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PMC:3342329 / 21382-23408 JSONTXT 25 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T12135 0-8 JJ denotes Numerous
T12136 9-16 NNS denotes studies
T12137 17-23 VBD denotes showed
T12138 24-28 IN denotes that
T12139 29-37 JJ denotes cytokine
T12140 38-44 VB denotes affect
T12141 45-50 NN denotes tumor
T12142 51-57 NN denotes growth
T12143 58-60 IN denotes by
T12144 61-71 VBG denotes regulating
T12145 72-77 NNP denotes NF-κB
T12146 77-78 . denotes .
T12147 79-91 JJ denotes Inflammatory
T12148 92-101 NNS denotes cytokines
T12149 101-102 , denotes ,
T12150 103-112 VBG denotes including
T12151 113-117 NNP denotes IL-1
T12152 117-118 , denotes ,
T12153 119-123 NNP denotes IL-6
T12154 124-127 CC denotes and
T12155 128-132 NNP denotes IL-8
T12156 132-133 , denotes ,
T12157 134-142 VBP denotes activate
T12158 143-148 JJ denotes NF-κB
T12159 149-157 NNS denotes pathways
T12160 158-160 IN denotes in
T12161 161-166 NN denotes tumor
T12162 167-172 NNS denotes cells
T12163 173-174 NNP denotes [
T12164 174-176 CD denotes 41
T12165 176-177 NNP denotes ]
T12166 177-178 . denotes .
T12167 179-182 DT denotes The
T12168 183-194 NN denotes interleukin
T12169 195-197 CD denotes 10
T12170 198-199 -LRB- denotes (
T12171 199-204 NN denotes IL-10
T12172 204-205 -RRB- denotes )
T12173 206-208 VBZ denotes is
T12174 209-213 RB denotes well
T12175 214-219 VBN denotes known
T12176 220-222 IN denotes as
T12177 223-225 DT denotes an
T12178 226-236 JJ denotes anti-tumor
T12179 237-243 NN denotes factor
T12180 244-246 RB denotes as
T12181 247-251 RB denotes well
T12182 252-254 IN denotes as
T12183 255-257 DT denotes an
T12184 258-275 JJ denotes anti-inflammatory
T12185 276-282 NN denotes factor
T12186 283-284 NNP denotes [
T12187 284-286 CD denotes 42
T12188 286-287 NNP denotes ]
T12189 287-288 , denotes ,
T12190 289-290 NNP denotes [
T12191 290-292 CD denotes 43
T12192 292-293 NNP denotes ]
T12193 293-294 . denotes .
T12194 295-300 JJ denotes IL-10
T12195 301-309 NNS denotes inhibits
T12196 310-324 RB denotes constitutively
T12197 325-334 VBD denotes activated
T12198 335-340 NNP denotes NF-κB
T12199 341-345 DT denotes both
T12200 346-348 IN denotes in
T12201 349-354 NN denotes vitro
T12202 355-356 NNP denotes [
T12203 356-358 CD denotes 44
T12204 358-359 NNP denotes ]
T12205 360-363 CC denotes and
T12206 364-366 IN denotes in
T12207 367-371 NN denotes vivo
T12208 372-373 NNP denotes [
T12209 373-375 CD denotes 45
T12210 375-376 NNP denotes ]
T12211 376-377 . denotes .
T12212 378-388 NNP denotes Inhibition
T12213 389-391 IN denotes of
T12214 392-397 NNP denotes NF-κB
T12215 398-400 IN denotes by
T12216 401-404 DT denotes the
T12217 405-410 NNP denotes IL-10
T12218 411-422 VBZ denotes contributes
T12219 423-425 TO denotes to
T12220 426-429 DT denotes the
T12221 430-440 JJ denotes anti-tumor
T12222 441-448 NNS denotes effects
T12223 449-456 IN denotes through
T12224 457-460 DT denotes the
T12225 461-471 NN denotes activation
T12226 472-474 IN denotes of
T12227 475-484 JJ denotes caspase-3
T12228 485-488 CC denotes and
T12229 489-498 NN denotes apoptosis
T12230 499-501 IN denotes in
T12231 502-517 JJ denotes Colon26-bearing
T12232 518-522 NNS denotes mice
T12233 523-524 NNP denotes [
T12234 524-526 CD denotes 43
T12235 526-527 NNP denotes ]
T12236 527-528 . denotes .
