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PMC:3359311 / 15230-16298 JSONTXT 13 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T5326 0-10 JJ denotes Bay11-7082
T5327 11-19 NNS denotes inhibits
T5328 20-29 JJ denotes pro-IL-1β
T5329 30-40 NN denotes production
T5330 41-43 IN denotes in
T5331 44-52 NN denotes response
T5332 53-55 TO denotes to
T5333 56-58 NNP denotes P.
T5334 59-69 NN denotes aeruginosa
T5335 71-73 IN denotes In
T5336 74-82 NN denotes addition
T5337 83-85 TO denotes to
T5338 86-96 NN denotes inhibition
T5339 97-99 IN denotes of
T5340 100-105 JJ denotes NF-κB
T5341 106-114 NN denotes activity
T5342 114-115 , denotes ,
T5343 116-126 NN denotes Bay11-7082
T5344 127-130 MD denotes can
T5345 131-135 RB denotes also
T5346 136-144 RB denotes directly
T5347 145-152 VB denotes inhibit
T5348 153-156 DT denotes the
T5349 157-162 NNP denotes NLRP3
T5350 163-175 JJ denotes inflammasome
T5351 176-177 NNP denotes [
T5352 177-179 CD denotes 38
T5353 179-180 NNP denotes ]
T5354 180-181 . denotes .
T5355 182-184 TO denotes To
T5356 185-193 VB denotes validate
T5357 194-197 PRP$ denotes its
T5358 198-201 NN denotes use
T5359 202-204 IN denotes in
T5360 205-209 DT denotes this
T5361 210-215 NN denotes study
T5362 216-218 IN denotes as
T5363 219-221 DT denotes an
T5364 222-227 JJ denotes NF-κB
T5365 228-237 NN denotes inhibitor
T5366 237-238 , denotes ,
T5367 239-246 JJ denotes western
T5368 247-252 NNS denotes blots
T5369 253-256 IN denotes for
T5370 257-266 NN denotes pro-IL-1β
T5371 267-271 VBD denotes were
T5372 272-281 VBN denotes performed
T5373 282-291 IN denotes alongside
T5374 292-302 NN denotes inhibition
T5375 303-305 IN denotes of
T5376 306-310 NNP denotes CFTR
T5377 311-319 NN denotes activity
T5378 320-322 IN denotes by
T5379 323-333 NNP denotes CFTRinh172
T5380 334-336 IN denotes in
T5381 337-345 NN denotes response
T5382 346-348 TO denotes to
T5383 349-353 CD denotes PAO1
T5384 354-356 IN denotes at
T5385 357-358 CD denotes 4
T5386 359-364 NNS denotes hours
T5387 365-370 IN denotes after
T5388 371-382 NN denotes stimulation
T5389 383-384 -LRB- denotes (
T5390 384-388 NNP denotes Fig.
T5391 389-391 CD denotes 7a
T5392 391-392 -RRB- denotes )
T5393 392-393 . denotes .
T5394 394-397 PRP$ denotes Our
T5395 398-405 NNS denotes results
T5396 406-414 VBP denotes indicate
T5397 415-419 IN denotes that
T5398 420-430 JJ denotes Bay11-7082
T5399 431-439 VBZ denotes prevents
T5400 440-450 NN denotes production
T5401 451-453 IN denotes of
T5402 454-463 JJ denotes pro-IL-1β
T5403 464-471 IN denotes whereas
T5404 472-482 NNP denotes CFTRinh172
T5405 483-487 VBZ denotes does
T5406 488-491 RB denotes not
T5407 492-496 VB denotes seem
T5408 497-499 TO denotes to
T5409 500-506 VB denotes affect
T5410 507-509 PRP denotes it
T5411 509-510 . denotes .
T5412 511-515 DT denotes This
T5413 516-519 VBD denotes was
T5414 520-527 JJ denotes further
T5415 528-540 VBN denotes corroborated
T5416 541-543 IN denotes by
T5417 544-547 DT denotes the
T5418 548-555 NN denotes ability
T5419 556-566 NN denotes Bay11-7082
T5420 567-569 TO denotes to
T5421 570-577 VB denotes inhibit
T5422 578-582 NNP denotes IκBα
T5423 583-594 NN denotes degradation
T5424 595-597 IN denotes at
T5425 598-601 CD denotes 0.5
T5426 601-602 , denotes ,
T5427 603-604 CD denotes 1
T5428 604-605 , denotes ,
T5429 606-609 CC denotes and
T5430 610-613 CD denotes 1.5
T5431 614-619 NNS denotes hours
T5432 620-624 NN denotes post
T5433 625-629 CD denotes PAO1
T5434 630-641 NN denotes stimulation
T5435 642-643 -LRB- denotes (
T5436 643-647 NNP denotes Fig.
