PMC:3291650 JSONTXT 30 Projects

Annnotations TAB TSV DIC JSON TextAE-old TextAE

Id Subject Object Predicate Lexical cue
T561 0-3 Protein denotes A20
T562 5-12 Protein denotes Tnfaip3
T563 14-24 Negative_regulation denotes Deficiency
T564 14-24 Negative_regulation denotes Deficiency
T565 463-468 Protein denotes RIG-I
T568 473-480 Positive_regulation denotes induces
T567 485-495 Gene_expression denotes production
T566 539-549 Protein denotes interferon
T572 773-777 Gene_expression denotes role
T571 773-777 Gene_expression denotes role
T569 785-810 Protein denotes ubiquitin-editing protein
T570 811-814 Protein denotes A20
T580 973-981 Positive_regulation denotes enhanced
T579 973-981 Positive_regulation denotes enhanced
T573 982-987 Protein denotes NF-κB
T574 992-996 Protein denotes IRF3
T577 997-1007 Positive_regulation denotes activation
T576 997-1007 Positive_regulation denotes activation
T581 1026-1035 Positive_regulation denotes increased
T578 1036-1046 Gene_expression denotes production
T575 1092-1109 Protein denotes type I interferon
T583 1512-1522 Negative_regulation denotes inhibition
T582 1526-1529 Protein denotes A20
T3884 3071-3100 Protein denotes pattern recognition receptors
T3885 3102-3105 Protein denotes PRR
T3910 3197-3204 Positive_regulation denotes induces
T3909 3197-3204 Positive_regulation denotes induces
T3908 3197-3204 Positive_regulation denotes induces
T3907 3197-3204 Positive_regulation denotes induces
T3906 3197-3204 Positive_regulation denotes induces
T3905 3197-3204 Positive_regulation denotes induces
T3904 3197-3204 Positive_regulation denotes induces
T3903 3209-3219 Gene_expression denotes production
T3902 3209-3219 Gene_expression denotes production
T3901 3209-3219 Gene_expression denotes production
T3900 3209-3219 Gene_expression denotes production
T3899 3209-3219 Gene_expression denotes production
T3898 3209-3219 Gene_expression denotes production
T3897 3209-3219 Gene_expression denotes production
T3886 3260-3263 Protein denotes TNF
T3887 3265-3269 Protein denotes IL-6
T3888 3274-3278 Protein denotes IL-1
T3889 3284-3302 Protein denotes type I interferons
T3890 3304-3316 Protein denotes interferon-α
T3891 3318-3323 Protein denotes IFN-α
T3892 3329-3334 Protein denotes IFN-β
T3893 3439-3444 Protein denotes NF-κB
T3894 3446-3450 Protein denotes AP-1
T3895 3452-3456 Protein denotes IRF3
T3896 3461-3469 Protein denotes IRF7 [1]
T3911 3656-3685 Protein denotes Endosomal Toll-like receptors
T3912 3687-3691 Protein denotes TLRs
T3913 3722-3742 Protein denotes RIG-I-like receptors
T3922 3744-3748 Protein denotes RLRs
T3914 3753-3771 Protein denotes Nod-like receptors
T3921 3773-3777 Protein denotes NLRs
T3915 3825-3829 Protein denotes TLR7
T3916 3831-3835 Protein denotes TLR8
T3917 3837-3841 Protein denotes Nod2
T3918 3867-3871 Protein denotes TLR3
T3919 3873-3878 Protein denotes RIG-I
T3920 3880-3884 Protein denotes MDA5
T3923 3976-3980 Protein denotes TLR9
T3924 3998-4010 Protein denotes PYHIN domain
T3927 4011-4021 Gene_expression denotes containing
T3926 4011-4021 Gene_expression denotes containing
T3925 4054-4059 Protein denotes IFI16
T3928 4128-4138 Protein denotes type I IFN
T3929 4139-4148 Gene_expression denotes producing
T3930 4994-4998 Protein denotes TLR3
T3931 5003-5008 Protein denotes RIG-I
T3932 5213-5218 Protein denotes RIG-I
T3933 5330-5334 Protein denotes TLR3
T3934 5335-5344 Negative_regulation denotes deficient
T3935 5609-5628 Protein denotes DExD/H box helicase
T3941 5724-5731 Binding denotes binding
T3940 5724-5731 Binding denotes binding
T3939 5724-5731 Binding denotes binding
T3936 5737-5749 Protein denotes CARD domains
T3937 5753-5758 Protein denotes RIG-I
T3942 5759-5768 Binding denotes associate
T3938 5778-5789 Protein denotes CARD domain
T3943 6011-6015 Protein denotes MAVS
T3944 6047-6056 Protein denotes ubiquitin
T3945 6122-6127 Protein denotes RIG-I
T3946 6163-6193 Protein denotes K63-specific ubiquitin ligases
T3947 6195-6198 Protein denotes E3s
T3950 6272-6279 Gene_expression denotes promote
T3949 6272-6279 Gene_expression denotes promote
T3948 6280-6285 Protein denotes RIG-I
T3951 6286-6296 Positive_regulation denotes activation
T3952 6330-6347 Protein denotes ubiquitin ligases
T3959 6388-6395 Positive_regulation denotes mediate
T3958 6388-6395 Positive_regulation denotes mediate
T3953 6409-6414 Protein denotes NF-κB
T3954 6419-6423 Protein denotes IRF3
T3957 6424-6434 Positive_regulation denotes activation
T3956 6424-6434 Positive_regulation denotes activation
T3955 6440-6445 Protein denotes RIG-I
T3960 6652-6665 Protein denotes polyubiquitin
T3961 6728-6758 Protein denotes K48-specific ubiquitin ligases
T3962 6822-6827 Protein denotes TRAF3
T3964 6852-6863 Protein_catabolism denotes degradation
T3963 6852-6863 Protein_catabolism denotes degradation
T3965 6943-6976 Protein denotes K48-specific polyubiquitin chains
T3966 6984-6988 Protein denotes IRF3
T3967 6993-7019 Protein denotes IRF7 transcription factors
T3968 7062-7067 Protein denotes RBCK1
T3969 7120-7123 Protein denotes A20
T3970 7130-7139 Protein denotes ubiquitin
T3971 7172-7189 Protein denotes OTU-domain family
T3972 7214-7217 Protein denotes A20