T12237 529-538 RB denotes Similarly
T12238 538-539 , denotes ,
T12239 540-547 JJ denotes several
T12240 548-555 NNS denotes studies
T12241 556-560 VBP denotes have
T12242 561-573 VBN denotes demonstrated
T12243 574-577 DT denotes the
T12244 578-585 NN denotes ability
T12245 586-588 IN denotes of
T12246 589-595 NN denotes IL-1Ra
T12247 596-598 TO denotes to
T12248 599-607 VB denotes abrogate
T12249 608-611 DT denotes the
T12250 612-627 JJ denotes proinflammatory
T12251 628-635 NNS denotes effects
T12252 636-638 IN denotes of
T12253 639-643 NNP denotes IL-1
T12254 644-645 NNP denotes [
T12255 645-647 CD denotes 46
T12256 647-648 NNP denotes ]
T12257 648-649 . denotes .
T12258 650-652 PRP denotes It
T12259 653-656 VBZ denotes has
T12260 657-661 VBN denotes been
T12261 662-670 VBN denotes reported
T12262 671-675 IN denotes that
T12263 676-680 JJ denotes IL-1
T12264 681-688 VBZ denotes induces
T12265 689-692 DT denotes the
T12266 693-703 NN denotes activation
T12267 704-706 IN denotes of
T12268 707-712 NN denotes NF-κB
T12269 713-715 IN denotes in
T12270 716-723 JJ denotes several
T12271 724-731 NNS denotes cancers
T12272 731-732 , denotes ,
T12273 733-736 CC denotes and
T12274 737-746 VBZ denotes increases
T12275 747-751 NN denotes cell
T12276 752-757 NN denotes cycle
T12277 758-769 NN denotes progression
T12278 769-770 , denotes ,
T12279 771-774 CC denotes and
T12280 775-778 DT denotes the
T12281 779-790 NN denotes suppression
T12282 791-793 IN denotes of
T12283 794-803 JJ denotes apoptotic
T12284 804-808 NN denotes cell
T12285 809-814 NN denotes death
T12286 815-822 VBG denotes leading
T12287 823-825 TO denotes to
T12288 826-831 NN denotes tumor
T12289 832-841 NN denotes promotion
T12290 841-842 . denotes .
T12291 843-846 DT denotes The
T12292 847-854 NNS denotes results
T12293 855-857 IN denotes of
T12294 858-865 JJ denotes various
T12295 866-873 NNS denotes studies
T12296 874-878 IN denotes over
T12297 879-882 DT denotes the
T12298 883-887 JJ denotes past
T12299 888-890 CD denotes 10
T12300 891-896 NNS denotes years
T12301 897-905 VBP denotes indicate
T12302 906-910 IN denotes that
T12303 911-914 DT denotes the
T12304 915-920 JJ denotes major
T12305 921-929 NN denotes function
T12306 930-932 IN denotes of
T12307 933-939 NN denotes IL-1Ra
T12308 940-942 VBZ denotes is
T12309 943-945 TO denotes to
T12310 946-954 VB denotes regulate
T12311 955-958 DT denotes the
T12312 959-970 JJ denotes pleiotropic
T12313 971-978 NNS denotes effects
T12314 979-981 IN denotes of
T12315 982-986 NN denotes IL-1
T12316 987-989 IN denotes by
T12317 990-1003 RB denotes competitively
T12318 1004-1012 VBG denotes blocking
T12319 1013-1016 PRP$ denotes its
T12320 1017-1026 NNS denotes functions
T12321 1027-1028 NNP denotes [
T12322 1028-1030 CD denotes 47
T12323 1030-1031 NNP denotes ]
T12324 1031-1032 . denotes .
T12325 1033-1036 DT denotes The
T12326 1037-1044 NN denotes ability
T12327 1045-1047 IN denotes of
T12328 1048-1052 NN denotes IL-1
T12329 1053-1055 TO denotes to
T12330 1056-1062 VB denotes induce
T12331 1063-1066 PRP$ denotes its
T12332 1067-1070 JJ denotes own
T12333 1071-1081 NN denotes antagonist
T12334 1082-1084 VBZ denotes is
T12335 1085-1087 IN denotes of
T12336 1088-1096 NN denotes interest
T12337 1097-1099 IN denotes in
T12338 1100-1113 VBG denotes understanding
T12339 1114-1117 DT denotes the
T12340 1118-1128 NN denotes regulation
T12341 1129-1132 CC denotes and
T12342 1133-1146 NN denotes dysregulation
T12343 1147-1149 IN denotes of
T12344 1150-1154 JJ denotes IL-1
T12345 1155-1164 VBG denotes signaling
T12346 1165-1167 IN denotes in
T12347 1168-1174 JJ denotes normal
T12348 1175-1178 CC denotes and
T12349 1179-1187 JJ denotes diseased
T12350 1188-1194 NN denotes tissue
T12351 1194-1195 . denotes .
