PMC:3312845 / 28471-34035 JSONTXT 25 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function

Id Subject Object Predicate Lexical cue
T14368 60-65 Protein denotes TNF-α
T14402 60-75 Positive_regulation denotes TNF-α signaling
T14374 114-119 Protein denotes NF-κB
T14403 114-135 Phosphorylation denotes NF-κB phosphorylation
T14375 139-145 Entity denotes the PC
T14273 156-158 Entity denotes SE
T14335 222-232 Entity denotes neutrophil
T14258 374-397 Entity denotes the extracellular space
T14263 615-620 Protein denotes TNF-α
T14303 664-696 Entity denotes microglia in the PC following SE
T14315 677-696 Protein denotes the PC following SE
T14378 694-696 Protein denotes SE
T14276 698-701 Protein denotes TNF
T14278 698-722 Protein denotes TNF receptor expressions
T14376 749-781 Entity denotes astrocytes (TNFp55R and TNFp75R)
T14381 786-813 Entity denotes endothelial cells (TNFp75R)
T14337 805-812 Protein denotes TNFp75R
T14400 837-855 Positive_regulation denotes of TNF-α signaling
T14287 840-845 Protein denotes TNF-α
T14312 856-875 Entity denotes by sTNFp55 infusion
T14325 928-938 Entity denotes SE-induced
T14354 978-984 Protein denotes the PC
T14350 1015-1020 Protein denotes TNF-α
T14299 1080-1083 Entity denotes SE,
T14261 1106-1116 Entity denotes SE-induced
T14314 1158-1163 Protein denotes TNF-α
T14405 1158-1173 Positive_regulation denotes TNF-α signaling
T14301 1268-1284 Entity denotes sTNFp55 infusion
T14389 1314-1324 Entity denotes SE-induced
T14280 1364-1370 Protein denotes the PC
T14328 1409-1414 Protein denotes TNF-α
T14409 1409-1424 Positive_regulation denotes TNF-α signaling
T14327 1492-1495 Protein denotes p65
T14398 1492-1520 Phosphorylation denotes p65 phosphorylation of NF-κB
T14275 1512-1520 Protein denotes of NF-κB
T14290 1565-1568 Protein denotes p65
T14412 1565-1584 Phosphorylation denotes p65 phosphorylation
T14336 1602-1615 Entity denotes the cytoplasm
T14297 1619-1635 Entity denotes the nucleus [30]
T14292 1659-1669 Entity denotes p65-Thr435
T14361 1659-1669 Protein denotes p65-Thr435
T14386 1663-1669 Entity denotes Thr435
T14334 1703-1720 Entity denotes endothelial cells
T14342 1844-1852 Entity denotes antigen,
T14310 1856-1912 Protein denotes a protein expressed by endothelial cells of rat BBB [31]
T14410 1856-1912 Gene_expression denotes a protein expressed by endothelial cells of rat BBB [31]
T14266 1876-1912 Entity denotes by endothelial cells of rat BBB [31]
T14330 1974-2005 Entity denotes endothelial cells [5,7,8,30,32]
T14366 2195-2247 Entity denotes of intercellular junctions between endothelial cells
T14358 2230-2247 Entity denotes endothelial cells
T14370 2340-2356 Entity denotes endothelial cell
T14298 2477-2479 Entity denotes SE
T14329 2549-2566 Entity denotes sTNFp55R infusion
T14284 2550-2553 Protein denotes TNF
T14293 2589-2599 Entity denotes SE-induced
T14395 2640-2688 Phosphorylation denotes the phosphorylation of p65-Thr435 by TNF-α [39],
T14300 2660-2673 Protein denotes of p65-Thr435
T14371 2660-2673 Entity denotes of p65-Thr435
T14352 2674-2687 Protein denotes by TNF-α [39]
T14268 2716-2730 Protein denotes TNF-α-mediated
T14406 2716-2778 Regulation denotes TNF-α-mediated p65-Thr435 phosphorylation in endothelial cells
T14291 2731-2741 Protein denotes p65-Thr435
T14347 2731-2741 Entity denotes p65-Thr435
T14388 2761-2778 Entity denotes endothelial cells
T14365 2956-2998 Protein denotes dystrophin (an actin-binding protein [40])
