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PMC:3342329 JSONTXT 30 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T820 0-10 NN denotes Deficiency
T821 11-13 IN denotes of
T822 14-17 NNP denotes C-C
T823 18-27 NNP denotes Chemokine
T824 28-36 NNP denotes Receptor
T825 37-38 CD denotes 5
T826 39-49 NNPS denotes Suppresses
T827 50-55 NNP denotes Tumor
T828 56-84 NNP denotes Development via Inactivation
T829 85-87 IN denotes of
T830 88-90 NNP denotes NF
T831 90-91 : denotes -
T832 91-92 . denotes κ
T833 92-93 NNP denotes B
T834 94-97 CC denotes and
T835 98-110 NNP denotes Upregulation
T836 111-113 IN denotes of
T837 114-120 NNP denotes IL-1Ra
T838 121-123 IN denotes in
T839 124-132 NNP denotes Melanoma
T840 133-138 NNP denotes Model
T841 195-197 TO denotes To
T842 198-206 VB denotes evaluate
T843 207-210 DT denotes the
T844 211-220 NN denotes relevance
T845 221-223 IN denotes of
T846 224-227 NNP denotes C-C
T847 228-237 NN denotes chemokine
T848 238-246 NN denotes receptor
T849 247-251 NN denotes type
T850 252-253 CD denotes 5
T851 254-255 -LRB- denotes (
T852 255-259 NNS denotes CCR5
T853 259-260 -RRB- denotes )
T854 261-271 NN denotes expression
T855 272-275 CC denotes and
T856 276-281 NN denotes tumor
T857 282-293 NN denotes development
T858 293-294 , denotes ,
T859 295-297 PRP denotes we
T860 298-306 VBD denotes compared
T861 307-315 NN denotes melanoma
T862 316-322 NN denotes growth
T863 323-325 IN denotes in
T864 326-330 CD denotes CCR5
T865 331-339 NN denotes knockout
T866 340-341 -LRB- denotes (
T867 341-345 CD denotes CCR5
T868 345-346 CD denotes −
T869 346-347 NN denotes /
T870 347-348 NN denotes −
T871 348-349 -RRB- denotes )
T872 350-354 NNS denotes mice
T873 355-358 CC denotes and
T874 359-363 JJ denotes wild
T875 364-368 NN denotes type
T876 369-370 -LRB- denotes (
T877 370-374 CD denotes CCR5
T878 374-375 CD denotes +
T879 375-376 NN denotes /
T880 376-377 NN denotes +
T881 377-378 -RRB- denotes )
T882 379-383 NNS denotes mice
T883 383-384 . denotes .
T884 385-389 CD denotes CCR5
T885 389-390 CD denotes −
T886 390-391 NN denotes /
T887 391-392 NN denotes −
T888 393-397 NNS denotes mice
T889 398-404 VBD denotes showed
T890 405-412 VBN denotes reduced
T891 413-418 NN denotes tumor
T892 419-425 NN denotes volume
T893 425-426 , denotes ,
T894 427-432 NN denotes tumor
T895 433-439 NN denotes weight
T896 439-440 , denotes ,
T897 441-444 CC denotes and
T898 445-454 VBD denotes increased
T899 455-463 NN denotes survival
T900 464-468 NN denotes rate
T901 469-473 WRB denotes when
T902 474-482 VBN denotes compared
T903 483-485 TO denotes to
T904 486-490 CD denotes CCR5
T905 490-491 CD denotes +
T906 491-492 NN denotes /
T907 492-493 NN denotes +
T908 494-498 NNS denotes mice
T909 498-499 . denotes .
T910 500-502 PRP denotes We
T911 503-515 VBD denotes investigated
T912 516-519 DT denotes the
T913 520-530 NN denotes activation
T914 531-533 IN denotes of
T915 534-539 NN denotes NF-κB
T916 540-545 IN denotes since
T917 546-548 PRP denotes it
T918 549-551 VBZ denotes is
T919 552-554 DT denotes an
T920 555-565 VBN denotes implicated
T921 566-579 NN denotes transcription
T922 580-586 NN denotes factor
T923 587-589 IN denotes in
T924 590-593 DT denotes the
T925 594-604 NN denotes regulation
T926 605-607 IN denotes of
T927 608-613 NNS denotes genes
T928 614-623 VBG denotes involving
T929 624-628 NN denotes cell
T930 629-635 NN denotes growth
T931 635-636 , denotes ,
T932 637-646 NN denotes apoptosis
T933 646-647 , denotes ,
T934 648-651 CC denotes and
T935 652-657 NN denotes tumor
T936 658-664 NN denotes growth
T937 664-665 . denotes .
T938 666-677 JJ denotes Significant
T939 678-688 NN denotes inhibition
T940 689-691 IN denotes of
T941 692-695 NNP denotes DNA
T942 696-703 JJ denotes binding
T943 704-712 NN denotes activity
T944 713-715 IN denotes of
T945 716-721 NNP denotes NF-κB
T946 721-722 , denotes ,
T947 723-726 CC denotes and
T948 727-740 NN denotes translocation
T949 741-743 IN denotes of
T950 744-747 CD denotes p50
T951 748-751 CC denotes and
T952 752-755 CD denotes p65
T953 756-760 IN denotes into
T954 761-764 DT denotes the
T955 765-772 NN denotes nucleus
T956 773-780 IN denotes through
T957 781-784 DT denotes the
T958 785-795 NN denotes inhibition
T959 796-798 IN denotes of
T960 799-814 NN denotes phosphorylation
T961 815-817 IN denotes of
T962 818-821 NNP denotes IκB
T963 822-825 VBD denotes was
T964 826-831 VBN denotes found
T965 832-834 IN denotes in
T966 835-838 DT denotes the
T967 839-847 NN denotes melanoma
T968 848-855 NNS denotes tissues
T969 856-858 IN denotes of
T970 859-863 CD denotes CCR5
T971 863-864 CD denotes −
T972 864-865 NN denotes /
T973 865-866 NN denotes −
T974 867-871 NNS denotes mice
T975 872-880 VBN denotes compared
T976 881-883 TO denotes to
T977 884-892 VB denotes melanoma
T978 893-900 NNS denotes tissues
T979 901-903 IN denotes of
T980 904-908 CD denotes CCR5
T981 908-909 CD denotes +
T982 909-910 NN denotes /
T983 910-911 NN denotes +
T984 912-916 NNS denotes mice
T985 916-917 . denotes .
T986 918-923 JJ denotes NF-κB
T987 924-930 NN denotes target
T988 931-940 JJ denotes apoptotic
T989 941-948 NN denotes protein
T990 949-959 NN denotes expression
T991 959-960 , denotes ,
T992 961-965 JJ denotes such
T993 966-968 IN denotes as
T994 969-976 JJ denotes cleaved
T995 977-986 JJ denotes caspase-3
T996 986-987 , denotes ,
T997 988-995 JJ denotes cleaved
T998 996-1000 NNP denotes PARP
T999 1000-1001 , denotes ,
T1000 1002-1005 CC denotes and
T1001 1006-1009 NNP denotes Bax
T1002 1009-1010 , denotes ,
T1003 1011-1014 VBD denotes was
T1004 1015-1023 VBN denotes elevated
T1005 1023-1024 , denotes ,
T1006 1025-1032 IN denotes whereas
T1007 1033-1036 DT denotes the
T1008 1037-1045 NN denotes survival
T1009 1046-1053 NN denotes protein
T1010 1054-1064 NN denotes expression
T1011 1065-1071 NNS denotes levels
T1012 1071-1072 , denotes ,
T1013 1073-1077 JJ denotes such
T1014 1078-1080 IN denotes as
T1015 1081-1086 NN denotes Bcl-2
T1016 1086-1087 , denotes ,
T1017 1088-1094 NNP denotes C-IAP1
T1018 1094-1095 , denotes ,
T1019 1096-1099 VBD denotes was
T1020 1100-1109 VBN denotes decreased
T1021 1110-1112 IN denotes in
T1022 1113-1116 DT denotes the
T1023 1117-1125 NN denotes melanoma
T1024 1126-1133 NNS denotes tissues
T1025 1134-1136 IN denotes of
T1026 1137-1141 CD denotes CCR5
T1027 1141-1142 CD denotes −
T1028 1142-1143 NN denotes /
T1029 1143-1144 NN denotes −
T1030 1145-1149 NNS denotes mice
T1031 1149-1150 . denotes .
T1032 1151-1164 RB denotes Interestingly
T1033 1164-1165 , denotes ,
T1034 1166-1168 PRP denotes we
T1035 1169-1174 VBD denotes found
T1036 1175-1179 IN denotes that
T1037 1180-1183 DT denotes the
T1038 1184-1189 NN denotes level
T1039 1190-1192 IN denotes of
T1040 1193-1199 NN denotes IL-1Ra
T1041 1199-1200 , denotes ,
T1042 1201-1202 DT denotes a
T1043 1203-1208 NN denotes tumor
T1044 1209-1215 NN denotes growth
T1045 1216-1227 JJ denotes suppressive
T1046 1228-1236 NN denotes cytokine
T1047 1236-1237 , denotes ,
T1048 1238-1241 VBD denotes was
T1049 1242-1255 RB denotes significantly
T1050 1256-1264 VBN denotes elevated
T1051 1265-1267 IN denotes in
T1052 1268-1273 NN denotes tumor
T1053 1274-1280 NN denotes tissue
T1054 1281-1284 CC denotes and
T1055 1285-1291 NN denotes spleen
T1056 1292-1294 IN denotes of
T1057 1295-1299 CD denotes CCR5
T1058 1299-1300 CD denotes −
T1059 1300-1301 NN denotes /
T1060 1301-1302 NN denotes −
T1061 1303-1307 NNS denotes mice
T1062 1308-1316 VBN denotes compared
T1063 1317-1319 TO denotes to
T1064 1320-1323 DT denotes the
T1065 1324-1329 NN denotes level
T1066 1330-1332 IN denotes in
T1067 1333-1337 CD denotes CCR5
T1068 1337-1338 CD denotes +
T1069 1338-1339 NN denotes /
T1070 1339-1340 NN denotes +
T1071 1341-1345 NNS denotes mice
T1072 1345-1346 . denotes .
T1073 1347-1355 RB denotes Moreover
T1074 1355-1356 , denotes ,
T1075 1357-1369 NN denotes infiltration
T1076 1370-1372 IN denotes of
T1077 1373-1376 CD denotes CD8
T1078 1376-1377 CD denotes +
T1079 1378-1387 JJ denotes cytotoxic
T1080 1388-1389 NNP denotes T
T1081 1390-1394 NN denotes cell
T1082 1395-1398 CC denotes and
T1083 1399-1403 NNP denotes CD57
T1084 1403-1404 VBP denotes +
T1085 1405-1412 JJ denotes natural
T1086 1413-1419 NN denotes killer
T1087 1420-1425 NNS denotes cells
T1088 1426-1429 VBD denotes was
T1089 1430-1443 RB denotes significantly
T1090 1444-1453 VBN denotes increased
T1091 1454-1456 IN denotes in
T1092 1457-1465 NN denotes melanoma
T1093 1466-1471 NN denotes tumor
T1094 1472-1475 CC denotes and
T1095 1476-1482 NN denotes spleen
T1096 1483-1489 NN denotes tissue
T1097 1490-1492 IN denotes of
T1098 1493-1497 CD denotes CCR5
T1099 1497-1498 CD denotes −
T1100 1498-1499 NN denotes /
T1101 1499-1500 NN denotes −
T1102 1501-1505 NNS denotes mice
T1103 1506-1514 VBN denotes compared
T1104 1515-1517 TO denotes to
T1105 1518-1522 DT denotes that
T1106 1523-1525 IN denotes of
T1107 1526-1530 CD denotes CCR5
T1108 1530-1531 CD denotes +
T1109 1531-1532 NN denotes /
T1110 1532-1533 NN denotes +
T1111 1534-1538 NNS denotes mice
T1112 1538-1539 . denotes .
T1113 1540-1549 RB denotes Therefore
T1114 1549-1550 , denotes ,
T1115 1551-1556 DT denotes these
T1116 1557-1564 NNS denotes results
T1117 1565-1571 VBD denotes showed
T1118 1572-1576 IN denotes that
T1119 1577-1581 CD denotes CCR5
T1120 1582-1592 NN denotes deficiency
T1121 1593-1599 VBD denotes caused
T1122 1600-1609 JJ denotes apoptotic
T1123 1610-1614 NN denotes cell
T1124 1615-1620 NN denotes death
T1125 1621-1623 IN denotes of
T1126 1624-1632 NN denotes melanoma
T1127 1633-1640 IN denotes through
T1128 1641-1651 NN denotes inhibition
T1129 1652-1654 IN denotes of
T1130 1655-1660 NNP denotes NF-κB
T1131 1661-1664 CC denotes and
T1132 1665-1677 NN denotes upregulation
T1133 1678-1680 IN denotes of
T1134 1681-1687 NN denotes IL-1Ra
T1135 1687-1688 . denotes .
T3164 1703-1713 NNS denotes Chemokines
T3165 1714-1717 VBP denotes are
T3166 1718-1723 JJ denotes small
T3167 1724-1731 JJ denotes soluble
T3168 1732-1741 NNS denotes molecules
T3169 1742-1746 WDT denotes that
T3170 1747-1750 VBP denotes are
T3171 1751-1755 RBS denotes best
T3172 1756-1761 VBN denotes known
T3173 1762-1765 IN denotes for
T3174 1766-1771 PRP$ denotes their
T3175 1772-1778 JJ denotes potent
T3176 1779-1786 NN denotes ability
T3177 1787-1789 TO denotes to
T3178 1790-1796 VB denotes induce
T3179 1797-1803 NN denotes cancer
T3180 1804-1808 NN denotes cell
T3181 1809-1815 NN denotes growth
T3182 1816-1818 IN denotes by
T3183 1819-1831 NN denotes inflammation
T3184 1831-1832 . denotes .
T3185 1833-1837 JJ denotes Many
T3186 1838-1843 NNS denotes types
T3187 1844-1846 IN denotes of
T3188 1847-1853 NN denotes cancer
T3189 1854-1859 NNS denotes cells
T3190 1860-1867 VBP denotes express
T3191 1868-1878 NNS denotes chemokines
T3192 1879-1882 CC denotes and
T3193 1883-1892 NN denotes chemokine
T3194 1893-1902 NNS denotes receptors
T3195 1903-1904 VBP denotes [
T3196 1904-1905 CD denotes 1
T3197 1905-1906 NNP denotes ]
T3198 1906-1907 . denotes .
T3199 1908-1911 DT denotes The
T3200 1912-1923 VBN denotes accumulated
T3201 1924-1932 NN denotes evidence
T3202 1933-1942 VBZ denotes indicates
T3203 1943-1947 IN denotes that
T3204 1948-1951 DT denotes the
T3205 1952-1961 NN denotes chemokine
T3206 1962-1963 -LRB- denotes (
T3207 1963-1966 JJ denotes C-C
T3208 1967-1972 NN denotes motif
T3209 1972-1973 -RRB- denotes )
T3210 1974-1980 NN denotes ligand
T3211 1981-1982 CD denotes 5
T3212 1983-1984 -LRB- denotes (
T3213 1984-1988 NNS denotes CCL5
T3214 1988-1989 -RRB- denotes )
T3215 1990-1993 CC denotes and
T3216 1994-1997 NNP denotes C-C
T3217 1998-2007 NN denotes chemokine
T3218 2008-2016 NN denotes receptor
T3219 2017-2018 -LRB- denotes (
T3220 2018-2022 NNS denotes CCR5
T3221 2022-2023 -RRB- denotes )
T3222 2023-2024 , denotes ,
T3223 2025-2030 WDT denotes which
T3224 2031-2034 VBP denotes are
T3225 2035-2041 JJ denotes potent
T3226 2042-2053 NN denotes chemotactic
T3227 2054-2061 NNS denotes factors
T3228 2062-2065 IN denotes for
T3229 2066-2078 JJ denotes inflammatory
T3230 2079-2084 NNS denotes cells
T3231 2084-2085 , denotes ,
T3232 2086-2089 MD denotes may
T3233 2090-2092 VB denotes be
T3234 2093-2106 RB denotes significantly
T3235 2107-2115 VBN denotes involved
T3236 2116-2118 IN denotes in
T3237 2119-2122 DT denotes the
T3238 2123-2136 NN denotes proliferation
T3239 2137-2140 CC denotes and
T3240 2141-2151 NN denotes metastasis
T3241 2152-2154 IN denotes of
T3242 2155-2162 JJ denotes several
T3243 2163-2170 NNS denotes cancers
T3244 2170-2171 . denotes .
T3245 2172-2184 NNP denotes Intermediate
T3246 2185-2188 CC denotes and
T3247 2189-2195 JJ denotes strong
T3248 2196-2200 NNS denotes CCR5
T3249 2201-2211 NN denotes expression
T3250 2212-2214 VBZ denotes is
T3251 2215-2228 RB denotes significantly
T3252 2229-2239 VBN denotes associated
T3253 2240-2244 IN denotes with
T3254 2245-2258 JJ denotes nonmetastatic
T3255 2259-2270 NN denotes development
T3256 2271-2273 IN denotes of
T3257 2274-2284 JJ denotes colorectal
T3258 2285-2291 NN denotes cancer
T3259 2292-2293 NN denotes [
T3260 2293-2294 CD denotes 2
T3261 2294-2295 NNP denotes ]
T3262 2295-2296 , denotes ,
T3263 2297-2305 NN denotes melanoma
T3264 2306-2307 NN denotes [
T3265 2307-2308 CD denotes 3
T3266 2308-2309 NNP denotes ]
T3267 2309-2310 , denotes ,
T3268 2311-2319 NN denotes hepatoma
T3269 2320-2321 NN denotes [
T3270 2321-2322 CD denotes 4
T3271 2322-2323 NNP denotes ]
T3272 2323-2324 , denotes ,
T3273 2325-2337 NN denotes glioblastoma
T3274 2337-2338 , denotes ,
T3275 2339-2346 NNP denotes Hodgkin
T3276 2347-2355 NN denotes lymphoma
T3277 2356-2357 NN denotes [
T3278 2357-2358 CD denotes 5
T3279 2358-2359 NNP denotes ]
T3280 2359-2360 , denotes ,
T3281 2361-2363 RB denotes as
T3282 2364-2368 RB denotes well
T3283 2369-2371 IN denotes as
T3284 2372-2376 JJ denotes oral
T3285 2377-2380 CC denotes and
T3286 2381-2389 NN denotes prostate
T3287 2390-2396 NN denotes cancer
T3288 2397-2402 NNS denotes cells
T3289 2403-2404 VBP denotes [
T3290 2404-2405 CD denotes 6
T3291 2405-2406 NNP denotes ]
T3292 2406-2407 . denotes .
T3293 2408-2413 JJ denotes Local
T3294 2414-2424 NN denotes production
T3295 2425-2427 IN denotes of
T3296 2428-2431 DT denotes the
T3297 2432-2436 NNP denotes CCL5
T3298 2437-2439 VBZ denotes is
T3299 2440-2444 RB denotes also
T3300 2445-2454 JJ denotes important
T3301 2455-2457 IN denotes in
T3302 2458-2461 DT denotes the
T3303 2462-2473 NN denotes progression
T3304 2474-2476 IN denotes of
T3305 2477-2483 NN denotes breast
T3306 2484-2490 NN denotes cancer
T3307 2491-2492 NN denotes [
T3308 2492-2493 CD denotes 7
T3309 2493-2494 NNP denotes ]
T3310 2494-2495 , denotes ,
T3311 2496-2499 CC denotes and
T3312 2500-2504 RB denotes also
T3313 2505-2515 VBZ denotes correlates
T3314 2516-2520 IN denotes with
T3315 2521-2525 JJ denotes poor
T3316 2526-2535 NN denotes prognosis
T3317 2536-2537 NN denotes [
T3318 2537-2538 CD denotes 8
T3319 2538-2539 NNP denotes ]
T3320 2539-2540 . denotes .
T3321 2541-2550 RB denotes Meanwhile
T3322 2550-2551 , denotes ,
T3323 2552-2556 NNP denotes CCR5
T3324 2557-2567 NN denotes disruption
T3325 2568-2571 VBZ denotes has
T3326 2572-2576 VBN denotes been
T3327 2577-2589 VBN denotes demonstrated
T3328 2590-2592 TO denotes to
T3329 2593-2600 VB denotes inhibit
T3330 2601-2613 JJ denotes experimental
T3331 2614-2619 NN denotes tumor
T3332 2620-2626 NN denotes growth
T3333 2627-2630 CC denotes and
T3334 2631-2641 NN denotes metastasis
T3335 2642-2644 IN denotes of
T3336 2645-2655 JJ denotes pancreatic
T3337 2656-2662 NN denotes cancer
T3338 2663-2664 NN denotes [
T3339 2664-2665 CD denotes 9
T3340 2665-2666 NNP denotes ]
T3341 2666-2667 . denotes .
T3342 2668-2670 IN denotes In
T3343 2671-2679 NN denotes addition
T3344 2679-2680 , denotes ,
T3345 2681-2685 NN denotes host
T3346 2686-2693 NN denotes absence
T3347 2694-2696 IN denotes of
T3348 2697-2701 CD denotes CCR5
T3349 2702-2713 NNS denotes potentiates
T3350 2714-2717 DT denotes the
T3351 2718-2723 NN denotes delay
T3352 2724-2726 IN denotes of
T3353 2727-2732 NN denotes tumor
T3354 2733-2739 NN denotes growth
T3355 2740-2741 NNP denotes [
T3356 2741-2743 CD denotes 10
T3357 2743-2744 NNP denotes ]
T3358 2744-2745 , denotes ,
T3359 2746-2749 CC denotes and
T3360 2750-2754 NNP denotes CCR5
T3361 2755-2765 NNS denotes inhibitors
T3362 2766-2775 VBD denotes prevented
T3363 2776-2782 NN denotes cancer
T3364 2783-2787 NN denotes cell
T3365 2788-2794 NN denotes growth
T3366 2794-2795 , denotes ,
T3367 2796-2800 JJ denotes such
T3368 2801-2803 IN denotes as
T3369 2804-2812 NN denotes prostate
T3370 2813-2819 NN denotes cancer
T3371 2820-2821 NNP denotes [
T3372 2821-2823 CD denotes 11
T3373 2823-2824 NNP denotes ]
T3374 2824-2825 , denotes ,
T3375 2826-2832 NN denotes breast
T3376 2833-2839 NN denotes cancer
T3377 2839-2840 , denotes ,
T3378 2841-2849 NN denotes hepatoma
T3379 2850-2855 NNS denotes cells
T3380 2856-2857 VBP denotes [
T3381 2857-2858 CD denotes 4
T3382 2858-2859 NNP denotes ]
T3383 2859-2860 , denotes ,
T3384 2861-2864 CC denotes and
T3385 2865-2869 NN denotes lung
T3386 2870-2876 NN denotes cancer
T3387 2877-2878 NNP denotes [
T3388 2878-2880 CD denotes 12
T3389 2880-2881 NNP denotes ]
T3390 2881-2882 . denotes .
T3391 2883-2888 DT denotes These
T3392 2889-2893 NNS denotes data
T3393 2894-2901 VBP denotes suggest
T3394 2902-2906 IN denotes that
T3395 2907-2910 DT denotes the
T3396 2911-2921 NN denotes deficiency
T3397 2922-2924 IN denotes of
T3398 2925-2937 JJ denotes inflammatory
T3399 2938-2947 NN denotes chemokine
T3400 2948-2956 NN denotes receptor
T3401 2957-2961 NNS denotes CCR5
T3402 2962-2965 MD denotes may
T3403 2966-2974 VB denotes function
T3404 2975-2977 IN denotes as
T3405 2978-2979 DT denotes a
T3406 2980-2991 NN denotes suppressive
T3407 2992-3000 NN denotes receptor
T3408 3001-3003 IN denotes in
T3409 3004-3010 NN denotes cancer
T3410 3011-3022 NN denotes progression
T3411 3022-3023 . denotes .
T3412 3024-3031 RB denotes However
T3413 3031-3032 , denotes ,
T3414 3033-3037 JJR denotes more
T3415 3038-3045 NNS denotes studies
T3416 3046-3049 VBP denotes are
T3417 3050-3058 VBN denotes required
T3418 3059-3061 TO denotes to
T3419 3062-3070 VB denotes describe
T3420 3071-3074 WRB denotes how
T3421 3075-3079 JJ denotes CCR5
T3422 3080-3090 NN denotes deficiency
T3423 3091-3095 NNS denotes acts
T3424 3096-3098 IN denotes in
T3425 3099-3102 DT denotes the
T3426 3103-3113 NN denotes inhibition
T3427 3114-3116 IN denotes of
T3428 3117-3122 NN denotes tumor
T3429 3123-3134 NN denotes development
T3430 3134-3135 . denotes .
T3431 3136-3149 NN denotes Interleukin-1
T3432 3150-3158 NN denotes receptor
T3433 3159-3169 NN denotes antagonist
T3434 3170-3171 -LRB- denotes (
T3435 3171-3177 NN denotes IL-1Ra
T3436 3177-3178 -RRB- denotes )
T3437 3178-3179 , denotes ,
T3438 3180-3181 DT denotes a
T3439 3182-3188 NN denotes member
T3440 3189-3191 IN denotes of
T3441 3192-3195 DT denotes the
T3442 3196-3200 NNP denotes IL-1
T3443 3201-3207 NN denotes family
T3444 3207-3208 , denotes ,
T3445 3209-3211 VBZ denotes is
T3446 3212-3213 DT denotes a
T3447 3214-3223 RB denotes naturally
T3448 3224-3233 VBG denotes occurring
T3449 3234-3242 NN denotes cytokine
T3450 3243-3247 WDT denotes that
T3451 3248-3261 RB denotes competitively
T3452 3262-3268 VBZ denotes blocks
T3453 3269-3272 DT denotes the
T3454 3273-3277 NN denotes IL-1
T3455 3278-3286 NN denotes receptor
T3456 3287-3288 NNP denotes [
T3457 3288-3290 CD denotes 13
T3458 3290-3291 NNP denotes ]
T3459 3291-3292 . denotes .
T3460 3293-3300 IN denotes Because
T3461 3301-3307 NN denotes IL-1Ra
T3462 3308-3311 VBZ denotes has
T3463 3312-3316 VBN denotes been
T3464 3317-3322 VBN denotes shown
T3465 3323-3325 TO denotes to
T3466 3326-3333 VB denotes inhibit
T3467 3334-3339 NN denotes tumor
T3468 3340-3351 NN denotes progression
T3469 3352-3354 IN denotes by
T3470 3355-3364 VBG denotes promoting
T3471 3365-3374 JJ denotes antitumor
T3472 3375-3381 JJ denotes immune
T3473 3382-3391 NNS denotes responses
T3474 3392-3395 CC denotes and
T3475 3396-3398 IN denotes by
T3476 3399-3408 VBG denotes enhancing
T3477 3409-3412 DT denotes the
T3478 3413-3421 NN denotes activity
T3479 3422-3424 IN denotes of
T3480 3425-3437 JJ denotes chemotherapy
T3481 3437-3438 , denotes ,
T3482 3439-3447 JJ denotes numerous
T3483 3448-3455 NNS denotes studies
T3484 3456-3460 VBP denotes have
T3485 3461-3469 VBN denotes examined
T3486 3470-3473 DT denotes the
T3487 3474-3481 NN denotes ability
T3488 3482-3484 IN denotes of
T3489 3485-3491 NN denotes IL-1Ra
T3490 3492-3494 TO denotes to
T3491 3495-3500 VB denotes block
T3492 3501-3506 NN denotes tumor
T3493 3507-3518 NN denotes progression
T3494 3518-3519 . denotes .
T3495 3520-3526 NN denotes IL-1Ra
T3496 3527-3537 NN denotes expression
T3497 3538-3541 VBD denotes was
T3498 3542-3549 VBN denotes reduced
T3499 3550-3552 IN denotes in
T3500 3553-3561 NN denotes prostate
T3501 3562-3563 NNP denotes [
T3502 3563-3565 CD denotes 14
T3503 3565-3566 NNP denotes ]
T3504 3566-3567 , denotes ,
T3505 3568-3574 NN denotes breast
T3506 3575-3576 NNP denotes [
T3507 3576-3578 CD denotes 15
T3508 3578-3579 NNP denotes ]
T3509 3579-3580 , denotes ,
T3510 3581-3584 CC denotes and
T3511 3585-3589 NN denotes skin
T3512 3590-3596 NN denotes cancer
T3513 3597-3598 NNP denotes [
T3514 3598-3600 CD denotes 16
T3515 3600-3601 NNP denotes ]
T3516 3601-3602 . denotes .
T3517 3603-3605 PRP denotes It
T3518 3606-3609 VBD denotes was
T3519 3610-3614 RB denotes also
T3520 3615-3623 VBN denotes reported
T3521 3624-3628 IN denotes that
T3522 3629-3639 JJ denotes endogenous
T3523 3640-3646 NN denotes IL-1Ra
T3524 3647-3656 NN denotes deficient
T3525 3657-3661 NNS denotes mice
T3526 3662-3671 VBD denotes developed
T3527 3672-3682 JJ denotes aggressive
T3528 3683-3689 NNS denotes tumors
T3529 3690-3699 VBG denotes following
T3530 3700-3708 NN denotes exposure
T3531 3709-3711 TO denotes to
T3532 3712-3723 NNS denotes carcinogens
T3533 3724-3725 NNP denotes [
T3534 3725-3727 CD denotes 17
T3535 3727-3728 NNP denotes ]
T3536 3728-3729 . denotes .
T3537 3730-3739 RB denotes Meanwhile
T3538 3739-3740 , denotes ,
T3539 3741-3754 NN denotes proliferation
T3540 3755-3757 IN denotes of
T3541 3758-3761 DT denotes the
T3542 3762-3770 NN denotes melanoma
T3543 3771-3776 NNS denotes cells
T3544 3777-3781 WDT denotes that
T3545 3782-3786 VBD denotes were
T3546 3787-3797 VBN denotes transduced
T3547 3798-3802 IN denotes with
T3548 3803-3809 JJ denotes IL-1Ra
T3549 3810-3814 NN denotes gene
T3550 3815-3818 VBD denotes was
T3551 3819-3826 VBN denotes reduced
T3552 3827-3830 CC denotes and
T3553 3831-3840 VBN denotes inhibited
T3554 3841-3849 NN denotes melanoma
T3555 3850-3861 NN denotes development
T3556 3862-3863 NNP denotes [
T3557 3863-3865 CD denotes 18
T3558 3865-3866 NNP denotes ]
T3559 3866-3867 . denotes .
T3560 3868-3873 NN denotes IL-1R
T3561 3874-3882 NN denotes blockade
T3562 3883-3887 RB denotes also
T3563 3888-3895 VBD denotes reduced
T3564 3896-3903 JJ denotes hepatic
T3565 3904-3909 NN denotes tumor
T3566 3910-3916 NN denotes growth
T3567 3917-3918 NNP denotes [
T3568 3918-3920 CD denotes 19
T3569 3920-3921 NNP denotes ]
T3570 3921-3922 . denotes .
T3571 3923-3931 RB denotes Moreover
T3572 3931-3932 , denotes ,
T3573 3933-3935 PRP denotes it
T3574 3936-3939 VBZ denotes has
T3575 3940-3944 RB denotes also
T3576 3945-3949 VBN denotes been
T3577 3950-3958 VBN denotes reported
T3578 3959-3963 IN denotes that
T3579 3964-3970 JJ denotes IL-1Ra
T3580 3971-3978 VBZ denotes reduces
T3581 3979-3991 NN denotes fibrosarcoma
T3582 3992-4003 NN denotes development
T3583 4004-4005 NNP denotes [
T3584 4005-4007 CD denotes 20
T3585 4007-4008 NNP denotes ]
T3586 4008-4009 , denotes ,
T3587 4010-4013 NNP denotes B16
T3588 4014-4022 NN denotes melanoma
T3589 4023-4029 NN denotes growth
T3590 4030-4033 CC denotes and
T3591 4034-4044 NN denotes metastasis
T3592 4045-4046 NNP denotes [
T3593 4046-4048 CD denotes 21
T3594 4048-4049 NNP denotes ]
T3595 4049-4050 , denotes ,
T3596 4051-4056 NN denotes colon
T3597 4057-4071 NN denotes adenocarcinoma
T3598 4072-4078 NN denotes growth
T3599 4079-4080 NNP denotes [
T3600 4080-4082 CD denotes 22
T3601 4082-4083 NNP denotes ]
T3602 4083-4084 , denotes ,
T3603 4085-4088 CC denotes and
T3604 4089-4093 NN denotes skin
T3605 4094-4100 NN denotes cancer
T3606 4101-4112 NN denotes development
T3607 4113-4114 NNP denotes [
T3608 4114-4116 CD denotes 23
T3609 4116-4117 NNP denotes ]
T3610 4117-4118 . denotes .
T3611 4119-4123 CD denotes IL-1
T3612 4124-4132 NN denotes knockout
T3613 4133-4137 NNS denotes mice
T3614 4138-4146 VBN denotes injected
T3615 4147-4151 IN denotes with
T3616 4152-4160 NN denotes melanoma
T3617 4161-4167 VBD denotes failed
T3618 4168-4170 TO denotes to
T3619 4171-4178 VB denotes develop
T3620 4179-4184 JJ denotes solid
T3621 4185-4191 NNS denotes tumors
T3622 4192-4193 NNP denotes [
T3623 4193-4195 CD denotes 24
T3624 4195-4196 NNP denotes ]
T3625 4196-4197 . denotes .
T3626 4198-4200 PRP denotes It
T3627 4201-4204 VBD denotes was
T3628 4205-4209 RB denotes also
T3629 4210-4215 VBN denotes found
T3630 4216-4220 IN denotes that
T3631 4221-4227 NN denotes IL-1Ra
T3632 4227-4228 , denotes ,
T3633 4229-4237 VBN denotes combined
T3634 4238-4242 IN denotes with
T3635 4243-4255 NN denotes temozolomide
T3636 4256-4259 CC denotes and
T3637 4260-4269 NN denotes docetaxel
T3638 4270-4282 NN denotes chemotherapy
T3639 4282-4283 , denotes ,
T3640 4284-4296 VBD denotes demonstrated
T3641 4297-4301 RBR denotes more
T3642 4302-4313 JJ denotes significant
T3643 4314-4323 NN denotes antitumor
T3644 4324-4332 NN denotes activity
T3645 4333-4340 IN denotes against
T3646 4341-4344 NNP denotes B16
T3647 4345-4353 NN denotes melanoma
T3648 4354-4359 NNS denotes cells
T3649 4360-4362 IN denotes in
T3650 4363-4367 NN denotes vivo
T3651 4368-4369 NNP denotes [
T3652 4369-4371 CD denotes 25
T3653 4371-4372 NNP denotes ]
T3654 4372-4373 . denotes .
T3655 4374-4379 DT denotes These
T3656 4380-4384 NNS denotes data
T3657 4385-4393 VBP denotes indicate
T3658 4394-4398 IN denotes that
T3659 4399-4405 NN denotes IL-1Ra
T3660 4406-4408 VBZ denotes is
T3661 4409-4418 JJ denotes important
T3662 4419-4421 IN denotes as
T3663 4422-4423 DT denotes a
T3664 4424-4429 NN denotes tumor
T3665 4430-4436 NN denotes growth
T3666 4437-4448 VBG denotes suppressing
T3667 4449-4457 NN denotes cytokine
T3668 4457-4458 . denotes .
T3669 4459-4464 JJ denotes NF-κB
T3670 4465-4470 NNS denotes plays
T3671 4471-4472 DT denotes a
T3672 4473-4480 JJ denotes crucial
T3673 4481-4485 NN denotes role
T3674 4486-4488 IN denotes in
T3675 4489-4492 DT denotes the
T3676 4493-4504 NN denotes suppression
T3677 4505-4507 IN denotes of
T3678 4508-4517 NN denotes apoptosis
T3679 4517-4518 , denotes ,
T3680 4519-4521 RB denotes as
T3681 4522-4526 RB denotes well
T3682 4527-4529 IN denotes as
T3683 4530-4533 DT denotes the
T3684 4534-4543 NN denotes induction
T3685 4544-4546 IN denotes of
T3686 4547-4551 NN denotes cell
T3687 4552-4565 NN denotes proliferation
T3688 4566-4569 CC denotes and
T3689 4570-4582 NN denotes inflammation
T3690 4582-4583 , denotes ,
T3691 4584-4587 CC denotes and
T3692 4588-4590 VBZ denotes is
T3693 4591-4598 RB denotes closely
T3694 4599-4609 VBN denotes associated
T3695 4610-4614 IN denotes with
T3696 4615-4621 NN denotes cancer
T3697 4622-4633 NN denotes development
T3698 4634-4635 NNP denotes [
T3699 4635-4637 CD denotes 26
T3700 4637-4638 NNP denotes ]
T3701 4638-4639 . denotes .
T3702 4640-4652 JJ denotes Constitutive
T3703 4653-4663 NN denotes activation
T3704 4664-4666 IN denotes of
T3705 4667-4672 NNP denotes NF-κB
T3706 4673-4676 VBZ denotes has
T3707 4677-4681 VBN denotes been
T3708 4682-4691 VBN denotes described
T3709 4692-4694 IN denotes in
T3710 4695-4696 DT denotes a
T3711 4697-4702 JJ denotes great
T3712 4703-4709 NN denotes number
T3713 4710-4712 IN denotes of
T3714 4713-4720 NNS denotes cancers
T3715 4721-4730 VBG denotes including
T3716 4731-4736 NN denotes colon
T3717 4737-4744 NNS denotes cancers
T3718 4744-4745 , denotes ,
T3719 4746-4754 NN denotes prostate
T3720 4755-4762 NNS denotes cancers
T3721 4763-4766 CC denotes and
T3722 4767-4775 NN denotes melanoma
T3723 4776-4777 NNP denotes [
T3724 4777-4779 CD denotes 27
T3725 4779-4780 NNP denotes ]
T3726 4780-4781 , denotes ,
T3727 4782-4785 CC denotes and
T3728 4786-4789 VBD denotes was
T3729 4790-4795 VBN denotes found
T3730 4796-4798 TO denotes to
T3731 4799-4810 VB denotes up-regulate
T3732 4811-4825 JJ denotes anti-apoptotic
T3733 4826-4831 NNS denotes genes
T3734 4832-4838 CC denotes and/or
T3735 4839-4843 RB denotes down
T3736 4844-4852 VB denotes regulate
T3737 4853-4862 JJ denotes apoptotic
T3738 4863-4867 NN denotes gene
T3739 4868-4878 NN denotes expression
T3740 4879-4880 NNP denotes [
T3741 4880-4882 CD denotes 28
T3742 4882-4883 NNP denotes ]
T3743 4883-4884 . denotes .
T3744 4885-4893 IN denotes Although
T3745 4894-4899 JJ denotes NF-κB
T3746 4900-4908 VBZ denotes promotes
T3747 4909-4914 NN denotes tumor
T3748 4915-4921 NN denotes growth
T3749 4921-4922 , denotes ,
T3750 4923-4925 PRP denotes it
T3751 4926-4928 VBZ denotes is
T3752 4929-4937 VBN denotes required
T3753 4938-4941 IN denotes for
T3754 4942-4945 DT denotes the
T3755 4946-4952 JJ denotes immune
T3756 4953-4959 NN denotes system
T3757 4960-4962 TO denotes to
T3758 4963-4971 VB denotes function
T3759 4972-4980 RB denotes normally
T3760 4981-4982 JJ denotes [
T3761 4982-4984 CD denotes 29
T3762 4984-4985 NN denotes ]
T3763 4985-4986 . denotes .
T3764 4987-4994 NNS denotes Studies
T3765 4995-4997 IN denotes on
T3766 4998-5013 JJ denotes c-Rel-deficient
T3767 5014-5018 NNS denotes mice
T3768 5019-5031 VBD denotes demonstrated
T3769 5032-5036 IN denotes that
T3770 5037-5042 NNP denotes c-Rel
T3771 5043-5045 VBZ denotes is
T3772 5046-5055 JJ denotes essential
T3773 5056-5059 IN denotes for
T3774 5060-5064 NNP denotes IL-2
T3775 5064-5065 , denotes ,
T3776 5066-5070 NNP denotes IL-3
T3777 5070-5071 , denotes ,
T3778 5072-5078 NNP denotes GM-CSF
T3779 5078-5079 , denotes ,
T3780 5080-5083 CC denotes and
T3781 5084-5088 NNP denotes IFNγ
T3782 5089-5099 NN denotes expression
T3783 5100-5102 IN denotes in
T3784 5103-5104 NNP denotes T
T3785 5105-5116 NNS denotes lymphocytes
T3786 5117-5118 NNP denotes [
T3787 5118-5120 CD denotes 30
T3788 5120-5121 NNP denotes ]
T3789 5121-5122 . denotes .
T3790 5123-5138 JJ denotes C-Rel-deficient
T3791 5139-5143 NNS denotes mice
T3792 5144-5148 RB denotes also
T3793 5149-5153 VBP denotes have
T3794 5154-5155 DT denotes a
T3795 5156-5171 JJ denotes tissue-specific
T3796 5172-5182 NN denotes deficiency
T3797 5183-5185 IN denotes of
T3798 5186-5193 JJ denotes various
T3799 5194-5203 NNS denotes cytokines
T3800 5204-5207 CC denotes and
T3801 5208-5214 NN denotes growth
T3802 5215-5222 NNS denotes factors
T3803 5223-5225 IN denotes in
T3804 5226-5227 NNP denotes T
T3805 5228-5233 NNS denotes cells
T3806 5234-5237 CC denotes and
T3807 5238-5249 NNS denotes macrophages
T3808 5250-5259 VBG denotes affecting
T3809 5260-5264 DT denotes both
T3810 5265-5271 NN denotes innate
T3811 5272-5275 CC denotes and
T3812 5276-5283 JJ denotes humoral
T3813 5284-5290 JJ denotes immune
T3814 5291-5300 NNS denotes responses
T3815 5301-5303 IN denotes in
T3816 5304-5307 DT denotes the
T3817 5308-5312 NN denotes host
T3818 5313-5314 NNP denotes [
T3819 5314-5316 CD denotes 31
T3820 5316-5317 NNP denotes ]
T3821 5317-5318 . denotes .
T3822 5319-5328 RB denotes Therefore
T3823 5328-5329 , denotes ,
T3824 5330-5335 NNP denotes NF-κB
T3825 5336-5339 MD denotes can
T3826 5340-5342 VB denotes be
T3827 5343-5352 RB denotes specially
T3828 5353-5361 VBN denotes targeted
T3829 5362-5364 TO denotes to
T3830 5365-5372 VB denotes prevent
T3831 5373-5379 NN denotes cancer
T3832 5380-5384 NN denotes cell
T3833 5385-5391 NN denotes growth
T3834 5392-5394 IN denotes by
T3835 5395-5396 -LRB- denotes (
T3836 5396-5397 CD denotes 1
T3837 5397-5398 -RRB- denotes )
T3838 5399-5407 RB denotes directly
T3839 5408-5417 VBG denotes affecting
T3840 5418-5427 JJ denotes apoptotic
T3841 5428-5434 NN denotes cancer
T3842 5435-5439 NN denotes cell
T3843 5440-5445 NN denotes death
T3844 5445-5446 , denotes ,
T3845 5447-5448 -LRB- denotes (
T3846 5448-5449 LS denotes 2
T3847 5449-5450 -RRB- denotes )
T3848 5451-5462 VBG denotes stimulating
T3849 5463-5468 NN denotes tumor
T3850 5469-5476 VBG denotes killing
T3851 5477-5488 NNS denotes lymphocytes
T3852 5489-5501 NN denotes infiltration
T3853 5502-5504 CC denotes or
T3854 5505-5506 -LRB- denotes (
T3855 5506-5507 LS denotes 3
T3856 5507-5508 -RRB- denotes )
T3857 5509-5519 VBG denotes increasing
T3858 5520-5523 DT denotes the
T3859 5524-5534 NN denotes production
T3860 5535-5537 IN denotes of
T3861 5538-5543 NN denotes tumor
T3862 5544-5551 VBG denotes killing
T3863 5552-5563 NNS denotes lymphokines
T3864 5563-5564 . denotes .
T3865 5565-5575 NNP denotes Activation
T3866 5576-5578 IN denotes of
T3867 5579-5584 NNP denotes NF-κB
T3868 5585-5587 VBZ denotes is
T3869 5588-5597 JJ denotes important
T3870 5598-5600 IN denotes in
T3871 5601-5604 DT denotes the
T3872 5605-5615 NN denotes regulation
T3873 5616-5618 IN denotes of
T3874 5619-5631 JJ denotes CCR-mediated
T3875 5632-5637 NN denotes tumor
T3876 5638-5644 NN denotes growth
T3877 5645-5648 CC denotes and
T3878 5649-5659 NN denotes metastasis
T3879 5659-5660 . denotes .
T3880 5661-5663 PRP denotes It
T3881 5664-5667 VBD denotes was
T3882 5668-5676 VBN denotes reported
T3883 5677-5681 IN denotes that
T3884 5682-5692 NN denotes inhibition
T3885 5693-5695 IN denotes of
T3886 5696-5701 NN denotes NF-κB
T3887 5702-5704 IN denotes by
T3888 5705-5736 NN denotes dehydroxymethyl-epoxyquinomicin
T3889 5737-5738 -LRB- denotes (
T3890 5738-5743 NNP denotes DHMEQ
T3891 5743-5744 -RRB- denotes )
T3892 5745-5752 VBZ denotes induces
T3893 5753-5757 NN denotes cell
T3894 5758-5763 NN denotes death
T3895 5764-5766 IN denotes of
T3896 5767-5774 JJ denotes primary
T3897 5775-5783 NN denotes effusion
T3898 5784-5792 NN denotes lymphoma
T3899 5793-5795 IN denotes by
T3900 5796-5806 NN denotes inhibition
T3901 5807-5809 IN denotes of
T3902 5810-5814 CD denotes CCR5
T3903 5815-5825 NN denotes expression
T3904 5826-5827 NNP denotes [
T3905 5827-5829 CD denotes 32
T3906 5829-5830 NNP denotes ]
T3907 5830-5831 . denotes .
T3908 5832-5842 NNP denotes Activation
T3909 5843-5845 IN denotes of
T3910 5846-5851 NNP denotes NF-κB
T3911 5852-5856 RB denotes also
T3912 5857-5866 VBZ denotes increases
T3913 5867-5880 JJ denotes CCL5-mediated
T3914 5881-5885 JJ denotes oral
T3915 5886-5892 NN denotes cancer
T3916 5893-5901 NN denotes motility
T3917 5902-5903 -LRB- denotes (
T3918 5903-5904 CD denotes 5
T3919 5904-5905 -RRB- denotes )
T3920 5906-5909 CC denotes and
T3921 5910-5914 NN denotes lung
T3922 5915-5925 NN denotes metastasis
T3923 5926-5927 NNP denotes [
T3924 5927-5929 CD denotes 33
T3925 5929-5930 NNP denotes ]
T3926 5930-5931 . denotes .
T3927 5932-5936 RB denotes Thus
T3928 5936-5937 , denotes ,
T3929 5938-5940 PRP denotes it
T3930 5941-5943 VBZ denotes is
T3931 5944-5952 JJ denotes possible
T3932 5953-5957 IN denotes that
T3933 5958-5968 NN denotes inhibition
T3934 5969-5971 IN denotes of
T3935 5972-5977 NN denotes NF-κB
T3936 5978-5983 MD denotes could
T3937 5984-5986 VB denotes be
T3938 5987-5995 VBN denotes involved
T3939 5996-5998 IN denotes in
T3940 5999-6003 NNP denotes CCR5
T3941 6004-6012 VBD denotes mediated
T3942 6013-6018 NN denotes tumor
T3943 6019-6030 NN denotes development
T3944 6030-6031 . denotes .
T3945 6032-6037 JJ denotes NF-κB
T3946 6038-6051 NN denotes transcription
T3947 6052-6058 NN denotes factor
T3948 6059-6066 JJ denotes binding
T3949 6067-6072 NNS denotes sites
T3950 6073-6076 VBP denotes are
T3951 6077-6084 JJ denotes present
T3952 6085-6087 IN denotes in
T3953 6088-6091 DT denotes the
T3954 6092-6100 NN denotes promoter
T3955 6101-6107 NN denotes region
T3956 6108-6110 IN denotes of
T3957 6111-6126 JJ denotes proinflammatory
T3958 6127-6135 NN denotes cytokine
T3959 6136-6141 NNS denotes genes
T3960 6141-6142 , denotes ,
T3961 6143-6147 JJ denotes such
T3962 6148-6150 IN denotes as
T3963 6151-6160 NN denotes IL-1alpha
T3964 6160-6161 , denotes ,
T3965 6162-6166 NNP denotes IL-6
T3966 6166-6167 , denotes ,
T3967 6168-6174 NNP denotes GM-CSF
T3968 6174-6175 , denotes ,
T3969 6176-6179 CC denotes and
T3970 6180-6182 NNP denotes KC
T3971 6183-6184 NNP denotes [
T3972 6184-6186 CD denotes 34
T3973 6186-6187 NNP denotes ]
T3974 6187-6188 . denotes .
T3975 6189-6191 IN denotes On
T3976 6192-6195 DT denotes the
T3977 6196-6201 JJ denotes other
T3978 6202-6206 NN denotes hand
T3979 6206-6207 , denotes ,
T3980 6208-6211 DT denotes the
T3981 6212-6218 NN denotes IL-1Ra
T3982 6219-6221 VBZ denotes is
T3983 6222-6223 DT denotes a
T3984 6224-6232 JJ denotes negative
T3985 6233-6242 NN denotes regulator
T3986 6243-6245 IN denotes of
T3987 6246-6249 DT denotes the
T3988 6250-6262 JJ denotes inflammatory
T3989 6263-6271 NN denotes response
T3990 6271-6272 . denotes .
T3991 6273-6280 JJ denotes Several
T3992 6281-6288 NNS denotes studies
T3993 6289-6293 VBP denotes have
T3994 6294-6306 VBN denotes demonstrated
T3995 6307-6310 DT denotes the
T3996 6311-6318 NN denotes ability
T3997 6319-6321 IN denotes of
T3998 6322-6328 NN denotes IL-1Ra
T3999 6329-6331 TO denotes to
T4000 6332-6340 VB denotes abrogate
T4001 6341-6344 DT denotes the
T4002 6345-6360 JJ denotes proinflammatory
T4003 6361-6368 NNS denotes effects
T4004 6369-6371 IN denotes of
T4005 6372-6376 NN denotes IL-1
T4006 6376-6377 . denotes .
T4007 6378-6383 NNP denotes Smith
T4008 6384-6386 FW denotes et
T4009 6387-6390 FW denotes al.
T4010 6391-6400 VBD denotes suggested
T4011 6401-6405 IN denotes that
T4012 6406-6409 DT denotes the
T4013 6410-6420 NN denotes regulation
T4014 6421-6423 IN denotes of
T4015 6424-6430 NN denotes IL-1Ra
T4016 6431-6435 NN denotes gene
T4017 6436-6446 NN denotes expression
T4018 6447-6449 VBZ denotes is
T4019 6450-6451 DT denotes a
T4020 6452-6459 JJ denotes complex
T4021 6460-6465 NN denotes event
T4022 6466-6475 VBG denotes involving
T4023 6476-6479 DT denotes the
T4024 6480-6492 NNS denotes interactions
T4025 6493-6495 IN denotes of
T4026 6496-6501 CD denotes three
T4027 6502-6511 JJ denotes different
T4028 6512-6525 NN denotes transcription
T4029 6526-6533 NNS denotes factors
T4030 6533-6534 : denotes ;
T4031 6535-6540 NNP denotes NF-κB
T4032 6540-6541 NNP denotes /
T4033 6541-6543 NNP denotes PU
T4034 6543-6545 CD denotes .1
T4035 6545-6546 CD denotes /
T4036 6546-6556 JJ denotes GA-binding
T4037 6557-6564 NN denotes protein
T4038 6565-6572 JJ denotes binding
T4039 6573-6577 NN denotes site
T4040 6578-6579 NNP denotes [
T4041 6579-6581 CD denotes 35
T4042 6581-6582 NNP denotes ]
T4043 6582-6583 . denotes .
T4044 6584-6591 NNP denotes Nuclear
T4045 6592-6605 NN denotes translocation
T4046 6606-6608 IN denotes of
T4047 6609-6614 NNP denotes NF-κB
T4048 6615-6616 -LRB- denotes (
T4049 6616-6619 NNS denotes p65
T4050 6619-6620 -RRB- denotes )
T4051 6621-6624 VBD denotes was
T4052 6625-6638 RB denotes significantly
T4053 6639-6647 VBN denotes enhanced
T4054 6648-6651 CC denotes and
T4055 6652-6661 VBN denotes prolonged
T4056 6662-6664 IN denotes in
T4057 6665-6681 JJ denotes IL-1Ra-deficient
T4058 6682-6686 NNS denotes mice
T4059 6686-6687 , denotes ,
T4060 6688-6696 VBN denotes compared
T4061 6697-6699 TO denotes to
T4062 6700-6704 DT denotes that
T4063 6705-6707 IN denotes in
T4064 6708-6712 JJ denotes wild
T4065 6713-6717 NN denotes type
T4066 6718-6722 NNS denotes mice
T4067 6723-6724 NNP denotes [
T4068 6724-6726 CD denotes 36
T4069 6726-6727 NNP denotes ]
T4070 6727-6728 . denotes .
T4071 6729-6742 JJ denotes Intracellular
T4072 6743-6749 NN denotes IL-1Ra
T4073 6750-6751 -LRB- denotes (
T4074 6751-6759 NN denotes icIL-1Ra
T4075 6759-6760 -RRB- denotes )
T4076 6761-6764 VBD denotes was
T4077 6765-6770 VBN denotes found
T4078 6771-6773 TO denotes to
T4079 6774-6781 VB denotes inhibit
T4080 6782-6786 NN denotes IL-1
T4081 6787-6789 IN denotes by
T4082 6790-6798 VBG denotes blocking
T4083 6799-6804 JJ denotes NF-κB
T4084 6805-6811 NN denotes signal
T4085 6812-6824 NN denotes transduction
T4086 6825-6833 NNS denotes pathways
T4087 6834-6836 IN denotes in
T4088 6837-6849 JJ denotes inflammatory
T4089 6850-6859 NNS denotes responses
T4090 6860-6861 NNP denotes [
T4091 6861-6863 CD denotes 37
T4092 6863-6864 NNP denotes ]
T4093 6864-6865 . denotes .
T4094 6866-6873 IN denotes Because
T4095 6874-6878 NN denotes IL-1
T4096 6879-6882 VBZ denotes has
T4097 6883-6887 VBN denotes been
T4098 6888-6893 VBN denotes shown
T4099 6894-6896 TO denotes to
T4100 6897-6899 VB denotes be
T4101 6900-6902 DT denotes an
T4102 6903-6910 NN denotes inducer
T4103 6911-6913 IN denotes of
T4104 6914-6919 JJ denotes NF-κB
T4105 6920-6930 NN denotes activation
T4106 6931-6932 NNP denotes [
T4107 6932-6934 CD denotes 38
T4108 6934-6935 NNP denotes ]
T4109 6935-6936 , denotes ,
T4110 6937-6939 PRP denotes we
T4111 6940-6952 VBD denotes hypothesized
T4112 6953-6957 IN denotes that
T4113 6958-6961 DT denotes the
T4114 6962-6972 NN denotes expression
T4115 6973-6975 IN denotes of
T4116 6976-6982 NN denotes IL-1Ra
T4117 6983-6988 MD denotes could
T4118 6989-6993 VB denotes play
T4119 6994-6996 DT denotes an
T4120 6997-7006 JJ denotes important
T4121 7007-7011 NN denotes role
T4122 7012-7014 IN denotes in
T4123 7015-7018 DT denotes the
T4124 7019-7028 NN denotes autocrine
T4125 7029-7039 NN denotes activation
T4126 7040-7042 IN denotes of
T4127 7043-7056 NN denotes transcription
T4128 7057-7064 NNS denotes factors
T4129 7065-7070 VBP denotes NF-κB
T4130 7071-7073 CC denotes or
T4131 7074-7078 NN denotes vice
T4132 7079-7084 RB denotes versa
T4133 7084-7085 . denotes .
T4134 7086-7090 RB denotes Thus
T4135 7090-7091 , denotes ,
T4136 7092-7095 DT denotes the
T4137 7096-7099 NN denotes aim
T4138 7100-7102 IN denotes of
T4139 7103-7107 DT denotes this
T4140 7108-7113 NN denotes study
T4141 7114-7117 VBD denotes was
T4142 7118-7120 TO denotes to
T4143 7121-7129 VB denotes evaluate
T4144 7130-7133 DT denotes the
T4145 7134-7139 NNS denotes roles
T4146 7140-7142 IN denotes of
T4147 7143-7148 NN denotes NF-κB
T4148 7149-7152 CC denotes and
T4149 7153-7159 NN denotes IL-1Ra
T4150 7160-7162 IN denotes in
T4151 7163-7166 DT denotes the
T4152 7167-7176 NN denotes chemokine
T4153 7177-7185 NN denotes receptor
T4154 7186-7199 JJ denotes CCR5-mediated
T4155 7200-7211 NN denotes suppression
T4156 7212-7214 IN denotes of
T4157 7215-7220 NN denotes tumor
T4158 7221-7232 NN denotes development
T4159 7232-7233 . denotes .
T5228 7244-7254 NNP denotes Inhibition
T5229 7255-7257 IN denotes of
T5230 7258-7263 NNP denotes Tumor
T5231 7264-7275 NNP denotes Development
T5232 7276-7278 IN denotes in
T5233 7279-7283 NNP denotes CCR5
T5234 7283-7284 NNP denotes −
T5235 7284-7285 VBD denotes /
T5236 7285-7286 CD denotes −
T5237 7287-7291 NNP denotes Mice
T5238 7292-7295 DT denotes The
T5239 7296-7302 NN denotes effect
T5240 7303-7305 IN denotes of
T5241 7306-7310 CD denotes CCR5
T5242 7311-7313 IN denotes in
T5243 7314-7319 NN denotes tumor
T5244 7320-7331 NN denotes development
T5245 7332-7335 VBD denotes was
T5246 7336-7348 VBN denotes investigated
T5247 7349-7354 VBG denotes using
T5248 7355-7359 NNP denotes CCR5
T5249 7359-7360 NNP denotes +
T5250 7360-7361 VBD denotes /
T5251 7361-7362 CD denotes +
T5252 7363-7366 CC denotes and
T5253 7367-7371 CD denotes CCR5
T5254 7371-7372 CD denotes −
T5255 7372-7373 NN denotes /
T5256 7373-7374 NN denotes −
T5257 7375-7379 NNS denotes mice
T5258 7379-7380 . denotes .
T5259 7381-7387 CD denotes B16-F0
T5260 7388-7396 NN denotes melanoma
T5261 7397-7402 NNS denotes cells
T5262 7403-7407 VBD denotes were
T5263 7408-7418 VBN denotes inoculated
T5264 7419-7433 RB denotes subcutaneously
T5265 7434-7438 IN denotes into
T5266 7439-7443 CD denotes CCR5
T5267 7443-7444 CD denotes +
T5268 7444-7445 NN denotes /
T5269 7445-7446 NN denotes +
T5270 7447-7450 CC denotes and
T5271 7451-7455 CD denotes CCR5
T5272 7455-7456 CD denotes −
T5273 7456-7457 NN denotes /
T5274 7457-7458 NN denotes −
T5275 7459-7463 NNS denotes mice
T5276 7464-7465 -LRB- denotes (
T5277 7465-7466 FW denotes n
T5278 7467-7468 SYM denotes =
T5279 7469-7471 CD denotes 20
T5280 7471-7472 -RRB- denotes )
T5281 7472-7473 . denotes .
T5282 7474-7479 NN denotes Tumor
T5283 7480-7486 NN denotes growth
T5284 7487-7490 VBD denotes was
T5285 7491-7500 VBN denotes monitored
T5286 7501-7504 IN denotes for
T5287 7505-7507 CD denotes 31
T5288 7508-7512 NNS denotes days
T5289 7512-7513 . denotes .
T5290 7514-7519 NN denotes Tumor
T5291 7520-7526 NN denotes growth
T5292 7527-7529 IN denotes in
T5293 7530-7533 DT denotes the
T5294 7534-7538 NNP denotes CCR5
T5295 7538-7539 NNP denotes −
T5296 7539-7540 VBD denotes /
T5297 7540-7541 CD denotes −
T5298 7542-7546 NNS denotes mice
T5299 7547-7550 VBD denotes was
T5300 7551-7564 RB denotes significantly
T5301 7565-7570 JJR denotes lower
T5302 7571-7575 IN denotes than
T5303 7576-7580 DT denotes that
T5304 7581-7583 IN denotes in
T5305 7584-7587 DT denotes the
T5306 7588-7592 NNP denotes CCR5
T5307 7592-7593 NNP denotes +
T5308 7593-7594 VBD denotes /
T5309 7594-7595 CD denotes +
T5310 7596-7600 NNS denotes mice
T5311 7600-7601 . denotes .
T5312 7602-7605 DT denotes The
T5313 7606-7611 NN denotes tumor
T5314 7612-7618 NN denotes growth
T5315 7619-7621 IN denotes in
T5316 7622-7625 DT denotes the
T5317 7626-7630 NNP denotes CCR5
T5318 7630-7631 NNP denotes −
T5319 7631-7632 VBD denotes /
T5320 7632-7633 CD denotes −
T5321 7634-7638 NNS denotes mice
T5322 7639-7642 VBD denotes was
T5351 7643-7650 VBN denotes reduced
T5352 7651-7653 TO denotes to
T4871 7654-7658 CD denotes 19.1
T4872 7658-7659 NN denotes %
T4873 7659-7660 , denotes ,
T4874 7661-7668 IN denotes whereas
T4875 7669-7672 DT denotes the
T4876 7673-7678 NN denotes tumor
T4877 7679-7685 NN denotes growth
T4878 7686-7688 IN denotes in
T4879 7689-7692 DT denotes the
T4880 7693-7697 NNP denotes CCR5
T4881 7697-7698 NNP denotes +
T4882 7698-7699 VBD denotes /
T4883 7699-7700 CD denotes +
T4884 7701-7705 NNS denotes mice
T4885 7706-7709 VBD denotes was
T4886 7710-7714 RB denotes only
T4887 7715-7722 VBN denotes reduced
T4888 7723-7725 TO denotes to
T4889 7726-7730 CD denotes 24.3
T4890 7730-7731 NN denotes %
T4891 7731-7732 , denotes ,
T4892 7733-7735 IN denotes in
T4893 7736-7740 DT denotes both
T4894 7741-7746 NN denotes tumor
T4895 7747-7753 NN denotes weight
T4896 7754-7755 -LRB- denotes (
T4897 7755-7761 NN denotes Figure
T4898 7762-7764 CD denotes 1A
T4899 7765-7768 CC denotes and
T4900 7769-7771 CD denotes 1B
T4901 7771-7772 -RRB- denotes )
T4902 7773-7776 CC denotes and
T4903 7777-7782 NN denotes tumor
T4904 7783-7789 NN denotes volume
T4905 7789-7790 , denotes ,
T4906 7791-7803 RB denotes respectively
T4907 7804-7805 -LRB- denotes (
T4908 7805-7811 NN denotes Figure
T4909 7812-7814 CD denotes 1A
T4910 7815-7818 CC denotes and
T4911 7819-7821 CD denotes 1C
T4912 7821-7822 -RRB- denotes )
T4913 7822-7823 . denotes .
T4914 7824-7829 DT denotes These
T4915 7830-7837 NNS denotes results
T4916 7838-7848 VBN denotes correlated
T4917 7849-7853 IN denotes with
T4918 7854-7858 NNS denotes mice
T4919 7859-7867 NN denotes survival
T4920 7868-7873 NNS denotes rates
T4921 7873-7874 . denotes .
T4922 7875-7880 EX denotes There
T4923 7881-7884 VBD denotes was
T4924 7885-7886 DT denotes a
T4925 7887-7898 JJ denotes significant
T4926 7899-7909 NN denotes difference
T4927 7910-7912 IN denotes in
T4928 7913-7921 NN denotes survival
T4929 7922-7927 NNS denotes rates
T4930 7928-7935 IN denotes between
T4931 7936-7940 CD denotes CCR5
T4932 7940-7941 CD denotes −
T4933 7941-7942 NN denotes /
T4934 7942-7943 NN denotes −
T4935 7944-7948 NNS denotes mice
T4936 7949-7950 -LRB- denotes (
T4937 7950-7952 CD denotes 75
T4938 7952-7953 NN denotes %
T4939 7954-7956 IN denotes of
T4940 7957-7965 VBG denotes starting
T4941 7966-7970 NN denotes time
T4942 7970-7971 -RRB- denotes )
T4943 7972-7975 CC denotes and
T4944 7976-7980 CD denotes CCR5
T4945 7980-7981 CD denotes +
T4946 7981-7982 NN denotes /
T4947 7982-7983 NN denotes +
T4948 7984-7988 NNS denotes mice
T4949 7989-7990 -LRB- denotes (
T4950 7990-7992 CD denotes 15
T4951 7992-7993 NN denotes %
T4952 7993-7994 -RRB- denotes )
T4953 7995-7997 IN denotes at
T4954 7998-8001 DT denotes the
T4955 8002-8005 NN denotes end
T4956 8006-8008 IN denotes of
T4957 8009-8012 DT denotes the
T4958 8013-8023 NN denotes experiment
T4959 8024-8025 -LRB- denotes (
T4960 8025-8031 NN denotes Figure
T4961 8032-8034 CD denotes 1D
T4962 8034-8035 -RRB- denotes )
T4963 8035-8036 . denotes .
T4964 8037-8042 EX denotes There
T4965 8043-8046 VBD denotes was
T4966 8047-8048 DT denotes a
T4967 8049-8060 JJ denotes significant
T4968 8061-8071 NN denotes difference
T4969 8072-8074 IN denotes in
T4970 8075-8083 NN denotes survival
T4971 8084-8089 NNS denotes rates
T4972 8090-8097 IN denotes between
T4973 8098-8102 CD denotes CCR5
T4974 8102-8103 CD denotes −
T4975 8103-8104 NN denotes /
T4976 8104-8105 NN denotes −
T4977 8106-8110 NNS denotes mice
T4978 8111-8114 CC denotes and
T4979 8115-8119 NNS denotes CCR5
T4980 8119-8120 VBP denotes +
T4981 8120-8121 CD denotes /
T4982 8121-8122 CD denotes +
T4983 8123-8127 NNS denotes mice
T4984 8127-8128 . denotes .
T4985 8129-8131 IN denotes At
T4986 8132-8135 DT denotes the
T4987 8136-8139 NN denotes end
T4988 8140-8142 IN denotes of
T4989 8143-8146 DT denotes the
T4990 8147-8157 NN denotes experiment
T4991 8157-8158 , denotes ,
T4992 8159-8161 CD denotes 75
T4993 8161-8162 NN denotes %
T4994 8163-8165 IN denotes of
T4995 8166-8169 DT denotes the
T4996 8170-8174 NNP denotes CCR5
T4997 8174-8175 NNP denotes −
T4998 8175-8176 VBD denotes /
T4999 8176-8177 CD denotes −
T5000 8178-8182 NNS denotes mice
T5001 8183-8191 VBD denotes survived
T5002 8192-8197 IN denotes while
T5003 8198-8202 RB denotes only
T5004 8203-8205 CD denotes 15
T5005 8205-8206 NN denotes %
T5006 8207-8209 IN denotes of
T5007 8210-8213 DT denotes the
T5008 8214-8218 NNP denotes CCR5
T5009 8218-8219 NNP denotes +
T5010 8219-8220 VBD denotes /
T5011 8220-8221 CD denotes +
T5012 8222-8226 NNS denotes mice
T5013 8227-8235 VBD denotes survived
T5014 8235-8236 . denotes .
T5015 8237-8249 JJ denotes Subcutaneous
T5016 8250-8256 NNS denotes tumors
T5017 8257-8261 VBD denotes were
T5018 8262-8271 VBN denotes harvested
T5019 8272-8276 IN denotes from
T5020 8277-8280 DT denotes the
T5021 8281-8291 JJ denotes sacrificed
T5022 8292-8296 NNS denotes mice
T5023 8297-8299 CD denotes 31
T5024 8300-8304 NNS denotes days
T5025 8305-8310 IN denotes after
T5026 8311-8322 NN denotes inoculation
T5027 8322-8323 . denotes .
T5028 8324-8327 DT denotes The
T5029 8328-8347 JJ denotes immunohistochemical
T5030 8348-8356 NN denotes analysis
T5031 8357-8359 IN denotes of
T5032 8360-8365 NN denotes tumor
T5033 8366-8374 NNS denotes sections
T5034 8374-8375 , denotes ,
T5035 8376-8383 VBN denotes stained
T5036 8384-8388 IN denotes with
T5037 8389-8392 NNP denotes H&E
T5038 8393-8396 CC denotes and
T5039 8397-8400 IN denotes for
T5040 8401-8414 NN denotes proliferation
T5041 8415-8422 NN denotes antigen
T5042 8423-8427 NNP denotes PCNA
T5043 8427-8428 , denotes ,
T5044 8429-8437 VBD denotes revealed
T5045 8438-8445 JJR denotes greater
T5046 8446-8456 NN denotes inhibition
T5047 8457-8459 IN denotes of
T5048 8460-8465 NN denotes tumor
T5049 8466-8470 NN denotes cell
T5050 8471-8477 NN denotes growth
T5051 8478-8480 IN denotes in
T5052 8481-8485 CD denotes CCR5
T5053 8485-8486 CD denotes −
T5054 8486-8487 NN denotes /
T5055 8487-8488 NN denotes −
T5056 8489-8493 NNS denotes mice
T5057 8493-8494 . denotes .
T5058 8495-8498 DT denotes The
T5059 8499-8509 JJ denotes histologic
T5060 8510-8518 NNS denotes findings
T5061 8519-8524 IN denotes after
T5062 8525-8528 NNP denotes H&E
T5063 8529-8537 VBG denotes staining
T5064 8538-8547 VBD denotes indicated
T5065 8548-8552 IN denotes that
T5066 8553-8556 DT denotes the
T5067 8557-8562 NN denotes tumor
T5068 8563-8570 NNS denotes tissues
T5069 8571-8573 IN denotes of
T5070 8574-8577 DT denotes the
T5071 8578-8582 NNP denotes CCR5
T5072 8582-8583 NNP denotes −
T5073 8583-8584 VBD denotes /
T5074 8584-8585 CD denotes −
T5075 8586-8590 NNS denotes mice
T5076 8590-8591 , denotes ,
T5077 8592-8595 CC denotes but
T5078 8596-8599 RB denotes not
T5079 8600-8605 DT denotes those
T5080 8606-8608 IN denotes of
T5081 8609-8612 DT denotes the
T5082 8613-8617 NNP denotes CCR5
T5083 8617-8618 NNP denotes +
T5084 8618-8619 VBD denotes /
T5085 8619-8620 CD denotes +
T5086 8621-8625 NNS denotes mice
T5087 8625-8626 , denotes ,
T5088 8627-8636 VBD denotes contained
T5089 8637-8642 JJ denotes large
T5090 8643-8648 NNS denotes areas
T5091 8649-8651 IN denotes of
T5092 8652-8660 NN denotes necrosis
T5093 8660-8661 . denotes .