T12352 1196-1209 NN denotes Up-regulation
T12353 1210-1212 IN denotes of
T12354 1213-1216 DT denotes the
T12355 1217-1225 NN denotes receptor
T12356 1226-1236 NN denotes antagonist
T12357 1237-1247 VBZ denotes represents
T12358 1248-1249 DT denotes a
T12359 1250-1259 NN denotes mechanism
T12360 1260-1263 IN denotes for
T12361 1264-1271 VBG denotes turning
T12362 1272-1275 RP denotes off
T12363 1276-1280 JJ denotes IL-1
T12364 1281-1290 VBG denotes signaling
T12365 1291-1294 CC denotes and
T12366 1295-1303 VBG denotes creating
T12367 1304-1305 DT denotes a
T12368 1306-1315 JJ denotes temporary
T12369 1316-1321 NN denotes state
T12370 1322-1324 IN denotes of
T12371 1325-1339 NN denotes refractoriness
T12372 1339-1340 . denotes .
T12373 1341-1344 DT denotes The
T12374 1345-1353 JJ denotes elevated
T12375 1354-1364 NN denotes expression
T12376 1365-1367 IN denotes of
T12377 1368-1374 NN denotes IL-1Ra
T12378 1374-1375 , denotes ,
T12379 1376-1383 IN denotes without
T12380 1384-1387 DT denotes any
T12381 1388-1394 NN denotes change
T12382 1395-1397 IN denotes of
T12383 1398-1402 NN denotes IL-1
T12384 1403-1405 IN denotes in
T12385 1406-1412 NNS denotes tumors
T12386 1412-1413 , denotes ,
T12387 1414-1422 VBZ denotes suggests
T12388 1423-1427 IN denotes that
T12389 1428-1431 DT denotes the
T12390 1432-1446 JJ denotes IL-1-signaling
T12391 1447-1453 NN denotes system
T12392 1454-1457 MD denotes may
T12393 1458-1460 VB denotes be
T12394 1461-1473 VBN denotes dysregulated
T12395 1474-1476 IN denotes by
T12396 1477-1483 NN denotes IL-1Ra
T12397 1484-1486 IN denotes in
T12398 1487-1493 NNS denotes tumors
T12399 1493-1494 . denotes .
T12400 1495-1501 NN denotes IL-1Ra
T12401 1502-1505 VBZ denotes has
T12402 1506-1510 VBN denotes been
T12403 1511-1516 VBN denotes shown
T12404 1517-1519 TO denotes to
T12405 1520-1527 VB denotes inhibit
T12406 1528-1533 NN denotes tumor
T12407 1534-1545 NN denotes progression
T12408 1546-1548 IN denotes in
T12409 1549-1557 NN denotes prostate
T12410 1557-1558 , denotes ,
T12411 1559-1565 NN denotes breast
T12412 1565-1566 , denotes ,
T12413 1567-1570 CC denotes and
T12414 1571-1575 NN denotes skin
T12415 1576-1582 NN denotes cancer
T12416 1583-1584 NNP denotes [
T12417 1584-1586 CD denotes 14
T12418 1586-1587 NNP denotes ]
T12419 1587-1588 , denotes ,
T12420 1589-1590 NNP denotes [
T12421 1590-1592 CD denotes 15
T12422 1592-1593 NNP denotes ]
T12423 1593-1594 , denotes ,
T12424 1595-1596 NNP denotes [
T12425 1596-1598 CD denotes 16
T12426 1598-1599 NNP denotes ]
T12427 1599-1600 . denotes .
T12428 1601-1614 JJ denotes Intracellular
T12429 1615-1621 NN denotes IL-1Ra
T12430 1622-1623 -LRB- denotes (
T12431 1623-1631 NN denotes icIL-1Ra
T12432 1631-1632 -RRB- denotes )
T12433 1633-1641 VBZ denotes inhibits
T12434 1642-1646 NNP denotes IL-6
T12435 1647-1650 CC denotes and
T12436 1651-1655 JJ denotes IL-8
T12437 1656-1666 NN denotes production
T12438 1667-1669 IN denotes in
T12439 1670-1676 JJ denotes Caco-2
T12440 1677-1682 NNS denotes cells
T12441 1683-1685 IN denotes by
T12442 1686-1694 VBG denotes blocking
T12443 1695-1700 JJ denotes NF-κB
T12444 1701-1709 NNS denotes pathways
T12445 1710-1711 NNP denotes [
T12446 1711-1713 CD denotes 37
T12447 1713-1714 NNP denotes ]
T12448 1714-1715 . denotes .
