| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T5649 |
0-4 |
Protein |
denotes |
WWOX |
| T5764 |
0-50 |
Binding |
denotes |
WWOX binds MEK in Jurkat T cells (Lin et al., 2011 |
| T5641 |
11-14 |
Entity |
denotes |
MEK |
| T5722 |
18-45 |
Entity |
denotes |
Jurkat T cells (Lin et al., |
| T5736 |
34-37 |
Entity |
denotes |
Lin |
| T5691 |
34-43 |
Entity |
denotes |
Lin et al |
| T5651 |
53-60 |
Entity |
denotes |
Phorbol |
| T5733 |
53-84 |
Entity |
denotes |
Phorbol myristate acetate (PMA) |
| T5687 |
53-84 |
Entity |
denotes |
Phorbol myristate acetate (PMA) |
| T5656 |
80-83 |
Entity |
denotes |
PMA |
| T5735 |
97-117 |
Entity |
denotes |
the MEK/WWOX complex |
| T5628 |
97-117 |
Entity |
denotes |
the MEK/WWOX complex |
| T5705 |
105-109 |
Protein |
denotes |
WWOX |
| T5683 |
130-134 |
Protein |
denotes |
WWOX |
| T5669 |
153-169 |
Entity |
denotes |
the mitochondria |
| T5716 |
199-202 |
Entity |
denotes |
MEK |
| T5707 |
220-225 |
Entity |
denotes |
lipid |
| T5763 |
232-258 |
Negative_regulation |
denotes |
Inhibition of MEK activity |
| T5673 |
246-249 |
Entity |
denotes |
MEK |
| T5696 |
269-280 |
Entity |
denotes |
TMZ-induced |
| T5761 |
344-376 |
Gene_expression |
denotes |
expression of WWOX in A549 cells |
| T5728 |
355-362 |
Protein |
denotes |
of WWOX |
| T5616 |
385-397 |
Protein |
denotes |
procaspase-3 |
| T5737 |
402-414 |
Protein |
denotes |
procaspase-9 |
| T5753 |
402-425 |
Positive_regulation |
denotes |
procaspase-9 activation |
| T5700 |
438-450 |
Entity |
denotes |
cytochrome C |
| T5699 |
466-482 |
Entity |
denotes |
the mitochondria |
| T5758 |
529-557 |
Phosphorylation |
denotes |
ectopic WWOX phosphorylation |
| T5668 |
537-541 |
Protein |
denotes |
WWOX |
| T5632 |
580-584 |
Entity |
denotes |
cell |
| T5660 |
687-694 |
Protein |
denotes |
of WWOX |
| T5631 |
710-740 |
Entity |
denotes |
the membrane/cytoskeleton area |
| T5760 |
745-778 |
Binding |
denotes |
binding with hyaluronidase Hyal-2 |
| T5658 |
753-778 |
Protein |
denotes |
with hyaluronidase Hyal-2 |
| T5698 |
758-771 |
Protein |
denotes |
hyaluronidase |
| T5627 |
802-815 |
Protein |
denotes |
Phospho-Ezrin |
| T5647 |
802-815 |
Protein |
denotes |
Phospho-Ezrin |
| T5719 |
836-865 |
Protein |
denotes |
Transforming growth factor β1 |
| T5757 |
836-883 |
Binding |
denotes |
Transforming growth factor β1 binds Hyal-2 as a |
| T5695 |
872-878 |
Protein |
denotes |
Hyal-2 |
| T5639 |
884-900 |
Protein |
denotes |
cognate receptor |
| T5769 |
911-1032 |
Gene_expression |
denotes |
the formation of the WWOX/Hyal-2/Smad4 complex to relocate to the nucleus for enhancing the SMAD-driven promoter activity |
| T5652 |
932-936 |
Protein |
denotes |
WWOX |
| T5684 |
932-949 |
Protein |
denotes |
WWOX/Hyal-2/Smad4 |
| T5644 |
932-949 |
Protein |
denotes |
WWOX/Hyal-2/Smad4 |
| T5648 |
937-943 |
Protein |
denotes |
Hyal-2 |
| T5714 |
973-984 |
Entity |
denotes |
the nucleus |
| T5745 |
989-1032 |
Positive_regulation |
denotes |
enhancing the SMAD-driven promoter activity |
| T5659 |
1015-1023 |
Entity |
denotes |
promoter |
| R3844 |
T5641 |
T5764 |
themeOf |
MEK,"WWOX binds MEK in Jurkat T cells (Lin et al., 2011" |
| R3847 |
T5649 |
T5764 |
themeOf |
WWOX,"WWOX binds MEK in Jurkat T cells (Lin et al., 2011" |
| R3852 |
T5658 |
T5760 |
themeOf |
with hyaluronidase Hyal-2,binding with hyaluronidase Hyal-2 |
| R3862 |
T5668 |
T5758 |
themeOf |
WWOX,ectopic WWOX phosphorylation |
| R3873 |
T5684 |
T5769 |
themeOf |
WWOX/Hyal-2/Smad4,the formation of the WWOX/Hyal-2/Smad4 complex to relocate to the nucleus for enhancing the SMAD-driven promoter activity |
| R3881 |
T5695 |
T5757 |
themeOf |
Hyal-2,Transforming growth factor β1 binds Hyal-2 as a |
| R3885 |
T5737 |
T5753 |
themeOf |
procaspase-9,procaspase-9 activation |
| R3889 |
T5719 |
T5757 |
themeOf |
Transforming growth factor β1,Transforming growth factor β1 binds Hyal-2 as a |
| R3892 |
T5728 |
T5761 |
themeOf |
of WWOX,expression of WWOX in A549 cells |