T3973 7275-7277 Protein denotes E3
T3974 7278-7294 Protein denotes ubiquitin ligase
T3975 7444-7447 Protein denotes A20
T3976 7490-7504 Protein denotes TNF receptor I
T3977 7573-7576 Protein denotes A20
T3978 7750-7753 Protein denotes A20
T3979 7884-7887 Protein denotes A20
T3980 8071-8080 Protein denotes A20 locus
T3981 8270-8273 Protein denotes A20
T3982 8463-8466 Protein denotes A20
T3983 8491-8495 Protein denotes TLR3
T3984 8517-8522 Protein denotes NF-κB
T3985 8527-8532 Protein denotes IRF-3
T3986 8581-8584 Protein denotes A20
T3987 8815-8818 Protein denotes A20
T3988 9369-9372 Protein denotes A20
T6980 9447-9455 Negative_regulation denotes inhibits
T6981 9456-9469 Positive_regulation denotes RIG-I-induced
T6977 9470-9475 Protein denotes NF-κB
T6978 9480-9484 Protein denotes IRF3
T6982 9485-9495 Positive_regulation denotes activation
T6979 9485-9495 Positive_regulation denotes activation
T6983 9496-9501 Protein denotes RIG-I
T6994 9512-9519 Positive_regulation denotes induces
T6993 9512-9519 Positive_regulation denotes induces
T6992 9512-9519 Positive_regulation denotes induces
T6990 9524-9534 Positive_regulation denotes activation
T6989 9524-9534 Positive_regulation denotes activation
T6988 9524-9534 Positive_regulation denotes activation
T6984 9538-9543 Protein denotes NF-κB
T6985 9545-9549 Protein denotes IRF3
T6986 9554-9580 Protein denotes IRF7 transcription factors
T6997 9588-9595 Positive_regulation denotes promote
T6996 9588-9595 Positive_regulation denotes promote
T6995 9588-9595 Positive_regulation denotes promote
T6991 9600-9610 Gene_expression denotes expression
T6987 9644-9655 Protein denotes type I IFNs
T7002 9742-9751 Gene_expression denotes expressed
T6998 9752-9755 Protein denotes A20
T7006 9767-9776 Regulation denotes regulates
T7005 9767-9776 Regulation denotes regulates
T6999 9777-9782 Protein denotes NF-κB
T7000 9787-9791 Protein denotes IRF3
T7004 9792-9802 Positive_regulation denotes activation
T7003 9792-9802 Positive_regulation denotes activation
T7001 9808-9813 Protein denotes RIG-I
T7007 9861-9864 Protein denotes A20
T7012 9865-9879 Positive_regulation denotes overexpression
T7011 9865-9879 Gene_expression denotes overexpression
T7008 9906-9911 Protein denotes NF-κB
T7009 9917-9921 Protein denotes IRF3
T7010 9932-9942 Protein denotes luciferase
T7013 9968-9975 Positive_regulation denotes induced
T7016 10200-10208 Negative_regulation denotes inhibits
T7014 10209-10213 Protein denotes IRF7
T7015 10214-10224 Positive_regulation denotes activation
T7017 10233-10237 Protein denotes IRF3
T7018 10239-10243 Protein denotes IRF7
T7022 10261-10270 Gene_expression denotes expressed
T7021 10261-10270 Gene_expression denotes expressed
T7019 10298-10310 Protein denotes IRF7 protein
T7024 10330-10341 Positive_regulation denotes upregulated
T7020 10361-10365 Protein denotes IRF3
T7023 10366-10376 Positive_regulation denotes activation
T7025 10423-10427 Protein denotes IRF7
T7033 10453-10464 Positive_regulation denotes transfected
T7032 10453-10464 Positive_regulation denotes transfected
T7031 10453-10464 Gene_expression denotes transfected
T7030 10453-10464 Gene_expression denotes transfected
T7026 10485-10489 Protein denotes IRF7
T7034 10490-10500 Gene_expression denotes expression
T7027 10556-10559 Protein denotes A20
T7028 10567-10571 Protein denotes IRF7
T7029 10581-10606 Protein denotes IFNα4 luciferase reporter
T7035 10661-10665 Protein denotes IRF7
T7038 10666-10679 Gene_expression denotes co-expression
T7036 10698-10712 Protein denotes IFNα4 promoter
T7039 10713-10723 Positive_regulation denotes activation
T7037 10837-10841 Protein denotes IRF7
T7048 10869-10875 Regulation denotes effect
T7047 10869-10875 Regulation denotes effect
T7040 10879-10884 Protein denotes NF-κB
T7041 10889-10893 Protein denotes IRF3
T7045 10894-10904 Positive_regulation denotes activation
T7044 10894-10904 Positive_regulation denotes activation
T7042 10906-10909 Protein denotes A20
T7049 10915-10924 Negative_regulation denotes prevented
T7043 10939-10943 Protein denotes IRF7
T7046 10944-10954 Positive_regulation denotes activation
T7055 11031-11038 Negative_regulation denotes inhibit
T7054 11031-11038 Negative_regulation denotes inhibit
T7050 11053-11058 Protein denotes NF-κB
T7051 11063-11069 Protein denotes IRF3/7
T7053 11070-11080 Positive_regulation denotes activation
T7052 11070-11080 Positive_regulation denotes activation
T20071 11126-11129 Protein denotes A20
T20078 11130-11138 Negative_regulation denotes inhibits
T20077 11130-11138 Negative_regulation denotes inhibits
T20072 11139-11144 Protein denotes NF-κB
T20073 11149-11153 Protein denotes IRF3
T20076 11154-11164 Positive_regulation denotes activation
T20075 11154-11164 Positive_regulation denotes activation
T20074 11180-11185 Protein denotes RIG-I
T20085 11222-11233 Gene_expression denotes transfected
T20084 11222-11233 Gene_expression denotes transfected
T20079 11239-11244 Protein denotes NF-κB
T20080 11253-11257 Protein denotes IRF3
T20081 11270-11304 Protein denotes IRF7 dependent luciferase reporter
T20087 11346-11356 Gene_expression denotes expressing
T20086 11346-11356 Gene_expression denotes expressing