T12449 1716-1718 PRP denotes We
T12450 1719-1724 VBD denotes found
T12451 1725-1729 IN denotes that
T12452 1730-1733 DT denotes the
T12453 1734-1740 NNS denotes levels
T12454 1741-1743 IN denotes of
T12455 1744-1750 NN denotes IL-1Ra
T12456 1751-1755 VBD denotes were
T12457 1756-1769 RB denotes significantly
T12458 1770-1778 VBN denotes elevated
T12459 1779-1781 IN denotes in
T12460 1782-1785 DT denotes the
T12461 1786-1791 NN denotes tumor
T12462 1792-1799 NNS denotes tissues
T12463 1800-1802 IN denotes of
T12464 1803-1807 CD denotes CCR5
T12465 1807-1808 CD denotes −
T12466 1808-1809 NN denotes /
T12467 1809-1810 NN denotes −
T12468 1811-1815 NNS denotes mice
T12469 1816-1826 VBN denotes inoculated
T12470 1827-1831 IN denotes with
T12471 1832-1835 NNP denotes B16
T12472 1836-1844 NN denotes melanoma
T12473 1845-1850 NNS denotes cells
T12474 1850-1851 . denotes .
T12475 1852-1857 VBN denotes Taken
T12476 1858-1866 RB denotes together
T12477 1866-1867 , denotes ,
T12478 1868-1873 DT denotes these
T12479 1874-1878 NNS denotes data
T12480 1879-1887 VBP denotes indicate
T12481 1888-1894 NN denotes IL-1Ra
T12482 1895-1900 MD denotes could
T12483 1901-1903 VB denotes be
T12484 1904-1914 RB denotes critically
T12485 1915-1923 VBN denotes involved
T12486 1924-1926 IN denotes in
T12487 1927-1930 DT denotes the
T12488 1931-1936 NN denotes tumor
T12489 1937-1943 NN denotes growth
T12490 1944-1954 NN denotes inhibition
T12491 1955-1957 IN denotes of
T12492 1958-1962 CD denotes CCR5
T12493 1962-1963 CD denotes −
T12494 1963-1964 NN denotes /
T12495 1964-1965 NN denotes −
T12496 1966-1970 NNS denotes mice
T12497 1971-1978 IN denotes through
T12498 1979-1982 DT denotes the
T12499 1983-1995 NN denotes inactivation
T12500 1996-1998 IN denotes of
T12501 1999-2004 NN denotes NF-κB
T12502 2005-2007 IN denotes in
T12503 2008-2011 DT denotes the
T12504 2012-2019 JJ denotes present
T12505 2020-2025 NN denotes study
T12506 2025-2026 . denotes .
R7990 T12135 T12136 amod Numerous,studies
R7992 T12136 T12137 nsubj studies,showed
R7993 T12137 T12137 ROOT showed,showed
R7995 T12138 T12140 mark that,affect
R7996 T12139 T12140 nsubj cytokine,affect
R7997 T12140 T12137 ccomp affect,showed
R7999 T12141 T12142 compound tumor,growth
R8000 T12142 T12140 dobj growth,affect
R8001 T12143 T12140 prep by,affect
R8003 T12144 T12143 pcomp regulating,by
R8004 T12145 T12144 dobj NF-κB,regulating
R8006 T12146 T12137 punct .,showed
R8007 T12147 T12148 amod Inflammatory,cytokines
R8008 T12148 T12157 nsubj cytokines,activate
R8010 T12149 T12148 punct ",",cytokines
R8011 T12150 T12148 prep including,cytokines
R8013 T12151 T12150 pobj IL-1,including
R8014 T12152 T12151 punct ",",IL-1
R8015 T12153 T12151 conj IL-6,IL-1
R8017 T12154 T12153 cc and,IL-6
R8018 T12155 T12153 conj IL-8,IL-6
R8019 T12156 T12148 punct ",",cytokines
R8021 T12157 T12157 ROOT activate,activate
R8022 T12158 T12159 amod NF-κB,pathways
R8023 T12159 T12157 dobj pathways,activate
R8025 T12160 T12159 prep in,pathways
R8026 T12161 T12162 compound tumor,cells
R8027 T12162 T12160 pobj cells,in
R8029 T12163 T12165 nmod [,]
R8030 T12164 T12165 nummod 41,]
R8032 T12165 T12159 conj ],pathways
R8033 T12166 T12157 punct .,activate
R8034 T12167 T12175 det The,known
R8036 T12168 T12175 nsubjpass interleukin,known