T14295 2968-2997 Protein denotes an actin-binding protein [40]
T14279 3095-3116 Protein denotes down-regulated 12 hrs
T14408 3095-3116 Negative_regulation denotes down-regulated 12 hrs
T14355 3123-3125 Protein denotes SE
T14269 3334-3351 Entity denotes endothelial cells
T14379 3356-3379 Entity denotes perivascular astrocytes
T14346 3403-3406 Protein denotes p65
T14307 3407-3413 Entity denotes Ser276
T14321 3415-3418 Protein denotes p65
T14294 3419-3425 Entity denotes Ser311
T14391 3427-3430 Protein denotes p65
T14377 3431-3437 Entity denotes Ser529
T14383 3443-3453 Entity denotes p65-Ser536
T14356 3443-3453 Protein denotes p65-Ser536
T14397 3443-3509 Phosphorylation denotes p65-Ser536 phosphorylation was observed in astrocytes following SE
T14344 3486-3509 Entity denotes astrocytes following SE
T14364 3507-3509 Protein denotes SE
T14304 3524-3541 Entity denotes sTNFp55R infusion
T14349 3525-3528 Protein denotes TNF
T14267 3564-3574 Protein denotes p65-Ser276
T14384 3564-3574 Entity denotes p65-Ser276
T14351 3608-3618 Entity denotes astrocytes
T14309 3629-3631 Protein denotes SE
T14399 3662-3681 Positive_regulation denotes enhanced p65-Ser276
T14360 3662-3681 Protein denotes enhanced p65-Ser276
T14340 3662-3681 Entity denotes enhanced p65-Ser276
T14380 3686-3696 Protein denotes p65-Ser311
T14369 3686-3696 Entity denotes p65-Ser311
T14413 3686-3712 Phosphorylation denotes p65-Ser311 phosphorylation
T14296 3732-3737 Protein denotes TNF-α
T14353 3772-3789 Entity denotes sTNFp55R infusion
T14390 3773-3776 Protein denotes TNF
T14289 3808-3818 Entity denotes p65-Ser529
T14363 3808-3818 Protein denotes p65-Ser529
T14332 3823-3850 Entity denotes p65-Ser536 phosphorylations
T14373 3823-3850 Protein denotes p65-Ser536 phosphorylations
T14331 3856-3858 Entity denotes SE
T14359 3874-3884 Protein denotes p65-Ser529
T14345 3874-3884 Entity denotes p65-Ser529
T14302 3889-3899 Entity denotes p65-Ser536
T14382 3889-3899 Protein denotes p65-Ser536
T14318 3922-3927 Protein denotes TNF-α
T14324 3932-3943 Protein denotes IL-1β [41],
T14272 3962-3976 Protein denotes IL-1β-mediated
T14357 4035-4045 Entity denotes SE-induced
T14322 4106-4111 Protein denotes TNF-α
T14281 4116-4121 Protein denotes IL-1β
T14372 4129-4147 Entity denotes synergists to play
T14316 4168-4185 Entity denotes endothelial cells
T14306 4203-4213 Entity denotes astrocytes
T14323 4260-4270 Entity denotes Neutrophil
T14271 4353-4358 Protein denotes of SE
T14333 4376-4378 Entity denotes SE
T14311 4412-4414 Entity denotes SE
T14288 4458-4468 Protein denotes chemokines
T14313 4524-4529 Protein denotes MIP-2
T14264 4546-4566 Entity denotes efficient neutrophil
T14282 4570-4580 Entity denotes lymphocyte
T14411 4570-4617 Binding denotes lymphocyte recruitment to brain parenchyma [43]
T14262 4647-4657 Entity denotes neutrophil
T14404 4714-4756 Gene_expression denotes by P2X7 receptor-mediated MIP-2 expression
T14401 4714-4756 Regulation denotes by P2X7 receptor-mediated MIP-2 expression
T14317 4717-4721 Protein denotes P2X7
T14285 4722-4739 Protein denotes receptor-mediated
T14270 4740-4745 Protein denotes MIP-2
T14343 4761-4768 Protein denotes the PC,
T14394 4802-4820 Entity denotes agonist/antagonist
T14348 4802-4820 Entity denotes agonist/antagonist
T14341 4810-4820 Entity denotes antagonist
T14362 4825-4853 Protein denotes IL-1Ra (an IL-1β antagonist)
T14393 4825-4862 Entity denotes IL-1Ra (an IL-1β antagonist) infusion