T20082 11372-11376 Protein denotes IRF7
T20083 11411-11414 Protein denotes A20
T20088 11416-11426 Protein denotes Luciferase
T20089 11706-11710 Protein denotes IκBα
T20091 11711-11726 Phosphorylation denotes phosphorylation
T20092 11731-11742 Protein_catabolism denotes degradation
T20090 11748-11752 Protein denotes IRF3
T20093 11753-11768 Phosphorylation denotes phosphorylation
T20095 11849-11859 Binding denotes recognized
T20094 11867-11885 Protein denotes anti-IκBα antibody
T20099 11947-11954 Entity denotes Nuclear
T20102 11955-11968 Localization denotes translocation
T20101 11955-11968 Localization denotes translocation
T20100 11955-11968 Localization denotes translocation
T20096 11972-11977 Protein denotes NF-κB
T20097 11979-11982 Protein denotes p65
T20098 11988-11992 Protein denotes IRF3
T20103 12108-12111 Protein denotes p65
T20104 12116-12120 Protein denotes IRF3
T20106 12145-12154 Gene_expression denotes expressed
T20105 12145-12154 Gene_expression denotes expressed
T20107 12215-12219 Protein denotes IL-6
T20108 12221-12224 Protein denotes TNF
T20109 12229-12233 Protein denotes IFNβ
T20115 12234-12240 Gene_expression denotes levels
T20114 12234-12240 Gene_expression denotes levels
T20113 12234-12240 Gene_expression denotes levels
T20110 12320-12325 Protein denotes ELISA
T20111 12327-12330 Protein denotes TNF
T20112 12335-12339 Protein denotes IFNβ
T7056 12781-12791 Protein denotes A20 allele
T7059 12898-12908 Gene_expression denotes expressing
T7057 12909-12924 Protein denotes Cre recombinase
T7060 12931-12938 Regulation denotes control
T7058 12946-12965 Protein denotes lysozyme M promoter
T7063 13086-13095 Positive_regulation denotes stimulate
T7061 13100-13114 Protein denotes RIG-I receptor
T7064 13279-13287 Positive_regulation denotes activate
T7062 13288-13293 Protein denotes RIG-I
T7070 13372-13378 Positive_regulation denotes induce
T7069 13372-13378 Positive_regulation denotes induce
T7065 13391-13411 Protein denotes TLR3 dependent NF-κB
T7066 13416-13420 Protein denotes IRF3
T7068 13421-13431 Positive_regulation denotes activation
T7067 13421-13431 Positive_regulation denotes activation
T7073 13509-13516 Positive_regulation denotes induced
T7072 13527-13537 Gene_expression denotes expression
T7071 13541-13544 Protein denotes A20
T7079 13829-13837 Positive_regulation denotes enhanced
T7074 13838-13843 Protein denotes NF-κB
T7080 13844-13854 Positive_regulation denotes activation
T7076 13844-13854 Positive_regulation denotes activation
T7082 13871-13880 Positive_regulation denotes increased
T7081 13871-13880 Positive_regulation denotes increased
T7077 13881-13896 Phosphorylation denotes phosphorylation
T7078 13911-13922 Protein_catabolism denotes degradation
T7075 13926-13930 Protein denotes IκBα
T7085 13957-13964 Entity denotes nuclear
T7087 13965-13978 Localization denotes translocation
T7086 13965-13978 Localization denotes translocation
T7083 13986-13992 Protein denotes p65 NF
T7084 13993-13995 Protein denotes κB
T7089 14008-14016 Positive_regulation denotes enhanced
T7088 14008-14016 Positive_regulation denotes enhanced
T7090 14142-14146 Protein denotes IRF3
T7093 14162-14171 Positive_regulation denotes activated
T7091 14249-14265 Protein denotes IKK-like kinases
T7092 14266-14270 Protein denotes TBK1
T7094 14350-14357 Entity denotes nucleus
T7095 14450-14454 Protein denotes IRF3
T7096 14455-14470 Phosphorylation denotes phosphorylation
T7097 14577-14580 Protein denotes p65
T7098 14582-14586 Protein denotes IRF3
T7099 14587-14594 Entity denotes nuclear
T7100 14595-14608 Localization denotes translocation
T7101 14717-14722 Protein denotes NF-κB
T7111 14723-14731 Regulation denotes controls
T7110 14723-14731 Regulation denotes controls
T7108 14736-14746 Gene_expression denotes expression
T7107 14736-14746 Gene_expression denotes expression
T7102 14750-14754 Protein denotes IL-6
T7103 14759-14762 Protein denotes TNF
T7104 14768-14773 Protein denotes NF-κB
T7105 14778-14782 Protein denotes IRF3
T7113 14783-14790 Regulation denotes control
T7112 14783-14790 Regulation denotes control
T7109 14795-14805 Gene_expression denotes expression
T7106 14809-14813 Protein denotes IFNβ
T7128 14832-14840 Positive_regulation denotes enhanced
T7127 14832-14840 Positive_regulation denotes enhanced
T7120 14841-14851 Positive_regulation denotes activation
T7119 14841-14851 Positive_regulation denotes activation
T7114 14855-14860 Protein denotes NF-κB
T7115 14865-14869 Protein denotes IRF3
T7123 14906-14914 Localization denotes secreted
T7122 14906-14914 Localization denotes secreted
T7121 14906-14914 Localization denotes secreted
T7126 14915-14924 Positive_regulation denotes increased
T7125 14915-14924 Positive_regulation denotes increased
T7124 14915-14924 Positive_regulation denotes increased
T7116 14936-14940 Protein denotes IL-6
T7117 14942-14945 Protein denotes TNF
T7118 14950-14954 Protein denotes IFNβ
T7129 15158-15163 Protein denotes NF-κB
T7130 15168-15172 Protein denotes IRF3
T7132 15173-15183 Positive_regulation denotes activation
T7131 15173-15183 Positive_regulation denotes activation
T8415 15209-15212 Protein denotes A20
T8416 15251-15261 Gene_expression denotes expression