T5094 8662-8666 NNP denotes PCNA
T5095 8667-8675 JJ denotes reactive
T5096 8676-8681 NNS denotes cells
T5097 8682-8686 VBD denotes were
T5098 8687-8700 RB denotes significantly
T5099 8701-8708 VBN denotes reduced
T5100 8709-8711 IN denotes in
T5101 8712-8715 DT denotes the
T5102 8716-8720 NNP denotes CCR5
T5103 8720-8721 NNP denotes −
T5104 8721-8722 VBD denotes /
T5105 8722-8723 CD denotes −
T5106 8724-8728 NNS denotes mice
T5107 8729-8730 -LRB- denotes (
T5108 8730-8736 NN denotes Figure
T5109 8737-8739 CD denotes 1E
T5110 8739-8740 -RRB- denotes )
T5111 8740-8741 . denotes .
T17423 8786-8796 NNP denotes Inhibition
T17424 8797-8799 IN denotes of
T17425 8800-8805 NN denotes tumor
T17426 8806-8817 NN denotes development
T17427 8818-8820 IN denotes in
T17428 8821-8825 CD denotes CCR5
T17429 8825-8826 CD denotes −
T17430 8826-8827 NN denotes /
T17431 8827-8828 NN denotes −
T17432 8829-8833 NNS denotes mice
T17433 8833-8834 . denotes .
T17434 8835-8836 DT denotes A
T17435 8837-8838 NNP denotes C
T17436 8838-8839 , denotes ,
T17437 8840-8845 NNP denotes Tumor
T17438 8846-8852 NNS denotes images
T17439 8852-8853 , denotes ,
T17440 8854-8861 NNS denotes volumes
T17441 8861-8862 , denotes ,
T17442 8863-8866 CC denotes and
T17443 8867-8874 NNS denotes weights
T17444 8874-8875 . denotes .
T17445 8876-8879 CD denotes B16
T17446 8880-8888 NN denotes melanoma
T17447 8889-8894 NNS denotes cells
T17448 8895-8896 -LRB- denotes (
T17449 8896-8897 CD denotes 5
T17450 8897-8898 CD denotes ×
T17451 8898-8901 CD denotes 105
T17452 8902-8913 NN denotes cells/mouse
T17453 8913-8914 -RRB- denotes )
T17454 8915-8919 VBD denotes were
T17455 8920-8930 VBN denotes inoculated
T17456 8931-8935 RB denotes s.c.
T17457 8936-8940 IN denotes into
T17458 8941-8945 CD denotes CCR5
T17459 8945-8946 CD denotes +
T17460 8946-8947 NN denotes /
T17461 8947-8948 NN denotes +
T17462 8949-8953 NNS denotes mice
T17463 8954-8957 CC denotes and
T17464 8958-8962 NNS denotes CCR5
T17465 8962-8963 VBP denotes −
T17466 8963-8964 CD denotes /
T17467 8964-8965 CD denotes −
T17468 8966-8970 NNS denotes mice
T17469 8971-8972 -LRB- denotes (
T17470 8972-8973 FW denotes n
T17471 8974-8975 SYM denotes =
T17472 8976-8978 CD denotes 20
T17473 8978-8979 -RRB- denotes )
T17474 8979-8980 . denotes .
T17475 8981-8986 NN denotes Tumor
T17476 8987-8994 NNS denotes volumes
T17477 8995-8999 VBD denotes were
T17478 9000-9008 VBN denotes measured
T17479 9009-9014 DT denotes every
T17480 9015-9018 NN denotes day
T17481 9019-9022 CC denotes and
T17482 9023-9028 NN denotes tumor
T17483 9029-9036 NNS denotes weights
T17484 9037-9041 VBD denotes were
T17485 9042-9050 VBN denotes measured
T17486 9051-9053 IN denotes at
T17487 9054-9059 NN denotes study
T17488 9060-9071 NN denotes termination
T17489 9072-9073 -LRB- denotes (
T17490 9073-9076 NNP denotes Day
T17491 9077-9079 CD denotes 31
T17492 9079-9080 -RRB- denotes )
T17493 9080-9081 . denotes .
T17494 9082-9085 DT denotes The
T17495 9086-9090 NNP denotes CCR5
T17496 9090-9091 NNP denotes −
T17497 9091-9092 VBD denotes /
T17498 9092-9093 CD denotes −
T17499 9094-9098 NNS denotes mice
T17500 9099-9102 VBD denotes had
T17501 9103-9104 DT denotes a
T17502 9105-9116 JJ denotes significant
T17503 9117-9126 NN denotes reduction
T17504 9127-9129 IN denotes in
T17505 9130-9135 NN denotes tumor
T17506 9136-9142 NN denotes growth
T17507 9143-9146 CC denotes and
T17508 9147-9153 NN denotes volume
T17509 9154-9156 IN denotes as
T17510 9157-9165 VBN denotes compared
T17511 9166-9168 TO denotes to
T17512 9169-9173 CD denotes CCR5
T17513 9173-9174 CD denotes +
T17514 9174-9175 NN denotes /
T17515 9175-9176 NN denotes +
T17516 9177-9181 NNS denotes mice
T17526 9181-9182 . denotes .
T17527 9183-9186 DT denotes The
T17528 9187-9194 NNS denotes results
T17529 9195-9198 VBP denotes are
T17530 9199-9208 VBN denotes expressed
T17531 9209-9211 IN denotes as
T17532 9212-9216 JJ denotes mean
T17533 9217-9218 NN denotes ±
T17534 9219-9221 NNP denotes SD
T17535 9221-9222 . denotes .
T17536 9223-9224 SYM denotes *
T17537 9225-9234 VBZ denotes indicates
T17538 9235-9246 JJ denotes significant
T17539 9247-9257 NN denotes difference
T17540 9258-9262 IN denotes from
T17541 9263-9267 CD denotes CCR5
T17542 9267-9268 CD denotes +
T17543 9268-9269 NN denotes /
T17544 9269-9270 NN denotes +
T17545 9271-9275 NNS denotes mice
T17546 9276-9277 -LRB- denotes (
T17547 9277-9278 NNP denotes P
T17548 9278-9279 CD denotes <
T17549 9279-9283 CD denotes 0.05
T17550 9283-9284 -RRB- denotes )
T17551 9284-9285 . denotes .
T17552 9286-9287 NNP denotes D
T17553 9287-9288 , denotes ,
T17554 9289-9292 DT denotes The
T17555 9293-9297 NNP denotes CCR5
T17556 9297-9298 NNP denotes −
T17557 9298-9299 VBD denotes /
T17558 9299-9300 CD denotes −
T17559 9301-9305 NNS denotes mice
T17560 9306-9318 VBD denotes demonstrated
T17561 9319-9332 RB denotes significantly
T17562 9333-9339 JJR denotes higher
T17563 9340-9348 NN denotes survival
T17564 9349-9354 NNS denotes rates
T17565 9355-9363 VBN denotes compared
T17566 9364-9366 TO denotes to
T17567 9367-9371 CD denotes CCR5
T17568 9371-9372 CD denotes +
T17569 9372-9373 NN denotes /
T17570 9373-9374 NN denotes +
T17571 9375-9379 NNS denotes mice
T17572 9380-9381 -LRB- denotes (
T17573 9381-9383 IN denotes by
T17574 9384-9392 JJ denotes Log-rank
T17575 9393-9397 NN denotes Test
T17576 9397-9398 -RRB- denotes )
T17577 9398-9399 . denotes .
T17578 9400-9402 NNP denotes E.
T17579 9403-9408 NNP denotes Tumor
T17580 9409-9417 NNS denotes sections
T17581 9418-9422 VBD denotes were
T17582 9423-9431 VBN denotes analyzed
T17583 9432-9434 IN denotes by
T17584 9435-9438 NNP denotes H&E
T17585 9439-9444 VB denotes stain
T17586 9445-9448 CC denotes and
T17587 9449-9459 NN denotes expression
T17588 9460-9462 IN denotes of
T17589 9463-9476 VBG denotes proliferating
T17590 9477-9481 NN denotes cell
T17591 9482-9489 JJ denotes nuclear
T17592 9490-9497 NN denotes antigen
T17593 9498-9499 -LRB- denotes (
T17594 9499-9503 NNP denotes PCNA
T17595 9503-9504 -RRB- denotes )
T17596 9505-9507 IN denotes by
T17597 9508-9528 NN denotes immunohistochemistry
T17598 9528-9529 . denotes .
T17599 9530-9534 NNS denotes Data
T17600 9535-9538 VBP denotes are
T17601 9539-9544 VBZ denotes means
T17602 9545-9546 NNP denotes ±
T17603 9547-9551 NNP denotes S.D.
T17604 9552-9554 IN denotes of
T17605 9555-9559 CD denotes four
T17640 9560-9572 JJ denotes experimental
T17641 9573-9580 NNS denotes animals
T17642 9580-9581 . denotes .
T17643 9582-9583 SYM denotes *
T17644 9584-9593 VBZ denotes indicates
T17645 9594-9605 JJ denotes significant
T17646 9606-9616 NN denotes difference
T17647 9617-9621 IN denotes from
T17648 9622-9626 CD denotes CCR5
T17649 9626-9627 CD denotes +
T17650 9627-9628 NN denotes /
T17651 9628-9629 NN denotes +
T17652 9630-9634 NNS denotes mice
T17653 9635-9636 -LRB- denotes (
T17654 9636-9637 NNP denotes P
T17655 9637-9638 CD denotes <
T17656 9638-9642 CD denotes 0.05
T17657 9642-9643 -RRB- denotes )
T17658 9643-9644 . denotes .
T17659 9645-9650 NNP denotes Scale
T17660 9651-9654 NN denotes bar
T17661 9655-9664 VBZ denotes indicates
T17662 9665-9667 CD denotes 50
T17663 9668-9670 NN denotes m.
T17906 9672-9680 NN denotes Decrease
T5636 9672-9680 NN denotes Decrease
T17907 9681-9683 IN denotes of
T5637 9681-9683 IN denotes of
T17908 9684-9689 JJ denotes NF-κB
T5638 9684-9689 NNP denotes NF-κB
T17909 9690-9698 NN denotes Activity
T5639 9690-9698 NNP denotes Activity
T17910 9699-9701 IN denotes in
T5640 9699-9701 IN denotes in
T17911 9702-9707 NN denotes Tumor
T5641 9702-9707 NNP denotes Tumor
T17912 9708-9714 NN denotes Tissue
T5642 9708-9714 NNP denotes Tissue
T17913 9715-9717 IN denotes of
T5643 9715-9717 IN denotes of
T17914 9718-9722 CD denotes CCR5
T5644 9718-9722 NNP denotes CCR5
T17915 9722-9723 CD denotes −
T5645 9722-9723 NNP denotes −
T17916 9723-9724 NN denotes /
T5646 9723-9724 VBD denotes /
T17917 9724-9725 NN denotes −
T5647 9724-9725 CD denotes −
T17918 9726-9730 NNS denotes Mice
T5648 9726-9730 NNP denotes Mice
T5649 9731-9734 DT denotes The
T5650 9735-9745 NN denotes activation
T5651 9746-9748 IN denotes of
T5652 9749-9754 JJ denotes NF-κB
T5653 9755-9760 NNS denotes plays
T5654 9761-9762 DT denotes a
T5655 9763-9771 JJ denotes critical
T5656 9772-9776 NN denotes role
T5657 9777-9779 IN denotes in
T5658 9780-9786 NN denotes cancer
T5659 9787-9791 NN denotes cell
T5660 9792-9800 NN denotes survival
T5661 9800-9801 , denotes ,
T5662 9802-9812 RB denotes especially
T5663 9813-9821 NN denotes melanoma
T5664 9822-9828 NN denotes cancer
T5665 9829-9834 NNS denotes cells
T5666 9835-9838 CC denotes and
T5667 9839-9841 IN denotes in
T5668 9842-9846 CD denotes CCR5
T5669 9847-9857 NN denotes expression
T17919 9857-9858 . denotes .
T5670 9857-9858 . denotes .
T5671 9859-9861 TO denotes To
T5672 9862-9870 VB denotes evaluate
T5673 9871-9878 IN denotes whether
T5674 9879-9882 DT denotes the
T5675 9883-9888 NN denotes tumor
T5676 9889-9899 NN denotes inhibition
T5677 9900-9903 VBD denotes was
T5678 9904-9911 VBN denotes related
T5679 9912-9916 IN denotes with
T5680 9917-9920 DT denotes the
T5681 9921-9933 NN denotes inactivation
T5682 9934-9936 IN denotes of
T5683 9937-9942 NN denotes NF-κB
T5684 9943-9945 IN denotes in
T5685 9946-9954 NN denotes melanoma
T5686 9954-9955 , denotes ,
T5687 9956-9959 DT denotes the
T5688 9960-9963 NNP denotes DNA
T5689 9964-9971 JJ denotes binding
T5690 9972-9980 NN denotes activity
T5691 9981-9983 IN denotes of
T5692 9984-9989 NN denotes NF-κB
T5693 9990-9993 VBD denotes was
T5694 9994-10004 VBN denotes determined
T5695 10005-10007 IN denotes by
T5696 10008-10023 NN denotes electromobility
T5697 10024-10029 NN denotes shift
T5698 10030-10035 NN denotes assay
T5699 10036-10037 -LRB- denotes (
T5700 10037-10041 NNP denotes EMSA
T5701 10041-10042 -RRB- denotes )
T5702 10043-10045 IN denotes in
T5703 10046-10054 NN denotes melanoma
T5704 10055-10061 NN denotes tissue
T5705 10061-10062 . denotes .
T5706 10063-10066 DT denotes The
T5707 10067-10081 RB denotes constitutively
T5708 10082-10091 VBN denotes activated
T5709 10092-10095 NNP denotes DNA
T5710 10096-10103 JJ denotes binding
T5711 10104-10112 NN denotes activity
T5712 10113-10116 VBD denotes was
T5713 10117-10124 VBN denotes reduced
T5714 10125-10127 IN denotes in
T5715 10128-10131 DT denotes the
T5716 10132-10136 NNP denotes CCR5
T5717 10136-10137 NNP denotes −
T5718 10137-10138 VBD denotes /
T5719 10138-10139 CD denotes −
T5720 10140-10144 NNS denotes mice
T5721 10145-10150 NN denotes tumor
T5722 10151-10157 NN denotes tissue
T5723 10158-10159 -LRB- denotes (
T5724 10159-10165 NN denotes Figure
T5725 10166-10168 NN denotes 2A
T5726 10168-10169 -RRB- denotes )
T5727 10169-10170 . denotes .
T5728 10171-10179 RB denotes Moreover
T5729 10179-10180 , denotes ,
T5730 10181-10184 DT denotes the
T5731 10185-10198 NN denotes translocation
T5732 10199-10201 IN denotes of
T5733 10202-10205 CD denotes p50
T5734 10206-10209 CC denotes and
T5735 10210-10215 CD denotes p-p65
T5736 10216-10220 IN denotes into
T5737 10221-10224 DT denotes the
T5738 10225-10232 NN denotes nucleus
T5739 10233-10240 IN denotes through
T5740 10241-10244 DT denotes the
T5741 10245-10255 NN denotes inhibition
T5742 10256-10258 IN denotes of
T5743 10259-10274 NN denotes phosphorylation
T5744 10275-10277 IN denotes of
T5745 10278-10281 NNP denotes IκB
T5746 10282-10285 VBD denotes was
T5747 10286-10290 RB denotes also
T5748 10291-10300 VBN denotes prevented
T5749 10301-10303 IN denotes in
T5750 10304-10307 DT denotes the
T5751 10308-10313 NN denotes tumor
T5752 10314-10321 NNS denotes tissues
T5753 10322-10324 IN denotes of
T5754 10325-10329 CD denotes CCR5
T5755 10329-10330 CD denotes −
T5756 10330-10331 NN denotes /
T5757 10331-10332 NN denotes −
T5758 10333-10337 NNS denotes mice
T5759 10338-10339 -LRB- denotes (
T5760 10339-10345 NN denotes Figure
T5761 10346-10348 NN denotes 2B
T5762 10348-10349 -RRB- denotes )
T5763 10349-10350 . denotes .
T5764 10351-10369 NNP denotes Immunofluorescence
T5765 10370-10378 NN denotes analysis
T5766 10379-10383 RB denotes also
T5767 10384-10393 VBD denotes confirmed
T5768 10394-10398 IN denotes that
T5769 10399-10402 DT denotes the
T5770 10403-10412 NN denotes intensity
T5771 10413-10415 IN denotes of
T5772 10416-10423 JJ denotes nuclear
T5773 10424-10432 NN denotes staining
T5774 10433-10436 IN denotes for
T5775 10437-10440 CD denotes p50
T5776 10441-10444 VBD denotes had
T5777 10445-10454 VBN denotes decreased
T5778 10455-10457 IN denotes in
T5779 10458-10461 DT denotes the
T5780 10462-10467 NN denotes tumor
T5781 10468-10475 NNS denotes tissues
T5782 10476-10478 IN denotes of
T5783 10479-10483 CD denotes CCR5
T5784 10483-10484 CD denotes −
T5785 10484-10485 NN denotes /
T5786 10485-10486 NN denotes −
T5787 10487-10491 NNS denotes mice
T5788 10492-10493 -LRB- denotes (
T5789 10493-10499 NN denotes Figure
T5790 10500-10502 CD denotes 2C
T5791 10502-10503 -RRB- denotes )
T5792 10503-10504 . denotes .
T17920 10609-10610 DT denotes A
T17921 10610-10611 , denotes ,
T17922 10612-10615 DT denotes The
T17923 10616-10619 NNP denotes DNA
T17924 10620-10627 JJ denotes binding
T17925 10628-10636 NN denotes activity
T17926 10637-10639 IN denotes of
T17927 10640-10645 NN denotes NF-κB
T17928 10646-10649 VBD denotes was
T17929 10650-10660 VBN denotes determined
T17930 10661-10663 IN denotes in
T17931 10664-10667 DT denotes the
T17932 10668-10675 JJ denotes nuclear
T17933 10676-10684 NNS denotes extracts
T17934 10685-10687 IN denotes of
T17935 10688-10691 DT denotes the
T17936 10692-10696 NNP denotes CCR5
T17937 10696-10697 NNP denotes −
T17938 10697-10698 VBD denotes /
T17939 10698-10699 CD denotes −
T17940 10700-10704 NNS denotes mice
T17941 10705-10708 CC denotes and
T17942 10709-10713 NNS denotes CCR5
T17943 10713-10714 VBP denotes +
T17944 10714-10715 CD denotes /
T17945 10715-10716 CD denotes +
T17946 10717-10721 NNS denotes mice
T17947 10722-10727 NN denotes tumor
T17948 10728-10735 NNS denotes tissues
T17949 10736-10738 IN denotes by
T17950 10739-10743 NNP denotes EMSA
T17951 10744-10753 VBD denotes described
T17952 10754-10756 IN denotes in
T17953 10757-10765 NN denotes material
T17954 10766-10769 CC denotes and
T17955 10770-10777 NNS denotes methods
T17956 10777-10778 . denotes .
T17957 10779-10780 NNP denotes B
T17958 10780-10781 , denotes ,
T17959 10782-10792 NNP denotes Expression
T17960 10793-10795 IN denotes of
T17961 10796-10799 CD denotes p50
T17962 10800-10803 CC denotes and
T17963 10804-10807 CD denotes p65
T17964 10808-10823 NN denotes phosphorylation
T17965 10824-10826 IN denotes in
T17966 10827-10834 JJ denotes nuclear
T17967 10835-10843 NNS denotes extracts
T17968 10844-10845 -LRB- denotes (
T17969 10845-10847 NNP denotes NE
T17970 10847-10848 -RRB- denotes )
T17971 10848-10849 , denotes ,
T17972 10850-10853 CC denotes and
T17973 10854-10857 NNP denotes IκB
T17974 10858-10861 CC denotes and
T17975 10862-10865 NNP denotes IκB
T17976 10866-10881 NN denotes phosphorylation
T17977 10882-10884 IN denotes in
T17978 10885-10888 DT denotes the
T17979 10889-10896 NN denotes cytosol
T17980 10897-10898 -LRB- denotes (
T17981 10898-10900 NNP denotes CE
T17982 10900-10901 -RRB- denotes )
T17983 10902-10912 VBN denotes determined
T17984 10913-10915 IN denotes by
T17985 10916-10923 JJ denotes Western
T17986 10924-10932 VBG denotes blotting
T17987 10932-10933 . denotes .
T17988 10934-10935 NNP denotes C
T17989 10935-10936 , denotes ,
T17990 10937-10956 NNP denotes Immunolfluorescence
T17991 10957-10965 NN denotes analysis
T17992 10966-10968 IN denotes of
T17993 10969-10972 CD denotes p50
T17994 10973-10982 VBD denotes confirmed
T17995 10983-10987 IN denotes that
T17996 10988-10991 DT denotes the
T17997 10992-11003 NNS denotes intensities
T17998 11004-11006 IN denotes of
T17999 11007-11014 JJ denotes nuclear
T18000 11015-11023 NN denotes staining
T18001 11024-11027 IN denotes for
T18002 11028-11031 CD denotes p50
T18003 11032-11036 VBD denotes were
T18004 11037-11046 VBN denotes decreased
T18005 11047-11049 IN denotes in
T18006 11050-11053 DT denotes the
T18007 11054-11059 NN denotes tumor
T18008 11060-11067 NNS denotes tissues
T18009 11068-11070 IN denotes of
T18010 11071-11075 CD denotes CCR5
T18011 11075-11076 CD denotes −
T18012 11076-11077 NN denotes /
T18013 11077-11078 NN denotes −
T18014 11079-11083 NNS denotes mice
T18015 11083-11084 . denotes .
T18016 11085-11089 NNS denotes Data
T18017 11090-11093 VBP denotes are
T18018 11094-11099 VBZ denotes means
T18019 11100-11101 NNP denotes ±
T18020 11102-11106 NNP denotes S.D.
T18021 11107-11109 IN denotes of
T18022 11110-11114 CD denotes four
T18023 11115-11127 JJ denotes experimental
T18024 11128-11135 NNS denotes animals
T18025 11135-11136 . denotes .
T18026 11137-11138 SYM denotes *
T18027 11139-11148 VBZ denotes indicates
T18028 11149-11160 JJ denotes significant
T18029 11161-11171 NN denotes difference
T18030 11172-11176 IN denotes from
T18031 11177-11181 CD denotes CCR5
T18032 11181-11182 CD denotes +
T18033 11182-11183 NN denotes /
T18034 11183-11184 NN denotes +
T18035 11185-11189 NNS denotes mice
T18036 11190-11191 -LRB- denotes (
T18037 11191-11192 JJ denotes p
T18038 11192-11193 NN denotes <
T18039 11193-11197 CD denotes 0.05
T18040 11197-11198 -RRB- denotes )
T18041 11198-11199 . denotes .
T18042 11200-11205 NNP denotes Scale
T18043 11206-11209 NN denotes bar
T18044 11210-11219 VBZ denotes indicates
T18045 11220-11222 CD denotes 50
T18046 11223-11225 NN denotes µm
T18047 11225-11226 . denotes .
T18556 11228-11237 NNP denotes Induction
T6287 11228-11237 NNP denotes Induction
T18557 11238-11240 IN denotes of
T6288 11238-11240 IN denotes of
T18558 11241-11250 JJ denotes Apoptotic
T6289 11241-11250 NNP denotes Apoptotic
T18559 11251-11255 NN denotes Cell
T6290 11251-11255 NNP denotes Cell
T18560 11256-11261 NN denotes Death
T6291 11256-11261 NNP denotes Death
T6292 11262-11265 CC denotes and
T6293 11266-11276 NNP denotes Inhibition
T6294 11277-11279 IN denotes of
T6295 11280-11283 DT denotes the
T6296 11284-11294 NN denotes Expression
T6297 11295-11297 IN denotes of
T6298 11298-11312 JJ denotes Anti-apoptotic
T6299 11313-11321 NNPS denotes Proteins
T6300 11322-11324 IN denotes in
T6301 11325-11329 NNP denotes CCR5
T6302 11329-11330 NNP denotes −
T6303 11330-11331 VBD denotes /
T6304 11331-11332 CD denotes −
T6326 11333-11337 NNP denotes Mice
T6327 11338-11340 TO denotes To
T6328 11341-11344 VB denotes see
T6329 11345-11352 IN denotes whether
T6330 11353-11363 NN denotes inhibition
T6331 11364-11366 IN denotes of
T6332 11367-11372 JJ denotes NF-κB
T6333 11373-11381 NN denotes activity
T6334 11382-11389 NNS denotes results
T6335 11390-11392 IN denotes in
T6336 11393-11396 DT denotes the
T6337 11397-11406 NN denotes induction
T6338 11407-11409 IN denotes of
T6339 11410-11419 JJ denotes apoptotic
T6340 11420-11424 NN denotes cell
T6341 11425-11430 NN denotes death
T6342 11431-11434 CC denotes and
T6343 11435-11445 NN denotes expression
T6344 11446-11448 IN denotes of
T6345 11449-11454 JJ denotes NF-κB
T6346 11455-11461 NN denotes target
T6347 11462-11471 JJ denotes apoptotic
T6348 11472-11476 NN denotes cell
T6349 11477-11482 NN denotes death
T6350 11483-11493 JJ denotes regulatory
T6351 11494-11501 NN denotes protein
T6352 11501-11502 , denotes ,
T6353 11503-11506 DT denotes the
T6354 11507-11513 NNS denotes levels
T6355 11514-11516 IN denotes of
T6356 11517-11526 JJ denotes apoptotic
T6357 11527-11531 NN denotes cell
T6358 11532-11537 NN denotes death
T6359 11538-11541 CC denotes and
T6360 11542-11552 NN denotes expression
T6361 11553-11555 IN denotes of
T6362 11556-11565 JJ denotes apoptotic
T6363 11566-11570 NN denotes cell
T6364 11571-11576 NN denotes death
T6365 11577-11587 JJ denotes regulatory
T6366 11588-11596 NNS denotes proteins
T6367 11597-11601 VBD denotes were
T6368 11602-11610 VBN denotes assessed
T6369 11610-11611 . denotes .
T6370 11612-11621 JJ denotes Apoptotic
T6371 11622-11626 NN denotes cell
T6372 11627-11632 NN denotes death
T6373 11633-11635 IN denotes in
T6374 11636-11639 DT denotes the
T6375 11640-11645 NN denotes tumor
T6376 11646-11654 NNS denotes sections
T6377 11655-11659 VBD denotes were
T6378 11660-11669 VBN denotes evaluated
T6379 11670-11672 IN denotes in
T6380 11673-11676 DT denotes the
T6381 11677-11681 NNP denotes CCR5
T6382 11681-11682 NNP denotes +
T6383 11682-11683 VBD denotes /
T6384 11683-11684 CD denotes +
T6385 11685-11688 CC denotes and
T6386 11689-11693 CD denotes CCR5
T6387 11693-11694 CD denotes −
T6388 11694-11695 NN denotes /
T6389 11695-11696 NN denotes −
T6390 11697-11701 NNS denotes mice
T6391 11702-11706 WDT denotes that
T6416 11707-11711 VBD denotes were
T6417 11712-11722 VBN denotes inoculated
T6418 11723-11727 IN denotes with
T6419 11728-11736 NN denotes melanoma
T6420 11737-11742 NNS denotes cells
T6421 11742-11743 . denotes .
T6422 11744-11749 NNP denotes TUNEL
T6423 11750-11758 VBG denotes staining
T6424 11759-11767 VBD denotes revealed
T6425 11768-11769 DT denotes a
T6426 11770-11776 JJR denotes higher
T6427 11777-11786 NN denotes frequency
T6428 11787-11789 IN denotes of
T6429 11790-11799 JJ denotes apoptotic
T6430 11800-11804 NN denotes cell
T6431 11805-11810 NN denotes death
T6432 11811-11813 IN denotes in
T6433 11814-11817 DT denotes the
T6434 11818-11823 NN denotes tumor
T6435 11824-11831 NNS denotes tissues
T6436 11832-11834 IN denotes of
T6437 11835-11838 DT denotes the
T6438 11839-11843 NNP denotes CCR5
T6439 11843-11844 NNP denotes −
T6440 11844-11845 VBD denotes /
T6441 11845-11846 CD denotes −
T6442 11847-11851 NNS denotes mice
T6443 11852-11856 IN denotes than
T6444 11857-11861 DT denotes that
T6445 11862-11864 IN denotes of
T6446 11865-11868 DT denotes the
T6447 11869-11873 NNP denotes CCR5
T6448 11873-11874 NNP denotes +
T6449 11874-11875 VBD denotes /
T6450 11875-11876 CD denotes +
T6451 11877-11881 NNS denotes mice
T6452 11882-11883 -LRB- denotes (
T6453 11883-11889 NN denotes Figure
T6454 11890-11892 NN denotes 3A
T6455 11892-11893 -RRB- denotes )
T6456 11893-11894 . denotes .
T6457 11895-11914 NNP denotes Immunohistochemical
T6458 11915-11918 CC denotes and
T6459 11919-11937 NN denotes immunofluorescence
T6460 11938-11944 VBD denotes showed
T6461 11945-11949 IN denotes that
T6462 11950-11954 JJ denotes high
T6463 11955-11961 NNS denotes levels
T6464 11962-11964 IN denotes of
T6465 11965-11972 JJ denotes cleaved
T6466 11973-11982 JJ denotes caspase-3
T6467 11983-11986 CC denotes and
T6468 11987-11990 NNP denotes Bax
T6469 11991-11995 VBD denotes were
T6470 11996-12001 VBN denotes found
T6471 12002-12006 RBR denotes more
T6472 12007-12017 RB denotes frequently
T6473 12018-12020 IN denotes in
T6474 12021-12024 DT denotes the
T6475 12025-12029 NNP denotes CCR5
T6476 12029-12030 NNP denotes −
T6477 12030-12031 VBD denotes /
T6478 12031-12032 CD denotes −
T6479 12033-12037 NNS denotes mice
T6480 12038-12042 IN denotes than
T6481 12043-12045 IN denotes in
T6482 12046-12049 DT denotes the
T6483 12050-12054 NNP denotes CCR5
T6484 12054-12055 NNP denotes +
T6485 12055-12056 VBD denotes /
T6486 12056-12057 CD denotes +
T6487 12058-12062 NNS denotes mice
T6488 12063-12064 -LRB- denotes (
T6489 12064-12070 NNP denotes Figure
T6490 12071-12073 NNP denotes 3B
T6491 12074-12077 CC denotes and
T6492 12078-12080 NNP denotes 3C
T6493 12080-12081 -RRB- denotes )
T6494 12081-12082 . denotes .
T6495 12083-12093 JJ denotes Consistent
T6496 12094-12098 IN denotes with
T6497 12099-12102 DT denotes the
T6498 12103-12122 JJ denotes immunohistochemical
T6499 12123-12127 NNS denotes data
T6500 12127-12128 , denotes ,
T6501 12129-12136 JJ denotes Western
T6502 12137-12141 NN denotes blot
T6503 12142-12150 NN denotes analysis
T6504 12151-12153 IN denotes of
T6505 12154-12159 NN denotes tumor
T6506 12160-12168 NNS denotes proteins
T6507 12169-12175 VBD denotes showed
T6508 12176-12183 JJR denotes greater
T6509 12184-12193 VBD denotes increased
T6510 12194-12200 NNS denotes levels
T6511 12201-12203 IN denotes of
T6512 12204-12211 JJ denotes cleaved
T6513 12212-12221 JJ denotes caspase-3
T6514 12221-12222 , denotes ,
T6515 12223-12230 JJ denotes cleaved
T6516 12231-12240 JJ denotes caspase-9
T6517 12240-12241 , denotes ,
T6518 12242-12249 JJ denotes cleaved
T6519 12250-12254 NNP denotes PARP
T6520 12255-12258 CC denotes and
T6521 12259-12262 NNP denotes Bax
T6522 12262-12263 , denotes ,
T6523 12264-12271 IN denotes whereas
T6524 12272-12275 DT denotes the
T6525 12276-12282 NNS denotes levels
T6526 12283-12285 IN denotes of
T6527 12286-12291 NN denotes Bcl-2
T6528 12292-12295 CC denotes and
T6529 12296-12302 NN denotes C-IAP1
T6530 12303-12307 VBD denotes were
T6531 12308-12321 RB denotes significantly
T6532 12322-12331 VBN denotes decreased
T6533 12332-12334 IN denotes in
T6534 12335-12339 CD denotes CCR5
T6535 12339-12340 CD denotes −
T6536 12340-12341 NN denotes /
T6537 12341-12342 NN denotes −
T6538 12343-12347 NNS denotes mice
T6539 12348-12355 NNS denotes tissues
T6540 12356-12357 -LRB- denotes (
T6541 12357-12363 NN denotes Figure
T6542 12364-12366 CD denotes 3D
T6543 12366-12367 -RRB- denotes )
T6544 12367-12368 . denotes .
T18561 12447-12449 IN denotes in
T18562 12450-12455 NN denotes tumor
T18563 12456-12463 NNS denotes tissues
T18564 12464-12466 IN denotes of
T18565 12467-12471 CD denotes CCR5
T18566 12472-12473 CD denotes −
T18567 12473-12474 NN denotes /
T18568 12474-12475 NN denotes −
T18569 12476-12480 NNS denotes mice
T18570 12480-12481 . denotes .
T18571 12482-12483 DT denotes A
T18572 12483-12484 , denotes ,
T18573 12485-12494 JJ denotes Apoptotic
T18574 12495-12500 NNS denotes cells
T18575 12501-12503 IN denotes in
T18576 12504-12509 NN denotes tumor
T18577 12510-12518 NNS denotes sections
T18578 12519-12523 VBD denotes were
T18579 12524-12532 VBN denotes examined
T18580 12533-12535 IN denotes by
T18581 12536-12548 NN denotes fluorescence
T18582 12549-12559 NN denotes microscopy
T18583 12560-12565 IN denotes after
T18584 12566-12570 NNP denotes DAPI
T18585 12571-12574 CC denotes and
T18586 12575-12580 NNP denotes TUNEL
T18587 12581-12589 VBG denotes staining
T18588 12590-12592 IN denotes as
T18589 12593-12602 VBN denotes described
T18590 12603-12605 IN denotes in
T18591 12606-12614 NN denotes material
T18592 12615-12618 CC denotes and
T18593 12619-12626 NNS denotes methods
T18594 12626-12627 . denotes .
T18595 12628-12631 DT denotes The
T18596 12632-12641 JJ denotes apoptotic
T18597 12642-12647 NN denotes index
T18598 12648-12651 VBD denotes was
T18599 12652-12662 VBN denotes determined
T18600 12663-12665 IN denotes as
T18601 12666-12669 DT denotes the
T18602 12670-12676 NN denotes number
T18603 12677-12679 IN denotes of
T18604 12680-12692 JJ denotes DAPI-stained
T18605 12692-12693 , denotes ,
T18606 12694-12708 JJ denotes TUNEL-positive
T18607 12709-12714 NNS denotes cells
T18608 12715-12719 WDT denotes that
T18609 12720-12724 VBD denotes were
T18610 12725-12732 VBN denotes counted
T18611 12732-12733 . denotes .
T18612 12734-12740 NNS denotes Values
T18613 12741-12744 VBP denotes are
T18614 12745-12748 DT denotes the
T18615 12749-12753 JJ denotes mean
T18616 12754-12755 NN denotes ±
T18617 12756-12760 NNP denotes S.D.
T18618 12761-12763 IN denotes of
T18619 12764-12768 CD denotes four
T18620 12769-12781 JJ denotes experimental
T18621 12782-12789 NNS denotes animals
T18622 12789-12790 . denotes .
T18623 12791-12792 SYM denotes *
T18624 12793-12802 VBZ denotes indicates
T18625 12803-12816 RB denotes statistically
T18626 12817-12828 JJ denotes significant
T18627 12829-12840 NNS denotes differences
T18628 12841-12845 IN denotes from
T18629 12846-12850 CD denotes CCR5
T18630 12850-12851 CD denotes +
T18631 12851-12852 NN denotes /
T18632 12852-12853 NN denotes +
T18633 12854-12858 NNS denotes mice
T18634 12858-12859 . denotes .
T18635 12860-12865 NNP denotes Scale
T18636 12866-12869 NN denotes bar
T18637 12870-12879 VBZ denotes indicates
T18638 12880-12882 CD denotes 50
T18639 12883-12885 NN denotes µm
T18640 12885-12886 . denotes .
T18641 12887-12888 NNP denotes B
T18642 12889-12892 CC denotes and
T18643 12893-12894 NNP denotes C
T18644 12894-12895 , denotes ,
T18645 12896-12905 NNP denotes Apoptotic
T18646 12906-12913 NN denotes protein
T18647 12914-12915 -LRB- denotes (
T18648 12915-12922 VBN denotes cleaved
T18649 12923-12932 JJ denotes caspase-3
T18650 12933-12936 CC denotes and
T18651 12937-12940 NNP denotes Bax
T18652 12940-12941 -RRB- denotes )
T18653 12942-12944 IN denotes in
T18654 12945-12950 NN denotes tumor
T18655 12951-12959 NNS denotes sections
T18656 12960-12964 VBD denotes were
T18657 12965-12973 VBN denotes detected
T18658 12974-12976 IN denotes by
T18659 12977-12995 NN denotes immunofluorescence
T18660 12996-13001 NN denotes assay
T18661 13001-13002 . denotes .
T18662 13003-13006 DT denotes The
T18663 13007-13015 JJ denotes reactive
T18664 13016-13020 NN denotes cell
T18665 13021-13027 NN denotes number
T18666 13028-13031 VBD denotes was
T18667 13032-13042 VBN denotes determined
T18668 13043-13045 IN denotes as
T18669 13046-13049 DT denotes the
T18670 13050-13056 NN denotes number
T18671 13057-13059 IN denotes of
T18672 13060-13072 JJ denotes DAPI-stained
T18673 13072-13073 , denotes ,
T18674 13074-13082 JJ denotes Specific
T18675 13083-13091 NN denotes antibody
T18676 13092-13093 -LRB- denotes (
T18677 13093-13100 VBN denotes cleaved
T18678 13101-13110 JJ denotes caspase-3
T18679 13111-13114 CC denotes and
T18680 13115-13118 NNP denotes Bax
T18681 13118-13119 -RRB- denotes )
T18682 13119-13120 : denotes -
T18683 13120-13128 JJ denotes positive
T18684 13129-13134 NNS denotes cells
T18685 13135-13139 WDT denotes that
T18686 13140-13144 VBD denotes were
T18687 13145-13152 VBN denotes counted
T18688 13152-13153 . denotes .
T18689 13154-13160 NNS denotes Values
T18690 13161-13164 VBP denotes are
T18691 13165-13168 DT denotes the
T18692 13169-13173 JJ denotes mean
T18693 13174-13175 NN denotes ±
T18694 13176-13180 NNP denotes S.D.
T18695 13181-13183 IN denotes of
T18696 13184-13188 CD denotes four
T18697 13189-13201 JJ denotes experimental
T18698 13202-13209 NNS denotes animals
T18699 13209-13210 . denotes .
T18700 13211-13212 SYM denotes *
T18701 13213-13222 VBZ denotes indicates
T18702 13223-13236 RB denotes statistically
T18703 13237-13248 JJ denotes significant
T18704 13249-13260 NNS denotes differences
T18705 13261-13265 IN denotes from
T18706 13266-13270 CD denotes CCR5
T18707 13270-13271 CD denotes +
T18708 13271-13272 NN denotes /
T18709 13272-13273 NN denotes +
T18710 13274-13278 NNS denotes mice
T18711 13278-13279 . denotes .
T18712 13280-13285 NNP denotes Scale
T18713 13286-13289 NN denotes bar
T18714 13290-13299 VBZ denotes indicates
T18715 13300-13302 CD denotes 50
T18716 13303-13305 NN denotes µm
T18717 13305-13306 . denotes .
T18718 13307-13308 NNP denotes D
T18719 13308-13309 , denotes ,
T18720 13310-13313 DT denotes The
T18721 13314-13324 NN denotes expression
T18722 13325-13327 IN denotes of
T18723 13328-13337 JJ denotes apoptotic
T18724 13338-13346 NNS denotes proteins
T18725 13347-13350 VBD denotes was
T18726 13351-13359 VBN denotes detected
T18727 13360-13362 IN denotes by
T18728 13363-13370 JJ denotes Western
T18729 13371-13379 VBG denotes blotting
T18730 13380-13385 VBG denotes using
T18731 13386-13394 JJ denotes specific
T18732 13395-13405 NNS denotes antibodies
T18733 13405-13406 : denotes ;
T18734 13407-13414 VBD denotes cleaved
T18735 13415-13424 JJ denotes caspase-3
T18736 13424-13425 , denotes ,
T18737 13426-13433 JJ denotes cleaved
T18738 13434-13443 JJ denotes caspase-9
T18739 13443-13444 , denotes ,
T18740 13445-13452 JJ denotes cleaved
T18741 13453-13457 NNP denotes PARP
T18742 13457-13458 , denotes ,
T18743 13459-13462 NNP denotes Bax
T18744 13462-13463 , denotes ,
T18745 13464-13469 NNP denotes Bcl-2
T18746 13470-13473 CC denotes and
T18747 13474-13480 NNP denotes c-IAP1
T18748 13481-13483 IN denotes in
T18749 13484-13487 DT denotes the
T18750 13488-13493 NN denotes tumor
T18751 13494-13501 NNS denotes tissues
T18752 13501-13502 . denotes .
T18753 13503-13506 DT denotes The
T18754 13507-13514 JJ denotes β-actin
T18755 13515-13522 NN denotes protein
T18756 13523-13526 VBD denotes was
T18757 13527-13531 VBN denotes used
T18758 13532-13534 IN denotes as
T18759 13535-13537 DT denotes an
T18760 13538-13546 JJ denotes internal
T18761 13547-13554 NN denotes control
T18762 13554-13555 . denotes .
T18763 13556-13560 DT denotes Each
T18764 13561-13565 NN denotes band
T18765 13566-13568 VBZ denotes is
T18766 13569-13583 NN denotes representative
T18767 13584-13586 IN denotes of
T18768 13587-13592 CD denotes three
T18769 13593-13604 JJ denotes independent
T18770 13605-13617 JJ denotes experimental
T18771 13618-13625 NNS denotes results
T18772 13625-13626 . denotes .
T18773 13627-13631 NNS denotes Data
T18774 13632-13635 VBP denotes are
T18775 13636-13641 VBZ denotes means
T18776 13642-13643 NNP denotes ±
T18777 13644-13648 NNP denotes S.D.
T18778 13649-13651 IN denotes of
T18779 13652-13657 CD denotes three
T18780 13658-13670 JJ denotes experimental
T18781 13671-13678 NNS denotes animals
T18782 13678-13679 . denotes .
T18783 13680-13681 SYM denotes *
T18784 13682-13691 VBZ denotes indicates
T18785 13692-13703 JJ denotes significant
T18786 13704-13714 NN denotes difference
T18787 13715-13719 IN denotes from
T18788 13720-13724 CD denotes CCR5
T18789 13724-13725 CD denotes +
T18790 13725-13726 NN denotes /
T18791 13726-13727 NN denotes +
T18792 13728-13732 NNS denotes mice
T18793 13733-13734 -LRB- denotes (
T18794 13734-13735 JJ denotes p
T18795 13735-13736 NN denotes <
T18796 13736-13740 CD denotes 0.05
T18797 13740-13741 -RRB- denotes )
T18798 13741-13742 . denotes .
T19298 13744-13756 NN denotes Upregulation
T6876 13744-13756 NN denotes Upregulation
T19299 13757-13759 IN denotes of
T6877 13757-13759 IN denotes of
T19300 13760-13766 NN denotes IL-1Ra
T6878 13760-13766 NN denotes IL-1Ra
T19301 13767-13769 IN denotes in
T6879 13767-13769 IN denotes in
T19302 13770-13773 DT denotes the
T6880 13770-13773 DT denotes the
T19303 13774-13779 NN denotes Tumor
T6881 13774-13779 NNP denotes Tumor
T19304 13780-13783 CC denotes and
T6882 13780-13783 CC denotes and
T19305 13784-13790 NN denotes Spleen
T6883 13784-13790 NNP denotes Spleen
T19306 13791-13793 IN denotes of
T6884 13791-13793 IN denotes of
T19307 13794-13798 CD denotes CCR5
T6885 13794-13798 NNP denotes CCR5
T19308 13798-13799 CD denotes −
T6886 13798-13799 NNP denotes −
T19309 13799-13800 NN denotes /
T6887 13799-13800 VBD denotes /
T19310 13800-13801 NN denotes −
T6888 13800-13801 CD denotes −
T19311 13802-13806 NNS denotes Mice
T6889 13802-13806 NNP denotes Mice
T6890 13807-13809 TO denotes To
T6891 13810-13821 VB denotes investigate
T6892 13822-13825 DT denotes the
T6893 13826-13836 NN denotes difference
T6894 13837-13839 IN denotes in
T6895 13840-13843 DT denotes the
T6896 13844-13852 NN denotes cytokine
T6897 13853-13859 NNS denotes levels
T6898 13860-13867 IN denotes between
T6899 13868-13871 DT denotes the
T6900 13872-13877 NN denotes tumor
T6901 13878-13881 CC denotes and
T6902 13882-13888 NN denotes spleen
T6903 13889-13896 NNS denotes tissues
T6904 13897-13899 IN denotes of
T6905 13900-13903 DT denotes the
T6906 13904-13908 NNP denotes CCR5
T6907 13908-13909 NNP denotes +
T6908 13909-13910 VBD denotes /
T6909 13910-13911 CD denotes +
T6910 13912-13915 CC denotes and
T6911 13916-13920 CD denotes CCR5
T6912 13920-13921 CD denotes −
T6913 13921-13922 NN denotes /
T6914 13922-13923 NN denotes −
T6915 13924-13928 NNS denotes mice
T6916 13928-13929 , denotes ,
T6917 13930-13932 PRP denotes we
T6918 13933-13942 VBD denotes conducted
T6919 13943-13944 DT denotes a
T6920 13945-13953 JJ denotes cytokine
T6921 13954-13959 NN denotes array
T6922 13960-13965 NN denotes assay
T6923 13966-13971 VBG denotes using
T6924 13972-13973 DT denotes a
T6925 13974-13979 NNP denotes Mouse
T6926 13980-13988 NNP denotes Proteome
T6927 13989-13994 NNP denotes Array
T6928 13995-13996 -LRB- denotes (
T6929 13996-14002 NNP denotes Figure
T6930 14003-14005 NNP denotes 4A
T6931 14005-14006 -RRB- denotes )
T19312 14006-14007 . denotes .
T6932 14006-14007 . denotes .
T6933 14008-14013 IN denotes Among
T6934 14014-14016 CD denotes 40
T6935 14017-14023 VBN denotes tested
T6936 14024-14033 NNS denotes cytokines
T6937 14033-14034 , denotes ,
T6938 14035-14038 DT denotes the
T6939 14039-14045 NNS denotes levels
T6940 14046-14048 IN denotes of
T6941 14049-14055 NN denotes IL-1Ra
T6942 14055-14056 , denotes ,
T6943 14057-14060 NNP denotes MIG
T6944 14060-14061 , denotes ,
T6945 14062-14068 NNP denotes MIP-1α
T6946 14069-14078 VBD denotes increased
T6947 14079-14084 IN denotes about
T6948 14085-14088 CD denotes 686
T6949 14088-14089 , denotes ,
T6950 14090-14091 CD denotes 9
T6951 14092-14095 CC denotes and
T6952 14096-14103 JJ denotes 25-fold
T6953 14104-14116 RB denotes respectively
T6954 14116-14117 , denotes ,
T6955 14118-14120 IN denotes in
T6956 14121-14125 CD denotes CCR5
T6957 14125-14126 CD denotes −
T6958 14126-14127 NN denotes /
T6959 14127-14128 NN denotes −
T6960 14129-14133 NNS denotes mice
T6961 14134-14142 VBN denotes compared
T6962 14143-14145 TO denotes to
T6963 14146-14150 CD denotes CCR5
T6986 14150-14151 CD denotes +
T6987 14151-14152 NN denotes /
T6988 14152-14153 NN denotes +
T6989 14154-14158 NNS denotes mice
T6990 14158-14159 . denotes .
T6991 14160-14165 VBG denotes Using
T6992 14166-14170 DT denotes this
T6993 14171-14180 NN denotes technique
T6994 14180-14181 , denotes ,
T6995 14182-14184 DT denotes no
T6996 14185-14190 JJ denotes other
T6997 14191-14200 NNS denotes cytokines
T6998 14201-14205 VBD denotes were
T6999 14206-14211 VBN denotes found
T7000 14212-14214 TO denotes to
T7001 14215-14217 VB denotes be
T7002 14218-14227 JJ denotes different
T7003 14228-14235 IN denotes between
T7004 14236-14239 DT denotes the
T7005 14240-14244 NNP denotes CCR5
T7006 14244-14245 NNP denotes −
T7007 14245-14246 VBD denotes /
T7008 14246-14247 CD denotes −
T7009 14248-14252 NNS denotes mice
T7010 14253-14256 CC denotes and
T7011 14257-14260 DT denotes the
T7012 14261-14265 NNP denotes CCR5
T7013 14265-14266 NNP denotes +
T7014 14266-14267 VBD denotes /
T7015 14267-14268 CD denotes +
T7016 14269-14273 NNS denotes mice
T7017 14274-14275 -LRB- denotes (
T7018 14275-14281 NN denotes Figure
T7019 14282-14284 NN denotes 4B
T7020 14284-14285 -RRB- denotes )
T7021 14285-14286 . denotes .
T7022 14287-14294 JJ denotes Similar
T7023 14295-14302 JJ denotes altered
T7024 14303-14311 NN denotes cytokine
T7025 14312-14318 NNS denotes levels
T7026 14319-14323 VBD denotes were
T7027 14324-14329 VBN denotes found
T7028 14330-14332 IN denotes in
T7029 14333-14336 DT denotes the
T7030 14337-14344 NNS denotes spleens
T7031 14345-14347 IN denotes of
T7032 14348-14352 CD denotes CCR5
T7033 14352-14353 CD denotes −
T7034 14353-14354 NN denotes /
T7035 14354-14355 NN denotes −
T7036 14356-14360 NNS denotes mice
T7037 14361-14362 -LRB- denotes (
T7038 14362-14368 NN denotes Figure
T7039 14369-14371 NN denotes 4C
T7040 14371-14372 -RRB- denotes )
T7041 14372-14373 . denotes .
T7042 14374-14379 IN denotes Since
T7043 14380-14383 DT denotes the
T7044 14384-14390 JJ denotes IL-1Ra
T7045 14391-14396 NN denotes level
T7046 14397-14400 VBD denotes was
T7047 14401-14404 DT denotes the
T7048 14405-14409 RBS denotes most
T7049 14410-14423 RB denotes significantly
T7050 14424-14432 JJ denotes elevated
T7051 14432-14433 , denotes ,
T7052 14434-14437 DT denotes the
T7053 14438-14448 NN denotes expression
T7054 14449-14451 IN denotes of
T7055 14452-14458 NN denotes IL-1Ra
T7056 14459-14461 IN denotes in
T7057 14462-14467 NN denotes tumor
T7058 14468-14471 CC denotes and
T7059 14472-14478 NN denotes spleen
T7060 14479-14486 NNS denotes tissues
T7061 14487-14490 VBD denotes was
T7062 14491-14499 VBN denotes analyzed
T7063 14500-14502 IN denotes by
T7064 14503-14521 NN denotes immunofluorescence
T7065 14522-14525 CC denotes and
T7066 14526-14533 JJ denotes western
T7067 14534-14542 VBG denotes blotting
T7068 14542-14543 . denotes .
T7069 14544-14547 DT denotes The
T7070 14548-14558 NN denotes expression
T7071 14559-14561 IN denotes of
T7072 14562-14568 NN denotes IL-1Ra
T7073 14569-14572 VBD denotes was
T7074 14573-14584 VBN denotes upregulated
T7075 14585-14587 IN denotes in
T7076 14588-14593 NN denotes tumor
T7077 14594-14597 CC denotes and
T7078 14598-14604 NN denotes spleen
T7079 14605-14612 NNS denotes tissues
T7080 14613-14615 IN denotes of
T7081 14616-14619 DT denotes the
T7082 14620-14624 NNP denotes CCR5
T7083 14624-14625 NNP denotes −
T7084 14625-14626 VBD denotes /
T7085 14626-14627 CD denotes −
T7086 14628-14632 NNS denotes mice
T7087 14633-14634 -LRB- denotes (
T7088 14634-14640 NN denotes Figure
T7089 14641-14645 NN denotes 4D-G
T7090 14645-14646 -RRB- denotes )
T7091 14646-14647 . denotes .
T19313 14756-14757 DT denotes A
T19314 14757-14758 , denotes ,
T19315 14759-14765 NNP denotes Figure
T19316 14766-14768 NNP denotes 4A
T19317 14769-14778 VBZ denotes indicates
T19318 14779-14784 NN denotes mouse
T19319 14785-14793 NN denotes cytokine
T19320 14794-14799 NN denotes array
T19321 14800-14805 NN denotes panel
T19322 14806-14817 VBZ denotes coordinates
T19323 14817-14818 . denotes .
T19324 14819-14833 JJ denotes Nitrocellulose
T19325 14834-14843 NNS denotes membranes
T19326 14844-14851 VBP denotes contain
T19327 14852-14854 CD denotes 40
T19328 14855-14864 JJ denotes different
T19329 14865-14878 JJ denotes anti-cytokine
T19330 14879-14889 NNS denotes antibodies
T19331 14890-14897 VBN denotes printed
T19332 14898-14900 IN denotes in
T19333 14901-14910 VB denotes duplicate
T19334 14910-14911 . denotes .
T19335 14912-14913 NNP denotes B
T19336 14913-14914 , denotes ,
T19337 14915-14920 NNP denotes Mouse
T19338 14921-14929 NN denotes cytokine
T19339 14930-14935 NN denotes array
T19340 14936-14941 NN denotes panel
T19341 14942-14950 VBP denotes indicate
T19342 14951-14954 DT denotes the
T19343 14955-14963 NN denotes cytokine
T19344 14964-14974 NN denotes expression
T19345 14975-14985 NN denotes difference
T19346 14986-14988 IN denotes in
T19347 14989-14994 NN denotes tumor
T19348 14995-15002 NNS denotes tissues
T19349 15003-15005 IN denotes of
T19350 15006-15010 CD denotes CCR5
T19351 15010-15011 CD denotes +
T19352 15011-15012 NN denotes /
T19353 15012-15013 NN denotes +
T19354 15014-15018 NNS denotes mice
T19355 15019-15022 CC denotes and
T19356 15023-15027 NNS denotes CCR5
T19357 15027-15028 VBP denotes −
T19358 15028-15029 CD denotes /
T19359 15029-15030 CD denotes −
T19360 15031-15035 NNS denotes mice
T19361 15035-15036 , denotes ,
T19362 15037-15047 RB denotes especially
T19363 15048-15054 JJ denotes IL-1Ra
T19364 15054-15055 . denotes .
T19365 15056-15070 NNP denotes Representative
T19366 15071-15075 NN denotes blot
T19367 15076-15080 IN denotes from
T19368 15081-15086 CD denotes three
T19369 15087-15098 JJ denotes independent
T19370 15099-15110 NNS denotes experiments
T19371 15111-15113 VBZ denotes is
T19372 15114-15119 VBN denotes shown
T19373 15119-15120 . denotes .
T19374 15121-15129 JJ denotes Positive
T19375 15130-15138 NNS denotes controls
T19376 15139-15143 VBP denotes show
T19377 15144-15147 DT denotes the
T19378 15148-15160 NN denotes manufacturer
T19379 15163-15171 JJ denotes internal
T19380 15172-15180 JJ denotes positive
T19381 15181-15188 NN denotes control
T19382 15189-15196 NNS denotes samples
T19383 15197-15199 IN denotes on
T19384 15200-15203 DT denotes the
T19385 15204-15212 NN denotes membrane
T19386 15212-15213 . denotes .
T19387 15214-15215 NNP denotes C
T19388 15215-15216 , denotes ,
T19389 15217-15224 NNP denotes Protein
T19390 15225-15238 NNS denotes immune-arrays
T19391 15239-15243 VBD denotes were
T19392 15244-15253 VBN denotes performed
T19393 15254-15259 VBG denotes using
T19394 15260-15265 NNP denotes Mouse
T19395 15266-15274 NN denotes cytokine
T19396 15275-15280 NN denotes array
T19397 15281-15283 IN denotes in
T19398 15284-15290 JJ denotes spleen
T19399 15291-15298 NNS denotes tissues
T19400 15298-15299 . denotes .
T19401 15300-15305 EX denotes There
T19402 15306-15310 VBD denotes were
T19403 15311-15322 NNS denotes differences
T19404 15323-15325 IN denotes in
T19405 15326-15335 NNS denotes cytokines
T19406 15336-15343 IN denotes between
T19407 15344-15348 CD denotes CCR5
T19408 15348-15349 CD denotes +
T19409 15349-15350 NN denotes /
T19410 15350-15351 NN denotes +
T19411 15352-15356 NNS denotes mice
T19412 15357-15360 CC denotes and
T19413 15361-15365 NNS denotes CCR5
T19414 15365-15366 VBP denotes −
T19415 15366-15367 CD denotes /
T19416 15367-15368 CD denotes −
T19417 15369-15373 NNS denotes mice
T19418 15373-15374 , denotes ,
T19419 15375-15385 RB denotes especially
T19420 15386-15392 JJ denotes IL-1Ra
T19421 15392-15393 . denotes .
T19422 15394-15408 NNP denotes Representative
T19423 15409-15413 NN denotes blot
T19424 15414-15418 IN denotes from
T19425 15419-15424 CD denotes three
T19426 15425-15436 JJ denotes independent
T19427 15437-15448 NNS denotes experiments
T19428 15449-15451 VBZ denotes is
T19429 15452-15457 VBN denotes shown
T19430 15457-15458 . denotes .
T19431 15459-15467 JJ denotes Positive
T19432 15468-15476 NNS denotes controls
T19433 15477-15481 VBP denotes show
T19434 15482-15485 DT denotes the
T19435 15486-15498 NN denotes manufacturer
T19436 15501-15509 JJ denotes internal
T19437 15510-15518 JJ denotes positive
T19438 15519-15526 NN denotes control
T19439 15527-15534 NNS denotes samples
T19440 15535-15537 IN denotes on
T19441 15538-15541 DT denotes the
T19442 15542-15550 NN denotes membrane
T19443 15550-15551 . denotes .
T19444 15552-15553 NNP denotes D
T19445 15554-15557 CC denotes and
T19446 15558-15559 NNP denotes E
T19447 15559-15560 , denotes ,
T19448 15561-15580 NNP denotes Immunolfluorescence
T19449 15581-15589 NN denotes analysis
T19450 15590-15593 VBD denotes was
T19451 15594-15598 VBN denotes used
T19452 15599-15601 TO denotes to
T19453 15602-15611 VB denotes determine
T19454 15612-15615 DT denotes the
T19455 15616-15626 NN denotes expression
T19456 15627-15633 NNS denotes levels
T19457 15634-15636 IN denotes of
T19458 15637-15643 NN denotes IL-1Ra
T19459 15644-15646 IN denotes in
T19460 15647-15652 NN denotes tumor
T19461 15653-15656 CC denotes and
T19462 15657-15663 NN denotes spleen
T19463 15664-15671 NNS denotes tissues
T19464 15671-15672 . denotes .
T19465 15673-15676 DT denotes The
T19466 15677-15685 JJ denotes reactive
T19467 15686-15690 NN denotes cell
T19468 15691-15697 NN denotes number
T19469 15698-15701 VBD denotes was
T19470 15702-15712 VBN denotes determined
T19471 15713-15715 IN denotes as
T19472 15716-15719 DT denotes the
T19473 15720-15726 NN denotes number
T19474 15727-15729 IN denotes of
T19475 15730-15742 JJ denotes DAPI-stained
T19476 15742-15743 , denotes ,
T19477 15744-15750 JJ denotes IL-1Ra
T19478 15751-15768 JJ denotes antibody-positive
T19479 15769-15774 NNS denotes cells
T19480 15775-15779 WDT denotes that
T19481 15780-15784 VBD denotes were
T19482 15785-15792 VBN denotes counted
T19483 15792-15793 . denotes .
T19484 15794-15800 NNS denotes Values
T19485 15801-15804 VBP denotes are
T19486 15805-15808 DT denotes the
T19487 15809-15813 JJ denotes mean
T19488 15814-15815 NN denotes ±
T19489 15816-15820 NNP denotes S.D.
T19490 15821-15823 IN denotes of
T19491 15824-15828 CD denotes four
T19492 15829-15841 JJ denotes experimental
T19493 15842-15849 NNS denotes animals
T19494 15849-15850 . denotes .
T19495 15851-15852 SYM denotes *
T19496 15853-15862 VBZ denotes indicates
T19497 15863-15876 RB denotes statistically
T19498 15877-15888 JJ denotes significant
T19499 15889-15900 NNS denotes differences
T19500 15901-15905 IN denotes from
T19501 15906-15910 CD denotes CCR5
T19502 15910-15911 CD denotes +
T19503 15911-15912 NN denotes /
T19504 15912-15913 NN denotes +
T19505 15914-15918 NNS denotes mice
T19506 15918-15919 . denotes .
T19507 15920-15925 NNP denotes Scale
T19508 15926-15929 NN denotes bar
T19509 15930-15939 VBZ denotes indicates
T19510 15940-15942 CD denotes 50
T19511 15943-15945 NN denotes µm
T19512 15945-15946 . denotes .
T19513 15947-15948 NN denotes F
T19514 15949-15952 CC denotes and
T19515 15953-15954 NNP denotes G
T19516 15954-15955 , denotes ,
T19517 15956-15966 NNP denotes Expression
T19518 15967-15969 IN denotes of
T19519 15970-15976 NNP denotes IL-1Ra
T19520 15977-15980 VBD denotes was
T19521 15981-15989 VBN denotes analyzed
T19522 15990-15992 IN denotes by
T19523 15993-16000 JJ denotes western
T19524 16001-16009 VBG denotes blotting
T19525 16010-16012 IN denotes in
T19526 16013-16018 NN denotes tumor
T19527 16019-16022 CC denotes and
T19528 16023-16029 NN denotes spleen
T19529 16030-16037 NNS denotes tissues
T19530 16037-16038 . denotes .
T19531 16039-16043 DT denotes Each
T19532 16044-16048 NN denotes band
T19533 16049-16051 VBZ denotes is
T19534 16052-16066 NN denotes representative
T19535 16067-16069 IN denotes of
T19536 16070-16075 CD denotes three
T19537 16076-16087 JJ denotes independent
T19538 16088-16100 JJ denotes experimental
T19539 16101-16108 NNS denotes results
T19540 16108-16109 . denotes .
T19541 16110-16114 NNS denotes Data
T19542 16115-16118 VBP denotes are
T19543 16119-16124 VBZ denotes means
T19544 16125-16126 NNP denotes ±
T19545 16127-16131 NNP denotes S.D.
T19546 16132-16134 IN denotes of
T19547 16135-16140 CD denotes three
T19548 16141-16153 JJ denotes experimental
T19549 16154-16161 NNS denotes animals
T19550 16161-16162 . denotes .
T19551 16163-16164 SYM denotes *
T19552 16165-16174 VBZ denotes indicates
T19553 16175-16186 JJ denotes significant
T19554 16187-16197 NN denotes difference
T19555 16198-16202 IN denotes from
T19556 16203-16207 CD denotes CCR5
T19557 16207-16208 CD denotes +
T19558 16208-16209 NN denotes /
T19559 16209-16210 NN denotes +
T19560 16211-16215 NNS denotes mice
T19561 16216-16217 -LRB- denotes (
T19562 16217-16218 JJ denotes p
T19563 16218-16219 NN denotes <
T19564 16219-16223 CD denotes 0.05
T19565 16223-16224 -RRB- denotes )
T19566 16224-16225 . denotes .
T8102 16227-16236 NNP denotes Induction
T8103 16237-16239 IN denotes of
T8104 16240-16243 NNP denotes CD8
T8105 16244-16245 NNP denotes T
T8106 16246-16251 NNS denotes cells
T8107 16252-16255 CC denotes and
T8108 16256-16258 NNP denotes NK
T8109 16259-16263 NNP denotes Cell
T8110 16264-16276 NNP denotes Infiltration
T8111 16277-16281 IN denotes into
T8112 16282-16287 NNP denotes Tumor
T8113 16288-16291 CC denotes and
T8114 16292-16298 NNP denotes Spleen
T8115 16299-16301 IN denotes of
T8116 16302-16306 NNP denotes CCR5
T8117 16306-16307 NNP denotes −
T8118 16307-16308 VBD denotes /
T8119 16308-16309 CD denotes −
T8120 16310-16314 NNP denotes Mice
T8121 16315-16317 TO denotes To
T8122 16318-16329 VB denotes investigate
T8123 16330-16337 IN denotes whether
T8124 16338-16341 DT denotes the
T8125 16342-16352 NN denotes inhibition
T8126 16353-16355 IN denotes of
T8127 16356-16361 NN denotes tumor
T8128 16362-16368 NN denotes growth
T8129 16369-16371 IN denotes in
T8130 16372-16376 CD denotes CCR5
T8131 16376-16377 CD denotes −
T8132 16377-16378 NN denotes /
T8133 16378-16379 NN denotes −
T8134 16380-16384 NNS denotes mice
T8135 16385-16387 VBZ denotes is
T8136 16388-16395 VBN denotes related
T8137 16396-16398 TO denotes to
T8138 16399-16413 JJ denotes tumor-specific
T8139 16414-16420 JJ denotes immune
T8140 16421-16430 NNS denotes responses
T8141 16430-16431 , denotes ,
T8142 16432-16434 PRP denotes we
T8143 16435-16443 VBD denotes analyzed
T8144 16444-16447 DT denotes the
T8145 16448-16460 NN denotes distribution
T8146 16461-16469 NNS denotes patterns
T8147 16470-16472 IN denotes of
T8148 16473-16476 CD denotes CD8
T8149 16476-16477 CD denotes +
T8150 16478-16487 JJ denotes cytotoxic
T8151 16488-16489 NNP denotes T
T8152 16490-16494 NN denotes cell
T8153 16495-16498 CC denotes and
T8154 16499-16503 NNP denotes CD57
T8155 16503-16504 NNP denotes +
T8156 16505-16512 NNP denotes Natural
T8157 16513-16519 NNP denotes Killer
T8158 16520-16525 NNS denotes cells
T8159 16526-16528 IN denotes in
T8160 16529-16534 NN denotes tumor
T8161 16535-16538 CC denotes and
T8162 16539-16545 NN denotes spleen
T8163 16546-16553 NNS denotes tissues
T8164 16553-16554 . denotes .
T8165 16555-16557 IN denotes By
T8166 16558-16566 VBG denotes staining
T8167 16567-16570 DT denotes the
T8168 16571-16576 NN denotes tumor
T8169 16577-16585 NNS denotes sections
T8170 16586-16590 IN denotes from
T8171 16591-16595 CD denotes CCR5
T8172 16595-16596 CD denotes −
T8173 16596-16597 NN denotes /
T8174 16597-16598 NN denotes −
T8175 16599-16603 NNS denotes mice
T8176 16603-16604 , denotes ,
T8177 16605-16607 PRP denotes we
T8178 16608-16613 VBD denotes found
T8179 16614-16618 IN denotes that
T8180 16619-16624 EX denotes there
T8181 16625-16628 VBD denotes was
T8182 16629-16630 DT denotes a
T8183 16631-16642 JJ denotes significant
T8184 16643-16649 NN denotes influx
T8185 16650-16652 IN denotes of
T8186 16653-16656 CD denotes CD8
T8187 16656-16657 CD denotes +
T8188 16658-16663 NNS denotes cells
T8189 16664-16668 IN denotes into
T8190 16669-16672 DT denotes the
T8191 16673-16678 NN denotes tumor
T8192 16678-16679 , denotes ,
T8193 16680-16682 RB denotes as
T8194 16683-16687 RB denotes well
T8195 16688-16690 IN denotes as
T8196 16691-16693 DT denotes an
T8197 16694-16702 NN denotes increase
T8198 16703-16705 IN denotes in
T8199 16706-16709 DT denotes the
T8200 16710-16716 NN denotes number
T8201 16717-16719 IN denotes of
T8202 16720-16732 VBG denotes infiltrating
T8203 16733-16735 NNP denotes NK
T8204 16736-16741 NNS denotes cells
T8205 16742-16743 -LRB- denotes (
T8206 16743-16749 NN denotes Figure
T8207 16750-16752 NN denotes 5A
T8208 16752-16753 -RRB- denotes )
T8209 16753-16754 . denotes .
T8210 16755-16758 CD denotes CD8
T8211 16758-16759 CD denotes +
T8212 16760-16761 NNP denotes T
T8213 16762-16767 NNS denotes cells
T8214 16768-16771 CC denotes and
T8215 16772-16776 NNP denotes CD57
T8216 16776-16777 NNP denotes +
T8217 16778-16780 NNP denotes NK
T8218 16781-16786 NNS denotes cells
T8219 16787-16791 VBD denotes were
T8220 16792-16798 VBN denotes spread
T8221 16799-16808 RB denotes diffusely
T8222 16809-16819 IN denotes throughout
T8223 16820-16823 DT denotes the
T8224 16824-16830 JJ denotes entire
T8225 16831-16839 NNS denotes sections
T8226 16839-16840 . denotes .
T8227 16841-16843 TO denotes To
T8228 16844-16851 RBR denotes further
T8229 16852-16863 VB denotes investigate
T8230 16864-16867 DT denotes the
T8231 16868-16879 NNS denotes differences
T8232 16880-16882 IN denotes in
T8233 16883-16886 DT denotes the
T8234 16887-16894 NNS denotes numbers
T8235 16895-16897 IN denotes of
T8236 16898-16901 CD denotes CD8
T8237 16901-16902 CD denotes +
T8238 16903-16904 NNP denotes T
T8239 16905-16910 NNS denotes cells
T8240 16911-16914 CC denotes and
T8241 16915-16919 NNP denotes CD57
T8242 16919-16920 NNP denotes +
T8243 16921-16923 NNP denotes NK
T8244 16924-16929 NNS denotes cells
T8245 16930-16937 IN denotes between
T8246 16938-16942 CD denotes CCR5
T8247 16942-16943 CD denotes +
T8248 16943-16944 NN denotes /
T8249 16944-16945 NN denotes +
T8250 16946-16950 NNS denotes mice
T8251 16951-16954 CC denotes and
T8252 16955-16959 NNS denotes CCR5
T8253 16959-16960 VBP denotes −
T8254 16960-16961 CD denotes /
T8255 16961-16962 CD denotes −
T8256 16963-16967 NNS denotes mice
T8257 16968-16970 IN denotes in
T8258 16971-16987 JJ denotes immunity-related
T8259 16988-16993 NN denotes organ
T8260 16993-16994 , denotes ,
T8261 16995-16997 PRP denotes we
T8262 16998-17002 RB denotes also
T8263 17003-17011 VBD denotes analyzed
T8264 17012-17015 DT denotes the
T8265 17016-17019 NNP denotes CD8
T8266 17020-17023 CC denotes and
T8267 17024-17028 NNP denotes CD57
T8268 17029-17037 JJ denotes reactive
T8269 17038-17042 NN denotes cell
T8270 17043-17049 NN denotes number
T8271 17050-17052 IN denotes in
T8272 17053-17059 JJ denotes spleen
T8273 17060-17067 NNS denotes tissues
T8274 17067-17068 . denotes .
