Id |
Subject |
Object |
Predicate |
Lexical cue |
T19621 |
11-16 |
Protein |
denotes |
IL-17 |
T19622 |
246-250 |
Protein |
denotes |
IL-1 |
T19623 |
255-260 |
Protein |
denotes |
TNF-α |
T19624 |
347-351 |
Protein |
denotes |
IL-4 |
T19625 |
356-368 |
Protein |
denotes |
interferon-γ |
T19632 |
982-991 |
Positive_regulation |
denotes |
stimulate |
T19626 |
992-997 |
Protein |
denotes |
IL-17 |
T19630 |
998-1008 |
Gene_expression |
denotes |
production |
T19627 |
1046-1051 |
Protein |
denotes |
IL-17 |
T19631 |
1052-1062 |
Gene_expression |
denotes |
production |
T19628 |
1087-1090 |
Protein |
denotes |
CD3 |
T19629 |
1096-1100 |
Protein |
denotes |
CD28 |
T19633 |
1195-1198 |
Protein |
denotes |
CD3 |
T19634 |
1199-1208 |
Protein |
denotes |
anti-CD28 |
T19635 |
1235-1250 |
Protein |
denotes |
T cell receptor |
T19637 |
1388-1400 |
Positive_regulation |
denotes |
upregulation |
T19636 |
1404-1409 |
Protein |
denotes |
IL-17 |
T19638 |
1493-1498 |
Protein |
denotes |
IL-17 |
T19640 |
1502-1510 |
Gene_expression |
denotes |
produced |
T19639 |
1531-1534 |
Protein |
denotes |
CD4 |
T19641 |
1639-1643 |
Protein |
denotes |
CD8+ |
T19645 |
1777-1786 |
Positive_regulation |
denotes |
augmented |
T19644 |
1798-1809 |
Binding |
denotes |
recognizing |
T19642 |
1810-1826 |
Protein |
denotes |
type II collagen |
T19643 |
1832-1840 |
Protein |
denotes |
collagen |
T19651 |
2102-2109 |
Localization |
denotes |
secrete |
T19650 |
2102-2109 |
Localization |
denotes |
secrete |
T19649 |
2102-2109 |
Localization |
denotes |
secrete |
T19646 |
2136-2140 |
Protein |
denotes |
IL-6 |
T19647 |
2142-2146 |
Protein |
denotes |
IL-8 |
T19648 |
2151-2190 |
Protein |
denotes |
tumor necrosis factor-stimulated gene 6 |
T19654 |
2295-2304 |
Positive_regulation |
denotes |
stimulate |
T19652 |
2305-2310 |
Protein |
denotes |
IL-17 |
T19653 |
2311-2321 |
Gene_expression |
denotes |
production |
T19662 |
2464-2474 |
Gene_expression |
denotes |
production |
T19661 |
2464-2474 |
Gene_expression |
denotes |
production |
T19655 |
2478-2483 |
Protein |
denotes |
IL-17 |
T19656 |
2487-2494 |
Protein |
denotes |
RA PBMC |
T19657 |
2567-2582 |
Protein |
denotes |
T cell receptor |
T19658 |
2584-2587 |
Protein |
denotes |
TCR |
T19664 |
2589-2597 |
Binding |
denotes |
ligation |
T19663 |
2589-2597 |
Binding |
denotes |
ligation |
T19659 |
2609-2612 |
Protein |
denotes |
CD3 |
T19660 |
2613-2622 |
Protein |
denotes |
anti-CD28 |
T19665 |
2654-2659 |
Protein |
denotes |
IL-15 |
T19666 |
2664-2669 |
Protein |
denotes |
MCP-1 |
T19667 |
2681-2684 |
Protein |
denotes |
TCR |
T19671 |
2685-2693 |
Binding |
denotes |
ligation |
T19670 |
2685-2693 |
Binding |
denotes |
ligation |
T19681 |
2708-2717 |
Positive_regulation |
denotes |
increased |
T19680 |
2708-2717 |
Positive_regulation |
denotes |
increased |
T19679 |
2708-2717 |
Positive_regulation |
denotes |
increased |
T19678 |
2708-2717 |
Positive_regulation |
denotes |
increased |
T19677 |
2708-2717 |
Positive_regulation |
denotes |
increased |
T19676 |
2708-2717 |