R8037 T12169 T12168 nummod 10,interleukin
R8038 T12170 T12168 punct (,interleukin
R8040 T12171 T12168 appos IL-10,interleukin
R8042 T12172 T12168 punct ),interleukin
R8043 T12173 T12175 auxpass is,known
R8044 T12174 T12175 advmod well,known
R8046 T12175 T12175 ROOT known,known
R8047 T12176 T12175 prep as,known
R8048 T12177 T12179 det an,factor
R8050 T12178 T12179 amod anti-tumor,factor
R8051 T12179 T12176 pobj factor,as
R8053 T12180 T12182 advmod as,as
R8054 T12181 T12182 advmod well,as
R8055 T12182 T12179 cc as,factor
R8057 T12183 T12185 det an,factor
R8058 T12184 T12185 amod anti-inflammatory,factor
R8060 T12185 T12179 conj factor,factor
R8061 T12186 T12188 nmod [,]
R8062 T12187 T12188 nummod 42,]
R8064 T12188 T12185 appos ],factor
R8065 T12189 T12188 punct ",",]
R8066 T12190 T12192 nmod [,]
R8068 T12191 T12192 nummod 43,]
R8069 T12192 T12188 appos ],]
R8070 T12193 T12175 punct .,known
R8072 T12194 T12195 amod IL-10,inhibits
R8073 T12195 T12197 nsubj inhibits,activated
R8074 T12196 T12197 advmod constitutively,activated
R8076 T12197 T12197 ROOT activated,activated
R8077 T12198 T12199 compound NF-κB,both
R8078 T12199 T12200 preconj both,in
R8080 T12200 T12197 prep in,activated
R8081 T12201 T12204 amod vitro,]
R8082 T12202 T12204 nmod [,]
R8084 T12203 T12204 nummod 44,]
R8085 T12204 T12200 pobj ],in
R8087 T12205 T12200 cc and,in
R8088 T12206 T12200 conj in,in
R8089 T12207 T12208 compound vivo,[
R8090 T12208 T12206 pobj [,in
R8091 T12209 T12210 nummod 45,]
R8092 T12210 T12208 appos ],[
R8094 T12211 T12197 punct .,activated
R8097 T12212 T12218 nsubj Inhibition,contributes
R8099 T12213 T12212 prep of,Inhibition
R8101 T12214 T12213 pobj NF-κB,of
R8102 T12215 T12212 prep by,Inhibition
R8103 T12216 T12217 det the,IL-10
R8104 T12217 T12215 pobj IL-10,by
R8105 T12218 T12218 ROOT contributes,contributes
R8107 T12219 T12218 prep to,contributes
R8108 T12220 T12222 det the,effects
R8109 T12221 T12222 amod anti-tumor,effects
R8111 T12222 T12219 pobj effects,to
R8112 T12223 T12222 prep through,effects
R8113 T12224 T12225 det the,activation
R8115 T12225 T12223 pobj activation,through
R8116 T12226 T12225 prep of,activation
R8117 T12227 T12226 pobj caspase-3,of
R8118 T12309 T12310 aux to,regulate
R8119 T12228 T12227 cc and,caspase-3
R8120 T12229 T12227 conj apoptosis,caspase-3
R8121 T12230 T12225 prep in,activation
R8122 T12231 T12232 amod Colon26-bearing,mice
R8123 T12232 T12230 pobj mice,in
R8124 T12310 T12308 xcomp regulate,is
R8125 T12233 T12235 nmod [,]
R8126 T12234 T12235 nummod 43,]
R8127 T12235 T12225 appos ],activation
R8128 T12311 T12313 det the,effects
R8129 T12236 T12218 punct .,contributes
R8130 T12237 T12242 advmod Similarly,demonstrated
R8131 T12238 T12242 punct ",",demonstrated
R8132 T12312 T12313 amod pleiotropic,effects
R8133 T12239 T12240 amod several,studies
R8134 T12240 T12242 nsubj studies,demonstrated
R8135 T12241 T12242 aux have,demonstrated
R8136 T12313 T12310 dobj effects,regulate
R8137 T12242 T12242 ROOT demonstrated,demonstrated
R8138 T12243 T12244 det the,ability
R8139 T12244 T12242 dobj ability,demonstrated
R8140 T12245 T12244 prep of,ability
R8141 T12246 T12245 pobj IL-1Ra,of
R8142 T12247 T12248 aux to,abrogate
R8143 T12314 T12313 prep of,effects
