T8541 |
T8557 |
themeOf |
overexpression,upregulation |
| R6948 |
T8542 |
T8550 |
themeOf |
overexpression,induced |
| R6949 |
T8543 |
T8551 |
themeOf |
overexpression,induced |
| R6950 |
T8544 |
T8552 |
themeOf |
overexpression,induced |
| R6951 |
T8545 |
T8553 |
themeOf |
overexpression,induced |
| R6952 |
T8554 |
T8558 |
themeOf |
upregulation,induced |
| R6953 |
T8555 |
T8559 |
themeOf |
upregulation,induced |
| R6954 |
T8556 |
T8560 |
themeOf |
upregulation,induced |
| R6955 |
T8557 |
T8561 |
themeOf |
upregulation,induced |
| R6956 |
T8562 |
T8564 |
themeOf |
NF-κB,expression |
| R6957 |
T8564 |
T8565 |
themeOf |
expression,induced |
| R6958 |
T8566 |
T8567 |
themeOf |
NF-κB,activated |
| R6959 |
T8569 |
T8573 |
themeOf |
MMP9,transcription |
| R6960 |
T8573 |
T8574 |
themeOf |
transcription,induces |
| R6961 |
T8574 |
T8568 |
Cause |
induces,NF-κB |
| R6962 |
T8575 |
T8577 |
themeOf |
NF-κB,elevation |
| R6963 |
T8576 |
T8578 |
themeOf |
MMP9,overexpression |
| R6964 |
T8577 |
T8580 |
themeOf |
elevation,induced |
| R6965 |
T8578 |
T8579 |
themeOf |
overexpression,overexpression |
| R6966 |
T8578 |
T8581 |
themeOf |
overexpression,induced |
| R6967 |
T8578 |
T8583 |
themeOf |
overexpression,elevation |
| R6968 |
T8579 |
T8582 |
themeOf |
overexpression,induced |
| R6969 |
T8586 |
T8592 |
themeOf |
MMP9,stimulators |
| R6970 |
T8586 |
T8593 |
themeOf |
MMP9,stimulators |
| R6971 |
T8588 |
T8594 |
themeOf |
MMP9,overexpression |
| R6972 |
T8591 |
T8595 |
themeOf |
NF-κB,activation |
| R6973 |
T8592 |
T8584 |
Cause |
stimulators,TNF-α |
| R6974 |
T8593 |
T8585 |
Cause |
stimulators,IL-1β |
| R6975 |
T8594 |
T8596 |
themeOf |
overexpression,induces |
| R6976 |
T8595 |
T8597 |
themeOf |
activation,induce |
| R6977 |
T8595 |
T8598 |
themeOf |
activation,induce |
| R6978 |
T8596 |
T8587 |
Cause |
induces,IL-6 |
| R6979 |
T8597 |
T8589 |
Cause |
induce,TNF-α |
| R6980 |
T8598 |
T8590 |
Cause |
induce,IL-1β |
| R6981 |
T8600 |
T8601 |
themeOf |
ARE,regulator |
| R6982 |
T8602 |
T8603 |
themeOf |
Nrf2,augmentation |
| R6983 |
T8604 |
T8608 |
themeOf |
Nrf2,Enhanced |
| R6984 |
T8605 |
T8609 |
themeOf |
heme oxygenase-1,transcription |
| R6985 |
T8606 |
T8610 |
themeOf |
NQO1,transcription |
| R6986 |
T8607 |
T8611 |
themeOf |
HO-1,transcription |
| R6987 |
T8609 |
T8612 |
themeOf |
transcription,activates |
| R6988 |
T8610 |
T8613 |
themeOf |
transcription,activates |
| R6989 |
T8611 |
T8614 |
themeOf |
transcription,activates |
| R6990 |
T8615 |
T8617 |
themeOf |
SFN,inducer |
| R6991 |
T8615 |
T8619 |
themeOf |
SFN,decreases |
| R6992 |
T8616 |
T8618 |
themeOf |
Nrf2,inducer |
| R6993 |
T8617 |
T8620 |
themeOf |
inducer,decreases |
| R6994 |
T8618 |
T8621 |
themeOf |
inducer,decreases |
| R6995 |
T8622 |
T8623 |
themeOf |
Nrf2,deficient |
| R6996 |
T8624 |
T8625 |
themeOf |
Nrf2,Depletion |
| R6997 |
T8626 |
T8630 |
themeOf |
TNF-α,overexpression |
| R6998 |
T8627 |
T8631 |
themeOf |
IL-1β,overexpression |
| R6999 |
T8628 |
T8632 |
themeOf |
IL-6,overexpression |
| R7000 |
T8630 |
T8633 |
themeOf |
overexpression,overexpression |
| R7001 |
T8631 |
T8634 |
themeOf |
overexpression,overexpression |
| R7002 |
T8632 |
T8635 |
themeOf |
overexpression,overexpression |
| R7003 |
T8639 |
T8644 |
themeOf |
IKK,phosphorylation |
| R7004 |
T8639 |
T8647 |
themeOf |
IKK,translocation |
| R7005 |
T8640 |
T8645 |
themeOf |
IκB,phosphorylation |
| R7006 |
T8641 |
T8648 |
themeOf |
p65 NF,translocation |
| R7007 |
T8642 |
T8649 |
themeOf |
κB,translocation |
| R7008 |
T8644 |
T8650 |
themeOf |
phosphorylation,inhibit |
| R7009 |
T8645 |
T8651 |
themeOf |
phosphorylation,inhibit |
