Id |
Subject |
Object |
Predicate |
Lexical cue |
T9306 |
0-5 |
Protein |
denotes |
NF-κB |
T9342 |
0-21 |
Phosphorylation |
denotes |
NF-κB phosphorylation |
T9303 |
50-55 |
Protein |
denotes |
TNF-α |
T9339 |
91-115 |
Phosphorylation |
denotes |
phosphorylation of NF-κB |
T9331 |
107-115 |
Protein |
denotes |
of NF-κB |
T9312 |
128-142 |
Protein |
denotes |
TNF-α-mediated |
T9305 |
128-166 |
Entity |
denotes |
TNF-α-mediated signaling following SE, |
T9335 |
215-244 |
Entity |
denotes |
five phospho-NF-κB antibodies |
T9300 |
228-233 |
Protein |
denotes |
NF-κB |
T9322 |
302-304 |
Protein |
denotes |
SE |
T9333 |
316-326 |
Entity |
denotes |
the saline |
T9301 |
348-358 |
Entity |
denotes |
p65-Ser276 |
T9292 |
348-358 |
Protein |
denotes |
p65-Ser276 |
T9315 |
360-370 |
Protein |
denotes |
p65-Ser311 |
T9308 |
360-370 |
Entity |
denotes |
p65-Ser311 |
T9320 |
372-382 |
Entity |
denotes |
p65-Ser529 |
T9295 |
372-382 |
Protein |
denotes |
p65-Ser529 |
T9327 |
388-398 |
Protein |
denotes |
p65-Ser536 |
T9314 |
388-398 |
Entity |
denotes |
p65-Ser536 |
T9340 |
388-414 |
Phosphorylation |
denotes |
p65-Ser536 phosphorylation |
T9325 |
418-428 |
Entity |
denotes |
astrocytes |
T9330 |
434-451 |
Entity |
denotes |
endothelial cells |
T9334 |
454-471 |
Entity |
denotes |
sTNFp55R infusion |
T9302 |
455-458 |
Protein |
denotes |
TNF |
T9309 |
492-502 |
Entity |
denotes |
p65-Ser276 |
T9299 |
492-502 |
Protein |
denotes |
p65-Ser276 |
T9307 |
507-517 |
Protein |
denotes |
p65-Ser311 |
T9296 |
507-517 |
Entity |
denotes |
p65-Ser311 |
T9338 |
507-533 |
Phosphorylation |
denotes |
p65-Ser311 phosphorylation |
T9326 |
535-536 |
Entity |
denotes |
p |
T9332 |
586-596 |
Protein |
denotes |
p65-Ser529 |
T9311 |
586-596 |
Entity |
denotes |
p65-Ser529 |
T9323 |
600-610 |
Entity |
denotes |
p65-Ser536 |
T9313 |
600-610 |
Protein |
denotes |
p65-Ser536 |
T9341 |
600-626 |
Phosphorylation |
denotes |
p65-Ser536 phosphorylation |
T9336 |
647-721 |
Positive_regulation |
denotes |
In contrast, p65-Thr435 phosphorylation was increased in endothelial cells |
T9321 |
660-670 |
Entity |
denotes |
p65-Thr435 |
T9298 |
660-670 |
Protein |
denotes |
p65-Thr435 |
T9337 |
660-686 |
Phosphorylation |
denotes |
p65-Thr435 phosphorylation |
T9293 |
704-721 |
Entity |
denotes |
endothelial cells |
T9324 |
727-737 |
Entity |
denotes |
astrocytes |
T9297 |
746-778 |
Protein |
denotes |
the PC of saline-infused animals |
T9317 |
791-805 |
Protein |
denotes |
SE (Figure 5A) |
T9329 |
821-824 |
Protein |
denotes |
TNF |
T9316 |
821-837 |
Entity |
denotes |
TNFp55R infusion |
T9294 |
861-871 |
Entity |
denotes |
SE-induced |
T9318 |
861-882 |
Entity |
denotes |
SE-induced p65-Thr435 |
T9291 |
861-882 |
Protein |
denotes |
SE-induced p65-Thr435 |
T9319 |
902-920 |
Entity |
denotes |
endothelial cells, |
T9328 |
930-939 |
Entity |
denotes |
to saline |
T9304 |
940-948 |
Entity |
denotes |
infusion |
T9310 |
950-951 |
Entity |
denotes |
p |
T15416 |
989-1009 |
Entity |
denotes |
of sTNFp55R infusion |
T15417 |
993-996 |
Protein |
denotes |
TNF |
T15434 |
1010-1048 |
Phosphorylation |
denotes |
on NF-κB phosphorylation in astrocytes |
T15423 |
1013-1018 |
Protein |
denotes |