T5437 648-650 CD denotes 7b
T5438 650-651 -RRB- denotes )
T5439 651-652 . denotes .
T14573 697-707 JJ denotes Bay11-7082
T14574 708-716 NNS denotes inhibits
T14575 717-726 JJ denotes pro-IL-1β
T14576 727-737 NN denotes production
T14577 738-740 IN denotes in
T14578 741-749 NN denotes response
T14579 750-752 TO denotes to
T14580 753-755 NNP denotes P.
T14581 756-766 NN denotes aeruginosa
T14582 766-767 . denotes .
T14583 768-786 JJ denotes PMA-differentiated
T14584 787-792 NN denotes THP-1
T14585 793-798 NNS denotes cells
T14586 799-803 VBD denotes were
T14587 804-811 VBN denotes treated
T14588 812-816 IN denotes with
T14589 817-819 CD denotes 10
T14590 820-822 NNP denotes µM
T14591 823-833 NNP denotes CFTRinh172
T14592 834-836 CC denotes or
T14593 837-839 CD denotes 20
T14594 840-842 NNP denotes µM
T14595 843-853 NNP denotes Bay11-7082
T14596 854-857 CC denotes and
T14597 858-867 VBN denotes harvested
T14598 868-873 IN denotes after
T14599 874-875 -LRB- denotes (
T14600 875-876 NN denotes A
T14601 876-877 -RRB- denotes )
T14602 878-879 CD denotes 4
T14603 880-885 NNS denotes hours
T14604 886-887 -LRB- denotes (
T14605 887-888 FW denotes n
T14606 889-890 SYM denotes =
T14607 891-892 LS denotes 3
T14608 892-893 -RRB- denotes )
T14609 894-896 CC denotes or
T14610 897-898 -LRB- denotes (
T14611 898-899 NNP denotes B
T14612 899-900 -RRB- denotes )
T14613 901-904 CD denotes 0.5
T14614 904-905 , denotes ,
T14615 906-907 CD denotes 1
T14616 907-908 , denotes ,
T14617 909-912 CC denotes and
T14618 913-916 CD denotes 1.5
T14619 917-922 NNS denotes hours
T14620 923-924 -LRB- denotes (
T14621 924-925 FW denotes n
T14622 926-927 SYM denotes =
T14623 928-929 LS denotes 3
T14624 929-930 -RRB- denotes )
T14625 931-942 NN denotes stimulation
T14626 943-947 IN denotes with
T14627 948-952 NNP denotes PAO1
T14628 952-953 . denotes .
T14629 954-957 CD denotes One
T14630 958-972 NN denotes representative
T14631 973-977 NN denotes blot
T14632 978-980 VBZ denotes is
T14633 981-986 VBN denotes shown
T14634 987-991 IN denotes with
T14635 992-993 DT denotes a
T14636 994-999 NN denotes graph
T14637 1000-1002 IN denotes of
T14638 1003-1006 DT denotes the
T14639 1007-1015 VBN denotes averaged
T14640 1016-1028 NN denotes fluorescence
T14641 1029-1038 NN denotes intensity
T14642 1039-1045 NNS denotes values
T14643 1046-1050 IN denotes over
T14644 1051-1052 CD denotes 3
T14645 1053-1064 NNS denotes experiments
T14646 1064-1065 . denotes .