T8417 15297-15300 Protein denotes A20
T8418 15440-15448 Protein denotes A20 mRNA
T8419 15469-15476 Positive_regulation denotes induced
T8425 15595-15603 Positive_regulation denotes enhanced
T8424 15595-15603 Positive_regulation denotes enhanced
T8423 15604-15614 Gene_expression denotes expression
T8422 15604-15614 Gene_expression denotes expression
T8420 15618-15622 Protein denotes IL-6
T8421 15627-15631 Protein denotes IFNβ
T8426 15806-15809 Protein denotes TNF
T8427 15814-15818 Protein denotes IFNβ
T20678 15876-15879 Protein denotes A20
T20679 16122-16126 Protein denotes IL-6
T20680 16128-16132 Protein denotes IFNβ
T20681 16137-16145 Protein denotes A20 mRNA
T20684 16146-16156 Gene_expression denotes expression
T20683 16146-16156 Gene_expression denotes expression
T20682 16146-16156 Gene_expression denotes expression
T20685 16249-16252 Protein denotes TNF
T20686 16257-16269 Protein denotes IFNβ protein
T20687 16409-16413 Protein denotes IL-6
T20688 16418-16427 Protein denotes IFNβ mRNA
T20690 16428-16438 Gene_expression denotes expression
T20689 16428-16438 Gene_expression denotes expression
T20691 16509-16513 Protein denotes IL-6
T20692 16518-16530 Protein denotes IFNβ protein
T8443 17103-17113 Gene_expression denotes Expression
T8442 17103-17113 Gene_expression denotes Expression
T8441 17103-17113 Gene_expression denotes Expression
T8440 17103-17113 Gene_expression denotes Expression
T8439 17103-17113 Gene_expression denotes Expression
T8438 17103-17113 Gene_expression denotes Expression
T8437 17103-17113 Gene_expression denotes Expression
T8436 17103-17113 Gene_expression denotes Expression
T8446 17118-17127 Localization denotes secretion
T8445 17118-17127 Localization denotes secretion
T8444 17118-17127 Localization denotes secretion
T8428 17151-17165 Protein denotes cytokines IL-6
T8429 17170-17173 Protein denotes TNF
T8430 17179-17194 Protein denotes type-I IFN IFNβ
T8431 17199-17204 Protein denotes IFNα4
T8432 17213-17229 Protein denotes chemokines MCP-1
T8433 17231-17235 Protein denotes ccl2
T8434 17241-17243 Protein denotes KC
T8435 17245-17250 Protein denotes cxcl1
T8447 17421-17424 Protein denotes A20
T8448 17596-17601 Protein denotes NF-κB
T8449 17606-17610 Protein denotes IRF3
T8451 17611-17621 Positive_regulation denotes activation
T8450 17611-17621 Positive_regulation denotes activation
T11236 17624-17627 Protein denotes A20
T11237 17628-17638 Negative_regulation denotes deficiency
T11240 17709-17713 Regulation denotes role
T11238 17717-17720 Protein denotes A20
T11239 17721-17731 Gene_expression denotes expression
T21153 18967-18970 Protein denotes A20
T21154 18971-18981 Negative_regulation denotes deficiency
T21155 19409-19411 Protein denotes KC
T21156 19413-19418 Protein denotes MIP-2
T21157 19420-19425 Protein denotes MCP-1
T21158 19427-19431 Protein denotes IL-6
T21159 19436-19448 Protein denotes IFNα protein
T11241 19803-19806 Protein denotes A20
T11242 19807-19817 Negative_regulation denotes deficiency
T11243 20069-20073 Protein denotes IL-6
T11247 20311-20319 Positive_regulation denotes increase
T11244 20323-20328 Protein denotes MCP-1
T11245 20332-20336 Protein denotes IFNα
T11246 20337-20347 Gene_expression denotes production
T11248 20396-20398 Protein denotes KC
T11249 20427-20431 Protein denotes IL-8
T11250 20673-20675 Protein denotes KC
T11251 20680-20685 Protein denotes MIP-2
T11252 20740-20745 Protein denotes CD11b
T11253 20747-20752 Protein denotes Ly6C+
T11259 20975-20983 Positive_regulation denotes increase
T11258 20975-20983 Positive_regulation denotes increase
T11254 20997-21002 Protein denotes CD11b
T11255 21004-21008 Protein denotes Ly6C
T11257 21011-21022 Positive_regulation denotes recruitment
T11256 21011-21022 Positive_regulation denotes recruitment
T11260 21260-21265 Protein denotes CD11c
T11261 21267-21269 Protein denotes F4
T11262 21274-21279 Protein denotes CD11b
T11263 21502-21506 Protein denotes CD8+
T11264 21555-21558 Protein denotes A20
T11270 21559-21569 Gene_expression denotes expression
T11265 21631-21634 Protein denotes CD8
T11266 21648-21673 Protein denotes virus specific Granzyme B
T11267 21675-21678 Protein denotes GrB
T11268 21684-21688 Protein denotes IFNγ
T11273 21689-21699 Gene_expression denotes expressing
T11272 21689-21699 Gene_expression denotes expressing
T11271 21689-21699 Gene_expression denotes expressing
T11269 21700-21704 Protein denotes CD8+
T11274 21808-21812 Protein denotes CD8+
T11275 21991-21994 Protein denotes GrB
T11276 21999-22007 Protein denotes IFNγ CD8
T11277 22028-22032 Protein denotes IFNγ
T11278 22033-22043 Gene_expression denotes expression
T11279 22073-22080 Regulation denotes altered
T11280 22311-22324 Protein denotes hemagglutinin
T11281 22326-22328 Protein denotes HA
T11282 23676-23678 Protein denotes KC
T11283 23683-23688 Protein denotes MIP-2
T11285 23689-23699 Gene_expression denotes production
T11284 23689-23699 Gene_expression denotes production
T11291 23910-23916 Gene_expression denotes levels
T11290 23910-23916 Gene_expression denotes levels
T11289 23910-23916 Gene_expression denotes levels
T11286 23940-23954 Protein denotes cytokines IL-6