T8275 17069-17072 DT denotes The
T8276 17073-17079 NN denotes number
T8277 17080-17082 IN denotes of
T8278 17083-17086 CD denotes CD8
T8279 17086-17087 CD denotes +
T8280 17088-17089 NNP denotes T
T8281 17090-17095 NNS denotes cells
T8282 17096-17099 CC denotes and
T8283 17100-17104 NNP denotes CD57
T8284 17104-17105 NNP denotes +
T8285 17106-17108 NNP denotes NK
T8286 17109-17114 NNS denotes cells
T8287 17115-17119 VBD denotes were
T8288 17120-17126 JJR denotes higher
T8289 17127-17129 IN denotes in
T8290 17130-17133 DT denotes the
T8291 17134-17140 NN denotes spleen
T8292 17141-17143 IN denotes of
T8293 17144-17147 DT denotes the
T8294 17148-17152 NNP denotes CCR5
T8295 17152-17153 NNP denotes −
T8296 17153-17154 VBD denotes /
T8297 17154-17155 CD denotes −
T8298 17156-17160 NNS denotes mice
T8299 17161-17165 IN denotes than
T8300 17166-17168 IN denotes in
T8301 17169-17172 DT denotes the
T8302 17173-17179 NN denotes spleen
T8303 17180-17182 IN denotes of
T8304 17183-17186 DT denotes the
T8305 17187-17191 NNP denotes CCR5
T8306 17191-17192 NNP denotes +
T8307 17192-17193 VBD denotes /
T8308 17193-17194 CD denotes +
T8309 17195-17199 NNS denotes mice
T8310 17200-17201 -LRB- denotes (
T8311 17201-17207 NN denotes Figure
T8312 17208-17210 NN denotes 5B
T8313 17210-17211 -RRB- denotes )
T8314 17211-17212 . denotes .
T8315 17213-17218 DT denotes These
T8316 17219-17223 NNS denotes data
T8317 17224-17231 VBP denotes suggest
T8318 17232-17236 IN denotes that
T8319 17237-17239 IN denotes by
T8320 17240-17249 VBG denotes promoting
T8321 17250-17253 DT denotes the
T8322 17254-17266 NN denotes infiltration
T8323 17267-17269 IN denotes of
T8324 17270-17273 CD denotes CD8
T8325 17274-17275 NNP denotes T
T8326 17276-17281 NNS denotes cells
T8327 17282-17285 CC denotes and
T8328 17286-17288 NNP denotes NK
T8329 17289-17294 NNS denotes cells
T8330 17294-17295 , denotes ,
T8331 17296-17301 WDT denotes which
T8332 17302-17305 VBP denotes are
T8333 17306-17312 JJ denotes potent
T8334 17313-17322 JJ denotes cytotoxic
T8335 17323-17332 NNS denotes effectors
T8336 17333-17336 IN denotes for
T8337 17337-17343 NNS denotes tumors
T8338 17343-17344 , denotes ,
T8339 17345-17350 MD denotes could
T8340 17351-17355 VB denotes play
T8341 17356-17357 DT denotes a
T8342 17358-17362 NN denotes role
T8343 17363-17365 IN denotes in
T8344 17366-17368 DT denotes an
T8345 17369-17379 JJ denotes anti-tumor
T8346 17380-17386 NN denotes effect
T8347 17387-17389 IN denotes in
T8348 17390-17394 CD denotes CCR5
T8349 17394-17395 CD denotes −
T8350 17395-17396 NN denotes /
T8351 17396-17397 NN denotes −
T8352 17398-17402 NNS denotes mice
T8353 17402-17403 . denotes .
T19754 17448-17457 NNP denotes Induction
T19755 17458-17460 IN denotes of
T19756 17461-17464 DT denotes the
T19757 17465-17477 NN denotes infiltration
T19758 17478-17480 IN denotes of
T19759 17481-17484 CD denotes CD8
T19760 17484-17485 CD denotes +
T19761 17486-17487 NNP denotes T
T19762 17488-17493 NNS denotes cells
T19763 17494-17497 CC denotes and
T19764 17498-17500 NNP denotes NK
T19765 17501-17506 NNS denotes cells
T19766 17507-17511 IN denotes into
T19767 17512-17517 NN denotes tumor
T19768 17517-17518 , denotes ,
T19769 17519-17522 CC denotes and
T19770 17523-17531 NN denotes increase
T19771 17532-17534 IN denotes in
T19772 17535-17541 NN denotes spleen
T19773 17542-17544 IN denotes of
T19774 17545-17549 CD denotes CCR5
T19775 17549-17550 CD denotes −
T19776 17550-17551 NN denotes /
T19777 17551-17552 NN denotes −
T19778 17553-17557 NNS denotes mice
T19779 17557-17558 . denotes .
T19780 17559-17560 DT denotes A
T19781 17561-17564 CC denotes and
T19782 17565-17566 NNP denotes B
T19783 17566-17567 , denotes ,
T19784 17568-17587 NNP denotes Immunolfluorescence
T19785 17588-17596 NN denotes analysis
T19786 17597-17600 VBD denotes was
T19787 17601-17605 VBN denotes used
T19788 17606-17608 TO denotes to
T19789 17609-17618 VB denotes determine
T19790 17619-17622 DT denotes the
T19791 17623-17633 NN denotes expression
T19792 17634-17640 NNS denotes levels
T19793 17641-17643 IN denotes of
T19794 17644-17647 NNP denotes CD8
T19795 17648-17649 -LRB- denotes (
T19796 17649-17652 NNP denotes CD8
T19797 17652-17653 NNP denotes +
T19798 17654-17663 JJ denotes cytotoxic
T19799 17664-17670 NNP denotes T-cell
T19800 17671-17678 NN denotes surface
T19801 17679-17685 NN denotes marker
T19802 17685-17686 -RRB- denotes )
T19803 17687-17690 CC denotes and
T19804 17691-17695 NNP denotes CD57
T19805 17696-17697 -LRB- denotes (
T19806 17697-17699 NNP denotes NK
T19807 17700-17704 NN denotes cell
T19808 17705-17711 NN denotes marker
T19809 17711-17712 -RRB- denotes )
T19810 17713-17715 IN denotes in
T19811 17716-17721 NN denotes tumor
T19812 17722-17725 CC denotes and
T19813 17726-17732 JJ denotes spleen
T19814 17733-17741 NNS denotes sections
T19815 17741-17742 . denotes .
T19816 17743-17746 DT denotes The
T19817 17747-17753 NNS denotes images
T19818 17754-17759 VBN denotes shown
T19819 17760-17763 VBP denotes are
T19820 17764-17778 NN denotes representative
T19821 17779-17781 IN denotes of
T19822 17782-17787 CD denotes three
T19823 17788-17796 JJ denotes separate
T19824 17797-17808 NNS denotes experiments
T19825 17809-17818 VBN denotes performed
T19826 17819-17821 IN denotes in
T19827 17822-17832 NN denotes triplicate
T19828 17832-17833 . denotes .
T19829 17834-17839 NNP denotes Scale
T19830 17840-17844 NNS denotes bars
T19831 17845-17853 VBP denotes indicate
T19832 17854-17856 CD denotes 50
T19833 17857-17859 NN denotes µm
T19834 17860-17861 -LRB- denotes (
T19835 17861-17862 NNP denotes A
T19836 17862-17863 -RRB- denotes )
T19837 17864-17867 CC denotes and
T19838 17868-17871 CD denotes 100
T19839 17872-17874 NN denotes µm
T19840 17875-17876 -LRB- denotes (
T19841 17876-17877 NNP denotes B
T19842 17877-17878 -RRB- denotes )
T19843 17878-17879 . denotes .
T19844 17880-17881 NNP denotes C
T19845 17882-17885 CC denotes and
T19846 17886-17887 NNP denotes D
T19847 17887-17888 , denotes ,
T19848 17889-17897 NNP denotes Analysis
T19849 17898-17900 IN denotes of
T19850 17901-17911 NN denotes lymphocyte
T19851 17912-17922 NNS denotes phenotypes
T19852 17922-17923 . denotes .
T19853 17924-17927 DT denotes The
T19854 17928-17933 NN denotes tumor
T19855 17934-17937 CC denotes and
T19856 17938-17944 NN denotes spleen
T19857 17945-17952 NNS denotes tissues
T19858 17953-17957 VBD denotes were
T19859 17958-17967 VBN denotes separated
T19860 17968-17970 IN denotes at
T19861 17971-17976 NN denotes study
T19862 17977-17988 NN denotes termination
T19863 17989-17990 -LRB- denotes (
T19864 17990-17993 NNP denotes Day
T19865 17994-17996 CD denotes 31
T19866 17996-17997 -RRB- denotes )
T19867 17997-17998 . denotes .
T19868 17999-18003 NN denotes Flow
T19869 18004-18013 NN denotes cytometry
T19870 18014-18022 NN denotes analysis
T19871 18023-18026 VBD denotes was
T19872 18027-18036 VBN denotes performed
T19873 18037-18042 VBG denotes using
T19874 18043-18051 NNP denotes FACSAria
T19875 18052-18056 NN denotes flow
T19876 18057-18066 NN denotes cytometry
T19877 18066-18067 , denotes ,
T19878 18068-18071 CC denotes and
T19879 18072-18081 VBP denotes represent
T19880 18082-18086 NNS denotes data
T19881 18087-18091 VBD denotes were
T19882 18092-18097 VBN denotes shown
T19883 18097-18098 . denotes .
T19884 18099-18103 NNS denotes Data
T19885 18104-18107 VBP denotes are
T19886 18108-18113 VBZ denotes means
T19887 18114-18115 NNP denotes ±
T19888 18116-18120 NNP denotes S.D.
T19889 18121-18123 IN denotes of
T19890 18124-18128 CD denotes four
T19891 18129-18141 JJ denotes experimental
T19892 18142-18149 NNS denotes animals
T19893 18149-18150 . denotes .
T8354 18151-18153 TO denotes To
T8355 18154-18161 VB denotes analyze
T8356 18162-18165 DT denotes the
T8357 18166-18170 NN denotes cell
T8358 18171-18180 NN denotes phenotype
T8359 18181-18187 NN denotes change
T8360 18188-18190 IN denotes in
T8361 18191-18195 CD denotes CCR5
T8362 18195-18196 CD denotes −
T8363 18196-18197 NN denotes /
T8364 18197-18198 NN denotes −
T8365 18199-18203 NNS denotes mice
T8366 18204-18207 CC denotes and
T8367 18208-18212 NNS denotes CCR5
T8368 18212-18213 VBP denotes +
T8369 18213-18214 CD denotes /
T8370 18214-18215 CD denotes +
T8371 18216-18220 NNS denotes mice
T8372 18221-18223 IN denotes by
T8373 18224-18235 NN denotes inoculation
T8374 18236-18238 IN denotes of
T8375 18239-18242 DT denotes the
T8376 18243-18251 NN denotes melanoma
T8377 18252-18256 NN denotes cell
T8378 18256-18257 , denotes ,
T8379 18258-18269 NNS denotes lymphocytes
T8380 18270-18274 VBD denotes were
T8381 18275-18283 VBN denotes isolated
T8382 18284-18288 IN denotes from
T8383 18289-18292 DT denotes the
T8384 18293-18298 NN denotes tumor
T8385 18299-18302 CC denotes and
T8386 18303-18309 NN denotes spleen
T8387 18310-18317 NNS denotes tissues
T8388 18317-18318 . denotes .
T8389 18319-18322 DT denotes The
T8390 18323-18324 NNP denotes B
T8391 18324-18325 , denotes ,
T8392 18326-18329 NNP denotes CD3
T8393 18330-18331 NNP denotes T
T8394 18331-18332 , denotes ,
T8395 18333-18336 NNP denotes CD4
T8396 18337-18338 NNP denotes T
T8397 18338-18339 , denotes ,
T8398 18340-18342 NNP denotes CD
T8399 18343-18344 CD denotes 8
T8400 18345-18346 NNP denotes T
T8401 18347-18350 CC denotes and
T8402 18351-18353 NNP denotes NK
T8403 18354-18358 NN denotes cell
T8404 18359-18366 NN denotes portion
T8405 18367-18369 IN denotes of
T8406 18370-18374 CD denotes CCR5
T8407 18374-18375 CD denotes −
T8408 18375-18376 NN denotes /
T8409 18376-18377 NN denotes −
T8410 18378-18382 NNS denotes mice
T8411 18383-18388 NN denotes tumor
T8412 18389-18395 NN denotes tissue
T8413 18396-18400 VBD denotes were
T8414 18401-18404 CD denotes 7.2
T8415 18404-18405 NN denotes %
T8416 18405-18406 , denotes ,
T8417 18407-18411 CD denotes 48.2
T8418 18411-18412 NN denotes %
T8419 18412-18413 , denotes ,
T8420 18414-18418 CD denotes 16.9
T8421 18418-18419 NN denotes %
T8422 18419-18420 , denotes ,
T8423 18421-18425 CD denotes 32.1
T8424 18425-18426 NN denotes %
T8425 18427-18430 CC denotes and
T8426 18431-18434 CD denotes 7.8
T8427 18434-18435 NN denotes %
T8428 18435-18436 , denotes ,
T8429 18437-18449 RB denotes respectively
T8430 18449-18450 , denotes ,
T8431 18451-18459 VBN denotes compared
T8432 18460-18462 TO denotes to
T8433 18463-18466 CD denotes 2.9
T8434 18466-18467 NN denotes %
T8435 18467-18468 , denotes ,
T8436 18469-18473 CD denotes 11.1
T8437 18473-18474 NN denotes %
T8438 18474-18475 , denotes ,
T8439 18476-18479 CD denotes 2.3
T8440 18479-18480 NN denotes %
T8441 18480-18481 , denotes ,
T8442 18482-18485 CD denotes 0.6
T8443 18485-18486 NN denotes %
T8444 18487-18490 CC denotes and
T8445 18491-18494 CD denotes 3.1
T8446 18494-18495 NN denotes %
T8447 18496-18498 IN denotes of
T8448 18499-18503 CD denotes CCR5
T8449 18503-18504 CD denotes +
T8450 18504-18505 NN denotes /
T8451 18505-18506 NN denotes +
T8452 18507-18511 NNS denotes mice
T8453 18512-18513 -LRB- denotes (
T8454 18513-18519 NN denotes Figure
T8455 18520-18522 NN denotes 5C
T8456 18522-18523 -RRB- denotes )
T8457 18523-18524 . denotes .
T8458 18525-18528 DT denotes The
T8459 18529-18540 NNS denotes lymphocytes
T8460 18541-18545 WDT denotes that
T8461 18546-18557 VBD denotes infiltrated
T8462 18558-18561 DT denotes the
T8463 18562-18567 NN denotes tumor
T8464 18568-18574 NN denotes tissue
T8465 18575-18577 IN denotes of
T8466 18578-18581 DT denotes the
T8467 18582-18586 NNP denotes CCR5
T8468 18586-18587 NNP denotes −
T8469 18587-18588 VBD denotes /
T8470 18588-18589 CD denotes −
T8471 18590-18594 NNS denotes mice
T8472 18595-18599 RB denotes also
T8473 18600-18603 VBD denotes had
T8474 18604-18610 JJR denotes higher
T8475 18611-18617 NNS denotes levels
T8476 18618-18620 IN denotes of
T8477 18621-18625 NNP denotes CD19
T8478 18625-18626 , denotes ,
T8479 18627-18630 NNP denotes CD3
T8480 18630-18631 , denotes ,
T8481 18632-18635 NNP denotes CD4
T8482 18635-18636 , denotes ,
T8483 18637-18640 NNP denotes CD8
T8484 18641-18644 CC denotes and
T8485 18645-18649 NNP denotes CD57
T8486 18650-18654 WRB denotes when
T8487 18655-18663 VBN denotes compared
T8488 18664-18666 TO denotes to
T8489 18667-18670 DT denotes the
T8490 18671-18675 NNP denotes CCR5
T8491 18675-18676 NNP denotes +
T8492 18676-18677 VBD denotes /
T8493 18677-18678 CD denotes +
T8494 18679-18683 NNS denotes mice
T8495 18683-18684 . denotes .
T8496 18685-18688 DT denotes The
T8497 18689-18690 NNP denotes B
T8498 18690-18691 , denotes ,
T8499 18692-18695 NNP denotes CD3
T8500 18696-18697 NNP denotes T
T8501 18697-18698 , denotes ,
T8502 18699-18702 NNP denotes CD4
T8503 18703-18704 NNP denotes T
T8504 18704-18705 , denotes ,
T8505 18706-18708 NNP denotes CD
T8506 18709-18710 CD denotes 8
T8507 18711-18712 NNP denotes T
T8508 18713-18716 CC denotes and
T8509 18717-18719 NNP denotes NK
T8510 18720-18724 NN denotes cell
T8511 18725-18732 NN denotes portion
T8512 18733-18735 IN denotes of
T8513 18736-18739 DT denotes the
T8514 18740-18744 NNP denotes CCR5
T8515 18744-18745 CD denotes −
T8516 18745-18746 CD denotes /
T8517 18746-18747 NN denotes −
T8518 18748-18752 NNS denotes mice
T8519 18753-18759 VBP denotes spleen
T8520 18760-18764 VBD denotes were
T8521 18765-18769 CD denotes 61.3
T8522 18769-18770 NN denotes %
T8523 18770-18771 , denotes ,
T8524 18772-18776 CD denotes 33.4
T8525 18776-18777 NN denotes %
T8526 18777-18778 , denotes ,
T8527 18779-18783 CD denotes 17.6
T8528 18783-18784 NN denotes %
T8529 18784-18785 , denotes ,
T8530 18786-18789 CD denotes 9.2
T8531 18789-18790 NN denotes %
T8532 18791-18794 CC denotes and
T8533 18795-18798 CD denotes 0.6
T8534 18798-18799 NN denotes %
T8535 18799-18800 , denotes ,
T8536 18801-18813 RB denotes respectively
T8537 18814-18822 VBN denotes compared
T8538 18823-18825 TO denotes to
T8539 18826-18830 CD denotes 38.3
T8540 18830-18831 NN denotes %
T8541 18831-18832 , denotes ,
T8542 18833-18836 CD denotes 5.9
T8543 18836-18837 NN denotes %
T8544 18837-18838 , denotes ,
T8545 18839-18842 CD denotes 4.0
T8546 18842-18843 NN denotes %
T8547 18843-18844 , denotes ,
T8548 18845-18848 CD denotes 1.0
T8549 18848-18849 NN denotes %
T8550 18850-18853 CC denotes and
T8551 18854-18857 CD denotes 3.9
T8552 18857-18858 NN denotes %
T8553 18859-18861 IN denotes of
T8554 18862-18865 DT denotes the
T8555 18866-18870 NNP denotes CCR5
T8556 18870-18871 NNP denotes +
T8557 18871-18872 VBD denotes /
T8558 18872-18873 CD denotes +
T8559 18874-18878 NNS denotes mice
T8560 18879-18880 -LRB- denotes (
T8561 18880-18886 NN denotes Figure
T8562 18887-18889 CD denotes 5D
T8563 18889-18890 -RRB- denotes )
T8564 18890-18891 . denotes .
T8565 18892-18897 DT denotes These
T8566 18898-18902 NNS denotes data
T8567 18903-18910 VBP denotes suggest
T8568 18911-18915 IN denotes that
T8569 18916-18918 IN denotes by
T8570 18919-18928 VBG denotes promoting
T8571 18929-18932 DT denotes the
T8572 18933-18945 NN denotes infiltration
T8573 18946-18948 IN denotes of
T8574 18949-18952 CD denotes CD8
T8575 18953-18954 NNP denotes T
T8576 18955-18960 NNS denotes cells
T8577 18961-18964 CC denotes and
T8578 18965-18967 NNP denotes NK
T8579 18968-18973 NNS denotes cells
T8580 18973-18974 , denotes ,
T8581 18975-18980 WDT denotes which
T8582 18981-18984 VBP denotes are
T8583 18985-18991 JJ denotes potent
T8584 18992-19001 JJ denotes cytotoxic
T8585 19002-19011 NNS denotes effectors
T8586 19012-19015 IN denotes for
T8587 19016-19022 NNS denotes tumors
T8588 19022-19023 , denotes ,
T8589 19024-19029 MD denotes could
T8590 19030-19034 VB denotes play
T8591 19035-19036 DT denotes a
T8592 19037-19041 NN denotes role
T8593 19042-19044 IN denotes in
T8594 19045-19048 DT denotes the
T8595 19049-19059 NN denotes inhibition
T8596 19060-19062 IN denotes of
T8597 19063-19068 NN denotes tumor
T8598 19069-19075 NN denotes growth
T8599 19076-19078 IN denotes in
T8600 19079-19083 CD denotes CCR5
T8601 19083-19084 CD denotes −
T8602 19084-19085 NN denotes /
T8603 19085-19086 NN denotes −
T8604 19087-19091 NNS denotes mice
T8605 19091-19092 . denotes .
T11696 19105-19107 IN denotes In
T11697 19108-19111 DT denotes the
T11698 19112-19119 JJ denotes present
T11699 19120-19125 NN denotes study
T11700 19125-19126 , denotes ,
T11701 19127-19129 PRP denotes we
T11702 19130-19135 VBD denotes found
T11703 19136-19140 IN denotes that
T11704 19141-19146 NN denotes tumor
T11705 19147-19153 NN denotes weight
T11706 19154-19157 CC denotes and
T11707 19158-19164 NN denotes volume
T11708 19165-19169 VBD denotes were
T11709 19170-19174 RB denotes much
T11710 19175-19182 JJR denotes smaller
T11711 19183-19185 IN denotes in
T11712 19186-19189 DT denotes the
T11713 19190-19194 NNP denotes CCR5
T11714 19194-19195 NNP denotes −
T11715 19195-19196 VBD denotes /
T11716 19196-19197 CD denotes −
T11717 19198-19202 NNS denotes mice
T11718 19203-19211 VBN denotes compared
T11719 19212-19214 TO denotes to
T11720 19215-19218 DT denotes the
T11721 19219-19223 NNP denotes CCR5
T11722 19223-19224 NNP denotes +
T11723 19224-19225 VBD denotes /
T11724 19225-19226 CD denotes +
T11725 19227-19231 NNS denotes mice
T11726 19232-19242 VBN denotes inoculated
T11727 19243-19247 IN denotes with
T11728 19248-19251 NNP denotes B16
T11729 19252-19260 NN denotes melanoma
T11730 19261-19266 NNS denotes cells
T11731 19267-19268 -LRB- denotes (
T11732 19268-19274 NN denotes Figure
T11733 19275-19277 CD denotes 1A
T11734 19278-19281 CC denotes and
T11735 19282-19284 CD denotes 1B
T11736 19284-19285 -RRB- denotes )
T11737 19285-19286 . denotes .
T11738 19287-19290 DT denotes The
T11739 19291-19296 NN denotes tumor
T11740 19297-19303 NN denotes growth
T11741 19304-19314 NN denotes inhibition
T11742 19315-19317 IN denotes in
T11743 19318-19321 DT denotes the
T11744 19322-19326 NNP denotes CCR5
T11745 19326-19327 NNP denotes −
T11746 19327-19328 VBD denotes /
T11747 19328-19329 CD denotes −
T11748 19330-19334 NNS denotes mice
T11749 19335-19338 VBD denotes was
T11750 19339-19349 VBN denotes associated
T11751 19350-19354 IN denotes with
T11752 19355-19358 DT denotes the
T11753 19359-19369 NN denotes inhibition
T11754 19370-19372 IN denotes of
T11755 19373-19387 RB denotes constitutively
T11756 19388-19397 VBN denotes activated
T11757 19398-19403 NNP denotes NF-κB
T11758 19404-19407 CC denotes and
T11759 19408-19417 NN denotes elevation
T11760 19418-19420 IN denotes of
T11761 19421-19427 NN denotes IL-1Ra
T11762 19428-19430 IN denotes in
T11763 19431-19434 DT denotes the
T11764 19435-19440 NN denotes tumor
T11765 19441-19447 NN denotes tissue
T11766 19447-19448 . denotes .
T11767 19449-19453 DT denotes This
T11768 19454-19464 JJ denotes anti-tumor
T11769 19465-19473 NN denotes activity
T11770 19474-19477 VBD denotes was
T11771 19478-19482 RB denotes also
T11772 19483-19493 VBN denotes associated
T11773 19494-19498 IN denotes with
T11774 19499-19508 VBN denotes decreased
T11775 19509-19519 NN denotes expression
T11776 19520-19522 IN denotes of
T11777 19523-19528 JJ denotes NF-κB
T11778 19529-19535 NN denotes target
T11779 19536-19550 JJ denotes anti-apoptotic
T11780 19550-19551 , denotes ,
T11781 19552-19556 NN denotes cell
T11782 19557-19570 NN denotes proliferative
T11783 19570-19571 , denotes ,
T11784 19572-19575 CC denotes and
T11785 19576-19581 NN denotes tumor
T11786 19582-19591 VBG denotes promoting
T11787 19592-19597 NNS denotes genes
T11788 19598-19599 -LRB- denotes (
T11789 19599-19604 NN denotes Bcl-2
T11790 19605-19608 CC denotes and
T11791 19609-19615 NN denotes C-IAP1
T11792 19615-19616 -RRB- denotes )
T11793 19617-19620 CC denotes but
T11794 19621-19625 IN denotes with
T11795 19626-19635 VBN denotes increased
T11796 19636-19646 NN denotes expression
T11797 19647-19649 IN denotes of
T11798 19650-19655 PRP$ denotes their
T11799 19656-19662 NN denotes target
T11800 19663-19672 JJ denotes apoptotic
T11801 19673-19678 NNS denotes genes
T11802 19678-19679 : denotes ;
T11803 19680-19687 VBN denotes cleaved
T11804 19688-19697 JJ denotes caspase-3
T11805 19698-19701 CC denotes and
T11806 19702-19703 CD denotes 9
T11807 19703-19704 , denotes ,
T11808 19705-19708 CC denotes and
T11809 19709-19712 NNP denotes Bax
T11810 19713-19714 -LRB- denotes (
T11811 19714-19720 NNP denotes Figure
T11812 19721-19725 NNP denotes 3A-D
T11813 19725-19726 -RRB- denotes )
T11814 19726-19727 . denotes .
T11815 19728-19730 IN denotes In
T11816 19731-19734 DT denotes the
T11817 19735-19740 NN denotes tumor
T11818 19741-19744 CC denotes and
T11819 19745-19748 DT denotes the
T11820 19749-19755 NN denotes spleen
T11821 19755-19756 , denotes ,
T11822 19757-19760 DT denotes the
T11823 19761-19767 NN denotes number
T11824 19768-19770 IN denotes of
T11825 19771-19780 JJ denotes cytotoxic
T11826 19781-19784 NNP denotes CD8
T11827 19784-19785 CD denotes +
T11828 19786-19787 NNP denotes T
T11829 19788-19793 NNS denotes cells
T11830 19793-19794 , denotes ,
T11831 19795-19799 NNP denotes CD57
T11832 19799-19800 NNP denotes +
T11833 19801-19808 JJ denotes natural
T11834 19809-19815 NN denotes killer
T11835 19816-19821 NNS denotes cells
T11836 19821-19822 , denotes ,
T11837 19823-19826 CC denotes and
T11838 19827-19830 DT denotes the
T11839 19831-19837 NNS denotes levels
T11840 19838-19840 IN denotes of
T11841 19841-19847 NN denotes IL-1Ra
T11842 19848-19852 VBD denotes were
T11843 19853-19862 VBN denotes increased
T11844 19863-19864 -LRB- denotes (
T11845 19864-19870 NN denotes Figure
T11846 19871-19872 CD denotes 4
T11847 19873-19876 CC denotes and
T11848 19877-19878 CD denotes 5
T11849 19878-19879 -RRB- denotes )
T11850 19879-19880 . denotes .
T11851 19881-19886 DT denotes These
T11852 19887-19895 NNS denotes findings
T11853 19896-19903 VBP denotes suggest
T11854 19904-19908 IN denotes that
T11855 19909-19917 NN denotes melanoma
T11856 19918-19924 NN denotes growth
T11857 19925-19928 VBD denotes was
T11858 19929-19938 VBN denotes inhibited
T11859 19939-19941 IN denotes in
T11860 19942-19945 DT denotes the
T11861 19946-19950 NNP denotes CCR5
T11862 19950-19951 NNP denotes −
T11863 19951-19952 VBD denotes /
T11864 19952-19953 CD denotes −
T11865 19954-19958 NNS denotes mice
T11866 19958-19959 , denotes ,
T11867 19960-19963 CC denotes and
T11868 19964-19968 IN denotes that
T11869 19969-19972 DT denotes the
T11870 19973-19982 NN denotes elevation
T11871 19983-19985 IN denotes of
T11872 19986-19992 NN denotes IL-1Ra
T11873 19992-19993 , denotes ,
T11874 19994-20005 VBN denotes accompanied
T11875 20006-20010 IN denotes with
T11876 20011-20020 VBN denotes decreased
T11877 20021-20026 NNP denotes NF-κB
T11878 20026-20027 , denotes ,
T11879 20028-20030 VBZ denotes is
T11880 20031-20042 JJ denotes significant
T11881 20043-20045 IN denotes in
T11882 20046-20049 DT denotes the
T11883 20050-20060 NN denotes inhibition
T11884 20061-20063 IN denotes of
T11885 20064-20072 NN denotes melanoma
T11886 20073-20079 NN denotes growth
T11887 20080-20082 IN denotes in
T11888 20083-20087 CD denotes CCR5
T11889 20087-20088 CD denotes −
T11890 20088-20089 NN denotes /
T11891 20089-20090 NN denotes −
T11892 20091-20095 NNS denotes mice
T11893 20095-20096 . denotes .
T11894 20097-20102 JJ denotes NF-κB
T11895 20103-20112 VBZ denotes regulates
T11896 20113-20116 DT denotes the
T11897 20117-20127 NN denotes expression
T11898 20128-20130 IN denotes of
T11899 20131-20135 IN denotes over
T11900 20136-20139 CD denotes 200
T11901 20140-20145 NNS denotes genes
T11902 20146-20150 WDT denotes that
T11903 20151-20158 VBP denotes control
T11904 20159-20162 DT denotes the
T11905 20163-20169 JJ denotes immune
T11906 20170-20176 NN denotes system
T11907 20176-20177 , denotes ,
T11908 20178-20184 NN denotes cancer
T11909 20185-20189 NN denotes cell
T11910 20190-20196 NN denotes growth
T11911 20197-20200 CC denotes and
T11912 20201-20213 NN denotes inflammation
T11913 20214-20215 NNP denotes [
T11914 20215-20217 CD denotes 39
T11915 20217-20218 NNP denotes ]
T11916 20218-20219 . denotes .
T11917 20220-20227 IN denotes Because
T11918 20228-20230 IN denotes of
T11919 20231-20234 PRP$ denotes its
T11920 20235-20244 NNS denotes abilities
T11921 20245-20247 TO denotes to
T11922 20248-20254 VB denotes induce
T11923 20255-20258 DT denotes the
T11924 20259-20269 NN denotes expression
T11925 20270-20272 IN denotes of
T11926 20273-20274 DT denotes a
T11927 20275-20280 JJ denotes large
T11928 20281-20286 NN denotes array
T11929 20287-20289 IN denotes of
T11930 20290-20302 JJ denotes inflammatory
T11931 20303-20312 NNS denotes mediators
T11932 20313-20316 CC denotes and
T11933 20317-20320 PRP$ denotes its
T11934 20321-20326 NNS denotes roles
T11935 20327-20329 IN denotes as
T11936 20330-20334 NN denotes core
T11937 20335-20348 NN denotes transcription
T11938 20349-20356 NNS denotes factors
T11939 20357-20359 IN denotes in
T11940 20360-20367 JJ denotes diverse
T11941 20368-20374 JJ denotes immune
T11942 20375-20384 NNS denotes responses
T11943 20384-20385 , denotes ,
T11944 20386-20391 NNP denotes NF-κB
T11945 20392-20395 VBZ denotes has
T11946 20396-20400 VBN denotes been
T11947 20401-20411 VBN denotes recognized
T11948 20412-20414 IN denotes as
T11949 20415-20416 DT denotes a
T11950 20417-20422 JJ denotes major
T11951 20423-20429 NN denotes factor
T11952 20430-20441 JJ denotes responsible
T11953 20442-20445 IN denotes for
T11954 20446-20465 JJ denotes cytokine-associated
T11955 20466-20472 NN denotes cancer
T11956 20473-20484 NN denotes development
T11957 20485-20487 CC denotes or
T11958 20488-20498 JJ denotes anti-tumor
T11959 20499-20507 NN denotes immunity
T11960 20507-20508 . denotes .
T11961 20509-20511 IN denotes In
T11962 20512-20515 DT denotes the
T11963 20516-20524 NN denotes melanoma
T11964 20525-20530 NN denotes tumor
T11965 20531-20538 NNS denotes tissues
T11966 20539-20541 IN denotes of
T11967 20542-20545 DT denotes the
T11968 20546-20550 NNP denotes CCR5
T11969 20550-20551 NNP denotes −
T11970 20551-20552 VBD denotes /
T11971 20552-20553 CD denotes −
T11972 20554-20558 NNS denotes mice
T11973 20558-20559 , denotes ,
T11974 20560-20563 DT denotes the
T11975 20564-20574 NN denotes expression
T11976 20575-20577 IN denotes of
T11977 20578-20583 JJ denotes NF-κB
T11978 20584-20590 NN denotes target
T11979 20591-20595 NN denotes cell
T11980 20596-20601 NN denotes death
T11981 20602-20607 NNS denotes genes
T11982 20608-20609 -LRB- denotes (
T11983 20609-20612 NNP denotes Bax
T11984 20612-20613 , denotes ,
T11985 20614-20623 JJ denotes caspase-3
T11986 20624-20627 CC denotes and
T11987 20628-20629 CD denotes 9
T11988 20629-20630 -RRB- denotes )
T11989 20631-20634 CC denotes and
T11990 20635-20638 DT denotes the
T11991 20639-20642 NNP denotes DNA
T11992 20643-20650 JJ denotes binding
T11993 20651-20659 NN denotes activity
T11994 20660-20662 IN denotes of
T11995 20663-20668 NNP denotes NF-κB
T11996 20668-20669 , denotes ,
T11997 20670-20674 VBD denotes were
T11998 20675-20688 RB denotes significantly
T11999 20689-20698 VBN denotes inhibited
T12000 20698-20699 , denotes ,
T12001 20700-20703 CC denotes but
T12002 20704-20707 DT denotes the
T12003 20708-20718 NN denotes expression
T12004 20719-20721 IN denotes of
T12005 20722-20726 NN denotes cell
T12006 20727-20732 NN denotes death
T12007 20733-20743 JJ denotes inhibitory
T12008 20744-20749 NN denotes NF-κB
T12009 20750-20756 NN denotes target
T12010 20757-20762 NNS denotes genes
T12011 20762-20763 , denotes ,
T12012 20764-20768 JJ denotes such
T12013 20769-20771 IN denotes as
T12014 20772-20777 NN denotes Bcl-2
T12015 20778-20781 CC denotes and
T12016 20782-20786 NNP denotes cIAP
T12017 20787-20791 VBD denotes were
T12018 20792-20800 VBN denotes enhanced
T12019 20800-20801 . denotes .
T12020 20802-20804 IN denotes In
T12021 20805-20813 NN denotes addition
T12022 20813-20814 , denotes ,
T12023 20815-20819 NNP denotes CCR5
T12024 20819-20820 VBD denotes −
T12025 20820-20821 CD denotes /
T12026 20821-20822 NN denotes −
T12027 20823-20832 VBD denotes prevented
T12028 20833-20836 DT denotes the
T12029 20837-20852 NN denotes phosphorylation
T12030 20853-20855 IN denotes of
T12031 20856-20859 NNP denotes IκB
T12032 20859-20860 , denotes ,
T12033 20861-20872 VBN denotes accompanied
T12034 20873-20877 IN denotes with
T12035 20878-20881 DT denotes the
T12036 20882-20892 NN denotes inhibition
T12037 20893-20895 IN denotes of
T12038 20896-20899 DT denotes the
T12039 20900-20903 CD denotes p50
T12040 20904-20907 CC denotes and
T12041 20908-20911 CD denotes p65
T12042 20912-20925 NN denotes translocation
T12043 20926-20930 IN denotes into
T12044 20931-20934 DT denotes the
T12045 20935-20942 NN denotes nucleus
T12046 20943-20944 -LRB- denotes (
T12047 20944-20950 NN denotes Figure
T12048 20951-20955 NN denotes 2A-C
T12049 20955-20956 -RRB- denotes )
T12050 20956-20957 . denotes .
T12051 20958-20962 JJ denotes Many
T12052 20963-20969 NNS denotes tumors
T12053 20969-20970 , denotes ,
T12054 20971-20980 VBG denotes including
T12055 20981-20989 NN denotes melanoma
T12056 20989-20990 , denotes ,
T12057 20991-20995 VBP denotes have
T12058 20996-21005 VBN denotes increased
T12059 21006-21012 NNS denotes levels
T12060 21013-21015 IN denotes of
T12061 21016-21021 NNP denotes NF-κB
T12062 21022-21023 NNP denotes [
T12063 21023-21025 CD denotes 40
T12064 21025-21026 NNP denotes ]
T12065 21026-21027 , denotes ,
T12066 21028-21033 WDT denotes which
T12067 21034-21036 VBZ denotes is
T12068 21037-21043 JJ denotes likely
T12069 21044-21050 VBG denotes acting
T12070 21051-21053 IN denotes as
T12071 21054-21055 DT denotes a
T12072 21056-21064 NN denotes survival
T12073 21065-21071 NN denotes factor
T12074 21072-21075 IN denotes for
T12075 21076-21084 NN denotes melanoma
T12076 21085-21091 NN denotes growth
T12077 21091-21092 . denotes .
T12078 21093-21097 RB denotes Thus
T12079 21097-21098 , denotes ,
T12080 21099-21102 DT denotes the
T12081 21103-21114 NNS denotes inhibitions
T12082 21115-21117 IN denotes of
T12083 21118-21123 JJ denotes NF-κB
T12084 21124-21132 NN denotes activity
T12085 21133-21136 CC denotes and
T12086 21137-21140 DT denotes the
T12087 21141-21151 NN denotes expression
T12088 21152-21154 IN denotes of
T12089 21155-21161 NN denotes target
T12090 21162-21167 NNS denotes genes
T12091 21168-21171 VBP denotes are
T12092 21172-21180 JJ denotes critical
T12093 21181-21183 IN denotes in
T12094 21184-21187 DT denotes the
T12095 21188-21198 NN denotes inhibition
T12096 21199-21201 IN denotes of
T12097 21202-21207 NN denotes tumor
T12098 21208-21214 NN denotes growth
T12099 21215-21217 IN denotes in
T12100 21218-21222 CD denotes CCR5
T12101 21222-21223 CD denotes −
T12102 21223-21224 NN denotes /
T12103 21224-21225 NN denotes −
T12104 21226-21230 NNS denotes mice
T12105 21230-21231 . denotes .
T12106 21232-21240 IN denotes Although
T12107 21241-21244 DT denotes the
T12108 21245-21254 NN denotes mechanism
T12109 21255-21257 VBZ denotes is
T12110 21258-21261 RB denotes not
T12111 21262-21267 JJ denotes clear
T12112 21268-21270 IN denotes as
T12113 21271-21273 TO denotes to
T12114 21274-21277 WRB denotes how
T12115 21278-21282 NNP denotes CCR5
T12116 21282-21283 VBD denotes −
T12117 21283-21284 CD denotes /
T12118 21284-21285 NN denotes −
T12119 21286-21299 VBZ denotes downregulates
T12120 21300-21305 NNP denotes NF-κB
T12121 21305-21306 , denotes ,
T12122 21307-21309 PRP denotes it
T12123 21310-21312 VBZ denotes is
T12124 21313-21323 JJ denotes noteworthy
T12125 21324-21328 IN denotes that
T12126 21329-21334 NNP denotes NF-κB
T12127 21335-21337 VBZ denotes is
T12128 21338-21347 VBN denotes activated
T12129 21348-21350 CC denotes or
T12130 21351-21362 VBN denotes inactivated
T12131 21363-21365 IN denotes by
T12132 21366-21370 JJ denotes many
T12133 21371-21380 NNS denotes cytokines
T12134 21380-21381 . denotes .
T12135 21382-21390 JJ denotes Numerous
T12136 21391-21398 NNS denotes studies
T12137 21399-21405 VBD denotes showed
T12138 21406-21410 IN denotes that
T12139 21411-21419 JJ denotes cytokine
T12140 21420-21426 VB denotes affect
T12141 21427-21432 NN denotes tumor
T12142 21433-21439 NN denotes growth
T12143 21440-21442 IN denotes by
T12144 21443-21453 VBG denotes regulating
T12145 21454-21459 NNP denotes NF-κB
T12146 21459-21460 . denotes .
T12147 21461-21473 JJ denotes Inflammatory
T12148 21474-21483 NNS denotes cytokines
T12149 21483-21484 , denotes ,
T12150 21485-21494 VBG denotes including
T12151 21495-21499 NNP denotes IL-1
T12152 21499-21500 , denotes ,
T12153 21501-21505 NNP denotes IL-6
T12154 21506-21509 CC denotes and
T12155 21510-21514 NNP denotes IL-8
T12156 21514-21515 , denotes ,
T12157 21516-21524 VBP denotes activate
T12158 21525-21530 JJ denotes NF-κB
T12159 21531-21539 NNS denotes pathways
T12160 21540-21542 IN denotes in
T12161 21543-21548 NN denotes tumor
T12162 21549-21554 NNS denotes cells
T12163 21555-21556 NNP denotes [
T12164 21556-21558 CD denotes 41
T12165 21558-21559 NNP denotes ]
T12166 21559-21560 . denotes .
T12167 21561-21564 DT denotes The
T12168 21565-21576 NN denotes interleukin
T12169 21577-21579 CD denotes 10
T12170 21580-21581 -LRB- denotes (
T12171 21581-21586 NN denotes IL-10
T12172 21586-21587 -RRB- denotes )
T12173 21588-21590 VBZ denotes is
T12174 21591-21595 RB denotes well
T12175 21596-21601 VBN denotes known
T12176 21602-21604 IN denotes as
T12177 21605-21607 DT denotes an
T12178 21608-21618 JJ denotes anti-tumor
T12179 21619-21625 NN denotes factor
T12180 21626-21628 RB denotes as
T12181 21629-21633 RB denotes well
T12182 21634-21636 IN denotes as
T12183 21637-21639 DT denotes an
T12184 21640-21657 JJ denotes anti-inflammatory
T12185 21658-21664 NN denotes factor
T12186 21665-21666 NNP denotes [
T12187 21666-21668 CD denotes 42
T12188 21668-21669 NNP denotes ]
T12189 21669-21670 , denotes ,
T12190 21671-21672 NNP denotes [
T12191 21672-21674 CD denotes 43
T12192 21674-21675 NNP denotes ]
T12193 21675-21676 . denotes .
T12194 21677-21682 JJ denotes IL-10
T12195 21683-21691 NNS denotes inhibits
T12196 21692-21706 RB denotes constitutively
T12197 21707-21716 VBD denotes activated
T12198 21717-21722 NNP denotes NF-κB
T12199 21723-21727 DT denotes both
T12200 21728-21730 IN denotes in
T12201 21731-21736 NN denotes vitro
T12202 21737-21738 NNP denotes [
T12203 21738-21740 CD denotes 44
T12204 21740-21741 NNP denotes ]
T12205 21742-21745 CC denotes and
T12206 21746-21748 IN denotes in
T12207 21749-21753 NN denotes vivo
T12208 21754-21755 NNP denotes [
T12209 21755-21757 CD denotes 45
T12210 21757-21758 NNP denotes ]
T12211 21758-21759 . denotes .
T12212 21760-21770 NNP denotes Inhibition
T12213 21771-21773 IN denotes of
T12214 21774-21779 NNP denotes NF-κB
T12215 21780-21782 IN denotes by
T12216 21783-21786 DT denotes the
T12217 21787-21792 NNP denotes IL-10
T12218 21793-21804 VBZ denotes contributes
T12219 21805-21807 TO denotes to
T12220 21808-21811 DT denotes the
T12221 21812-21822 JJ denotes anti-tumor
T12222 21823-21830 NNS denotes effects
T12223 21831-21838 IN denotes through
T12224 21839-21842 DT denotes the
T12225 21843-21853 NN denotes activation
T12226 21854-21856 IN denotes of
T12227 21857-21866 JJ denotes caspase-3
T12228 21867-21870 CC denotes and
T12229 21871-21880 NN denotes apoptosis
T12230 21881-21883 IN denotes in
T12231 21884-21899 JJ denotes Colon26-bearing
T12232 21900-21904 NNS denotes mice
T12233 21905-21906 NNP denotes [
T12234 21906-21908 CD denotes 43
T12235 21908-21909 NNP denotes ]
T12236 21909-21910 . denotes .
T12237 21911-21920 RB denotes Similarly
T12238 21920-21921 , denotes ,
T12239 21922-21929 JJ denotes several
T12240 21930-21937 NNS denotes studies
T12241 21938-21942 VBP denotes have
T12242 21943-21955 VBN denotes demonstrated
T12243 21956-21959 DT denotes the
T12244 21960-21967 NN denotes ability
T12245 21968-21970 IN denotes of
T12246 21971-21977 NN denotes IL-1Ra
T12247 21978-21980 TO denotes to
T12248 21981-21989 VB denotes abrogate
T12249 21990-21993 DT denotes the
T12250 21994-22009 JJ denotes proinflammatory
T12251 22010-22017 NNS denotes effects
T12252 22018-22020 IN denotes of
T12253 22021-22025 NNP denotes IL-1
T12254 22026-22027 NNP denotes [
T12255 22027-22029 CD denotes 46
T12256 22029-22030 NNP denotes ]
T12257 22030-22031 . denotes .
T12258 22032-22034 PRP denotes It
T12259 22035-22038 VBZ denotes has
T12260 22039-22043 VBN denotes been
T12261 22044-22052 VBN denotes reported
T12262 22053-22057 IN denotes that
T12263 22058-22062 JJ denotes IL-1
T12264 22063-22070 VBZ denotes induces
T12265 22071-22074 DT denotes the
T12266 22075-22085 NN denotes activation
T12267 22086-22088 IN denotes of
T12268 22089-22094 NN denotes NF-κB
T12269 22095-22097 IN denotes in
T12270 22098-22105 JJ denotes several
T12271 22106-22113 NNS denotes cancers
T12272 22113-22114 , denotes ,
T12273 22115-22118 CC denotes and
T12274 22119-22128 VBZ denotes increases
T12275 22129-22133 NN denotes cell
T12276 22134-22139 NN denotes cycle
T12277 22140-22151 NN denotes progression
T12278 22151-22152 , denotes ,
T12279 22153-22156 CC denotes and
T12280 22157-22160 DT denotes the
T12281 22161-22172 NN denotes suppression
T12282 22173-22175 IN denotes of
T12283 22176-22185 JJ denotes apoptotic
T12284 22186-22190 NN denotes cell
T12285 22191-22196 NN denotes death
T12286 22197-22204 VBG denotes leading
T12287 22205-22207 TO denotes to
T12288 22208-22213 NN denotes tumor
T12289 22214-22223 NN denotes promotion
T12290 22223-22224 . denotes .
T12291 22225-22228 DT denotes The
T12292 22229-22236 NNS denotes results
T12293 22237-22239 IN denotes of
T12294 22240-22247 JJ denotes various
T12295 22248-22255 NNS denotes studies
T12296 22256-22260 IN denotes over
T12297 22261-22264 DT denotes the
T12298 22265-22269 JJ denotes past
T12299 22270-22272 CD denotes 10
T12300 22273-22278 NNS denotes years
T12301 22279-22287 VBP denotes indicate
T12302 22288-22292 IN denotes that
T12303 22293-22296 DT denotes the
T12304 22297-22302 JJ denotes major
T12305 22303-22311 NN denotes function
T12306 22312-22314 IN denotes of
T12307 22315-22321 NN denotes IL-1Ra
T12308 22322-22324 VBZ denotes is
T12309 22325-22327 TO denotes to
T12310 22328-22336 VB denotes regulate
T12311 22337-22340 DT denotes the
T12312 22341-22352 JJ denotes pleiotropic
T12313 22353-22360 NNS denotes effects
T12314 22361-22363 IN denotes of
T12315 22364-22368 NN denotes IL-1
T12316 22369-22371 IN denotes by
T12317 22372-22385 RB denotes competitively
T12318 22386-22394 VBG denotes blocking
T12319 22395-22398 PRP$ denotes its
T12320 22399-22408 NNS denotes functions
T12321 22409-22410 NNP denotes [
T12322 22410-22412 CD denotes 47
T12323 22412-22413 NNP denotes ]
T12324 22413-22414 . denotes .
T12325 22415-22418 DT denotes The
T12326 22419-22426 NN denotes ability
T12327 22427-22429 IN denotes of
T12328 22430-22434 NN denotes IL-1
T12329 22435-22437 TO denotes to
T12330 22438-22444 VB denotes induce
T12331 22445-22448 PRP$ denotes its
T12332 22449-22452 JJ denotes own
T12333 22453-22463 NN denotes antagonist
T12334 22464-22466 VBZ denotes is
T12335 22467-22469 IN denotes of
T12336 22470-22478 NN denotes interest
T12337 22479-22481 IN denotes in
T12338 22482-22495 VBG denotes understanding
T12339 22496-22499 DT denotes the
T12340 22500-22510 NN denotes regulation
T12341 22511-22514 CC denotes and
T12342 22515-22528 NN denotes dysregulation
T12343 22529-22531 IN denotes of
T12344 22532-22536 JJ denotes IL-1
T12345 22537-22546 VBG denotes signaling
T12346 22547-22549 IN denotes in
T12347 22550-22556 JJ denotes normal
T12348 22557-22560 CC denotes and
T12349 22561-22569 JJ denotes diseased
T12350 22570-22576 NN denotes tissue
T12351 22576-22577 . denotes .
T12352 22578-22591 NN denotes Up-regulation
T12353 22592-22594 IN denotes of
T12354 22595-22598 DT denotes the
T12355 22599-22607 NN denotes receptor
T12356 22608-22618 NN denotes antagonist
T12357 22619-22629 VBZ denotes represents
T12358 22630-22631 DT denotes a
T12359 22632-22641 NN denotes mechanism
T12360 22642-22645 IN denotes for
T12361 22646-22653 VBG denotes turning
T12362 22654-22657 RP denotes off
T12363 22658-22662 JJ denotes IL-1
T12364 22663-22672 VBG denotes signaling
T12365 22673-22676 CC denotes and
T12366 22677-22685 VBG denotes creating
T12367 22686-22687 DT denotes a
T12368 22688-22697 JJ denotes temporary
T12369 22698-22703 NN denotes state
T12370 22704-22706 IN denotes of
T12371 22707-22721 NN denotes refractoriness
T12372 22721-22722 . denotes .
T12373 22723-22726 DT denotes The
T12374 22727-22735 JJ denotes elevated
T12375 22736-22746 NN denotes expression
T12376 22747-22749 IN denotes of
T12377 22750-22756 NN denotes IL-1Ra
T12378 22756-22757 , denotes ,
T12379 22758-22765 IN denotes without
T12380 22766-22769 DT denotes any
T12381 22770-22776 NN denotes change
T12382 22777-22779 IN denotes of
T12383 22780-22784 NN denotes IL-1
T12384 22785-22787 IN denotes in
T12385 22788-22794 NNS denotes tumors
T12386 22794-22795 , denotes ,
T12387 22796-22804 VBZ denotes suggests
T12388 22805-22809 IN denotes that
T12389 22810-22813 DT denotes the
T12390 22814-22828 JJ denotes IL-1-signaling
T12391 22829-22835 NN denotes system
T12392 22836-22839 MD denotes may
T12393 22840-22842 VB denotes be
T12394 22843-22855 VBN denotes dysregulated
T12395 22856-22858 IN denotes by
T12396 22859-22865 NN denotes IL-1Ra
T12397 22866-22868 IN denotes in
T12398 22869-22875 NNS denotes tumors
T12399 22875-22876 . denotes .
T12400 22877-22883 NN denotes IL-1Ra
T12401 22884-22887 VBZ denotes has
T12402 22888-22892 VBN denotes been
T12403 22893-22898 VBN denotes shown
T12404 22899-22901 TO denotes to
T12405 22902-22909 VB denotes inhibit
T12406 22910-22915 NN denotes tumor
T12407 22916-22927 NN denotes progression
T12408 22928-22930 IN denotes in
T12409 22931-22939 NN denotes prostate
T12410 22939-22940 , denotes ,
T12411 22941-22947 NN denotes breast
T12412 22947-22948 , denotes ,
T12413 22949-22952 CC denotes and
T12414 22953-22957 NN denotes skin
T12415 22958-22964 NN denotes cancer
T12416 22965-22966 NNP denotes [
T12417 22966-22968 CD denotes 14
T12418 22968-22969 NNP denotes ]
T12419 22969-22970 , denotes ,
T12420 22971-22972 NNP denotes [
T12421 22972-22974 CD denotes 15
T12422 22974-22975 NNP denotes ]
T12423 22975-22976 , denotes ,
T12424 22977-22978 NNP denotes [
T12425 22978-22980 CD denotes 16
T12426 22980-22981 NNP denotes ]
T12427 22981-22982 . denotes .
T12428 22983-22996 JJ denotes Intracellular
T12429 22997-23003 NN denotes IL-1Ra
T12430 23004-23005 -LRB- denotes (
T12431 23005-23013 NN denotes icIL-1Ra
T12432 23013-23014 -RRB- denotes )
T12433 23015-23023 VBZ denotes inhibits
T12434 23024-23028 NNP denotes IL-6
T12435 23029-23032 CC denotes and
T12436 23033-23037 JJ denotes IL-8
T12437 23038-23048 NN denotes production
T12438 23049-23051 IN denotes in
T12439 23052-23058 JJ denotes Caco-2
T12440 23059-23064 NNS denotes cells
T12441 23065-23067 IN denotes by
T12442 23068-23076 VBG denotes blocking
T12443 23077-23082 JJ denotes NF-κB
T12444 23083-23091 NNS denotes pathways
T12445 23092-23093 NNP denotes [
T12446 23093-23095 CD denotes 37
T12447 23095-23096 NNP denotes ]
T12448 23096-23097 . denotes .
T12449 23098-23100 PRP denotes We
T12450 23101-23106 VBD denotes found
T12451 23107-23111 IN denotes that
T12452 23112-23115 DT denotes the
T12453 23116-23122 NNS denotes levels
T12454 23123-23125 IN denotes of
T12455 23126-23132 NN denotes IL-1Ra
T12456 23133-23137 VBD denotes were
T12457 23138-23151 RB denotes significantly
T12458 23152-23160 VBN denotes elevated
T12459 23161-23163 IN denotes in
T12460 23164-23167 DT denotes the
T12461 23168-23173 NN denotes tumor
T12462 23174-23181 NNS denotes tissues
T12463 23182-23184 IN denotes of
T12464 23185-23189 CD denotes CCR5
T12465 23189-23190 CD denotes −
T12466 23190-23191 NN denotes /
T12467 23191-23192 NN denotes −
T12468 23193-23197 NNS denotes mice
T12469 23198-23208 VBN denotes inoculated
T12470 23209-23213 IN denotes with
T12471 23214-23217 NNP denotes B16
T12472 23218-23226 NN denotes melanoma
T12473 23227-23232 NNS denotes cells
T12474 23232-23233 . denotes .
T12475 23234-23239 VBN denotes Taken
T12476 23240-23248 RB denotes together
T12477 23248-23249 , denotes ,
T12478 23250-23255 DT denotes these
T12479 23256-23260 NNS denotes data
T12480 23261-23269 VBP denotes indicate
T12481 23270-23276 NN denotes IL-1Ra
T12482 23277-23282 MD denotes could
T12483 23283-23285 VB denotes be
T12484 23286-23296 RB denotes critically
T12485 23297-23305 VBN denotes involved
T12486 23306-23308 IN denotes in
T12487 23309-23312 DT denotes the
T12488 23313-23318 NN denotes tumor
T12489 23319-23325 NN denotes growth
T12490 23326-23336 NN denotes inhibition
T12491 23337-23339 IN denotes of
T12492 23340-23344 CD denotes CCR5
T12493 23344-23345 CD denotes −
T12494 23345-23346 NN denotes /
T12495 23346-23347 NN denotes −
T12496 23348-23352 NNS denotes mice
T12497 23353-23360 IN denotes through
T12498 23361-23364 DT denotes the
T12499 23365-23377 NN denotes inactivation
T12500 23378-23380 IN denotes of
T12501 23381-23386 NN denotes NF-κB
T12502 23387-23389 IN denotes in
T12503 23390-23393 DT denotes the
T12504 23394-23401 JJ denotes present
T12505 23402-23407 NN denotes study
T12506 23407-23408 . denotes .
T12507 23409-23413 CD denotes CCR5
T12508 23414-23423 NNS denotes increases
T12509 23424-23429 NN denotes tumor
T12510 23430-23436 NN denotes growth
T12511 23437-23439 IN denotes in
T12512 23440-23441 DT denotes a
T12513 23442-23447 JJ denotes local
T12514 23448-23453 NN denotes model
T12515 23454-23457 CC denotes and
T12516 23458-23466 VBZ denotes inhibits
T12517 23467-23470 DT denotes the
T12518 23471-23479 NN denotes efficacy
T12519 23480-23482 IN denotes of
T12520 23483-23484 DT denotes a
T12521 23485-23493 JJ denotes dendrite
T12522 23494-23498 NN denotes cell
T12523 23499-23506 NN denotes vaccine
T12524 23507-23509 IN denotes in
T12525 23510-23514 CD denotes CCR5
T12526 23514-23515 CD denotes +
T12527 23515-23516 NN denotes /
T12528 23516-23517 NN denotes +
T12529 23518-23522 NNS denotes mice
T12530 23523-23531 VBN denotes compared
T12531 23532-23536 IN denotes with
T12532 23537-23541 CD denotes CCR5
T12533 23541-23542 CD denotes −
T12534 23542-23543 NN denotes /
T12535 23543-23544 NN denotes −
T12536 23545-23549 NNS denotes mice
T12537 23550-23551 NNP denotes [
T12538 23551-23553 CD denotes 10
T12539 23553-23554 NNP denotes ]
T12540 23554-23555 . denotes .
T12541 23556-23561 NNP denotes Cheng
T12542 23562-23563 NNP denotes J
T12543 23564-23567 CC denotes and
T12544 23568-23572 NNP denotes Sung
T12545 23573-23575 NNP denotes RS
T12546 23576-23584 VBD denotes examined
T12547 23585-23588 DT denotes the
T12548 23589-23595 NN denotes effect
T12549 23596-23598 IN denotes of
T12550 23599-23603 NNS denotes CCR5
T12551 23604-23606 IN denotes on
T12552 23607-23610 DT denotes the
T12553 23611-23617 JJ denotes immune
T12554 23618-23626 NN denotes response
T12555 23627-23629 TO denotes to
T12556 23630-23640 NN denotes adenovirus
T12557 23641-23648 NNS denotes vectors
T12558 23649-23652 CC denotes and
T12559 23653-23658 NN denotes graft
T12560 23659-23667 NN denotes function
T12561 23668-23670 IN denotes in
T12562 23671-23673 DT denotes an
T12563 23674-23679 NN denotes islet
T12564 23680-23690 NN denotes transplant
T12565 23691-23696 NN denotes model
T12566 23696-23697 . denotes .
T12567 23698-23702 PRP denotes They
T12568 23703-23708 VBD denotes found
T12569 23709-23713 IN denotes that
T12570 23714-23718 CD denotes CCR5
T12571 23719-23726 NN denotes absence
T12572 23727-23731 VBZ denotes does
T12573 23732-23735 RB denotes not
T12574 23736-23743 VB denotes prevent
T12575 23744-23747 DT denotes the
T12576 23748-23753 JJ denotes local
T12577 23754-23760 JJ denotes immune
T12578 23761-23769 NN denotes response
T12579 23770-23772 TO denotes to
T12580 23773-23783 NN denotes adenovirus
T12581 23784-23796 NN denotes transduction
T12582 23797-23798 NNP denotes [
T12583 23798-23800 CD denotes 48
T12584 23800-23801 NNP denotes ]
T12585 23801-23802 . denotes .
T12586 23803-23815 RB denotes Additionally
T12587 23815-23816 , denotes ,
T12588 23817-23820 NNP denotes Tan
T12589 23821-23823 NNP denotes MC
T12590 23824-23826 FW denotes et
T12591 23827-23830 FW denotes al.
T12592 23831-23840 VBD denotes suggested
T12593 23841-23845 IN denotes that
T12594 23846-23856 NN denotes disruption
T12595 23857-23859 IN denotes of
T12596 23860-23869 CD denotes CCR5/CCL5
T12597 23870-23879 VBG denotes signaling
T12598 23879-23880 , denotes ,
T12599 23881-23887 RB denotes either
T12600 23888-23890 IN denotes by
T12601 23891-23899 VBG denotes reducing
T12602 23900-23904 CD denotes CCL5
T12603 23905-23915 NN denotes production
T12604 23916-23918 IN denotes by
T12605 23919-23924 NN denotes tumor
T12606 23925-23930 NNS denotes cells
T12607 23931-23933 CC denotes or
T12608 23934-23936 IN denotes by
T12609 23937-23945 JJ denotes systemic
T12610 23946-23960 NN denotes administration
T12611 23961-23963 IN denotes of
T12612 23964-23965 DT denotes a
T12613 23966-23970 NNP denotes CCR5
T12614 23971-23980 NN denotes inhibitor
T12615 23981-23982 -LRB- denotes (
T12616 23982-23989 CD denotes TAK-779
T12617 23989-23990 -RRB- denotes )
T12618 23990-23991 , denotes ,
T12619 23992-23999 VBN denotes reduced
T12620 24000-24004 NNP denotes Treg
T12621 24005-24006 -LRB- denotes (
T12622 24006-24016 JJ denotes regulatory
T12623 24017-24018 NNP denotes T
T12624 24019-24024 NNS denotes cells
T12625 24024-24025 -RRB- denotes )
T12626 24026-24035 NN denotes migration
T12627 24036-24038 TO denotes to
T12628 24039-24045 NNS denotes tumors
T12629 24046-24048 IN denotes so
T12630 24049-24053 IN denotes that
T12631 24054-24060 NNS denotes tumors
T12632 24061-24064 VBP denotes are
T12633 24065-24072 JJR denotes smaller
T12634 24073-24075 IN denotes in
T12635 24076-24083 NN denotes control
T12636 24084-24088 NNS denotes mice
T12637 24089-24090 VBP denotes [
T12638 24090-24091 CD denotes 9
T12639 24091-24092 NNP denotes ]
T12640 24092-24093 . denotes .
T12641 24094-24099 DT denotes These
T12642 24100-24104 NNS denotes data
T12643 24105-24112 VBP denotes support
T12644 24113-24116 DT denotes the
T12645 24117-24126 JJ denotes important
T12646 24127-24134 NN denotes premise
T12647 24135-24139 WDT denotes that
T12648 24140-24150 NN denotes inhibition
T12649 24151-24153 IN denotes of
T12650 24154-24159 NN denotes tumor
T12651 24160-24166 NN denotes growth
T12652 24167-24169 IN denotes in
T12653 24170-24174 CD denotes CCR5
T12654 24174-24175 CD denotes −
T12655 24175-24176 NN denotes /
T12656 24176-24177 NN denotes −
T12657 24178-24182 NNS denotes mice
T12658 24183-24188 MD denotes could
T12659 24189-24191 VB denotes be
T12660 24192-24199 VBN denotes related
T12661 24200-24204 IN denotes with
T12662 24205-24208 DT denotes the
T12663 24209-24219 NN denotes inhibition
T12664 24220-24222 IN denotes of
T12665 24223-24229 JJ denotes immune
T12666 24230-24236 NN denotes escape
T12667 24236-24237 . denotes .
T12668 24238-24245 JJ denotes Similar
T12669 24246-24248 TO denotes to
T12670 24249-24253 DT denotes this
T12671 24254-24261 NN denotes finding
T12672 24261-24262 , denotes ,
T12673 24263-24265 PRP denotes we
T12674 24266-24271 VBD denotes found
T12675 24272-24276 IN denotes that
T12676 24277-24280 DT denotes the
T12677 24281-24285 NNP denotes CCR5
T12678 24285-24286 NNP denotes +
T12679 24286-24287 VBD denotes /
T12680 24287-24288 CD denotes +
T12681 24289-24293 NNS denotes mice
T12682 24294-24302 VBN denotes injected
T12683 24303-24307 IN denotes with
T12684 24308-24316 NN denotes melanoma
T12685 24317-24322 NNS denotes cells
T12686 24323-24333 RB denotes apparently
T12687 24334-24338 VBP denotes have
T12688 24339-24340 DT denotes a
T12689 24341-24346 JJR denotes lower
T12690 24347-24353 NN denotes number
T12691 24354-24356 IN denotes of
T12692 24357-24366 JJ denotes cytotoxic
T12693 24367-24368 NNP denotes T
T12694 24369-24374 NNS denotes cells
T12695 24375-24376 -LRB- denotes (
T12696 24376-24379 CD denotes CD8
T12697 24379-24380 NN denotes +
T12698 24380-24388 JJ denotes positive
T12699 24389-24390 NNP denotes T
T12700 24391-24402 NNP denotes Lymphocytes
T12701 24403-24408 NNS denotes cells
T12702 24408-24409 -RRB- denotes )
T12703 24410-24413 CC denotes and
T12704 24414-24421 JJ denotes natural
T12705 24422-24428 NN denotes killer
T12706 24429-24434 NNS denotes cells
T12707 24435-24436 -LRB- denotes (
T12708 24436-24440 NNP denotes CD57
T12709 24441-24449 JJ denotes positive
T12710 24450-24452 NNP denotes NK
T12711 24453-24458 NNS denotes cells
T12712 24458-24459 -RRB- denotes )
T12713 24459-24460 , denotes ,
T12714 24461-24463 RB denotes as
T12715 24464-24468 RB denotes well
T12716 24469-24471 IN denotes as
T12717 24472-24480 JJ denotes dendrite
T12718 24481-24486 NNS denotes cells
T12719 24486-24487 , denotes ,
T12720 24488-24490 IN denotes in
T12721 24491-24497 JJ denotes spleen
T12722 24498-24505 NNS denotes tissues
T12723 24506-24514 VBN denotes compared
T12724 24515-24517 TO denotes to
T12725 24518-24523 DT denotes those
T12726 24524-24531 IN denotes without
T12727 24532-24540 NN denotes melanoma
T12728 24541-24546 NNS denotes cells
T12729 24546-24547 . denotes .
T12730 24548-24551 CC denotes But
T12731 24552-24555 DT denotes the
T12732 24556-24567 NNS denotes lymphocytes
T12733 24568-24570 IN denotes of
T12734 24571-24574 DT denotes the
T12735 24575-24579 NNP denotes CCR5
T12736 24579-24580 NNP denotes −
T12737 24580-24581 VBD denotes /
T12738 24581-24582 CD denotes −
T12739 24583-24587 NNS denotes mice
T12740 24588-24591 VBD denotes did
T12741 24592-24595 RB denotes not
T12742 24596-24604 VB denotes decrease
T12743 24605-24609 WRB denotes when
T12744 24610-24618 VBN denotes injected
T12745 24619-24623 IN denotes with
T12746 24624-24632 NN denotes melanoma
T12747 24633-24638 NNS denotes cells
T12748 24638-24639 . denotes .
T12749 24640-24645 DT denotes These
T12750 24646-24657 NNS denotes differences
T12751 24658-24660 IN denotes of
T12752 24661-24664 DT denotes the
T12753 24665-24671 JJ denotes immune
T12754 24672-24680 NN denotes response
T12755 24681-24688 IN denotes between
T12756 24689-24692 DT denotes the
T12757 24693-24697 NNP denotes CCR5
T12758 24697-24698 NNP denotes +
T12759 24698-24699 VBD denotes /
T12760 24699-24700 CD denotes +
T12761 24701-24705 NNS denotes mice
T12762 24706-24709 CC denotes and
T12763 24710-24713 DT denotes the
T12764 24714-24718 NNP denotes CCR5
T12765 24718-24719 NNP denotes −
T12766 24719-24720 VBD denotes /
T12767 24720-24721 CD denotes −
T12768 24722-24726 NNS denotes mice
T12769 24726-24727 , denotes ,
T12770 24728-24737 VBG denotes involving
T12771 24738-24743 NN denotes tumor
T12772 24744-24750 JJ denotes immune
T12773 24751-24760 NN denotes tolerance
T12774 24760-24761 , denotes ,
T12775 24762-24765 MD denotes may
T12776 24766-24768 VB denotes be
T12777 24769-24778 VBN denotes connected
T12778 24779-24783 IN denotes with
T12779 24784-24787 DT denotes the
T12780 24788-24798 NN denotes inhibition
T12781 24799-24801 IN denotes of
T12782 24802-24808 NN denotes cancer
T12783 24809-24820 NN denotes progression
T12784 24820-24821 . denotes .
T12785 24822-24827 VBN denotes Taken
T12786 24828-24836 RB denotes together
T12787 24836-24837 , denotes ,
T12788 24838-24840 IN denotes in
T12789 24841-24844 DT denotes the
T12790 24845-24853 NN denotes cytokine
T12791 24854-24859 NN denotes array
T12792 24860-24870 NN denotes experiment
T12793 24870-24871 , denotes ,
T12794 24872-24875 DT denotes the
T12795 24876-24881 NN denotes level
T12796 24882-24884 IN denotes of
T12797 24885-24891 NNP denotes MIP-1α
T12798 24892-24893 -LRB- denotes (
T12799 24893-24898 WDT denotes which
T12800 24899-24902 VBZ denotes has
T12801 24903-24904 DT denotes a
T12802 24905-24911 JJ denotes potent
T12803 24912-24920 NN denotes activity
T12804 24921-24923 IN denotes of
T12805 24924-24925 NNP denotes T
T12806 24926-24930 NN denotes cell
T12807 24931-24934 CC denotes and
T12808 24935-24936 NNP denotes B
T12809 24937-24941 NN denotes cell
T12810 24942-24951 NN denotes migration
T12811 24951-24952 -RRB- denotes )
T12812 24953-24956 VBD denotes was
T12813 24957-24966 VBN denotes increased
T12814 24967-24969 IN denotes in
T12815 24970-24973 DT denotes the
T12816 24974-24978 NNP denotes CCR5
T12817 24978-24979 NNP denotes −
T12818 24979-24980 VBD denotes /
T12819 24980-24981 CD denotes −
T12820 24982-24986 NNS denotes mice
T12821 24987-24995 VBN denotes compared
T12822 24996-25000 IN denotes with
T12823 25001-25006 DT denotes those
T12824 25007-25009 IN denotes in
T12825 25010-25013 DT denotes the
T12826 25014-25018 NNP denotes CCR5
T12827 25018-25019 NNP denotes +
T12828 25019-25020 VBD denotes /
T12829 25020-25021 CD denotes +
T12830 25022-25026 NNS denotes mice
T12831 25026-25027 . denotes .
T12832 25028-25032 RB denotes Thus
T12833 25032-25033 , denotes ,
T12834 25034-25044 RB denotes relatively
T12835 25045-25054 VBD denotes increased
T12836 25055-25060 NN denotes tumor
T12837 25061-25071 VBN denotes associated
T12838 25072-25081 JJ denotes cytotoxic
T12839 25082-25093 NNS denotes lymphocytes
T12840 25094-25099 MD denotes could
T12841 25100-25104 VB denotes play
T12842 25105-25107 DT denotes an
T12843 25108-25117 JJ denotes important
T12844 25118-25122 NN denotes role
T12845 25123-25125 IN denotes in
T12846 25126-25136 VBG denotes inhibiting
T12847 25137-25140 DT denotes the
T12848 25141-25146 NN denotes tumor
T12849 25147-25153 NN denotes growth
T12850 25154-25156 IN denotes in
T12851 25157-25161 CD denotes CCR5
T12852 25161-25162 CD denotes −
T12853 25162-25163 NN denotes /
T12854 25163-25164 NN denotes −
T12855 25165-25169 NNS denotes mice
T12856 25169-25170 . denotes .