Positive_regulation |
denotes |
increased |
T19675 |
2708-2717 |
Positive_regulation |
denotes |
increased |
T19674 |
2708-2717 |
Positive_regulation |
denotes |
increased |
T19673 |
2722-2732 |
Gene_expression |
denotes |
production |
T19672 |
2722-2732 |
Gene_expression |
denotes |
production |
T19668 |
2736-2741 |
Protein |
denotes |
IL-17 |
T19669 |
2745-2752 |
Protein |
denotes |
RA PBMC |
T19682 |
2761-2766 |
Protein |
denotes |
IL-15 |
T19683 |
2770-2775 |
Protein |
denotes |
MCP-1 |
T19684 |
2779-2782 |
Protein |
denotes |
TCR |
T19685 |
2783-2791 |
Binding |
denotes |
ligation |
T19686 |
2847-2851 |
Protein |
denotes |
IL-1 |
T19687 |
2856-2861 |
Protein |
denotes |
TNF-α |
T19691 |
2956-2962 |
Regulation |
denotes |
affect |
T19690 |
2956-2962 |
Regulation |
denotes |
affect |
T19688 |
2963-2968 |
Protein |
denotes |
IL-17 |
T19689 |
2969-2979 |
Gene_expression |
denotes |
production |
T19692 |
3032-3037 |
Protein |
denotes |
IL-15 |
T19693 |
3087-3092 |
Protein |
denotes |
TNF-α |
T19694 |
3366-3379 |
Protein |
denotes |
anti-CD3/anti |
T19695 |
3380-3384 |
Protein |
denotes |
CD28 |
T19701 |
3390-3399 |
Positive_regulation |
denotes |
increases |
T19700 |
3390-3399 |
Positive_regulation |
denotes |
increases |
T19696 |
3400-3405 |
Protein |
denotes |
IL-17 |
T19699 |
3406-3415 |
Positive_regulation |
denotes |
induction |
T19698 |
3406-3415 |
Positive_regulation |
denotes |
induction |
T19697 |
3419-3426 |
Protein |
denotes |
RA PBMC |
T19702 |
3504-3509 |
Protein |
denotes |
IL-17 |
T19703 |
3583-3588 |
Protein |
denotes |
IL-17 |
T19704 |
3589-3599 |
Gene_expression |
denotes |
production |
T19705 |
3607-3616 |
Regulation |
denotes |
regulated |
T19708 |
3762-3771 |
Positive_regulation |
denotes |
induction |
T19706 |
3775-3780 |
Protein |
denotes |
IL-17 |
T19707 |
3784-3791 |
Protein |
denotes |
RA PBMC |
T19709 |
3817-3820 |
Protein |
denotes |
CD3 |
T19716 |
3821-3828 |
Positive_regulation |
denotes |
induced |
T19714 |
3835-3845 |
Gene_expression |
denotes |
production |
T19710 |
3849-3856 |
Protein |
denotes |
RA PBMC |
T19715 |
3875-3883 |
Positive_regulation |
denotes |
hampered |
T19711 |
3891-3895 |
Protein |
denotes |
PI3K |
T19712 |
3906-3914 |
Protein |
denotes |
LY294002 |
T19713 |
3923-3928 |
Protein |
denotes |
NF-κB |
T19717 |
4030-4033 |
Protein |
denotes |
CD3 |
T19718 |
4108-4116 |
Protein |
denotes |
p38 MAPK |
T19719 |
4117-4126 |
Negative_regulation |
denotes |
inhibitor |
T19720 |
4199-4204 |
Protein |
denotes |
NF-κB |
T19721 |
4209-4212 |
Protein |
denotes |
p38 |
T19722 |
4227-4239 |
Protein |
denotes |
IκB kinase-β |
T19727 |
4243-4252 |
Positive_regulation |
denotes |
activated |
T19728 |
4274-4283 |
Positive_regulation |
denotes |
activated |
T19723 |
4284-4287 |
Protein |
denotes |
p38 |
T19729 |
4292-4301 |
Positive_regulation |
denotes |
stimulate |
T19724 |
4302-4307 |
Protein |
denotes |
NF-κB |
T19725 |
4333-4355 |
Protein |
denotes |
histone acetylase p300 |
T19726 |
4356-4360 |
Protein |
denotes |
CREB |
T19730 |
4361-4368 |
Binding |