R12946 T14573 T14574 amod Bay11-7082,inhibits
R12947 T14574 T14574 ROOT inhibits,inhibits
R12948 T14575 T14576 compound pro-IL-1β,production
R12949 T14576 T14574 dobj production,inhibits
R12950 T14577 T14574 prep in,inhibits
R12951 T14578 T14577 pobj response,in
R12952 T14579 T14578 prep to,response
R12953 T14580 T14581 compound P.,aeruginosa
R12954 T14581 T14579 pobj aeruginosa,to
R12955 T14582 T14574 punct .,inhibits
R12956 T14583 T14585 amod PMA-differentiated,cells
R12957 T14584 T14585 compound THP-1,cells
R12958 T14585 T14587 nsubjpass cells,treated
R12959 T14586 T14587 auxpass were,treated
R12960 T14587 T14587 ROOT treated,treated
R12961 T14588 T14587 prep with,treated
R12962 T14589 T14591 nummod 10,CFTRinh172
R12963 T14590 T14591 compound µM,CFTRinh172
R12964 T14591 T14588 pobj CFTRinh172,with
R12965 T14592 T14591 cc or,CFTRinh172
R12966 T14593 T14595 nummod 20,Bay11-7082
R12967 T14594 T14595 compound µM,Bay11-7082
R12968 T14595 T14591 conj Bay11-7082,CFTRinh172
R12969 T14596 T14587 cc and,treated
R12970 T14597 T14587 conj harvested,treated
R12971 T14598 T14597 prep after,harvested
R12972 T14599 T14600 punct (,A
R12973 T14600 T14598 pobj A,after
R12974 T14601 T14600 punct ),A
R12975 T14602 T14603 nummod 4,hours
R12976 T14603 T14605 npadvmod hours,n
R12977 T14604 T14603 punct (,hours
R12978 T14605 T14597 advmod n,harvested
R12979 T14606 T14607 punct =,3
R12980 T14607 T14605 pobj 3,n
R12981 T14608 T14605 punct ),n
R12982 T14609 T14597 cc or,harvested
R12983 T14610 T14611 punct (,B
R12984 T14611 T14597 conj B,harvested
R12985 T14612 T14611 punct ),B
R12986 T14613 T14611 nummod 0.5,B
R12987 T14614 T14611 punct ",",B
R12988 T14615 T14611 nummod 1,B
R12989 T14616 T14611 punct ",",B
R12990 T14617 T14611 cc and,B
R12991 T14618 T14619 nummod 1.5,hours
R12992 T14619 T14621 npadvmod hours,n
R12993 T14620 T14619 punct (,hours
R12994 T14621 T14611 conj n,B
R12995 T14622 T14623 punct =,3
R12996 T14623 T14625 meta 3,stimulation
R12997 T14624 T14623 punct ),3
R12998 T14625 T14611 appos stimulation,B
R12999 T14626 T14625 prep with,stimulation
R13000 T14627 T14626 pobj PAO1,with
R13001 T14628 T14587 punct .,treated
R13002 T14629 T14631 nummod One,blot
R13003 T14630 T14631 compound representative,blot
R13004 T14631 T14633 nsubjpass blot,shown
R13005 T14632 T14633 auxpass is,shown
R13006 T14633 T14633 ROOT shown,shown
R13007 T14634 T14633 prep with,shown
R13008 T14635 T14636 det a,graph
R13009 T14636 T14634 pobj graph,with
R13010 T14637 T14636 prep of,graph
R13011 T14638 T14642 det the,values
R13012 T14639 T14642 amod averaged,values
R13013 T14640 T14642 compound fluorescence,values
R13014 T14641 T14642 compound intensity,values
R13015 T14642 T14637 pobj values,of
R13016 T14643 T14642 prep over,values
R13017 T14644 T14645 nummod 3,experiments
R13018 T14645 T14643 pobj experiments,over
R13019 T14646 T14633 punct .,shown
R4609 T5326 T5327 amod Bay11-7082,inhibits
R4610 T5327 T5327 ROOT inhibits,inhibits
R4611 T5328 T5329 compound pro-IL-1β,production
R4612 T5329 T5327 dobj production,inhibits
R4613 T5330 T5327 prep in,inhibits
R4614 T5331 T5330 pobj response,in
R4615 T5332 T5331 prep to,response
R4616 T5333 T5334 compound P.,aeruginosa
R4617 T5334 T5332 pobj aeruginosa,to
R4618 T5335 T5347 prep In,inhibit
R4619 T5336 T5335 pobj addition,In
R4620 T5337 T5336 prep to,addition
R4621 T5338 T5337 pobj inhibition,to
R4622 T5339 T5338 prep of,inhibition
R4623 T5340 T5341 amod NF-κB,activity
R4624 T5341 T5339 pobj activity,of
R4625 T5342 T5347 punct ",",inhibit
R4626 T5343 T5347 nsubj Bay11-7082,inhibit