| R7010 |
T8647 |
T8646 |
ToLoc |
translocation,nuclear |
| R7011 |
T8647 |
T8652 |
themeOf |
translocation,inhibit |
| R7012 |
T8648 |
T8646 |
ToLoc |
translocation,nuclear |
| R7013 |
T8648 |
T8653 |
themeOf |
translocation,inhibit |
| R7014 |
T8649 |
T8646 |
ToLoc |
translocation,nuclear |
| R7015 |
T8649 |
T8654 |
themeOf |
translocation,inhibit |
| R7016 |
T8658 |
T8660 |
themeOf |
Nrf2,depletion |
| R7017 |
T8659 |
T8661 |
themeOf |
NF-κB,augmentation |
| R7018 |
T8661 |
T8662 |
themeOf |
augmentation,induces |
| R7019 |
T8662 |
T8660 |
Cause |
induces,depletion |
| R7020 |
T8663 |
T8665 |
themeOf |
NF-κB,activation |
| R7021 |
T8664 |
T8666 |
themeOf |
Nrf2,deficient |
| R7022 |
T8665 |
T8667 |
themeOf |
activation,Enhanced |
| R7023 |
T8667 |
T8668 |
themeOf |
Enhanced,activation |
| R7024 |
T8670 |
T8671 |
themeOf |
Nrf2,inhibit |
| R7025 |
T8671 |
T8669 |
Cause |
inhibit,NF-κB |
| R7026 |
T8676 |
T8678 |
themeOf |
CBP,interaction |
| R7027 |
T8679 |
T8683 |
themeOf |
NF-κB,regulated |
| R7028 |
T8680 |
T8684 |
themeOf |
Nrf2,regulated |
| R7029 |
T8685 |
T8686 |
themeOf |
Nrf2,detected |
| R7030 |
T8688 |
T8690 |
themeOf |
Nrf2,activation |
| R7031 |
T8689 |
T8691 |
themeOf |
ARE,activation |
| R7032 |
T8692 |
T8696 |
themeOf |
TNF-α,expression |
| R7033 |
T8693 |
T8697 |
themeOf |
IL-1β,expression |
| R7034 |
T8694 |
T8698 |
themeOf |
IL-6,expression |
| R7035 |
T8700 |
T8705 |
themeOf |
TNF-α,expression |
| R7036 |
T8701 |
T8706 |
themeOf |
IL-1β,expression |
| R7037 |
T8702 |
T8707 |
themeOf |
IL-6,expression |
| R7038 |
T8703 |
T8708 |
themeOf |
MMP9,expression |
| R7039 |
T8705 |
T8709 |
themeOf |
expression,upregulated |
| R7040 |
T8706 |
T8710 |
themeOf |
expression,upregulated |
| R7041 |
T8707 |
T8711 |
themeOf |
expression,upregulated |
| R7042 |
T8708 |
T8712 |
themeOf |
expression,upregulated |
| R7043 |
T8709 |
T8713 |
themeOf |
upregulated,demonstrated |
| R7044 |
T8710 |
T8714 |
themeOf |
upregulated,demonstrated |
| R7045 |
T8711 |
T8715 |
themeOf |
upregulated,demonstrated |
| R7046 |
T8712 |
T8716 |
themeOf |
upregulated,demonstrated |
| R7047 |
T8717 |
T8723 |
themeOf |
Nrf2,depletion |
| R7048 |
T8718 |
T8724 |
themeOf |
NF-κB,activation |
| R7049 |
T8719 |
T8725 |
themeOf |
TNF-α,expression |
| R7050 |
T8719 |
T8729 |
themeOf |
TNF-α,resulting |
| R7051 |
T8720 |
T8726 |
themeOf |
IL-1β,expression |
| R7052 |
T8720 |
T8730 |
themeOf |
IL-1β,resulting |
| R7053 |
T8721 |
T8727 |
themeOf |
IL-6,expression |
| R7054 |
T8721 |
T8731 |
themeOf |
IL-6,resulting |
| R7055 |
T8722 |
T8728 |
themeOf |
MMP9,expression |
| R7056 |
T8722 |
T8732 |
themeOf |
MMP9,resulting |
| R7057 |
T8724 |
T8733 |
themeOf |
activation,induced |
| R7058 |
T8725 |
T8734 |
themeOf |
expression,induced |
| R7059 |
T8725 |
T8738 |
themeOf |
expression,activation |
| R706 |
T907 |
T909 |
themeOf |
Nrf2,regulates |
| R7060 |
T8726 |
T8735 |
themeOf |
expression,induced |
| R7061 |
T8726 |
T8739 |
themeOf |
expression,activation |
| R7062 |
T8727 |
T8736 |
themeOf |
expression,induced |
| R7063 |
T8727 |
T8740 |
themeOf |
expression,activation |
| R7064 |
T8728 |
T8737 |
themeOf |
expression,induced |
| R7065 |
T8728 |
T8741 |
themeOf |
expression,activation |
| R7066 |
T8733 |
T8723 |
Cause |
induced,depletion |
| R7067 |
T8734 |
T8723 |
Cause |
induced,depletion |
| R7068 |
T8735 |
T8723 |
Cause |
induced,depletion |
| R7069 |
T8736 |
T8723 |
Cause |
induced,depletion |
| R707 |
T908 |
T910 |
themeOf |
Nuclear factor erythroid 2-related factor2,regulates |
| R7070 |
T8737 |
T8723 |
Cause |
induced,depletion |
| R708 |
T913 |
T914 |
themeOf |
Nrf2,elevating |