R8144 T12248 T12244 acl abrogate,ability
R8145 T12249 T12251 det the,effects
R8146 T12315 T12314 pobj IL-1,of
R8147 T12316 T12310 prep by,regulate
R8148 T12250 T12251 amod proinflammatory,effects
R8149 T12317 T12318 advmod competitively,blocking
R8150 T12251 T12248 dobj effects,abrogate
R8151 T12252 T12251 prep of,effects
R8152 T12318 T12316 pcomp blocking,by
R8153 T12253 T12254 compound IL-1,[
R8154 T12254 T12252 pobj [,of
R8155 T12255 T12256 nummod 46,]
R8156 T12319 T12320 poss its,functions
R8157 T12256 T12251 conj ],effects
R8158 T12257 T12242 punct .,demonstrated
R8159 T12258 T12261 nsubjpass It,reported
R8160 T12320 T12318 dobj functions,blocking
R8161 T12259 T12261 aux has,reported
R8162 T12260 T12261 auxpass been,reported
R8163 T12321 T12323 nmod [,]
R8164 T12261 T12261 ROOT reported,reported
R8165 T12262 T12264 mark that,induces
R8166 T12263 T12264 nsubj IL-1,induces
R8167 T12322 T12323 nummod 47,]
R8168 T12264 T12261 ccomp induces,reported
R8169 T12265 T12266 det the,activation
R8170 T12266 T12264 dobj activation,induces
R8171 T12323 T12318 dobj ],blocking
R8172 T12267 T12266 prep of,activation
R8173 T12268 T12267 pobj NF-κB,of
R8174 T12269 T12266 prep in,activation
R8175 T12324 T12301 punct .,indicate
R8176 T12270 T12271 amod several,cancers
R8177 T12271 T12269 pobj cancers,in
R8178 T12272 T12261 punct ",",reported
R8179 T12325 T12326 det The,ability
R8180 T12273 T12261 cc and,reported
R8181 T12274 T12261 conj increases,reported
R8182 T12275 T12276 compound cell,cycle
R8183 T12326 T12334 nsubj ability,is
R8184 T12276 T12277 compound cycle,progression
R8185 T12277 T12274 dobj progression,increases
R8186 T12278 T12274 punct ",",increases
R8187 T12327 T12326 prep of,ability
R8188 T12279 T12274 cc and,increases
R8189 T12280 T12281 det the,suppression
R8190 T12281 T12274 conj suppression,increases
R8191 T12282 T12281 prep of,suppression
R8192 T12283 T12285 amod apoptotic,death
R8193 T12284 T12285 compound cell,death
R8194 T12328 T12327 pobj IL-1,of
R8195 T12285 T12282 pobj death,of
R8196 T12286 T12281 acl leading,suppression
R8197 T12287 T12286 prep to,leading
R8198 T12329 T12330 aux to,induce
R8199 T12288 T12289 compound tumor,promotion
R8200 T12289 T12287 pobj promotion,to
R8201 T12290 T12261 punct .,reported
R8202 T12330 T12326 acl induce,ability
R8203 T12291 T12292 det The,results
R8204 T12292 T12301 nsubj results,indicate
R8205 T12331 T12333 poss its,antagonist
R8206 T12293 T12292 prep of,results
R8207 T12294 T12295 amod various,studies
R8208 T12295 T12293 pobj studies,of
R8209 T12332 T12333 amod own,antagonist
R8210 T12296 T12292 prep over,results
R8211 T12297 T12300 det the,years
R8212 T12298 T12300 amod past,years
R8213 T12333 T12330 dobj antagonist,induce
R8214 T12299 T12300 nummod 10,years
R8215 T12300 T12296 pobj years,over
R8216 T12334 T12334 ROOT is,is
R8217 T12301 T12301 ROOT indicate,indicate
R8218 T12302 T12308 mark that,is
R8219 T12303 T12305 det the,function
R8220 T12335 T12334 prep of,is
R8221 T12304 T12305 amod major,function
R8222 T12305 T12308 nsubj function,is
R8223 T12336 T12335 pobj interest,of
R8224 T12306 T12305 prep of,function
R8225 T12307 T12306 pobj IL-1Ra,of
R8226 T12308 T12301 ccomp is,indicate
R8227 T12337 T12336 prep in,interest
R8228 T12338 T12337 pcomp understanding,in