R4627 T5344 T5347 aux can,inhibit
R4628 T5345 T5347 advmod also,inhibit
R4629 T5346 T5347 advmod directly,inhibit
R4630 T5347 T5347 ROOT inhibit,inhibit
R4631 T5348 T5351 det the,[
R4632 T5349 T5351 nmod NLRP3,[
R4633 T5350 T5351 compound inflammasome,[
R4634 T5351 T5347 dobj [,inhibit
R4635 T5352 T5353 nummod 38,]
R4636 T5353 T5351 appos ],[
R4637 T5354 T5347 punct .,inhibit
R4638 T5355 T5356 aux To,validate
R4639 T5356 T5372 advcl validate,performed
R4640 T5357 T5358 poss its,use
R4641 T5358 T5356 dobj use,validate
R4642 T5359 T5358 prep in,use
R4643 T5360 T5361 det this,study
R4644 T5361 T5359 pobj study,in
R4645 T5362 T5356 prep as,validate
R4646 T5363 T5365 det an,inhibitor
R4647 T5364 T5365 amod NF-κB,inhibitor
R4648 T5365 T5362 pobj inhibitor,as
R4649 T5366 T5365 punct ",",inhibitor
R4650 T5367 T5368 amod western,blots
R4651 T5368 T5372 nsubjpass blots,performed
R4652 T5369 T5368 prep for,blots
R4653 T5370 T5369 pobj pro-IL-1β,for
R4654 T5371 T5372 auxpass were,performed
R4655 T5372 T5372 ROOT performed,performed
R4656 T5373 T5372 prep alongside,performed
R4657 T5374 T5373 pobj inhibition,alongside
R4658 T5375 T5374 prep of,inhibition
R4659 T5376 T5377 amod CFTR,activity
R4660 T5377 T5375 pobj activity,of
R4661 T5378 T5372 agent by,performed
R4662 T5379 T5378 pobj CFTRinh172,by
R4663 T5380 T5372 prep in,performed
R4664 T5381 T5380 pobj response,in
R4665 T5382 T5381 prep to,response
R4666 T5383 T5382 pobj PAO1,to
R4667 T5384 T5372 prep at,performed
R4668 T5385 T5386 nummod 4,hours
R4669 T5386 T5387 npadvmod hours,after
R4670 T5387 T5372 prep after,performed
R4671 T5388 T5387 pobj stimulation,after
R4672 T5389 T5372 punct (,performed
R4673 T5390 T5392 nmod Fig.,)
R4674 T5391 T5390 nummod 7a,Fig.
R4675 T5392 T5372 punct ),performed
R4676 T5393 T5372 punct .,performed
R4677 T5394 T5395 poss Our,results
R4678 T5395 T5396 nsubj results,indicate
R4679 T5396 T5396 ROOT indicate,indicate
R4680 T5397 T5399 mark that,prevents
R4681 T5398 T5399 nsubj Bay11-7082,prevents
R4682 T5399 T5396 ccomp prevents,indicate
R4683 T5400 T5399 dobj production,prevents
R4684 T5401 T5400 prep of,production
R4685 T5402 T5401 pobj pro-IL-1β,of
R4686 T5403 T5407 mark whereas,seem
R4687 T5404 T5407 nsubj CFTRinh172,seem
R4688 T5405 T5407 aux does,seem
R4689 T5406 T5407 neg not,seem
R4690 T5407 T5399 advcl seem,prevents
R4691 T5408 T5409 aux to,affect
R4692 T5409 T5407 xcomp affect,seem
R4693 T5410 T5409 dobj it,affect
R4694 T5411 T5396 punct .,indicate
R4695 T5412 T5415 nsubjpass This,corroborated
R4696 T5413 T5415 auxpass was,corroborated
R4697 T5414 T5415 advmod further,corroborated
R4698 T5415 T5415 ROOT corroborated,corroborated
R4699 T5416 T5415 agent by,corroborated
R4700 T5417 T5418 det the,ability
R4701 T5418 T5416 pobj ability,by
R4702 T5419 T5418 amod Bay11-7082,ability
R4703 T5420 T5421 aux to,inhibit
R4704 T5421 T5418 acl inhibit,ability
R4705 T5422 T5423 compound IκBα,degradation
R4706 T5423 T5421 dobj degradation,inhibit
R4707 T5424 T5423 prep at,degradation
R4708 T5425 T5424 pobj 0.5,at
R4709 T5426 T5425 punct ",",0.5
R4710 T5427 T5425 conj 1,0.5
R4711 T5428 T5421 punct ",",inhibit
R4712 T5429 T5421 cc and,inhibit
R4713 T5430 T5431 nummod 1.5,hours
R4714 T5431 T5432 compound hours,post
R4715 T5432 T5421 conj post,inhibit
R4716 T5433 T5434 nummod PAO1,stimulation
R4717 T5434 T5432 dobj stimulation,post
R4718 T5435 T5432 punct (,post
R4719 T5436 T5438 nmod Fig.,)
R4720 T5437 T5436 nummod 7b,Fig.
R4721 T5438 T5432 punct ),post
R4722 T5439 T5415 punct .,corroborated