NF-κB |
T15424 |
1038-1048 |
Entity |
denotes |
astrocytes |
T15430 |
1061-1063 |
Entity |
denotes |
SE |
T15413 |
1079-1081 |
Protein |
denotes |
SE |
T15431 |
1135-1145 |
Entity |
denotes |
astrocytes |
T15411 |
1151-1161 |
Entity |
denotes |
p65-Ser276 |
T15402 |
1151-1161 |
Protein |
denotes |
p65-Ser276 |
T15404 |
1167-1181 |
Entity |
denotes |
p65-Ser311 (C) |
T15401 |
1167-1181 |
Protein |
denotes |
p65-Ser311 (C) |
T15419 |
1183-1197 |
Entity |
denotes |
p65-Ser529 (E) |
T15406 |
1183-1197 |
Protein |
denotes |
p65-Ser529 (E) |
T15426 |
1203-1217 |
Entity |
denotes |
p65-Ser536 (G) |
T15421 |
1203-1217 |
Protein |
denotes |
p65-Ser536 (G) |
T15435 |
1203-1233 |
Phosphorylation |
denotes |
p65-Ser536 (G) phosphorylation |
T15420 |
1244-1252 |
Protein |
denotes |
sTNFp55R |
T15415 |
1244-1252 |
Entity |
denotes |
sTNFp55R |
T15425 |
1253-1277 |
Entity |
denotes |
infusion (B, D, F and H) |
T15407 |
1275-1276 |
Entity |
denotes |
H |
T15428 |
1298-1312 |
Protein |
denotes |
p65-Ser276 (B) |
T15418 |
1298-1312 |
Entity |
denotes |
p65-Ser276 (B) |
T15427 |
1302-1308 |
Entity |
denotes |
Ser276 |
T15410 |
1317-1331 |
Entity |
denotes |
p65-Ser311 (D) |
T15408 |
1317-1331 |
Protein |
denotes |
p65-Ser311 (D) |
T15409 |
1321-1327 |
Entity |
denotes |
Ser311 |
T15422 |
1374-1388 |
Entity |
denotes |
p65-Ser529 (F) |
T15403 |
1374-1388 |
Protein |
denotes |
p65-Ser529 (F) |
T15429 |
1386-1387 |
Entity |
denotes |
F |
T15432 |
1393-1407 |
Entity |
denotes |
p65-Ser536 (H) |
T15414 |
1393-1407 |
Protein |
denotes |
p65-Ser536 (H) |
T15433 |
1393-1423 |
Phosphorylation |
denotes |
p65-Ser536 (H) phosphorylation |
T15412 |
1405-1406 |
Entity |
denotes |
H |
T15405 |
1434-1447 |
Protein |
denotes |
Bar = 12.5 μm |
T15685 |
1495-1515 |
Entity |
denotes |
of sTNFp55R infusion |
T15680 |
1499-1502 |
Protein |
denotes |
TNF |
T15682 |
1519-1524 |
Protein |
denotes |
NF-κB |
T15693 |
1519-1540 |
Phosphorylation |
denotes |
NF-κB phosphorylation |
T15694 |
1590-1644 |
Phosphorylation |
denotes |
of NF-κB phosphorylation 12 hr after SE (mean ± S.E.M) |
T15689 |
1593-1598 |
Protein |
denotes |
NF-κB |
T15684 |
1627-1644 |
Entity |
denotes |
SE (mean ± S.E.M) |
T15686 |
1675-1681 |
Entity |
denotes |
saline |
T15690 |
1714-1771 |
Protein |
denotes |
Quantitative analysis of SMI-71 expression 1 day after SE |
T15687 |
1817-1823 |
Entity |
denotes |
saline |
T15683 |
1891-1901 |
Entity |
denotes |
p65-Thr435 |
T15681 |
1891-1901 |
Protein |
denotes |
p65-Thr435 |
T15692 |
1891-1917 |
Phosphorylation |
denotes |
p65-Thr435 phosphorylation |
T15688 |
1932-1951 |
Protein |
denotes |
the PC following SE |
T15691 |
1949-1951 |
Entity |
denotes |
SE |
T16211 |
1963-2041 |
Protein |
denotes |
Effect of sTNFp55R infusion on p65-Thr435 phosphorylation in endothelial cells |
T16204 |
1963-2041 |
Entity |
denotes |
Effect of sTNFp55R infusion on p65-Thr435 phosphorylation in endothelial cells |
T16198 |
1963-2041 |
Protein |
denotes |
Effect of sTNFp55R infusion on p65-Thr435 phosphorylation in endothelial cells |
T16208 |
1998-2004 |
Entity |
denotes |
Thr435 |
T16181 |
2024-2041 |
Entity |
denotes |
endothelial cells |
T16178 |
2052-2054 |
Protein |
denotes |
SE |