R8229 T12339 T12340 det the,regulation
R8230 T12406 T12407 compound tumor,progression
R8231 T12407 T12405 dobj progression,inhibit
R8232 T12340 T12338 dobj regulation,understanding
R8233 T12408 T12407 prep in,progression
R8234 T12341 T12340 cc and,regulation
R8235 T12409 T12408 pobj prostate,in
R8236 T12410 T12409 punct ",",prostate
R8237 T12342 T12340 conj dysregulation,regulation
R8238 T12411 T12409 conj breast,prostate
R8239 T12412 T12411 punct ",",breast
R8240 T12413 T12411 cc and,breast
R8241 T12414 T12415 compound skin,cancer
R8242 T12415 T12411 conj cancer,breast
R8243 T12416 T12418 nmod [,]
R8244 T12343 T12340 prep of,regulation
R8245 T12417 T12418 nummod 14,]
R8246 T12418 T12407 appos ],progression
R8247 T12344 T12345 amod IL-1,signaling
R8248 T12419 T12418 punct ",",]
R8249 T12420 T12422 nmod [,]
R8250 T12421 T12422 nummod 15,]
R8251 T12345 T12343 pobj signaling,of
R8252 T12422 T12418 conj ],]
R8253 T12423 T12422 punct ",",]
R8254 T12346 T12340 prep in,regulation
R8255 T12424 T12422 conj [,]
R8256 T12425 T12426 nummod 16,]
R8257 T12426 T12422 conj ],]
R8258 T12427 T12403 punct .,shown
R8259 T12347 T12350 amod normal,tissue
R8260 T12428 T12429 amod Intracellular,IL-1Ra
R8261 T12429 T12433 nsubj IL-1Ra,inhibits
R8262 T12430 T12431 punct (,icIL-1Ra
R8263 T12348 T12347 cc and,normal
R8264 T12431 T12429 appos icIL-1Ra,IL-1Ra
R8265 T12432 T12431 punct ),icIL-1Ra
R8266 T12433 T12433 ROOT inhibits,inhibits
R8267 T12434 T12433 dobj IL-6,inhibits
R8268 T12349 T12347 conj diseased,normal
R8269 T12435 T12434 cc and,IL-6
R8270 T12436 T12437 amod IL-8,production
R8271 T12437 T12434 conj production,IL-6
R8272 T12350 T12346 pobj tissue,in
R8273 T12438 T12437 prep in,production
R8274 T12439 T12440 amod Caco-2,cells
R8275 T12440 T12438 pobj cells,in
R8276 T12351 T12334 punct .,is
R8277 T12441 T12433 prep by,inhibits
R8278 T12442 T12441 pcomp blocking,by
R8279 T12443 T12444 amod NF-κB,pathways
R8280 T12352 T12357 nsubj Up-regulation,represents
R8281 T12444 T12442 dobj pathways,blocking
R8282 T12445 T12447 nmod [,]
R8283 T12446 T12447 nummod 37,]
R8284 T12353 T12352 prep of,Up-regulation
R8285 T12447 T12442 dobj ],blocking
R8286 T12448 T12433 punct .,inhibits
R8287 T12449 T12450 nsubj We,found
R8288 T12354 T12356 det the,antagonist
R8289 T12450 T12450 ROOT found,found
R8290 T12451 T12458 mark that,elevated
R8291 T12452 T12453 det the,levels
R8292 T12453 T12458 nsubjpass levels,elevated
R8293 T12454 T12453 prep of,levels
R8294 T12455 T12454 pobj IL-1Ra,of
R8295 T12355 T12356 compound receptor,antagonist
R8296 T12456 T12458 auxpass were,elevated
R8297 T12457 T12458 advmod significantly,elevated
R8298 T12458 T12450 ccomp elevated,found
R8299 T12459 T12458 prep in,elevated
R8300 T12356 T12353 pobj antagonist,of
R8301 T12460 T12462 det the,tissues
R8302 T12461 T12462 compound tumor,tissues
R8303 T12462 T12459 pobj tissues,in
R8304 T12357 T12357 ROOT represents,represents
R8305 T12463 T12462 prep of,tissues
R8306 T12464 T12468 nummod CCR5,mice
R8307 T12465 T12468 nummod −,mice
R8308 T12358 T12359 det a,mechanism
R8309 T12466 T12468 compound /,mice
R8310 T12467 T12468 compound −,mice
R8311 T12468 T12463 pobj mice,of
R8312 T12359 T12357 dobj mechanism,represents
R8313 T12469 T12468 acl inoculated,mice