T11287 23956-23959 Protein denotes TNF
T11288 23964-23969 Protein denotes IL-1β
T11294 24043-24052 Positive_regulation denotes increased
T11293 24043-24052 Positive_regulation denotes increased
T11292 24043-24052 Positive_regulation denotes increased
T11295 24474-24477 Protein denotes A20
T11296 24478-24488 Negative_regulation denotes deficiency
T21582 24652-24655 Protein denotes A20
T21583 24656-24666 Negative_regulation denotes deficiency
T21584 25057-25059 Protein denotes KC
T21585 25061-25066 Protein denotes MIP-2
T21586 25068-25073 Protein denotes MCP-1
T21587 25075-25079 Protein denotes IL-6
T21588 25084-25096 Protein denotes IFNα protein
T14426 25470-25473 Protein denotes A20
T14427 25474-25484 Gene_expression denotes expression
T14429 26165-26174 Gene_expression denotes producers
T14428 26178-26189 Protein denotes type I IFNs
T14431 26433-26440 Gene_expression denotes express
T14430 26485-26496 Protein denotes type I IFNs
T14432 26677-26679 Protein denotes KC
T14433 26684-26689 Protein denotes MIP-2
T14434 26736-26740 Protein denotes IL-6
T14435 26742-26745 Protein denotes TNF
T14436 26750-26755 Protein denotes IL-1β
T14437 28138-28142 Protein denotes Ly6C
T14438 28144-28149 Protein denotes CD11b
T14445 28342-28350 Positive_regulation denotes enhanced
T14444 28342-28350 Positive_regulation denotes enhanced
T14439 28351-28356 Protein denotes NF-κB
T14440 28361-28365 Protein denotes IRF3
T14443 28366-28376 Positive_regulation denotes activation
T14442 28366-28376 Positive_regulation denotes activation
T14441 28392-28397 Protein denotes RIG-I
T14446 28647-28652 Protein denotes RIG-I
T14457 28684-28692 Negative_regulation denotes inhibits
T14456 28684-28692 Negative_regulation denotes inhibits
T14447 28769-28772 Protein denotes TNF
T14448 28774-28778 Protein denotes IL-6
T14449 28780-28782 Protein denotes KC
T14450 28784-28789 Protein denotes MIP-2
T14451 28795-28799 Protein denotes IFNβ
T14452 28826-28831 Protein denotes NF-κB
T14453 28836-28840 Protein denotes IRF3
T14455 28841-28851 Positive_regulation denotes activation
T14454 28841-28851 Positive_regulation denotes activation
T14458 29050-29053 Protein denotes A20
T14459 29079-29084 Protein denotes NF-κB
T14460 29089-29093 Protein denotes IRF3
T14461 29261-29270 Protein denotes ubiquitin
T14467 29271-29278 Binding denotes binding
T14462 29288-29295 Protein denotes TAX1BP1
T14463 29300-29305 Protein denotes ABIN1
T14464 29324-29329 Protein denotes TRAF3
T14465 29330-29334 Protein denotes TBK1
T14466 29404-29408 Protein denotes TBK1
T14468 29527-29532 Protein denotes RIG-I
T14469 29541-29546 Protein denotes NF-κB
T14470 29634-29647 Protein denotes TBK1 and IKKε
T14471 29714-29717 Protein denotes A20
T14472 29718-29728 Negative_regulation denotes deficiency
T14473 29796-29799 Protein denotes A20
T14479 29835-29842 Positive_regulation denotes mediate
T14478 29835-29842 Positive_regulation denotes mediate
T14474 29843-29848 Protein denotes NF-κB
T14475 29853-29857 Protein denotes IRF3
T14477 29858-29868 Positive_regulation denotes activation
T14476 29858-29868 Positive_regulation denotes activation
T14480 30143-30148 Protein denotes RIG-I
T14481 30162-30167 Protein denotes NF-κB
T14482 30172-30177 Protein denotes IRF-3
T14483 30406-30409 Protein denotes A20
T14485 30410-30420 Gene_expression denotes expression
T14484 30465-30470 Protein denotes RIG-I
T14486 30610-30613 Protein denotes A20
T14487 31854-31857 Protein denotes A20
T14490 31989-31998 Localization denotes targeting
T14488 32002-32005 Protein denotes A20
T14489 32090-32106 Protein denotes SARS coronavirus
T15241 32758-32762 Protein denotes LysM
T15242 32763-32766 Protein denotes Cre
T15243 33201-33205 Protein denotes LysM
T15244 33206-33209 Protein denotes Cre
T15245 33254-33261 Protein denotes C57Bl/6
T15247 33288-33298 Gene_expression denotes expressing
T15248 33302-33309 Negative_regulation denotes lacking
T15246 33314-33332 Protein denotes LysM-Cre transgene
T15644 33517-33521 Protein denotes MDCK
T15645 34087-34094 Protein denotes trypsin
T16044 34442-34445 Protein denotes HAI
T16045 35078-35081 Protein denotes RBC
T16046 35154-35165 Protein denotes PBS instead
T16047 35209-35212 Protein denotes PR8
T16445 35397-35400 Protein denotes GrB
T16446 35405-35409 Protein denotes IFNγ
T16449 35410-35418 Gene_expression denotes staining
T16448 35410-35418 Gene_expression denotes staining
T16447 35432-35436 Protein denotes CD8+
T16450 35445-35455 Protein denotes Granzyme B
T16451 35457-35460 Protein denotes GrB
T16452 35466-35470 Protein denotes IFNγ
T16458 35471-35481 Gene_expression denotes expressing
T16457 35471-35481 Gene_expression denotes expressing
T16456 35471-35481 Gene_expression denotes expressing
T16453 35482-35486 Protein denotes CD8+
T16454 35556-35567 Protein denotes Brefeldin A
T16455 35569-35574 Protein denotes Sigma
T16459 35728-35739 Protein denotes Brefeldin A
T16460 35876-35880 Protein denotes CD8+
T16461 35930-35940 Protein denotes CD62lo CD3
T16462 35946-35950 Protein denotes CD8+
T16464 35951-35961 Gene_expression denotes expression
T16463 35951-35961 Gene_expression denotes expression
T17092 36108-36112 Protein denotes MDCK
