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PMC:3342329 / 3136-4458 JSONTXT 24 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T3431 0-13 NN denotes Interleukin-1
T3432 14-22 NN denotes receptor
T3433 23-33 NN denotes antagonist
T3434 34-35 -LRB- denotes (
T3435 35-41 NN denotes IL-1Ra
T3436 41-42 -RRB- denotes )
T3437 42-43 , denotes ,
T3438 44-45 DT denotes a
T3439 46-52 NN denotes member
T3440 53-55 IN denotes of
T3441 56-59 DT denotes the
T3442 60-64 NNP denotes IL-1
T3443 65-71 NN denotes family
T3444 71-72 , denotes ,
T3445 73-75 VBZ denotes is
T3446 76-77 DT denotes a
T3447 78-87 RB denotes naturally
T3448 88-97 VBG denotes occurring
T3449 98-106 NN denotes cytokine
T3450 107-111 WDT denotes that
T3451 112-125 RB denotes competitively
T3452 126-132 VBZ denotes blocks
T3453 133-136 DT denotes the
T3454 137-141 NN denotes IL-1
T3455 142-150 NN denotes receptor
T3456 151-152 NNP denotes [
T3457 152-154 CD denotes 13
T3458 154-155 NNP denotes ]
T3459 155-156 . denotes .
T3460 157-164 IN denotes Because
T3461 165-171 NN denotes IL-1Ra
T3462 172-175 VBZ denotes has
T3463 176-180 VBN denotes been
T3464 181-186 VBN denotes shown
T3465 187-189 TO denotes to
T3466 190-197 VB denotes inhibit
T3467 198-203 NN denotes tumor
T3468 204-215 NN denotes progression
T3469 216-218 IN denotes by
T3470 219-228 VBG denotes promoting
T3471 229-238 JJ denotes antitumor
T3472 239-245 JJ denotes immune
T3473 246-255 NNS denotes responses
T3474 256-259 CC denotes and
T3475 260-262 IN denotes by
T3476 263-272 VBG denotes enhancing
T3477 273-276 DT denotes the
T3478 277-285 NN denotes activity
T3479 286-288 IN denotes of
T3480 289-301 JJ denotes chemotherapy
T3481 301-302 , denotes ,
T3482 303-311 JJ denotes numerous
T3483 312-319 NNS denotes studies
T3484 320-324 VBP denotes have
T3485 325-333 VBN denotes examined
T3486 334-337 DT denotes the
T3487 338-345 NN denotes ability
T3488 346-348 IN denotes of
T3489 349-355 NN denotes IL-1Ra
T3490 356-358 TO denotes to
T3491 359-364 VB denotes block
T3492 365-370 NN denotes tumor
T3493 371-382 NN denotes progression
T3494 382-383 . denotes .
T3495 384-390 NN denotes IL-1Ra
T3496 391-401 NN denotes expression
T3497 402-405 VBD denotes was
T3498 406-413 VBN denotes reduced
T3499 414-416 IN denotes in
T3500 417-425 NN denotes prostate
T3501 426-427 NNP denotes [
T3502 427-429 CD denotes 14
T3503 429-430 NNP denotes ]
T3504 430-431 , denotes ,
T3505 432-438 NN denotes breast
T3506 439-440 NNP denotes [
T3507 440-442 CD denotes 15
T3508 442-443 NNP denotes ]
T3509 443-444 , denotes ,
T3510 445-448 CC denotes and
T3511 449-453 NN denotes skin
T3512 454-460 NN denotes cancer
T3513 461-462 NNP denotes [
T3514 462-464 CD denotes 16
T3515 464-465 NNP denotes ]
T3516 465-466 . denotes .
T3517 467-469 PRP denotes It
T3518 470-473 VBD denotes was
T3519 474-478 RB denotes also
T3520 479-487 VBN denotes reported
T3521 488-492 IN denotes that
T3522 493-503 JJ denotes endogenous
T3523 504-510 NN denotes IL-1Ra
T3524 511-520 NN denotes deficient
T3525 521-525 NNS denotes mice
T3526 526-535 VBD denotes developed
T3527 536-546 JJ denotes aggressive
T3528 547-553 NNS denotes tumors
T3529 554-563 VBG denotes following
T3530 564-572 NN denotes exposure
T3531 573-575 TO denotes to
T3532 576-587 NNS denotes carcinogens
T3533 588-589 NNP denotes [
T3534 589-591 CD denotes 17
T3535 591-592 NNP denotes ]
T3536 592-593 . denotes .