T12857 25171-25181 NNP denotes Activation
T12858 25182-25184 IN denotes of
T12859 25185-25190 NNP denotes NF-κB
T12860 25191-25196 MD denotes could
T12861 25197-25205 VB denotes modulate
T12862 25206-25217 JJ denotes subcellular
T12863 25218-25230 NN denotes localization
T12864 25231-25233 IN denotes of
T12865 25234-25236 NNP denotes NK
T12866 25237-25242 NNS denotes cells
T12867 25243-25246 CC denotes and
T12868 25247-25259 NN denotes pathogenesis
T12869 25260-25261 NNP denotes [
T12870 25261-25263 CD denotes 49
T12871 25263-25264 NNP denotes ]
T12872 25264-25265 . denotes .
T12873 25266-25276 NNP denotes Inhibition
T12874 25277-25279 IN denotes of
T12875 25280-25285 NNP denotes NF-κB
T12876 25286-25294 NN denotes activity
T12877 25295-25304 VBD denotes prevented
T12878 25305-25307 NNP denotes NK
T12879 25308-25312 NN denotes cell
T12880 25313-25322 NN denotes depletion
T12881 25322-25323 , denotes ,
T12882 25324-25327 CC denotes and
T12883 25328-25332 RB denotes thus
T12884 25333-25342 VBD denotes increased
T12885 25343-25353 JJ denotes anti-tumor
T12886 25354-25362 NN denotes activity
T12887 25363-25365 IN denotes by
T12888 25366-25376 VBG denotes decreasing
T12889 25377-25381 NN denotes IL-6
T12890 25382-25392 NN denotes production
T12891 25393-25394 NNP denotes [
T12892 25394-25396 CD denotes 50
T12893 25396-25397 NNP denotes ]
T12894 25397-25398 . denotes .
T12895 25399-25403 RB denotes Thus
T12896 25403-25404 , denotes ,
T12897 25405-25408 DT denotes the
T12898 25409-25418 VBN denotes decreased
T12899 25419-25424 NN denotes NF-κB
T12900 25425-25428 CC denotes and
T12901 25429-25437 VBD denotes elevated
T12902 25438-25444 NN denotes IL-1Ra
T12903 25445-25450 MD denotes could
T12904 25451-25455 RB denotes also
T12905 25456-25458 VB denotes be
T12906 25459-25469 VBN denotes associated
T12907 25470-25472 IN denotes in
T12908 25473-25476 DT denotes the
T12909 25477-25489 NN denotes infiltration
T12910 25490-25492 IN denotes of
T12911 25493-25502 JJ denotes cytotoxic
T12912 25503-25514 NNS denotes lymphocytes
T12913 25515-25519 IN denotes into
T12914 25520-25525 NN denotes tumor
T12915 25525-25526 , denotes ,
T12916 25527-25536 VBG denotes resulting
T12917 25537-25539 IN denotes in
T12918 25540-25545 NN denotes tumor
T12919 25546-25552 NN denotes growth
T12920 25553-25563 NN denotes inhibition
T12921 25563-25564 . denotes .
T12922 25565-25567 IN denotes In
T12923 25568-25576 NN denotes contrast
T12924 25576-25577 , denotes ,
T12925 25578-25583 NN denotes IL-23
T12926 25583-25584 , denotes ,
T12927 25585-25586 DT denotes a
T12928 25587-25592 NN denotes tumor
T12929 25593-25599 NN denotes growth
T12930 25600-25609 VBG denotes promoting
T12931 25610-25618 NN denotes cytokine
T12932 25618-25619 , denotes ,
T12933 25620-25629 VBD denotes increased
T12934 25630-25635 NNP denotes NF-κB
T12935 25636-25639 CC denotes and
T12936 25640-25646 JJ denotes immune
T12937 25647-25651 NN denotes cell
T12938 25652-25664 NN denotes infiltration
T12939 25665-25667 IN denotes in
T12940 25668-25672 JJ denotes oral
T12941 25673-25678 NN denotes tumor
T12942 25679-25680 NNP denotes [
T12943 25680-25682 CD denotes 51
T12944 25682-25683 NNP denotes ]
T12945 25683-25684 . denotes .
T12946 25685-25690 DT denotes These
T12947 25691-25695 NNS denotes data
T12948 25696-25704 VBP denotes indicate
T12949 25705-25709 IN denotes that
T12950 25710-25715 NN denotes NF-κB
T12951 25716-25721 MD denotes could
T12952 25722-25724 VB denotes be
T12953 25725-25733 VBN denotes involved
T12954 25734-25736 IN denotes in
T12955 25737-25740 DT denotes the
T12956 25741-25749 NN denotes cytokine
T12957 25750-25758 VBD denotes mediated
T12958 25759-25769 JJ denotes anti-tumor
T12959 25770-25780 NNS denotes activities
T12960 25781-25783 IN denotes of
T12961 25784-25790 JJ denotes immune
T12962 25791-25796 NNS denotes cells
T12963 25796-25797 . denotes .
T12964 25798-25800 PRP denotes It
T12965 25801-25803 VBZ denotes is
T12966 25804-25808 RB denotes also
T12967 25809-25819 JJ denotes noteworthy
T12968 25820-25824 IN denotes that
T12969 25825-25831 JJ denotes IL-1Ra
T12970 25832-25841 VBN denotes inhibited
T12971 25842-25850 NN denotes melanoma
T12972 25851-25856 NN denotes tumor
T12973 25857-25863 NN denotes growth
T12974 25864-25866 IN denotes by
T12975 25867-25877 VBG denotes increasing
T12976 25878-25881 DT denotes the
T12977 25882-25888 NN denotes number
T12978 25889-25891 IN denotes of
T12979 25892-25899 JJ denotes myeloid
T12980 25900-25910 NN denotes suppressor
T12981 25911-25916 NNS denotes cells
T12982 25917-25919 IN denotes in
T12983 25920-25925 NN denotes tumor
T12984 25926-25927 NNP denotes [
T12985 25927-25929 CD denotes 25
T12986 25929-25930 NNP denotes ]
T12987 25930-25931 . denotes .
T12988 25932-25935 DT denotes The
T12989 25936-25962 JJ denotes 3-methylcholatrene-induced
T12990 25963-25968 NN denotes tumor
T12991 25969-25978 NN denotes incidence
T12992 25979-25982 VBD denotes was
T12993 25983-25990 VBN denotes reduced
T12994 25991-25993 IN denotes in
T12995 25994-25999 JJ denotes IL-1α
T12996 26000-26008 NN denotes knockout
T12997 26009-26013 NNS denotes mice
T12998 26013-26014 , denotes ,
T12999 26015-26018 CC denotes but
T13000 26019-26028 VBD denotes increased
T13001 26029-26031 IN denotes in
T13002 26032-26038 NN denotes IL-1Ra
T13003 26039-26043 NNS denotes mice
T13004 26044-26048 IN denotes with
T13005 26049-26060 JJ denotes concomitant
T13006 26061-26071 NN denotes maturation
T13007 26072-26074 IN denotes of
T13008 26075-26077 NNP denotes NK
T13009 26078-26083 NNS denotes cells
T13010 26084-26087 CC denotes and
T13011 26088-26098 JJ denotes anti-tumor
T13012 26099-26107 NN denotes immunity
T13013 26108-26109 NNP denotes [
T13014 26109-26111 CD denotes 52
T13015 26111-26112 NNP denotes ]
T13016 26112-26113 . denotes .
T13017 26114-26119 DT denotes These
T13018 26120-26124 NNS denotes data
T13019 26125-26133 VBP denotes indicate
T13020 26134-26138 IN denotes that
T13021 26139-26142 DT denotes the
T13022 26143-26151 NN denotes decrease
T13023 26152-26154 IN denotes of
T13024 26155-26160 NNP denotes NF-κB
T13025 26160-26161 , denotes ,
T13026 26162-26165 CC denotes and
T13027 26166-26170 RB denotes thus
T13028 26171-26179 NN denotes increase
T13029 26180-26182 IN denotes of
T13030 26183-26189 NN denotes IL-1Ra
T13031 26190-26195 MD denotes could
T13032 26196-26198 VB denotes be
T13033 26199-26210 JJ denotes significant
T13034 26211-26213 IN denotes in
T13035 26214-26219 NN denotes tumor
T13036 26220-26226 NN denotes growth
T13037 26227-26237 NN denotes inhibition
T13038 26238-26240 IN denotes of
T13039 26241-26245 CD denotes CCR5
T13040 26245-26246 CD denotes −
T13041 26246-26247 NN denotes /
T13042 26247-26248 NN denotes −
T13043 26249-26253 NNS denotes mice
T13044 26253-26254 . denotes .
T13045 26255-26258 PRP$ denotes Our
T13046 26259-26263 NNS denotes data
T13047 26264-26268 RB denotes thus
T13048 26269-26273 VBP denotes show
T13049 26274-26285 JJ denotes significant
T13050 26286-26294 JJ denotes clinical
T13051 26295-26307 NNS denotes implications
T13052 26308-26310 IN denotes of
T13053 26311-26315 NNP denotes CCR5
T13054 26315-26316 , denotes ,
T13055 26317-26324 IN denotes because
T13056 26325-26329 NNP denotes CCR5
T13057 26330-26332 VBZ denotes is
T13058 26333-26334 DT denotes a
T13059 26335-26336 NNP denotes G
T13060 26337-26344 NN denotes protein
T13061 26345-26352 VBN denotes coupled
T13062 26353-26361 NN denotes receptor
T13063 26362-26365 CC denotes and
T13064 26366-26368 PRP denotes it
T13065 26369-26371 VBZ denotes is
T13066 26372-26380 JJ denotes amenable
T13067 26381-26383 TO denotes to
T13068 26384-26387 VB denotes use
T13069 26388-26390 IN denotes as
T13070 26391-26392 DT denotes a
T13071 26393-26398 JJ denotes small
T13072 26399-26407 NN denotes molecule
T13073 26408-26411 IN denotes for
T13074 26412-26415 DT denotes the
T13075 26416-26426 NN denotes inhibition
T13076 26427-26429 IN denotes of
T13077 26430-26434 NNP denotes CCR5
T13078 26434-26435 . denotes .
T13079 26436-26443 JJ denotes Several
T13080 26444-26448 JJ denotes such
T13081 26449-26458 NNS denotes compounds
T13082 26459-26463 VBP denotes have
T13083 26464-26471 RB denotes already
T13084 26472-26476 VBN denotes been
T13085 26477-26482 VBN denotes shown
T13086 26483-26485 TO denotes to
T13087 26486-26488 VB denotes be
T13088 26489-26493 JJ denotes safe
T13089 26494-26496 IN denotes in
T13090 26497-26505 JJ denotes clinical
T13091 26506-26512 NNS denotes trials
T13092 26513-26516 IN denotes for
T13093 26517-26520 NN denotes use
T13094 26521-26523 IN denotes in
T13095 26524-26531 JJ denotes certain
T13096 26532-26540 NNS denotes diseases
T13097 26541-26545 JJ denotes such
T13098 26546-26548 IN denotes as
T13099 26549-26552 NNP denotes HIV
T13100 26553-26554 NNP denotes [
T13101 26554-26556 CD denotes 53
T13102 26556-26557 NNP denotes ]
T13103 26557-26558 . denotes .
T13104 26559-26563 RB denotes Thus
T13105 26563-26564 , denotes ,
T13106 26565-26567 PRP denotes we
T13107 26568-26575 VBP denotes believe
T13108 26576-26580 NNP denotes CCR5
T13109 26581-26583 VBZ denotes is
T13110 26584-26585 DT denotes a
T13111 26586-26592 NN denotes cancer
T13112 26593-26599 NN denotes target
T13113 26600-26604 WDT denotes that
T13114 26605-26613 VBZ denotes warrants
T13115 26614-26623 VBN denotes continued
T13116 26624-26637 NN denotes investigation
T13117 26637-26638 . denotes .
T13118 26639-26641 IN denotes In
T13119 26642-26649 NN denotes summary
T13120 26649-26650 , denotes ,
T13121 26651-26655 DT denotes this
T13122 26656-26661 NN denotes study
T13123 26662-26668 VBD denotes showed
T13124 26669-26673 IN denotes that
T13125 26674-26682 NN denotes melanoma
T13126 26683-26688 NNS denotes cells
T13127 26689-26695 NN denotes growth
T13128 26696-26699 VBD denotes was
T13129 26700-26709 VBN denotes inhibited
T13130 26710-26713 IN denotes via
T13131 26714-26724 NN denotes modulation
T13132 26725-26727 IN denotes of
T13133 26728-26733 NNP denotes NF-κB
T13134 26733-26734 NNP denotes /
T13135 26734-26740 NNP denotes IL-1Ra
T13136 26741-26749 NNS denotes pathways
T13137 26750-26752 IN denotes in
T13138 26753-26757 CD denotes CCR5
T13139 26757-26758 CD denotes −
T13140 26758-26759 NN denotes /
T13141 26759-26760 NN denotes −
T13142 26761-26765 NNS denotes mice
T13143 26765-26766 . denotes .
T13242 26791-26797 NNS denotes Ethics
T13243 26798-26807 NNP denotes Statement
T13244 26808-26811 NNP denotes All
T13245 26812-26823 NNS denotes experiments
T13246 26824-26828 VBD denotes were
T13247 26829-26837 VBN denotes approved
T13248 26838-26841 CC denotes and
T13249 26842-26849 VBN denotes carried
T13250 26850-26853 RP denotes out
T13251 26854-26863 VBG denotes according
T13252 26864-26866 TO denotes to
T13253 26867-26870 DT denotes the
T13254 26871-26876 NNP denotes Guide
T13255 26877-26880 IN denotes for
T13256 26881-26884 DT denotes the
T13257 26885-26889 NNP denotes Care
T13258 26890-26893 CC denotes and
T13259 26894-26897 NNP denotes Use
T13260 26898-26900 IN denotes of
T13261 26901-26908 NNPS denotes Animals
T13262 26909-26910 NNP denotes [
T13263 26910-26916 NNP denotes Animal
T13264 26917-26921 NNP denotes Care
T13265 26922-26931 NNP denotes Committee
T13266 26932-26934 IN denotes of
T13267 26935-26943 NNP denotes Chungbuk
T13268 26944-26952 NNP denotes National
T13269 26953-26963 NNP denotes University
T13270 26963-26964 , denotes ,
T13271 26965-26970 NNP denotes Korea
T13272 26971-26972 -LRB- denotes (
T13273 26972-26989 NNP denotes CBNUA-045-0902-01
T13274 26989-26990 -RRB- denotes )
T13275 26990-26991 NNP denotes ]
T13276 26991-26992 . denotes .
T13591 26994-27001 NNS denotes Animals
T13592 27002-27005 DT denotes The
T13593 27006-27010 NNP denotes CCR5
T13594 27011-27015 JJ denotes wild
T13595 27016-27020 NN denotes type
T13596 27021-27022 -LRB- denotes (
T13597 27022-27026 CD denotes CCR5
T13598 27026-27027 CD denotes +
T13599 27027-27028 NN denotes /
T13600 27028-27029 NN denotes +
T13601 27029-27030 -RRB- denotes )
T13602 27031-27034 CC denotes and
T13603 27035-27039 CD denotes CCR5
T13604 27040-27048 NN denotes knockout
T13605 27049-27050 -LRB- denotes (
T13606 27050-27054 CD denotes CCR5
T13607 27054-27055 CD denotes −
T13608 27055-27056 NN denotes /
T13609 27056-27057 NN denotes −
T13610 27057-27058 -RRB- denotes )
T13611 27059-27063 NNS denotes mice
T13612 27064-27068 VBD denotes were
T13613 27069-27078 VBN denotes purchased
T13614 27079-27083 IN denotes from
T13615 27084-27087 DT denotes The
T13616 27088-27095 NNP denotes Jackson
T13617 27096-27106 NNP denotes Laboratory
T13618 27107-27108 -LRB- denotes (
T13619 27108-27111 NNP denotes Bar
T13620 27112-27118 NNP denotes Harbor
T13621 27118-27119 , denotes ,
T13622 27120-27125 NNP denotes Maine
T13623 27126-27131 CD denotes 04609
T13624 27132-27135 NNP denotes USA
T13625 27135-27136 -RRB- denotes )
T13626 27136-27137 . denotes .
T13627 27138-27141 DT denotes The
T13628 27142-27146 NNS denotes mice
T13629 27147-27151 VBD denotes were
T13630 27152-27158 VBN denotes housed
T13631 27159-27162 CC denotes and
T13632 27163-27167 VBN denotes bred
T13633 27168-27173 IN denotes under
T13634 27174-27182 JJ denotes specific
T13635 27183-27191 NN denotes pathogen
T13636 27192-27196 JJ denotes free
T13637 27197-27207 NNS denotes conditions
T13638 27208-27210 IN denotes at
T13639 27211-27214 DT denotes the
T13640 27215-27225 NNP denotes Laboratory
T13641 27226-27232 NNP denotes Animal
T13642 27233-27241 NNP denotes Research
T13643 27242-27248 NNP denotes Center
T13644 27249-27251 IN denotes of
T13645 27252-27260 NNP denotes Chungbuk
T13646 27261-27269 NNP denotes National
T13647 27270-27280 NNP denotes University
T13648 27280-27281 , denotes ,
T13649 27282-27287 NNP denotes Korea
T13650 27287-27288 . denotes .
T13651 27289-27292 DT denotes The
T13652 27293-27297 NNS denotes mice
T13653 27298-27299 -LRB- denotes (
T13654 27299-27300 FW denotes n
T13655 27301-27302 SYM denotes =
T13656 27303-27309 CD denotes 4/cage
T13657 27309-27310 -RRB- denotes )
T13658 27311-27315 VBD denotes were
T13659 27316-27326 VBN denotes maintained
T13660 27327-27329 IN denotes in
T13661 27330-27331 DT denotes a
T13662 27332-27336 NN denotes room
T13663 27337-27341 IN denotes with
T13664 27342-27343 DT denotes a
T13665 27344-27352 JJ denotes constant
T13666 27353-27364 NN denotes temperature
T13667 27365-27367 IN denotes of
T13668 27368-27370 CD denotes 22
T13669 27370-27371 NN denotes ±
T13670 27371-27372 CD denotes 1
T13671 27372-27373 CD denotes °
T13672 27373-27374 NNP denotes C
T13673 27374-27375 , denotes ,
T13674 27376-27384 JJ denotes relative
T13675 27385-27393 NN denotes humidity
T13676 27394-27396 IN denotes of
T13677 27397-27399 CD denotes 55
T13678 27399-27400 CD denotes ±
T13679 27400-27402 CD denotes 10
T13680 27402-27403 NN denotes %
T13681 27403-27404 , denotes ,
T13682 27405-27408 CC denotes and
T13683 27409-27413 JJ denotes 12-h
T13684 27414-27424 NN denotes light/dark
T13685 27425-27430 NN denotes cycle
T13686 27430-27431 , denotes ,
T13687 27432-27435 CC denotes and
T13688 27436-27439 VBN denotes fed
T13689 27440-27448 JJ denotes standard
T13690 27449-27455 NN denotes rodent
T13691 27456-27460 NN denotes chow
T13692 27461-27462 -LRB- denotes (
T13693 27462-27469 NNP denotes Samyang
T13694 27469-27470 , denotes ,
T13695 27471-27476 NNP denotes Korea
T13696 27476-27477 -RRB- denotes )
T13697 27478-27481 CC denotes and
T13698 27482-27490 VBN denotes purified
T13699 27491-27494 VBP denotes tap
T13700 27495-27500 NN denotes water
T13701 27501-27503 NN denotes ad
T13702 27504-27511 NN denotes libitum
T13703 27511-27512 . denotes .
T13704 27513-27516 DT denotes The
T13705 27517-27521 NNP denotes CCR5
T13706 27521-27522 NNP denotes +
T13707 27522-27523 VBD denotes /
T13708 27523-27524 CD denotes +
T13709 27525-27529 NNS denotes mice
T13710 27530-27531 -LRB- denotes (
T13711 27531-27532 FW denotes n
T13712 27533-27534 SYM denotes =
T13713 27535-27537 CD denotes 20
T13714 27537-27538 -RRB- denotes )
T13715 27539-27542 CC denotes and
T13716 27543-27547 CD denotes CCR5
T13717 27547-27548 CD denotes −
T13718 27548-27549 NN denotes /
T13719 27549-27550 NN denotes −
T13720 27551-27555 NNS denotes mice
T13721 27556-27557 -LRB- denotes (
T13722 27557-27558 FW denotes n
T13723 27559-27560 SYM denotes =
T13724 27561-27563 CD denotes 20
T13725 27563-27564 -RRB- denotes )
T13726 27564-27565 , denotes ,
T13727 27566-27570 WDT denotes that
T13728 27571-27575 VBD denotes were
T13729 27576-27580 VBN denotes used
T13730 27580-27581 , denotes ,
T13731 27582-27585 VBD denotes had
T13732 27586-27593 VBN denotes matched
T13733 27594-27598 NNS denotes ages
T13734 27599-27600 -LRB- denotes (
T13735 27600-27602 CD denotes 10
T13736 27603-27605 CD denotes 11
T13737 27606-27611 NNS denotes weeks
T13738 27612-27615 JJ denotes old
T13739 27615-27616 -RRB- denotes )
T13740 27617-27620 CC denotes and
T13741 27621-27628 NNS denotes weights
T13742 27629-27630 -LRB- denotes (
T13743 27630-27632 CD denotes 16
T13744 27633-27635 CD denotes 19
T13745 27636-27637 NN denotes g
T13746 27637-27638 -RRB- denotes )
T13747 27638-27639 . denotes .
T13748 27640-27647 NNP denotes Control
T13749 27648-27652 NNS denotes mice
T13750 27653-27654 -LRB- denotes (
T13751 27654-27664 CD denotes B6129PF2/J
T13752 27664-27665 -RRB- denotes )
T13753 27666-27670 VBD denotes were
T13754 27671-27673 CD denotes F2
T13755 27674-27680 JJ denotes hybrid
T13756 27681-27685 NNS denotes mice
T13757 27686-27690 IN denotes from
T13758 27691-27694 DT denotes the
T13759 27695-27708 NNP denotes C57BL/6J-AW-J
T13760 27709-27712 CC denotes and
T13761 27713-27720 NNP denotes 129P3/J
T13762 27721-27729 JJ denotes parental
T13763 27730-27737 NNS denotes strains
T13764 27737-27738 . denotes .
T13765 27739-27743 CD denotes CCR5
T13766 27744-27748 NNS denotes mice
T13767 27749-27750 -LRB- denotes (
T13768 27750-27752 CD denotes B6
T13769 27752-27753 , denotes ,
T13770 27754-27770 JJ denotes 129P2-Ccr5tm1Kuz
T13771 27770-27771 NN denotes /
T13772 27771-27772 NNP denotes J
T13773 27772-27773 -RRB- denotes )
T13774 27774-27778 VBP denotes have
T13775 27779-27782 DT denotes the
T13776 27783-27789 JJ denotes entire
T13777 27790-27796 NN denotes coding
T13778 27797-27803 NN denotes region
T13779 27804-27806 IN denotes of
T13780 27807-27810 DT denotes the
T13781 27811-27815 NNP denotes CCR5
T13782 27816-27820 NN denotes gene
T13783 27821-27828 VBD denotes deleted
T13784 27829-27833 IN denotes from
T13785 27834-27837 DT denotes the
T13786 27838-27846 JJ denotes parental
T13787 27847-27854 NNS denotes strains
T13788 27854-27855 , denotes ,
T13789 27856-27858 NNP denotes B6
T13790 27858-27859 : denotes ;
T13791 27859-27875 NNP denotes 129P2-Ccr5tm1kuz
T13792 27876-27879 CC denotes and
T13793 27880-27882 NNP denotes B6
T13794 27882-27883 : denotes ;
T13795 27883-27901 NNP denotes 129P2-Cmkbr5tm1Kuz
T13796 27901-27902 . denotes .
T13927 27904-27909 NNP denotes Tumor
T13928 27910-27921 NNP denotes Inoculation
T13929 27922-27925 CC denotes and
T13930 27926-27931 NNP denotes Tumor
T13931 27932-27942 NN denotes Monitoring
T13932 27943-27946 NNP denotes B16
T13933 27947-27955 NN denotes melanoma
T13934 27956-27961 NNS denotes cells
T13935 27962-27966 VBD denotes were
T13936 27967-27975 VBN denotes injected
T13937 27976-27990 RB denotes subcutaneously
T13938 27991-27992 JJ denotes [
T13939 27992-27993 CD denotes 5
T13940 27993-27994 CD denotes ×
T13941 27994-27997 CD denotes 105
T13942 27998-28003 NN denotes tumor
T13943 28004-28009 NNS denotes cells
T13944 28010-28012 IN denotes in
T13945 28013-28016 CD denotes 0.1
T13946 28017-28019 NN denotes ml
T13947 28020-28029 NNP denotes Phosphate
T13948 28030-28038 VBD denotes buffered
T13949 28039-28045 NN denotes saline
T13950 28045-28046 -LRB- denotes (
T13951 28046-28049 NNP denotes PBS
T13952 28049-28050 -RRB- denotes )
T13953 28050-28051 RB denotes /
T13954 28051-28057 JJ denotes animal
T13955 28057-28058 NNP denotes ]
T13956 28059-28064 VBG denotes using
T13957 28065-28066 DT denotes a
T13958 28067-28069 CD denotes 27
T13959 28070-28071 NNP denotes G
T13960 28072-28078 NN denotes needle
T13961 28079-28083 IN denotes into
T13962 28084-28087 DT denotes the
T13963 28088-28099 JJ denotes right-lower
T13964 28100-28106 NNS denotes flanks
T13965 28107-28109 IN denotes of
T13966 28110-28113 DT denotes the
T13967 28114-28121 NN denotes carrier
T13968 28122-28126 NNS denotes mice
T13969 28127-28129 IN denotes as
T13970 28130-28140 RB denotes previously
T13971 28141-28150 VBN denotes described
T13972 28151-28152 NNP denotes [
T13973 28152-28154 CD denotes 54
T13974 28154-28155 NNP denotes ]
T13975 28155-28156 . denotes .
T13976 28157-28160 DT denotes The
T13977 28161-28165 NN denotes body
T13978 28166-28173 NNS denotes weights
T13979 28174-28177 CC denotes and
T13980 28178-28183 NN denotes tumor
T13981 28184-28191 NNS denotes volumes
T13982 28192-28194 IN denotes of
T13983 28195-28198 DT denotes the
T13984 28199-28206 NNS denotes animals
T13985 28207-28211 VBD denotes were
T13986 28212-28221 VBN denotes monitored
T13987 28222-28227 RB denotes twice
T13988 28228-28234 JJ denotes weekly
T13989 28234-28235 . denotes .
T13990 28236-28239 DT denotes The
T13991 28240-28245 NN denotes tumor
T13992 28246-28253 NNS denotes volumes
T13993 28254-28258 VBD denotes were
T13994 28259-28267 VBN denotes measured
T13995 28268-28272 IN denotes with
T13996 28273-28280 NNP denotes Vernier
T13997 28281-28289 NNS denotes calipers
T13998 28290-28293 CC denotes and
T13999 28294-28304 VBN denotes calculated
T14000 28305-28310 VBG denotes using
T14001 28311-28314 DT denotes the
T14002 28315-28324 VBG denotes following
T14003 28325-28332 NN denotes formula
T14004 28332-28333 : denotes :
T14005 28334-28335 -LRB- denotes (
T14006 28335-28336 DT denotes A
T14007 28336-28337 NN denotes ×
T14008 28337-28339 NN denotes B2
T14009 28339-28340 -RRB- denotes )
T14010 28340-28341 NN denotes /
T14011 28341-28342 CD denotes 2
T14012 28342-28343 , denotes ,
T14013 28344-28349 WRB denotes where
T14014 28350-28351 DT denotes A
T14015 28352-28354 VBZ denotes is
T14016 28355-28358 DT denotes the
T14017 28359-28365 JJR denotes larger
T14018 28366-28369 CC denotes and
T14019 28370-28371 NNP denotes B
T14020 28372-28374 VBZ denotes is
T14021 28375-28378 DT denotes the
T14022 28379-28386 JJR denotes smaller
T14023 28387-28389 IN denotes of
T14024 28390-28393 DT denotes the
T14025 28394-28397 CD denotes two
T14026 28398-28408 NNS denotes dimensions
T14027 28408-28409 . denotes .
T14028 28410-28412 IN denotes At
T14029 28413-28416 DT denotes the
T14030 28417-28420 NN denotes end
T14031 28421-28423 IN denotes of
T14032 28424-28427 DT denotes the
T14033 28428-28438 NN denotes experiment
T14034 28438-28439 , denotes ,
T14035 28440-28443 DT denotes the
T14036 28444-28451 NNS denotes animals
T14037 28452-28456 VBD denotes were
T14038 28457-28467 VBN denotes sacrificed
T14039 28467-28468 . denotes .
T14040 28469-28472 DT denotes The
T14041 28473-28479 NNS denotes tumors
T14042 28480-28484 VBD denotes were
T14043 28485-28494 VBN denotes separated
T14044 28495-28499 IN denotes from
T14045 28500-28503 DT denotes the
T14046 28504-28515 VBG denotes surrounding
T14047 28516-28523 NNS denotes muscles
T14048 28524-28527 CC denotes and
T14049 28528-28534 NNS denotes dermis
T14050 28534-28535 . denotes .
T14406 28537-28544 JJ denotes Western
T14407 28545-28553 VBG denotes Blotting
T14408 28554-28559 NN denotes Tumor
T14409 28560-28567 NNS denotes tissues
T14410 28568-28572 VBD denotes were
T14411 28573-28584 VBN denotes homogenized
T14412 28585-28589 IN denotes with
T14413 28590-28597 NN denotes protein
T14414 28598-28608 NN denotes extraction
T14415 28609-28617 NN denotes solution
T14416 28618-28619 -LRB- denotes (
T14417 28619-28629 NNP denotes PRO-PREPTM
T14418 28629-28630 , denotes ,
T14419 28631-28637 NNP denotes Intron
T14420 28638-28651 NNP denotes Biotechnology
T14421 28651-28652 , denotes ,
T14422 28653-28658 NNP denotes Seoul
T14423 28658-28659 , denotes ,
T14424 28660-28665 NNP denotes Korea
T14425 28665-28666 -RRB- denotes )
T14426 28666-28667 , denotes ,
T14427 28668-28671 CC denotes and
T14428 28672-28677 VBN denotes lysed
T14429 28678-28680 IN denotes by
T14430 28681-28683 CD denotes 60
T14431 28684-28687 NN denotes min
T14432 28688-28698 NN denotes incubation
T14433 28699-28701 IN denotes on
T14434 28702-28705 NN denotes ice
T14435 28705-28706 . denotes .
T14436 28707-28710 DT denotes The
T14437 28711-28717 NN denotes tissue
T14438 28718-28724 NN denotes lysate
T14439 28725-28736 VBD denotes centrifuged
T14440 28737-28739 IN denotes at
T14441 28740-28746 CD denotes 15,000
T14442 28747-28750 NN denotes rpm
T14443 28751-28754 IN denotes for
T14444 28755-28757 CD denotes 15
T14445 28758-28761 NN denotes min
T14446 28762-28764 IN denotes at
T14447 28765-28766 CD denotes 4
T14448 28766-28767 CD denotes °
T14449 28767-28769 NNP denotes C.
T14450 28770-28775 NNP denotes Equal
T14451 28776-28783 NNS denotes amounts
T14452 28784-28786 IN denotes of
T14453 28787-28795 NNS denotes proteins
T14454 28796-28797 -LRB- denotes (
T14455 28797-28799 CD denotes 40
T14456 28800-28802 NN denotes µg
T14457 28802-28803 -RRB- denotes )
T14458 28804-28808 VBD denotes were
T14459 28809-28818 VBN denotes separated
T14460 28819-28821 IN denotes on
T14461 28822-28823 DT denotes a
T14462 28824-28830 CD denotes SDS/12
T14463 28830-28831 NN denotes %
T14464 28831-28832 : denotes -
T14465 28832-28846 NN denotes polyacrylamide
T14466 28847-28850 NN denotes gel
T14467 28850-28851 , denotes ,
T14468 28852-28855 CC denotes and
T14469 28856-28860 RB denotes then
T14470 28861-28872 VBD denotes transferred
T14471 28873-28875 TO denotes to
T14472 28876-28877 DT denotes a
T14473 28878-28892 NN denotes polyvinylidene
T14474 28893-28903 NN denotes difluoride
T14475 28904-28905 -LRB- denotes (
T14476 28905-28909 NNP denotes PVDF
T14477 28909-28910 -RRB- denotes )
T14478 28911-28919 NN denotes membrane
T14479 28920-28921 -LRB- denotes (
T14480 28921-28923 NNP denotes GE
T14481 28924-28929 NNP denotes Water
T14482 28930-28933 CC denotes and
T14483 28934-28941 NNP denotes Process
T14484 28942-28954 NNS denotes technologies
T14485 28954-28955 , denotes ,
T14486 28956-28963 NNP denotes Trevose
T14487 28963-28964 , denotes ,
T14488 28965-28967 NNP denotes PA
T14489 28967-28968 , denotes ,
T14490 28969-28972 NNP denotes USA
T14491 28972-28973 -RRB- denotes )
T14492 28973-28974 . denotes .
T14493 28975-28980 NNS denotes Blots
T14494 28981-28985 VBD denotes were
T14495 28986-28993 VBN denotes blocked
T14496 28994-28997 IN denotes for
T14497 28998-28999 CD denotes 1
T14498 29000-29001 NN denotes h
T14499 29002-29004 IN denotes at
T14500 29005-29009 NN denotes room
T14501 29010-29021 NN denotes temperature
T14502 29022-29026 IN denotes with
T14503 29027-29028 CD denotes 5
T14504 29028-29029 NN denotes %
T14505 29030-29031 -LRB- denotes (
T14506 29031-29034 FW denotes w/v
T14507 29034-29035 -RRB- denotes )
T14508 29036-29043 JJ denotes non-fat
T14509 29044-29049 VBN denotes dried
T14510 29050-29054 NN denotes milk
T14511 29055-29057 IN denotes in
T14512 29058-29071 NNP denotes Tris-Buffered
T14513 29072-29078 NNP denotes Saline
T14514 29079-29087 NNP denotes Tween-20
T14515 29088-29089 NNP denotes [
T14516 29089-29093 NNP denotes TBST
T14517 29093-29094 : denotes :
T14518 29095-29097 CD denotes 10
T14519 29098-29100 NNP denotes mM
T14520 29101-29105 NNP denotes Tris
T14521 29106-29107 -LRB- denotes (
T14522 29107-29109 NNP denotes pH
T14523 29110-29113 CD denotes 8.0
T14524 29113-29114 -RRB- denotes )
T14525 29115-29118 CC denotes and
T14526 29119-29122 CD denotes 150
T14527 29123-29125 NNP denotes mM
T14528 29126-29130 NNP denotes NaCl
T14529 29131-29139 NN denotes solution
T14530 29140-29150 VBG denotes containing
T14531 29151-29155 CD denotes 0.05
T14532 29155-29156 NN denotes %
T14533 29157-29165 CD denotes Tween-20
T14534 29165-29166 NNP denotes ]
T14535 29166-29167 . denotes .
T14536 29168-29173 IN denotes After
T14537 29174-29175 DT denotes a
T14538 29176-29181 JJ denotes short
T14539 29182-29189 VBG denotes washing
T14540 29190-29192 IN denotes in
T14541 29193-29197 NNP denotes TBST
T14542 29197-29198 , denotes ,
T14543 29199-29202 DT denotes the
T14544 29203-29212 NNS denotes membranes
T14545 29213-29217 VBD denotes were
T14546 29218-29231 VBN denotes immunoblotted
T14547 29232-29236 IN denotes with
T14548 29237-29240 DT denotes the
T14549 29241-29250 VBG denotes following
T14550 29251-29258 JJ denotes primary
T14551 29259-29269 NNS denotes antibodies
T14552 29269-29270 : denotes :
T14553 29271-29276 NN denotes mouse
T14554 29277-29287 JJ denotes monoclonal
T14555 29288-29298 NNS denotes antibodies
T14556 29299-29307 VBN denotes directed
T14557 29308-29315 IN denotes against
T14558 29316-29319 CD denotes p65
T14559 29320-29323 CC denotes and
T14560 29324-29327 CD denotes p50
T14561 29328-29329 -LRB- denotes (
T14562 29329-29330 CD denotes 1
T14563 29330-29331 CD denotes ∶
T14564 29331-29334 CD denotes 500
T14565 29335-29344 NNS denotes dilutions
T14566 29344-29345 : denotes ;
T14567 29346-29351 NNP denotes Santa
T14568 29352-29356 NNP denotes Cruz
T14569 29357-29370 NNP denotes Biotechnology
T14570 29370-29371 , denotes ,
T14571 29372-29377 NNP denotes Santa
T14572 29378-29382 NNP denotes Cruz
T14573 29382-29383 , denotes ,
T14574 29384-29386 NNP denotes CA
T14575 29386-29387 -RRB- denotes )
T14576 29387-29388 , denotes ,
T14577 29389-29395 NN denotes rabbit
T14578 29396-29406 NN denotes polyclonal
T14579 29407-29417 NNS denotes antibodies
T14580 29418-29426 VBN denotes directed
T14581 29427-29434 IN denotes against
T14582 29435-29438 NNP denotes Bax
T14583 29439-29442 CC denotes and
T14584 29443-29447 NNP denotes PARP
T14585 29448-29449 -LRB- denotes (
T14586 29449-29450 CD denotes 1
T14587 29450-29451 CD denotes ∶
T14588 29451-29454 CD denotes 500
T14589 29455-29464 NNS denotes dilutions
T14590 29464-29465 : denotes ;
T14591 29466-29471 NNP denotes Santa
T14592 29472-29476 NNP denotes Cruz
T14593 29477-29490 NNP denotes Biotechnology
T14594 29490-29491 -RRB- denotes )
T14595 29491-29492 , denotes ,
T14596 29493-29496 CC denotes and
T14597 29497-29504 IN denotes against
T14598 29505-29514 JJ denotes caspase-3
T14599 29514-29515 , denotes ,
T14600 29516-29525 JJ denotes caspase-9
T14601 29525-29526 , denotes ,
T14602 29527-29532 JJ denotes Bcl-2
T14603 29533-29536 CC denotes and
T14604 29537-29544 JJ denotes c-IAP-1
T14605 29545-29546 -LRB- denotes (
T14606 29546-29547 CD denotes 1
T14607 29547-29548 CD denotes ∶
T14608 29548-29552 CD denotes 1000
T14609 29553-29562 NNS denotes dilutions
T14610 29562-29563 : denotes ;
T14611 29564-29568 NNP denotes Cell
T14612 29569-29578 NNP denotes Signaling
T14613 29579-29589 NNP denotes Technology
T14614 29589-29590 , denotes ,
T14615 29591-29598 NNP denotes Beverly
T14616 29598-29599 , denotes ,
T14617 29600-29602 NNP denotes MA
T14618 29602-29603 -RRB- denotes )
T14619 29603-29604 . denotes .
T14620 29605-29608 DT denotes The
T14621 29609-29614 NNS denotes blots
T14622 29615-29619 VBD denotes were
T14623 29620-29629 VBN denotes incubated
T14624 29630-29634 IN denotes with
T14625 29635-29638 DT denotes the
T14626 29639-29649 JJ denotes respective
T14627 29650-29661 JJ denotes horseradish
T14628 29662-29683 JJ denotes peroxidase-conjugated
T14629 29684-29695 JJ denotes anti-rabbit
T14630 29696-29698 CC denotes or
T14631 29699-29709 JJ denotes anti-mouse
T14632 29710-29713 NNP denotes IgG
T14633 29714-29715 -LRB- denotes (
T14634 29715-29716 CD denotes 1
T14635 29716-29717 CD denotes ∶
T14636 29717-29721 CD denotes 4000
T14637 29722-29731 NNS denotes dilutions
T14638 29731-29732 : denotes ;
T14639 29733-29738 NNP denotes Santa
T14640 29739-29743 NNP denotes Cruz
T14641 29744-29757 NNP denotes Biotechnology
T14642 29757-29758 -RRB- denotes )
T14643 29758-29759 . denotes .
T14644 29760-29774 JJ denotes Immunoreactive
T14645 29775-29783 NNS denotes proteins
T14646 29784-29788 VBD denotes were
T14647 29789-29797 VBN denotes detected
T14648 29798-29802 IN denotes with
T14649 29803-29806 DT denotes the
T14650 29807-29810 NNP denotes ECL
T14651 29811-29820 NN denotes detection
T14652 29821-29827 NN denotes system
T14653 29827-29828 . denotes .
T15029 29830-29850 NNP denotes Immunohistochemistry
T15030 29851-29854 NNP denotes All
T15031 29855-29864 NNS denotes specimens
T15032 29865-29869 VBD denotes were
T15033 29870-29875 VBN denotes fixed
T15034 29876-29878 IN denotes in
T15035 29879-29887 NN denotes formalin
T15036 29888-29891 CC denotes and
T15037 29892-29900 VBN denotes embedded
T15038 29901-29903 IN denotes in
T15039 29904-29912 NN denotes paraffin
T15040 29913-29916 IN denotes for
T15041 29917-29928 NN denotes examination
T15042 29928-29929 . denotes .
T15043 29930-29938 NNS denotes Sections
T15044 29939-29940 -LRB- denotes (
T15045 29940-29941 CD denotes 4
T15046 29942-29944 NN denotes µm
T15047 29945-29950 JJ denotes thick
T15048 29950-29951 -RRB- denotes )
T15049 29952-29956 VBD denotes were
T15050 29957-29964 VBN denotes stained
T15051 29965-29969 IN denotes with
T15052 29970-29973 NNP denotes H&E
T15053 29974-29977 CC denotes and
T15054 29978-29986 VBN denotes analyzed
T15055 29987-29989 IN denotes by
T15056 29990-30010 NN denotes immunohistochemistry
T15057 30010-30011 . denotes .
T15058 30012-30015 DT denotes The
T15059 30016-30033 JJ denotes paraffin-embedded
T15060 30034-30042 NNS denotes sections
T15061 30043-30047 VBD denotes were
T15062 30048-30062 VBN denotes deparaffinized
T15063 30063-30066 CC denotes and
T15064 30067-30077 VBN denotes rehydrated
T15065 30077-30078 , denotes ,
T15066 30079-30085 VBN denotes washed
T15067 30086-30088 IN denotes in
T15068 30089-30098 JJ denotes distilled
T15069 30099-30104 NN denotes water
T15070 30104-30105 , denotes ,
T15071 30106-30109 CC denotes and
T15072 30110-30114 RB denotes then
T15073 30115-30124 VBN denotes subjected
T15074 30125-30127 TO denotes to
T15075 30128-30141 JJ denotes heat-mediated
T15076 30142-30149 NN denotes antigen
T15077 30150-30159 NN denotes retrieval
T15078 30159-30160 . denotes .
T15079 30161-30171 JJ denotes Endogenous
T15080 30172-30182 NN denotes peroxidase
T15081 30183-30191 NN denotes activity
T15082 30192-30195 VBD denotes was
T15083 30196-30204 VBN denotes quenched
T15084 30205-30207 IN denotes by
T15085 30208-30218 NN denotes incubation
T15086 30219-30221 IN denotes in
T15087 30222-30223 CD denotes 3
T15088 30223-30224 NN denotes %
T15089 30225-30233 NN denotes hydrogen
T15090 30234-30242 NN denotes peroxide
T15091 30243-30245 IN denotes in
T15092 30246-30254 NN denotes methanol
T15093 30255-30258 IN denotes for
T15094 30259-30261 CD denotes 15
T15095 30262-30265 NN denotes min
T15096 30265-30266 , denotes ,
T15097 30267-30275 VBN denotes followed
T15098 30276-30278 IN denotes by
T15099 30279-30287 VBG denotes clearing
T15100 30288-30290 IN denotes in
T15101 30291-30294 NNP denotes PBS
T15102 30295-30298 IN denotes for
T15103 30299-30300 CD denotes 5
T15104 30301-30304 NN denotes min
T15105 30304-30305 . denotes .
T15106 30306-30309 DT denotes The
T15107 30310-30318 NNS denotes sections
T15108 30319-30323 VBD denotes were
T15109 30324-30331 VBN denotes blocked
T15110 30332-30335 IN denotes for
T15111 30336-30338 CD denotes 30
T15112 30339-30342 NN denotes min
T15113 30343-30347 IN denotes with
T15114 30348-30349 CD denotes 3
T15115 30349-30350 NN denotes %
T15116 30351-30357 JJ denotes normal
T15117 30358-30363 NN denotes horse
T15118 30364-30369 NN denotes serum
T15119 30370-30377 VBN denotes diluted
T15120 30378-30380 IN denotes in
T15121 30381-30384 NNP denotes PBS
T15122 30384-30385 , denotes ,
T15123 30386-30393 VBD denotes blotted
T15124 30393-30394 , denotes ,
T15125 30395-30398 CC denotes and
T15126 30399-30408 VBN denotes incubated
T15127 30409-30413 IN denotes with
T15128 30414-30421 JJ denotes primary
T15129 30422-30427 NN denotes mouse
T15130 30428-30438 JJ denotes anti-mouse
T15131 30439-30452 VBG denotes proliferating
T15132 30453-30457 NN denotes cell
T15133 30458-30465 JJ denotes nuclear
T15134 30466-30473 NN denotes antigen
T15135 30474-30475 -LRB- denotes (
T15136 30475-30479 NNP denotes PCNA
T15137 30479-30480 , denotes ,
T15138 30481-30482 CD denotes 1
T15139 30482-30483 CD denotes ∶
T15140 30483-30486 CD denotes 200
T15141 30487-30495 NN denotes dilution
T15142 30495-30496 -RRB- denotes )
T15143 30497-30507 JJ denotes monoclonal
T15144 30508-30518 NNS denotes antibodies
T15145 30519-30521 IN denotes in
T15146 30522-30530 VBG denotes blocking
T15147 30531-30536 NN denotes serum
T15148 30537-30540 IN denotes for
T15149 30541-30542 CD denotes 4
T15150 30543-30544 NN denotes h
T15151 30545-30547 IN denotes at
T15152 30548-30552 NN denotes room
T15153 30553-30564 NN denotes temperature
T15154 30564-30565 . denotes .
T15155 30566-30576 RB denotes Thereafter
T15156 30576-30577 , denotes ,
T15157 30578-30581 DT denotes the
T15158 30582-30588 NNS denotes slides
T15159 30589-30593 VBD denotes were
T15160 30594-30600 VBN denotes washed
T15161 30601-30606 CD denotes three
T15162 30607-30612 NNS denotes times
T15163 30613-30616 IN denotes for
T15164 30617-30618 CD denotes 5
T15165 30619-30622 NN denotes min
T15166 30623-30627 DT denotes each
T15167 30628-30630 IN denotes in
T15168 30631-30634 NNP denotes PBS
T15169 30635-30638 CC denotes and
T15170 30639-30648 VBN denotes incubated
T15171 30649-30653 IN denotes with
T15172 30654-30666 JJ denotes biotinylated
T15173 30667-30677 NN denotes anti-mouse
T15174 30678-30681 CC denotes and
T15175 30682-30693 JJ denotes anti-rabbit
T15176 30694-30704 NNS denotes antibodies
T15177 30705-30708 IN denotes for
T15178 30709-30710 CD denotes 2
T15179 30711-30712 NN denotes h
T15180 30712-30713 . denotes .
T15181 30714-30717 DT denotes The
T15182 30718-30724 NNS denotes slides
T15183 30725-30729 VBD denotes were
T15184 30730-30736 VBN denotes washed
T15185 30737-30739 IN denotes in
T15186 30740-30743 NNP denotes PBS
T15187 30743-30744 , denotes ,
T15188 30745-30753 VBN denotes followed
T15189 30754-30756 IN denotes by
T15190 30757-30760 DT denotes the
T15191 30761-30769 NN denotes addition
T15192 30770-30772 IN denotes of
T15193 30773-30776 DT denotes the
T15194 30777-30783 NN denotes avidin
T15195 30784-30790 NN denotes biotin
T15196 30791-30801 NN denotes peroxidase
T15197 30802-30809 NN denotes complex
T15198 30810-30811 -LRB- denotes (
T15199 30811-30814 NNP denotes ABC
T15200 30815-30818 NN denotes kit
T15201 30818-30819 : denotes ;
T15202 30820-30826 NNP denotes Vector
T15203 30827-30839 NNPS denotes Laboratories
T15204 30839-30840 , denotes ,
T15205 30841-30851 NNP denotes Burlingame
T15206 30851-30852 , denotes ,
T15207 30853-30855 NNP denotes CA
T15208 30855-30856 , denotes ,
T15209 30857-30860 NNP denotes USA
T15210 30860-30861 -RRB- denotes )
T15211 30861-30862 . denotes .
T15212 30863-30866 DT denotes The
T15213 30867-30873 NNS denotes slides
T15214 30874-30878 VBD denotes were
T15215 30879-30885 VBN denotes washed
T15216 30886-30889 CC denotes and
T15217 30890-30893 DT denotes the
T15218 30894-30904 JJ denotes peroxidase
T15219 30905-30913 NN denotes reaction
T15220 30914-30917 VBD denotes was
T15221 30918-30927 VBN denotes developed
T15222 30928-30932 IN denotes with
T15223 30933-30949 NN denotes diaminobenzidine
T15224 30950-30951 -LRB- denotes (
T15225 30951-30954 NNP denotes DAB
T15226 30954-30955 -RRB- denotes )
T15227 30956-30959 CC denotes and
T15228 30960-30968 NN denotes peroxide
T15229 30968-30969 , denotes ,
T15230 30970-30978 VBN denotes followed
T15231 30979-30981 IN denotes by
T15232 30982-30997 VBG denotes counterstaining
T15233 30998-31002 IN denotes with
T15234 31003-31014 NN denotes hematoxylin
T15235 31014-31015 , denotes ,
T15236 31016-31024 VBG denotes mounting
T15237 31025-31027 IN denotes in
T15238 31028-31038 JJ denotes aqua-mount
T15239 31038-31039 , denotes ,
T15240 31040-31043 CC denotes and
T15241 31044-31054 NN denotes evaluation
T15242 31055-31060 IN denotes under
T15243 31061-31062 DT denotes a
T15244 31063-31068 JJ denotes light
T15245 31069-31079 NN denotes microscope
T15246 31080-31081 -LRB- denotes (
T15247 31081-31094 NN denotes magnification
T15248 31094-31095 RB denotes ×
T15249 31095-31098 CD denotes 200
T15250 31098-31099 : denotes ;
T15251 31100-31107 NNP denotes Olympus
T15252 31107-31108 , denotes ,
T15253 31109-31114 NNP denotes Tokyo
T15254 31114-31115 , denotes ,
T15255 31116-31121 NNP denotes Japan
T15256 31121-31122 -RRB- denotes )
T15257 31122-31123 . denotes .
T15258 31124-31125 DT denotes A
T15259 31126-31134 JJ denotes negative
T15260 31135-31142 NN denotes control
T15261 31143-31146 VBD denotes was
T15262 31147-31155 VBN denotes included
T15263 31156-31158 IN denotes in
T15264 31159-31162 DT denotes all
T15265 31163-31174 NNS denotes experiments
T15266 31175-31177 IN denotes by
T15267 31178-31186 VBG denotes omitting
T15268 31187-31190 DT denotes the
T15269 31191-31198 JJ denotes primary
T15270 31199-31207 NN denotes antibody
T15271 31207-31208 . denotes .
T15272 31209-31212 IN denotes For
T15273 31213-31216 DT denotes the
T15274 31217-31226 NN denotes detection
T15275 31227-31229 IN denotes of
T15276 31230-31239 JJ denotes apoptotic
T15277 31240-31244 NN denotes cell
T15278 31245-31250 NN denotes death
T15279 31251-31253 IN denotes in
T15280 31254-31257 DT denotes the
T15281 31258-31263 NN denotes tumor
T15282 31264-31271 NNS denotes tissues
T15283 31271-31272 , denotes ,
T15284 31273-31276 DT denotes the
T15285 31277-31294 JJ denotes paraffin-embedded
T15286 31295-31303 NNS denotes sections
T15287 31304-31308 VBD denotes were
T15288 31309-31318 VBN denotes incubated
T15289 31319-31321 IN denotes in
T15290 31322-31323 DT denotes a
T15291 31324-31331 NN denotes mixture
T15292 31332-31334 IN denotes of
T15293 31335-31338 DT denotes the
T15294 31339-31347 VBG denotes labeling
T15295 31348-31356 NN denotes solution
T15296 31357-31358 -LRB- denotes (
T15297 31358-31361 CD denotes 540
T15298 31362-31364 NN denotes µl
T15299 31364-31365 -RRB- denotes )
T15300 31366-31369 CC denotes and
T15301 31370-31376 VB denotes enzyme
T15302 31377-31385 NN denotes solution
T15303 31386-31387 -LRB- denotes (
T15304 31387-31389 CD denotes 60
T15305 31390-31392 NN denotes µl
T15306 31392-31393 -RRB- denotes )
T15307 31394-31397 IN denotes for
T15308 31398-31399 CD denotes 1
T15309 31400-31401 NN denotes h
T15310 31402-31404 IN denotes at
T15311 31405-31407 CD denotes 37
T15312 31407-31408 CD denotes °
T15313 31408-31409 NNP denotes C
T15314 31409-31410 , denotes ,
T15315 31411-31414 CC denotes and
T15316 31415-31419 RB denotes then
T15317 31420-31426 VBD denotes washed
T15318 31427-31432 CD denotes three
T15319 31433-31438 NNS denotes times
T15320 31439-31441 IN denotes in
T15321 31442-31445 CD denotes 0.1
T15322 31446-31447 NNP denotes M
T15323 31448-31451 NNP denotes PBS
T15324 31452-31455 IN denotes for
T15325 31456-31457 CD denotes 5
T15326 31458-31461 NN denotes min
T15327 31462-31466 DT denotes each
T15328 31466-31467 , denotes ,
T15329 31468-31477 VBG denotes according
T15330 31478-31480 TO denotes to
T15331 31481-31484 DT denotes the
T15332 31485-31497 NN denotes manufacturer
T15333 31500-31512 NNS denotes instructions
T15334 31512-31513 . denotes .
T15335 31514-31518 JJ denotes Next
T15336 31518-31519 , denotes ,
T15337 31520-31523 DT denotes the
T15338 31524-31532 NNS denotes sections
T15339 31533-31537 VBD denotes were
T15340 31538-31547 VBN denotes incubated
T15341 31548-31552 IN denotes with
T15342 31553-31554 CD denotes 4
T15343 31554-31555 CD denotes ′
T15344 31555-31557 SYM denotes ,6
T15345 31557-31558 : denotes -
T15346 31558-31582 NN denotes diamidino-2-phenylindole
T15347 31583-31584 -LRB- denotes (
T15348 31584-31588 NNP denotes DAPI
T15349 31588-31589 -RRB- denotes )
T15350 31590-31593 IN denotes for
T15351 31594-31596 CD denotes 15
T15352 31597-31600 NN denotes min
T15353 31601-31603 IN denotes at
T15354 31604-31606 CD denotes 37
T15355 31606-31607 CD denotes °
T15356 31607-31609 NNP denotes C.
T15357 31610-31617 RB denotes Finally
T15358 31617-31618 , denotes ,
T15359 31619-31622 DT denotes the
T15360 31623-31631 NNS denotes sections
T15361 31632-31636 VBD denotes were
T15362 31637-31643 VBN denotes rinsed
T15363 31643-31644 , denotes ,
T15364 31645-31652 VBN denotes mounted
T15365 31653-31655 IN denotes on
T15366 31656-31662 NNS denotes slides
T15367 31662-31663 , denotes ,
T15368 31664-31667 CC denotes and
T15369 31668-31681 JJ denotes cover-slipped
T15370 31682-31685 IN denotes for
T15371 31686-31698 NN denotes fluorescence
T15372 31699-31709 NN denotes microscopy
T15373 31710-31711 -LRB- denotes (
T15374 31711-31714 NNP denotes DAS
T15375 31715-31725 NN denotes microscope
T15376 31725-31726 -RRB- denotes )
T15377 31726-31727 . denotes .
T15506 31729-31747 NNP denotes Immunofluorescence
T15507 31748-31756 NNS denotes Sections
T15508 31757-31761 VBD denotes were
T15509 31762-31769 VBN denotes treated
T15510 31770-31774 IN denotes with
T15511 31775-31777 CD denotes 10
T15512 31777-31778 NN denotes %
T15513 31779-31785 JJ denotes bovine
T15514 31786-31791 NN denotes serum
T15515 31792-31799 NN denotes albumin
T15516 31800-31802 IN denotes in
T15517 31803-31806 NNP denotes PBS
T15518 31807-31810 IN denotes for
T15519 31811-31812 CD denotes 1
T15520 31813-31814 NN denotes h
T15521 31815-31817 IN denotes at
T15522 31818-31822 NN denotes room
T15523 31823-31834 NN denotes temperature
T15524 31834-31835 , denotes ,
T15525 31836-31845 JJ denotes incubated
T15526 31846-31855 JJ denotes overnight
T15527 31856-31858 IN denotes at
T15528 31859-31860 CD denotes 4
T15529 31860-31861 CD denotes °
T15530 31861-31862 NNP denotes C
T15531 31863-31867 IN denotes with
T15532 31868-31871 CD denotes p50
T15533 31872-31873 -LRB- denotes (
T15534 31873-31874 CD denotes 1
T15535 31874-31875 CD denotes ∶
T15536 31875-31878 CD denotes 250
T15537 31878-31879 , denotes ,
T15538 31880-31885 NNP denotes Santa
T15539 31886-31890 NNP denotes Cruz
T15540 31891-31904 NNP denotes Biotechnology
T15541 31904-31905 , denotes ,
T15542 31906-31911 NNP denotes Santa
T15543 31912-31916 NNP denotes Cruz
T15544 31916-31917 , denotes ,
T15545 31918-31920 NNP denotes CA
T15546 31920-31921 -RRB- denotes )
T15547 31921-31922 , denotes ,
T15548 31923-31926 NNS denotes p65
T15549 31927-31928 -LRB- denotes (
T15550 31928-31929 CD denotes 1
T15551 31929-31930 CD denotes ∶
T15552 31930-31933 CD denotes 250
T15553 31933-31934 , denotes ,
T15554 31935-31940 NNP denotes Santa
T15555 31941-31945 NNP denotes Cruz
T15556 31946-31959 NNP denotes Biotechnology
T15557 31959-31960 , denotes ,
T15558 31961-31966 NNP denotes Santa
T15559 31967-31971 NNP denotes Cruz
T15560 31971-31972 , denotes ,
T15561 31973-31975 NNP denotes CA
T15562 31975-31976 -RRB- denotes )
T15563 31976-31977 , denotes ,
T15564 31978-31981 NNP denotes Bax
T15565 31982-31983 -LRB- denotes (
T15566 31983-31984 CD denotes 1
T15567 31984-31985 CD denotes ∶
T15568 31985-31988 CD denotes 200
T15569 31989-31997 NN denotes dilution
T15570 31997-31998 -RRB- denotes )
T15571 31998-31999 , denotes ,
T15572 32000-32007 VBN denotes cleaved
T15573 32008-32017 JJ denotes caspase-3
T15574 32018-32019 -LRB- denotes (
T15575 32019-32020 CD denotes 1
T15576 32020-32021 CD denotes ∶
T15577 32021-32024 CD denotes 100
T15578 32024-32025 -RRB- denotes )
T15579 32025-32026 , denotes ,
T15580 32027-32030 NNP denotes CD8
T15581 32031-32032 -LRB- denotes (
T15582 32032-32033 CD denotes 1
T15583 32033-32034 CD denotes ∶
T15584 32034-32036 CD denotes 10
T15585 32036-32037 -RRB- denotes )
T15586 32037-32038 , denotes ,
T15587 32039-32043 NNP denotes CD57
T15588 32044-32045 -LRB- denotes (
T15589 32045-32046 CD denotes 1
T15590 32046-32047 CD denotes ∶
T15591 32047-32049 CD denotes 50
T15592 32049-32050 -RRB- denotes )
T15593 32051-32054 CC denotes and
T15594 32055-32061 NNP denotes IL-1Ra
T15595 32062-32063 -LRB- denotes (
T15596 32063-32064 CD denotes 1
T15597 32064-32065 CD denotes ∶
T15598 32065-32068 CD denotes 500
T15599 32068-32069 -RRB- denotes )
T15600 32070-32080 NNS denotes antibodies
T15601 32080-32081 , denotes ,
T15602 32082-32090 VBN denotes followed
T15603 32091-32093 IN denotes by
T15604 32094-32104 NN denotes incubation
T15605 32105-32107 IN denotes in
T15606 32108-32118 JJ denotes anti-mouse
T15607 32119-32122 NNP denotes IgG
T15608 32123-32133 VBN denotes conjugated
T15609 32134-32138 IN denotes with
T15610 32139-32144 NNP denotes Alexa
T15611 32145-32148 CD denotes 488
T15612 32149-32150 -LRB- denotes (
T15613 32150-32151 CD denotes 1
T15614 32151-32152 CD denotes ∶
T15615 32152-32155 CD denotes 100
T15616 32156-32164 NN denotes dilution
T15617 32164-32165 , denotes ,
T15618 32166-32175 NNP denotes Molecular
T15619 32176-32182 NNP denotes Probes
T15620 32182-32183 , denotes ,
T15621 32184-32190 NNP denotes Eugene
T15622 32190-32191 , denotes ,
T15623 32192-32194 NNP denotes OR
T15624 32194-32195 , denotes ,
T15625 32196-32199 NNP denotes USA
T15626 32199-32200 -RRB- denotes )
T15627 32201-32204 CC denotes and
T15628 32205-32216 JJ denotes anti-rabbit
T15629 32217-32220 NNP denotes IgG
T15630 32221-32231 VBN denotes conjugated
T15631 32232-32236 IN denotes with
T15632 32237-32242 NNP denotes Alexa
T15633 32243-32246 CD denotes 568
T15634 32247-32248 -LRB- denotes (
T15635 32248-32249 CD denotes 1
T15636 32249-32250 CD denotes ∶
T15637 32250-32253 CD denotes 100
T15638 32254-32262 NN denotes dilution
T15639 32262-32263 , denotes ,
T15640 32264-32273 NNP denotes Molecular
T15641 32274-32280 NNP denotes Probes
T15642 32280-32281 -RRB- denotes )
T15643 32282-32285 IN denotes for
T15644 32286-32288 CD denotes 40
T15645 32289-32292 NN denotes min
T15646 32293-32295 IN denotes at
T15647 32296-32300 NN denotes room
T15648 32301-32312 NN denotes temperature
T15649 32312-32313 . denotes .
T15650 32314-32321 RB denotes Finally
T15651 32321-32322 , denotes ,
T15652 32323-32326 DT denotes the
T15653 32327-32335 NNS denotes sections
T15654 32336-32340 VBD denotes were
T15655 32341-32347 VBN denotes rinsed
T15656 32347-32348 , denotes ,
T15657 32349-32356 VBN denotes mounted
T15658 32357-32359 IN denotes on
T15659 32360-32366 NNS denotes slides
T15660 32366-32367 , denotes ,
T15661 32368-32371 CC denotes and
T15662 32372-32385 JJ denotes cover-slipped
T15663 32386-32389 IN denotes for
T15664 32390-32402 NN denotes fluorescence
T15665 32403-32413 NN denotes microscopy
T15666 32414-32417 CC denotes and
T15667 32418-32429 NN denotes photography
T15668 32430-32435 VBG denotes using
T15669 32436-32443 NNP denotes ApoTome
T15670 32444-32454 NN denotes microscopy
T15671 32455-32456 -LRB- denotes (
T15672 32456-32460 NNP denotes Carl
T15673 32461-32466 NNP denotes Zeiss
T15674 32466-32467 , denotes ,
T15675 32468-32477 NNP denotes Thornwood
T15676 32477-32478 , denotes ,
T15677 32479-32481 NNP denotes NY
T15678 32481-32482 , denotes ,
T15679 32483-32486 NNP denotes USA
T15680 32486-32487 -RRB- denotes )
T15681 32487-32488 . denotes .
T15919 32490-32493 NNP denotes Gel
T15920 32494-32509 NNP denotes Electromobility
T15921 32510-32515 NNP denotes Shift
T15922 32516-32521 NNP denotes Assay
T15923 32522-32523 NNP denotes A
T15924 32524-32527 NN denotes gel
T15925 32528-32543 NN denotes electromobility
T15926 32544-32549 NN denotes shift
T15927 32550-32555 NN denotes assay
T15928 32556-32557 -LRB- denotes (
T15929 32557-32561 NNP denotes EMSA
T15930 32561-32562 -RRB- denotes )
T15931 32563-32566 VBD denotes was
T15932 32567-32576 VBN denotes performed
T15933 32577-32586 VBG denotes according
T15934 32587-32589 TO denotes to
T15935 32590-32593 DT denotes the
T15936 32594-32606 NN denotes manufacturer
T15937 32609-32624 NNS denotes recommendations
T15938 32625-32626 -LRB- denotes (
T15939 32626-32633 NNP denotes Promega
T15940 32633-32634 , denotes ,
T15941 32635-32642 NNP denotes Madison
T15942 32642-32643 , denotes ,
T15943 32644-32646 NNP denotes WI
T15944 32646-32647 -RRB- denotes )
T15945 32647-32648 . denotes .
T15946 32649-32652 DT denotes The
T15947 32653-32658 NN denotes tumor
T15948 32659-32666 NNS denotes tissues
T15949 32667-32671 VBD denotes were
T15950 32672-32679 RB denotes briefly
T15951 32680-32691 VBN denotes homogenized
T15952 32692-32694 IN denotes in
T15953 32695-32698 CD denotes 200
T15954 32699-32701 NN denotes µl
T15955 32702-32704 IN denotes of
T15956 32705-32713 NN denotes solution
T15957 32714-32715 DT denotes A
T15958 32716-32717 -LRB- denotes (
T15959 32717-32719 CD denotes 10
T15960 32720-32722 NNP denotes mM
T15961 32723-32728 NNP denotes HEPES
T15962 32729-32730 NNP denotes [
T15963 32730-32732 NNP denotes pH
T15964 32733-32736 CD denotes 7.9
T15965 32736-32737 NNP denotes ]
T15966 32737-32738 , denotes ,
T15967 32739-32742 CD denotes 1.5
T15968 32743-32745 NNP denotes mM
T15969 32746-32751 NNP denotes MgCl2
T15970 32751-32752 , denotes ,
T15971 32753-32755 CD denotes 10
T15972 32756-32758 NNP denotes mM
T15973 32759-32762 NNP denotes KCl
T15974 32762-32763 , denotes ,
T15975 32764-32767 CD denotes 0.5
T15976 32768-32770 NNP denotes mM
T15977 32771-32785 NN denotes dithiothreitol
T15978 32785-32786 , denotes ,
T15979 32787-32790 CD denotes 0.2
T15980 32791-32793 NNP denotes mM
T15981 32794-32822 NN denotes phenylmethylsulfonylfluoride
T15982 32822-32823 -RRB- denotes )
T15983 32823-32824 , denotes ,
T15984 32825-32833 JJ denotes vortexed
T15985 32834-32844 RB denotes vigorously
T15986 32844-32845 , denotes ,
T15987 32846-32855 VBN denotes incubated
T15988 32856-32858 IN denotes on
T15989 32859-32862 NN denotes ice
T15990 32863-32866 IN denotes for
T15991 32867-32869 CD denotes 10
T15992 32870-32873 NN denotes min
T15993 32873-32874 , denotes ,
T15994 32875-32878 CC denotes and
T15995 32879-32883 RB denotes then
T15996 32884-32895 VBD denotes centrifuged
T15997 32896-32898 IN denotes at
T15998 32899-32904 CD denotes 15000
T15999 32905-32908 NN denotes rpm
T16000 32909-32912 IN denotes for
T16001 32913-32915 CD denotes 15
T16002 32916-32919 NN denotes min
T16003 32919-32920 . denotes .
T16004 32921-32924 DT denotes The
T16005 32925-32933 JJ denotes pelleted
T16006 32934-32940 NNS denotes nuclei
T16007 32941-32945 VBD denotes were
T16008 32946-32957 VBN denotes resuspended
T16009 32958-32960 IN denotes in
T16010 32961-32969 NN denotes solution
T16011 32970-32971 NNP denotes C
T16012 32972-32973 -LRB- denotes (
T16013 32973-32981 NN denotes solution
T16014 32982-32983 DT denotes A
T16015 32984-32996 VBN denotes supplemented
T16016 32997-33001 IN denotes with
T16017 33002-33005 CD denotes 420
T16018 33006-33008 NNP denotes mM
T16019 33009-33013 NNP denotes NaCl
T16020 33014-33017 CC denotes and
T16021 33018-33020 CD denotes 20
T16022 33020-33021 NN denotes %
T16023 33022-33030 NN denotes glycerol
T16024 33030-33031 -RRB- denotes )
T16025 33031-33032 , denotes ,
T16026 33033-33036 CC denotes and
T16027 33037-33046 VBD denotes incubated
T16028 33047-33049 IN denotes on
T16029 33050-33053 NN denotes ice
T16030 33054-33057 IN denotes for
T16031 33058-33060 CD denotes 20
T16032 33061-33064 NN denotes min
T16033 33064-33065 . denotes .
T16034 33066-33069 DT denotes The
T16035 33070-33081 JJ denotes resuspended
T16036 33082-33088 NN denotes pellet
T16037 33089-33092 VBD denotes was
T16038 33093-33104 VBN denotes centrifuged
T16039 33105-33107 IN denotes at
T16040 33108-33113 CD denotes 15000
T16041 33114-33117 NN denotes rpm
T16042 33118-33121 IN denotes for
T16043 33122-33124 CD denotes 15
T16044 33125-33128 NN denotes min
T16045 33128-33129 , denotes ,
T16046 33130-33133 CC denotes and
T16047 33134-33137 DT denotes the
T16048 33138-33147 VBG denotes resulting
T16049 33148-33155 JJ denotes nuclear
T16050 33156-33164 NNS denotes extracts
T16051 33165-33176 JJ denotes supernatant
T16052 33177-33181 VBD denotes were
T16053 33182-33191 VBN denotes collected
T16054 33192-33194 IN denotes in
T16055 33195-33196 DT denotes a
T16056 33197-33204 VBN denotes chilled
T16057 33205-33214 NNP denotes Eppendorf
T16058 33215-33219 NN denotes tube
T16059 33219-33220 . denotes .
T16060 33221-33230 NNP denotes Consensus
T16061 33231-33247 NNS denotes oligonucleotides
T16062 33248-33252 VBD denotes were
T16063 33253-33264 JJ denotes end-labeled
T16064 33265-33270 VBG denotes using
T16065 33271-33273 CD denotes T4
T16066 33274-33288 NN denotes polynucleotide
T16067 33289-33295 NN denotes kinase
T16068 33296-33299 CC denotes and
T16069 33300-33301 NNP denotes [
T16070 33301-33304 NNP denotes P32
T16071 33304-33305 NNP denotes ]
T16072 33305-33306 : denotes -
T16073 33306-33309 NNP denotes ATP
T16074 33310-33313 IN denotes for
T16075 33314-33316 CD denotes 10
T16076 33317-33320 NN denotes min
T16077 33321-33323 IN denotes at
T16078 33324-33326 CD denotes 37
T16079 33326-33327 CD denotes °
T16080 33327-33328 NNP denotes C
T16081 33328-33329 . denotes .
T16082 33330-33333 DT denotes The
T16083 33334-33337 NN denotes gel
T16084 33338-33343 NN denotes shift
T16085 33344-33353 NNS denotes reactions
T16086 33354-33358 VBD denotes were
T16087 33359-33368 VBN denotes assembled
T16088 33369-33372 CC denotes and
T16089 33373-33382 VBN denotes incubated
T16090 33383-33385 IN denotes at
T16091 33386-33390 NN denotes room
T16092 33391-33402 NN denotes temperature
T16093 33402-33403 . denotes .