T16218 |
2073-2102 |
Phosphorylation |
denotes |
of p65-Thr435 phosphorylation |
T16189 |
2076-2086 |
Protein |
denotes |
p65-Thr435 |
T16182 |
2076-2086 |
Entity |
denotes |
p65-Thr435 |
T16193 |
2103-2123 |
Entity |
denotes |
by sTNFp55R infusion |
T16200 |
2107-2110 |
Protein |
denotes |
TNF |
T16191 |
2136-2138 |
Entity |
denotes |
SE |
T16212 |
2140-2150 |
Entity |
denotes |
p65-Thr435 |
T16197 |
2140-2150 |
Protein |
denotes |
p65-Thr435 |
T16217 |
2140-2208 |
Phosphorylation |
denotes |
p65-Thr435 phosphorylation is rarely observed in astrocytes (arrows) |
T16180 |
2189-2208 |
Entity |
denotes |
astrocytes (arrows) |
T16215 |
2214-2270 |
Phosphorylation |
denotes |
Endothelial p65-Thr435 phosphorylation in non-SE animals |
T16206 |
2214-2270 |
Protein |
denotes |
Endothelial p65-Thr435 phosphorylation in non-SE animals |
T16207 |
2230-2236 |
Entity |
denotes |
Thr435 |
T16205 |
2273-2276 |
Entity |
denotes |
D-E |
T16219 |
2278-2357 |
Phosphorylation |
denotes |
Endothelial p65-Thr435 phosphorylation in saline-infused animals 1 day after SE |
T16202 |
2290-2300 |
Protein |
denotes |
p65-Thr435 |
T16184 |
2290-2300 |
Entity |
denotes |
p65-Thr435 |
T16183 |
2320-2357 |
Protein |
denotes |
saline-infused animals 1 day after SE |
T16199 |
2359-2369 |
Protein |
denotes |
p65-Thr435 |
T16196 |
2359-2369 |
Entity |
denotes |
p65-Thr435 |
T16216 |
2359-2385 |
Phosphorylation |
denotes |
p65-Thr435 phosphorylation |
T16213 |
2359-2397 |
Positive_regulation |
denotes |
p65-Thr435 phosphorylation is enhanced |
T16220 |
2399-2479 |
Negative_regulation |
denotes |
while SMI-71 expression is reduced in GLUT-1-positive endothelial cells (arrows) |
T16190 |
2437-2443 |
Protein |
denotes |
GLUT-1 |
T16210 |
2444-2470 |
Entity |
denotes |
positive endothelial cells |
T16214 |
2487-2567 |
Phosphorylation |
denotes |
Endothelial p65-Thr435 phosphorylation in sTNFp55R-infused animal 1 day after SE |
T16201 |
2499-2509 |
Entity |
denotes |
p65-Thr435 |
T16194 |
2499-2509 |
Protein |
denotes |
p65-Thr435 |
T16195 |
2529-2567 |
Entity |
denotes |
sTNFp55R-infused animal 1 day after SE |
T16188 |
2570-2577 |
Protein |
denotes |
TNFp55R |
T16185 |
2570-2577 |
Entity |
denotes |
TNFp55R |
T16192 |
2578-2586 |
Entity |
denotes |
infusion |
T16209 |
2607-2617 |
Protein |
denotes |
p65-Thr435 |
T16179 |
2607-2617 |
Entity |
denotes |
p65-Thr435 |
T16186 |
2653-2659 |
Protein |
denotes |
GLUT-1 |
T16203 |
2660-2686 |
Entity |
denotes |
positive endothelial cells |
T16187 |
2723-2726 |
Entity |
denotes |
E-G |
R11906 |
T15414 |
T15433 |
themeOf |
p65-Ser536 (H),p65-Ser536 (H) phosphorylation |
R11907 |
T15421 |
T15435 |
themeOf |
p65-Ser536 (G),p65-Ser536 (G) phosphorylation |
R11908 |
T15423 |
T15434 |
themeOf |
NF-κB,on NF-κB phosphorylation in astrocytes |
R11909 |
T15426 |
T15421 |
partOf |
p65-Ser536 (G),p65-Ser536 (G) |
R11910 |
T15426 |
T15435 |
siteOf |
p65-Ser536 (G),p65-Ser536 (G) phosphorylation |
R11911 |
T15432 |
T15414 |
partOf |
p65-Ser536 (H),p65-Ser536 (H) |
R11912 |
T15432 |
T15433 |
siteOf |
p65-Ser536 (H),p65-Ser536 (H) phosphorylation |
R12099 |
T15681 |
T15692 |
themeOf |
p65-Thr435,p65-Thr435 phosphorylation |
R12100 |
T15682 |
T15693 |