T3537 594-603 RB denotes Meanwhile
T3538 603-604 , denotes ,
T3539 605-618 NN denotes proliferation
T3540 619-621 IN denotes of
T3541 622-625 DT denotes the
T3542 626-634 NN denotes melanoma
T3543 635-640 NNS denotes cells
T3544 641-645 WDT denotes that
T3545 646-650 VBD denotes were
T3546 651-661 VBN denotes transduced
T3547 662-666 IN denotes with
T3548 667-673 JJ denotes IL-1Ra
T3549 674-678 NN denotes gene
T3550 679-682 VBD denotes was
T3551 683-690 VBN denotes reduced
T3552 691-694 CC denotes and
T3553 695-704 VBN denotes inhibited
T3554 705-713 NN denotes melanoma
T3555 714-725 NN denotes development
T3556 726-727 NNP denotes [
T3557 727-729 CD denotes 18
T3558 729-730 NNP denotes ]
T3559 730-731 . denotes .
T3560 732-737 NN denotes IL-1R
T3561 738-746 NN denotes blockade
T3562 747-751 RB denotes also
T3563 752-759 VBD denotes reduced
T3564 760-767 JJ denotes hepatic
T3565 768-773 NN denotes tumor
T3566 774-780 NN denotes growth
T3567 781-782 NNP denotes [
T3568 782-784 CD denotes 19
T3569 784-785 NNP denotes ]
T3570 785-786 . denotes .
T3571 787-795 RB denotes Moreover
T3572 795-796 , denotes ,
T3573 797-799 PRP denotes it
T3574 800-803 VBZ denotes has
T3575 804-808 RB denotes also
T3576 809-813 VBN denotes been
T3577 814-822 VBN denotes reported
T3578 823-827 IN denotes that
T3579 828-834 JJ denotes IL-1Ra
T3580 835-842 VBZ denotes reduces
T3581 843-855 NN denotes fibrosarcoma
T3582 856-867 NN denotes development
T3583 868-869 NNP denotes [
T3584 869-871 CD denotes 20
T3585 871-872 NNP denotes ]
T3586 872-873 , denotes ,
T3587 874-877 NNP denotes B16
T3588 878-886 NN denotes melanoma
T3589 887-893 NN denotes growth
T3590 894-897 CC denotes and
T3591 898-908 NN denotes metastasis
T3592 909-910 NNP denotes [
T3593 910-912 CD denotes 21
T3594 912-913 NNP denotes ]
T3595 913-914 , denotes ,
T3596 915-920 NN denotes colon
T3597 921-935 NN denotes adenocarcinoma
T3598 936-942 NN denotes growth
T3599 943-944 NNP denotes [
T3600 944-946 CD denotes 22
T3601 946-947 NNP denotes ]
T3602 947-948 , denotes ,
T3603 949-952 CC denotes and
T3604 953-957 NN denotes skin
T3605 958-964 NN denotes cancer
T3606 965-976 NN denotes development
T3607 977-978 NNP denotes [
T3608 978-980 CD denotes 23
T3609 980-981 NNP denotes ]
T3610 981-982 . denotes .
T3611 983-987 CD denotes IL-1
T3612 988-996 NN denotes knockout
T3613 997-1001 NNS denotes mice
T3614 1002-1010 VBN denotes injected
T3615 1011-1015 IN denotes with
T3616 1016-1024 NN denotes melanoma
T3617 1025-1031 VBD denotes failed
T3618 1032-1034 TO denotes to
T3619 1035-1042 VB denotes develop
T3620 1043-1048 JJ denotes solid
T3621 1049-1055 NNS denotes tumors
T3622 1056-1057 NNP denotes [
T3623 1057-1059 CD denotes 24
T3624 1059-1060 NNP denotes ]
T3625 1060-1061 . denotes .
T3626 1062-1064 PRP denotes It
T3627 1065-1068 VBD denotes was
T3628 1069-1073 RB denotes also
T3629 1074-1079 VBN denotes found
T3630 1080-1084 IN denotes that
T3631 1085-1091 NN denotes IL-1Ra
T3632 1091-1092 , denotes ,
T3633 1093-1101 VBN denotes combined
T3634 1102-1106 IN denotes with
T3635 1107-1119 NN denotes temozolomide
T3636 1120-1123 CC denotes and
T3637 1124-1133 NN denotes docetaxel
T3638 1134-1146 NN denotes chemotherapy
T3639 1146-1147 , denotes ,
T3640 1148-1160 VBD denotes demonstrated
T3641 1161-1165 RBR denotes more
T3642 1166-1177 JJ denotes significant
T3643 1178-1187 NN denotes antitumor
T3644 1188-1196 NN denotes activity
T3645 1197-1204 IN denotes against
T3646 1205-1208 NNP denotes B16
T3647 1209-1217 NN denotes melanoma
T3648 1218-1223 NNS denotes cells
T3649 1224-1226 IN denotes in
T3650 1227-1231 NN denotes vivo
T3651 1232-1233 NNP denotes [
T3652 1233-1235 CD denotes 25
T3653 1235-1236 NNP denotes ]
T3654 1236-1237 . denotes .