denotes |
binding |
T19731 |
4409-4417 |
Protein |
denotes |
p38 MAPK |
T19735 |
4418-4428 |
Positive_regulation |
denotes |
activation |
T19736 |
4437-4445 |
Regulation |
denotes |
affected |
T19732 |
4467-4472 |
Protein |
denotes |
NF-κB |
T19737 |
4473-4480 |
Binding |
denotes |
binding |
T19738 |
4494-4503 |
Negative_regulation |
denotes |
decreased |
T19733 |
4551-4554 |
Protein |
denotes |
p38 |
T19734 |
4583-4587 |
Protein |
denotes |
PI3K |
T19739 |
4588-4598 |
Positive_regulation |
denotes |
activation |
T19740 |
4632-4635 |
Protein |
denotes |
p38 |
T19741 |
4640-4645 |
Protein |
denotes |
NF-κB |
T19742 |
4650-4655 |
Protein |
denotes |
IL-17 |
T19743 |
4656-4666 |
Gene_expression |
denotes |
production |
T19744 |
4749-4753 |
Protein |
denotes |
PI3K |
T19745 |
4791-4794 |
Protein |
denotes |
Akt |
T19746 |
4795-4805 |
Positive_regulation |
denotes |
activation |
T19747 |
4830-4834 |
Negative_regulation |
denotes |
loss |
T19748 |
4873-4876 |
Protein |
denotes |
Akt |
T19752 |
4880-4894 |
Phosphorylation |
denotes |
phosphorylated |
T19749 |
4905-4908 |
Protein |
denotes |
CD3 |
T19754 |
4943-4954 |
Regulation |
denotes |
involvement |
T19750 |
4958-4962 |
Protein |
denotes |
PI3K |
T19753 |
4970-4979 |
Positive_regulation |
denotes |
induction |
T19751 |
4983-4988 |
Protein |
denotes |
IL-17 |
T19755 |
5021-5026 |
Protein |
denotes |
NF-κB |
T19764 |
5036-5045 |
Positive_regulation |
denotes |
activated |
T19763 |
5036-5045 |
Positive_regulation |
denotes |
activated |
T19762 |
5036-5045 |
Positive_regulation |
denotes |
activated |
T19756 |
5049-5057 |
Protein |
denotes |
anti-CD3 |
T19757 |
5058-5067 |
Protein |
denotes |
anti-CD28 |
T19758 |
5069-5074 |
Protein |
denotes |
IL-15 |
T19759 |
5134-5139 |
Protein |
denotes |
NF-κB |
T19768 |
5165-5173 |
Regulation |
denotes |
involved |
T19767 |
5165-5173 |
Regulation |
denotes |
involved |
T19766 |
5181-5190 |
Positive_regulation |
denotes |
induction |
T19765 |
5181-5190 |
Positive_regulation |
denotes |
induction |
T19760 |
5194-5199 |
Protein |
denotes |
IL-17 |
T19761 |
5203-5210 |
Protein |
denotes |
RA PBMC |
T19769 |
5229-5233 |
Protein |
denotes |
AP-1 |
T19770 |
5389-5393 |
Protein |
denotes |
PI3K |
T19771 |
5420-5423 |
Protein |
denotes |
Akt |
T19775 |
5427-5438 |
Binding |
denotes |
association |
T19774 |
5427-5438 |
Binding |
denotes |
association |
T19772 |
5444-5449 |
Protein |
denotes |
NF-κB |
T19773 |
5551-5556 |
Protein |
denotes |
IL-17 |
T19776 |
5605-5609 |
Protein |
denotes |
PI3K |
T19777 |
5610-5613 |
Protein |
denotes |
Akt |
T19778 |
5628-5633 |
Protein |
denotes |
NF-κB |
T19781 |
5634-5644 |
Positive_regulation |
denotes |
activation |
T19789 |
5767-5775 |
Negative_regulation |
denotes |
blocking |
T19788 |
5767-5775 |
Negative_regulation |
denotes |
blocking |
T19787 |
5767-5775 |
Negative_regulation |
denotes |
blocking |
T19786 |
5767-5775 |
Negative_regulation |
denotes |
blocking |
T19779 |
5779-5784 |
Protein |
denotes |
NF-κB |
T19785 |
5785-5792 |
Binding |
denotes |
binding |
T19784 |