themeOf |
NF-κB,NF-κB phosphorylation |
R12101 |
T15683 |
T15681 |
partOf |
p65-Thr435,p65-Thr435 |
R12102 |
T15683 |
T15692 |
siteOf |
p65-Thr435,p65-Thr435 phosphorylation |
R12103 |
T15689 |
T15694 |
themeOf |
NF-κB,of NF-κB phosphorylation 12 hr after SE (mean ± S.E.M) |
R12364 |
T16182 |
T16189 |
partOf |
p65-Thr435,p65-Thr435 |
R12365 |
T16182 |
T16218 |
siteOf |
p65-Thr435,of p65-Thr435 phosphorylation |
R12366 |
T16184 |
T16202 |
partOf |
p65-Thr435,p65-Thr435 |
R12367 |
T16184 |
T16219 |
siteOf |
p65-Thr435,Endothelial p65-Thr435 phosphorylation in saline-infused animals 1 day after SE |
R12368 |
T16189 |
T16218 |
themeOf |
p65-Thr435,of p65-Thr435 phosphorylation |
R12369 |
T16194 |
T16214 |
themeOf |
p65-Thr435,Endothelial p65-Thr435 phosphorylation in sTNFp55R-infused animal 1 day after SE |
R12370 |
T16196 |
T16199 |
partOf |
p65-Thr435,p65-Thr435 |
R12371 |
T16196 |
T16216 |
siteOf |
p65-Thr435,p65-Thr435 phosphorylation |
R12372 |
T16197 |
T16217 |
themeOf |
p65-Thr435,p65-Thr435 phosphorylation is rarely observed in astrocytes (arrows) |
R12373 |
T16199 |
T16216 |
themeOf |
p65-Thr435,p65-Thr435 phosphorylation |
R12374 |
T16201 |
T16194 |
partOf |
p65-Thr435,p65-Thr435 |
R12375 |
T16201 |
T16214 |
siteOf |
p65-Thr435,Endothelial p65-Thr435 phosphorylation in sTNFp55R-infused animal 1 day after SE |
R12376 |
T16202 |
T16219 |
themeOf |
p65-Thr435,Endothelial p65-Thr435 phosphorylation in saline-infused animals 1 day after SE |
R12377 |
T16206 |
T16215 |
themeOf |
Endothelial p65-Thr435 phosphorylation in non-SE animals,Endothelial p65-Thr435 phosphorylation in non-SE animals |
R12378 |
T16207 |
T16206 |
partOf |
Thr435,Endothelial p65-Thr435 phosphorylation in non-SE animals |
R12379 |
T16207 |
T16215 |
siteOf |
Thr435,Endothelial p65-Thr435 phosphorylation in non-SE animals |
R12380 |
T16212 |
T16197 |
partOf |
p65-Thr435,p65-Thr435 |
R12381 |
T16212 |
T16217 |
siteOf |
p65-Thr435,p65-Thr435 phosphorylation is rarely observed in astrocytes (arrows) |
R12382 |
T16216 |
T16213 |
themeOf |
p65-Thr435 phosphorylation,p65-Thr435 phosphorylation is enhanced |
R7597 |
T9296 |
T9307 |
partOf |
p65-Ser311,p65-Ser311 |
R7598 |
T9296 |
T9338 |
siteOf |
p65-Ser311,p65-Ser311 phosphorylation |
R7599 |
T9298 |
T9337 |
themeOf |
p65-Thr435,p65-Thr435 phosphorylation |
R7600 |
T9306 |
T9342 |
themeOf |
NF-κB,NF-κB phosphorylation |
R7601 |
T9307 |
T9338 |
themeOf |
p65-Ser311,p65-Ser311 phosphorylation |
R7602 |
T9313 |
T9341 |
themeOf |
p65-Ser536,p65-Ser536 phosphorylation |
R7603 |
T9314 |
T9327 |
partOf |
p65-Ser536,p65-Ser536 |
R7604 |
T9314 |
T9340 |
siteOf |
p65-Ser536,p65-Ser536 phosphorylation |
R7605 |
T9321 |
T9298 |
partOf |
p65-Thr435,p65-Thr435 |
R7606 |
T9321 |
T9337 |
siteOf |
p65-Thr435,p65-Thr435 phosphorylation |
R7607 |
T9323 |
T9313 |
partOf |
p65-Ser536,p65-Ser536 |
R7608 |
T9323 |
T9341 |
siteOf |
p65-Ser536,p65-Ser536 phosphorylation |
R7609 |
T9327 |
T9340 |
themeOf |
p65-Ser536,p65-Ser536 phosphorylation |
R7610 |
T9331 |
T9339 |
themeOf |
of NF-κB,phosphorylation of NF-κB |
R7611 |
T9337 |
T9336 |
themeOf |
p65-Thr435 phosphorylation,"In contrast, p65-Thr435 phosphorylation was increased in endothelial cells" |