R8314 T12470 T12469 prep with,inoculated
R8315 T12471 T12473 compound B16,cells
R8316 T12360 T12359 prep for,mechanism
R8317 T12472 T12473 compound melanoma,cells
R8318 T12473 T12470 pobj cells,with
R8319 T12474 T12450 punct .,found
R8320 T12361 T12360 pcomp turning,for
R8321 T12475 T12480 advcl Taken,indicate
R8322 T12476 T12475 advmod together,Taken
R8323 T12477 T12480 punct ",",indicate
R8324 T12362 T12361 prt off,turning
R8325 T12478 T12479 det these,data
R8326 T12479 T12480 nsubj data,indicate
R8327 T12363 T12361 dobj IL-1,turning
R8328 T12480 T12480 ROOT indicate,indicate
R8329 T12481 T12485 nsubjpass IL-1Ra,involved
R8330 T12482 T12485 aux could,involved
R8331 T12364 T12361 conj signaling,turning
R8332 T12483 T12485 auxpass be,involved
R8333 T12365 T12364 cc and,signaling
R8334 T12484 T12485 advmod critically,involved
R8335 T12366 T12364 conj creating,signaling
R8336 T12485 T12480 ccomp involved,indicate
R8337 T12486 T12485 prep in,involved
R8338 T12367 T12369 det a,state
R8339 T12368 T12369 amod temporary,state
R8340 T12487 T12490 det the,inhibition
R8341 T12488 T12489 compound tumor,growth
R8342 T12489 T12490 compound growth,inhibition
R8343 T12369 T12366 dobj state,creating
R8344 T12490 T12486 pobj inhibition,in
R8345 T12491 T12490 prep of,inhibition
R8346 T12492 T12496 nummod CCR5,mice
R8347 T12370 T12369 prep of,state
R8348 T12493 T12496 nummod −,mice
R8349 T12494 T12496 nmod /,mice
R8350 T12371 T12370 pobj refractoriness,of
R8351 T12495 T12496 compound −,mice
R8352 T12496 T12491 pobj mice,of
R8353 T12497 T12485 prep through,involved
R8354 T12372 T12357 punct .,represents
R8355 T12498 T12499 det the,inactivation
R8356 T12499 T12497 pobj inactivation,through
R8357 T12500 T12499 prep of,inactivation
R8358 T12501 T12500 pobj NF-κB,of
R8359 T12373 T12375 det The,expression
R8360 T12502 T12499 prep in,inactivation
R8361 T12374 T12375 amod elevated,expression
R8362 T12375 T12387 nsubj expression,suggests
R8363 T12376 T12375 prep of,expression
R8364 T12377 T12376 pobj IL-1Ra,of
R8365 T12378 T12375 punct ",",expression
R8366 T12503 T12505 det the,study
R8367 T12504 T12505 amod present,study
R8368 T12505 T12502 pobj study,in
R8369 T12379 T12375 prep without,expression
R8370 T12506 T12480 punct .,indicate
R8372 T12380 T12381 det any,change
R8376 T12381 T12379 pobj change,without
R8380 T12382 T12381 prep of,change
R8383 T12383 T12382 pobj IL-1,of
R8387 T12384 T12381 prep in,change
R8394 T12385 T12384 pobj tumors,in
R8398 T12386 T12387 punct ",",suggests
R8402 T12387 T12387 ROOT suggests,suggests
R8406 T12388 T12394 mark that,dysregulated
R8411 T12389 T12391 det the,system
R8414 T12390 T12391 amod IL-1-signaling,system
R8418 T12391 T12394 nsubjpass system,dysregulated
R8422 T12392 T12394 aux may,dysregulated
R8425 T12393 T12394 auxpass be,dysregulated
R8429 T12394 T12387 ccomp dysregulated,suggests
R8433 T12395 T12394 agent by,dysregulated
R8437 T12396 T12395 pobj IL-1Ra,by
R8444 T12397 T12394 prep in,dysregulated
R8448 T12398 T12397 pobj tumors,in
R8449 T12399 T12387 punct .,suggests
R8451 T12400 T12403 nsubjpass IL-1Ra,shown
R8455 T12401 T12403 aux has,shown
R8458 T12402 T12403 auxpass been,shown
R8462 T12403 T12403 ROOT shown,shown
R8465 T12404 T12405 aux to,inhibit
R8469 T12405 T12403 xcomp inhibit,shown