T3655 1238-1243 DT denotes These
T3656 1244-1248 NNS denotes data
T3657 1249-1257 VBP denotes indicate
T3658 1258-1262 IN denotes that
T3659 1263-1269 NN denotes IL-1Ra
T3660 1270-1272 VBZ denotes is
T3661 1273-1282 JJ denotes important
T3662 1283-1285 IN denotes as
T3663 1286-1287 DT denotes a
T3664 1288-1293 NN denotes tumor
T3665 1294-1300 NN denotes growth
T3666 1301-1312 VBG denotes suppressing
T3667 1313-1321 NN denotes cytokine
T3668 1321-1322 . denotes .
R2244 T3431 T3433 compound Interleukin-1,antagonist
R2246 T3432 T3433 compound receptor,antagonist
R2247 T3433 T3445 nsubj antagonist,is
R2248 T3434 T3433 punct (,antagonist
R2249 T3435 T3433 appos IL-1Ra,antagonist
R2251 T3436 T3433 punct ),antagonist
R2252 T3437 T3433 punct ",",antagonist
R2253 T3438 T3439 det a,member
R2254 T3439 T3433 appos member,antagonist
R2255 T3440 T3439 prep of,member
R2256 T3441 T3443 det the,family
R2257 T3442 T3443 amod IL-1,family
R2259 T3443 T3440 pobj family,of
R2260 T3444 T3445 punct ",",is
R2261 T3445 T3445 ROOT is,is
R2262 T3446 T3449 det a,cytokine
R2264 T3447 T3448 advmod naturally,occurring
R2265 T3448 T3449 amod occurring,cytokine
R2266 T3449 T3445 attr cytokine,is
R2268 T3450 T3452 nsubj that,blocks
R2269 T3451 T3452 advmod competitively,blocks
R2270 T3452 T3449 relcl blocks,cytokine
R2272 T3453 T3455 det the,receptor
R2273 T3454 T3455 amod IL-1,receptor
R2274 T3455 T3452 dobj receptor,blocks
R2276 T3456 T3458 nmod [,]
R2277 T3457 T3458 nummod 13,]
R2278 T3458 T3449 appos ],cytokine
R2280 T3459 T3445 punct .,is
R2281 T3460 T3464 mark Because,shown
R2282 T3461 T3464 nsubjpass IL-1Ra,shown
R2284 T3462 T3464 aux has,shown
R2285 T3463 T3464 auxpass been,shown
R2286 T3464 T3464 ROOT shown,shown
R2287 T3465 T3466 aux to,inhibit
R2289 T3466 T3464 xcomp inhibit,shown
R2290 T3467 T3468 compound tumor,progression
R2291 T3468 T3466 dobj progression,inhibit
R2293 T3469 T3466 prep by,inhibit
R2294 T3470 T3469 pcomp promoting,by
R2295 T3471 T3473 amod antitumor,responses
R2297 T3472 T3473 amod immune,responses
R2298 T3473 T3470 dobj responses,promoting
R2299 T3474 T3469 cc and,by
R2301 T3475 T3469 conj by,by
R2302 T3476 T3475 pcomp enhancing,by
R2303 T3477 T3478 det the,activity
R2304 T3478 T3476 dobj activity,enhancing
R2305 T3479 T3478 prep of,activity
R2306 T3480 T3483 amod chemotherapy,studies
R2308 T3481 T3483 punct ",",studies
R2309 T3482 T3483 amod numerous,studies
R2310 T3483 T3479 pobj studies,of
R2313 T3484 T3485 aux have,examined
R2316 T3485 T3464 conj examined,shown
R2318 T3486 T3487 det the,ability
R2322 T3487 T3485 dobj ability,examined
R2325 T3488 T3487 prep of,ability
R2328 T3489 T3488 pobj IL-1Ra,of
R2331 T3490 T3491 aux to,block
R2333 T3491 T3487 acl block,ability
R2336 T3492 T3493 compound tumor,progression
R2337 T3493 T3491 dobj progression,block
R2339 T3494 T3464 punct .,shown
R2340 T3495 T3496 compound IL-1Ra,expression
R2341 T3496 T3498 nsubjpass expression,reduced
R2343 T3497 T3498 auxpass was,reduced
R2344 T3498 T3498 ROOT reduced,reduced
R2345 T3499 T3498 prep in,reduced
R2347 T3500 T3499 pobj prostate,in