T14319 4833-4852 Protein denotes an IL-1β antagonist
T14392 4880-4889 Entity denotes leukocyte
T14326 4927-4934 Entity denotes TNFp55R
T14367 4927-4934 Protein denotes TNFp55R
T14260 4935-4943 Entity denotes infusion
T14283 4966-4976 Entity denotes neutrophil
T14274 4993-4999 Protein denotes the PC
T14407 5003-5067 Negative_regulation denotes reducing vasogenic edema formation in a MIP-2-independent manner
T14339 5043-5060 Protein denotes MIP-2-independent
T14338 5175-5183 Protein denotes by TNF-α
T14286 5195-5205 Entity denotes neutrophil
T14387 5273-5280 Protein denotes the PC,
T14308 5364-5380 Entity denotes endothelial cell
T14320 5394-5408 Protein denotes TNF-α mediated
T14414 5394-5408 Regulation denotes TNF-α mediated
T14265 5394-5442 Protein denotes TNF-α mediated p65-Thr 435 NF-κB phosphorylation
T14259 5394-5442 Entity denotes TNF-α mediated p65-Thr 435 NF-κB phosphorylation
T14396 5394-5442 Phosphorylation denotes TNF-α mediated p65-Thr 435 NF-κB phosphorylation
T14305 5421-5426 Protein denotes NF-κB
T14385 5462-5464 Entity denotes SE
T14277 5511-5521 Entity denotes neutrophil
R11186 T14259 T14305 partOf TNF-α mediated p65-Thr 435 NF-κB phosphorylation,NF-κB
R11187 T14259 T14396 siteOf TNF-α mediated p65-Thr 435 NF-κB phosphorylation,TNF-α mediated p65-Thr 435 NF-κB phosphorylation
R11189 T14268 T14406 causeOf TNF-α-mediated,TNF-α-mediated p65-Thr435 phosphorylation in endothelial cells
R11192 T14270 T14404 themeOf MIP-2,by P2X7 receptor-mediated MIP-2 expression
R11195 T14275 T14398 themeOf of NF-κB,p65 phosphorylation of NF-κB
R11196 T14279 T14408 themeOf down-regulated 12 hrs,down-regulated 12 hrs
R11197 T14285 T14401 causeOf receptor-mediated,by P2X7 receptor-mediated MIP-2 expression
R11198 T14287 T14400 causeOf TNF-α,of TNF-α signaling
R11199 T14290 T14412 themeOf p65,p65 phosphorylation
R11200 T14380 T14413 themeOf p65-Ser311,p65-Ser311 phosphorylation
R11201 T14383 T14356 partOf p65-Ser536,p65-Ser536
R11202 T14383 T14397 siteOf p65-Ser536,p65-Ser536 phosphorylation was observed in astrocytes following SE
R11203 T14300 T14395 themeOf of p65-Thr435,"the phosphorylation of p65-Thr435 by TNF-α [39],"
R11204 T14305 T14396 themeOf NF-κB,TNF-α mediated p65-Thr 435 NF-κB phosphorylation
R11205 T14310 T14410 themeOf a protein expressed by endothelial cells of rat BBB [31],a protein expressed by endothelial cells of rat BBB [31]
R11206 T14404 T14401 themeOf by P2X7 receptor-mediated MIP-2 expression,by P2X7 receptor-mediated MIP-2 expression
R11207 T14314 T14405 causeOf TNF-α,TNF-α signaling
R11208 T14320 T14396 causeOf TNF-α mediated,TNF-α mediated p65-Thr 435 NF-κB phosphorylation
R11209 T14320 T14414 themeOf TNF-α mediated,TNF-α mediated
R11210 T14327 T14398 causeOf p65,p65 phosphorylation of NF-κB
R11211 T14328 T14409 causeOf TNF-α,TNF-α signaling
R11212 T14352 T14395 causeOf by TNF-α [39],"the phosphorylation of p65-Thr435 by TNF-α [39],"
R11213 T14356 T14397 themeOf p65-Ser536,p65-Ser536 phosphorylation was observed in astrocytes following SE
R11214 T14360 T14399 themeOf enhanced p65-Ser276,enhanced p65-Ser276
R11215 T14368 T14402 causeOf TNF-α,TNF-α signaling
R11216 T14369 T14380 partOf p65-Ser311,p65-Ser311
R11217 T14369 T14413 siteOf p65-Ser311,p65-Ser311 phosphorylation
R11218 T14371 T14300 partOf of p65-Thr435,of p65-Thr435
R11219 T14371 T14395 siteOf of p65-Thr435,"the phosphorylation of p65-Thr435 by TNF-α [39],"
R11220 T14374 T14403 themeOf NF-κB,NF-κB phosphorylation