T16094 33404-33416 RB denotes Subsequently
T16095 33416-33417 , denotes ,
T16096 33418-33419 CD denotes 1
T16097 33420-33422 NN denotes ml
T16098 33423-33425 IN denotes of
T16099 33426-33429 NN denotes gel
T16100 33430-33437 VBG denotes loading
T16101 33438-33444 NN denotes buffer
T16102 33445-33448 VBD denotes was
T16103 33449-33454 VBN denotes added
T16104 33455-33457 TO denotes to
T16105 33458-33462 DT denotes each
T16106 33463-33471 NN denotes reaction
T16107 33472-33475 CC denotes and
T16108 33476-33482 VBN denotes loaded
T16109 33483-33487 IN denotes onto
T16110 33488-33489 DT denotes a
T16111 33490-33491 CD denotes 6
T16112 33491-33492 NN denotes %
T16113 33493-33509 JJ denotes non-denaturating
T16114 33510-33513 NN denotes gel
T16115 33513-33514 . denotes .
T16116 33515-33518 DT denotes The
T16117 33519-33522 NN denotes gel
T16118 33523-33526 VBD denotes was
T16119 33527-33536 VBN denotes subjected
T16120 33537-33539 TO denotes to
T16121 33540-33555 NN denotes electrophoresis
T16122 33556-33561 IN denotes until
T16123 33562-33565 DT denotes the
T16124 33566-33569 NN denotes dye
T16125 33570-33573 VBD denotes was
T16126 33574-33585 NNS denotes four-fifths
T16127 33586-33588 IN denotes of
T16128 33589-33592 DT denotes the
T16129 33593-33596 NN denotes way
T16130 33597-33601 IN denotes down
T16131 33602-33605 DT denotes the
T16132 33606-33609 NN denotes gel
T16133 33609-33610 . denotes .
T16134 33611-33614 DT denotes The
T16135 33615-33618 NN denotes gel
T16136 33619-33622 VBD denotes was
T16137 33623-33628 VBN denotes dried
T16138 33629-33632 IN denotes for
T16139 33633-33634 CD denotes 1
T16140 33635-33636 NN denotes h
T16141 33637-33639 IN denotes at
T16142 33640-33642 CD denotes 80
T16143 33642-33643 CD denotes °
T16144 33643-33644 NNP denotes C
T16145 33645-33648 CC denotes and
T16146 33649-33656 VBN denotes exposed
T16147 33657-33659 TO denotes to
T16148 33660-33664 NN denotes film
T16149 33665-33674 JJ denotes overnight
T16150 33675-33677 IN denotes at
T16151 33678-33681 CD denotes -70
T16152 33681-33682 CD denotes °
T16153 33682-33684 NNP denotes C.
T16467 33686-33690 NNP denotes Flow
T16468 33691-33701 NNP denotes Cytometric
T16469 33702-33710 NNP denotes Analysis
T16470 33711-33722 NNPS denotes Lymphocytes
T16471 33723-33727 VBD denotes were
T16472 33728-33736 VBN denotes obtained
T16473 33737-33741 IN denotes from
T16474 33742-33747 NN denotes tumor
T16475 33748-33751 CC denotes and
T16476 33752-33758 NN denotes spleen
T16477 33759-33766 NNS denotes tissues
T16478 33767-33770 IN denotes for
T16479 33771-33780 NN denotes phenotype
T16480 33781-33789 NN denotes analysis
T16481 33789-33790 . denotes .
T16482 33791-33797 NNP denotes Spleen
T16483 33798-33801 CC denotes and
T16484 33802-33807 NN denotes tumor
T16485 33808-33819 NNS denotes lymphocytes
T16486 33820-33824 VBD denotes were
T16487 33825-33833 VBN denotes isolated
T16488 33834-33838 IN denotes from
T16489 33839-33844 JJ denotes fresh
T16490 33845-33851 NN denotes spleen
T16491 33852-33855 CC denotes and
T16492 33856-33861 NN denotes tumor
T16493 33862-33870 NNS denotes biopsies
T16494 33871-33879 VBN denotes obtained
T16495 33880-33884 IN denotes from
T16496 33885-33890 CD denotes three
T16497 33891-33895 NNS denotes mice
T16498 33896-33899 IN denotes per
T16499 33900-33905 NN denotes group
T16500 33905-33906 . denotes .
T16501 33907-33913 NNP denotes Spleen
T16502 33914-33917 CC denotes and
T16503 33918-33923 NN denotes tumor
T16504 33924-33932 NNS denotes biopsies
T16505 33933-33937 VBD denotes were
T16506 33938-33945 RB denotes briefly
T16507 33946-33957 VBN denotes homogenized
T16508 33958-33970 RB denotes mechanically
T16509 33971-33973 IN denotes in
T16510 33974-33977 NNP denotes PBS
T16511 33977-33978 , denotes ,
T16512 33979-33987 VBN denotes filtered
T16513 33988-33989 -LRB- denotes (
T16514 33989-33992 CD denotes 100
T16515 33993-33995 NN denotes µm
T16516 33996-34000 NN denotes cell
T16517 34001-34009 NN denotes strainer
T16518 34009-34010 : denotes ;
T16519 34011-34013 NNP denotes BD
T16520 34014-34024 NNP denotes PharMingen
T16521 34024-34025 -RRB- denotes )
T16522 34026-34029 CC denotes and
T16523 34030-34034 RB denotes then
T16524 34035-34041 VBN denotes placed
T16525 34042-34044 IN denotes in
T16526 34045-34050 NN denotes lysis
T16527 34051-34057 NN denotes buffer
T16528 34058-34059 -LRB- denotes (
T16529 34059-34062 NNP denotes ACK
T16530 34063-34069 VBG denotes lysing
T16531 34070-34076 NN denotes buffer
T16532 34076-34077 , denotes ,
T16533 34078-34083 NNP denotes LONZA
T16534 34083-34084 -RRB- denotes )
T16535 34085-34087 TO denotes to
T16536 34088-34094 VB denotes remove
T16537 34095-34098 JJ denotes red
T16538 34099-34104 NN denotes blood
T16539 34105-34110 NNS denotes cells
T16540 34110-34111 . denotes .
T16541 34112-34115 CD denotes One
T16542 34116-34123 CD denotes million
T16543 34124-34135 NNS denotes splenocytes
T16544 34136-34140 VBD denotes were
T16545 34141-34147 VBN denotes washed
T16546 34148-34152 RB denotes once
T16547 34153-34155 IN denotes in
T16548 34156-34159 NNP denotes PBS
T16549 34160-34170 VBG denotes containing
T16550 34171-34172 CD denotes 1
T16551 34172-34173 NN denotes %
T16552 34174-34180 JJ denotes bovine
T16553 34181-34186 NN denotes serum
T16554 34187-34194 NN denotes albumin
T16555 34195-34196 -LRB- denotes (
T16556 34196-34199 NNP denotes BSA
T16557 34199-34200 -RRB- denotes )
T16558 34201-34204 CC denotes and
T16559 34205-34217 JJ denotes re-suspended
T16560 34218-34220 IN denotes in
T16561 34221-34224 CD denotes 100
T16562 34225-34227 NN denotes µl
T16563 34228-34230 IN denotes of
T16564 34231-34238 NNP denotes PBS/BSA
T16565 34239-34245 NN denotes buffer
T16566 34245-34246 . denotes .
T16567 34247-34256 RB denotes Meanwhile
T16568 34256-34257 , denotes ,
T16569 34258-34261 CD denotes one
T16570 34262-34269 CD denotes million
T16571 34270-34275 NNS denotes cells
T16572 34276-34284 VBN denotes obtained
T16573 34285-34289 IN denotes from
T16574 34290-34295 NN denotes tumor
T16575 34296-34303 NNS denotes tissues
T16576 34304-34308 VBD denotes were
T16577 34309-34315 VBN denotes placed
T16578 34316-34318 IN denotes in
T16579 34319-34323 NNP denotes RPMI
T16580 34324-34330 NN denotes medium
T16581 34330-34331 , denotes ,
T16582 34332-34341 VBN denotes incubated
T16583 34342-34344 TO denotes to
T16584 34345-34351 VB denotes obtain
T16585 34352-34362 NN denotes suspension
T16586 34363-34367 NN denotes cell
T16587 34368-34371 IN denotes for
T16588 34372-34377 CD denotes 1hour
T16589 34378-34380 IN denotes at
T16590 34381-34383 CD denotes 37
T16591 34383-34384 CD denotes °
T16592 34384-34385 NNP denotes C
T16593 34385-34386 , denotes ,
T16594 34387-34398 VBN denotes centrifuged
T16595 34399-34400 -LRB- denotes (
T16596 34400-34404 CD denotes 1200
T16597 34405-34408 NN denotes rpm
T16598 34408-34409 , denotes ,
T16599 34410-34411 CD denotes 3
T16600 34412-34415 NN denotes min
T16601 34415-34416 -RRB- denotes )
T16602 34417-34420 CC denotes and
T16603 34421-34425 RB denotes then
T16604 34426-34432 VBD denotes washed
T16605 34433-34435 IN denotes in
T16606 34436-34439 NNP denotes PBS
T16607 34439-34440 . denotes .
T16608 34441-34445 JJ denotes Next
T16609 34445-34446 , denotes ,
T16610 34447-34450 DT denotes the
T16611 34451-34462 NNS denotes lymphocytes
T16612 34463-34467 VBD denotes were
T16613 34468-34477 VBN denotes incubated
T16614 34478-34482 IN denotes with
T16615 34483-34490 JJ denotes various
T16616 34491-34501 VBN denotes conjugated
T16617 34502-34512 JJ denotes monoclonal
T16618 34513-34523 NNS denotes antibodies
T16619 34523-34524 , denotes ,
T16620 34525-34534 VBG denotes including
T16621 34535-34542 NNP denotes CD4-APC
T16622 34542-34543 , denotes ,
T16623 34544-34552 NNP denotes CD8-FITC
T16624 34553-34556 CC denotes and
T16625 34557-34564 NNP denotes CD19-PE
T16626 34565-34568 IN denotes for
T16627 34569-34574 CD denotes 20min
T16628 34575-34577 IN denotes at
T16629 34578-34579 CD denotes 4
T16630 34579-34580 CD denotes °
T16631 34580-34581 NNP denotes C
T16632 34581-34582 , denotes ,
T16633 34583-34589 VBD denotes washed
T16634 34590-34595 RB denotes twice
T16635 34596-34598 IN denotes in
T16636 34599-34602 NNP denotes PBS
T16637 34602-34603 , denotes ,
T16638 34604-34607 CC denotes and
T16639 34608-34620 JJ denotes re-suspended
T16640 34621-34623 IN denotes in
T16641 34624-34627 CD denotes 400
T16642 34628-34630 NN denotes µl
T16643 34631-34633 IN denotes of
T16644 34634-34637 NNP denotes PBS
T16645 34637-34638 . denotes .
T16646 34639-34640 DT denotes A
T16647 34641-34645 NN denotes flow
T16648 34646-34656 JJ denotes cytometric
T16649 34657-34665 NN denotes analysis
T16650 34666-34669 VBD denotes was
T16651 34670-34679 VBN denotes performed
T16652 34680-34682 IN denotes on
T16653 34683-34684 DT denotes a
T16654 34685-34693 NNP denotes FACSAria
T16655 34694-34698 NN denotes flow
T16656 34699-34708 NN denotes cytometry
T16657 34709-34710 -LRB- denotes (
T16658 34710-34712 NNP denotes BD
T16659 34713-34724 NNPS denotes Biosciences
T16660 34724-34725 -RRB- denotes )
T16661 34725-34726 , denotes ,
T16662 34727-34730 CC denotes and
T16663 34731-34734 DT denotes the
T16664 34735-34739 NNS denotes data
T16665 34740-34744 VBD denotes were
T16666 34745-34753 VBN denotes analyzed
T16667 34754-34759 VBG denotes using
T16668 34760-34763 DT denotes the
T16669 34764-34770 NNP denotes WinMDI
T16670 34771-34782 JJ denotes statistical
T16671 34783-34791 NN denotes software
T16672 34792-34793 -LRB- denotes (
T16673 34793-34800 NNP denotes Scripps
T16674 34800-34801 , denotes ,
T16675 34802-34804 NNP denotes La
T16676 34805-34810 NNP denotes Jolla
T16677 34810-34811 , denotes ,
T16678 34812-34814 NNP denotes CA
T16679 34814-34815 , denotes ,
T16680 34816-34819 NNP denotes USA
T16681 34819-34820 -RRB- denotes )
T16682 34820-34821 . denotes .
T16683 34822-34829 RB denotes Forward
T16684 34830-34833 CC denotes and
T16685 34834-34838 NN denotes side
T16686 34839-34846 NN denotes scatter
T16687 34847-34857 NNS denotes parameters
T16688 34858-34862 VBD denotes were
T16689 34863-34867 VBN denotes used
T16690 34868-34870 TO denotes to
T16691 34871-34875 NN denotes gate
T16692 34876-34878 IN denotes on
T16693 34879-34890 NNS denotes lymphocytes
T16694 34890-34891 . denotes .
T16842 34893-34900 NNP denotes Protein
T16843 34901-34914 NNPS denotes Immuno-arrays
T16844 34915-34918 DT denotes The
T16845 34919-34924 NN denotes tumor
T16846 34925-34928 CC denotes and
T16847 34929-34935 NN denotes spleen
T16848 34936-34943 NNS denotes tissues
T16849 34944-34948 VBD denotes were
T16850 34949-34956 VBN denotes excised
T16851 34957-34960 CC denotes and
T16852 34961-34972 VBN denotes homogenized
T16853 34973-34975 IN denotes in
T16854 34976-34979 NNP denotes PBS
T16855 34980-34984 IN denotes with
T16856 34985-34993 NN denotes protease
T16857 34994-35003 NN denotes inhibitor
T16858 35004-35012 NN denotes cocktail
T16859 35013-35014 -LRB- denotes (
T16860 35014-35027 NNP denotes Sigma-Aldrich
T16861 35027-35028 , denotes ,
T16862 35029-35032 NNP denotes USA
T16863 35032-35033 -RRB- denotes )
T16864 35034-35037 CC denotes and
T16865 35038-35044 NNP denotes Triton
T16866 35045-35050 NNP denotes X-100
T16867 35051-35052 -LRB- denotes (
T16868 35052-35057 JJ denotes final
T16869 35058-35071 NN denotes concentration
T16870 35072-35073 CD denotes 1
T16871 35073-35074 NN denotes %
T16872 35074-35075 -RRB- denotes )
T16873 35075-35076 . denotes .
T16874 35077-35080 DT denotes The
T16875 35081-35088 NNS denotes samples
T16876 35089-35093 VBD denotes were
T16877 35094-35100 VBN denotes frozen
T16878 35101-35103 IN denotes at
T16879 35104-35105 CD denotes −
T16880 35105-35107 CD denotes 70
T16881 35107-35108 NN denotes °
T16882 35108-35109 NNP denotes C
T16883 35109-35110 , denotes ,
T16884 35111-35117 VBD denotes thawed
T16885 35117-35118 , denotes ,
T16886 35119-35122 CC denotes and
T16887 35123-35134 VBD denotes centrifuged
T16888 35135-35137 IN denotes at
T16889 35138-35144 CD denotes 10,000
T16890 35144-35145 CD denotes ×
T16891 35145-35146 NN denotes g
T16892 35147-35150 IN denotes for
T16893 35151-35152 CD denotes 5
T16894 35153-35156 NN denotes min
T16895 35157-35159 TO denotes to
T16896 35160-35166 VB denotes remove
T16897 35167-35175 JJ denotes cellular
T16898 35176-35182 NN denotes debris
T16899 35182-35183 . denotes .
T16900 35184-35187 DT denotes The
T16901 35188-35194 NN denotes tissue
T16902 35195-35202 VBZ denotes lysates
T16903 35203-35207 VBD denotes were
T16904 35208-35217 VBN denotes performed
T16905 35218-35225 NN denotes protein
T16906 35226-35231 NN denotes assay
T16907 35232-35234 IN denotes in
T16908 35235-35238 DT denotes the
T16909 35239-35243 JJ denotes same
T16910 35244-35247 NN denotes way
T16911 35248-35250 IN denotes as
T16912 35251-35254 IN denotes for
T16913 35255-35262 JJ denotes western
T16914 35263-35271 VBG denotes blotting
T16915 35271-35272 . denotes .
T16916 35273-35276 CD denotes 4.5
T16917 35277-35279 NN denotes mg
T16918 35280-35282 IN denotes of
T16919 35283-35291 NNS denotes proteins
T16920 35291-35292 , denotes ,
T16921 35293-35302 VBN denotes collected
T16922 35303-35307 IN denotes from
T16923 35308-35313 CD denotes three
T16924 35314-35321 NNS denotes samples
T16925 35322-35325 IN denotes per
T16926 35326-35331 NN denotes group
T16927 35331-35332 , denotes ,
T16928 35333-35337 VBD denotes were
T16929 35338-35342 VBN denotes used
T16930 35343-35346 IN denotes for
T16931 35347-35352 NNP denotes Mouse
T16932 35353-35361 NN denotes cytokine
T16933 35362-35367 NN denotes array
T16934 35368-35370 IN denotes as
T16935 35371-35374 DT denotes the
T16936 35375-35383 NN denotes protocol
T16937 35384-35392 VBN denotes provided
T16938 35393-35395 IN denotes by
T16939 35396-35404 NN denotes supplier
T16940 35405-35406 -LRB- denotes (
T16941 35406-35414 NNP denotes Proteome
T16942 35415-35423 NNP denotes Profiler
T16943 35423-35424 NNP denotes ™
T16944 35424-35425 , denotes ,
T16945 35426-35430 NNP denotes #ARY
T16946 35430-35433 CD denotes 006
T16947 35433-35434 , denotes ,
T16948 35435-35438 NNP denotes R&D
T16949 35439-35446 NNPS denotes Systems
T16950 35446-35447 , denotes ,
T16951 35448-35451 NNP denotes USA
T16952 35451-35452 -RRB- denotes )
T16953 35452-35453 . denotes .
T17081 35455-35466 NNP denotes Statistical
T17082 35467-35475 NNP denotes Analysis
T17083 35476-35479 NNP denotes The
T17084 35480-35484 NNS denotes data
T17085 35485-35489 VBD denotes were
T17086 35490-35498 VBN denotes analyzed
T17087 35499-35504 VBG denotes using
T17088 35505-35508 DT denotes the
T17089 35509-35517 NNP denotes GraphPad
T17090 35518-35523 NNP denotes Prism
T17091 35524-35525 CD denotes 4
T17092 35526-35529 NN denotes ver
T17093 35529-35530 . denotes .
T17094 35531-35535 CD denotes 4.03
T17095 35536-35544 NN denotes software
T17096 35545-35546 -LRB- denotes (
T17097 35546-35554 NNP denotes GraphPad
T17098 35555-35563 NNP denotes Software
T17099 35563-35564 , denotes ,
T17100 35565-35567 NNP denotes La
T17101 35568-35573 NNP denotes Jolla
T17102 35573-35574 , denotes ,
T17103 35575-35577 NNP denotes CA
T17104 35577-35578 -RRB- denotes )
T17105 35578-35579 . denotes .
T17106 35580-35584 NNS denotes Data
T17107 35585-35588 VBP denotes are
T17108 35589-35598 VBN denotes presented
T17109 35599-35601 IN denotes as
T17110 35602-35606 JJ denotes mean
T17111 35607-35608 NN denotes ±
T17112 35609-35611 NNP denotes SD
T17113 35611-35612 . denotes .
T17114 35613-35623 NN denotes Difference
T17115 35624-35631 IN denotes between
T17116 35632-35636 CD denotes CCR5
T17117 35636-35637 CD denotes −
T17118 35637-35638 NN denotes /
T17119 35638-35639 NN denotes −
T17120 35640-35644 NNS denotes mice
T17121 35645-35648 CC denotes and
T17122 35649-35653 NNS denotes CCR5
T17123 35653-35654 VBP denotes +
T17124 35654-35655 CD denotes /
T17125 35655-35656 CD denotes +
T17126 35657-35661 NNS denotes mice
T17127 35662-35666 VBD denotes were
T17128 35667-35675 VBN denotes compared
T17129 35676-35681 VBG denotes using
T17130 35682-35683 JJ denotes t
T17131 35684-35688 NN denotes test
T17132 35688-35689 . denotes .
T17133 35690-35691 DT denotes A
T17134 35692-35697 NN denotes value
T17135 35698-35700 IN denotes of
T17136 35701-35702 NN denotes p
T17137 35702-35703 NN denotes <
T17138 35703-35707 CD denotes 0.05
T17139 35708-35711 VBD denotes was
T17140 35712-35722 VBN denotes considered
T17141 35723-35725 TO denotes to
T17142 35726-35728 VB denotes be
T17143 35729-35742 RB denotes statistically
T17144 35743-35754 JJ denotes significant
T17145 35754-35755 . denotes .
T17146 35756-35764 NN denotes Survival
T17147 35765-35769 NNS denotes data
T17148 35770-35774 VBD denotes were
T17149 35775-35784 VBN denotes presented
T17150 35785-35787 IN denotes by
T17151 35788-35800 NNP denotes Kaplan-Meier
T17152 35801-35809 NN denotes survival
T17153 35810-35819 NNS denotes estimates
T17154 35820-35823 CC denotes and
T17155 35824-35832 VBN denotes compared
T17156 35833-35836 CC denotes and
T17157 35837-35847 VBN denotes calculated
T17158 35848-35850 IN denotes by
T17159 35851-35859 JJ denotes Log-rank
T17160 35860-35861 -LRB- denotes (
T17161 35861-35871 NNP denotes Mantel-Cox
T17162 35871-35872 -RRB- denotes )
T17163 35873-35877 NN denotes Test
T17164 35878-35880 IN denotes in
T17165 35881-35889 NNP denotes GraphPad
T17166 35890-35895 NNP denotes Prism
T17167 35895-35896 . denotes .
R10000 T14434 T14433 pobj ice,on
R10001 T14435 T14411 punct .,homogenized
R10002 T14436 T14438 det The,lysate
R10003 T14437 T14438 compound tissue,lysate
R10004 T14438 T14439 nsubj lysate,centrifuged
R10005 T14439 T14439 ROOT centrifuged,centrifuged
R10006 T14440 T14439 prep at,centrifuged
R10007 T14441 T14442 nummod "15,000",rpm
R10008 T14442 T14440 pobj rpm,at
R10009 T14443 T14439 prep for,centrifuged
R10010 T14444 T14445 nummod 15,min
R10011 T14445 T14443 pobj min,for
R10012 T14446 T14445 prep at,min
R10013 T14447 T14448 nummod 4,°
R10014 T14448 T14451 nummod °,amounts
R10015 T14449 T14450 compound C.,Equal
R10016 T14450 T14451 compound Equal,amounts
R10017 T14451 T14459 nsubjpass amounts,separated
R10018 T14452 T14451 prep of,amounts
R10019 T14453 T14452 pobj proteins,of
R10020 T14454 T14453 punct (,proteins
R10021 T14455 T14456 nummod 40,µg
R10022 T14456 T14453 appos µg,proteins
R10023 T14457 T14453 punct ),proteins
R10024 T14458 T14459 auxpass were,separated
R10025 T14459 T14439 conj separated,centrifuged
R10026 T14460 T14459 prep on,separated
R10027 T14461 T14466 det a,gel
R10028 T14462 T14463 nummod SDS/12,%
R10029 T14463 T14466 compound %,gel
R10030 T14464 T14465 punct -,polyacrylamide
R10031 T14465 T14466 compound polyacrylamide,gel
R10032 T14466 T14460 pobj gel,on
R10033 T14467 T14459 punct ",",separated
R10034 T14468 T14459 cc and,separated
R10035 T14469 T14470 advmod then,transferred
R10036 T14470 T14459 conj transferred,separated
R10037 T14471 T14470 prep to,transferred
R10038 T14472 T14474 det a,difluoride
R10039 T14473 T14474 compound polyvinylidene,difluoride
R10040 T14474 T14471 pobj difluoride,to
R10041 T14475 T14474 punct (,difluoride
R10042 T14476 T14478 nmod PVDF,membrane
R10043 T14477 T14478 punct ),membrane
R10044 T14478 T14481 nmod membrane,Water
R10045 T14479 T14481 punct (,Water
R10046 T14480 T14481 compound GE,Water
R10047 T14481 T14484 nmod Water,technologies
R10048 T14482 T14481 cc and,Water
R10049 T14483 T14481 conj Process,Water
R10050 T14484 T14474 appos technologies,difluoride
R10051 T14485 T14484 punct ",",technologies
R10052 T14486 T14484 appos Trevose,technologies
R10053 T14487 T14486 punct ",",Trevose
R10054 T14488 T14486 conj PA,Trevose
R10055 T14489 T14488 punct ",",PA
R10056 T14490 T14488 conj USA,PA
R10057 T14491 T14484 punct ),technologies
R10058 T14492 T14459 punct .,separated
R10059 T14493 T14495 nsubjpass Blots,blocked
R10060 T14494 T14495 auxpass were,blocked
R10061 T14495 T14495 ROOT blocked,blocked
R10062 T14496 T14495 prep for,blocked
R10063 T14497 T14498 nummod 1,h
R10064 T14498 T14496 pobj h,for
R10065 T14499 T14498 prep at,h
R10066 T14500 T14501 compound room,temperature
R10067 T14501 T14499 pobj temperature,at
R10068 T14502 T14495 prep with,blocked
R10069 T14503 T14504 nummod 5,%
R10070 T14504 T14502 pobj %,with
R10071 T14505 T14506 punct (,w/v
R10072 T14506 T14504 appos w/v,%
R10073 T14507 T14495 punct ),blocked
R10074 T14508 T14510 amod non-fat,milk
R10075 T14509 T14510 amod dried,milk
R10076 T14510 T14510 ROOT milk,milk
R10077 T14511 T14510 prep in,milk
R10078 T14512 T14516 compound Tris-Buffered,TBST
R10079 T14513 T14516 compound Saline,TBST
R10080 T14514 T14516 compound Tween-20,TBST
R10081 T14515 T14516 compound [,TBST
R10082 T14516 T14511 pobj TBST,in
R10083 T14517 T14510 punct :,milk
R10084 T14518 T14520 nummod 10,Tris
R10085 T14519 T14520 compound mM,Tris
R10086 T14520 T14510 appos Tris,milk
R10087 T14521 T14522 punct (,pH
R10088 T14522 T14520 appos pH,Tris
R10089 T14523 T14522 nummod 8.0,pH
R10090 T14524 T14522 punct ),pH
R10091 T14525 T14520 cc and,Tris
R10092 T14526 T14529 nummod 150,solution
R10093 T14527 T14529 compound mM,solution
R10094 T14528 T14529 compound NaCl,solution
R10095 T14529 T14520 conj solution,Tris
R10096 T14530 T14529 acl containing,solution
R10097 T14531 T14532 nummod 0.05,%
R10098 T14532 T14530 dobj %,containing
R10099 T14533 T14534 nummod Tween-20,]
R10100 T14534 T14530 dobj ],containing
R10101 T14535 T14510 punct .,milk
R10102 T14536 T14546 prep After,immunoblotted
R10103 T14537 T14539 det a,washing
R10104 T14538 T14539 amod short,washing
R10105 T14539 T14536 pobj washing,After
R10106 T14540 T14539 prep in,washing
R10107 T14541 T14540 pobj TBST,in
R10108 T14542 T14546 punct ",",immunoblotted
R10109 T14543 T14544 det the,membranes
R10110 T14544 T14546 nsubjpass membranes,immunoblotted
R10111 T14545 T14546 auxpass were,immunoblotted
R10112 T14546 T14546 ROOT immunoblotted,immunoblotted
R10113 T14547 T14546 prep with,immunoblotted
R10114 T14548 T14551 det the,antibodies
R10115 T14549 T14551 amod following,antibodies
R10116 T14550 T14551 amod primary,antibodies
R10117 T14551 T14547 pobj antibodies,with
R10118 T14552 T14551 punct :,antibodies
R10119 T14553 T14555 amod mouse,antibodies
R10120 T14554 T14555 amod monoclonal,antibodies
R10121 T14555 T14551 appos antibodies,antibodies
R10122 T14556 T14551 acl directed,antibodies
R10123 T14557 T14556 prep against,directed
R10124 T14558 T14557 pobj p65,against
R10125 T14559 T14558 cc and,p65
R10126 T14560 T14558 conj p50,p65
R10127 T14561 T14562 punct (,1
R10128 T14562 T14565 nummod 1,dilutions
R10129 T14563 T14565 nmod ∶,dilutions
R10130 T14564 T14565 nummod 500,dilutions
R10131 T14565 T14551 appos dilutions,antibodies
R10132 T14566 T14546 punct ;,immunoblotted
R10133 T14567 T14568 compound Santa,Cruz
R10134 T14568 T14569 compound Cruz,Biotechnology
R10135 T14569 T14579 nmod Biotechnology,antibodies
R10136 T14570 T14569 punct ",",Biotechnology
R10137 T14571 T14572 compound Santa,Cruz
R10138 T14572 T14569 conj Cruz,Biotechnology
R10139 T14573 T14572 punct ",",Cruz
R10140 T14574 T14572 conj CA,Cruz
R10141 T14575 T14572 punct ),Cruz
R10142 T14576 T14572 punct ",",Cruz
R10143 T14577 T14579 compound rabbit,antibodies
R10144 T14578 T14579 compound polyclonal,antibodies
R10145 T14579 T14580 nsubj antibodies,directed
R10146 T14580 T14546 conj directed,immunoblotted
R10147 T14581 T14580 prep against,directed
R10148 T14582 T14581 pobj Bax,against
R10149 T14583 T14582 cc and,Bax
R10150 T14584 T14582 conj PARP,Bax
R10151 T14585 T14586 punct (,1
R10152 T14586 T14584 nummod 1,PARP
R10153 T14587 T14589 nummod ∶,dilutions
R10154 T14588 T14589 nummod 500,dilutions
R10155 T14589 T14546 npadvmod dilutions,immunoblotted
R10156 T14590 T14546 punct ;,immunoblotted
R10157 T14591 T14592 compound Santa,Cruz
R10158 T14592 T14593 compound Cruz,Biotechnology
R10159 T14593 T14546 dobj Biotechnology,immunoblotted
R10160 T14594 T14593 punct ),Biotechnology
R10161 T14595 T14593 punct ",",Biotechnology
R10162 T14596 T14546 cc and,immunoblotted
R10163 T14597 T14546 prep against,immunoblotted
R10164 T14598 T14613 amod caspase-3,Technology
R10165 T14599 T14598 punct ",",caspase-3
R10166 T14600 T14598 conj caspase-9,caspase-3
R10167 T14601 T14600 punct ",",caspase-9
R10168 T14602 T14600 conj Bcl-2,caspase-9
R10169 T14603 T14602 cc and,Bcl-2
R10170 T14604 T14602 conj c-IAP-1,Bcl-2
R10171 T14605 T14609 punct (,dilutions
R10172 T14606 T14609 nummod 1,dilutions
R10173 T14607 T14609 nmod ∶,dilutions
R10174 T14608 T14609 nummod 1000,dilutions
R10175 T14609 T14598 dep dilutions,caspase-3
R10176 T14610 T14613 punct ;,Technology
R10177 T14611 T14613 compound Cell,Technology
R10178 T14612 T14613 compound Signaling,Technology
R10179 T14613 T14597 pobj Technology,against
R10180 T14614 T14613 punct ",",Technology
R10181 T14615 T14613 conj Beverly,Technology
R10182 T14616 T14615 punct ",",Beverly
R10183 T14617 T14615 conj MA,Beverly
R10184 T14618 T14617 punct ),MA
R10185 T14619 T14546 punct .,immunoblotted
R10186 T14620 T14621 det The,blots
R10187 T14621 T14623 nsubjpass blots,incubated
R10188 T14622 T14623 auxpass were,incubated
R10189 T14623 T14623 ROOT incubated,incubated
R10190 T14624 T14623 prep with,incubated
R10191 T14625 T14632 det the,IgG
R10192 T14626 T14629 amod respective,anti-rabbit
R10193 T14627 T14629 amod horseradish,anti-rabbit
R10194 T14628 T14629 compound peroxidase-conjugated,anti-rabbit
R10195 T14629 T14632 amod anti-rabbit,IgG
R10196 T14630 T14629 cc or,anti-rabbit
R10197 T14631 T14629 conj anti-mouse,anti-rabbit
R10198 T14632 T14624 pobj IgG,with
R10199 T14633 T14634 punct (,1
R10200 T14634 T14636 compound 1,4000
R10201 T14635 T14636 compound ∶,4000
R10202 T14636 T14637 nummod 4000,dilutions
R10203 T14637 T14623 npadvmod dilutions,incubated
R10204 T14638 T14623 punct ;,incubated
R10205 T14639 T14640 compound Santa,Cruz
R10206 T14640 T14641 compound Cruz,Biotechnology
R10207 T14641 T14641 ROOT Biotechnology,Biotechnology
R10208 T14642 T14623 punct ),incubated
R10209 T14643 T14623 punct .,incubated
R10210 T14644 T14645 amod Immunoreactive,proteins
R10211 T14645 T14647 nsubjpass proteins,detected
R10212 T14646 T14647 auxpass were,detected
R10213 T14647 T14647 ROOT detected,detected
R10214 T14648 T14647 prep with,detected
R10215 T14649 T14652 det the,system
R10216 T14650 T14652 compound ECL,system
R10217 T14651 T14652 compound detection,system
R10218 T14652 T14648 pobj system,with
R10219 T14653 T14647 punct .,detected
R10564 T15029 T15033 nsubjpass Immunohistochemistry,fixed
R10565 T15030 T15031 det All,specimens
R10566 T15031 T15033 nsubjpass specimens,fixed
R10567 T15032 T15033 auxpass were,fixed
R10568 T15033 T15033 ROOT fixed,fixed
R10569 T15034 T15033 prep in,fixed
R10570 T15035 T15034 pobj formalin,in
R10571 T15036 T15033 cc and,fixed
R10572 T15037 T15033 conj embedded,fixed
R10573 T15038 T15037 prep in,embedded
R10574 T15039 T15038 pobj paraffin,in
R10575 T15040 T15037 prep for,embedded
R10576 T15041 T15040 pobj examination,for
R10577 T15042 T15033 punct .,fixed
R10578 T15043 T15050 nsubjpass Sections,stained
R10579 T15044 T15043 punct (,Sections
R10580 T15045 T15046 nummod 4,µm
R10581 T15046 T15047 npadvmod µm,thick
R10582 T15047 T15043 appos thick,Sections
R10583 T15048 T15043 punct ),Sections
R10584 T15049 T15050 auxpass were,stained
R10585 T15050 T15050 ROOT stained,stained
R10586 T15051 T15050 prep with,stained
R10587 T15052 T15051 pobj H&E,with
R10588 T15053 T15050 cc and,stained
R10589 T15054 T15050 conj analyzed,stained
R10590 T15055 T15054 agent by,analyzed
R10591 T15056 T15055 pobj immunohistochemistry,by
R10592 T15057 T15050 punct .,stained
R10593 T15058 T15060 det The,sections
R10594 T15059 T15060 amod paraffin-embedded,sections
R10595 T15060 T15062 nsubjpass sections,deparaffinized
R10596 T15061 T15062 auxpass were,deparaffinized
R10597 T15062 T15062 ROOT deparaffinized,deparaffinized
R10598 T15063 T15062 cc and,deparaffinized
R10599 T15064 T15062 conj rehydrated,deparaffinized
R10600 T15065 T15064 punct ",",rehydrated
R10601 T15066 T15064 conj washed,rehydrated
R10602 T15067 T15066 prep in,washed
R10603 T15068 T15069 amod distilled,water
R10604 T15069 T15067 pobj water,in
R10605 T15070 T15066 punct ",",washed
R10606 T15071 T15066 cc and,washed
R10607 T15072 T15073 advmod then,subjected
R10608 T15073 T15066 conj subjected,washed
R10609 T15074 T15073 prep to,subjected
R10610 T15075 T15077 amod heat-mediated,retrieval
R10611 T15076 T15077 compound antigen,retrieval
R10612 T15077 T15074 pobj retrieval,to
R10613 T15078 T15062 punct .,deparaffinized
R10614 T15079 T15081 amod Endogenous,activity
R10615 T15080 T15081 compound peroxidase,activity
R10616 T15081 T15083 nsubjpass activity,quenched
R10617 T15082 T15083 auxpass was,quenched
R10618 T15083 T15083 ROOT quenched,quenched
R10619 T15084 T15083 agent by,quenched
R10620 T15085 T15084 pobj incubation,by
R10621 T15086 T15083 prep in,quenched
R10622 T15087 T15088 nummod 3,%
R10623 T15088 T15090 compound %,peroxide
R10624 T15089 T15090 compound hydrogen,peroxide
R10625 T15090 T15086 pobj peroxide,in
R10626 T15091 T15083 prep in,quenched
R10627 T15092 T15091 pobj methanol,in
R10628 T15093 T15083 prep for,quenched
R10629 T15094 T15095 nummod 15,min
R10630 T15095 T15093 pobj min,for
R10631 T15096 T15095 punct ",",min
R10632 T15097 T15083 advcl followed,quenched
R10633 T15098 T15097 prep by,followed
R10634 T15099 T15098 pcomp clearing,by
R10635 T15100 T15099 prep in,clearing
R10636 T15101 T15100 pobj PBS,in
R10637 T15102 T15099 prep for,clearing
R10638 T15103 T15104 nummod 5,min
R10639 T15104 T15102 pobj min,for
R10640 T15105 T15083 punct .,quenched
R10641 T15106 T15107 det The,sections
R10642 T15107 T15109 nsubjpass sections,blocked
R10643 T15108 T15109 auxpass were,blocked
R10644 T15109 T15109 ROOT blocked,blocked
R10645 T15110 T15109 prep for,blocked
R10646 T15111 T15112 nummod 30,min
R10647 T15112 T15110 pobj min,for
R10648 T15113 T15112 prep with,min
R10649 T15114 T15115 nummod 3,%
R10650 T15115 T15123 compound %,blotted
R10651 T15116 T15118 amod normal,serum
R10652 T15117 T15118 compound horse,serum
R10653 T15118 T15123 nsubj serum,blotted
R10654 T15119 T15118 acl diluted,serum
R10655 T15120 T15119 prep in,diluted
R10656 T15121 T15120 pobj PBS,in
R10657 T15122 T15118 punct ",",serum
R10658 T15123 T15109 advcl blotted,blocked
R10659 T15124 T15123 punct ",",blotted
R10660 T15125 T15123 cc and,blotted
R10661 T15126 T15123 conj incubated,blotted
R10662 T15127 T15126 prep with,incubated
R10663 T15128 T15129 amod primary,mouse
R10664 T15129 T15134 nmod mouse,antigen
R10665 T15130 T15134 amod anti-mouse,antigen
R10666 T15131 T15134 amod proliferating,antigen
R10667 T15132 T15134 compound cell,antigen
R10668 T15133 T15134 amod nuclear,antigen
R10669 T15134 T15127 pobj antigen,with
R10670 T15135 T15134 punct (,antigen
R10671 T15136 T15134 appos PCNA,antigen
R10672 T15137 T15136 punct ",",PCNA
R10673 T15138 T15140 nummod 1,200
R10674 T15139 T15140 nummod ∶,200
R10675 T15140 T15141 npadvmod 200,dilution
R10676 T15141 T15136 appos dilution,PCNA
R10677 T15142 T15136 punct ),PCNA
R10678 T15143 T15144 amod monoclonal,antibodies
R10679 T15144 T15134 appos antibodies,antigen
R10680 T15145 T15126 prep in,incubated
R10681 T15146 T15145 pcomp blocking,in
R10682 T15147 T15146 dobj serum,blocking
R10683 T15148 T15146 prep for,blocking
R10684 T15149 T15150 nummod 4,h
R10685 T15150 T15148 pobj h,for
R10686 T15151 T15150 prep at,h
R10687 T15152 T15153 compound room,temperature
R10688 T15153 T15151 pobj temperature,at
R10689 T15154 T15109 punct .,blocked
R10690 T15155 T15160 advmod Thereafter,washed
R10691 T15156 T15160 punct ",",washed
R10692 T15157 T15158 det the,slides
R10693 T15158 T15160 nsubjpass slides,washed
R10694 T15159 T15160 auxpass were,washed
R10695 T15160 T15160 ROOT washed,washed
R10696 T15161 T15162 nummod three,times
R10697 T15162 T15160 npadvmod times,washed
R10698 T15163 T15160 prep for,washed
R10699 T15164 T15165 nummod 5,min
R10700 T15165 T15163 pobj min,for
R10701 T15166 T15170 nsubj each,incubated
R10702 T15167 T15166 prep in,each
R10703 T15168 T15167 pobj PBS,in
R10704 T15169 T15166 cc and,each
R10705 T15170 T15160 advcl incubated,washed
R10706 T15171 T15170 prep with,incubated
R10707 T15172 T15173 amod biotinylated,anti-mouse
R10708 T15173 T15171 pobj anti-mouse,with
R10709 T15174 T15173 cc and,anti-mouse
R10710 T15175 T15176 amod anti-rabbit,antibodies
R10711 T15176 T15173 conj antibodies,anti-mouse
R10712 T15177 T15170 prep for,incubated
R10713 T15178 T15179 nummod 2,h
R10714 T15179 T15177 pobj h,for
R10715 T15180 T15160 punct .,washed
R10716 T15181 T15182 det The,slides
R10717 T15182 T15184 nsubjpass slides,washed
R10718 T15183 T15184 auxpass were,washed
R10719 T15184 T15203 ccomp washed,Laboratories
R10720 T15185 T15184 prep in,washed
R10721 T15186 T15185 pobj PBS,in
R10722 T15187 T15184 punct ",",washed
R10723 T15188 T15184 advcl followed,washed
R10724 T15189 T15188 agent by,followed
R10725 T15190 T15191 det the,addition
R10726 T15191 T15189 pobj addition,by
R10727 T15192 T15191 prep of,addition
R10728 T15193 T15197 det the,complex
R10729 T15194 T15197 nmod avidin,complex
R10730 T15195 T15197 nmod biotin,complex
R10731 T15196 T15197 compound peroxidase,complex
R10732 T15197 T15200 amod complex,kit
R10733 T15198 T15200 punct (,kit
R10734 T15199 T15200 compound ABC,kit
R10735 T15200 T15192 pobj kit,of
R10736 T15201 T15203 punct ;,Laboratories
R10737 T15202 T15203 compound Vector,Laboratories
R10738 T15203 T15203 ROOT Laboratories,Laboratories
R10739 T15204 T15203 punct ",",Laboratories
R10740 T15205 T15203 conj Burlingame,Laboratories
R10741 T15206 T15205 punct ",",Burlingame
R10742 T15207 T15205 conj CA,Burlingame
R10743 T15208 T15207 punct ",",CA
R10744 T15209 T15207 conj USA,CA
R10745 T15210 T15205 punct ),Burlingame
R10746 T15211 T15203 punct .,Laboratories
R10747 T15212 T15213 det The,slides
R10748 T15213 T15215 nsubjpass slides,washed
R10749 T15214 T15215 auxpass were,washed
R10750 T15215 T15215 ROOT washed,washed
R10751 T15216 T15215 cc and,washed
R10752 T15217 T15219 det the,reaction
R10753 T15218 T15219 amod peroxidase,reaction
R10754 T15219 T15221 nsubjpass reaction,developed
R10755 T15220 T15221 auxpass was,developed
R10756 T15221 T15215 conj developed,washed
R10757 T15222 T15221 prep with,developed
R10758 T15223 T15222 pobj diaminobenzidine,with
R10759 T15224 T15225 punct (,DAB
R10760 T15225 T15223 appos DAB,diaminobenzidine
R10761 T15226 T15225 punct ),DAB
R10762 T15227 T15223 cc and,diaminobenzidine
R10763 T15228 T15223 conj peroxide,diaminobenzidine
R10764 T15229 T15221 punct ",",developed
R10765 T15230 T15221 advcl followed,developed
R10766 T15231 T15221 agent by,developed
R10767 T15232 T15231 pcomp counterstaining,by
R10768 T15233 T15232 prep with,counterstaining
R10769 T15234 T15233 pobj hematoxylin,with
R10770 T15235 T15232 punct ",",counterstaining
R10771 T15236 T15232 conj mounting,counterstaining
R10772 T15237 T15236 prep in,mounting
R10773 T15238 T15237 pobj aqua-mount,in
R10774 T15239 T15236 punct ",",mounting
R10775 T15240 T15236 cc and,mounting
R10776 T15241 T15236 conj evaluation,mounting
R10777 T15242 T15241 prep under,evaluation
R10778 T15243 T15245 det a,microscope
R10779 T15244 T15245 amod light,microscope
R10780 T15245 T15242 pobj microscope,under
R10781 T15246 T15248 punct (,×
R10782 T15247 T15248 nsubj magnification,×
R10783 T15248 T15241 parataxis ×,evaluation
R10784 T15249 T15248 npadvmod 200,×
R10785 T15250 T15248 punct ;,×
R10786 T15251 T15248 conj Olympus,×
R10787 T15252 T15251 punct ",",Olympus
R10788 T15253 T15251 conj Tokyo,Olympus
R10789 T15254 T15253 punct ",",Tokyo
R10790 T15255 T15253 conj Japan,Tokyo
R10791 T15256 T15253 punct ),Tokyo
R10792 T15257 T15221 punct .,developed
R10793 T15258 T15260 det A,control
R10794 T15259 T15260 amod negative,control
R10795 T15260 T15262 nsubjpass control,included
R10796 T15261 T15262 auxpass was,included
R10797 T15262 T15262 ROOT included,included
R10798 T15263 T15262 prep in,included
R10799 T15264 T15265 det all,experiments
R10800 T15265 T15263 pobj experiments,in
R10801 T15266 T15262 prep by,included
R10802 T15267 T15266 pcomp omitting,by
R10803 T15268 T15270 det the,antibody
R10804 T15269 T15270 amod primary,antibody
R10805 T15270 T15267 dobj antibody,omitting
R10806 T15271 T15262 punct .,included
R10807 T15272 T15288 prep For,incubated
R10808 T15273 T15274 det the,detection
R10809 T15274 T15272 pobj detection,For
R10810 T15275 T15274 prep of,detection
R10811 T15276 T15278 amod apoptotic,death
R10812 T15277 T15278 compound cell,death
R10813 T15278 T15275 pobj death,of
R10814 T15279 T15274 prep in,detection
R10815 T15280 T15282 det the,tissues
R10816 T15281 T15282 compound tumor,tissues
R10817 T15282 T15279 pobj tissues,in
R10818 T15283 T15288 punct ",",incubated
R10819 T15284 T15286 det the,sections
R10820 T15285 T15286 amod paraffin-embedded,sections
R10821 T15286 T15288 nsubjpass sections,incubated
R10822 T15287 T15288 auxpass were,incubated
R10823 T15288 T15288 ROOT incubated,incubated
R10824 T15289 T15288 prep in,incubated
R10825 T15290 T15291 det a,mixture
R10826 T15291 T15289 pobj mixture,in
R10827 T15292 T15291 prep of,mixture
R10828 T15293 T15295 det the,solution
R10829 T15294 T15295 amod labeling,solution
R10830 T15295 T15292 pobj solution,of
R10831 T15296 T15295 punct (,solution
R10832 T15297 T15298 nummod 540,µl
R10833 T15298 T15295 appos µl,solution
R10834 T15299 T15295 punct ),solution
R10835 T15300 T15288 cc and,incubated
R10836 T15301 T15302 compound enzyme,solution
R10837 T15302 T15288 conj solution,incubated
R10838 T15303 T15305 punct (,µl
R10839 T15304 T15305 nummod 60,µl
R10840 T15305 T15302 appos µl,solution
R10841 T15306 T15302 punct ),solution
R10842 T15307 T15302 prep for,solution
R10843 T15308 T15309 nummod 1,h
R10844 T15309 T15307 pobj h,for
R10845 T15310 T15302 prep at,solution
R10846 T15311 T15312 nummod 37,°
R10847 T15312 T15310 pobj °,at
R10848 T15313 T15302 npadvmod C,solution
R10849 T15314 T15302 punct ",",solution
R10850 T15315 T15288 cc and,incubated
R10851 T15316 T15317 advmod then,washed
R10852 T15317 T15288 conj washed,incubated
R10853 T15318 T15319 nummod three,times
R10854 T15319 T15317 npadvmod times,washed
R10855 T15320 T15317 prep in,washed
R10856 T15321 T15323 nummod 0.1,PBS
R10857 T15322 T15323 compound M,PBS
R10858 T15323 T15320 pobj PBS,in
R10859 T15324 T15317 prep for,washed
R10860 T15325 T15326 nummod 5,min
R10861 T15326 T15324 pobj min,for
R10862 T15327 T15326 appos each,min
R10863 T15328 T15317 punct ",",washed
R10864 T15329 T15317 prep according,washed
R10865 T15330 T15329 prep to,according
R10866 T15331 T15332 det the,manufacturer
R10867 T15332 T15333 poss manufacturer,instructions
R10868 T15333 T15330 pobj instructions,to
R10869 T15334 T15288 punct .,incubated
R10870 T15335 T15340 advmod Next,incubated
R10871 T15336 T15340 punct ",",incubated
R10872 T15337 T15338 det the,sections
R10873 T15338 T15340 nsubjpass sections,incubated
R10874 T15339 T15340 auxpass were,incubated
R10875 T15340 T15340 ROOT incubated,incubated
R10876 T15341 T15340 prep with,incubated
R10877 T15342 T15343 nummod 4,′
R10878 T15343 T15341 pobj ′,with
R10879 T15344 T15346 punct ",6",diamidino-2-phenylindole
R10880 T15345 T15346 punct -,diamidino-2-phenylindole
R10881 T15346 T15346 ROOT diamidino-2-phenylindole,diamidino-2-phenylindole
R10882 T15347 T15348 punct (,DAPI
R10883 T15348 T15346 appos DAPI,diamidino-2-phenylindole
R10884 T15349 T15346 punct ),diamidino-2-phenylindole
R10885 T15350 T15346 prep for,diamidino-2-phenylindole
R10886 T15351 T15352 nummod 15,min
R10887 T15352 T15350 pobj min,for
R10888 T15353 T15346 prep at,diamidino-2-phenylindole
R10889 T15354 T15355 nummod 37,°
R10890 T15355 T15353 pobj °,at
R10891 T15356 T15353 pobj C.,at
R10892 T15357 T15362 advmod Finally,rinsed
R10893 T15358 T15362 punct ",",rinsed
R10894 T15359 T15360 det the,sections
R10895 T15360 T15362 nsubjpass sections,rinsed
R10896 T15361 T15362 auxpass were,rinsed
R10897 T15362 T15362 ROOT rinsed,rinsed
R10898 T15363 T15362 punct ",",rinsed
R10899 T15364 T15362 conj mounted,rinsed
R10900 T15365 T15364 prep on,mounted
R10901 T15366 T15365 pobj slides,on
R10902 T15367 T15365 punct ",",on
R10903 T15368 T15364 cc and,mounted
R10904 T15369 T15364 conj cover-slipped,mounted
R10905 T15370 T15369 prep for,cover-slipped
R10906 T15371 T15372 compound fluorescence,microscopy
R10907 T15372 T15370 pobj microscopy,for
R10908 T15373 T15375 punct (,microscope
R10909 T15374 T15375 compound DAS,microscope
R10910 T15375 T15372 appos microscope,microscopy
R10911 T15376 T15372 punct ),microscopy
R10912 T15377 T15362 punct .,rinsed
R10949 T15506 T15507 compound Immunofluorescence,Sections
R10950 T15507 T15509 nsubjpass Sections,treated
R10951 T15508 T15509 auxpass were,treated
R10952 T15509 T15509 ROOT treated,treated
R10953 T15510 T15509 prep with,treated
R10954 T15511 T15512 nummod 10,%
R10955 T15512 T15515 compound %,albumin
R10956 T15513 T15514 amod bovine,serum
R10957 T15514 T15515 compound serum,albumin
R10958 T15515 T15510 pobj albumin,with
R10959 T15516 T15515 prep in,albumin
R10960 T15517 T15516 pobj PBS,in
R10961 T15518 T15509 prep for,treated
R10962 T15519 T15520 nummod 1,h
R10963 T15520 T15518 pobj h,for
R10964 T15521 T15520 prep at,h
R10965 T15522 T15523 compound room,temperature
R10966 T15523 T15521 pobj temperature,at
R10967 T15524 T15520 punct ",",h
R10968 T15525 T15526 compound incubated,overnight
R10969 T15526 T15608 dep overnight,conjugated
R10970 T15527 T15526 prep at,overnight
R10971 T15528 T15529 nummod 4,°
R10972 T15529 T15527 pobj °,at
R10973 T15530 T15526 appos C,overnight
R10974 T15531 T15530 prep with,C
R10975 T15532 T15536 nummod p50,250
R10976 T15533 T15534 punct (,1
R10977 T15534 T15536 nummod 1,250
R10978 T15535 T15536 nummod ∶,250
R10979 T15536 T15531 pobj 250,with
R10980 T15537 T15600 punct ",",antibodies
R10981 T15538 T15539 compound Santa,Cruz
R10982 T15539 T15540 compound Cruz,Biotechnology
R10983 T15540 T15600 nmod Biotechnology,antibodies
R10984 T15541 T15540 punct ",",Biotechnology
R10985 T15542 T15543 compound Santa,Cruz
R10986 T15543 T15540 conj Cruz,Biotechnology
R10987 T15544 T15543 punct ",",Cruz
R10988 T15545 T15543 conj CA,Cruz
R10989 T15546 T15540 punct ),Biotechnology
R10990 T15547 T15540 punct ",",Biotechnology
R10991 T15548 T15540 appos p65,Biotechnology
R10992 T15549 T15548 punct (,p65
R10993 T15550 T15552 nummod 1,250
R10994 T15551 T15552 nummod ∶,250
R10995 T15552 T15548 appos 250,p65
R10996 T15553 T15548 punct ",",p65
R10997 T15554 T15556 compound Santa,Biotechnology
R10998 T15555 T15556 compound Cruz,Biotechnology
R10999 T15556 T15548 conj Biotechnology,p65
R11000 T15557 T15556 punct ",",Biotechnology
R11001 T15558 T15559 compound Santa,Cruz
R11002 T15559 T15556 conj Cruz,Biotechnology
R11003 T15560 T15559 punct ",",Cruz
R11004 T15561 T15559 conj CA,Cruz
R11005 T15562 T15556 punct ),Biotechnology
R11006 T15563 T15556 punct ",",Biotechnology
R11007 T15564 T15556 conj Bax,Biotechnology
R11008 T15565 T15566 punct (,1
R11009 T15566 T15569 nummod 1,dilution
R11010 T15567 T15569 nmod ∶,dilution
R11011 T15568 T15569 nummod 200,dilution
R11012 T15569 T15540 appos dilution,Biotechnology
R11013 T15570 T15540 punct ),Biotechnology
R11014 T15571 T15540 punct ",",Biotechnology
R11015 T15572 T15573 nmod cleaved,caspase-3
R11016 T15573 T15540 appos caspase-3,Biotechnology
R11017 T15574 T15577 punct (,100
R11018 T15575 T15577 nummod 1,100
R11019 T15576 T15577 nummod ∶,100
R11020 T15577 T15573 appos 100,caspase-3
R11021 T15578 T15573 punct ),caspase-3
R11022 T15579 T15540 punct ",",Biotechnology
R11023 T15580 T15540 appos CD8,Biotechnology
R11024 T15581 T15582 punct (,1
R11025 T15582 T15584 nummod 1,10
R11026 T15583 T15584 nummod ∶,10
R11027 T15584 T15540 appos 10,Biotechnology
R11028 T15585 T15540 punct ),Biotechnology
R11029 T15586 T15540 punct ",",Biotechnology
R11030 T15587 T15540 appos CD57,Biotechnology
R11031 T15588 T15589 punct (,1
R11032 T15589 T15591 nummod 1,50
R11033 T15590 T15591 nummod ∶,50
R11034 T15591 T15587 appos 50,CD57
R11035 T15592 T15587 punct ),CD57
R11036 T15593 T15587 cc and,CD57
R11037 T15594 T15540 appos IL-1Ra,Biotechnology
R11038 T15595 T15596 punct (,1
R11039 T15596 T15598 nummod 1,500
R11040 T15597 T15598 nummod ∶,500
R11041 T15598 T15540 appos 500,Biotechnology
R11042 T15599 T15600 punct ),antibodies
R11043 T15600 T15608 nsubj antibodies,conjugated
R11044 T15601 T15600 punct ",",antibodies
R11045 T15602 T15600 acl followed,antibodies
R11046 T15603 T15602 agent by,followed
R11047 T15604 T15603 pobj incubation,by
R11048 T15605 T15602 prep in,followed
R11049 T15606 T15607 compound anti-mouse,IgG
R11050 T15607 T15605 pobj IgG,in
R11051 T15608 T15509 advcl conjugated,treated
R11052 T15609 T15608 prep with,conjugated
R11053 T15610 T15616 nmod Alexa,dilution
R11054 T15611 T15610 nummod 488,Alexa
R11055 T15612 T15613 punct (,1
R11056 T15613 T15616 nummod 1,dilution
R11057 T15614 T15616 nmod ∶,dilution
R11058 T15615 T15616 nummod 100,dilution
R11059 T15616 T15609 pobj dilution,with
R11060 T15617 T15616 punct ",",dilution
R11061 T15618 T15619 compound Molecular,Probes
R11062 T15619 T15616 appos Probes,dilution
R11063 T15620 T15619 punct ",",Probes
R11064 T15621 T15630 preconj Eugene,conjugated
R11065 T15622 T15621 punct ",",Eugene
R11066 T15623 T15621 conj OR,Eugene
R11067 T15624 T15623 punct ",",OR
R11068 T15625 T15623 npadvmod USA,OR
R11069 T15626 T15623 punct ),OR
R11070 T15627 T15623 cc and,OR
R11071 T15628 T15629 compound anti-rabbit,IgG
R11072 T15629 T15630 compound IgG,conjugated
R11073 T15630 T15608 conj conjugated,conjugated
R11074 T15631 T15630 prep with,conjugated
R11075 T15632 T15638 nmod Alexa,dilution
R11076 T15633 T15632 nummod 568,Alexa
R11077 T15634 T15635 punct (,1
R11078 T15635 T15638 nummod 1,dilution
R11079 T15636 T15638 nmod ∶,dilution
R11080 T15637 T15638 nummod 100,dilution
R11081 T15638 T15631 pobj dilution,with
R11082 T15639 T15638 punct ",",dilution
R11083 T15640 T15641 compound Molecular,Probes
R11084 T15641 T15638 appos Probes,dilution
R11085 T15642 T15638 punct ),dilution
R11086 T15643 T15638 prep for,dilution
R11087 T15644 T15645 nummod 40,min
R11088 T15645 T15643 pobj min,for
R11089 T15646 T15645 prep at,min
R11090 T15647 T15648 compound room,temperature
R11091 T15648 T15646 pobj temperature,at
R11092 T15649 T15509 punct .,treated
R11093 T15650 T15655 advmod Finally,rinsed
R11094 T15651 T15655 punct ",",rinsed
R11095 T15652 T15653 det the,sections
R11096 T15653 T15655 nsubjpass sections,rinsed
R11097 T15654 T15655 auxpass were,rinsed
R11098 T15655 T15655 ROOT rinsed,rinsed
R11099 T15656 T15655 punct ",",rinsed
R11100 T15657 T15655 conj mounted,rinsed
R11101 T15658 T15657 prep on,mounted
R11102 T15659 T15658 pobj slides,on
R11103 T15660 T15657 punct ",",mounted
R11104 T15661 T15657 cc and,mounted
R11105 T15662 T15657 conj cover-slipped,mounted
R11106 T15663 T15662 prep for,cover-slipped
R11107 T15664 T15665 compound fluorescence,microscopy
R11108 T15665 T15663 pobj microscopy,for
R11109 T15666 T15665 cc and,microscopy
R11110 T15667 T15665 conj photography,microscopy
R11111 T15668 T15657 advcl using,mounted
R11112 T15669 T15670 compound ApoTome,microscopy
R11113 T15670 T15668 dobj microscopy,using
R11114 T15671 T15670 punct (,microscopy
R11115 T15672 T15673 compound Carl,Zeiss
R11116 T15673 T15670 appos Zeiss,microscopy
R11117 T15674 T15673 punct ",",Zeiss
R11118 T15675 T15673 conj Thornwood,Zeiss
R11119 T15676 T15675 punct ",",Thornwood
R11120 T15677 T15675 conj NY,Thornwood
R11121 T15678 T15677 punct ",",NY
R11122 T15679 T15677 conj USA,NY
R11123 T15680 T15670 punct ),microscopy
R11124 T15681 T15655 punct .,rinsed
R11353 T15919 T15923 compound Gel,A
R11354 T15920 T15923 compound Electromobility,A
R11355 T15921 T15922 compound Shift,Assay
R11356 T15922 T15923 compound Assay,A
R11357 T15923 T15932 nsubjpass A,performed
R11358 T15924 T15927 nmod gel,assay
R11359 T15925 T15927 compound electromobility,assay
R11360 T15926 T15927 compound shift,assay
R11361 T15927 T15927 ROOT assay,assay
R11362 T15928 T15927 punct (,assay
R11363 T15929 T15927 appos EMSA,assay
R11364 T15930 T15927 punct ),assay
R11365 T15931 T15932 auxpass was,performed
R11366 T15932 T15932 ROOT performed,performed
R11367 T15933 T15932 prep according,performed
R11368 T15934 T15933 prep to,according
R11369 T15935 T15936 det the,manufacturer
R11370 T15936 T15937 poss manufacturer,recommendations
R11371 T15937 T15934 pobj recommendations,to
R11372 T15938 T15932 punct (,performed
R11373 T15939 T15939 ROOT Promega,Promega
R11374 T15940 T15939 punct ",",Promega
R11375 T15941 T15939 conj Madison,Promega
R11376 T15942 T15941 punct ",",Madison
R11377 T15943 T15941 conj WI,Madison
R11378 T15944 T15939 punct ),Promega
R11379 T15945 T15932 punct .,performed
R11380 T15946 T15948 det The,tissues
R11381 T15947 T15948 compound tumor,tissues
R11382 T15948 T15949 nsubj tissues,were
R11383 T15949 T15949 ROOT were,were
R11384 T15950 T15951 advmod briefly,homogenized
R11385 T15951 T15949 acomp homogenized,were
R11386 T15952 T15951 prep in,homogenized
R11387 T15953 T15954 nummod 200,µl
R11388 T15954 T15952 pobj µl,in
R11389 T15955 T15954 prep of,µl
R11390 T15956 T15957 compound solution,A
R11391 T15957 T15987 det A,incubated
R11392 T15958 T15965 punct (,]
R11393 T15959 T15965 nummod 10,]
R11394 T15960 T15963 compound mM,pH
R11395 T15961 T15963 compound HEPES,pH
R11396 T15962 T15963 compound [,pH
R11397 T15963 T15965 nmod pH,]
R11398 T15964 T15965 nummod 7.9,]
R11399 T15965 T15969 nmod ],MgCl2
R11400 T15966 T15969 punct ",",MgCl2
R11401 T15967 T15969 nummod 1.5,MgCl2
R11402 T15968 T15969 compound mM,MgCl2
R11403 T15969 T15987 dep MgCl2,incubated
R11404 T15970 T15969 punct ",",MgCl2
R11405 T15971 T15973 nummod 10,KCl
R11406 T15972 T15973 compound mM,KCl
R11407 T15973 T15969 conj KCl,MgCl2
R11408 T15974 T15973 punct ",",KCl
R11409 T15975 T15977 nummod 0.5,dithiothreitol
R11410 T15976 T15977 compound mM,dithiothreitol
R11411 T15977 T15973 appos dithiothreitol,KCl
R11412 T15978 T15977 punct ",",dithiothreitol
R11413 T15979 T15981 nummod 0.2,phenylmethylsulfonylfluoride
R11414 T15980 T15981 compound mM,phenylmethylsulfonylfluoride
R11415 T15981 T15977 appos phenylmethylsulfonylfluoride,dithiothreitol
R11416 T15982 T15977 punct ),dithiothreitol
R11417 T15983 T15973 punct ",",KCl
R11418 T15984 T15969 conj vortexed,MgCl2
R11419 T15985 T15984 advmod vigorously,vortexed
R11420 T15986 T15984 punct ",",vortexed
R11421 T15987 T15987 ROOT incubated,incubated
R11422 T15988 T15987 prep on,incubated
R11423 T15989 T15988 pobj ice,on
R11424 T15990 T15987 prep for,incubated
R11425 T15991 T15992 nummod 10,min
R11426 T15992 T15990 pobj min,for
R11427 T15993 T15987 punct ",",incubated
R11428 T15994 T15987 cc and,incubated
R11429 T15995 T15996 advmod then,centrifuged
R11430 T15996 T15987 conj centrifuged,incubated
R11431 T15997 T15996 prep at,centrifuged
R11432 T15998 T15999 nummod 15000,rpm
R11433 T15999 T15997 pobj rpm,at
R11434 T16000 T15996 prep for,centrifuged
R11435 T16001 T16002 nummod 15,min
R11436 T16002 T16000 pobj min,for
R11437 T16003 T15987 punct .,incubated
R11438 T16004 T16006 det The,nuclei
R11439 T16005 T16006 amod pelleted,nuclei
R11440 T16006 T16008 nsubjpass nuclei,resuspended
R11441 T16007 T16008 auxpass were,resuspended
R11442 T16008 T16008 ROOT resuspended,resuspended
R11443 T16009 T16008 prep in,resuspended
R11444 T16010 T16009 pobj solution,in
R11445 T16011 T16008 npadvmod C,resuspended
R11446 T16012 T16015 punct (,supplemented
R11447 T16013 T16014 compound solution,A
R11448 T16014 T16015 nsubj A,supplemented
R11449 T16015 T16011 parataxis supplemented,C
R11450 T16016 T16015 prep with,supplemented
R11451 T16017 T16019 nummod 420,NaCl
R11452 T16018 T16019 compound mM,NaCl
R11453 T16019 T16016 pobj NaCl,with
R11454 T16020 T16019 cc and,NaCl
R11455 T16021 T16022 nummod 20,%
R11456 T16022 T16023 compound %,glycerol
R11457 T16023 T16019 conj glycerol,NaCl
R11458 T16024 T16015 punct ),supplemented
R11459 T16025 T16011 punct ",",C
R11460 T16026 T16011 cc and,C
R11461 T16027 T16011 conj incubated,C
R11462 T16028 T16027 prep on,incubated
R11463 T16029 T16028 pobj ice,on
R11464 T16030 T16027 prep for,incubated
R11465 T16031 T16032 nummod 20,min
R11466 T16032 T16030 pobj min,for
R11467 T16033 T16008 punct .,resuspended
R11468 T16034 T16036 det The,pellet
R11469 T16035 T16036 amod resuspended,pellet
R11470 T16036 T16038 nsubjpass pellet,centrifuged
R11471 T16037 T16038 auxpass was,centrifuged
R11472 T16038 T16038 ROOT centrifuged,centrifuged
R11473 T16039 T16038 prep at,centrifuged
R11474 T16040 T16041 nummod 15000,rpm
R11475 T16041 T16039 pobj rpm,at
R11476 T16042 T16038 prep for,centrifuged
R11477 T16043 T16044 nummod 15,min
R11478 T16044 T16042 pobj min,for
R11479 T16045 T16038 punct ",",centrifuged
R11480 T16046 T16038 cc and,centrifuged
R11481 T16047 T16050 det the,extracts
R11482 T16048 T16050 amod resulting,extracts
R11483 T16049 T16050 amod nuclear,extracts
R11484 T16050 T16053 nsubjpass extracts,collected
R11485 T16051 T16050 amod supernatant,extracts
R11486 T16052 T16053 auxpass were,collected
R11487 T16053 T16038 conj collected,centrifuged
R11488 T16054 T16053 prep in,collected
R11489 T16055 T16058 det a,tube
R11490 T16056 T16058 amod chilled,tube
R11491 T16057 T16058 compound Eppendorf,tube
R11492 T16058 T16054 pobj tube,in
R11493 T16059 T16053 punct .,collected
R11494 T16060 T16061 compound Consensus,oligonucleotides
R11495 T16061 T16064 nsubj oligonucleotides,using
R11496 T16062 T16064 aux were,using
R11497 T16063 T16064 advmod end-labeled,using
R11498 T16064 T16064 ROOT using,using
R11499 T16065 T16067 nummod T4,kinase
R11500 T16066 T16067 compound polynucleotide,kinase
R11501 T16067 T16064 dobj kinase,using
R11502 T16068 T16067 cc and,kinase
R11503 T16069 T16073 compound [,ATP
R11504 T16070 T16073 compound P32,ATP
R11505 T16071 T16073 compound ],ATP
R11506 T16072 T16073 punct -,ATP
R11507 T16073 T16067 conj ATP,kinase
R11508 T16074 T16073 prep for,ATP
R11509 T16075 T16076 nummod 10,min
R11510 T16076 T16074 pobj min,for
R11511 T16077 T16073 prep at,ATP
R11512 T16078 T16079 nummod 37,°
R11513 T16079 T16077 pobj °,at
R11514 T16080 T16073 npadvmod C,ATP
R11515 T16081 T16064 punct .,using
R11516 T16082 T16085 det The,reactions
R11517 T16083 T16084 compound gel,shift
R11518 T16084 T16085 compound shift,reactions
R11519 T16085 T16087 nsubjpass reactions,assembled
R11520 T16086 T16087 auxpass were,assembled
R11521 T16087 T16087 ROOT assembled,assembled
R11522 T16088 T16087 cc and,assembled
R11523 T16089 T16087 conj incubated,assembled
R11524 T16090 T16089 prep at,incubated
R11525 T16091 T16092 compound room,temperature
R11526 T16092 T16090 pobj temperature,at
R11527 T16093 T16087 punct .,assembled
R11528 T16094 T16103 advmod Subsequently,added
R11529 T16095 T16103 punct ",",added
R11530 T16096 T16097 nummod 1,ml
R11531 T16097 T16101 nmod ml,buffer
R11532 T16098 T16097 prep of,ml
R11533 T16099 T16098 pobj gel,of
R11534 T16100 T16101 compound loading,buffer
R11535 T16101 T16103 nsubjpass buffer,added
R11536 T16102 T16103 auxpass was,added
R11537 T16103 T16103 ROOT added,added
R11538 T16104 T16103 prep to,added
R11539 T16105 T16106 det each,reaction
R11540 T16106 T16104 pobj reaction,to
R11541 T16107 T16103 cc and,added
R11542 T16108 T16103 conj loaded,added
R11543 T16109 T16108 prep onto,loaded
R11544 T16110 T16114 det a,gel
R11545 T16111 T16112 nummod 6,%
R11546 T16112 T16114 nmod %,gel
R11547 T16113 T16114 amod non-denaturating,gel
R11548 T16114 T16109 pobj gel,onto
R11549 T16115 T16103 punct .,added
R11550 T16116 T16117 det The,gel
R11551 T16117 T16119 nsubjpass gel,subjected
R11552 T16118 T16119 auxpass was,subjected
R11553 T16119 T16119 ROOT subjected,subjected
R11554 T16120 T16119 prep to,subjected
R11555 T16121 T16120 pobj electrophoresis,to
R11556 T16122 T16125 mark until,was
R11557 T16123 T16124 det the,dye
R11558 T16124 T16125 nsubj dye,was
R11559 T16125 T16119 advcl was,subjected
R11560 T16126 T16125 attr four-fifths,was
R11561 T16127 T16126 prep of,four-fifths
R11562 T16128 T16129 det the,way
R11563 T16129 T16127 pobj way,of
R11564 T16130 T16129 prep down,way
R11565 T16131 T16132 det the,gel
R11566 T16132 T16130 pobj gel,down
R11567 T16133 T16119 punct .,subjected
R11568 T16134 T16135 det The,gel
R11569 T16135 T16137 nsubjpass gel,dried
R11570 T16136 T16137 auxpass was,dried
R11571 T16137 T16137 ROOT dried,dried
R11572 T16138 T16137 prep for,dried
R11573 T16139 T16140 nummod 1,h
R11574 T16140 T16138 pobj h,for
R11575 T16141 T16137 prep at,dried
R11576 T16142 T16144 nummod 80,C
R11577 T16143 T16144 nummod °,C
R11578 T16144 T16141 pobj C,at
R11579 T16145 T16137 cc and,dried
R11580 T16146 T16137 conj exposed,dried
R11581 T16147 T16146 prep to,exposed
R11582 T16148 T16149 compound film,overnight
R11583 T16149 T16147 pobj overnight,to
R11584 T16150 T16146 prep at,exposed
R11585 T16151 T16152 nummod -70,°
R11586 T16152 T16153 nummod °,C.