5785-5792 |
Binding |
denotes |
binding |
T19783 |
5785-5792 |
Binding |
denotes |
binding |
T19782 |
5785-5792 |
Binding |
denotes |
binding |
T19780 |
5809-5823 |
Protein |
denotes |
IL-17 promoter |
T19792 |
5904-5913 |
Positive_regulation |
denotes |
induction |
T19790 |
5917-5927 |
Protein |
denotes |
anti-IL-17 |
T19791 |
6003-6008 |
Protein |
denotes |
IL-17 |
R10483 |
T19626 |
T19630 |
themeOf |
IL-17,production |
R10484 |
T19627 |
T19631 |
themeOf |
IL-17,production |
R10485 |
T19630 |
T19632 |
themeOf |
production,stimulate |
R10486 |
T19636 |
T19637 |
themeOf |
IL-17,upregulation |
R10487 |
T19638 |
T19640 |
themeOf |
IL-17,produced |
R10488 |
T19642 |
T19644 |
themeOf |
type II collagen,recognizing |
R10489 |
T19644 |
T19645 |
themeOf |
recognizing,augmented |
R10490 |
T19646 |
T19649 |
themeOf |
IL-6,secrete |
R10491 |
T19647 |
T19650 |
themeOf |
IL-8,secrete |
R10492 |
T19648 |
T19651 |
themeOf |
tumor necrosis factor-stimulated gene 6,secrete |
R10493 |
T19652 |
T19653 |
themeOf |
IL-17,production |
R10494 |
T19653 |
T19654 |
themeOf |
production,stimulate |
R10495 |
T19655 |
T19661 |
themeOf |
IL-17,production |
R10496 |
T19656 |
T19662 |
themeOf |
RA PBMC,production |
R10497 |
T19657 |
T19663 |
themeOf |
T cell receptor,ligation |
R10498 |
T19658 |
T19664 |
themeOf |
TCR,ligation |
R10499 |
T19665 |
T19671 |
themeOf |
IL-15,ligation |
R10500 |
T19665 |
T19674 |
causeOf |
IL-15,increased |
R10501 |
T19665 |
T19675 |
causeOf |
IL-15,increased |
R10502 |
T19666 |
T19676 |
causeOf |
MCP-1,increased |
R10503 |
T19666 |
T19677 |
causeOf |
MCP-1,increased |
R10504 |
T19667 |
T19670 |
themeOf |
TCR,ligation |
R10505 |
T19667 |
T19671 |
themeOf |
TCR,ligation |
R10506 |
T19668 |
T19672 |
themeOf |
IL-17,production |
R10507 |
T19669 |
T19673 |
themeOf |
RA PBMC,production |
R10508 |
T19670 |
T19678 |
causeOf |
ligation,increased |
R10509 |
T19670 |
T19679 |
causeOf |
ligation,increased |
R10510 |
T19671 |
T19680 |
causeOf |
ligation,increased |
R10511 |
T19671 |
T19681 |
causeOf |
ligation,increased |
R10512 |
T19672 |
T19674 |
themeOf |
production,increased |
R10513 |
T19672 |
T19676 |
themeOf |
production,increased |
R10514 |
T19672 |
T19678 |
themeOf |
production,increased |
R10515 |
T19672 |
T19680 |
themeOf |
production,increased |
R10516 |
T19673 |
T19675 |
themeOf |
production,increased |
R10517 |
T19673 |
T19677 |
themeOf |
production,increased |
R10518 |
T19673 |
T19679 |
themeOf |
production,increased |
R10519 |
T19673 |
T19681 |
themeOf |
production,increased |
R10520 |
T19684 |
T19685 |
themeOf |
TCR,ligation |
R10521 |
T19686 |
T19690 |
causeOf |
IL-1,affect |
R10522 |
T19687 |
T19691 |
causeOf |
TNF-α,affect |
R10523 |
T19688 |
T19689 |
themeOf |
IL-17,production |
R10524 |
T19689 |
T19690 |
themeOf |
production,affect |
R10525 |
T19689 |
T19691 |
themeOf |
production,affect |
R10526 |
T19696 |
T19698 |
themeOf |
IL-17,induction |
R10527 |
T19697 |
T19699 |
themeOf |
RA PBMC,induction |
R10528 |
T19698 |
T19700 |
themeOf |
induction,increases |
R10529 |