T17110 36336-36346 Gene_expression denotes expression
T17109 36336-36346 Gene_expression denotes expression
T17108 36336-36346 Gene_expression denotes expression
T17107 36336-36346 Gene_expression denotes expression
T17106 36336-36346 Gene_expression denotes expression
T17105 36336-36346 Gene_expression denotes expression
T17104 36336-36346 Gene_expression denotes expression
T17103 36336-36346 Gene_expression denotes expression
T17102 36336-36346 Gene_expression denotes expression
T17093 36416-36428 Protein denotes pEF-HA-IRF-7
T17094 36539-36544 Protein denotes NF-κB
T17095 36546-36550 Protein denotes IRF3
T17096 36552-36556 Protein denotes IRF7
T17097 36609-36618 Protein denotes pISRE-luc
T17098 36620-36628 Protein denotes LMBP4011
T17099 36631-36645 Protein denotes pGL3-IFNα4-luc
T17100 36728-36739 Protein denotes pACTbetagal
T17101 36741-36749 Protein denotes LMBP4341
T17111 37201-37206 Protein denotes CD11b
T17724 37676-37700 Protein denotes protease and phosphatase
T17725 37701-37711 Negative_regulation denotes inhibitors
T17726 37864-37914 Protein denotes mM EGTA supplemented with protease and phosphatase
T17727 38215-38265 Protein denotes mM EGTA supplemented with protease and phosphatase
T17728 38461-38469 Protein denotes anti-A20
T17729 38471-38480 Protein denotes anti-IκBα
T17730 38482-38490 Protein denotes anti-p65
T17731 38496-38510 Protein denotes anti-histon H1
T17732 38549-38566 Protein denotes anti-phospho-IRF3
T17733 38571-38605 Protein denotes anti-phospho-IκBα (Cell Signaling)
T17734 38610-38620 Protein denotes anti-actin
T18174 38886-38897 Protein denotes collagenase
T18175 39259-39264 Protein denotes CD11c
T18176 39302-39307 Protein denotes CD62L
T18177 39409-39426 Protein denotes Ly6C Horizon v450
T18178 39436-39443 Protein denotes Ly6G PE
T18179 39445-39448 Protein denotes 1A8
T18180 39451-39456 Protein denotes CD11b
T18181 39474-39509 Protein denotes CD8α PerCP (53-6.7), IFNγ Alexa 647
T18182 39544-39557 Protein denotes BD Pharmingen
T18557 39757-39766 Protein denotes TNF ELISA
T18558 39800-39803 Protein denotes TNF
T18559 39882-39903 Protein denotes IFNα and IFNβ protein
T18560 39980-39990 Protein denotes IFNγ ELISA
T18570 40096-40105 Gene_expression denotes Detection
T18569 40096-40105 Gene_expression denotes Detection
T18568 40096-40105 Gene_expression denotes Detection
T18567 40096-40105 Gene_expression denotes Detection
T18566 40096-40105 Gene_expression denotes Detection
T18561 40109-40114 Protein denotes MCP-1
T18562 40116-40118 Protein denotes KC
T18563 40120-40123 Protein denotes TNF
T18564 40125-40130 Protein denotes IL-1β
T18565 40135-40139 Protein denotes IL-6
T18571 40310-40315 Protein denotes MIP-2
T19045 40473-40485 Protein denotes iScript cDNA
T19046 40486-40495 Gene_expression denotes synthesis
T19051 40577-40582 Gene_expression denotes using
T19047 40588-40608 Protein denotes Green I master mix I
T19048 40831-40835 Protein denotes IFNβ
T19049 41037-41042 Protein denotes CXCL1
T19050 41106-41111 Protein denotes IFNα4
T19053 41332-41341 Gene_expression denotes expressed
T19052 41354-41358 Protein denotes HPRT
R10868 T14426 T14427 themeOf A20,expression
R10871 T14428 T14429 themeOf type I IFNs,producers
R10874 T14430 T14431 themeOf type I IFNs,express
R10876 T14439 T14442 themeOf NF-κB,activation
R10877 T14440 T14443 themeOf IRF3,activation
R10878 T14442 T14444 themeOf activation,enhanced
R10879 T14443 T14445 themeOf activation,enhanced
R10880 T14452 T14454 themeOf NF-κB,activation
R10883 T14453 T14455 themeOf IRF3,activation
R10885 T14454 T14456 themeOf activation,inhibits
R10886 T14455 T14457 themeOf activation,inhibits
R10887 T14461 T14467 themeOf ubiquitin,binding
R10888 T14463 T14467 themeOf ABIN1,binding
R10891 T14471 T14472 themeOf A20,deficiency
R10894 T14474 T14476 themeOf NF-κB,activation
R10899 T14475 T14477 themeOf IRF3,activation
R10900 T14476 T14478 themeOf activation,mediate
R10902 T14477 T14479 themeOf activation,mediate
R10904 T14483 T14485 themeOf A20,expression
R10906 T14488 T14490 themeOf A20,targeting
R11386 T15246 T15247 themeOf LysM-Cre transgene,expressing
R11387 T15246 T15248 themeOf LysM-Cre transgene,lacking
R12403 T16445 T16448 themeOf GrB,staining
R12404 T16446 T16449 themeOf IFNγ,staining
R12405 T16450 T16456 themeOf Granzyme B,expressing
R12406 T16451 T16457 themeOf GrB,expressing
R12407 T16452 T16458 themeOf IFNγ,expressing
R12408 T16461 T16463 themeOf CD62lo CD3,expression
R12409 T16462 T16464 themeOf CD8+,expression
R12929 T17093 T17102 themeOf pEF-HA-IRF-7,expression
R12930 T17094 T17103 themeOf NF-κB,expression
R12931 T17095 T17104 themeOf IRF3,expression
R12932 T17096 T17105 themeOf IRF7,expression
R12933 T17097 T17106 themeOf pISRE-luc,expression
R12934 T17098 T17107 themeOf LMBP4011,expression
R12935 T17099 T17108 themeOf pGL3-IFNα4-luc,expression
R12936 T17100 T17109 themeOf pACTbetagal,expression
R12937 T17101 T17110 themeOf LMBP4341,expression
R13503 T17724 T17725 themeOf protease and phosphatase,inhibitors
R14008 T18561 T18566 themeOf MCP-1,Detection
R14009 T18562 T18567 themeOf KC,Detection
R14010 T18563 T18568 themeOf TNF,Detection
R14011 T18564 T18569 themeOf IL-1β,Detection