R2348 T3501 T3503 nmod [,]
R2350 T3502 T3503 nummod 14,]
R2351 T3503 T3498 npadvmod ],reduced
R2352 T3504 T3503 punct ",",]
R2353 T3505 T3506 compound breast,[
R2356 T3506 T3503 conj [,]
R2358 T3507 T3508 nummod 15,]
R2359 T3508 T3506 conj ],[
R2360 T3509 T3508 punct ",",]
R2361 T3603 T3601 cc and,]
R2362 T3510 T3508 cc and,]
R2363 T3511 T3512 compound skin,cancer
R2364 T3512 T3513 compound cancer,[
R2365 T3604 T3605 compound skin,cancer
R2366 T3513 T3508 conj [,]
R2367 T3514 T3515 nummod 16,]
R2368 T3515 T3513 appos ],[
R2369 T3516 T3498 punct .,reduced
R2370 T3605 T3606 compound cancer,development
R2371 T3517 T3520 nsubjpass It,reported
R2372 T3518 T3520 auxpass was,reported
R2373 T3519 T3520 advmod also,reported
R2374 T3606 T3580 dobj development,reduces
R2375 T3520 T3520 ROOT reported,reported
R2376 T3521 T3526 mark that,developed
R2377 T3522 T3525 amod endogenous,mice
R2378 T3607 T3609 nmod [,]
R2379 T3523 T3525 compound IL-1Ra,mice
R2380 T3524 T3525 compound deficient,mice
R2381 T3525 T3526 nsubj mice,developed
R2382 T3608 T3609 nummod 23,]
R2383 T3526 T3520 ccomp developed,reported
R2384 T3527 T3528 amod aggressive,tumors
R2385 T3528 T3526 dobj tumors,developed
R2386 T3609 T3580 npadvmod ],reduces
R2387 T3529 T3526 prep following,developed
R2388 T3530 T3529 pobj exposure,following
R2389 T3531 T3530 prep to,exposure
R2390 T3610 T3577 punct .,reported
R2391 T3532 T3531 pobj carcinogens,to
R2392 T3533 T3535 nmod [,]
R2393 T3534 T3533 nummod 17,[
R2394 T3611 T3613 nummod IL-1,mice
R2395 T3535 T3532 appos ],carcinogens
R2396 T3536 T3520 punct .,reported
R2397 T3612 T3613 compound knockout,mice
R2398 T3537 T3551 advmod Meanwhile,reduced
R2399 T3538 T3551 punct ",",reduced
R2400 T3539 T3551 nsubjpass proliferation,reduced
R2401 T3613 T3617 nsubj mice,failed
R2402 T3540 T3539 prep of,proliferation
R2403 T3541 T3543 det the,cells
R2404 T3542 T3543 compound melanoma,cells
R2405 T3543 T3540 pobj cells,of
R2406 T3544 T3546 nsubjpass that,transduced
R2407 T3545 T3546 auxpass were,transduced
R2408 T3614 T3613 acl injected,mice
R2409 T3546 T3543 relcl transduced,cells
R2410 T3547 T3546 prep with,transduced
R2411 T3548 T3549 amod IL-1Ra,gene
R2412 T3615 T3614 prep with,injected
R2413 T3549 T3547 pobj gene,with
R2414 T3550 T3551 auxpass was,reduced
R2415 T3551 T3551 ROOT reduced,reduced
R2416 T3616 T3615 pobj melanoma,with
R2417 T3552 T3551 cc and,reduced
R2418 T3553 T3551 conj inhibited,reduced
R2419 T3554 T3555 compound melanoma,development
R2420 T3555 T3553 dobj development,inhibited
R2421 T3617 T3617 ROOT failed,failed
R2422 T3556 T3558 nmod [,]
R2423 T3557 T3558 nummod 18,]
R2424 T3558 T3555 appos ],development
R2425 T3618 T3619 aux to,develop
R2426 T3559 T3551 punct .,reduced
R2427 T3560 T3561 compound IL-1R,blockade
R2428 T3561 T3563 nsubj blockade,reduced
R2429 T3619 T3617 xcomp develop,failed
R2430 T3620 T3621 amod solid,tumors
R2431 T3562 T3563 advmod also,reduced
R2432 T3621 T3619 dobj tumors,develop
R2433 T3563 T3563 ROOT reduced,reduced
R2434 T3564 T3566 amod hepatic,growth
R2435 T3622 T3624 nsubj [,]