T19699 |
T19701 |
themeOf |
induction,increases |
R10530 |
T19703 |
T19704 |
themeOf |
IL-17,production |
R10531 |
T19704 |
T19705 |
themeOf |
production,regulated |
R10532 |
T19707 |
T19708 |
themeOf |
RA PBMC,induction |
R10533 |
T19709 |
T19716 |
causeOf |
CD3,induced |
R10534 |
T19710 |
T19714 |
themeOf |
RA PBMC,production |
R10535 |
T19712 |
T19715 |
causeOf |
LY294002,hampered |
R10536 |
T19714 |
T19715 |
themeOf |
production,hampered |
R10537 |
T19714 |
T19716 |
themeOf |
production,induced |
R10538 |
T19718 |
T19719 |
themeOf |
p38 MAPK,inhibitor |
R10539 |
T19722 |
T19727 |
themeOf |
IκB kinase-β,activated |
R10540 |
T19723 |
T19728 |
themeOf |
p38,activated |
R10541 |
T19724 |
T19729 |
themeOf |
NF-κB,stimulate |
R10542 |
T19726 |
T19730 |
themeOf |
CREB,binding |
R10543 |
T19728 |
T19729 |
causeOf |
activated,stimulate |
R10544 |
T19731 |
T19735 |
themeOf |
p38 MAPK,activation |
R10545 |
T19732 |
T19737 |
themeOf |
NF-κB,binding |
R10546 |
T19734 |
T19739 |
themeOf |
PI3K,activation |
R10547 |
T19735 |
T19736 |
themeOf |
activation,affected |
R10548 |
T19737 |
T19738 |
themeOf |
binding,decreased |
R10549 |
T19742 |
T19743 |
themeOf |
IL-17,production |
R10550 |
T19745 |
T19746 |
themeOf |
Akt,activation |
R10551 |
T19746 |
T19747 |
themeOf |
activation,loss |
R10552 |
T19748 |
T19752 |
themeOf |
Akt,phosphorylated |
R10553 |
T19750 |
T19754 |
causeOf |
PI3K,involvement |
R10554 |
T19751 |
T19753 |
themeOf |
IL-17,induction |
R10555 |
T19753 |
T19754 |
themeOf |
induction,involvement |
R10556 |
T19755 |
T19762 |
themeOf |
NF-κB,activated |
R10557 |
T19755 |
T19763 |
themeOf |
NF-κB,activated |
R10558 |
T19755 |
T19764 |
themeOf |
NF-κB,activated |
R10559 |
T19756 |
T19762 |
causeOf |
anti-CD3,activated |
R10560 |
T19757 |
T19763 |
causeOf |
anti-CD28,activated |
R10561 |
T19758 |
T19764 |
causeOf |
IL-15,activated |
R10562 |
T19759 |
T19767 |
causeOf |
NF-κB,involved |
R10563 |
T19759 |
T19768 |
causeOf |
NF-κB,involved |
R10564 |
T19760 |
T19765 |
themeOf |
IL-17,induction |
R10565 |
T19761 |
T19766 |
themeOf |
RA PBMC,induction |
R10566 |
T19765 |
T19767 |
themeOf |
induction,involved |
R10567 |
T19766 |
T19768 |
themeOf |
induction,involved |
R10568 |
T19771 |
T19775 |
themeOf |
Akt,association |
R10569 |
T19772 |
T19774 |
themeOf |
NF-κB,association |
R10570 |
T19772 |
T19775 |
themeOf |
NF-κB,association |
R10571 |
T19777 |
T19784 |
themeOf |
Akt,binding |
R10572 |
T19778 |
T19781 |
themeOf |
NF-κB,activation |
R10573 |
T19779 |
T19782 |
themeOf |
NF-κB,binding |
R10574 |
T19779 |
T19784 |
themeOf |
NF-κB,binding |
R10575 |
T19779 |
T19785 |
themeOf |
NF-κB,binding |
R10576 |
T19780 |
T19783 |
themeOf |
IL-17 promoter,binding |
R10577 |
T19780 |
T19785 |
themeOf |
IL-17 promoter,binding |
R10578 |
T19782 |
T19786 |
themeOf |
binding,blocking |
R10579 |
T19783 |
T19787 |
themeOf |
binding,blocking |
R10580 |
T19784 |
T19788 |
themeOf |
binding,blocking |
R10581 |
T19785 |
T19789 |
themeOf |
binding,blocking |
R10582 |
T19790 |
T19792 |
themeOf |
anti-IL-17,induction |