R14012 T18565 T18570 themeOf IL-6,Detection
R14342 T19045 T19046 themeOf iScript cDNA,synthesis
R14343 T19047 T19051 themeOf Green I master mix I,using
R14344 T19052 T19053 themeOf HPRT,expressed
R15073 T20072 T20075 themeOf NF-κB,activation
R15074 T20073 T20076 themeOf IRF3,activation
R15075 T20075 T20077 themeOf activation,inhibits
R15076 T20076 T20078 themeOf activation,inhibits
R15077 T20077 T20071 Cause inhibits,A20
R15078 T20078 T20071 Cause inhibits,A20
R15079 T20079 T20084 themeOf NF-κB,transfected
R15080 T20080 T20085 themeOf IRF3,transfected
R15081 T20082 T20086 themeOf IRF7,expressing
R15082 T20083 T20087 themeOf A20,expressing
R15083 T20089 T20091 themeOf IκBα,phosphorylation
R15084 T20089 T20092 themeOf IκBα,degradation
R15085 T20090 T20093 themeOf IRF3,phosphorylation
R15086 T20094 T20095 themeOf anti-IκBα antibody,recognized
R15087 T20096 T20100 themeOf NF-κB,translocation
R15088 T20097 T20101 themeOf p65,translocation
R15089 T20098 T20102 themeOf IRF3,translocation
R15090 T20100 T20099 ToLoc translocation,Nuclear
R15091 T20101 T20099 ToLoc translocation,Nuclear
R15092 T20102 T20099 ToLoc translocation,Nuclear
R15093 T20103 T20105 themeOf p65,expressed
R15094 T20104 T20106 themeOf IRF3,expressed
R15095 T20107 T20113 themeOf IL-6,levels
R15096 T20108 T20114 themeOf TNF,levels
R15097 T20109 T20115 themeOf IFNβ,levels
R15479 T20679 T20682 themeOf IL-6,expression
R15480 T20680 T20683 themeOf IFNβ,expression
R15481 T20681 T20684 themeOf A20 mRNA,expression
R15482 T20687 T20689 themeOf IL-6,expression
R15483 T20688 T20690 themeOf IFNβ mRNA,expression
R15839 T21153 T21154 themeOf A20,deficiency
R16160 T21582 T21583 themeOf A20,deficiency
R3002 T3886 T3897 themeOf TNF,production
R3003 T3887 T3898 themeOf IL-6,production
R3004 T3888 T3899 themeOf IL-1,production
R3005 T3889 T3900 themeOf type I interferons,production
R3006 T3890 T3901 themeOf interferon-α,production
R3007 T3891 T3902 themeOf IFN-α,production
R3008 T3892 T3903 themeOf IFN-β,production
R3009 T3928 T3929 themeOf type I IFN,producing
R3010 T3897 T3904 themeOf production,induces
R3011 T3933 T3934 themeOf TLR3,deficient
R3012 T3898 T3905 themeOf production,induces
R3013 T3936 T3939 themeOf CARD domains,binding
R3014 T3936 T3941 themeOf CARD domains,binding
R3015 T3937 T3940 themeOf RIG-I,binding
R3016 T3937 T3941 themeOf RIG-I,binding
R3017 T3937 T3942 themeOf RIG-I,associate
R3018 T3938 T3942 themeOf CARD domain,associate
R3019 T3899 T3906 themeOf production,induces
R3020 T3900 T3907 themeOf production,induces
R3021 T3901 T3908 themeOf production,induces
R3022 T3946 T3949 themeOf K63-specific ubiquitin ligases,promote
R3023 T3947 T3950 themeOf E3s,promote
R3024 T3902 T3909 themeOf production,induces
R3025 T3948 T3951 themeOf RIG-I,activation
R3026 T3903 T3910 themeOf production,induces
R3027 T3924 T3926 themeOf PYHIN domain,containing
R3028 T3953 T3956 themeOf NF-κB,activation
R3029 T3954 T3957 themeOf IRF3,activation
R3030 T3956 T3958 themeOf activation,mediate
R3031 T3957 T3959 themeOf activation,mediate
R3032 T3958 T3952 Cause mediate,ubiquitin ligases
R3033 T3959 T3952 Cause mediate,ubiquitin ligases
R3034 T3961 T3963 themeOf K48-specific ubiquitin ligases,degradation
R3035 T3962 T3964 themeOf TRAF3,degradation
R3036 T3925 T3927 themeOf IFI16,containing
R455 T561 T563 themeOf A20,Deficiency
R456 T562 T564 themeOf Tnfaip3,Deficiency
R457 T566 T567 themeOf interferon,production
R458 T567 T568 themeOf production,induces
R459 T569 T571 themeOf ubiquitin-editing protein,role
R460 T570 T572 themeOf A20,role
R461 T573 T576 themeOf NF-κB,activation
R462 T574 T577 themeOf IRF3,activation
R463 T575 T578 themeOf type I interferon,production
R464 T576 T579 themeOf activation,enhanced
R465 T577 T580 themeOf activation,enhanced
R466 T578 T581 themeOf production,increased
R467 T582 T583 themeOf A20,inhibition
R5042 T6977 T6979 themeOf NF-κB,activation
R5045 T6979 T6980 themeOf activation,inhibits
R5046 T6979 T6981 themeOf activation,RIG-I-induced
R5047 T6981 T6982 themeOf RIG-I-induced,activation
R5050 T6984 T6988 themeOf NF-κB,activation
R5052 T6985 T6989 themeOf IRF3,activation
R5053 T6986 T6990 themeOf IRF7 transcription factors,activation
R5055 T6987 T6991 themeOf type I IFNs,expression
R5056 T6988 T6992 themeOf activation,induces
R5058 T6989 T6993 themeOf activation,induces
R5059 T6990 T6994 themeOf activation,induces
R5060 T6991 T6995 themeOf expression,promote
R5061 T6991 T6996 themeOf expression,promote
R5062 T6991 T6997 themeOf expression,promote
R5065 T6995 T6984 Cause promote,NF-κB
R5067 T6996 T6985 Cause promote,IRF3
R5068 T6997 T6986 Cause promote,IRF7 transcription factors
R5069 T6998 T7002 themeOf A20,expressed
R5070 T6999 T7003 themeOf NF-κB,activation
R5072 T7000 T7004 themeOf IRF3,activation
R5077 T7003 T7005 themeOf activation,regulates
R5078 T7004 T7006 themeOf activation,regulates
R5081 T7007 T7011 themeOf A20,overexpression
R5082 T7010 T7013 themeOf luciferase,induced
R5083 T7011 T7012 themeOf overexpression,overexpression
R5085 T7014 T7015 themeOf IRF7,activation
R5086 T7015 T7016 themeOf activation,inhibits
R5088 T7017 T7021 themeOf IRF3,expressed
R5089 T7018 T7022 themeOf IRF7,expressed