R2436 T3565 T3566 compound tumor,growth
R2437 T3566 T3563 dobj growth,reduced
R2438 T3567 T3569 nmod [,]
R2439 T3623 T3624 nummod 24,]
R2440 T3568 T3569 nummod 19,]
R2441 T3569 T3566 appos ],growth
R2442 T3624 T3617 dep ],failed
R2443 T3570 T3563 punct .,reduced
R2444 T3625 T3617 punct .,failed
R2445 T3571 T3577 advmod Moreover,reported
R2446 T3572 T3577 punct ",",reported
R2447 T3573 T3577 nsubj it,reported
R2448 T3626 T3629 nsubjpass It,found
R2449 T3574 T3577 aux has,reported
R2450 T3575 T3577 advmod also,reported
R2451 T3576 T3577 auxpass been,reported
R2452 T3627 T3629 auxpass was,found
R2453 T3577 T3577 ROOT reported,reported
R2454 T3578 T3580 mark that,reduces
R2455 T3579 T3580 nsubj IL-1Ra,reduces
R2456 T3580 T3577 ccomp reduces,reported
R2457 T3581 T3582 compound fibrosarcoma,development
R2458 T3582 T3580 dobj development,reduces
R2459 T3628 T3629 advmod also,found
R2460 T3583 T3585 nmod [,]
R2461 T3584 T3585 nummod 20,]
R2462 T3585 T3606 nmod ],development
R2463 T3629 T3629 ROOT found,found
R2464 T3586 T3585 punct ",",]
R2465 T3587 T3589 compound B16,growth
R2466 T3588 T3589 compound melanoma,growth
R2467 T3630 T3640 mark that,demonstrated
R2468 T3589 T3585 appos growth,]
R2469 T3590 T3589 cc and,growth
R2470 T3591 T3592 compound metastasis,[
R2471 T3631 T3640 nsubj IL-1Ra,demonstrated
R2472 T3592 T3585 conj [,]
R2473 T3593 T3594 nummod 21,]
R2474 T3594 T3594 ROOT ],]
R2475 T3632 T3631 punct ",",IL-1Ra
R2476 T3595 T3594 punct ",",]
R2477 T3596 T3597 compound colon,adenocarcinoma
R2478 T3597 T3598 compound adenocarcinoma,growth
R2479 T3633 T3631 acl combined,IL-1Ra
R2480 T3598 T3599 compound growth,[
R2481 T3599 T3592 conj [,[
R2482 T3600 T3601 nummod 22,]
R2483 T3634 T3633 prep with,combined
R2484 T3601 T3599 conj ],[
R2485 T3602 T3601 punct ",",]
R2486 T3635 T3634 pobj temozolomide,with
R2487 T3636 T3635 cc and,temozolomide
R2488 T3637 T3635 conj docetaxel,temozolomide
R2489 T3638 T3635 conj chemotherapy,temozolomide
R2490 T3639 T3640 punct ",",demonstrated
R2491 T3661 T3660 acomp important,is
R2492 T3640 T3629 ccomp demonstrated,found
R2493 T3662 T3661 prep as,important
R2494 T3663 T3665 det a,growth
R2495 T3664 T3665 compound tumor,growth
R2496 T3641 T3642 advmod more,significant
R2497 T3665 T3666 npadvmod growth,suppressing
R2498 T3666 T3662 pcomp suppressing,as
R2499 T3667 T3666 dobj cytokine,suppressing
R2500 T3642 T3644 amod significant,activity
R2501 T3668 T3657 punct .,indicate
R2504 T3643 T3644 compound antitumor,activity
R2512 T3644 T3640 dobj activity,demonstrated
R2517 T3645 T3644 prep against,activity
R2521 T3646 T3648 compound B16,cells
R2525 T3647 T3648 compound melanoma,cells
R2529 T3648 T3645 pobj cells,against
R2533 T3649 T3648 prep in,cells
R2537 T3650 T3651 compound vivo,[
R2541 T3651 T3649 pobj [,in
R2542 T3652 T3653 nummod 25,]
R2544 T3653 T3651 appos ],[
R2547 T3654 T3629 punct .,found
R2551 T3655 T3656 det These,data
R2558 T3656 T3657 nsubj data,indicate
R2563 T3657 T3657 ROOT indicate,indicate
R2567 T3658 T3660 mark that,is
R2571 T3659 T3660 nsubj IL-1Ra,is
R2575 T3660 T3657 ccomp is,indicate