R11587 T16153 T16150 pobj C.,at
R11813 T16467 T16470 compound Flow,Lymphocytes
R11814 T16468 T16470 compound Cytometric,Lymphocytes
R11815 T16469 T16470 compound Analysis,Lymphocytes
R11816 T16470 T16472 nsubjpass Lymphocytes,obtained
R11817 T16471 T16472 auxpass were,obtained
R11818 T16472 T16472 ROOT obtained,obtained
R11819 T16473 T16472 prep from,obtained
R11820 T16474 T16477 nmod tumor,tissues
R11821 T16475 T16474 cc and,tumor
R11822 T16476 T16474 conj spleen,tumor
R11823 T16477 T16473 pobj tissues,from
R11824 T16478 T16477 prep for,tissues
R11825 T16479 T16480 compound phenotype,analysis
R11826 T16480 T16478 pobj analysis,for
R11827 T16481 T16472 punct .,obtained
R11828 T16482 T16486 nsubj Spleen,were
R11829 T16483 T16482 cc and,Spleen
R11830 T16484 T16485 compound tumor,lymphocytes
R11831 T16485 T16482 conj lymphocytes,Spleen
R11832 T16486 T16487 auxpass were,isolated
R11833 T16487 T16487 ROOT isolated,isolated
R11834 T16488 T16487 prep from,isolated
R11835 T16489 T16490 amod fresh,spleen
R11836 T16490 T16488 pobj spleen,from
R11837 T16491 T16490 cc and,spleen
R11838 T16492 T16493 compound tumor,biopsies
R11839 T16493 T16490 conj biopsies,spleen
R11840 T16494 T16487 conj obtained,isolated
R11841 T16495 T16494 prep from,obtained
R11842 T16496 T16497 nummod three,mice
R11843 T16497 T16495 pobj mice,from
R11844 T16498 T16497 prep per,mice
R11845 T16499 T16498 pobj group,per
R11846 T16500 T16487 punct .,isolated
R11847 T16501 T16507 nsubjpass Spleen,homogenized
R11848 T16502 T16501 cc and,Spleen
R11849 T16503 T16504 compound tumor,biopsies
R11850 T16504 T16501 conj biopsies,Spleen
R11851 T16505 T16507 auxpass were,homogenized
R11852 T16506 T16507 advmod briefly,homogenized
R11853 T16507 T16524 ccomp homogenized,placed
R11854 T16508 T16507 advmod mechanically,homogenized
R11855 T16509 T16507 prep in,homogenized
R11856 T16510 T16509 pobj PBS,in
R11857 T16511 T16507 punct ",",homogenized
R11858 T16512 T16507 conj filtered,homogenized
R11859 T16513 T16517 punct (,strainer
R11860 T16514 T16517 nummod 100,strainer
R11861 T16515 T16517 compound µm,strainer
R11862 T16516 T16517 compound cell,strainer
R11863 T16517 T16512 appos strainer,filtered
R11864 T16518 T16524 punct ;,placed
R11865 T16519 T16520 compound BD,PharMingen
R11866 T16520 T16524 nsubj PharMingen,placed
R11867 T16521 T16520 punct ),PharMingen
R11868 T16522 T16520 cc and,PharMingen
R11869 T16523 T16524 advmod then,placed
R11870 T16524 T16524 ROOT placed,placed
R11871 T16525 T16524 prep in,placed
R11872 T16526 T16527 compound lysis,buffer
R11873 T16527 T16525 pobj buffer,in
R11874 T16528 T16531 punct (,buffer
R11875 T16529 T16531 compound ACK,buffer
R11876 T16530 T16531 compound lysing,buffer
R11877 T16531 T16527 appos buffer,buffer
R11878 T16532 T16531 punct ",",buffer
R11879 T16533 T16531 appos LONZA,buffer
R11880 T16534 T16531 punct ),buffer
R11881 T16535 T16536 aux to,remove
R11882 T16536 T16524 advcl remove,placed
R11883 T16537 T16539 amod red,cells
R11884 T16538 T16539 compound blood,cells
R11885 T16539 T16536 dobj cells,remove
R11886 T16540 T16524 punct .,placed
R11887 T16541 T16542 compound One,million
R11888 T16542 T16543 nummod million,splenocytes
R11889 T16543 T16545 nsubjpass splenocytes,washed
R11890 T16544 T16545 auxpass were,washed
R11891 T16545 T16545 ROOT washed,washed
R11892 T16546 T16545 advmod once,washed
R11893 T16547 T16545 prep in,washed
R11894 T16548 T16547 pobj PBS,in
R11895 T16549 T16545 advcl containing,washed
R11896 T16550 T16551 nummod 1,%
R11897 T16551 T16554 compound %,albumin
R11898 T16552 T16553 amod bovine,serum
R11899 T16553 T16554 compound serum,albumin
R11900 T16554 T16549 dobj albumin,containing
R11901 T16555 T16556 punct (,BSA
R11902 T16556 T16554 appos BSA,albumin
R11903 T16557 T16556 punct ),BSA
R11904 T16558 T16554 cc and,albumin
R11905 T16559 T16554 conj re-suspended,albumin
R11906 T16560 T16559 prep in,re-suspended
R11907 T16561 T16562 nummod 100,µl
R11908 T16562 T16560 pobj µl,in
R11909 T16563 T16562 prep of,µl
R11910 T16564 T16565 compound PBS/BSA,buffer
R11911 T16565 T16563 pobj buffer,of
R11912 T16566 T16545 punct .,washed
R11913 T16567 T16577 advmod Meanwhile,placed
R11914 T16568 T16577 punct ",",placed
R11915 T16569 T16570 compound one,million
R11916 T16570 T16571 nummod million,cells
R11917 T16571 T16577 nsubjpass cells,placed
R11918 T16572 T16571 acl obtained,cells
R11919 T16573 T16572 prep from,obtained
R11920 T16574 T16575 compound tumor,tissues
R11921 T16575 T16573 pobj tissues,from
R11922 T16576 T16577 auxpass were,placed
R11923 T16577 T16577 ROOT placed,placed
R11924 T16578 T16577 prep in,placed
R11925 T16579 T16580 compound RPMI,medium
R11926 T16580 T16578 pobj medium,in
R11927 T16581 T16577 punct ",",placed
R11928 T16582 T16577 conj incubated,placed
R11929 T16583 T16584 aux to,obtain
R11930 T16584 T16582 advcl obtain,incubated
R11931 T16585 T16586 compound suspension,cell
R11932 T16586 T16584 dobj cell,obtain
R11933 T16587 T16586 prep for,cell
R11934 T16588 T16587 pobj 1hour,for
R11935 T16589 T16584 prep at,obtain
R11936 T16590 T16591 nummod 37,°
R11937 T16591 T16592 nummod °,C
R11938 T16592 T16589 pobj C,at
R11939 T16593 T16592 punct ",",C
R11940 T16594 T16592 amod centrifuged,C
R11941 T16595 T16594 punct (,centrifuged
R11942 T16596 T16597 nummod 1200,rpm
R11943 T16597 T16594 appos rpm,centrifuged
R11944 T16598 T16600 punct ",",min
R11945 T16599 T16600 nummod 3,min
R11946 T16600 T16597 appos min,rpm
R11947 T16601 T16597 punct ),rpm
R11948 T16602 T16594 cc and,centrifuged
R11949 T16603 T16604 advmod then,washed
R11950 T16604 T16594 conj washed,centrifuged
R11951 T16605 T16604 prep in,washed
R11952 T16606 T16605 pobj PBS,in
R11953 T16607 T16577 punct .,placed
R11954 T16608 T16613 advmod Next,incubated
R11955 T16609 T16613 punct ",",incubated
R11956 T16610 T16611 det the,lymphocytes
R11957 T16611 T16613 nsubjpass lymphocytes,incubated
R11958 T16612 T16613 auxpass were,incubated
R11959 T16613 T16613 ROOT incubated,incubated
R11960 T16614 T16613 prep with,incubated
R11961 T16615 T16618 amod various,antibodies
R11962 T16616 T16618 amod conjugated,antibodies
R11963 T16617 T16618 amod monoclonal,antibodies
R11964 T16618 T16614 pobj antibodies,with
R11965 T16619 T16618 punct ",",antibodies
R11966 T16620 T16618 prep including,antibodies
R11967 T16621 T16620 pobj CD4-APC,including
R11968 T16622 T16621 punct ",",CD4-APC
R11969 T16623 T16621 conj CD8-FITC,CD4-APC
R11970 T16624 T16623 cc and,CD8-FITC
R11971 T16625 T16623 conj CD19-PE,CD8-FITC
R11972 T16626 T16613 prep for,incubated
R11973 T16627 T16626 pobj 20min,for
R11974 T16628 T16613 prep at,incubated
R11975 T16629 T16630 nummod 4,°
R11976 T16630 T16631 nummod °,C
R11977 T16631 T16628 pobj C,at
R11978 T16632 T16633 punct ",",washed
R11979 T16633 T16613 dep washed,incubated
R11980 T16634 T16633 advmod twice,washed
R11981 T16635 T16633 prep in,washed
R11982 T16636 T16635 pobj PBS,in
R11983 T16637 T16633 punct ",",washed
R11984 T16638 T16633 cc and,washed
R11985 T16639 T16633 conj re-suspended,washed
R11986 T16640 T16639 prep in,re-suspended
R11987 T16641 T16642 nummod 400,µl
R11988 T16642 T16640 pobj µl,in
R11989 T16643 T16642 prep of,µl
R11990 T16644 T16643 pobj PBS,of
R11991 T16645 T16613 punct .,incubated
R11992 T16646 T16649 det A,analysis
R11993 T16647 T16649 nmod flow,analysis
R11994 T16648 T16649 amod cytometric,analysis
R11995 T16649 T16651 nsubjpass analysis,performed
R11996 T16650 T16651 auxpass was,performed
R11997 T16651 T16651 ROOT performed,performed
R11998 T16652 T16651 prep on,performed
R11999 T16653 T16655 det a,flow
R12000 T16654 T16655 compound FACSAria,flow
R12001 T16655 T16652 pobj flow,on
R12002 T16656 T16651 conj cytometry,performed
R12003 T16657 T16659 punct (,Biosciences
R12004 T16658 T16659 compound BD,Biosciences
R12005 T16659 T16656 appos Biosciences,cytometry
R12006 T16660 T16659 punct ),Biosciences
R12007 T16661 T16656 punct ",",cytometry
R12008 T16662 T16656 cc and,cytometry
R12009 T16663 T16664 det the,data
R12010 T16664 T16666 nsubjpass data,analyzed
R12011 T16665 T16666 auxpass were,analyzed
R12012 T16666 T16656 conj analyzed,cytometry
R12013 T16667 T16666 advcl using,analyzed
R12014 T16668 T16671 det the,software
R12015 T16669 T16671 nmod WinMDI,software
R12016 T16670 T16671 amod statistical,software
R12017 T16671 T16667 dobj software,using
R12018 T16672 T16681 punct (,)
R12019 T16673 T16681 nmod Scripps,)
R12020 T16674 T16673 punct ",",Scripps
R12021 T16675 T16676 compound La,Jolla
R12022 T16676 T16673 conj Jolla,Scripps
R12023 T16677 T16676 punct ",",Jolla
R12024 T16678 T16676 conj CA,Jolla
R12025 T16679 T16678 punct ",",CA
R12026 T16680 T16678 conj USA,CA
R12027 T16681 T16671 punct ),software
R12028 T16682 T16666 punct .,analyzed
R12029 T16683 T16687 amod Forward,parameters
R12030 T16684 T16683 cc and,Forward
R12031 T16685 T16687 compound side,parameters
R12032 T16686 T16687 compound scatter,parameters
R12033 T16687 T16689 nsubjpass parameters,used
R12034 T16688 T16689 auxpass were,used
R12035 T16689 T16689 ROOT used,used
R12036 T16690 T16691 aux to,gate
R12037 T16691 T16689 xcomp gate,used
R12038 T16692 T16691 prep on,gate
R12039 T16693 T16692 pobj lymphocytes,on
R12040 T16694 T16689 punct .,used
R12147 T16842 T16843 compound Protein,Immuno-arrays
R12148 T16843 T16848 nmod Immuno-arrays,tissues
R12149 T16844 T16845 det The,tumor
R12150 T16845 T16848 nmod tumor,tissues
R12151 T16846 T16845 cc and,tumor
R12152 T16847 T16845 conj spleen,tumor
R12153 T16848 T16850 nsubjpass tissues,excised
R12154 T16849 T16850 auxpass were,excised
R12155 T16850 T16850 ROOT excised,excised
R12156 T16851 T16850 cc and,excised
R12157 T16852 T16850 conj homogenized,excised
R12158 T16853 T16852 prep in,homogenized
R12159 T16854 T16853 pobj PBS,in
R12160 T16855 T16852 prep with,homogenized
R12161 T16856 T16858 compound protease,cocktail
R12162 T16857 T16858 compound inhibitor,cocktail
R12163 T16858 T16855 pobj cocktail,with
R12164 T16859 T16860 punct (,Sigma-Aldrich
R12165 T16860 T16858 appos Sigma-Aldrich,cocktail
R12166 T16861 T16860 punct ",",Sigma-Aldrich
R12167 T16862 T16860 appos USA,Sigma-Aldrich
R12168 T16863 T16860 punct ),Sigma-Aldrich
R12169 T16864 T16858 cc and,cocktail
R12170 T16865 T16866 compound Triton,X-100
R12171 T16866 T16858 conj X-100,cocktail
R12172 T16867 T16869 punct (,concentration
R12173 T16868 T16869 amod final,concentration
R12174 T16869 T16866 parataxis concentration,X-100
R12175 T16870 T16871 nummod 1,%
R12176 T16871 T16869 appos %,concentration
R12177 T16872 T16869 punct ),concentration
R12178 T16873 T16850 punct .,excised
R12179 T16874 T16875 det The,samples
R12180 T16875 T16877 nsubjpass samples,frozen
R12181 T16876 T16877 auxpass were,frozen
R12182 T16877 T16877 ROOT frozen,frozen
R12183 T16878 T16877 prep at,frozen
R12184 T16879 T16882 nummod −,C
R12185 T16880 T16881 nummod 70,°
R12186 T16881 T16882 compound °,C
R12187 T16882 T16878 pobj C,at
R12188 T16883 T16877 punct ",",frozen
R12189 T16884 T16877 conj thawed,frozen
R12190 T16885 T16884 punct ",",thawed
R12191 T16886 T16884 cc and,thawed
R12192 T16887 T16884 conj centrifuged,thawed
R12193 T16888 T16887 prep at,centrifuged
R12194 T16889 T16890 nummod "10,000",×
R12195 T16890 T16891 compound ×,g
R12196 T16891 T16888 pobj g,at
R12197 T16892 T16896 mark for,remove
R12198 T16893 T16894 nummod 5,min
R12199 T16894 T16896 nsubj min,remove
R12200 T16895 T16896 aux to,remove
R12201 T16896 T16887 advcl remove,centrifuged
R12202 T16897 T16898 amod cellular,debris
R12203 T16898 T16896 dobj debris,remove
R12204 T16899 T16877 punct .,frozen
R12205 T16900 T16901 det The,tissue
R12206 T16901 T16902 compound tissue,lysates
R12207 T16902 T16904 nsubjpass lysates,performed
R12208 T16903 T16904 auxpass were,performed
R12209 T16904 T16904 ROOT performed,performed
R12210 T16905 T16906 compound protein,assay
R12211 T16906 T16904 dobj assay,performed
R12212 T16907 T16904 prep in,performed
R12213 T16908 T16910 det the,way
R12214 T16909 T16910 amod same,way
R12215 T16910 T16907 pobj way,in
R12216 T16911 T16910 prep as,way
R12217 T16912 T16911 prep for,as
R12218 T16913 T16914 amod western,blotting
R12219 T16914 T16912 pobj blotting,for
R12220 T16915 T16904 punct .,performed
R12221 T16916 T16917 nummod 4.5,mg
R12222 T16917 T16929 nsubjpass mg,used
R12223 T16918 T16917 prep of,mg
R12224 T16919 T16918 pobj proteins,of
R12225 T16920 T16917 punct ",",mg
R12226 T16921 T16917 acl collected,mg
R12227 T16922 T16921 prep from,collected
R12228 T16923 T16924 nummod three,samples
R12229 T16924 T16922 pobj samples,from
R12230 T16925 T16924 prep per,samples
R12231 T16926 T16925 pobj group,per
R12232 T16927 T16929 punct ",",used
R12233 T16928 T16929 auxpass were,used
R12234 T16929 T16929 ROOT used,used
R12235 T16930 T16929 prep for,used
R12236 T16931 T16933 compound Mouse,array
R12237 T16932 T16933 compound cytokine,array
R12238 T16933 T16930 pobj array,for
R12239 T16934 T16929 prep as,used
R12240 T16935 T16936 det the,protocol
R12241 T16936 T16934 pobj protocol,as
R12242 T16937 T16936 acl provided,protocol
R12243 T16938 T16937 agent by,provided
R12244 T16939 T16938 pobj supplier,by
R12245 T16940 T16943 punct (,™
R12246 T16941 T16943 compound Proteome,™
R12247 T16942 T16943 compound Profiler,™
R12248 T16943 T16939 appos ™,supplier
R12249 T16944 T16943 punct ",",™
R12250 T16945 T16946 compound #ARY,006
R12251 T16946 T16943 appos 006,™
R12252 T16947 T16943 punct ",",™
R12253 T16948 T16949 compound R&D,Systems
R12254 T16949 T16943 conj Systems,™
R12255 T16950 T16949 punct ",",Systems
R12256 T16951 T16949 conj USA,Systems
R12257 T16952 T16943 punct ),™
R12258 T16953 T16929 punct .,used
R12337 T17081 T17082 compound Statistical,Analysis
R12338 T17082 T17086 nsubjpass Analysis,analyzed
R12339 T17083 T17084 det The,data
R12340 T17084 T17086 nsubjpass data,analyzed
R12341 T17085 T17086 auxpass were,analyzed
R12342 T17086 T17086 ROOT analyzed,analyzed
R12343 T17087 T17086 advcl using,analyzed
R12344 T17088 T17092 det the,ver
R12345 T17089 T17090 compound GraphPad,Prism
R12346 T17090 T17092 nmod Prism,ver
R12347 T17091 T17090 nummod 4,Prism
R12348 T17092 T17087 dobj ver,using
R12349 T17093 T17086 punct .,analyzed
R12350 T17094 T17095 nummod 4.03,software
R12351 T17095 T17095 ROOT software,software
R12352 T17096 T17098 punct (,Software
R12353 T17097 T17098 compound GraphPad,Software
R12354 T17098 T17095 appos Software,software
R12355 T17099 T17098 punct ",",Software
R12356 T17100 T17101 compound La,Jolla
R12357 T17101 T17098 npadvmod Jolla,Software
R12358 T17102 T17101 punct ",",Jolla
R12359 T17103 T17098 appos CA,Software
R12360 T17104 T17098 punct ),Software
R12361 T17105 T17095 punct .,software
R12362 T17106 T17108 nsubjpass Data,presented
R12363 T17107 T17108 auxpass are,presented
R12364 T17108 T17108 ROOT presented,presented
R12365 T17109 T17108 prep as,presented
R12366 T17110 T17112 amod mean,SD
R12367 T17111 T17112 compound ±,SD
R12368 T17112 T17109 pobj SD,as
R12369 T17113 T17108 punct .,presented
R12370 T17114 T17128 nsubjpass Difference,compared
R12371 T17115 T17114 prep between,Difference
R12372 T17116 T17120 nummod CCR5,mice
R12373 T17117 T17120 nummod −,mice
R12374 T17118 T17120 nmod /,mice
R12375 T17119 T17120 compound −,mice
R12376 T17120 T17115 pobj mice,between
R12377 T17121 T17120 cc and,mice
R12378 T17122 T17120 conj CCR5,mice
R12379 T17123 T17128 amod +,compared
R12380 T17124 T17126 nummod /,mice
R12381 T17125 T17126 nummod +,mice
R12382 T17126 T17128 nsubjpass mice,compared
R12383 T17127 T17128 auxpass were,compared
R12384 T17128 T17128 ROOT compared,compared
R12385 T17129 T17128 advcl using,compared
R12386 T17130 T17131 compound t,test
R12387 T17131 T17129 dobj test,using
R12388 T17132 T17128 punct .,compared
R12389 T17133 T17134 det A,value
R12390 T17134 T17140 nsubjpass value,considered
R12391 T17135 T17134 prep of,value
R12392 T17136 T17137 compound p,<
R12393 T17137 T17138 compound <,0.05
R12394 T17138 T17135 pobj 0.05,of
R12395 T17139 T17140 auxpass was,considered
R12396 T17140 T17140 ROOT considered,considered
R12397 T17141 T17142 aux to,be
R12398 T17142 T17140 xcomp be,considered
R12399 T17143 T17144 advmod statistically,significant
R12400 T17144 T17142 acomp significant,be
R12401 T17145 T17140 punct .,considered
R12402 T17146 T17147 compound Survival,data
R12403 T17147 T17149 nsubjpass data,presented
R12404 T17148 T17149 auxpass were,presented
R12405 T17149 T17149 ROOT presented,presented
R12406 T17150 T17149 agent by,presented
R12407 T17151 T17153 compound Kaplan-Meier,estimates
R12408 T17152 T17153 compound survival,estimates
R12409 T17153 T17150 pobj estimates,by
R12410 T17154 T17149 cc and,presented
R12411 T17155 T17149 conj compared,presented
R12412 T17156 T17155 cc and,compared
R12413 T17157 T17155 conj calculated,compared
R12414 T17158 T17157 agent by,calculated
R12415 T17159 T17163 amod Log-rank,Test
R12416 T17160 T17161 punct (,Mantel-Cox
R12417 T17161 T17159 appos Mantel-Cox,Log-rank
R12418 T17162 T17161 punct ),Mantel-Cox
R12419 T17163 T17158 pobj Test,by
R12420 T17164 T17157 prep in,calculated
R12421 T17165 T17166 compound GraphPad,Prism
R12422 T17166 T17164 pobj Prism,in
R12423 T17167 T17149 punct .,presented
R12576 T17423 T17423 ROOT Inhibition,Inhibition
R12577 T17424 T17423 prep of,Inhibition
R12578 T17425 T17426 compound tumor,development
R12579 T17426 T17424 pobj development,of
R12580 T17427 T17423 prep in,Inhibition
R12581 T17428 T17432 nummod CCR5,mice
R12582 T17429 T17432 nummod −,mice
R12583 T17430 T17432 nmod /,mice
R12584 T17431 T17432 compound −,mice
R12585 T17432 T17427 pobj mice,in
R12586 T17433 T17423 punct .,Inhibition
R12587 T17434 T17438 det A,images
R12588 T17435 T17438 nmod C,images
R12589 T17436 T17438 punct ",",images
R12590 T17437 T17438 compound Tumor,images
R12591 T17438 T17438 ROOT images,images
R12592 T17439 T17438 punct ",",images
R12593 T17440 T17438 conj volumes,images
R12594 T17441 T17440 punct ",",volumes
R12595 T17442 T17440 cc and,volumes
R12596 T17443 T17440 conj weights,volumes
R12597 T17444 T17438 punct .,images
R12598 T17445 T17447 nummod B16,cells
R12599 T17446 T17447 compound melanoma,cells
R12600 T17447 T17455 nsubjpass cells,inoculated
R12601 T17448 T17447 punct (,cells
R12602 T17449 T17447 appos 5,cells
R12603 T17450 T17453 nmod ×,)
R12604 T17451 T17452 nummod 105,cells/mouse
R12605 T17452 T17450 appos cells/mouse,×
R12606 T17453 T17447 punct ),cells
R12607 T17454 T17455 auxpass were,inoculated
R12608 T17455 T17455 ROOT inoculated,inoculated
R12609 T17456 T17455 advmod s.c.,inoculated
R12610 T17457 T17455 prep into,inoculated
R12611 T17458 T17462 nummod CCR5,mice
R12612 T17459 T17462 nummod +,mice
R12613 T17460 T17462 compound /,mice
R12614 T17461 T17462 compound +,mice
R12615 T17462 T17457 pobj mice,into
R12616 T17463 T17462 cc and,mice
R12617 T17464 T17462 conj CCR5,mice
R12618 T17465 T17455 advcl −,inoculated
R12619 T17466 T17468 nummod /,mice
R12620 T17467 T17468 nummod −,mice
R12621 T17468 T17465 dobj mice,−
R12622 T17469 T17468 punct (,mice
R12623 T17470 T17472 advmod n,20
R12624 T17471 T17472 punct =,20
R12625 T17472 T17455 npadvmod 20,inoculated
R12626 T17473 T17455 punct ),inoculated
R12627 T17474 T17455 punct .,inoculated
R12628 T17475 T17476 compound Tumor,volumes
R12629 T17476 T17478 nsubjpass volumes,measured
R12630 T17477 T17478 auxpass were,measured
R12631 T17478 T17478 ROOT measured,measured
R12632 T17479 T17480 det every,day
R12633 T17480 T17478 npadvmod day,measured
R12634 T17481 T17480 cc and,day
R12635 T17482 T17483 compound tumor,weights
R12636 T17483 T17485 nsubjpass weights,measured
R12637 T17484 T17485 auxpass were,measured
R12638 T17485 T17478 conj measured,measured
R12639 T17486 T17485 prep at,measured
R12640 T17487 T17488 compound study,termination
R12641 T17488 T17486 pobj termination,at
R12642 T17489 T17490 punct (,Day
R12643 T17490 T17488 appos Day,termination
R12644 T17491 T17490 nummod 31,Day
R12645 T17492 T17490 punct ),Day
R12646 T17493 T17485 punct .,measured
R12647 T17494 T17496 det The,−
R12648 T17495 T17496 compound CCR5,−
R12649 T17496 T17497 nsubj −,/
R12650 T17497 T17497 ROOT /,/
R12651 T17498 T17499 nummod −,mice
R12652 T17499 T17500 nsubj mice,had
R12653 T17500 T17497 ccomp had,/
R12654 T17501 T17503 det a,reduction
R12655 T17502 T17503 amod significant,reduction
R12656 T17503 T17500 dobj reduction,had
R12657 T17504 T17503 prep in,reduction
R12658 T17505 T17506 compound tumor,growth
R12659 T17506 T17504 pobj growth,in
R12660 T17507 T17506 cc and,growth
R12661 T17508 T17506 conj volume,growth
R12662 T17509 T17510 mark as,compared
R12663 T17510 T17500 advcl compared,had
R12664 T17511 T17510 prep to,compared
R12665 T17512 T17516 nummod CCR5,mice
R12666 T17513 T17516 nummod +,mice
R12667 T17514 T17516 compound /,mice
R12668 T17515 T17516 compound +,mice
R12669 T17516 T17511 pobj mice,to
R12670 T17526 T17497 punct .,/
R12671 T17527 T17528 det The,results
R12672 T17528 T17530 nsubjpass results,expressed
R12673 T17529 T17530 auxpass are,expressed
R12674 T17530 T17530 ROOT expressed,expressed
R12675 T17531 T17530 prep as,expressed
R12676 T17532 T17534 amod mean,SD
R12677 T17533 T17534 compound ±,SD
R12678 T17534 T17531 pobj SD,as
R12679 T17535 T17530 punct .,expressed
R12680 T17536 T17537 nsubj *,indicates
R12681 T17537 T17537 ROOT indicates,indicates
R12682 T17538 T17539 amod significant,difference
R12683 T17539 T17537 dobj difference,indicates
R12684 T17540 T17537 prep from,indicates
R12685 T17541 T17545 nummod CCR5,mice
R12686 T17542 T17545 nummod +,mice
R12687 T17543 T17545 compound /,mice
R12688 T17544 T17545 compound +,mice
R12689 T17545 T17540 pobj mice,from
R12690 T17546 T17545 punct (,mice
R12691 T17547 T17545 appos P,mice
R12692 T17548 T17549 compound <,0.05
R12693 T17549 T17547 nummod 0.05,P
R12694 T17550 T17545 punct ),mice
R12695 T17551 T17537 punct .,indicates
R12696 T17552 T17557 advmod D,/
R12697 T17553 T17557 punct ",",/
R12698 T17554 T17556 det The,−
R12699 T17555 T17556 compound CCR5,−
R12700 T17556 T17557 nsubj −,/
R12701 T17557 T17557 ROOT /,/
R12702 T17558 T17559 nummod −,mice
R12703 T17559 T17560 nsubj mice,demonstrated
R12704 T17560 T17557 ccomp demonstrated,/
R12705 T17561 T17562 advmod significantly,higher
R12706 T17562 T17564 amod higher,rates
R12707 T17563 T17564 compound survival,rates
R12708 T17564 T17560 dobj rates,demonstrated
R12709 T17565 T17560 prep compared,demonstrated
R12710 T17566 T17565 prep to,compared
R12711 T17567 T17571 nummod CCR5,mice
R12712 T17568 T17571 nummod +,mice
R12713 T17569 T17571 compound /,mice
R12714 T17570 T17571 compound +,mice
R12715 T17571 T17566 pobj mice,to
R12716 T17572 T17571 punct (,mice
R12717 T17573 T17571 prep by,mice
R12718 T17574 T17575 compound Log-rank,Test
R12719 T17575 T17573 pobj Test,by
R12720 T17576 T17571 punct ),mice
R12721 T17577 T17557 punct .,/
R12722 T17578 T17579 compound E.,Tumor
R12723 T17579 T17580 compound Tumor,sections
R12724 T17580 T17582 nsubjpass sections,analyzed
R12725 T17581 T17582 auxpass were,analyzed
R12726 T17582 T17582 ROOT analyzed,analyzed
R12727 T17583 T17582 agent by,analyzed
R12728 T17584 T17583 pobj H&E,by
R12729 T17585 T17582 xcomp stain,analyzed
R12730 T17586 T17585 cc and,stain
R12731 T17587 T17585 conj expression,stain
R12732 T17588 T17587 prep of,expression
R12733 T17589 T17588 pobj proliferating,of
R12734 T17590 T17592 compound cell,antigen
R12735 T17591 T17592 amod nuclear,antigen
R12736 T17592 T17589 dobj antigen,proliferating
R12737 T17593 T17592 punct (,antigen
R12738 T17594 T17592 appos PCNA,antigen
R12739 T17595 T17592 punct ),antigen
R12740 T17596 T17589 prep by,proliferating
R12741 T17597 T17596 pobj immunohistochemistry,by
R12742 T17598 T17582 punct .,analyzed
R12743 T17599 T17600 nsubj Data,are
R12744 T17600 T17600 ROOT are,are
R12745 T17601 T17600 ccomp means,are
R12746 T17602 T17601 dobj ±,means
R12747 T17603 T17602 appos S.D.,±
R12748 T17604 T17603 prep of,S.D.
R12749 T17605 T17641 nummod four,animals
R12752 T17640 T17641 amod experimental,animals
R12753 T17641 T17604 pobj animals,of
R12754 T17642 T17600 punct .,are
R12755 T17643 T17644 nsubj *,indicates
R12756 T17644 T17644 ROOT indicates,indicates
R12757 T17645 T17646 amod significant,difference
R12758 T17646 T17644 dobj difference,indicates
R12759 T17647 T17646 prep from,difference
R12760 T17648 T17652 nummod CCR5,mice
R12761 T17649 T17652 nummod +,mice
R12762 T17650 T17652 compound /,mice
R12763 T17651 T17652 compound +,mice
R12764 T17652 T17647 pobj mice,from
R12765 T17653 T17652 punct (,mice
R12766 T17654 T17657 nmod P,)
R12767 T17655 T17656 compound <,0.05
R12768 T17656 T17654 nummod 0.05,P
R12769 T17657 T17652 punct ),mice
R12770 T17658 T17644 punct .,indicates
R12771 T17659 T17660 compound Scale,bar
R12772 T17660 T17661 nsubj bar,indicates
R12773 T17661 T17661 ROOT indicates,indicates
R12774 T17662 T17663 nummod 50,m.
R12775 T17663 T17661 dobj m.,indicates
R12903 T17906 T17906 ROOT Decrease,Decrease
R12904 T17907 T17906 prep of,Decrease
R12905 T17908 T17909 amod NF-κB,Activity
R12906 T17909 T17907 pobj Activity,of
R12907 T17910 T17906 prep in,Decrease
R12908 T17911 T17912 compound Tumor,Tissue
R12909 T17912 T17910 pobj Tissue,in
R12910 T17913 T17912 prep of,Tissue
R12911 T17914 T17918 nummod CCR5,Mice
R12912 T17915 T17918 nummod −,Mice
R12913 T17916 T17918 compound /,Mice
R12914 T17917 T17918 compound −,Mice
R12915 T17918 T17913 pobj Mice,of
R12916 T17919 T17906 punct .,Decrease
R12917 T17920 T17929 nsubjpass A,determined
R12918 T17921 T17920 punct ",",A
R12919 T17922 T17925 det The,activity
R12920 T17923 T17925 nmod DNA,activity
R12921 T17924 T17925 amod binding,activity
R12922 T17925 T17929 nsubjpass activity,determined
R12923 T17926 T17925 prep of,activity
R12924 T17927 T17926 pobj NF-κB,of
R12925 T17928 T17929 auxpass was,determined
R12926 T17929 T17929 ROOT determined,determined
R12927 T17930 T17929 prep in,determined
R12928 T17931 T17933 det the,extracts
R12929 T17932 T17933 amod nuclear,extracts
R12930 T17933 T17930 pobj extracts,in
R12931 T17934 T17933 prep of,extracts
R12932 T17935 T17937 det the,−
R12933 T17936 T17937 compound CCR5,−
R12934 T17937 T17934 pobj −,of
R12935 T17938 T17929 conj /,determined
R12936 T17939 T17940 nummod −,mice
R12937 T17940 T17938 dobj mice,/
R12938 T17941 T17940 cc and,mice
R12939 T17942 T17940 conj CCR5,mice
R12940 T17943 T17948 nmod +,tissues
R12941 T17944 T17948 nummod /,tissues
R12942 T17945 T17946 nummod +,mice
R12943 T17946 T17948 compound mice,tissues
R12944 T17947 T17948 compound tumor,tissues
R12945 T17948 T17951 nsubj tissues,described
R12946 T17949 T17948 prep by,tissues
R12947 T17950 T17949 pobj EMSA,by
R12948 T17951 T17938 conj described,/
R12949 T17952 T17951 prep in,described
R12950 T17953 T17952 pobj material,in
R12951 T17954 T17953 cc and,material
R12952 T17955 T17953 conj methods,material
R12953 T17956 T17951 punct .,described
R12954 T17957 T17957 ROOT B,B
R12955 T17958 T17957 punct ",",B
R12956 T17959 T17957 appos Expression,B
R12957 T17960 T17959 prep of,Expression
R12958 T17961 T17960 pobj p50,of
R12959 T17962 T17961 cc and,p50
R12960 T17963 T17964 nummod p65,phosphorylation
R12961 T17964 T17961 conj phosphorylation,p50
R12962 T17965 T17964 prep in,phosphorylation
R12963 T17966 T17967 amod nuclear,extracts
R12964 T17967 T17965 pobj extracts,in
R12965 T17968 T17967 punct (,extracts
R12966 T17969 T17967 appos NE,extracts
R12967 T17970 T17967 punct ),extracts
R12968 T17971 T17964 punct ",",phosphorylation
R12969 T17972 T17964 cc and,phosphorylation
R12970 T17973 T17964 conj IκB,phosphorylation
R12971 T17974 T17973 cc and,IκB
R12972 T17975 T17976 compound IκB,phosphorylation
R12973 T17976 T17973 conj phosphorylation,IκB
R12974 T17977 T17976 prep in,phosphorylation
R12975 T17978 T17979 det the,cytosol
R12976 T17979 T17977 pobj cytosol,in
R12977 T17980 T17983 punct (,determined
R12978 T17981 T17983 dep CE,determined
R12979 T17982 T17983 punct ),determined
R12980 T17983 T17957 acl determined,B
R12981 T17984 T17983 agent by,determined
R12982 T17985 T17986 amod Western,blotting
R12983 T17986 T17984 pobj blotting,by
R12984 T17987 T17957 punct .,B
R12985 T17988 T17994 nsubj C,confirmed
R12986 T17989 T17988 punct ",",C
R12987 T17990 T17991 compound Immunolfluorescence,analysis
R12988 T17991 T17988 appos analysis,C
R12989 T17992 T17991 prep of,analysis
R12990 T17993 T17992 pobj p50,of
R12991 T17994 T17994 ROOT confirmed,confirmed
R12992 T17995 T18004 mark that,decreased
R12993 T17996 T17997 det the,intensities
R12994 T17997 T18004 nsubjpass intensities,decreased
R12995 T17998 T17997 prep of,intensities
R12996 T17999 T18000 amod nuclear,staining
R12997 T18000 T17998 pobj staining,of
R12998 T18001 T17997 prep for,intensities
R12999 T18002 T18001 pobj p50,for
R13000 T18003 T18004 auxpass were,decreased
R13001 T18004 T17994 ccomp decreased,confirmed
R13002 T18005 T18004 prep in,decreased
R13003 T18006 T18008 det the,tissues
R13004 T18007 T18008 compound tumor,tissues
R13005 T18008 T18005 pobj tissues,in
R13006 T18009 T18008 prep of,tissues
R13007 T18010 T18014 nummod CCR5,mice
R13008 T18011 T18014 nummod −,mice
R13009 T18012 T18014 nmod /,mice
R13010 T18013 T18014 compound −,mice
R13011 T18014 T18009 pobj mice,of
R13012 T18015 T17994 punct .,confirmed
R13013 T18016 T18017 nsubj Data,are
R13014 T18017 T18017 ROOT are,are
R13015 T18018 T18017 ccomp means,are
R13016 T18019 T18020 compound ±,S.D.
R13017 T18020 T18018 dobj S.D.,means
R13018 T18021 T18020 prep of,S.D.
R13019 T18022 T18024 nummod four,animals
R13020 T18023 T18024 amod experimental,animals
R13021 T18024 T18021 pobj animals,of
R13022 T18025 T18017 punct .,are
R13023 T18026 T18027 nsubj *,indicates
R13024 T18027 T18027 ROOT indicates,indicates
R13025 T18028 T18029 amod significant,difference
R13026 T18029 T18027 dobj difference,indicates
R13027 T18030 T18029 prep from,difference
R13028 T18031 T18035 nummod CCR5,mice
R13029 T18032 T18035 nummod +,mice
R13030 T18033 T18035 compound /,mice
R13031 T18034 T18035 compound +,mice
R13032 T18035 T18030 pobj mice,from
R13033 T18036 T18035 punct (,mice
R13034 T18037 T18040 dobj p,)
R13035 T18038 T18039 compound <,0.05
R13036 T18039 T18037 nummod 0.05,p
R13037 T18040 T18035 punct ),mice
R13038 T18041 T18027 punct .,indicates
R13039 T18042 T18043 compound Scale,bar
R13040 T18043 T18044 nsubj bar,indicates
R13041 T18044 T18044 ROOT indicates,indicates
R13042 T18045 T18046 nummod 50,µm
R13043 T18046 T18044 dobj µm,indicates
R13044 T18047 T18044 punct .,indicates
R13304 T18556 T18556 ROOT Induction,Induction
R13305 T18557 T18556 prep of,Induction
R13306 T18558 T18560 amod Apoptotic,Death
R13307 T18559 T18560 compound Cell,Death
R13308 T18560 T18557 pobj Death,of
R13309 T18561 T18556 prep in,Induction
R13310 T18562 T18563 compound tumor,tissues
R13311 T18563 T18561 pobj tissues,in
R13312 T18564 T18563 prep of,tissues
R13313 T18565 T18569 nummod CCR5,mice
R13314 T18566 T18569 nummod −,mice
R13315 T18567 T18569 nmod /,mice
R13316 T18568 T18569 compound −,mice
R13317 T18569 T18564 pobj mice,of
R13318 T18570 T18556 punct .,Induction
R13319 T18571 T18579 nsubjpass A,examined
R13320 T18572 T18579 punct ",",examined
R13321 T18573 T18574 amod Apoptotic,cells
R13322 T18574 T18579 nsubjpass cells,examined
R13323 T18575 T18574 prep in,cells
R13324 T18576 T18577 compound tumor,sections
R13325 T18577 T18575 pobj sections,in
R13326 T18578 T18579 auxpass were,examined
R13327 T18579 T18579 ROOT examined,examined
R13328 T18580 T18579 agent by,examined
R13329 T18581 T18582 compound fluorescence,microscopy
R13330 T18582 T18580 pobj microscopy,by
R13331 T18583 T18579 prep after,examined
R13332 T18584 T18583 pobj DAPI,after
R13333 T18585 T18584 cc and,DAPI
R13334 T18586 T18584 conj TUNEL,DAPI
R13335 T18587 T18579 advcl staining,examined
R13336 T18588 T18589 mark as,described
R13337 T18589 T18587 advcl described,staining
R13338 T18590 T18589 prep in,described
R13339 T18591 T18590 pobj material,in
R13340 T18592 T18591 cc and,material
R13341 T18593 T18591 conj methods,material
R13342 T18594 T18579 punct .,examined
R13343 T18595 T18597 det The,index
R13344 T18596 T18597 amod apoptotic,index
R13345 T18597 T18599 nsubjpass index,determined
R13346 T18598 T18599 auxpass was,determined
R13347 T18599 T18599 ROOT determined,determined
R13348 T18600 T18599 prep as,determined
R13349 T18601 T18602 det the,number
R13350 T18602 T18600 pobj number,as
R13351 T18603 T18602 prep of,number
R13352 T18604 T18607 amod DAPI-stained,cells
R13353 T18605 T18607 punct ",",cells
R13354 T18606 T18607 amod TUNEL-positive,cells
R13355 T18607 T18603 pobj cells,of
R13356 T18608 T18610 nsubjpass that,counted
R13357 T18609 T18610 auxpass were,counted
R13358 T18610 T18607 relcl counted,cells
R13359 T18611 T18599 punct .,determined
R13360 T18612 T18613 nsubj Values,are
R13361 T18613 T18613 ROOT are,are
R13362 T18614 T18617 det the,S.D.
R13363 T18615 T18617 amod mean,S.D.
R13364 T18616 T18617 compound ±,S.D.
R13365 T18617 T18613 attr S.D.,are
R13366 T18618 T18617 prep of,S.D.
R13367 T18619 T18621 nummod four,animals
R13368 T18620 T18621 amod experimental,animals
R13369 T18621 T18618 pobj animals,of
R13370 T18622 T18613 punct .,are
R13371 T18623 T18624 nsubj *,indicates
R13372 T18624 T18624 ROOT indicates,indicates
R13373 T18625 T18626 advmod statistically,significant
R13374 T18626 T18627 amod significant,differences
R13375 T18627 T18624 dobj differences,indicates
R13376 T18628 T18627 prep from,differences
R13377 T18629 T18633 nummod CCR5,mice
R13378 T18630 T18633 nummod +,mice
R13379 T18631 T18633 compound /,mice
R13380 T18632 T18633 compound +,mice
R13381 T18633 T18628 pobj mice,from
R13382 T18634 T18624 punct .,indicates
R13383 T18635 T18636 compound Scale,bar
R13384 T18636 T18637 nsubj bar,indicates
R13385 T18637 T18637 ROOT indicates,indicates
R13386 T18638 T18639 nummod 50,µm
R13387 T18639 T18637 dobj µm,indicates
R13388 T18640 T18637 punct .,indicates
R13389 T18641 T18657 nsubjpass B,detected
R13390 T18642 T18641 cc and,B
R13391 T18643 T18641 conj C,B
R13392 T18644 T18643 punct ",",C
R13393 T18645 T18646 compound Apoptotic,protein
R13394 T18646 T18641 conj protein,B
R13395 T18647 T18648 punct (,cleaved
R13396 T18648 T18646 appos cleaved,protein
R13397 T18649 T18648 oprd caspase-3,cleaved
R13398 T18650 T18648 cc and,cleaved
R13399 T18651 T18648 conj Bax,cleaved
R13400 T18652 T18648 punct ),cleaved
R13401 T18653 T18646 prep in,protein
R13402 T18654 T18655 compound tumor,sections
R13403 T18655 T18653 pobj sections,in
R13404 T18656 T18657 auxpass were,detected
R13405 T18657 T18657 ROOT detected,detected
R13406 T18658 T18657 agent by,detected
R13407 T18659 T18660 compound immunofluorescence,assay
R13408 T18660 T18658 pobj assay,by
R13409 T18661 T18657 punct .,detected
R13410 T18662 T18665 det The,number
R13411 T18663 T18665 amod reactive,number
R13412 T18664 T18665 compound cell,number
R13413 T18665 T18667 nsubjpass number,determined
R13414 T18666 T18667 auxpass was,determined
R13415 T18667 T18667 ROOT determined,determined
R13416 T18668 T18667 prep as,determined
R13417 T18669 T18670 det the,number
R13418 T18670 T18668 pobj number,as
R13419 T18671 T18670 prep of,number
R13420 T18672 T18671 pobj DAPI-stained,of
R13421 T18673 T18672 punct ",",DAPI-stained
R13422 T18674 T18675 amod Specific,antibody
R13423 T18675 T18684 nmod antibody,cells
R13424 T18676 T18677 punct (,cleaved
R13425 T18677 T18678 compound cleaved,caspase-3
R13426 T18678 T18675 appos caspase-3,antibody
R13427 T18679 T18678 cc and,caspase-3
R13428 T18680 T18678 conj Bax,caspase-3
R13429 T18681 T18678 punct ),caspase-3
R13430 T18682 T18683 punct -,positive
R13431 T18683 T18684 amod positive,cells
R13432 T18684 T18672 appos cells,DAPI-stained
R13433 T18685 T18687 nsubjpass that,counted
R13434 T18686 T18687 auxpass were,counted
R13435 T18687 T18684 relcl counted,cells
R13436 T18688 T18667 punct .,determined
R13437 T18689 T18690 nsubj Values,are
R13438 T18690 T18690 ROOT are,are
R13439 T18691 T18694 det the,S.D.
R13440 T18692 T18694 amod mean,S.D.
R13441 T18693 T18694 compound ±,S.D.
R13442 T18694 T18690 attr S.D.,are
R13443 T18695 T18694 prep of,S.D.
R13444 T18696 T18698 nummod four,animals
R13445 T18697 T18698 amod experimental,animals
R13446 T18698 T18695 pobj animals,of
R13447 T18699 T18690 punct .,are
R13448 T18700 T18701 nsubj *,indicates
R13449 T18701 T18701 ROOT indicates,indicates
R13450 T18702 T18703 advmod statistically,significant
R13451 T18703 T18704 amod significant,differences
R13452 T18704 T18701 dobj differences,indicates
R13453 T18705 T18704 prep from,differences
R13454 T18706 T18710 nummod CCR5,mice
R13455 T18707 T18710 nummod +,mice
R13456 T18708 T18710 compound /,mice
R13457 T18709 T18710 compound +,mice
R13458 T18710 T18705 pobj mice,from
R13459 T18711 T18701 punct .,indicates
R13460 T18712 T18713 compound Scale,bar
R13461 T18713 T18714 nsubj bar,indicates
R13462 T18714 T18714 ROOT indicates,indicates
R13463 T18715 T18716 nummod 50,µm
R13464 T18716 T18714 dobj µm,indicates
R13465 T18717 T18714 punct .,indicates
R13466 T18718 T18718 ROOT D,D
R13467 T18719 T18718 punct ",",D
R13468 T18720 T18721 det The,expression
R13469 T18721 T18726 nsubjpass expression,detected
R13470 T18722 T18721 prep of,expression
R13471 T18723 T18724 amod apoptotic,proteins
R13472 T18724 T18722 pobj proteins,of
R13473 T18725 T18726 auxpass was,detected
R13474 T18726 T18718 relcl detected,D
R13475 T18727 T18726 agent by,detected
R13476 T18728 T18729 amod Western,blotting
R13477 T18729 T18727 pobj blotting,by
R13478 T18730 T18729 acl using,blotting
R13479 T18731 T18732 amod specific,antibodies
R13480 T18732 T18730 dobj antibodies,using
R13481 T18733 T18718 punct ;,D
R13482 T18734 T18738 nmod cleaved,caspase-9
R13483 T18735 T18738 amod caspase-3,caspase-9
R13484 T18736 T18738 punct ",",caspase-9
R13485 T18737 T18738 amod cleaved,caspase-9
R13486 T18738 T18738 ROOT caspase-9,caspase-9
R13487 T18739 T18741 punct ",",PARP
R13488 T18740 T18741 compound cleaved,PARP
R13489 T18741 T18738 appos PARP,caspase-9
R13490 T18742 T18741 punct ",",PARP
R13491 T18743 T18741 conj Bax,PARP
R13492 T18744 T18743 punct ",",Bax
R13493 T18745 T18743 conj Bcl-2,Bax
R13494 T18746 T18745 cc and,Bcl-2
R13495 T18747 T18745 conj c-IAP1,Bcl-2
R13496 T18748 T18741 prep in,PARP
R13497 T18749 T18751 det the,tissues
R13498 T18750 T18751 compound tumor,tissues
R13499 T18751 T18748 pobj tissues,in
R13500 T18752 T18738 punct .,caspase-9
R13501 T18753 T18755 det The,protein
R13502 T18754 T18755 amod β-actin,protein
R13503 T18755 T18757 nsubjpass protein,used
R13504 T18756 T18757 auxpass was,used
R13505 T18757 T18757 ROOT used,used
R13506 T18758 T18757 prep as,used
R13507 T18759 T18761 det an,control
R13508 T18760 T18761 amod internal,control
R13509 T18761 T18758 pobj control,as
R13510 T18762 T18757 punct .,used
R13511 T18763 T18764 det Each,band
R13512 T18764 T18765 nsubj band,is
R13513 T18765 T18765 ROOT is,is
R13514 T18766 T18765 attr representative,is
R13515 T18767 T18766 prep of,representative
R13516 T18768 T18771 nummod three,results
R13517 T18769 T18771 amod independent,results
R13518 T18770 T18771 amod experimental,results
R13519 T18771 T18767 pobj results,of
R13520 T18772 T18765 punct .,is
R13521 T18773 T18774 nsubj Data,are
R13522 T18774 T18774 ROOT are,are
R13523 T18775 T18774 ccomp means,are
R13524 T18776 T18777 compound ±,S.D.
R13525 T18777 T18775 dobj S.D.,means
R13526 T18778 T18777 prep of,S.D.
R13527 T18779 T18781 nummod three,animals
R13528 T18780 T18781 amod experimental,animals
R13529 T18781 T18778 pobj animals,of
R13530 T18782 T18774 punct .,are
R13531 T18783 T18784 nsubj *,indicates
R13532 T18784 T18784 ROOT indicates,indicates
R13533 T18785 T18786 amod significant,difference
R13534 T18786 T18784 dobj difference,indicates
R13535 T18787 T18786 prep from,difference
R13536 T18788 T18792 nummod CCR5,mice
R13537 T18789 T18792 nummod +,mice
R13538 T18790 T18792 compound /,mice
R13539 T18791 T18792 compound +,mice
R13540 T18792 T18787 pobj mice,from
R13541 T18793 T18792 punct (,mice
R13542 T18794 T18797 dobj p,)
R13543 T18795 T18796 compound <,0.05
R13544 T18796 T18794 nummod 0.05,p
R13545 T18797 T18792 punct ),mice
R13546 T18798 T18784 punct .,indicates
R13803 T19298 T19298 ROOT Upregulation,Upregulation
R13804 T19299 T19298 prep of,Upregulation
R13805 T19300 T19299 pobj IL-1Ra,of
R13806 T19301 T19298 prep in,Upregulation
R13807 T19302 T19303 det the,Tumor
R13808 T19303 T19301 pobj Tumor,in
R13809 T19304 T19303 cc and,Tumor
R13810 T19305 T19298 conj Spleen,Upregulation
R13811 T19306 T19305 prep of,Spleen
R13812 T19307 T19311 nummod CCR5,Mice
R13813 T19308 T19311 nummod −,Mice
R13814 T19309 T19311 nmod /,Mice
R13815 T19310 T19311 compound −,Mice
R13816 T19311 T19306 pobj Mice,of
R13817 T19312 T19298 punct .,Upregulation
R13818 T19313 T19317 quantmod A,indicates
R13819 T19314 T19317 punct ",",indicates
R13820 T19315 T19316 compound Figure,4A
R13821 T19316 T19317 nsubj 4A,indicates
R13822 T19317 T19317 ROOT indicates,indicates
R13823 T19318 T19321 compound mouse,panel
R13824 T19319 T19321 compound cytokine,panel
R13825 T19320 T19321 compound array,panel
R13826 T19321 T19322 nsubj panel,coordinates
R13827 T19322 T19317 ccomp coordinates,indicates
R13828 T19323 T19317 punct .,indicates
R13829 T19324 T19325 amod Nitrocellulose,membranes
R13830 T19325 T19326 nsubj membranes,contain
R13831 T19326 T19326 ROOT contain,contain
R13832 T19327 T19330 nummod 40,antibodies
R13833 T19328 T19330 amod different,antibodies
R13834 T19329 T19330 compound anti-cytokine,antibodies
R13835 T19330 T19326 dobj antibodies,contain
R13836 T19331 T19330 acl printed,antibodies
R13837 T19332 T19331 prep in,printed
R13838 T19333 T19332 pobj duplicate,in
R13839 T19334 T19326 punct .,contain
R13840 T19335 T19341 npadvmod B,indicate
R13841 T19336 T19341 punct ",",indicate
R13842 T19337 T19340 compound Mouse,panel
R13843 T19338 T19340 compound cytokine,panel
R13844 T19339 T19340 compound array,panel
R13845 T19340 T19341 nsubj panel,indicate
R13846 T19341 T19341 ROOT indicate,indicate
R13847 T19342 T19345 det the,difference
R13848 T19343 T19345 compound cytokine,difference
R13849 T19344 T19345 compound expression,difference
R13850 T19345 T19341 dobj difference,indicate
R13851 T19346 T19345 prep in,difference
R13852 T19347 T19348 compound tumor,tissues
R13853 T19348 T19346 pobj tissues,in
R13854 T19349 T19348 prep of,tissues
R13855 T19350 T19354 nummod CCR5,mice
R13856 T19351 T19354 nummod +,mice
R13857 T19352 T19354 compound /,mice
R13858 T19353 T19354 compound +,mice
R13859 T19354 T19349 pobj mice,of
R13860 T19355 T19354 cc and,mice
R13861 T19356 T19354 conj CCR5,mice
R13862 T19357 T19360 nmod −,mice
R13863 T19358 T19360 nummod /,mice
R13864 T19359 T19360 nummod −,mice
R13865 T19360 T19360 ROOT mice,mice
R13866 T19361 T19360 punct ",",mice
R13867 T19362 T19363 advmod especially,IL-1Ra
R13868 T19363 T19360 appos IL-1Ra,mice
R13869 T19364 T19341 punct .,indicate
R13870 T19365 T19366 compound Representative,blot
R13871 T19366 T19372 nsubjpass blot,shown
R13872 T19367 T19366 prep from,blot
R13873 T19368 T19370 nummod three,experiments
R13874 T19369 T19370 amod independent,experiments
R13875 T19370 T19367 pobj experiments,from
R13876 T19371 T19372 auxpass is,shown
R13877 T19372 T19372 ROOT shown,shown
R13878 T19373 T19372 punct .,shown
R13879 T19374 T19375 amod Positive,controls
R13880 T19375 T19376 nsubj controls,show
R13881 T19376 T19376 ROOT show,show
R13882 T19377 T19378 det the,manufacturer
R13883 T19378 T19382 poss manufacturer,samples
R13884 T19379 T19382 amod internal,samples
R13885 T19380 T19381 amod positive,control
R13886 T19381 T19382 compound control,samples
R13887 T19382 T19376 dobj samples,show
R13888 T19383 T19376 prep on,show
R13889 T19384 T19385 det the,membrane
R13890 T19385 T19383 pobj membrane,on
R13891 T19386 T19376 punct .,show
R13892 T19387 T19392 npadvmod C,performed
R13893 T19388 T19392 punct ",",performed
R13894 T19389 T19390 compound Protein,immune-arrays
R13895 T19390 T19392 nsubjpass immune-arrays,performed
R13896 T19391 T19392 auxpass were,performed
R13897 T19392 T19392 ROOT performed,performed
R13898 T19393 T19392 advcl using,performed
R13899 T19394 T19396 compound Mouse,array
R13900 T19395 T19396 compound cytokine,array
R13901 T19396 T19393 dobj array,using
R13902 T19397 T19396 prep in,array
R13903 T19398 T19399 compound spleen,tissues
R13904 T19399 T19397 pobj tissues,in
R13905 T19400 T19392 punct .,performed
R13906 T19401 T19402 expl There,were
R13907 T19402 T19402 ROOT were,were
R13908 T19403 T19402 attr differences,were
R13909 T19404 T19403 prep in,differences
R13910 T19405 T19404 pobj cytokines,in
R13911 T19406 T19403 prep between,differences
R13912 T19407 T19411 nummod CCR5,mice
R13913 T19408 T19411 nummod +,mice
R13914 T19409 T19411 compound /,mice
R13915 T19410 T19411 compound +,mice
R13916 T19411 T19406 pobj mice,between
R13917 T19412 T19411 cc and,mice
R13918 T19413 T19411 conj CCR5,mice
R13919 T19414 T19402 attr −,were
R13920 T19415 T19417 nummod /,mice
R13921 T19416 T19417 nummod −,mice
R13922 T19417 T19414 dobj mice,−
R13923 T19418 T19417 punct ",",mice
R13924 T19419 T19420 advmod especially,IL-1Ra
R13925 T19420 T19417 amod IL-1Ra,mice
R13926 T19421 T19402 punct .,were
R13927 T19422 T19423 compound Representative,blot
R13928 T19423 T19429 nsubjpass blot,shown
R13929 T19424 T19423 prep from,blot
R13930 T19425 T19427 nummod three,experiments
R13931 T19426 T19427 amod independent,experiments
R13932 T19427 T19424 pobj experiments,from
R13933 T19428 T19429 auxpass is,shown
R13934 T19429 T19429 ROOT shown,shown
R13935 T19430 T19429 punct .,shown
R13936 T19431 T19432 amod Positive,controls
R13937 T19432 T19433 nsubj controls,show
R13938 T19433 T19433 ROOT show,show
R13939 T19434 T19435 det the,manufacturer
R13940 T19435 T19439 poss manufacturer,samples
R13941 T19436 T19438 amod internal,control
R13942 T19437 T19438 amod positive,control
R13943 T19438 T19439 compound control,samples
R13944 T19439 T19433 dobj samples,show
R13945 T19440 T19439 prep on,samples
R13946 T19441 T19442 det the,membrane
R13947 T19442 T19440 pobj membrane,on
R13948 T19443 T19433 punct .,show
R13949 T19444 T19451 nsubjpass D,used
R13950 T19445 T19444 cc and,D
R13951 T19446 T19444 conj E,D
R13952 T19447 T19444 punct ",",D
R13953 T19448 T19449 compound Immunolfluorescence,analysis
R13954 T19449 T19444 appos analysis,D
R13955 T19450 T19451 auxpass was,used
R13956 T19451 T19451 ROOT used,used
R13957 T19452 T19453 aux to,determine
R13958 T19453 T19451 xcomp determine,used
R13959 T19454 T19456 det the,levels
R13960 T19455 T19456 compound expression,levels
R13961 T19456 T19453 dobj levels,determine
R13962 T19457 T19456 prep of,levels
R13963 T19458 T19457 pobj IL-1Ra,of
R13964 T19459 T19453 prep in,determine
R13965 T19460 T19463 nmod tumor,tissues
R13966 T19461 T19460 cc and,tumor
R13967 T19462 T19460 conj spleen,tumor
R13968 T19463 T19459 pobj tissues,in
R13969 T19464 T19451 punct .,used
R13970 T19465 T19468 det The,number
R13971 T19466 T19468 amod reactive,number
R13972 T19467 T19468 compound cell,number
R13973 T19468 T19470 nsubjpass number,determined
R13974 T19469 T19470 auxpass was,determined
R13975 T19470 T19470 ROOT determined,determined
R13976 T19471 T19470 prep as,determined
R13977 T19472 T19473 det the,number
R13978 T19473 T19471 pobj number,as
R13979 T19474 T19473 prep of,number
R13980 T19475 T19479 amod DAPI-stained,cells
R13981 T19476 T19479 punct ",",cells
R13982 T19477 T19479 amod IL-1Ra,cells
R13983 T19478 T19479 amod antibody-positive,cells
R13984 T19479 T19474 pobj cells,of
R13985 T19480 T19482 nsubjpass that,counted
R13986 T19481 T19482 auxpass were,counted
R13987 T19482 T19479 relcl counted,cells
R13988 T19483 T19470 punct .,determined
R13989 T19484 T19485 nsubj Values,are
R13990 T19485 T19485 ROOT are,are
R13991 T19486 T19489 det the,S.D.
R13992 T19487 T19489 amod mean,S.D.
R13993 T19488 T19489 compound ±,S.D.
R13994 T19489 T19485 attr S.D.,are
R13995 T19490 T19489 prep of,S.D.
R13996 T19491 T19493 nummod four,animals
R13997 T19492 T19493 amod experimental,animals
R13998 T19493 T19490 pobj animals,of
R13999 T19494 T19485 punct .,are
R14000 T19495 T19496 nsubj *,indicates
R14001 T19496 T19496 ROOT indicates,indicates
R14002 T19497 T19498 advmod statistically,significant
R14003 T19498 T19499 amod significant,differences
R14004 T19499 T19496 dobj differences,indicates
R14005 T19500 T19499 prep from,differences
R14006 T19501 T19505 nummod CCR5,mice
R14007 T19502 T19505 nummod +,mice
R14008 T19503 T19505 compound /,mice
R14009 T19504 T19505 compound +,mice
R14010 T19505 T19500 pobj mice,from
R14011 T19506 T19496 punct .,indicates
R14012 T19507 T19508 compound Scale,bar
R14013 T19508 T19509 nsubj bar,indicates
R14014 T19509 T19509 ROOT indicates,indicates
R14015 T19510 T19511 nummod 50,µm
R14016 T19511 T19509 dobj µm,indicates
R14017 T19512 T19509 punct .,indicates
R14018 T19513 T19521 nsubjpass F,analyzed
R14019 T19514 T19513 cc and,F
R14020 T19515 T19513 conj G,F
R14021 T19516 T19515 punct ",",G
R14022 T19517 T19515 conj Expression,G
R14023 T19518 T19517 prep of,Expression
R14024 T19519 T19518 pobj IL-1Ra,of
R14025 T19520 T19521 auxpass was,analyzed
R14026 T19521 T19521 ROOT analyzed,analyzed
R14027 T19522 T19521 agent by,analyzed
R14028 T19523 T19524 amod western,blotting
R14029 T19524 T19522 pobj blotting,by
R14030 T19525 T19524 prep in,blotting
R14031 T19526 T19529 nmod tumor,tissues
R14032 T19527 T19526 cc and,tumor
R14033 T19528 T19529 compound spleen,tissues
R14034 T19529 T19525 pobj tissues,in
R14035 T19530 T19521 punct .,analyzed
R14036 T19531 T19532 det Each,band
R14037 T19532 T19533 nsubj band,is
R14038 T19533 T19533 ROOT is,is
R14039 T19534 T19533 attr representative,is
R14040 T19535 T19534 prep of,representative
R14041 T19536 T19539 nummod three,results
R14042 T19537 T19539 amod independent,results
R14043 T19538 T19539 amod experimental,results
R14044 T19539 T19535 pobj results,of
R14045 T19540 T19533 punct .,is
R14046 T19541 T19542 nsubj Data,are
R14047 T19542 T19542 ROOT are,are
R14048 T19543 T19542 ccomp means,are
R14049 T19544 T19543 dobj ±,means
R14050 T19545 T19544 appos S.D.,±
R14051 T19546 T19545 prep of,S.D.
R14052 T19547 T19549 nummod three,animals
R14053 T19548 T19549 amod experimental,animals
R14054 T19549 T19546 pobj animals,of
R14055 T19550 T19542 punct .,are
R14056 T19551 T19552 nsubj *,indicates
R14057 T19552 T19552 ROOT indicates,indicates
R14058 T19553 T19554 amod significant,difference
R14059 T19554 T19552 dobj difference,indicates
R14060 T19555 T19552 prep from,indicates
R14061 T19556 T19560 nummod CCR5,mice
R14062 T19557 T19560 nummod +,mice
R14063 T19558 T19560 compound /,mice
R14064 T19559 T19560 compound +,mice
R14065 T19560 T19555 pobj mice,from
R14066 T19561 T19560 punct (,mice
R14067 T19562 T19565 dobj p,)
R14068 T19563 T19564 compound <,0.05
R14069 T19564 T19562 nummod 0.05,p
R14070 T19565 T19560 punct ),mice
R14071 T19566 T19552 punct .,indicates
R14203 T19754 T19754 ROOT Induction,Induction
R14204 T19755 T19754 prep of,Induction
R14205 T19756 T19757 det the,infiltration
R14206 T19757 T19755 pobj infiltration,of
R14207 T19758 T19757 prep of,infiltration
R14208 T19759 T19762 nummod CD8,cells
R14209 T19760 T19762 nummod +,cells
R14210 T19761 T19762 compound T,cells
R14211 T19762 T19758 pobj cells,of
R14212 T19763 T19762 cc and,cells
R14213 T19764 T19765 compound NK,cells
R14214 T19765 T19762 conj cells,cells
R14215 T19766 T19757 prep into,infiltration
R14216 T19767 T19766 pobj tumor,into
R14217 T19768 T19754 punct ",",Induction
R14218 T19769 T19754 cc and,Induction
R14219 T19770 T19754 conj increase,Induction
R14220 T19771 T19770 prep in,increase
R14221 T19772 T19771 pobj spleen,in
R14222 T19773 T19772 prep of,spleen
R14223 T19774 T19778 nummod CCR5,mice
R14224 T19775 T19778 nummod −,mice
R14225 T19776 T19778 nmod /,mice
R14226 T19777 T19778 compound −,mice
R14227 T19778 T19773 pobj mice,of
R14228 T19779 T19754 punct .,Induction
R14229 T19780 T19785 det A,analysis
R14230 T19781 T19780 cc and,A
R14231 T19782 T19785 nmod B,analysis
R14232 T19783 T19785 punct ",",analysis
R14233 T19784 T19785 compound Immunolfluorescence,analysis
R14234 T19785 T19787 nsubjpass analysis,used
R14235 T19786 T19787 auxpass was,used
R14236 T19787 T19787 ROOT used,used
R14237 T19788 T19789 aux to,determine
R14238 T19789 T19787 xcomp determine,used
R14239 T19790 T19792 det the,levels
R14240 T19791 T19792 compound expression,levels
R14241 T19792 T19789 dobj levels,determine
R14242 T19793 T19792 prep of,levels
R14243 T19794 T19793 pobj CD8,of
R14244 T19795 T19794 punct (,CD8
R14245 T19796 T19801 nmod CD8,marker
R14246 T19797 T19801 nmod +,marker
R14247 T19798 T19801 amod cytotoxic,marker
R14248 T19799 T19801 compound T-cell,marker
R14249 T19800 T19801 compound surface,marker
R14250 T19801 T19794 appos marker,CD8
R14251 T19802 T19794 punct ),CD8
R14252 T19803 T19794 cc and,CD8
R14253 T19804 T19794 conj CD57,CD8
R14254 T19805 T19808 punct (,marker
R14255 T19806 T19808 compound NK,marker
R14256 T19807 T19808 compound cell,marker
R14257 T19808 T19804 appos marker,CD57
R14258 T19809 T19808 punct ),marker
R14259 T19810 T19789 prep in,determine
R14260 T19811 T19814 nmod tumor,sections
R14261 T19812 T19811 cc and,tumor
R14262 T19813 T19811 conj spleen,tumor
R14263 T19814 T19810 pobj sections,in
R14264 T19815 T19787 punct .,used
R14265 T19816 T19817 det The,images
R14266 T19817 T19819 nsubj images,are
R14267 T19818 T19817 acl shown,images
R14268 T19819 T19819 ROOT are,are
R14269 T19820 T19819 attr representative,are
R14270 T19821 T19820 prep of,representative
R14271 T19822 T19824 nummod three,experiments
R14272 T19823 T19824 amod separate,experiments
R14273 T19824 T19821 pobj experiments,of
R14274 T19825 T19824 acl performed,experiments
R14275 T19826 T19825 prep in,performed
R14276 T19827 T19826 pobj triplicate,in
R14277 T19828 T19819 punct .,are
R14278 T19829 T19830 compound Scale,bars
R14279 T19830 T19831 nsubj bars,indicate
R14280 T19831 T19831 ROOT indicate,indicate
R14281 T19832 T19833 nummod 50,µm
R14282 T19833 T19831 dobj µm,indicate
R14283 T19834 T19835 punct (,A
R14284 T19835 T19833 parataxis A,µm
R14285 T19836 T19835 punct ),A
R14286 T19837 T19833 cc and,µm
R14287 T19838 T19839 nummod 100,µm
R14288 T19839 T19833 conj µm,µm
R14289 T19840 T19841 punct (,B
R14290 T19841 T19839 appos B,µm
R14291 T19842 T19839 punct ),µm
R14292 T19843 T19831 punct .,indicate
R14293 T19844 T19844 ROOT C,C
R14294 T19845 T19844 cc and,C
R14295 T19846 T19844 conj D,C
R14296 T19847 T19846 punct ",",D
R14297 T19848 T19846 conj Analysis,D
R14298 T19849 T19848 prep of,Analysis
R14299 T19850 T19851 compound lymphocyte,phenotypes
R14300 T19851 T19849 pobj phenotypes,of
R14301 T19852 T19844 punct .,C
R14302 T19853 T19854 det The,tumor
R14303 T19854 T19859 nsubjpass tumor,separated
R14304 T19855 T19854 cc and,tumor
R14305 T19856 T19857 compound spleen,tissues
R14306 T19857 T19854 conj tissues,tumor
R14307 T19858 T19859 auxpass were,separated
R14308 T19859 T19859 ROOT separated,separated
R14309 T19860 T19859 prep at,separated
R14310 T19861 T19862 compound study,termination
R14311 T19862 T19860 pobj termination,at
R14312 T19863 T19864 punct (,Day
R14313 T19864 T19862 appos Day,termination
R14314 T19865 T19864 nummod 31,Day
R14315 T19866 T19864 punct ),Day
R14316 T19867 T19859 punct .,separated
R14317 T19868 T19870 compound Flow,analysis
R14318 T19869 T19870 compound cytometry,analysis
R14319 T19870 T19872 nsubjpass analysis,performed
R14320 T19871 T19872 auxpass was,performed
R14321 T19872 T19872 ROOT performed,performed
R14322 T19873 T19872 advcl using,performed
R14323 T19874 T19876 compound FACSAria,cytometry
R14324 T19875 T19876 compound flow,cytometry
R14325 T19876 T19873 dobj cytometry,using
R14326 T19877 T19872 punct ",",performed
R14327 T19878 T19872 cc and,performed
R14328 T19879 T19872 conj represent,performed
R14329 T19880 T19882 nsubjpass data,shown
R14330 T19881 T19882 auxpass were,shown
R14331 T19882 T19879 ccomp shown,represent
R14332 T19883 T19872 punct .,performed
R14333 T19884 T19885 nsubj Data,are
R14334 T19885 T19885 ROOT are,are
R14335 T19886 T19885 ccomp means,are
R14336 T19887 T19888 compound ±,S.D.