R5091 T7020 T7023 themeOf IRF3,activation
R5092 T7023 T7024 themeOf activation,upregulated
R5094 T7026 T7030 themeOf IRF7,transfected
R5095 T7026 T7034 themeOf IRF7,expression
R5096 T7027 T7031 themeOf A20,transfected
R5098 T7030 T7032 themeOf transfected,transfected
R5099 T7031 T7033 themeOf transfected,transfected
R5101 T7035 T7038 themeOf IRF7,co-expression
R5102 T7036 T7039 themeOf IFNα4 promoter,activation
R5103 T7040 T7044 themeOf NF-κB,activation
R5104 T7086 T7085 ToLoc translocation,nuclear
R5105 T7041 T7045 themeOf IRF3,activation
R5106 T7043 T7046 themeOf IRF7,activation
R5107 T7086 T7088 themeOf translocation,enhanced
R5108 T7044 T7047 themeOf activation,effect
R5109 T7045 T7048 themeOf activation,effect
R5110 T7087 T7085 ToLoc translocation,nuclear
R5111 T7087 T7089 themeOf translocation,enhanced
R5112 T7046 T7049 themeOf activation,prevented
R5113 T7090 T7093 themeOf IRF3,activated
R5114 T7049 T7042 Cause prevented,A20
R5115 T7050 T7052 themeOf NF-κB,activation
R5116 T7051 T7053 themeOf IRF3/7,activation
R5117 T7093 T7092 Cause activated,TBK1
R5118 T7052 T7054 themeOf activation,inhibit
R5119 T7053 T7055 themeOf activation,inhibit
R5120 T7095 T7096 themeOf IRF3,phosphorylation
R5121 T7057 T7059 themeOf Cre recombinase,expressing
R5122 T7059 T7060 themeOf expressing,control
R5123 T7098 T7100 themeOf IRF3,translocation
R5124 T7060 T7058 Cause control,lysozyme M promoter
R5125 T7061 T7063 themeOf RIG-I receptor,stimulate
R5126 T7062 T7064 themeOf RIG-I,activate
R5127 T7100 T7099 ToLoc translocation,nuclear
R5128 T7065 T7067 themeOf TLR3 dependent NF-κB,activation
R5129 T7066 T7068 themeOf IRF3,activation
R5130 T7067 T7069 themeOf activation,induce
R5131 T7102 T7107 themeOf IL-6,expression
R5132 T7068 T7070 themeOf activation,induce
R5133 T7071 T7072 themeOf A20,expression
R5134 T7103 T7108 themeOf TNF,expression
R5135 T7072 T7073 themeOf expression,induced
R5136 T7074 T7076 themeOf NF-κB,activation
R5137 T7106 T7109 themeOf IFNβ,expression
R5138 T7075 T7077 themeOf IκBα,phosphorylation
R5139 T7075 T7078 themeOf IκBα,degradation
R5140 T7076 T7079 themeOf activation,enhanced
R5141 T7077 T7081 themeOf phosphorylation,increased
R5142 T7078 T7082 themeOf degradation,increased
R5143 T7079 T7080 themeOf enhanced,activation
R5144 T7083 T7086 themeOf p65 NF,translocation
R5145 T7107 T7110 themeOf expression,controls
R5146 T7084 T7087 themeOf κB,translocation
R5147 T7108 T7111 themeOf expression,controls
R5148 T7109 T7112 themeOf expression,control
R5149 T7109 T7113 themeOf expression,control
R5150 T7110 T7101 Cause controls,NF-κB
R5151 T7111 T7101 Cause controls,NF-κB
R5152 T7112 T7104 Cause control,NF-κB
R5155 T7113 T7105 Cause control,IRF3
R5158 T7114 T7119 themeOf NF-κB,activation
R5159 T7115 T7120 themeOf IRF3,activation
R5160 T7116 T7121 themeOf IL-6,secreted
R5163 T7116 T7124 themeOf IL-6,increased
R5165 T7117 T7122 themeOf TNF,secreted
R5169 T7117 T7125 themeOf TNF,increased
R5171 T7118 T7123 themeOf IFNβ,secreted
R5178 T7118 T7126 themeOf IFNβ,increased
R5179 T7119 T7127 themeOf activation,enhanced
R5181 T7120 T7128 themeOf activation,enhanced
R5184 T7129 T7131 themeOf NF-κB,activation
R5194 T7130 T7132 themeOf IRF3,activation
R6014 T8415 T8416 themeOf A20,expression
R6015 T8418 T8419 themeOf A20 mRNA,induced
R6016 T8420 T8422 themeOf IL-6,expression
R6017 T8421 T8423 themeOf IFNβ,expression
R6018 T8422 T8424 themeOf expression,enhanced
R6019 T8423 T8425 themeOf expression,enhanced
R6020 T8428 T8436 themeOf cytokines IL-6,Expression
R6021 T8429 T8437 themeOf TNF,Expression
R6022 T8429 T8444 themeOf TNF,secretion
R6023 T8430 T8438 themeOf type-I IFN IFNβ,Expression
R6024 T8431 T8439 themeOf IFNα4,Expression
R6025 T8432 T8440 themeOf chemokines MCP-1,Expression
R6026 T8432 T8445 themeOf chemokines MCP-1,secretion
R6027 T8433 T8441 themeOf ccl2,Expression
R6028 T8434 T8442 themeOf KC,Expression
R6029 T8434 T8446 themeOf KC,secretion
R6030 T8435 T8443 themeOf cxcl1,Expression
R6031 T8448 T8450 themeOf NF-κB,activation
R6032 T8449 T8451 themeOf IRF3,activation
R8396 T11236 T11237 themeOf A20,deficiency
R8398 T11238 T11239 themeOf A20,expression
R8399 T11239 T11240 themeOf expression,role
R8401 T11241 T11242 themeOf A20,deficiency
R8402 T11245 T11246 themeOf IFNα,production
R8403 T11246 T11247 themeOf production,increase
R8406 T11254 T11256 themeOf CD11b,recruitment
R8407 T11255 T11257 themeOf Ly6C,recruitment
R8408 T11256 T11258 themeOf recruitment,increase
R8409 T11257 T11259 themeOf recruitment,increase
R8410 T11264 T11270 themeOf A20,expression
R8412 T11266 T11271 themeOf virus specific Granzyme B,expressing
R8413 T11268 T11272 themeOf IFNγ,expressing
R8415 T11269 T11273 themeOf CD8+,expressing
R8418 T11277 T11278 themeOf IFNγ,expression
R8419 T11278 T11279 themeOf expression,altered
R8421 T11282 T11284 themeOf KC,production
R8422 T11283 T11285 themeOf MIP-2,production
R8423 T11286 T11289 themeOf cytokines IL-6,levels
R8424 T11287 T11290 themeOf TNF,levels
R8426 T11288 T11291 themeOf IL-1β,levels
R8427 T11289 T11292 themeOf levels,increased
R8429 T11290 T11293 themeOf levels,increased
R8430 T11291 T11294 themeOf levels,increased
R8431 T11295 T11296 themeOf A20,deficiency