R14337 T19888 T19886 dobj S.D.,means
R14338 T19889 T19888 prep of,S.D.
R14339 T19890 T19892 nummod four,animals
R14340 T19891 T19892 amod experimental,animals
R14341 T19892 T19889 pobj animals,of
R14342 T19893 T19885 punct .,are
R2007 T3164 T3165 nsubj Chemokines,are
R2010 T3165 T3165 ROOT are,are
R2012 T3166 T3168 amod small,molecules
R2014 T3167 T3168 amod soluble,molecules
R2017 T3168 T3165 attr molecules,are
R2019 T3169 T3172 nsubjpass that,known
R2020 T3170 T3172 auxpass are,known
R2022 T3171 T3172 advmod best,known
R2023 T3172 T3168 relcl known,molecules
R2024 T3173 T3172 prep for,known
R2025 T3174 T3176 poss their,ability
R2026 T3175 T3176 amod potent,ability
R2027 T3214 T3213 punct ),CCL5
R2028 T3176 T3173 pobj ability,for
R2029 T3177 T3178 aux to,induce
R2030 T3178 T3176 acl induce,ability
R2031 T3179 T3180 compound cancer,cell
R2032 T3180 T3181 compound cell,growth
R2033 T3181 T3178 dobj growth,induce
R2034 T3182 T3178 prep by,induce
R2035 T3183 T3182 pobj inflammation,by
R2036 T3184 T3165 punct .,are
R2037 T3185 T3186 amod Many,types
R2038 T3215 T3213 cc and,CCL5
R2039 T3186 T3190 nsubj types,express
R2040 T3187 T3186 prep of,types
R2041 T3188 T3189 compound cancer,cells
R2042 T3216 T3218 compound C-C,receptor
R2043 T3189 T3187 pobj cells,of
R2044 T3190 T3190 ROOT express,express
R2045 T3191 T3190 dobj chemokines,express
R2046 T3192 T3191 cc and,chemokines
R2047 T3217 T3218 compound chemokine,receptor
R2048 T3193 T3194 compound chemokine,receptors
R2049 T3194 T3191 conj receptors,chemokines
R2050 T3195 T3190 conj [,express
R2051 T3196 T3197 nummod 1,]
R2052 T3197 T3195 dobj ],[
R2053 T3198 T3190 punct .,express
R2054 T3199 T3201 det The,evidence
R2055 T3218 T3213 conj receptor,CCL5
R2056 T3200 T3201 amod accumulated,evidence
R2057 T3201 T3202 nsubj evidence,indicates
R2058 T3202 T3202 ROOT indicates,indicates
R2059 T3203 T3235 mark that,involved
R2060 T3219 T3220 punct (,CCR5
R2061 T3204 T3205 det the,chemokine
R2062 T3205 T3235 nsubjpass chemokine,involved
R2063 T3206 T3208 punct (,motif
R2064 T3220 T3218 appos CCR5,receptor
R2065 T3207 T3208 amod C-C,motif
R2066 T3208 T3205 appos motif,chemokine
R2067 T3209 T3205 punct ),chemokine
R2068 T3221 T3220 punct ),CCR5
R2069 T3210 T3213 nmod ligand,CCL5
R2070 T3211 T3210 nummod 5,ligand
R2071 T3212 T3213 punct (,CCL5
R2072 T3213 T3235 nsubjpass CCL5,involved
R2073 T3222 T3218 punct ",",receptor
R2074 T3223 T3224 nsubj which,are
R2075 T3224 T3218 relcl are,receptor
R2076 T3225 T3227 amod potent,factors
R2077 T3226 T3227 compound chemotactic,factors
R2078 T3311 T3309 cc and,]
R2079 T3227 T3224 attr factors,are
R2080 T3312 T3313 advmod also,correlates
R2081 T3313 T3298 conj correlates,is
R2082 T3228 T3227 prep for,factors
R2083 T3314 T3313 prep with,correlates
R2084 T3315 T3316 amod poor,prognosis
R2085 T3316 T3317 compound prognosis,[
R2086 T3317 T3319 nmod [,]
R2087 T3229 T3230 amod inflammatory,cells
R2088 T3318 T3319 nummod 8,]
R2089 T3319 T3314 pobj ],with
R2090 T3230 T3228 pobj cells,for
R2091 T3320 T3313 punct .,correlates
R2092 T3321 T3327 advmod Meanwhile,demonstrated
R2093 T3322 T3327 punct ",",demonstrated
R2094 T3231 T3218 punct ",",receptor
R2095 T3323 T3324 compound CCR5,disruption
R2096 T3324 T3327 nsubjpass disruption,demonstrated
R2097 T3325 T3327 aux has,demonstrated
R2098 T3232 T3235 aux may,involved
R2099 T3233 T3235 auxpass be,involved
R2100 T3326 T3327 auxpass been,demonstrated
R2101 T3234 T3235 advmod significantly,involved
R2102 T3327 T3327 ROOT demonstrated,demonstrated
R2103 T3328 T3329 aux to,inhibit
R2104 T3329 T3327 xcomp inhibit,demonstrated
R2105 T3330 T3332 amod experimental,growth
R2106 T3331 T3332 compound tumor,growth
R2107 T3235 T3202 ccomp involved,indicates
R2108 T3332 T3329 dobj growth,inhibit
R2109 T3333 T3332 cc and,growth
R2110 T3334 T3332 conj metastasis,growth
R2111 T3236 T3235 prep in,involved
R2112 T3335 T3334 prep of,metastasis
R2113 T3336 T3337 compound pancreatic,cancer
R2114 T3337 T3338 compound cancer,[
R2115 T3237 T3238 det the,proliferation
R2116 T3338 T3340 nmod [,]
R2117 T3339 T3338 nummod 9,[
R2118 T3340 T3335 pobj ],of
R2119 T3238 T3236 pobj proliferation,in
R2120 T3341 T3327 punct .,demonstrated
R2121 T3342 T3362 prep In,prevented
R2122 T3343 T3342 pobj addition,In
R2123 T3344 T3362 punct ",",prevented
R2124 T3239 T3238 cc and,proliferation
R2125 T3345 T3346 compound host,absence
R2126 T3346 T3362 nsubj absence,prevented
R2127 T3347 T3346 prep of,absence
R2128 T3348 T3349 nummod CCR5,potentiates
R2129 T3240 T3238 conj metastasis,proliferation
R2130 T3349 T3347 pobj potentiates,of
R2131 T3350 T3351 det the,delay
R2132 T3351 T3346 conj delay,absence
R2133 T3241 T3238 prep of,proliferation
R2134 T3352 T3351 prep of,delay
R2135 T3353 T3354 compound tumor,growth
R2136 T3354 T3352 pobj growth,of
R2137 T3355 T3357 nmod [,]
R2138 T3242 T3243 amod several,cancers
R2139 T3356 T3357 nummod 10,]
R2140 T3357 T3361 nmod ],inhibitors
R2141 T3358 T3357 punct ",",]
R2142 T3243 T3241 pobj cancers,of
R2143 T3359 T3357 cc and,]
R2144 T3360 T3357 conj CCR5,]
R2145 T3361 T3362 nsubj inhibitors,prevented
R2146 T3362 T3362 ROOT prevented,prevented
R2147 T3244 T3202 punct .,indicates
R2148 T3363 T3364 compound cancer,cell
R2149 T3364 T3365 compound cell,growth
R2150 T3365 T3362 dobj growth,prevented
R2151 T3245 T3252 nsubjpass Intermediate,associated
R2152 T3366 T3362 punct ",",prevented
R2153 T3367 T3368 amod such,as
R2154 T3368 T3362 prep as,prevented
R2155 T3369 T3370 compound prostate,cancer
R2156 T3370 T3371 compound cancer,[
R2157 T3371 T3368 pobj [,as
R2158 T3246 T3245 cc and,Intermediate
R2159 T3372 T3373 nummod 11,]
R2160 T3247 T3249 amod strong,expression
R2161 T3248 T3249 compound CCR5,expression
R2162 T3373 T3371 conj ],[
R2163 T3374 T3373 punct ",",]
R2164 T3249 T3245 conj expression,Intermediate
R2165 T3375 T3376 compound breast,cancer
R2166 T3376 T3371 conj cancer,[
R2167 T3250 T3252 auxpass is,associated
R2168 T3377 T3376 punct ",",cancer
R2169 T3378 T3379 compound hepatoma,cells
R2170 T3251 T3252 advmod significantly,associated
R2171 T3379 T3376 conj cells,cancer
R2172 T3380 T3382 nmod [,]
R2173 T3381 T3382 nummod 4,]
R2174 T3252 T3252 ROOT associated,associated
R2175 T3382 T3362 dobj ],prevented
R2176 T3383 T3382 punct ",",]
R2177 T3384 T3382 cc and,]
R2178 T3385 T3386 compound lung,cancer
R2179 T3253 T3252 prep with,associated
R2180 T3386 T3387 compound cancer,[
R2181 T3387 T3382 conj [,]
R2182 T3388 T3389 nummod 12,]
R2183 T3254 T3255 amod nonmetastatic,development
R2184 T3389 T3387 appos ],[
R2185 T3390 T3362 punct .,prevented
R2186 T3391 T3392 det These,data
R2187 T3255 T3253 pobj development,with
R2188 T3392 T3393 nsubj data,suggest
R2189 T3393 T3393 ROOT suggest,suggest
R2190 T3394 T3403 mark that,function
R2191 T3395 T3396 det the,deficiency
R2192 T3256 T3255 prep of,development
R2193 T3396 T3403 nsubj deficiency,function
R2194 T3397 T3396 prep of,deficiency
R2195 T3398 T3401 amod inflammatory,CCR5
R2196 T3257 T3258 compound colorectal,cancer
R2197 T3399 T3400 compound chemokine,receptor
R2198 T3400 T3401 compound receptor,CCR5
R2199 T3258 T3259 compound cancer,[
R2200 T3401 T3397 pobj CCR5,of
R2201 T3402 T3403 aux may,function
R2202 T3403 T3393 ccomp function,suggest
R2203 T3404 T3403 prep as,function
R2204 T3259 T3256 pobj [,of
R2205 T3260 T3261 nummod 2,]
R2206 T3405 T3407 det a,receptor
R2207 T3261 T3269 nmod ],[
R2208 T3262 T3261 punct ",",]
R2209 T3406 T3407 compound suppressive,receptor
R2210 T3407 T3404 pobj receptor,as
R2211 T3408 T3407 prep in,receptor
R2212 T3263 T3264 compound melanoma,[
R2213 T3264 T3261 appos [,]
R2214 T3265 T3264 nummod 3,[
R2215 T3409 T3410 compound cancer,progression
R2216 T3266 T3261 conj ],]
R2217 T3410 T3408 pobj progression,in
R2218 T3411 T3393 punct .,suggest
R2219 T3412 T3417 advmod However,required
R2220 T3267 T3266 punct ",",]
R2221 T3413 T3417 punct ",",required
R2222 T3414 T3415 amod more,studies
R2223 T3268 T3269 compound hepatoma,[
R2224 T3415 T3417 nsubjpass studies,required
R2225 T3416 T3417 auxpass are,required
R2226 T3417 T3417 ROOT required,required
R2227 T3269 T3271 nmod [,]
R2228 T3418 T3419 aux to,describe
R2229 T3419 T3417 xcomp describe,required
R2230 T3420 T3423 advmod how,acts
R2231 T3270 T3271 nummod 4,]
R2232 T3421 T3423 amod CCR5,acts
R2233 T3422 T3423 compound deficiency,acts
R2234 T3423 T3419 dobj acts,describe
R2235 T3271 T3289 nsubj ],[
R2236 T3424 T3423 prep in,acts
R2237 T3425 T3426 det the,inhibition
R2238 T3426 T3424 pobj inhibition,in
R2239 T3427 T3426 prep of,inhibition
R2240 T3272 T3271 punct ",",]
R2241 T3428 T3429 compound tumor,development
R2242 T3429 T3427 pobj development,of
R2243 T3430 T3417 punct .,required
R2244 T3431 T3433 compound Interleukin-1,antagonist
R2245 T3273 T3271 conj glioblastoma,]
R2246 T3432 T3433 compound receptor,antagonist
R2247 T3433 T3445 nsubj antagonist,is
R2248 T3434 T3433 punct (,antagonist
R2249 T3435 T3433 appos IL-1Ra,antagonist
R2250 T3274 T3273 punct ",",glioblastoma
R2251 T3436 T3433 punct ),antagonist
R2252 T3437 T3433 punct ",",antagonist
R2253 T3438 T3439 det a,member
R2254 T3439 T3433 appos member,antagonist
R2255 T3440 T3439 prep of,member
R2256 T3441 T3443 det the,family
R2257 T3442 T3443 amod IL-1,family
R2258 T3275 T3276 compound Hodgkin,lymphoma
R2259 T3443 T3440 pobj family,of
R2260 T3444 T3445 punct ",",is
R2261 T3445 T3445 ROOT is,is
R2262 T3446 T3449 det a,cytokine
R2263 T3276 T3277 compound lymphoma,[
R2264 T3447 T3448 advmod naturally,occurring
R2265 T3448 T3449 amod occurring,cytokine
R2266 T3449 T3445 attr cytokine,is
R2267 T3277 T3273 appos [,glioblastoma
R2268 T3450 T3452 nsubj that,blocks
R2269 T3451 T3452 advmod competitively,blocks
R2270 T3452 T3449 relcl blocks,cytokine
R2271 T3278 T3277 nummod 5,[
R2272 T3453 T3455 det the,receptor
R2273 T3454 T3455 amod IL-1,receptor
R2274 T3455 T3452 dobj receptor,blocks
R2275 T3279 T3277 appos ],[
R2276 T3456 T3458 nmod [,]
R2277 T3457 T3458 nummod 13,]
R2278 T3458 T3449 appos ],cytokine
R2279 T3280 T3277 punct ",",[
R2280 T3459 T3445 punct .,is
R2281 T3460 T3464 mark Because,shown
R2282 T3461 T3464 nsubjpass IL-1Ra,shown
R2283 T3281 T3283 advmod as,as
R2284 T3462 T3464 aux has,shown
R2285 T3463 T3464 auxpass been,shown
R2286 T3464 T3464 ROOT shown,shown
R2287 T3465 T3466 aux to,inhibit
R2288 T3282 T3283 advmod well,as
R2289 T3466 T3464 xcomp inhibit,shown
R2290 T3467 T3468 compound tumor,progression
R2291 T3468 T3466 dobj progression,inhibit
R2292 T3283 T3277 cc as,[
R2293 T3469 T3466 prep by,inhibit
R2294 T3470 T3469 pcomp promoting,by
R2295 T3471 T3473 amod antitumor,responses
R2296 T3284 T3288 amod oral,cells
R2297 T3472 T3473 amod immune,responses
R2298 T3473 T3470 dobj responses,promoting
R2299 T3474 T3469 cc and,by
R2300 T3285 T3284 cc and,oral
R2301 T3475 T3469 conj by,by
R2302 T3476 T3475 pcomp enhancing,by
R2303 T3477 T3478 det the,activity
R2304 T3478 T3476 dobj activity,enhancing
R2305 T3479 T3478 prep of,activity
R2306 T3480 T3483 amod chemotherapy,studies
R2307 T3286 T3284 conj prostate,oral
R2308 T3481 T3483 punct ",",studies
R2309 T3482 T3483 amod numerous,studies
R2310 T3483 T3479 pobj studies,of
R2311 T3287 T3288 compound cancer,cells
R2312 T3288 T3277 conj cells,[
R2313 T3484 T3485 aux have,examined
R2314 T3289 T3252 conj [,associated
R2315 T3290 T3291 nummod 6,]
R2316 T3485 T3464 conj examined,shown
R2317 T3291 T3289 dobj ],[
R2318 T3486 T3487 det the,ability
R2319 T3292 T3289 punct .,[
R2320 T3293 T3294 amod Local,production
R2321 T3294 T3298 nsubj production,is
R2322 T3487 T3485 dobj ability,examined
R2323 T3295 T3294 prep of,production
R2324 T3296 T3297 det the,CCL5
R2325 T3488 T3487 prep of,ability
R2326 T3297 T3295 pobj CCL5,of
R2327 T3298 T3298 ROOT is,is
R2328 T3489 T3488 pobj IL-1Ra,of
R2329 T3299 T3298 advmod also,is
R2330 T3300 T3298 acomp important,is
R2331 T3490 T3491 aux to,block
R2332 T3301 T3298 prep in,is
R2333 T3491 T3487 acl block,ability
R2334 T3302 T3303 det the,progression
R2335 T3303 T3301 pobj progression,in
R2336 T3492 T3493 compound tumor,progression
R2337 T3493 T3491 dobj progression,block
R2338 T3304 T3303 prep of,progression
R2339 T3494 T3464 punct .,shown
R2340 T3495 T3496 compound IL-1Ra,expression
R2341 T3496 T3498 nsubjpass expression,reduced
R2342 T3305 T3306 compound breast,cancer
R2343 T3497 T3498 auxpass was,reduced
R2344 T3498 T3498 ROOT reduced,reduced
R2345 T3499 T3498 prep in,reduced
R2346 T3306 T3304 pobj cancer,of
R2347 T3500 T3499 pobj prostate,in
R2348 T3501 T3503 nmod [,]
R2349 T3307 T3309 nmod [,]
R2350 T3502 T3503 nummod 14,]
R2351 T3503 T3498 npadvmod ],reduced
R2352 T3504 T3503 punct ",",]
R2353 T3505 T3506 compound breast,[
R2354 T3308 T3309 nummod 7,]
R2355 T3309 T3313 nsubj ],correlates
R2356 T3506 T3503 conj [,]
R2357 T3310 T3309 punct ",",]
R2358 T3507 T3508 nummod 15,]
R2359 T3508 T3506 conj ],[
R2360 T3509 T3508 punct ",",]
R2361 T3603 T3601 cc and,]
R2362 T3510 T3508 cc and,]
R2363 T3511 T3512 compound skin,cancer
R2364 T3512 T3513 compound cancer,[
R2365 T3604 T3605 compound skin,cancer
R2366 T3513 T3508 conj [,]
R2367 T3514 T3515 nummod 16,]
R2368 T3515 T3513 appos ],[
R2369 T3516 T3498 punct .,reduced
R2370 T3605 T3606 compound cancer,development
R2371 T3517 T3520 nsubjpass It,reported
R2372 T3518 T3520 auxpass was,reported
R2373 T3519 T3520 advmod also,reported
R2374 T3606 T3580 dobj development,reduces
R2375 T3520 T3520 ROOT reported,reported
R2376 T3521 T3526 mark that,developed
R2377 T3522 T3525 amod endogenous,mice
R2378 T3607 T3609 nmod [,]
R2379 T3523 T3525 compound IL-1Ra,mice
R2380 T3524 T3525 compound deficient,mice
R2381 T3525 T3526 nsubj mice,developed
R2382 T3608 T3609 nummod 23,]
R2383 T3526 T3520 ccomp developed,reported
R2384 T3527 T3528 amod aggressive,tumors
R2385 T3528 T3526 dobj tumors,developed
R2386 T3609 T3580 npadvmod ],reduces
R2387 T3529 T3526 prep following,developed
R2388 T3530 T3529 pobj exposure,following
R2389 T3531 T3530 prep to,exposure
R2390 T3610 T3577 punct .,reported
R2391 T3532 T3531 pobj carcinogens,to
R2392 T3533 T3535 nmod [,]
R2393 T3534 T3533 nummod 17,[
R2394 T3611 T3613 nummod IL-1,mice
R2395 T3535 T3532 appos ],carcinogens
R2396 T3536 T3520 punct .,reported
R2397 T3612 T3613 compound knockout,mice
R2398 T3537 T3551 advmod Meanwhile,reduced
R2399 T3538 T3551 punct ",",reduced
R2400 T3539 T3551 nsubjpass proliferation,reduced
R2401 T3613 T3617 nsubj mice,failed
R2402 T3540 T3539 prep of,proliferation
R2403 T3541 T3543 det the,cells
R2404 T3542 T3543 compound melanoma,cells
R2405 T3543 T3540 pobj cells,of
R2406 T3544 T3546 nsubjpass that,transduced
R2407 T3545 T3546 auxpass were,transduced
R2408 T3614 T3613 acl injected,mice
R2409 T3546 T3543 relcl transduced,cells
R2410 T3547 T3546 prep with,transduced
R2411 T3548 T3549 amod IL-1Ra,gene
R2412 T3615 T3614 prep with,injected
R2413 T3549 T3547 pobj gene,with
R2414 T3550 T3551 auxpass was,reduced
R2415 T3551 T3551 ROOT reduced,reduced
R2416 T3616 T3615 pobj melanoma,with
R2417 T3552 T3551 cc and,reduced
R2418 T3553 T3551 conj inhibited,reduced
R2419 T3554 T3555 compound melanoma,development
R2420 T3555 T3553 dobj development,inhibited
R2421 T3617 T3617 ROOT failed,failed
R2422 T3556 T3558 nmod [,]
R2423 T3557 T3558 nummod 18,]
R2424 T3558 T3555 appos ],development
R2425 T3618 T3619 aux to,develop
R2426 T3559 T3551 punct .,reduced
R2427 T3560 T3561 compound IL-1R,blockade
R2428 T3561 T3563 nsubj blockade,reduced
R2429 T3619 T3617 xcomp develop,failed
R2430 T3620 T3621 amod solid,tumors
R2431 T3562 T3563 advmod also,reduced
R2432 T3621 T3619 dobj tumors,develop
R2433 T3563 T3563 ROOT reduced,reduced
R2434 T3564 T3566 amod hepatic,growth
R2435 T3622 T3624 nsubj [,]
R2436 T3565 T3566 compound tumor,growth
R2437 T3566 T3563 dobj growth,reduced
R2438 T3567 T3569 nmod [,]
R2439 T3623 T3624 nummod 24,]
R2440 T3568 T3569 nummod 19,]
R2441 T3569 T3566 appos ],growth
R2442 T3624 T3617 dep ],failed
R2443 T3570 T3563 punct .,reduced
R2444 T3625 T3617 punct .,failed
R2445 T3571 T3577 advmod Moreover,reported
R2446 T3572 T3577 punct ",",reported
R2447 T3573 T3577 nsubj it,reported
R2448 T3626 T3629 nsubjpass It,found
R2449 T3574 T3577 aux has,reported
R2450 T3575 T3577 advmod also,reported
R2451 T3576 T3577 auxpass been,reported
R2452 T3627 T3629 auxpass was,found
R2453 T3577 T3577 ROOT reported,reported
R2454 T3578 T3580 mark that,reduces
R2455 T3579 T3580 nsubj IL-1Ra,reduces
R2456 T3580 T3577 ccomp reduces,reported
R2457 T3581 T3582 compound fibrosarcoma,development
R2458 T3582 T3580 dobj development,reduces
R2459 T3628 T3629 advmod also,found
R2460 T3583 T3585 nmod [,]
R2461 T3584 T3585 nummod 20,]
R2462 T3585 T3606 nmod ],development
R2463 T3629 T3629 ROOT found,found
R2464 T3586 T3585 punct ",",]
R2465 T3587 T3589 compound B16,growth
R2466 T3588 T3589 compound melanoma,growth
R2467 T3630 T3640 mark that,demonstrated
R2468 T3589 T3585 appos growth,]
R2469 T3590 T3589 cc and,growth
R2470 T3591 T3592 compound metastasis,[
R2471 T3631 T3640 nsubj IL-1Ra,demonstrated
R2472 T3592 T3585 conj [,]
R2473 T3593 T3594 nummod 21,]
R2474 T3594 T3594 ROOT ],]
R2475 T3632 T3631 punct ",",IL-1Ra
R2476 T3595 T3594 punct ",",]
R2477 T3596 T3597 compound colon,adenocarcinoma
R2478 T3597 T3598 compound adenocarcinoma,growth
R2479 T3633 T3631 acl combined,IL-1Ra
R2480 T3598 T3599 compound growth,[
R2481 T3599 T3592 conj [,[
R2482 T3600 T3601 nummod 22,]
R2483 T3634 T3633 prep with,combined
R2484 T3601 T3599 conj ],[
R2485 T3602 T3601 punct ",",]
R2486 T3635 T3634 pobj temozolomide,with
R2487 T3636 T3635 cc and,temozolomide
R2488 T3637 T3635 conj docetaxel,temozolomide
R2489 T3638 T3635 conj chemotherapy,temozolomide
R2490 T3639 T3640 punct ",",demonstrated
R2491 T3661 T3660 acomp important,is
R2492 T3640 T3629 ccomp demonstrated,found
R2493 T3662 T3661 prep as,important
R2494 T3663 T3665 det a,growth
R2495 T3664 T3665 compound tumor,growth
R2496 T3641 T3642 advmod more,significant
R2497 T3665 T3666 npadvmod growth,suppressing
R2498 T3666 T3662 pcomp suppressing,as
R2499 T3667 T3666 dobj cytokine,suppressing
R2500 T3642 T3644 amod significant,activity
R2501 T3668 T3657 punct .,indicate
R2502 T3669 T3670 amod NF-κB,plays
R2503 T3670 T3694 nsubjpass plays,associated
R2504 T3643 T3644 compound antitumor,activity
R2505 T3671 T3673 det a,role
R2506 T3672 T3673 amod crucial,role
R2507 T3673 T3670 dobj role,plays
R2508 T3674 T3673 prep in,role
R2509 T3675 T3676 det the,suppression
R2510 T3676 T3674 pobj suppression,in
R2511 T3677 T3676 prep of,suppression
R2512 T3644 T3640 dobj activity,demonstrated
R2513 T3678 T3677 pobj apoptosis,of
R2514 T3679 T3673 punct ",",role
R2515 T3680 T3682 advmod as,as
R2516 T3681 T3682 advmod well,as
R2517 T3645 T3644 prep against,activity
R2518 T3682 T3673 cc as,role
R2519 T3683 T3684 det the,induction
R2520 T3684 T3673 conj induction,role
R2521 T3646 T3648 compound B16,cells
R2522 T3685 T3684 prep of,induction
R2523 T3686 T3687 compound cell,proliferation
R2524 T3687 T3685 pobj proliferation,of
R2525 T3647 T3648 compound melanoma,cells
R2526 T3688 T3687 cc and,proliferation
R2527 T3689 T3687 conj inflammation,proliferation
R2528 T3690 T3670 punct ",",plays
R2529 T3648 T3645 pobj cells,against
R2530 T3691 T3670 cc and,plays
R2531 T3692 T3694 auxpass is,associated
R2532 T3693 T3694 advmod closely,associated
R2533 T3649 T3648 prep in,cells
R2534 T3694 T3694 ROOT associated,associated
R2535 T3695 T3694 prep with,associated
R2536 T3696 T3697 compound cancer,development
R2537 T3650 T3651 compound vivo,[
R2538 T3697 T3695 pobj development,with
R2539 T3698 T3700 nmod [,]
R2540 T3699 T3700 nummod 26,]
R2541 T3651 T3649 pobj [,in
R2542 T3652 T3653 nummod 25,]
R2543 T3700 T3694 npadvmod ],associated
R2544 T3653 T3651 appos ],[
R2545 T3701 T3694 punct .,associated
R2546 T3702 T3703 amod Constitutive,activation
R2547 T3654 T3629 punct .,found
R2548 T3703 T3708 nsubjpass activation,described
R2549 T3704 T3703 prep of,activation
R2550 T3705 T3704 pobj NF-κB,of
R2551 T3655 T3656 det These,data
R2552 T3706 T3708 aux has,described
R2553 T3707 T3708 auxpass been,described
R2554 T3708 T3708 ROOT described,described
R2555 T3709 T3708 prep in,described
R2556 T3710 T3712 det a,number
R2557 T3711 T3712 amod great,number
R2558 T3656 T3657 nsubj data,indicate
R2559 T3712 T3709 pobj number,in
R2560 T3713 T3712 prep of,number
R2561 T3714 T3713 pobj cancers,of
R2562 T3715 T3714 prep including,cancers
R2563 T3657 T3657 ROOT indicate,indicate
R2564 T3716 T3717 compound colon,cancers
R2565 T3717 T3715 pobj cancers,including
R2566 T3718 T3717 punct ",",cancers
R2567 T3658 T3660 mark that,is
R2568 T3719 T3720 compound prostate,cancers
R2569 T3720 T3717 conj cancers,cancers
R2570 T3721 T3720 cc and,cancers
R2571 T3659 T3660 nsubj IL-1Ra,is
R2572 T3722 T3720 conj melanoma,cancers
R2573 T3723 T3725 nmod [,]
R2574 T3724 T3725 nummod 27,]
R2575 T3660 T3657 ccomp is,indicate
R2576 T3725 T3717 appos ],cancers
R2577 T3726 T3725 punct ",",]
R2578 T3727 T3708 cc and,described
R2579 T3797 T3796 prep of,deficiency
R2580 T3798 T3799 amod various,cytokines
R2581 T3728 T3729 auxpass was,found
R2582 T3729 T3708 conj found,described
R2583 T3799 T3797 pobj cytokines,of
R2584 T3730 T3731 aux to,up-regulate
R2585 T3731 T3729 advcl up-regulate,found
R2586 T3732 T3733 compound anti-apoptotic,genes
R2587 T3800 T3799 cc and,cytokines
R2588 T3733 T3731 dobj genes,up-regulate
R2589 T3734 T3731 cc and/or,up-regulate
R2590 T3735 T3736 advmod down,regulate
R2591 T3801 T3802 compound growth,factors
R2592 T3736 T3731 conj regulate,up-regulate
R2593 T3737 T3739 amod apoptotic,expression
R2594 T3802 T3799 conj factors,cytokines
R2595 T3738 T3739 compound gene,expression
R2596 T3739 T3736 dobj expression,regulate
R2597 T3740 T3742 nmod [,]
R2598 T3803 T3799 prep in,cytokines
R2599 T3741 T3742 nummod 28,]
R2600 T3742 T3739 appos ],expression
R2601 T3804 T3805 compound T,cells
R2602 T3743 T3708 punct .,described
R2603 T3744 T3746 mark Although,promotes
R2604 T3745 T3746 nsubj NF-κB,promotes
R2605 T3746 T3752 advcl promotes,required
R2606 T3747 T3748 compound tumor,growth
R2607 T3748 T3746 dobj growth,promotes
R2608 T3749 T3752 punct ",",required
R2609 T3805 T3803 pobj cells,in
R2610 T3750 T3752 nsubjpass it,required
R2611 T3751 T3752 auxpass is,required
R2612 T3752 T3752 ROOT required,required
R2613 T3753 T3752 prep for,required
R2614 T3806 T3805 cc and,cells
R2615 T3754 T3756 det the,system
R2616 T3755 T3756 amod immune,system
R2617 T3756 T3753 pobj system,for
R2618 T3807 T3805 conj macrophages,cells
R2619 T3757 T3758 aux to,function
R2620 T3758 T3752 advcl function,required
R2621 T3759 T3760 advmod normally,[
R2622 T3760 T3762 amod [,]
R2623 T3808 T3796 acl affecting,deficiency
R2624 T3761 T3762 nummod 29,]
R2625 T3762 T3758 dobj ],function
R2626 T3763 T3752 punct .,required
R2627 T3809 T3810 preconj both,innate
R2628 T3764 T3768 nsubj Studies,demonstrated
R2629 T3765 T3764 prep on,Studies
R2630 T3766 T3767 amod c-Rel-deficient,mice
R2631 T3767 T3765 pobj mice,on
R2632 T3810 T3814 amod innate,responses
R2633 T3768 T3768 ROOT demonstrated,demonstrated
R2634 T3769 T3771 mark that,is
R2635 T3770 T3771 nsubj c-Rel,is
R2636 T3811 T3810 cc and,innate
R2637 T3771 T3768 ccomp is,demonstrated
R2638 T3772 T3771 acomp essential,is
R2639 T3773 T3771 prep for,is
R2640 T3812 T3814 amod humoral,responses
R2641 T3774 T3773 pobj IL-2,for
R2642 T3775 T3774 punct ",",IL-2
R2643 T3776 T3774 conj IL-3,IL-2
R2644 T3777 T3776 punct ",",IL-3
R2645 T3813 T3814 amod immune,responses
R2646 T3778 T3776 conj GM-CSF,IL-3
R2647 T3779 T3778 punct ",",GM-CSF
R2648 T3780 T3778 cc and,GM-CSF
R2649 T3814 T3808 dobj responses,affecting
R2650 T3781 T3782 compound IFNγ,expression
R2651 T3782 T3771 attr expression,is
R2652 T3783 T3782 prep in,expression
R2653 T3815 T3814 prep in,responses
R2654 T3784 T3785 compound T,lymphocytes
R2655 T3785 T3783 pobj lymphocytes,in
R2656 T3786 T3788 nmod [,]
R2657 T3787 T3788 nummod 30,]
R2658 T3788 T3785 appos ],lymphocytes
R2659 T3789 T3768 punct .,demonstrated
R2660 T3816 T3817 det the,host
R2661 T3790 T3791 amod C-Rel-deficient,mice
R2662 T3791 T3793 nsubj mice,have
R2663 T3792 T3793 advmod also,have
R2664 T3817 T3815 pobj host,in
R2665 T3793 T3793 ROOT have,have
R2666 T3794 T3796 det a,deficiency
R2667 T3795 T3796 amod tissue-specific,deficiency
R2668 T3818 T3817 appos [,host
R2669 T3819 T3820 nummod 31,]
R2670 T3796 T3793 dobj deficiency,have
R2671 T3820 T3817 appos ],host
R2672 T3821 T3793 punct .,have
R2673 T3822 T3828 advmod Therefore,targeted
R2674 T3823 T3828 punct ",",targeted
R2675 T3824 T3828 nsubjpass NF-κB,targeted
R2676 T3853 T3852 cc or,infiltration
R2677 T3854 T3855 punct (,3
R2678 T3825 T3828 aux can,targeted
R2679 T3855 T3857 meta 3,increasing
R2680 T3856 T3855 punct ),3
R2681 T3826 T3828 auxpass be,targeted
R2682 T3857 T3848 conj increasing,stimulating
R2683 T3858 T3859 det the,production
R2684 T3859 T3857 dobj production,increasing
R2685 T3827 T3828 advmod specially,targeted
R2686 T3860 T3859 prep of,production
R2687 T3861 T3862 nsubj tumor,killing
R2688 T3862 T3860 pcomp killing,of
R2689 T3828 T3828 ROOT targeted,targeted
R2690 T3863 T3862 dobj lymphokines,killing
R2691 T3864 T3828 punct .,targeted
R2692 T3865 T3868 nsubj Activation,is
R2693 T3866 T3865 prep of,Activation
R2694 T3829 T3830 aux to,prevent
R2695 T3867 T3866 pobj NF-κB,of
R2696 T3868 T3868 ROOT is,is
R2697 T3830 T3828 xcomp prevent,targeted
R2698 T3869 T3868 acomp important,is
R2699 T3870 T3868 prep in,is
R2700 T3871 T3872 det the,regulation
R2701 T3872 T3870 pobj regulation,in
R2702 T3831 T3832 compound cancer,cell
R2703 T3873 T3872 prep of,regulation
R2704 T3874 T3876 amod CCR-mediated,growth
R2705 T3832 T3833 compound cell,growth
R2706 T3875 T3876 compound tumor,growth
R2707 T3876 T3873 pobj growth,of
R2708 T3877 T3876 cc and,growth
R2709 T3878 T3876 conj metastasis,growth
R2710 T3879 T3868 punct .,is
R2711 T3880 T3882 nsubjpass It,reported
R2712 T3833 T3830 dobj growth,prevent
R2713 T3881 T3882 auxpass was,reported
R2714 T3882 T3882 ROOT reported,reported
R2715 T3883 T3892 mark that,induces
R2716 T3834 T3830 prep by,prevent
R2717 T3884 T3892 nsubj inhibition,induces
R2718 T3885 T3884 prep of,inhibition
R2719 T3886 T3885 pobj NF-κB,of
R2720 T3835 T3836 punct (,1
R2721 T3836 T3834 pobj 1,by
R2722 T3887 T3884 prep by,inhibition
R2723 T3837 T3836 punct ),1
R2724 T3838 T3839 advmod directly,affecting
R2725 T3888 T3887 pobj dehydroxymethyl-epoxyquinomicin,by
R2726 T3889 T3890 punct (,DHMEQ
R2727 T3890 T3888 appos DHMEQ,dehydroxymethyl-epoxyquinomicin
R2728 T3839 T3830 advcl affecting,prevent
R2729 T3891 T3884 punct ),inhibition
R2730 T3892 T3882 ccomp induces,reported
R2731 T3893 T3894 compound cell,death
R2732 T3840 T3843 amod apoptotic,death
R2733 T3894 T3892 dobj death,induces
R2734 T3895 T3894 prep of,death
R2735 T3841 T3842 compound cancer,cell
R2736 T3896 T3897 amod primary,effusion
R2737 T3897 T3898 compound effusion,lymphoma
R2738 T3898 T3895 pobj lymphoma,of
R2739 T3899 T3892 prep by,induces
R2740 T3842 T3843 compound cell,death
R2741 T3900 T3899 pobj inhibition,by
R2742 T3901 T3900 prep of,inhibition
R2743 T3902 T3906 nummod CCR5,]
R2744 T3843 T3839 dobj death,affecting
R2745 T3903 T3904 compound expression,[
R2746 T3844 T3828 punct ",",targeted
R2747 T3845 T3846 punct (,2
R2748 T3846 T3848 meta 2,stimulating
R2749 T3904 T3904 ROOT [,[
R2750 T3905 T3906 nummod 32,]
R2751 T3906 T3901 pobj ],of
R2752 T3847 T3846 punct ),2
R2753 T3907 T3882 punct .,reported
R2754 T3908 T3912 nsubj Activation,increases
R2755 T3909 T3908 prep of,Activation
R2756 T3848 T3828 advcl stimulating,targeted
R2757 T3910 T3909 pobj NF-κB,of
R2758 T3911 T3912 advmod also,increases
R2759 T3912 T3912 ROOT increases,increases
R2760 T3913 T3916 amod CCL5-mediated,motility
R2761 T3914 T3916 amod oral,motility
R2762 T3915 T3916 compound cancer,motility
R2763 T3916 T3912 dobj motility,increases
R2764 T3849 T3850 npadvmod tumor,killing
R2765 T3917 T3916 punct (,motility
R2766 T3918 T3916 appos 5,motility
R2767 T3919 T3916 punct ),motility
R2768 T3850 T3852 amod killing,infiltration
R2769 T3920 T3916 cc and,motility
R2770 T3921 T3922 compound lung,metastasis
R2771 T3922 T3923 compound metastasis,[
R2772 T3851 T3852 compound lymphocytes,infiltration
R2773 T3923 T3912 npadvmod [,increases
R2774 T3924 T3925 nummod 33,]
R2775 T3925 T3923 appos ],[
R2776 T3852 T3848 dobj infiltration,stimulating
R2777 T3926 T3912 punct .,increases
R2778 T3927 T3930 advmod Thus,is
R2779 T3959 T3956 pobj genes,of
R2780 T3928 T3930 punct ",",is
R2781 T3929 T3930 nsubj it,is
R2782 T3930 T3930 ROOT is,is
R2783 T3931 T3930 acomp possible,is
R2784 T3960 T3959 punct ",",genes
R2785 T3932 T3938 mark that,involved
R2786 T3933 T3938 nsubjpass inhibition,involved
R2787 T3934 T3933 prep of,inhibition
R2788 T3961 T3962 amod such,as
R2789 T3935 T3934 pobj NF-κB,of
R2790 T3936 T3938 aux could,involved
R2791 T3937 T3938 auxpass be,involved
R2792 T3962 T3959 prep as,genes
R2793 T3938 T3930 ccomp involved,is
R2794 T3939 T3938 prep in,involved
R2795 T3940 T3939 pobj CCR5,in
R2796 T3963 T3962 pobj IL-1alpha,as
R2797 T3941 T3930 advcl mediated,is
R2798 T3942 T3943 compound tumor,development
R2799 T3943 T3941 dobj development,mediated
R2800 T3964 T3963 punct ",",IL-1alpha
R2801 T3944 T3930 punct .,is
R2802 T3945 T3947 amod NF-κB,factor
R2803 T3946 T3947 compound transcription,factor
R2804 T3965 T3963 conj IL-6,IL-1alpha
R2805 T3947 T3947 ROOT factor,factor
R2806 T3948 T3949 amod binding,sites
R2807 T3949 T3950 nsubj sites,are
R2808 T3950 T3947 acl are,factor
R2809 T3951 T3950 acomp present,are
R2810 T3966 T3965 punct ",",IL-6
R2811 T3967 T3965 conj GM-CSF,IL-6
R2812 T3952 T3951 prep in,present
R2813 T3953 T3955 det the,region
R2814 T3954 T3955 compound promoter,region
R2815 T3968 T3967 punct ",",GM-CSF
R2816 T3955 T3952 pobj region,in
R2817 T3956 T3955 prep of,region
R2818 T3957 T3959 amod proinflammatory,genes
R2819 T3969 T3967 cc and,GM-CSF
R2820 T3958 T3959 compound cytokine,genes
R2821 T3970 T3971 compound KC,[
R2822 T3971 T3967 conj [,GM-CSF
R2823 T3972 T3973 nummod 34,]
R2824 T3973 T3971 appos ],[
R2825 T3974 T3947 punct .,factor
R2826 T4006 T3994 punct .,demonstrated
R2827 T4007 T4009 compound Smith,al.
R2828 T3975 T3982 prep On,is
R2829 T4008 T4009 compound et,al.
R2830 T4009 T4010 nsubj al.,suggested
R2831 T4010 T4010 ROOT suggested,suggested
R2832 T3976 T3978 det the,hand
R2833 T4011 T4018 mark that,is
R2834 T4012 T4013 det the,regulation
R2835 T3977 T3978 amod other,hand
R2836 T4013 T4018 nsubj regulation,is
R2837 T4014 T4013 prep of,regulation
R2838 T4015 T4017 amod IL-1Ra,expression
R2839 T3978 T3975 pobj hand,On
R2840 T4016 T4017 compound gene,expression
R2841 T4017 T4014 pobj expression,of
R2842 T4018 T4010 ccomp is,suggested
R2843 T3979 T3982 punct ",",is
R2844 T4019 T4021 det a,event
R2845 T4020 T4021 amod complex,event
R2846 T4021 T4018 attr event,is
R2847 T3980 T3981 det the,IL-1Ra
R2848 T4022 T4021 acl involving,event
R2849 T4023 T4024 det the,interactions
R2850 T4024 T4022 dobj interactions,involving
R2851 T3981 T3982 nsubj IL-1Ra,is
R2852 T4025 T4024 prep of,interactions
R2853 T4026 T4029 nummod three,factors
R2854 T3982 T3982 ROOT is,is
R2855 T4027 T4029 amod different,factors
R2856 T4028 T4029 compound transcription,factors
R2857 T4029 T4025 pobj factors,of
R2858 T4030 T4024 punct ;,interactions
R2859 T3983 T3985 det a,regulator
R2860 T4031 T4033 compound NF-κB,PU
R2861 T3984 T3985 amod negative,regulator
R2862 T4032 T4033 compound /,PU
R2863 T4033 T4035 neg PU,/
R2864 T4034 T4035 compound .1,/
R2865 T3985 T3982 attr regulator,is
R2866 T4035 T4021 appos /,event
R2867 T4036 T4039 amod GA-binding,site
R2868 T4037 T4039 nmod protein,site
R2869 T3986 T3985 prep of,regulator
R2870 T4038 T4039 amod binding,site
R2871 T4039 T4021 appos site,event
R2872 T4040 T4042 nmod [,]
R2873 T3987 T3989 det the,response
R2874 T4041 T4042 nummod 35,]
R2875 T3988 T3989 amod inflammatory,response
R2876 T3989 T3986 pobj response,of
R2877 T4042 T4039 appos ],site
R2878 T4043 T4010 punct .,suggested
R2879 T3990 T3982 punct .,is
R2880 T4044 T4045 compound Nuclear,translocation
R2881 T4045 T4053 nsubjpass translocation,enhanced
R2882 T4046 T4045 prep of,translocation
R2883 T3991 T3992 amod Several,studies
R2884 T4047 T4046 pobj NF-κB,of
R2885 T4048 T4049 punct (,p65
R2886 T3992 T3994 nsubj studies,demonstrated
R2887 T4049 T4047 appos p65,NF-κB
R2888 T4050 T4049 punct ),p65
R2889 T4051 T4053 auxpass was,enhanced
R2890 T3993 T3994 aux have,demonstrated
R2891 T4052 T4053 advmod significantly,enhanced
R2892 T4053 T4053 ROOT enhanced,enhanced
R2893 T4054 T4053 cc and,enhanced
R2894 T3994 T3994 ROOT demonstrated,demonstrated
R2895 T4055 T4053 conj prolonged,enhanced
R2896 T4056 T4055 prep in,prolonged
R2897 T4057 T4058 amod IL-1Ra-deficient,mice
R2898 T4058 T4056 pobj mice,in
R2899 T3995 T3996 det the,ability
R2900 T4059 T4055 punct ",",prolonged
R2901 T4060 T4053 prep compared,enhanced
R2902 T3996 T3994 dobj ability,demonstrated
R2903 T4061 T4060 prep to,compared
R2904 T3997 T3996 prep of,ability
R2905 T4062 T4061 pobj that,to
R2906 T3998 T3997 pobj IL-1Ra,of
R2907 T4063 T4062 prep in,that
R2908 T4064 T4066 amod wild,mice
R2909 T4065 T4066 compound type,mice
R2910 T4066 T4063 pobj mice,in
R2911 T4067 T4069 nmod [,]
R2912 T3999 T4000 aux to,abrogate
R2913 T4068 T4069 nummod 36,]
R2914 T4069 T4066 appos ],mice
R2915 T4070 T4053 punct .,enhanced
R2916 T4000 T3996 acl abrogate,ability
R2917 T4071 T4072 amod Intracellular,IL-1Ra
R2918 T4072 T4077 nsubjpass IL-1Ra,found
R2919 T4073 T4074 punct (,icIL-1Ra
R2920 T4074 T4072 appos icIL-1Ra,IL-1Ra
R2921 T4001 T4003 det the,effects
R2922 T4075 T4074 punct ),icIL-1Ra
R2923 T4076 T4077 auxpass was,found
R2924 T4077 T4077 ROOT found,found
R2925 T4002 T4003 amod proinflammatory,effects
R2926 T4078 T4079 aux to,inhibit
R2927 T4079 T4077 advcl inhibit,found
R2928 T4080 T4079 dobj IL-1,inhibit
R2929 T4003 T4000 dobj effects,abrogate
R2930 T4081 T4079 prep by,inhibit
R2931 T4082 T4081 pcomp blocking,by
R2932 T4083 T4086 amod NF-κB,pathways
R2933 T4004 T4003 prep of,effects
R2934 T4084 T4086 nmod signal,pathways
R2935 T4085 T4086 compound transduction,pathways
R2936 T4086 T4082 dobj pathways,blocking
R2937 T4005 T4004 pobj IL-1,of
R2938 T4103 T4102 prep of,inducer
R2939 T4087 T4086 prep in,pathways
R2940 T4088 T4089 amod inflammatory,responses
R2941 T4089 T4087 pobj responses,in
R2942 T4090 T4092 nmod [,]
R2943 T4104 T4105 amod NF-κB,activation
R2944 T4091 T4092 nummod 37,]
R2945 T4092 T4086 conj ],pathways
R2946 T4093 T4077 punct .,found
R2947 T4105 T4103 pobj activation,of
R2948 T4094 T4098 mark Because,shown
R2949 T4095 T4098 nsubjpass IL-1,shown
R2950 T4096 T4098 aux has,shown
R2951 T4097 T4098 auxpass been,shown
R2952 T4106 T4108 nmod [,]
R2953 T4098 T4111 advcl shown,hypothesized
R2954 T4099 T4100 aux to,be
R2955 T4100 T4098 xcomp be,shown
R2956 T4107 T4108 nummod 38,]
R2957 T4101 T4102 det an,inducer
R2958 T4102 T4100 attr inducer,be
R2959 T4108 T4102 appos ],inducer
R2960 T4109 T4111 punct ",",hypothesized
R2961 T4110 T4111 nsubj we,hypothesized
R2962 T4111 T4111 ROOT hypothesized,hypothesized
R2963 T4112 T4118 mark that,play
R2964 T4113 T4114 det the,expression
R2965 T4114 T4118 nsubj expression,play
R2966 T4115 T4114 prep of,expression
R2969 T4116 T4115 pobj IL-1Ra,of
R2973 T4117 T4118 aux could,play
R2976 T4118 T4111 ccomp play,hypothesized
R2977 T4119 T4121 det an,role
R2978 T4120 T4121 amod important,role
R2979 T4121 T4118 dobj role,play
R2980 T4122 T4118 prep in,play
R2981 T4123 T4125 det the,activation
R2984 T4124 T4125 compound autocrine,activation
R2985 T4125 T4122 pobj activation,in
R2997 T4126 T4125 prep of,activation
R3001 T4127 T4128 compound transcription,factors
R3002 T4128 T4126 pobj factors,of
R3003 T4129 T4118 conj NF-κB,play
R3004 T4130 T4129 cc or,NF-κB
R3005 T4131 T4132 advmod vice,versa
R3006 T4132 T4129 conj versa,NF-κB
R3009 T4133 T4111 punct .,hypothesized
R3012 T4134 T4141 advmod Thus,was
R3013 T4135 T4141 punct ",",was
R3014 T4136 T4137 det the,aim
R3015 T4137 T4141 nsubj aim,was
R3017 T4138 T4137 prep of,aim
R3021 T4139 T4140 det this,study
R3024 T4140 T4138 pobj study,of
R3026 T4141 T4141 ROOT was,was
R3027 T4142 T4143 aux to,evaluate
R3028 T4143 T4141 xcomp evaluate,was
R3029 T4144 T4145 det the,roles
R3030 T4145 T4143 dobj roles,evaluate
R3031 T4146 T4145 prep of,roles
R3032 T4147 T4146 pobj NF-κB,of
R3034 T4148 T4147 cc and,NF-κB
R3035 T4149 T4147 conj IL-1Ra,NF-κB
R3037 T4150 T4145 prep in,roles
R3039 T4151 T4155 det the,suppression
R3040 T4152 T4155 nmod chemokine,suppression
R3042 T4153 T4155 nmod receptor,suppression
R3043 T4154 T4155 amod CCR5-mediated,suppression
R3046 T4155 T4150 pobj suppression,in
R3047 T4156 T4155 prep of,suppression
R3048 T4157 T4158 compound tumor,development
R3049 T4158 T4156 pobj development,of
R3050 T4159 T4141 punct .,was
R3336 T4871 T4872 nummod 19.1,%
R3337 T4872 T5352 pobj %,to
R3338 T4873 T5351 punct ",",reduced
R3339 T4874 T4882 mark whereas,/
R3340 T4875 T4877 det the,growth
R3341 T4876 T4877 compound tumor,growth
R3342 T4877 T4882 nsubj growth,/
R3343 T4878 T4877 prep in,growth
R3344 T4879 T4881 det the,+
R3345 T4880 T4881 compound CCR5,+
R3346 T4881 T4878 pobj +,in
R3347 T4882 T5351 advcl /,reduced
R3348 T4883 T4884 nummod +,mice
R3349 T4884 T4882 dobj mice,/
R3350 T4885 T4887 auxpass was,reduced
R3351 T4886 T4887 advmod only,reduced
R3352 T4887 T5351 conj reduced,reduced
R3353 T4888 T4887 prep to,reduced
R3354 T4889 T4890 nummod 24.3,%
R3355 T4890 T4888 pobj %,to
R3356 T4891 T4887 punct ",",reduced
R3357 T4892 T4887 prep in,reduced
R3358 T4893 T4895 det both,weight
R3359 T4894 T4895 compound tumor,weight
R3360 T4895 T4892 pobj weight,in
R3361 T4896 T4897 punct (,Figure
R3362 T4897 T4904 nmod Figure,volume
R3363 T4898 T4897 nummod 1A,Figure
R3364 T4899 T4897 cc and,Figure
R3365 T4900 T4897 conj 1B,Figure
R3366 T4901 T4900 punct ),1B
R3367 T4902 T4900 cc and,1B
R3368 T4903 T4904 compound tumor,volume
R3369 T4904 T4887 dobj volume,reduced
R3370 T4905 T4887 punct ",",reduced
R3371 T4906 T4887 advmod respectively,reduced
R3372 T4907 T4908 punct (,Figure
R3373 T4908 T4887 appos Figure,reduced
R3374 T4909 T4908 nummod 1A,Figure
R3375 T4910 T4908 cc and,Figure
R3376 T4911 T4908 conj 1C,Figure
R3377 T4912 T4908 punct ),Figure
R3378 T4913 T5351 punct .,reduced
R3379 T4914 T4915 det These,results
R3380 T4915 T4915 ROOT results,results
R3381 T4916 T4915 acl correlated,results
R3382 T4917 T4916 prep with,correlated
R3383 T4918 T4920 nmod mice,rates
R3384 T4919 T4920 compound survival,rates
R3385 T4920 T4917 pobj rates,with
R3386 T4921 T4915 punct .,results
R3387 T4922 T4923 expl There,was
R3388 T4923 T4923 ROOT was,was
R3389 T4924 T4926 det a,difference
R3390 T4925 T4926 amod significant,difference
R3391 T4926 T4923 attr difference,was
R3392 T4927 T4926 prep in,difference
R3393 T4928 T4929 compound survival,rates
R3394 T4929 T4927 pobj rates,in
R3395 T4930 T4926 prep between,difference
R3396 T4931 T4935 nummod CCR5,mice
R3397 T4932 T4935 nummod −,mice
R3398 T4933 T4935 compound /,mice
R3399 T4934 T4935 compound −,mice
R3400 T4935 T4930 pobj mice,between
R3401 T4936 T4935 punct (,mice
R3402 T4937 T4938 nummod 75,%
R3403 T4938 T4935 appos %,mice
R3404 T4939 T4938 prep of,%
R3405 T4940 T4941 compound starting,time
R3406 T4941 T4939 pobj time,of
R3407 T4942 T4935 punct ),mice
R3408 T4943 T4935 cc and,mice
R3409 T4944 T4948 nummod CCR5,mice
R3410 T4945 T4948 nummod +,mice
R3411 T4946 T4948 compound /,mice
R3412 T4947 T4948 compound +,mice
R3413 T4948 T4935 conj mice,mice
R3414 T4949 T4926 punct (,difference
R3415 T4950 T4951 nummod 15,%
R3416 T4951 T4926 appos %,difference
R3417 T4952 T4926 punct ),difference
R3418 T4953 T4923 prep at,was
R3419 T4954 T4955 det the,end
R3420 T4955 T4953 pobj end,at
R3421 T4956 T4955 prep of,end
R3422 T4957 T4958 det the,experiment
R3423 T4958 T4956 pobj experiment,of
R3424 T4959 T4960 punct (,Figure
R3425 T4960 T4958 appos Figure,experiment
R3426 T4961 T4960 nummod 1D,Figure
R3427 T4962 T4960 punct ),Figure
R3428 T4963 T4923 punct .,was
R3429 T4964 T4965 expl There,was
R3430 T4965 T4965 ROOT was,was
R3431 T4966 T4968 det a,difference
R3432 T4967 T4968 amod significant,difference
R3433 T4968 T4965 attr difference,was
R3434 T4969 T4968 prep in,difference
R3435 T4970 T4971 compound survival,rates
R3436 T4971 T4969 pobj rates,in
R3437 T4972 T4968 prep between,difference
R3438 T4973 T4977 nummod CCR5,mice
R3439 T4974 T4977 nummod −,mice
R3440 T4975 T4977 nmod /,mice
R3441 T4976 T4977 compound −,mice
R3442 T4977 T4972 pobj mice,between
R3443 T4978 T4977 cc and,mice
R3444 T4979 T4977 conj CCR5,mice
R3445 T4980 T4965 attr +,was
R3446 T4981 T4983 nummod /,mice
R3447 T4982 T4983 nummod +,mice
R3448 T4983 T4980 dobj mice,+
R3449 T4984 T4965 punct .,was
R3450 T4985 T4998 prep At,/
R3451 T4986 T4987 det the,end
R3452 T4987 T4985 pobj end,At
R3453 T4988 T4987 prep of,end
R3454 T4989 T4990 det the,experiment
R3455 T4990 T4988 pobj experiment,of
R3456 T4991 T4998 punct ",",/
R3457 T4992 T4993 nummod 75,%
R3458 T4993 T4998 nsubj %,/
R3459 T4994 T4993 prep of,%
R3460 T4995 T4997 det the,−
R3461 T4996 T4997 compound CCR5,−
R3462 T4997 T4994 pobj −,of
R3463 T4998 T4998 ROOT /,/
R3464 T4999 T5000 nummod −,mice
R3465 T5000 T4998 dobj mice,/
R3466 T5001 T4998 conj survived,/
R3467 T5002 T5010 mark while,/
R3468 T5003 T5004 advmod only,15
R3469 T5004 T5005 nummod 15,%
R3470 T5005 T5010 nsubj %,/
R3471 T5006 T5005 prep of,%
R3472 T5007 T5009 det the,+
R3473 T5008 T5009 compound CCR5,+
R3474 T5009 T5006 pobj +,of
R3475 T5010 T5001 advcl /,survived
R3476 T5011 T5012 nummod +,mice
R3477 T5012 T5010 dobj mice,/
R3478 T5013 T5001 conj survived,survived
R3479 T5014 T4998 punct .,/
R3480 T5015 T5016 amod Subcutaneous,tumors
R3481 T5016 T5018 nsubjpass tumors,harvested
R3482 T5017 T5018 auxpass were,harvested
R3483 T5018 T5018 ROOT harvested,harvested
R3484 T5019 T5018 prep from,harvested
R3485 T5020 T5022 det the,mice
R3486 T5021 T5022 amod sacrificed,mice
R3487 T5022 T5019 pobj mice,from
R3488 T5023 T5024 nummod 31,days
R3489 T5024 T5025 npadvmod days,after
R3490 T5025 T5022 prep after,mice
R3491 T5026 T5025 pobj inoculation,after
R3492 T5027 T5018 punct .,harvested
R3493 T5028 T5030 det The,analysis
R3494 T5029 T5030 amod immunohistochemical,analysis
R3495 T5030 T5044 nsubj analysis,revealed
R3496 T5031 T5030 prep of,analysis
R3497 T5032 T5033 compound tumor,sections
R3498 T5033 T5031 pobj sections,of
R3499 T5034 T5030 punct ",",analysis
R3500 T5035 T5030 acl stained,analysis
R3501 T5036 T5035 prep with,stained
R3502 T5037 T5036 pobj H&E,with
R3503 T5038 T5035 cc and,stained
R3504 T5039 T5044 prep for,revealed
R3505 T5040 T5041 compound proliferation,antigen
R3506 T5041 T5039 pobj antigen,for
R3507 T5042 T5039 pobj PCNA,for
R3508 T5043 T5044 punct ",",revealed
R3509 T5044 T5044 ROOT revealed,revealed
R3510 T5045 T5046 amod greater,inhibition
R3511 T5046 T5044 dobj inhibition,revealed
R3512 T5047 T5046 prep of,inhibition
R3513 T5048 T5049 compound tumor,cell
R3514 T5049 T5050 compound cell,growth
R3515 T5050 T5047 pobj growth,of
R3516 T5051 T5044 prep in,revealed
R3517 T5052 T5056 nummod CCR5,mice
R3518 T5053 T5056 nummod −,mice
R3519 T5054 T5056 nmod /,mice
R3520 T5055 T5056 compound −,mice
R3521 T5056 T5051 pobj mice,in
R3522 T5057 T5044 punct .,revealed
R3523 T5058 T5060 det The,findings
R3524 T5059 T5060 amod histologic,findings
R3525 T5060 T5064 nsubj findings,indicated
R3526 T5061 T5064 mark after,indicated
R3527 T5062 T5064 nsubj H&E,indicated
R3528 T5063 T5064 auxpass staining,indicated
R3529 T5064 T5064 ROOT indicated,indicated
R3530 T5065 T5073 mark that,/
R3531 T5066 T5068 det the,tissues
R3532 T5067 T5068 compound tumor,tissues
R3533 T5068 T5073 nsubj tissues,/
R3534 T5069 T5068 prep of,tissues
R3535 T5070 T5072 det the,−
R3536 T5071 T5072 compound CCR5,−
R3537 T5072 T5069 pobj −,of
R3538 T5073 T5064 ccomp /,indicated
R3539 T5074 T5075 nummod −,mice
R3540 T5075 T5073 dobj mice,/
R3541 T5076 T5073 punct ",",/
R3542 T5077 T5073 cc but,/
R3543 T5078 T5079 neg not,those
R3544 T5079 T5084 nsubj those,/
R3545 T5080 T5079 prep of,those
R3546 T5081 T5083 det the,+
R3547 T5082 T5083 compound CCR5,+
R3548 T5083 T5080 pobj +,of
R3549 T5084 T5073 conj /,/
R3550 T5085 T5086 nummod +,mice
R3551 T5086 T5084 dobj mice,/
R3552 T5087 T5084 punct ",",/
R3553 T5088 T5084 conj contained,/
R3554 T5089 T5090 amod large,areas
R3555 T5090 T5088 dobj areas,contained
R3556 T5091 T5090 prep of,areas
R3557 T5092 T5091 pobj necrosis,of
R3558 T5093 T5064 punct .,indicated
R3559 T5094 T5096 amod PCNA,cells
R3560 T5095 T5096 amod reactive,cells
R3561 T5096 T5099 nsubjpass cells,reduced
R3562 T5097 T5099 auxpass were,reduced
R3563 T5098 T5099 advmod significantly,reduced
R3564 T5099 T5099 ROOT reduced,reduced
R3565 T5100 T5099 prep in,reduced
R3566 T5101 T5103 det the,−
R3567 T5102 T5103 compound CCR5,−
R3568 T5103 T5100 pobj −,in
R3569 T5104 T5099 advcl /,reduced
R3570 T5105 T5106 nummod −,mice
R3571 T5106 T5104 dobj mice,/
R3572 T5107 T5108 punct (,Figure
R3573 T5108 T5106 appos Figure,mice
R3574 T5109 T5108 nummod 1E,Figure
R3575 T5110 T5108 punct ),Figure
R3576 T5111 T5099 punct .,reduced
R3579 T5228 T5235 nsubj Inhibition,/
R3580 T5229 T5228 prep of,Inhibition
R3581 T5230 T5231 compound Tumor,Development
R3582 T5231 T5229 pobj Development,of
R3583 T5232 T5228 prep in,Inhibition
R3584 T5233 T5234 compound CCR5,−
R3585 T5234 T5232 pobj −,in
R3586 T5235 T5235 ROOT /,/
R3587 T5236 T5235 npadvmod −,/
R3588 T5237 T5237 ROOT Mice,Mice
R3589 T5238 T5239 det The,effect
R3590 T5239 T5246 nsubjpass effect,investigated
R3591 T5240 T5239 prep of,effect
R3592 T5241 T5240 pobj CCR5,of
R3593 T5242 T5239 prep in,effect
R3594 T5243 T5244 compound tumor,development
R3595 T5244 T5242 pobj development,in
R3596 T5245 T5246 auxpass was,investigated
R3597 T5246 T5246 ROOT investigated,investigated
R3598 T5247 T5246 advcl using,investigated
R3599 T5248 T5249 compound CCR5,+
R3600 T5249 T5257 nmod +,mice
R3601 T5250 T5257 nmod /,mice
R3602 T5251 T5250 npadvmod +,/
R3603 T5252 T5251 cc and,+
R3604 T5253 T5257 nummod CCR5,mice
R3605 T5254 T5257 nummod −,mice
R3606 T5255 T5257 nmod /,mice
R3607 T5256 T5257 compound −,mice
R3608 T5257 T5247 dobj mice,using
R3609 T5258 T5246 punct .,investigated
R3610 T5259 T5261 nummod B16-F0,cells
R3611 T5260 T5261 compound melanoma,cells
R3612 T5261 T5263 nsubjpass cells,inoculated
R3613 T5262 T5263 auxpass were,inoculated
R3614 T5263 T5263 ROOT inoculated,inoculated
R3615 T5264 T5263 advmod subcutaneously,inoculated
R3616 T5265 T5263 prep into,inoculated
R3617 T5266 T5269 nummod CCR5,+
R3618 T5267 T5269 nummod +,+
R3619 T5268 T5269 compound /,+
R3620 T5269 T5265 pobj +,into
R3621 T5270 T5269 cc and,+
R3622 T5271 T5272 nummod CCR5,−
R3623 T5272 T5273 nummod −,/
R3624 T5273 T5275 compound /,mice
R3625 T5274 T5275 compound −,mice
R3626 T5275 T5269 conj mice,+
R3627 T5276 T5275 punct (,mice
R3628 T5277 T5280 nmod n,)
R3629 T5278 T5279 punct =,20
R3630 T5279 T5277 prep 20,n
R3631 T5280 T5275 punct ),mice
R3632 T5281 T5263 punct .,inoculated
R3633 T5282 T5283 compound Tumor,growth
R3634 T5283 T5285 nsubjpass growth,monitored
R3635 T5284 T5285 auxpass was,monitored
R3636 T5285 T5285 ROOT monitored,monitored
R3637 T5286 T5285 prep for,monitored
R3638 T5287 T5288 nummod 31,days
R3639 T5288 T5286 pobj days,for
R3640 T5289 T5285 punct .,monitored
R3641 T5290 T5291 compound Tumor,growth
R3642 T5291 T5296 nsubj growth,/
R3643 T5292 T5291 prep in,growth
R3644 T5293 T5295 det the,−
R3645 T5294 T5295 compound CCR5,−
R3646 T5295 T5292 pobj −,in
R3647 T5296 T5296 ROOT /,/
R3648 T5297 T5298 nummod −,mice
R3649 T5298 T5296 dobj mice,/
R3650 T5299 T5296 conj was,/
R3651 T5300 T5301 advmod significantly,lower
R3652 T5301 T5299 acomp lower,was
R3653 T5302 T5301 prep than,lower
R3654 T5303 T5302 pobj that,than
R3655 T5304 T5303 prep in,that
R3656 T5305 T5307 det the,+
R3657 T5306 T5307 compound CCR5,+
R3658 T5307 T5304 pobj +,in
R3659 T5308 T5299 conj /,was
R3660 T5309 T5310 nummod +,mice
R3661 T5310 T5308 dobj mice,/
R3662 T5311 T5296 punct .,/
R3663 T5312 T5314 det The,growth
R3664 T5313 T5314 compound tumor,growth
R3665 T5314 T5319 nsubj growth,/
R3666 T5315 T5314 prep in,growth
R3667 T5316 T5318 det the,−
R3668 T5317 T5318 compound CCR5,−
R3669 T5318 T5315 pobj −,in
R3670 T5319 T5319 ROOT /,/
R3671 T5320 T5321 nummod −,mice
R3672 T5321 T5351 nsubjpass mice,reduced
R3673 T5322 T5351 auxpass was,reduced
R3674 T5351 T5319 conj reduced,/
R3675 T5352 T5351 prep to,reduced
R3845 T5636 T5646 nsubj Decrease,/
R3846 T5637 T5636 prep of,Decrease
R3847 T5638 T5639 compound NF-κB,Activity
R3848 T5639 T5637 pobj Activity,of
R3849 T5640 T5639 prep in,Activity
R3850 T5641 T5642 compound Tumor,Tissue
R3851 T5642 T5640 pobj Tissue,in
R3852 T5643 T5642 prep of,Tissue
R3853 T5644 T5645 compound CCR5,−
R3854 T5645 T5643 pobj −,of
R3855 T5646 T5646 ROOT /,/
R3856 T5647 T5646 npadvmod −,/
R3857 T5648 T5648 ROOT Mice,Mice
R3858 T5649 T5650 det The,activation
R3859 T5650 T5650 ROOT activation,activation
R3860 T5651 T5650 prep of,activation
R3861 T5652 T5653 amod NF-κB,plays
R3862 T5653 T5651 pobj plays,of
R3863 T5654 T5656 det a,role
R3864 T5655 T5656 amod critical,role
R3865 T5656 T5650 conj role,activation
R3866 T5657 T5656 prep in,role
R3867 T5658 T5659 compound cancer,cell
R3868 T5659 T5660 compound cell,survival
R3869 T5660 T5657 pobj survival,in
R3870 T5661 T5657 punct ",",in
R3871 T5662 T5665 advmod especially,cells
R3872 T5663 T5665 compound melanoma,cells
R3873 T5664 T5665 compound cancer,cells
R3874 T5665 T5656 appos cells,role
R3875 T5666 T5650 cc and,activation
R3876 T5667 T5650 prep in,activation
R3877 T5668 T5669 amod CCR5,expression
R3878 T5669 T5667 pobj expression,in
R3879 T5670 T5650 punct .,activation
R3880 T5671 T5672 aux To,evaluate
R3881 T5672 T5694 advcl evaluate,determined
R3882 T5673 T5678 mark whether,related
R3883 T5674 T5676 det the,inhibition
R3884 T5675 T5676 compound tumor,inhibition
R3885 T5676 T5678 nsubjpass inhibition,related
R3886 T5677 T5678 auxpass was,related
R3887 T5678 T5672 advcl related,evaluate
R3888 T5679 T5678 prep with,related
R3889 T5680 T5681 det the,inactivation
R3890 T5681 T5679 pobj inactivation,with
R3891 T5682 T5681 prep of,inactivation
R3892 T5683 T5682 pobj NF-κB,of
R3893 T5684 T5681 prep in,inactivation
R3894 T5685 T5684 pobj melanoma,in
R3895 T5686 T5681 punct ",",inactivation
R3896 T5687 T5690 det the,activity
R3897 T5688 T5690 compound DNA,activity
R3898 T5689 T5690 amod binding,activity
R3899 T5690 T5681 conj activity,inactivation
R3900 T5691 T5690 prep of,activity
R3901 T5692 T5691 pobj NF-κB,of
R3902 T5693 T5694 auxpass was,determined
R3903 T5694 T5694 ROOT determined,determined
R3904 T5695 T5694 agent by,determined
R3905 T5696 T5698 compound electromobility,assay
R3906 T5697 T5698 compound shift,assay
R3907 T5698 T5695 pobj assay,by
R3908 T5699 T5698 punct (,assay
R3909 T5700 T5698 appos EMSA,assay
R3910 T5701 T5698 punct ),assay
R3911 T5702 T5694 prep in,determined
R3912 T5703 T5704 compound melanoma,tissue
R3913 T5704 T5702 pobj tissue,in
R3914 T5705 T5694 punct .,determined
R3915 T5706 T5711 det The,activity
R3916 T5707 T5708 advmod constitutively,activated
R3917 T5708 T5711 amod activated,activity
R3918 T5709 T5711 amod DNA,activity
R3919 T5710 T5711 amod binding,activity
R3920 T5711 T5713 nsubjpass activity,reduced
R3921 T5712 T5713 auxpass was,reduced
R3922 T5713 T5713 ROOT reduced,reduced
R3923 T5714 T5713 prep in,reduced
R3924 T5715 T5717 det the,−
R3925 T5716 T5717 compound CCR5,−
R3926 T5717 T5714 pobj −,in
R3927 T5718 T5713 advcl /,reduced
R3928 T5719 T5720 nummod −,mice
R3929 T5720 T5725 compound mice,2A
R3930 T5721 T5722 compound tumor,tissue
R3931 T5722 T5725 compound tissue,2A
R3932 T5723 T5724 punct (,Figure
R3933 T5724 T5725 compound Figure,2A
R3934 T5725 T5718 dobj 2A,/
R3935 T5726 T5713 punct ),reduced
R3936 T5727 T5713 punct .,reduced
R3937 T5728 T5748 advmod Moreover,prevented
R3938 T5729 T5748 punct ",",prevented
R3939 T5730 T5731 det the,translocation
R3940 T5731 T5748 nsubjpass translocation,prevented
R3941 T5732 T5731 prep of,translocation
R3942 T5733 T5732 pobj p50,of
R3943 T5734 T5733 cc and,p50
R3944 T5735 T5733 conj p-p65,p50
R3945 T5736 T5731 prep into,translocation
R3946 T5737 T5738 det the,nucleus
R3947 T5738 T5736 pobj nucleus,into
R3948 T5739 T5731 prep through,translocation
R3949 T5740 T5741 det the,inhibition
R3950 T5741 T5739 pobj inhibition,through
R3951 T5742 T5741 prep of,inhibition
R3952 T5743 T5742 pobj phosphorylation,of
R3953 T5744 T5743 prep of,phosphorylation
R3954 T5745 T5744 pobj IκB,of
R3955 T5746 T5748 auxpass was,prevented
R3956 T5747 T5748 advmod also,prevented
R3957 T5748 T5748 ROOT prevented,prevented
R3958 T5749 T5748 prep in,prevented
R3959 T5750 T5752 det the,tissues
R3960 T5751 T5752 compound tumor,tissues
R3961 T5752 T5749 pobj tissues,in
R3962 T5753 T5752 prep of,tissues
R3963 T5754 T5758 nummod CCR5,mice
R3964 T5755 T5758 nummod −,mice
R3965 T5756 T5758 nmod /,mice
R3966 T5757 T5758 compound −,mice
R3967 T5758 T5753 pobj mice,of
R3968 T5759 T5761 punct (,2B
R3969 T5760 T5761 compound Figure,2B
R3970 T5761 T5758 appos 2B,mice
R3971 T5762 T5748 punct ),prevented
R3972 T5763 T5748 punct .,prevented
R3973 T5764 T5765 compound Immunofluorescence,analysis
R3974 T5765 T5767 nsubj analysis,confirmed
R3975 T5766 T5767 advmod also,confirmed
R3976 T5767 T5767 ROOT confirmed,confirmed
R3977 T5768 T5777 mark that,decreased
R3978 T5769 T5770 det the,intensity
R3979 T5770 T5777 nsubj intensity,decreased
R3980 T5771 T5770 prep of,intensity
R3981 T5772 T5773 amod nuclear,staining
R3982 T5773 T5771 pobj staining,of
R3983 T5774 T5770 prep for,intensity
R3984 T5775 T5774 pobj p50,for
R3985 T5776 T5777 aux had,decreased
R3986 T5777 T5767 ccomp decreased,confirmed
R3987 T5778 T5777 prep in,decreased
R3988 T5779 T5781 det the,tissues
R3989 T5780 T5781 compound tumor,tissues
R3990 T5781 T5778 pobj tissues,in
R3991 T5782 T5781 prep of,tissues
R3992 T5783 T5787 nummod CCR5,mice
R3993 T5784 T5787 nummod −,mice
R3994 T5785 T5787 nmod /,mice
R3995 T5786 T5787 compound −,mice
R3996 T5787 T5782 pobj mice,of
R3997 T5788 T5789 punct (,Figure
R3998 T5789 T5781 appos Figure,tissues
R3999 T5790 T5789 npadvmod 2C,Figure
R4000 T5791 T5789 punct ),Figure
R4001 T5792 T5767 punct .,confirmed
R425 T820 T820 ROOT Deficiency,Deficiency
R4259 T6287 T6326 nmod Induction,Mice
R426 T821 T820 prep of,Deficiency
R4260 T6288 T6287 prep of,Induction
R4261 T6289 T6291 compound Apoptotic,Death
R4262 T6290 T6291 compound Cell,Death
R4263 T6291 T6288 pobj Death,of
R4264 T6292 T6291 cc and,Death
R4265 T6293 T6291 conj Inhibition,Death
R4266 T6294 T6293 prep of,Inhibition
R4267 T6295 T6296 det the,Expression
R4268 T6296 T6294 pobj Expression,of
R4269 T6297 T6296 prep of,Expression
R427 T822 T824 compound C-C,Receptor
R4270 T6298 T6299 amod Anti-apoptotic,Proteins
R4271 T6299 T6297 pobj Proteins,of
R4272 T6300 T6296 prep in,Expression
R4273 T6301 T6302 compound CCR5,−
R4274 T6302 T6300 pobj −,in
R4275 T6303 T6326 nmod /,Mice
R4276 T6304 T6326 nummod −,Mice
R428 T823 T824 compound Chemokine,Receptor
R4287 T6326 T6326 ROOT Mice,Mice
R4288 T6327 T6328 aux To,see
R4289 T6328 T6328 ROOT see,see
R429 T824 T821 pobj Receptor,of
R4290 T6329 T6368 mark whether,assessed
R4291 T6330 T6368 nsubjpass inhibition,assessed
R4292 T6331 T6330 prep of,inhibition
R4293 T6332 T6334 amod NF-κB,results
R4294 T6333 T6334 compound activity,results
R4295 T6334 T6331 pobj results,of
R4296 T6335 T6334 prep in,results
R4297 T6336 T6337 det the,induction
R4298 T6337 T6335 pobj induction,in
R4299 T6338 T6337 prep of,induction
R430 T825 T826 nummod 5,Suppresses
R4300 T6339 T6341 amod apoptotic,death
R4301 T6340 T6341 compound cell,death
R4302 T6341 T6338 pobj death,of
R4303 T6342 T6341 cc and,death
R4304 T6343 T6341 conj expression,death
R4305 T6344 T6343 prep of,expression
R4306 T6345 T6346 amod NF-κB,target
R4307 T6346 T6351 nmod target,protein
R4308 T6347 T6351 amod apoptotic,protein
R4309 T6348 T6349 compound cell,death
R431 T826 T828 compound Suppresses,Development via Inactivation
R4310 T6349 T6351 nmod death,protein
R4311 T6350 T6351 amod regulatory,protein
R4312 T6351 T6344 pobj protein,of
R4313 T6352 T6368 punct ",",assessed
R4314 T6353 T6354 det the,levels
R4315 T6354 T6368 nsubjpass levels,assessed
R4316 T6355 T6354 prep of,levels
R4317 T6356 T6358 amod apoptotic,death
R4318 T6357 T6358 compound cell,death
R4319 T6358 T6355 pobj death,of
R432 T827 T828 compound Tumor,Development via Inactivation
R4320 T6359 T6358 cc and,death
R4321 T6360 T6358 conj expression,death
R4322 T6361 T6360 prep of,expression
R4323 T6362 T6366 amod apoptotic,proteins
R4324 T6363 T6364 compound cell,death
R4325 T6364 T6366 nmod death,proteins
R4326 T6365 T6366 amod regulatory,proteins
R4327 T6366 T6361 pobj proteins,of
R4328 T6367 T6368 auxpass were,assessed
R4329 T6368 T6328 ccomp assessed,see
R433 T828 T820 conj Development via Inactivation,Deficiency
R4330 T6369 T6328 punct .,see
R4331 T6370 T6372 amod Apoptotic,death
R4332 T6371 T6372 compound cell,death
R4333 T6372 T6378 nsubjpass death,evaluated
R4334 T6373 T6372 prep in,death
R4335 T6374 T6376 det the,sections
R4336 T6375 T6376 compound tumor,sections
R4337 T6376 T6373 pobj sections,in
R4338 T6377 T6378 auxpass were,evaluated
R4339 T6378 T6378 ROOT evaluated,evaluated
R434 T829 T828 prep of,Development via Inactivation
R4340 T6379 T6378 prep in,evaluated
R4341 T6380 T6382 det the,+
R4342 T6381 T6382 compound CCR5,+
R4343 T6382 T6379 pobj +,in
R4344 T6383 T6378 advcl /,evaluated
R4345 T6384 T6390 nummod +,mice
R4346 T6385 T6384 cc and,+
R4347 T6386 T6390 nummod CCR5,mice
R4348 T6387 T6390 nummod −,mice
R4349 T6388 T6390 nmod /,mice
R435 T830 T829 pobj NF,of
R4350 T6389 T6390 compound −,mice
R4351 T6390 T6383 dobj mice,/
R4352 T6391 T6417 nsubjpass that,inoculated
R4355 T6416 T6417 auxpass were,inoculated
R4356 T6417 T6390 relcl inoculated,mice
R4357 T6418 T6417 prep with,inoculated
R4358 T6419 T6420 compound melanoma,cells
R4359 T6420 T6418 pobj cells,with
R436 T831 T828 punct -,Development via Inactivation
R4360 T6421 T6378 punct .,evaluated
R4361 T6422 T6424 nsubj TUNEL,revealed
R4362 T6423 T6424 nsubj staining,revealed
R4363 T6424 T6424 ROOT revealed,revealed
R4364 T6425 T6427 det a,frequency
R4365 T6426 T6427 amod higher,frequency
R4366 T6427 T6424 dobj frequency,revealed
R4367 T6428 T6427 prep of,frequency
R4368 T6429 T6431 amod apoptotic,death
R4369 T6430 T6431 compound cell,death
R437 T832 T828 punct κ,Development via Inactivation
R4370 T6431 T6428 pobj death,of
R4371 T6432 T6427 prep in,frequency
R4372 T6433 T6435 det the,tissues
R4373 T6434 T6435 compound tumor,tissues
R4374 T6435 T6432 pobj tissues,in
R4375 T6436 T6435 prep of,tissues
R4376 T6437 T6439 det the,−
R4377 T6438 T6439 compound CCR5,−
R4378 T6439 T6436 pobj −,of
R4379 T6440 T6424 conj /,revealed
R438 T833 T860 advcl B,compared
R4380 T6441 T6442 nummod −,mice
R4381 T6442 T6440 dobj mice,/
R4382 T6443 T6442 prep than,mice
R4383 T6444 T6443 pobj that,than
R4384 T6445 T6444 prep of,that
R4385 T6446 T6448 det the,+
R4386 T6447 T6448 compound CCR5,+
R4387 T6448 T6445 pobj +,of
R4388 T6449 T6440 conj /,/
R4389 T6450 T6451 nummod +,mice
R439 T834 T833 cc and,B
R4390 T6451 T6449 dobj mice,/
R4391 T6452 T6454 punct (,3A
R4392 T6453 T6454 compound Figure,3A
R4393 T6454 T6451 appos 3A,mice
R4394 T6455 T6451 punct ),mice
R4395 T6456 T6424 punct .,revealed
R4396 T6457 T6460 nsubj Immunohistochemical,showed
R4397 T6458 T6457 cc and,Immunohistochemical
R4398 T6459 T6457 conj immunofluorescence,Immunohistochemical
R4399 T6460 T6460 ROOT showed,showed
R440 T835 T833 conj Upregulation,B
R4400 T6461 T6470 mark that,found
R4401 T6462 T6463 amod high,levels
R4402 T6463 T6470 nsubjpass levels,found
R4403 T6464 T6463 prep of,levels
R4404 T6465 T6466 amod cleaved,caspase-3
R4405 T6466 T6464 pobj caspase-3,of
R4406 T6467 T6466 cc and,caspase-3
R4407 T6468 T6466 conj Bax,caspase-3
R4408 T6469 T6470 auxpass were,found
R4409 T6470 T6460 ccomp found,showed
R441 T836 T835 prep of,Upregulation
R4410 T6471 T6472 advmod more,frequently
R4411 T6472 T6470 advmod frequently,found
R4412 T6473 T6470 prep in,found
R4413 T6474 T6476 det the,−
R4414 T6475 T6476 compound CCR5,−
R4415 T6476 T6473 pobj −,in
R4416 T6477 T6470 advmod /,found
R4417 T6478 T6479 nummod −,mice
R4418 T6479 T6477 dobj mice,/
R4419 T6480 T6479 prep than,mice
R442 T837 T836 pobj IL-1Ra,of
R4420 T6481 T6480 prep in,than
R4421 T6482 T6484 det the,+
R4422 T6483 T6484 compound CCR5,+
R4423 T6484 T6481 pobj +,in
R4424 T6485 T6487 amod /,mice
R4425 T6486 T6487 nummod +,mice
R4426 T6487 T6479 conj mice,mice
R4427 T6488 T6490 punct (,3B
R4428 T6489 T6490 compound Figure,3B
R4429 T6490 T6479 appos 3B,mice
R443 T838 T833 prep in,B
R4430 T6491 T6490 cc and,3B
R4431 T6492 T6490 conj 3C,3B
R4432 T6493 T6490 punct ),3B
R4433 T6494 T6460 punct .,showed
R4434 T6495 T6507 nsubj Consistent,showed
R4435 T6496 T6495 prep with,Consistent
R4436 T6497 T6499 det the,data
R4437 T6498 T6499 amod immunohistochemical,data
R4438 T6499 T6496 pobj data,with
R4439 T6500 T6499 punct ",",data
R444 T839 T838 pobj Melanoma,in
R4440 T6501 T6503 amod Western,analysis
R4441 T6502 T6503 compound blot,analysis
R4442 T6503 T6499 appos analysis,data
R4443 T6504 T6503 prep of,analysis
R4444 T6505 T6506 compound tumor,proteins
R4445 T6506 T6504 pobj proteins,of
R4446 T6507 T6507 ROOT showed,showed
R4447 T6508 T6510 amod greater,levels
R4448 T6509 T6510 amod increased,levels
R4449 T6510 T6507 dobj levels,showed
R445 T840 T842 nsubj Model,evaluate
R4450 T6511 T6510 prep of,levels
R4451 T6512 T6516 amod cleaved,caspase-9
R4452 T6513 T6516 amod caspase-3,caspase-9
R4453 T6514 T6516 punct ",",caspase-9
R4454 T6515 T6516 compound cleaved,caspase-9
R4455 T6516 T6511 pobj caspase-9,of
R4456 T6517 T6516 punct ",",caspase-9
R4457 T6518 T6519 compound cleaved,PARP
R4458 T6519 T6516 appos PARP,caspase-9
R4459 T6520 T6519 cc and,PARP
R446 T841 T842 aux To,evaluate
R4460 T6521 T6519 conj Bax,PARP
R4461 T6522 T6507 punct ",",showed
R4462 T6523 T6532 mark whereas,decreased
R4463 T6524 T6525 det the,levels
R4464 T6525 T6532 nsubjpass levels,decreased
R4465 T6526 T6525 prep of,levels
R4466 T6527 T6526 pobj Bcl-2,of
R4467 T6528 T6527 cc and,Bcl-2
R4468 T6529 T6527 conj C-IAP1,Bcl-2
R4469 T6530 T6532 auxpass were,decreased
R447 T842 T833 advcl evaluate,B
R4470 T6531 T6532 advmod significantly,decreased
R4471 T6532 T6507 advcl decreased,showed
R4472 T6533 T6532 prep in,decreased
R4473 T6534 T6539 nummod CCR5,tissues
R4474 T6535 T6538 nummod −,mice
R4475 T6536 T6538 nmod /,mice
R4476 T6537 T6538 nsubj −,mice
R4477 T6538 T6539 compound mice,tissues
R4478 T6539 T6533 pobj tissues,in
R4479 T6540 T6541 punct (,Figure
R448 T843 T844 det the,relevance
R4480 T6541 T6539 appos Figure,tissues
R4481 T6542 T6541 nummod 3D,Figure
R4482 T6543 T6541 punct ),Figure
R4483 T6544 T6507 punct .,showed
R449 T844 T842 dobj relevance,evaluate
R450 T845 T844 prep of,relevance
R451 T846 T849 compound C-C,type
R452 T847 T848 compound chemokine,receptor
R453 T848 T849 compound receptor,type
R454 T849 T845 pobj type,of
R455 T850 T849 nummod 5,type
R456 T851 T852 punct (,CCR5
R457 T852 T849 appos CCR5,type
R458 T853 T852 punct ),CCR5
R459 T854 T852 conj expression,CCR5
R460 T855 T854 cc and,expression
R461 T856 T857 compound tumor,development
R462 T857 T854 conj development,expression
R463 T858 T860 punct ",",compared
R464 T859 T860 nsubj we,compared
R465 T860 T860 ROOT compared,compared
R466 T861 T862 compound melanoma,growth
R467 T862 T860 dobj growth,compared
R4672 T6876 T6887 nsubj Upregulation,/
R4673 T6877 T6876 prep of,Upregulation
R4674 T6878 T6877 pobj IL-1Ra,of
R4675 T6879 T6876 prep in,Upregulation
R4676 T6880 T6881 det the,Tumor
R4677 T6881 T6879 pobj Tumor,in
R4678 T6882 T6881 cc and,Tumor
R4679 T6883 T6881 conj Spleen,Tumor
R468 T863 T862 prep in,growth
R4680 T6884 T6883 prep of,Spleen
R4681 T6885 T6886 compound CCR5,−
R4682 T6886 T6884 pobj −,of
R4683 T6887 T6887 ROOT /,/
R4684 T6888 T6889 nummod −,Mice
R4685 T6889 T6887 dobj Mice,/
R4686 T6890 T6891 aux To,investigate
R4687 T6891 T6887 advcl investigate,/
R4688 T6892 T6893 det the,difference
R4689 T6893 T6891 dobj difference,investigate
R469 T864 T865 nummod CCR5,knockout
R4690 T6894 T6893 prep in,difference
R4691 T6895 T6897 det the,levels
R4692 T6896 T6897 compound cytokine,levels
R4693 T6897 T6894 pobj levels,in
R4694 T6898 T6897 prep between,levels
R4695 T6899 T6900 det the,tumor
R4696 T6900 T6903 nmod tumor,tissues
R4697 T6901 T6900 cc and,tumor
R4698 T6902 T6900 conj spleen,tumor
R4699 T6903 T6898 pobj tissues,between
R470 T865 T863 pobj knockout,in
R4700 T6904 T6903 prep of,tissues
R4701 T6905 T6907 det the,+
R4702 T6906 T6907 compound CCR5,+
R4703 T6907 T6904 pobj +,of
R4704 T6908 T6887 conj /,/
R4705 T6909 T6908 dobj +,/
R4706 T6910 T6909 cc and,+
R4707 T6911 T6915 nummod CCR5,mice
R4708 T6912 T6915 nummod −,mice
R4709 T6913 T6915 nmod /,mice
R471 T866 T865 punct (,knockout
R4710 T6914 T6915 compound −,mice
R4711 T6915 T6908 dobj mice,/
R4712 T6916 T6918 punct ",",conducted
R4713 T6917 T6918 nsubj we,conducted
R4714 T6918 T6918 ROOT conducted,conducted
R4715 T6919 T6922 det a,assay
R4716 T6920 T6921 amod cytokine,array
R4717 T6921 T6922 compound array,assay
R4718 T6922 T6918 dobj assay,conducted
R4719 T6923 T6918 advcl using,conducted
R472 T867 T868 nummod CCR5,−
R4720 T6924 T6927 det a,Array
R4721 T6925 T6927 compound Mouse,Array
R4722 T6926 T6927 compound Proteome,Array
R4723 T6927 T6923 dobj Array,using
R4724 T6928 T6930 punct (,4A
R4725 T6929 T6930 compound Figure,4A
R4726 T6930 T6927 appos 4A,Array
R4727 T6931 T6930 punct ),4A
R4728 T6932 T6918 punct .,conducted
R4729 T6933 T6946 prep Among,increased
R473 T868 T870 nummod −,−
R4730 T6934 T6936 nummod 40,cytokines
R4731 T6935 T6936 amod tested,cytokines
R4732 T6936 T6933 pobj cytokines,Among
R4733 T6937 T6946 punct ",",increased
R4734 T6938 T6939 det the,levels
R4735 T6939 T6946 nsubj levels,increased
R4736 T6940 T6939 prep of,levels
R4737 T6941 T6940 pobj IL-1Ra,of
R4738 T6942 T6941 punct ",",IL-1Ra
R4739 T6943 T6941 conj MIG,IL-1Ra
R474 T869 T870 compound /,−
R4740 T6944 T6946 punct ",",increased
R4741 T6945 T6946 nsubj MIP-1α,increased
R4742 T6946 T6946 ROOT increased,increased
R4743 T6947 T6948 advmod about,686
R4744 T6948 T6946 npadvmod 686,increased
R4745 T6949 T6948 punct ",",686
R4746 T6950 T6948 conj 9,686
R4747 T6951 T6950 cc and,9
R4748 T6952 T6950 conj 25-fold,9
R4749 T6953 T6946 advmod respectively,increased
R475 T870 T865 appos −,knockout
R4750 T6954 T6946 punct ",",increased
R4751 T6955 T6946 prep in,increased
R4752 T6956 T6960 nummod CCR5,mice
R4753 T6957 T6960 nummod −,mice
R4754 T6958 T6960 compound /,mice
R4755 T6959 T6960 compound −,mice
R4756 T6960 T6955 pobj mice,in
R4757 T6961 T6946 prep compared,increased
R4758 T6962 T6961 prep to,compared
R4759 T6963 T6989 nummod CCR5,mice
R476 T871 T865 punct ),knockout
R4766 T6986 T6989 nummod +,mice
R4767 T6987 T6989 compound /,mice
R4768 T6988 T6989 compound +,mice
R4769 T6989 T6962 pobj mice,to
R477 T872 T863 pobj mice,in
R4770 T6990 T6946 punct .,increased
R4771 T6991 T6999 advcl Using,found
R4772 T6992 T6993 det this,technique
R4773 T6993 T6991 dobj technique,Using
R4774 T6994 T6999 punct ",",found
R4775 T6995 T6997 det no,cytokines
R4776 T6996 T6997 amod other,cytokines
R4777 T6997 T6999 nsubjpass cytokines,found
R4778 T6998 T6999 auxpass were,found
R4779 T6999 T6999 ROOT found,found
R478 T873 T872 cc and,mice
R4780 T7000 T7001 aux to,be
R4781 T7001 T6999 xcomp be,found
R4782 T7002 T7001 acomp different,be
R4783 T7003 T7002 prep between,different
R4784 T7004 T7006 det the,−
R4785 T7005 T7006 compound CCR5,−
R4786 T7006 T7003 pobj −,between
R4787 T7007 T6999 advcl /,found
R4788 T7008 T7009 nummod −,mice
R4789 T7009 T7007 dobj mice,/
R479 T874 T875 amod wild,type
R4790 T7010 T7009 cc and,mice
R4791 T7011 T7013 det the,+
R4792 T7012 T7013 compound CCR5,+
R4793 T7013 T7014 nsubj +,/
R4794 T7014 T7007 conj /,/
R4795 T7015 T7016 nummod +,mice
R4796 T7016 T7014 dobj mice,/
R4797 T7017 T7019 punct (,4B
R4798 T7018 T7019 compound Figure,4B
R4799 T7019 T7016 appos 4B,mice
R480 T875 T872 conj type,mice
R4800 T7020 T7016 punct ),mice
R4801 T7021 T7014 punct .,/
R4802 T7022 T7025 amod Similar,levels
R4803 T7023 T7025 amod altered,levels
R4804 T7024 T7025 compound cytokine,levels
R4805 T7025 T7027 nsubjpass levels,found
R4806 T7026 T7027 auxpass were,found
R4807 T7027 T7027 ROOT found,found
R4808 T7028 T7027 prep in,found
R4809 T7029 T7030 det the,spleens
R481 T876 T880 punct (,+
R4810 T7030 T7028 pobj spleens,in
R4811 T7031 T7030 prep of,spleens
R4812 T7032 T7036 nummod CCR5,mice
R4813 T7033 T7036 nummod −,mice
R4814 T7034 T7036 nmod /,mice
R4815 T7035 T7036 compound −,mice
R4816 T7036 T7031 pobj mice,of
R4817 T7037 T7039 punct (,4C
R4818 T7038 T7039 compound Figure,4C
R4819 T7039 T7036 appos 4C,mice
R482 T877 T880 nummod CCR5,+
R4820 T7040 T7027 punct ),found
R4821 T7041 T7027 punct .,found
R4822 T7042 T7046 mark Since,was
R4823 T7043 T7045 det the,level
R4824 T7044 T7045 amod IL-1Ra,level
R4825 T7045 T7046 nsubj level,was
R4826 T7046 T7062 advcl was,analyzed
R4827 T7047 T7050 det the,elevated
R4828 T7048 T7050 advmod most,elevated
R4829 T7049 T7050 advmod significantly,elevated
R483 T878 T880 nummod +,+
R4830 T7050 T7046 attr elevated,was
R4831 T7051 T7050 punct ",",elevated
R4832 T7052 T7053 det the,expression
R4833 T7053 T7062 nsubjpass expression,analyzed
R4834 T7054 T7053 prep of,expression
R4835 T7055 T7054 pobj IL-1Ra,of
R4836 T7056 T7053 prep in,expression
R4837 T7057 T7060 nmod tumor,tissues
R4838 T7058 T7057 cc and,tumor
R4839 T7059 T7057 conj spleen,tumor
R484 T879 T880 compound /,+
R4840 T7060 T7056 pobj tissues,in
R4841 T7061 T7062 auxpass was,analyzed
R4842 T7062 T7062 ROOT analyzed,analyzed
R4843 T7063 T7062 agent by,analyzed
R4844 T7064 T7063 pobj immunofluorescence,by
R4845 T7065 T7064 cc and,immunofluorescence
R4846 T7066 T7064 conj western,immunofluorescence
R4847 T7067 T7064 conj blotting,immunofluorescence
R4848 T7068 T7062 punct .,analyzed
R4849 T7069 T7070 det The,expression
R485 T880 T875 appos +,type
R4850 T7070 T7074 nsubjpass expression,upregulated
R4851 T7071 T7070 prep of,expression
R4852 T7072 T7071 pobj IL-1Ra,of
R4853 T7073 T7074 auxpass was,upregulated
R4854 T7074 T7074 ROOT upregulated,upregulated
R4855 T7075 T7074 prep in,upregulated
R4856 T7076 T7075 pobj tumor,in
R4857 T7077 T7076 cc and,tumor
R4858 T7078 T7076 conj spleen,tumor
R4859 T7079 T7084 nsubj tissues,/
R486 T881 T880 punct ),+
R4860 T7080 T7079 prep of,tissues
R4861 T7081 T7083 det the,−
R4862 T7082 T7083 compound CCR5,−
R4863 T7083 T7080 pobj −,of
R4864 T7084 T7084 ROOT /,/
R4865 T7085 T7086 nummod −,mice
R4866 T7086 T7084 dobj mice,/
R4867 T7087 T7089 punct (,4D-G
R4868 T7088 T7089 compound Figure,4D-G
R4869 T7089 T7086 appos 4D-G,mice
R487 T882 T875 conj mice,type
R4870 T7090 T7086 punct ),mice
R4871 T7091 T7084 punct .,/
R488 T883 T860 punct .,compared
R489 T884 T888 nummod CCR5,mice
R490 T885 T888 nummod −,mice
R491 T886 T888 compound /,mice
R492 T887 T888 compound −,mice
R493 T888 T889 nsubj mice,showed
R494 T889 T889 ROOT showed,showed
R495 T890 T892 amod reduced,volume
R496 T891 T892 compound tumor,volume
R497 T892 T889 dobj volume,showed
R498 T893 T892 punct ",",volume
R499 T894 T895 compound tumor,weight
R500 T895 T892 conj weight,volume
R501 T896 T889 punct ",",showed
R502 T897 T889 cc and,showed
R503 T898 T900 amod increased,rate
R504 T899 T900 compound survival,rate
R505 T900 T902 dobj rate,compared
R506 T901 T902 advmod when,compared
R507 T902 T889 conj compared,showed
R508 T903 T902 prep to,compared
R509 T904 T908 nummod CCR5,mice
R510 T905 T908 nummod +,mice
R511 T906 T908 compound /,mice
R512 T907 T908 compound +,mice
R513 T908 T903 pobj mice,to
R514 T909 T889 punct .,showed
R515 T910 T911 nsubj We,investigated
R516 T911 T911 ROOT investigated,investigated
R517 T912 T913 det the,activation
R518 T913 T911 dobj activation,investigated
R519 T914 T913 prep of,activation
R520 T915 T914 pobj NF-κB,of
R521 T916 T918 mark since,is
R522 T917 T918 nsubj it,is
R523 T918 T911 advcl is,investigated
R524 T919 T922 det an,factor
R525 T920 T922 amod implicated,factor
R526 T921 T922 compound transcription,factor
R527 T922 T918 attr factor,is
R528 T923 T922 prep in,factor
R529 T924 T925 det the,regulation
R530 T925 T923 pobj regulation,in
R531 T926 T925 prep of,regulation
R532 T927 T926 pobj genes,of
R533 T928 T927 acl involving,genes
R534 T929 T930 compound cell,growth
R535 T930 T928 dobj growth,involving
R536 T931 T930 punct ",",growth
R5367 T8102 T8143 nsubj Induction,analyzed
R5368 T8103 T8102 prep of,Induction
R5369 T8104 T8105 compound CD8,T
R537 T932 T930 conj apoptosis,growth
R5370 T8105 T8106 compound T,cells
R5371 T8106 T8103 pobj cells,of
R5372 T8107 T8106 cc and,cells
R5373 T8108 T8110 compound NK,Infiltration
R5374 T8109 T8110 compound Cell,Infiltration
R5375 T8110 T8106 conj Infiltration,cells
R5376 T8111 T8110 prep into,Infiltration
R5377 T8112 T8111 pobj Tumor,into
R5378 T8113 T8112 cc and,Tumor
R5379 T8114 T8112 conj Spleen,Tumor
R538 T933 T932 punct ",",apoptosis
R5380 T8115 T8114 prep of,Spleen
R5381 T8116 T8117 compound CCR5,−
R5382 T8117 T8115 pobj −,of
R5383 T8118 T8143 advcl /,analyzed
R5384 T8119 T8120 nummod −,Mice
R5385 T8120 T8118 npadvmod Mice,/
R5386 T8121 T8122 aux To,investigate
R5387 T8122 T8118 advcl investigate,/
R5388 T8123 T8136 mark whether,related
R5389 T8124 T8125 det the,inhibition
R539 T934 T932 cc and,apoptosis
R5390 T8125 T8136 nsubjpass inhibition,related
R5391 T8126 T8125 prep of,inhibition
R5392 T8127 T8128 compound tumor,growth
R5393 T8128 T8126 pobj growth,of
R5394 T8129 T8125 prep in,inhibition
R5395 T8130 T8134 nummod CCR5,mice
R5396 T8131 T8134 nummod −,mice
R5397 T8132 T8134 nmod /,mice
R5398 T8133 T8134 compound −,mice
R5399 T8134 T8129 pobj mice,in
R540 T935 T936 compound tumor,growth
R5400 T8135 T8136 auxpass is,related
R5401 T8136 T8122 ccomp related,investigate
R5402 T8137 T8136 prep to,related
R5403 T8138 T8140 amod tumor-specific,responses
R5404 T8139 T8140 amod immune,responses
R5405 T8140 T8137 pobj responses,to
R5406 T8141 T8143 punct ",",analyzed
R5407 T8142 T8143 nsubj we,analyzed
R5408 T8143 T8143 ROOT analyzed,analyzed
R5409 T8144 T8146 det the,patterns
R541 T936 T932 conj growth,apoptosis
R5410 T8145 T8146 compound distribution,patterns
R5411 T8146 T8143 dobj patterns,analyzed
R5412 T8147 T8146 prep of,patterns
R5413 T8148 T8152 nummod CD8,cell
R5414 T8149 T8152 nummod +,cell
R5415 T8150 T8152 amod cytotoxic,cell
R5416 T8151 T8152 compound T,cell
R5417 T8152 T8147 pobj cell,of
R5418 T8153 T8152 cc and,cell
R5419 T8154 T8157 compound CD57,Killer
R542 T937 T911 punct .,investigated
R5420 T8155 T8157 compound +,Killer
R5421 T8156 T8157 compound Natural,Killer
R5422 T8157 T8158 compound Killer,cells
R5423 T8158 T8152 conj cells,cell
R5424 T8159 T8146 prep in,patterns
R5425 T8160 T8163 nmod tumor,tissues
R5426 T8161 T8160 cc and,tumor
R5427 T8162 T8160 conj spleen,tumor
R5428 T8163 T8159 pobj tissues,in
R5429 T8164 T8143 punct .,analyzed
R543 T938 T939 amod Significant,inhibition
R5430 T8165 T8178 prep By,found
R5431 T8166 T8165 pcomp staining,By
R5432 T8167 T8169 det the,sections
R5433 T8168 T8169 compound tumor,sections
R5434 T8169 T8166 dobj sections,staining
R5435 T8170 T8166 prep from,staining
R5436 T8171 T8172 nummod CCR5,−
R5437 T8172 T8175 nummod −,mice
R5438 T8173 T8175 nmod /,mice
R5439 T8174 T8175 compound −,mice
R544 T939 T964 nsubjpass inhibition,found
R5440 T8175 T8170 pobj mice,from
R5441 T8176 T8178 punct ",",found
R5442 T8177 T8178 nsubj we,found
R5443 T8178 T8178 ROOT found,found
R5444 T8179 T8181 mark that,was
R5445 T8180 T8181 expl there,was
R5446 T8181 T8178 ccomp was,found
R5447 T8182 T8184 det a,influx
R5448 T8183 T8184 amod significant,influx
R5449 T8184 T8181 attr influx,was
R545 T940 T939 prep of,inhibition
R5450 T8185 T8184 prep of,influx
R5451 T8186 T8188 nummod CD8,cells
R5452 T8187 T8188 nummod +,cells
R5453 T8188 T8185 pobj cells,of
R5454 T8189 T8184 prep into,influx
R5455 T8190 T8191 det the,tumor
R5456 T8191 T8189 pobj tumor,into
R5457 T8192 T8184 punct ",",influx
R5458 T8193 T8195 advmod as,as
R5459 T8194 T8195 advmod well,as
R546 T941 T940 pobj DNA,of
R5460 T8195 T8184 cc as,influx
R5461 T8196 T8197 det an,increase
R5462 T8197 T8184 conj increase,influx
R5463 T8198 T8197 prep in,increase
R5464 T8199 T8200 det the,number
R5465 T8200 T8198 pobj number,in
R5466 T8201 T8200 prep of,number
R5467 T8202 T8201 pcomp infiltrating,of
R5468 T8203 T8204 compound NK,cells
R5469 T8204 T8202 dobj cells,infiltrating
R547 T942 T943 amod binding,activity
R5470 T8205 T8207 punct (,5A
R5471 T8206 T8207 compound Figure,5A
R5472 T8207 T8204 appos 5A,cells
R5473 T8208 T8204 punct ),cells
R5474 T8209 T8178 punct .,found
R5475 T8210 T8213 nummod CD8,cells
R5476 T8211 T8213 nummod +,cells
R5477 T8212 T8213 compound T,cells
R5478 T8213 T8220 nsubjpass cells,spread
R5479 T8214 T8213 cc and,cells
R548 T943 T939 conj activity,inhibition
R5480 T8215 T8213 conj CD57,cells
R5481 T8216 T8218 compound +,cells
R5482 T8217 T8218 compound NK,cells
R5483 T8218 T8213 conj cells,cells
R5484 T8219 T8220 auxpass were,spread
R5485 T8220 T8220 ROOT spread,spread
R5486 T8221 T8220 advmod diffusely,spread
R5487 T8222 T8220 prep throughout,spread
R5488 T8223 T8225 det the,sections
R5489 T8224 T8225 amod entire,sections
R549 T944 T943 prep of,activity
R5490 T8225 T8222 pobj sections,throughout
R5491 T8226 T8220 punct .,spread
R5492 T8227 T8229 aux To,investigate
R5493 T8228 T8229 advmod further,investigate
R5494 T8229 T8263 advcl investigate,analyzed
R5495 T8230 T8231 det the,differences
R5496 T8231 T8229 dobj differences,investigate
R5497 T8232 T8231 prep in,differences
R5498 T8233 T8234 det the,numbers
R5499 T8234 T8232 pobj numbers,in
R550 T945 T944 pobj NF-κB,of
R5500 T8235 T8234 prep of,numbers
R5501 T8236 T8239 nummod CD8,cells
R5502 T8237 T8239 nummod +,cells
R5503 T8238 T8239 compound T,cells
R5504 T8239 T8235 pobj cells,of
R5505 T8240 T8239 cc and,cells
R5506 T8241 T8243 compound CD57,NK
R5507 T8242 T8243 compound +,NK
R5508 T8243 T8244 compound NK,cells
R5509 T8244 T8239 conj cells,cells
R551 T946 T943 punct ",",activity
R5510 T8245 T8231 prep between,differences
R5511 T8246 T8250 nummod CCR5,mice
R5512 T8247 T8250 nummod +,mice
R5513 T8248 T8250 compound /,mice
R5514 T8249 T8250 compound +,mice
R5515 T8250 T8245 pobj mice,between
R5516 T8251 T8250 cc and,mice
R5517 T8252 T8250 conj CCR5,mice
R5518 T8253 T8263 prep −,analyzed
R5519 T8254 T8256 nummod /,mice
R552 T947 T943 cc and,activity
R5520 T8255 T8256 nummod −,mice
R5521 T8256 T8253 dobj mice,−
R5522 T8257 T8253 prep in,−
R5523 T8258 T8259 amod immunity-related,organ
R5524 T8259 T8257 pobj organ,in
R5525 T8260 T8263 punct ",",analyzed
R5526 T8261 T8263 nsubj we,analyzed
R5527 T8262 T8263 advmod also,analyzed
R5528 T8263 T8263 ROOT analyzed,analyzed
R5529 T8264 T8265 det the,CD8
R553 T948 T943 conj translocation,activity
R5530 T8265 T8270 nmod CD8,number
R5531 T8266 T8265 cc and,CD8
R5532 T8267 T8265 conj CD57,CD8
R5533 T8268 T8270 amod reactive,number
R5534 T8269 T8270 compound cell,number
R5535 T8270 T8263 dobj number,analyzed
R5536 T8271 T8270 prep in,number
R5537 T8272 T8273 compound spleen,tissues
R5538 T8273 T8271 pobj tissues,in
R5539 T8274 T8263 punct .,analyzed
R554 T949 T948 prep of,translocation
R5540 T8275 T8276 det The,number
R5541 T8276 T8287 nsubj number,were
R5542 T8277 T8276 prep of,number
R5543 T8278 T8281 nummod CD8,cells
R5544 T8279 T8281 nummod +,cells
R5545 T8280 T8281 compound T,cells
R5546 T8281 T8277 pobj cells,of
R5547 T8282 T8281 cc and,cells
R5548 T8283 T8285 compound CD57,NK
R5549 T8284 T8285 compound +,NK
R555 T950 T949 pobj p50,of
R5550 T8285 T8286 compound NK,cells
R5551 T8286 T8281 conj cells,cells
R5552 T8287 T8287 ROOT were,were
R5553 T8288 T8287 acomp higher,were
R5554 T8289 T8288 prep in,higher
R5555 T8290 T8291 det the,spleen
R5556 T8291 T8289 pobj spleen,in
R5557 T8292 T8291 prep of,spleen
R5558 T8293 T8295 det the,−
R5559 T8294 T8295 compound CCR5,−
R556 T951 T950 cc and,p50
R5560 T8295 T8292 pobj −,of
R5561 T8296 T8287 conj /,were
R5562 T8297 T8298 nummod −,mice
R5563 T8298 T8296 dobj mice,/
R5564 T8299 T8298 prep than,mice
R5565 T8300 T8299 prep in,than
R5566 T8301 T8302 det the,spleen
R5567 T8302 T8300 pobj spleen,in
R5568 T8303 T8302 prep of,spleen
R5569 T8304 T8306 det the,+
R557 T952 T950 conj p65,p50
R5570 T8305 T8306 compound CCR5,+
R5571 T8306 T8303 pobj +,of
R5572 T8307 T8309 amod /,mice
R5573 T8308 T8309 nummod +,mice
R5574 T8309 T8298 conj mice,mice
R5575 T8310 T8312 punct (,5B
R5576 T8311 T8312 compound Figure,5B
R5577 T8312 T8309 appos 5B,mice
R5578 T8313 T8309 punct ),mice
R5579 T8314 T8287 punct .,were
R558 T953 T939 prep into,inhibition
R5580 T8315 T8316 det These,data
R5581 T8316 T8317 nsubj data,suggest
R5582 T8317 T8317 ROOT suggest,suggest
R5583 T8318 T8340 mark that,play
R5584 T8319 T8340 prep by,play
R5585 T8320 T8319 pcomp promoting,by
R5586 T8321 T8322 det the,infiltration
R5587 T8322 T8320 dobj infiltration,promoting
R5588 T8323 T8322 prep of,infiltration
R5589 T8324 T8326 nummod CD8,cells
R559 T954 T955 det the,nucleus
R5590 T8325 T8326 compound T,cells
R5591 T8326 T8323 pobj cells,of
R5592 T8327 T8326 cc and,cells
R5593 T8328 T8329 compound NK,cells
R5594 T8329 T8326 conj cells,cells
R5595 T8330 T8326 punct ",",cells
R5596 T8331 T8332 nsubj which,are
R5597 T8332 T8319 relcl are,by
R5598 T8333 T8335 amod potent,effectors
R5599 T8334 T8335 amod cytotoxic,effectors
R560 T955 T953 pobj nucleus,into
R5600 T8335 T8332 attr effectors,are
R5601 T8336 T8335 prep for,effectors
R5602 T8337 T8336 pobj tumors,for
R5603 T8338 T8340 punct ",",play
R5604 T8339 T8340 aux could,play
R5605 T8340 T8317 ccomp play,suggest
R5606 T8341 T8342 det a,role
R5607 T8342 T8340 dobj role,play
R5608 T8343 T8340 prep in,play
R5609 T8344 T8346 det an,effect
R561 T956 T939 prep through,inhibition
R5610 T8345 T8346 amod anti-tumor,effect
R5611 T8346 T8343 pobj effect,in
R5612 T8347 T8340 prep in,play
R5613 T8348 T8352 nummod CCR5,mice
R5614 T8349 T8352 nummod −,mice
R5615 T8350 T8352 nmod /,mice
R5616 T8351 T8352 amod −,mice
R5617 T8352 T8347 pobj mice,in
R5618 T8353 T8317 punct .,suggest
R5619 T8354 T8355 aux To,analyze
R562 T957 T958 det the,inhibition
R5620 T8355 T8380 advcl analyze,were
R5621 T8356 T8359 det the,change
R5622 T8357 T8358 compound cell,phenotype
R5623 T8358 T8359 compound phenotype,change
R5624 T8359 T8355 dobj change,analyze
R5625 T8360 T8359 prep in,change
R5626 T8361 T8365 nummod CCR5,mice
R5627 T8362 T8365 nummod −,mice
R5628 T8363 T8365 nmod /,mice
R5629 T8364 T8365 compound −,mice
R563 T958 T956 pobj inhibition,through
R5630 T8365 T8360 pobj mice,in
R5631 T8366 T8365 cc and,mice
R5632 T8367 T8365 conj CCR5,mice
R5633 T8368 T8380 advcl +,were
R5634 T8369 T8371 nummod /,mice
R5635 T8370 T8371 nummod +,mice
R5636 T8371 T8368 dobj mice,+
R5637 T8372 T8368 prep by,+
R5638 T8373 T8372 pobj inoculation,by
R5639 T8374 T8373 prep of,inoculation
R564 T959 T958 prep of,inhibition
R5640 T8375 T8377 det the,cell
R5641 T8376 T8377 compound melanoma,cell
R5642 T8377 T8374 pobj cell,of
R5643 T8378 T8380 punct ",",were
R5644 T8379 T8380 nsubj lymphocytes,were
R5645 T8380 T8380 ROOT were,were
R5646 T8381 T8380 acomp isolated,were
R5647 T8382 T8381 prep from,isolated
R5648 T8383 T8384 det the,tumor
R5649 T8384 T8387 nmod tumor,tissues
R565 T960 T959 pobj phosphorylation,of
R5650 T8385 T8384 cc and,tumor
R5651 T8386 T8384 conj spleen,tumor
R5652 T8387 T8382 pobj tissues,from
R5653 T8388 T8380 punct .,were
R5654 T8389 T8390 compound The,B
R5655 T8390 T8413 nsubj B,were
R5656 T8391 T8390 punct ",",B
R5657 T8392 T8393 compound CD3,T
R5658 T8393 T8390 appos T,B
R5659 T8394 T8393 punct ",",T
R566 T961 T960 prep of,phosphorylation
R5660 T8395 T8396 compound CD4,T
R5661 T8396 T8390 appos T,B
R5662 T8397 T8396 punct ",",T
R5663 T8398 T8396 appos CD,T
R5664 T8399 T8400 nummod 8,T
R5665 T8400 T8390 appos T,B
R5666 T8401 T8400 cc and,T
R5667 T8402 T8404 compound NK,portion
R5668 T8403 T8404 compound cell,portion
R5669 T8404 T8400 conj portion,T
R567 T962 T961 pobj IκB,of
R5670 T8405 T8404 prep of,portion
R5671 T8406 T8410 nummod CCR5,mice
R5672 T8407 T8410 nummod −,mice
R5673 T8408 T8410 nmod /,mice
R5674 T8409 T8410 nsubj −,mice
R5675 T8410 T8405 pobj mice,of
R5676 T8411 T8412 compound tumor,tissue
R5677 T8412 T8404 conj tissue,portion
R5678 T8413 T8413 ROOT were,were
R5679 T8414 T8415 nummod 7.2,%
R568 T963 T964 auxpass was,found
R5680 T8415 T8413 attr %,were
R5681 T8416 T8415 punct ",",%
R5682 T8417 T8418 nummod 48.2,%
R5683 T8418 T8415 appos %,%
R5684 T8419 T8418 punct ",",%
R5685 T8420 T8421 nummod 16.9,%
R5686 T8421 T8418 conj %,%
R5687 T8422 T8421 punct ",",%
R5688 T8423 T8424 nummod 32.1,%
R5689 T8424 T8421 conj %,%
R569 T964 T964 ROOT found,found
R5690 T8425 T8424 cc and,%
R5691 T8426 T8427 nummod 7.8,%
R5692 T8427 T8424 conj %,%
R5693 T8428 T8427 punct ",",%
R5694 T8429 T8427 advmod respectively,%
R5695 T8430 T8413 punct ",",were
R5696 T8431 T8413 prep compared,were
R5697 T8432 T8431 prep to,compared
R5698 T8433 T8434 nummod 2.9,%
R5699 T8434 T8432 pobj %,to
R570 T965 T964 prep in,found
R5700 T8435 T8434 punct ",",%
R5701 T8436 T8437 nummod 11.1,%
R5702 T8437 T8434 appos %,%
R5703 T8438 T8437 punct ",",%
R5704 T8439 T8440 nummod 2.3,%
R5705 T8440 T8437 conj %,%
R5706 T8441 T8440 punct ",",%
R5707 T8442 T8443 nummod 0.6,%
R5708 T8443 T8440 conj %,%
R5709 T8444 T8443 cc and,%
R571 T966 T968 det the,tissues
R5710 T8445 T8446 nummod 3.1,%
R5711 T8446 T8443 conj %,%
R5712 T8447 T8446 prep of,%
R5713 T8448 T8452 nummod CCR5,mice
R5714 T8449 T8452 nummod +,mice
R5715 T8450 T8452 compound /,mice
R5716 T8451 T8452 compound +,mice
R5717 T8452 T8447 pobj mice,of
R5718 T8453 T8455 punct (,5C
R5719 T8454 T8455 compound Figure,5C
R572 T967 T968 compound melanoma,tissues
R5720 T8455 T8452 appos 5C,mice
R5721 T8456 T8434 punct ),%
R5722 T8457 T8413 punct .,were
R5723 T8458 T8459 det The,lymphocytes
R5724 T8459 T8469 nsubj lymphocytes,/
R5725 T8460 T8461 nsubj that,infiltrated
R5726 T8461 T8459 relcl infiltrated,lymphocytes
R5727 T8462 T8464 det the,tissue
R5728 T8463 T8464 compound tumor,tissue
R5729 T8464 T8461 dobj tissue,infiltrated
R573 T968 T965 pobj tissues,in
R5730 T8465 T8464 prep of,tissue
R5731 T8466 T8468 det the,−
R5732 T8467 T8468 compound CCR5,−
R5733 T8468 T8465 pobj −,of
R5734 T8469 T8469 ROOT /,/
R5735 T8470 T8471 nummod −,mice
R5736 T8471 T8473 nsubj mice,had
R5737 T8472 T8473 advmod also,had
R5738 T8473 T8469 conj had,/
R5739 T8474 T8475 amod higher,levels
R574 T969 T968 prep of,tissues
R5740 T8475 T8473 dobj levels,had
R5741 T8476 T8475 prep of,levels
R5742 T8477 T8476 pobj CD19,of
R5743 T8478 T8477 punct ",",CD19
R5744 T8479 T8477 conj CD3,CD19
R5745 T8480 T8479 punct ",",CD3
R5746 T8481 T8479 conj CD4,CD3
R5747 T8482 T8481 punct ",",CD4
R5748 T8483 T8481 conj CD8,CD4
R5749 T8484 T8483 cc and,CD8
R575 T970 T974 nummod CCR5,mice
R5750 T8485 T8483 conj CD57,CD8
R5751 T8486 T8487 advmod when,compared
R5752 T8487 T8473 advcl compared,had
R5753 T8488 T8487 prep to,compared
R5754 T8489 T8491 det the,+
R5755 T8490 T8491 compound CCR5,+
R5756 T8491 T8492 compound +,/
R5757 T8492 T8488 pobj /,to
R5758 T8493 T8494 nummod +,mice
R5759 T8494 T8492 dobj mice,/
R576 T971 T974 nummod −,mice
R5760 T8495 T8473 punct .,had
R5761 T8496 T8497 det The,B
R5762 T8497 T8511 poss B,portion
R5763 T8498 T8497 punct ",",B
R5764 T8499 T8500 compound CD3,T
R5765 T8500 T8497 appos T,B
R5766 T8501 T8500 punct ",",T
R5767 T8502 T8503 compound CD4,T
R5768 T8503 T8497 appos T,B
R5769 T8504 T8503 punct ",",T
R577 T972 T974 compound /,mice
R5770 T8505 T8503 appos CD,T
R5771 T8506 T8507 nummod 8,T
R5772 T8507 T8497 conj T,B
R5773 T8508 T8507 cc and,T
R5774 T8509 T8507 conj NK,T
R5775 T8510 T8511 compound cell,portion
R5776 T8511 T8520 nsubj portion,were
R5777 T8512 T8511 prep of,portion
R5778 T8513 T8519 det the,spleen
R5779 T8514 T8519 compound CCR5,spleen
R578 T973 T974 compound −,mice
R5780 T8515 T8518 nummod −,mice
R5781 T8516 T8518 nummod /,mice
R5782 T8517 T8518 compound −,mice
R5783 T8518 T8519 compound mice,spleen
R5784 T8519 T8512 pobj spleen,of
R5785 T8520 T8520 ROOT were,were
R5786 T8521 T8522 nummod 61.3,%
R5787 T8522 T8520 attr %,were
R5788 T8523 T8522 punct ",",%
R5789 T8524 T8525 nummod 33.4,%
R579 T974 T969 pobj mice,of
R5790 T8525 T8522 appos %,%
R5791 T8526 T8525 punct ",",%
R5792 T8527 T8528 nummod 17.6,%
R5793 T8528 T8525 conj %,%
R5794 T8529 T8528 punct ",",%
R5795 T8530 T8531 nummod 9.2,%
R5796 T8531 T8528 conj %,%
R5797 T8532 T8531 cc and,%
R5798 T8533 T8534 nummod 0.6,%
R5799 T8534 T8531 conj %,%
R580 T975 T964 prep compared,found
R5800 T8535 T8522 punct ",",%
R5801 T8536 T8537 advmod respectively,compared
R5802 T8537 T8520 prep compared,were
R5803 T8538 T8537 prep to,compared
R5804 T8539 T8540 nummod 38.3,%
R5805 T8540 T8538 pobj %,to
R5806 T8541 T8540 punct ",",%
R5807 T8542 T8543 nummod 5.9,%
R5808 T8543 T8557 nsubj %,/
R5809 T8544 T8543 punct ",",%
R581 T976 T975 prep to,compared
R5810 T8545 T8546 nummod 4.0,%
R5811 T8546 T8543 conj %,%
R5812 T8547 T8546 punct ",",%
R5813 T8548 T8549 nummod 1.0,%
R5814 T8549 T8546 conj %,%
R5815 T8550 T8549 cc and,%
R5816 T8551 T8552 nummod 3.9,%
R5817 T8552 T8549 conj %,%
R5818 T8553 T8552 prep of,%
R5819 T8554 T8556 det the,+
R582 T977 T978 compound melanoma,tissues
R5820 T8555 T8556 compound CCR5,+
R5821 T8556 T8553 pobj +,of
R5822 T8557 T8520 conj /,were
R5823 T8558 T8559 nummod +,mice
R5824 T8559 T8557 dobj mice,/
R5825 T8560 T8561 punct (,Figure
R5826 T8561 T8559 appos Figure,mice
R5827 T8562 T8561 nummod 5D,Figure
R5828 T8563 T8561 punct ),Figure
R5829 T8564 T8557 punct .,/
R583 T978 T976 pobj tissues,to
R5830 T8565 T8566 det These,data
R5831 T8566 T8567 nsubj data,suggest
R5832 T8567 T8567 ROOT suggest,suggest
R5833 T8568 T8582 mark that,are
R5834 T8569 T8582 prep by,are
R5835 T8570 T8569 pcomp promoting,by
R5836 T8571 T8572 det the,infiltration
R5837 T8572 T8570 dobj infiltration,promoting
R5838 T8573 T8572 prep of,infiltration
R5839 T8574 T8576 nummod CD8,cells
R584 T979 T978 prep of,tissues
R5840 T8575 T8576 compound T,cells
R5841 T8576 T8573 pobj cells,of
R5842 T8577 T8576 cc and,cells
R5843 T8578 T8579 compound NK,cells
R5844 T8579 T8576 conj cells,cells
R5845 T8580 T8576 punct ",",cells
R5846 T8581 T8582 nsubj which,are
R5847 T8582 T8567 ccomp are,suggest
R5848 T8583 T8585 amod potent,effectors
R5849 T8584 T8585 amod cytotoxic,effectors
R585 T980 T984 nummod CCR5,mice
R5850 T8585 T8582 attr effectors,are
R5851 T8586 T8585 prep for,effectors
R5852 T8587 T8586 pobj tumors,for
R5853 T8588 T8590 punct ",",play
R5854 T8589 T8590 aux could,play
R5855 T8590 T8567 conj play,suggest
R5856 T8591 T8592 det a,role
R5857 T8592 T8590 dobj role,play
R5858 T8593 T8592 prep in,role
R5859 T8594 T8595 det the,inhibition
R586 T981 T984 nummod +,mice
R5860 T8595 T8593 pobj inhibition,in
R5861 T8596 T8595 prep of,inhibition
R5862 T8597 T8598 compound tumor,growth
R5863 T8598 T8596 pobj growth,of
R5864 T8599 T8590 prep in,play
R5865 T8600 T8604 nummod CCR5,mice
R5866 T8601 T8604 nummod −,mice
R5867 T8602 T8604 nmod /,mice
R5868 T8603 T8604 compound −,mice
R5869 T8604 T8599 pobj mice,in
R587 T982 T984 amod /,mice
R5870 T8605 T8567 punct .,suggest
R588 T983 T984 amod +,mice
R589 T984 T979 pobj mice,of
R590 T985 T964 punct .,found
R591 T986 T987 amod NF-κB,target
R592 T987 T1004 nsubjpass target,elevated
R593 T988 T990 amod apoptotic,expression
R594 T989 T990 compound protein,expression
R595 T990 T987 appos expression,target
R596 T991 T987 punct ",",target
R597 T992 T993 amod such,as
R598 T993 T987 prep as,target
R599 T994 T1004 nsubjpass cleaved,elevated
R600 T995 T1004 nsubjpass caspase-3,elevated
R601 T996 T998 punct ",",PARP
R602 T997 T998 compound cleaved,PARP
R603 T998 T995 appos PARP,caspase-3
R604 T999 T998 punct ",",PARP
R605 T1000 T998 cc and,PARP
R606 T1001 T998 conj Bax,PARP
R607 T1002 T1004 punct ",",elevated
R608 T1003 T1004 auxpass was,elevated
R609 T1004 T1004 ROOT elevated,elevated
R610 T1005 T1004 punct ",",elevated
R611 T1006 T1020 mark whereas,decreased
R612 T1007 T1011 det the,levels
R613 T1008 T1009 compound survival,protein
R614 T1009 T1011 compound protein,levels
R615 T1010 T1011 compound expression,levels
R616 T1011 T1020 nsubjpass levels,decreased
R617 T1012 T1011 punct ",",levels
R618 T1013 T1014 amod such,as
R619 T1014 T1011 prep as,levels
R620 T1015 T1014 pobj Bcl-2,as
R621 T1016 T1015 punct ",",Bcl-2
R622 T1017 T1015 conj C-IAP1,Bcl-2
R623 T1018 T1020 punct ",",decreased
R624 T1019 T1020 auxpass was,decreased
R625 T1020 T1004 advcl decreased,elevated
R626 T1021 T1020 prep in,decreased
R627 T1022 T1024 det the,tissues
R628 T1130 T1129 pobj NF-κB,of
R629 T1023 T1024 compound melanoma,tissues
R630 T1024 T1021 pobj tissues,in
R631 T1025 T1024 prep of,tissues
R632 T1026 T1030 nummod CCR5,mice
R633 T1027 T1030 nummod −,mice
R634 T1028 T1030 nmod /,mice
R635 T1029 T1030 compound −,mice
R636 T1030 T1025 pobj mice,of
R637 T1031 T1004 punct .,elevated
R638 T1032 T1035 advmod Interestingly,found
R639 T1033 T1035 punct ",",found
R640 T1034 T1035 nsubj we,found
R641 T1035 T1035 ROOT found,found
R642 T1036 T1050 mark that,elevated
R643 T1037 T1038 det the,level
R644 T1038 T1050 nsubjpass level,elevated
R645 T1039 T1038 prep of,level
R646 T1040 T1039 pobj IL-1Ra,of
R647 T1041 T1040 punct ",",IL-1Ra
R648 T1042 T1044 det a,growth
R649 T1043 T1044 compound tumor,growth
R650 T1044 T1040 appos growth,IL-1Ra
R651 T1045 T1046 amod suppressive,cytokine
R652 T1046 T1044 appos cytokine,growth
R653 T1047 T1050 punct ",",elevated
R654 T1048 T1050 auxpass was,elevated
R655 T1049 T1050 advmod significantly,elevated
R656 T1050 T1035 ccomp elevated,found
R657 T1051 T1050 prep in,elevated
R658 T1052 T1053 compound tumor,tissue
R659 T1053 T1051 pobj tissue,in
R660 T1054 T1053 cc and,tissue
R661 T1055 T1053 conj spleen,tissue
R662 T1056 T1055 prep of,spleen
R663 T1057 T1061 nummod CCR5,mice
R664 T1058 T1061 nummod −,mice
R665 T1059 T1061 compound /,mice
R666 T1060 T1061 compound −,mice
R667 T1061 T1056 pobj mice,of
R668 T1062 T1050 prep compared,elevated
R669 T1063 T1062 prep to,compared
R670 T1064 T1065 det the,level
R671 T1065 T1063 pobj level,to
R672 T1066 T1065 prep in,level
R673 T1067 T1071 nummod CCR5,mice
R674 T1068 T1071 nummod +,mice
R675 T1069 T1071 compound /,mice
R676 T1070 T1071 compound +,mice
R677 T1071 T1066 pobj mice,in
R678 T1072 T1035 punct .,found
R679 T1073 T1090 advmod Moreover,increased
R680 T1074 T1084 punct ",",+
R681 T1075 T1084 nsubj infiltration,+
R682 T1076 T1075 prep of,infiltration
R683 T1077 T1081 nummod CD8,cell
R684 T1078 T1081 nummod +,cell
R685 T1079 T1081 amod cytotoxic,cell
R686 T1080 T1081 compound T,cell
R687 T1081 T1076 pobj cell,of
R688 T1082 T1081 cc and,cell
R689 T1083 T1084 nmod CD57,+
R690 T1084 T1090 mark +,increased
R691 T1085 T1087 amod natural,cells
R692 T1086 T1087 compound killer,cells
R693 T1087 T1090 nsubjpass cells,increased
R694 T1131 T1130 cc and,NF-κB
R695 T1088 T1090 auxpass was,increased
R696 T1089 T1090 advmod significantly,increased
R697 T1090 T1090 ROOT increased,increased
R698 T1091 T1090 prep in,increased
R699 T1132 T1128 conj upregulation,inhibition
R700 T1092 T1093 compound melanoma,tumor
R701 T1093 T1091 pobj tumor,in
R702 T1094 T1093 cc and,tumor
R703 T1133 T1128 prep of,inhibition
R704 T1095 T1096 compound spleen,tissue
R705 T1096 T1093 conj tissue,tumor
R706 T1097 T1096 prep of,tissue
R707 T1098 T1102 nummod CCR5,mice
R708 T1099 T1102 nummod −,mice
R709 T1100 T1102 compound /,mice
R710 T1134 T1133 pobj IL-1Ra,of
R711 T1101 T1102 compound −,mice
R712 T1102 T1097 pobj mice,of
R713 T1103 T1090 prep compared,increased
R714 T1104 T1103 prep to,compared
R715 T1135 T1117 punct .,showed
R716 T1105 T1104 pobj that,to
R717 T1106 T1105 prep of,that
R718 T1107 T1111 nummod CCR5,mice
R719 T1108 T1111 nummod +,mice
R720 T1109 T1111 compound /,mice
R721 T1110 T1111 compound +,mice
R722 T1111 T1106 pobj mice,of
R723 T1112 T1090 punct .,increased
R724 T1113 T1117 advmod Therefore,showed
R725 T1114 T1117 punct ",",showed
R726 T1115 T1116 det these,results
R727 T1116 T1117 nsubj results,showed
R728 T1117 T1117 ROOT showed,showed
R729 T1118 T1121 mark that,caused
R730 T1119 T1120 amod CCR5,deficiency
R731 T1120 T1121 nsubj deficiency,caused
R732 T1121 T1117 ccomp caused,showed
R733 T1122 T1124 amod apoptotic,death
R734 T1123 T1124 compound cell,death
R735 T1124 T1121 dobj death,caused
R736 T1125 T1124 prep of,death
R737 T1126 T1125 pobj melanoma,of
R738 T1127 T1121 prep through,caused
R739 T1128 T1127 pobj inhibition,through
R740 T1129 T1128 prep of,inhibition
R7586 T11728 T11730 compound B16,cells
R7587 T11729 T11730 compound melanoma,cells
R7588 T11696 T11702 prep In,found
R7589 T11730 T11727 pobj cells,with
R7590 T11697 T11699 det the,study
R7591 T11698 T11699 amod present,study
R7592 T11699 T11696 pobj study,In
R7593 T11731 T11732 punct (,Figure
R7594 T11700 T11702 punct ",",found
R7595 T11732 T11730 appos Figure,cells
R7596 T11733 T11732 nummod 1A,Figure
R7597 T11701 T11702 nsubj we,found
R7598 T11702 T11702 ROOT found,found
R7599 T11734 T11733 cc and,1A
R7600 T11703 T11708 mark that,were
R7601 T11704 T11705 compound tumor,weight
R7602 T11735 T11733 conj 1B,1A
R7603 T11705 T11708 nsubj weight,were
R7604 T11706 T11705 cc and,weight
R7605 T11707 T11705 conj volume,weight
R7606 T11736 T11732 punct ),Figure
R7607 T11708 T11702 ccomp were,found
R7608 T11709 T11710 advmod much,smaller
R7609 T11737 T11723 punct .,/
R7610 T11710 T11708 acomp smaller,were
R7611 T11711 T11710 prep in,smaller
R7612 T11712 T11714 det the,−
R7613 T11738 T11741 det The,inhibition
R7614 T11713 T11714 compound CCR5,−
R7615 T11714 T11711 pobj −,in
R7616 T11739 T11741 compound tumor,inhibition
R7617 T11715 T11708 conj /,were
R7618 T11716 T11717 nummod −,mice
R7619 T11717 T11715 dobj mice,/
R7620 T11718 T11715 prep compared,/
R7621 T11740 T11741 compound growth,inhibition
R7622 T11719 T11718 prep to,compared
R7623 T11741 T11746 nsubj inhibition,/
R7624 T11720 T11722 det the,+
R7625 T11721 T11722 compound CCR5,+
R7626 T11722 T11723 dep +,/
R7627 T11723 T11702 conj /,found
R7628 T11724 T11725 nummod +,mice
R7629 T11742 T11741 prep in,inhibition
R7630 T11725 T11723 dobj mice,/
R7631 T11726 T11725 acl inoculated,mice
R7632 T11727 T11726 prep with,inoculated
R7633 T11743 T11745 det the,−
R7634 T11744 T11745 compound CCR5,−
R7635 T11745 T11742 pobj −,in
R7636 T11746 T11746 ROOT /,/
R7637 T11747 T11748 nummod −,mice
R7638 T11783 T11782 punct ",",proliferative
R7639 T11784 T11782 cc and,proliferative
R7640 T11748 T11750 nsubjpass mice,associated
R7641 T11785 T11786 npadvmod tumor,promoting
R7642 T11786 T11776 pcomp promoting,of
R7643 T11749 T11750 auxpass was,associated
R7644 T11787 T11786 dobj genes,promoting
R7645 T11788 T11787 punct (,genes
R7646 T11750 T11746 conj associated,/
R7647 T11789 T11787 appos Bcl-2,genes
R7648 T11790 T11789 cc and,Bcl-2
R7649 T11751 T11750 prep with,associated
R7650 T11791 T11789 conj C-IAP1,Bcl-2
R7651 T11792 T11791 punct ),C-IAP1
R7652 T11793 T11773 cc but,with
R7653 T11752 T11753 det the,inhibition
R7654 T11794 T11773 conj with,with
R7655 T11795 T11796 amod increased,expression
R7656 T11796 T11794 pobj expression,with
R7657 T11797 T11796 prep of,expression
R7658 T11753 T11751 pobj inhibition,with
R7659 T11798 T11801 poss their,genes
R7660 T11799 T11801 compound target,genes
R7661 T11800 T11801 compound apoptotic,genes
R7662 T11801 T11797 pobj genes,of
R7663 T11754 T11753 prep of,inhibition
R7664 T11802 T11804 punct ;,caspase-3
R7665 T11803 T11804 compound cleaved,caspase-3
R7666 T11804 T11804 ROOT caspase-3,caspase-3
R7667 T11755 T11756 advmod constitutively,activated
R7668 T11805 T11804 cc and,caspase-3
R7669 T11806 T11804 conj 9,caspase-3
R7670 T11807 T11806 punct ",",9
R7671 T11808 T11806 cc and,9
R7672 T11756 T11757 amod activated,NF-κB
R7673 T11809 T11806 conj Bax,9
R7674 T11810 T11812 punct (,3A-D
R7675 T11757 T11754 pobj NF-κB,of
R7676 T11811 T11812 compound Figure,3A-D
R7677 T11812 T11809 appos 3A-D,Bax
R7678 T11758 T11753 cc and,inhibition
R7679 T11813 T11812 punct ),3A-D
R7680 T11814 T11804 punct .,caspase-3
R7681 T11815 T11843 prep In,increased
R7682 T11816 T11817 det the,tumor
R7683 T11759 T11753 conj elevation,inhibition
R7684 T11817 T11815 pobj tumor,In
R7685 T11818 T11817 cc and,tumor
R7686 T11819 T11820 det the,spleen
R7687 T11820 T11817 conj spleen,tumor
R7688 T11821 T11843 punct ",",increased
R7689 T11822 T11823 det the,number
R7690 T11823 T11843 nsubjpass number,increased
R7691 T11760 T11759 prep of,elevation
R7692 T11761 T11760 pobj IL-1Ra,of
R7693 T11762 T11753 prep in,inhibition
R7694 T11824 T11823 prep of,number
R7695 T11825 T11829 amod cytotoxic,cells
R7696 T11763 T11765 det the,tissue
R7697 T11826 T11829 nmod CD8,cells
R7698 T11827 T11829 nummod +,cells
R7699 T11764 T11765 compound tumor,tissue
R7700 T11828 T11829 compound T,cells
R7701 T11829 T11824 pobj cells,of
R7702 T11830 T11823 punct ",",number
R7703 T11831 T11823 appos CD57,number
R7704 T11765 T11762 pobj tissue,in
R7705 T11832 T11835 nmod +,cells
R7706 T11833 T11835 amod natural,cells
R7707 T11766 T11750 punct .,associated
R7708 T11834 T11835 compound killer,cells
R7709 T11835 T11823 conj cells,number
R7710 T11836 T11835 punct ",",cells
R7711 T11837 T11835 cc and,cells
R7712 T11767 T11769 det This,activity
R7713 T11838 T11839 det the,levels
R7714 T11839 T11835 conj levels,cells
R7715 T11840 T11839 prep of,levels
R7716 T11768 T11769 amod anti-tumor,activity
R7717 T11841 T11840 pobj IL-1Ra,of
R7718 T11842 T11843 auxpass were,increased
R7719 T11843 T11843 ROOT increased,increased
R7720 T11769 T11772 nsubjpass activity,associated
R7721 T11844 T11845 punct (,Figure
R7722 T11845 T11843 npadvmod Figure,increased
R7723 T11770 T11772 auxpass was,associated
R7724 T11846 T11845 nummod 4,Figure
R7725 T11847 T11845 cc and,Figure
R7726 T11848 T11845 nummod 5,Figure
R7727 T11771 T11772 advmod also,associated
R7728 T11849 T11845 punct ),Figure
R7729 T11850 T11843 punct .,increased
R7730 T11772 T11804 ccomp associated,caspase-3
R7731 T11851 T11852 det These,findings
R7732 T11852 T11853 nsubj findings,suggest
R7733 T11853 T11853 ROOT suggest,suggest
R7734 T11854 T11858 mark that,inhibited
R7735 T11855 T11856 compound melanoma,growth
R7736 T11856 T11858 nsubjpass growth,inhibited
R7737 T11773 T11772 prep with,associated
R7738 T11857 T11858 auxpass was,inhibited
R7739 T11774 T11775 amod decreased,expression
R7740 T11858 T11853 ccomp inhibited,suggest
R7741 T11775 T11773 pobj expression,with
R7742 T11859 T11858 prep in,inhibited
R7743 T11860 T11862 det the,−
R7744 T11861 T11862 compound CCR5,−
R7745 T11776 T11775 prep of,expression
R7746 T11862 T11859 pobj −,in
R7747 T11863 T11853 conj /,suggest
R7748 T11864 T11865 nummod −,mice
R7749 T11777 T11778 amod NF-κB,target
R7750 T11865 T11863 dobj mice,/
R7751 T11866 T11863 punct ",",/
R7752 T11867 T11863 cc and,/
R7753 T11778 T11786 dative target,promoting
R7754 T11868 T11879 mark that,is
R7755 T11869 T11870 det the,elevation
R7756 T11779 T11782 amod anti-apoptotic,proliferative
R7757 T11870 T11879 nsubj elevation,is
R7758 T11871 T11870 prep of,elevation
R7759 T11872 T11871 pobj IL-1Ra,of
R7760 T11780 T11782 punct ",",proliferative
R7761 T11873 T11874 punct ",",accompanied
R7762 T11874 T11870 prep accompanied,elevation
R7763 T11875 T11874 prep with,accompanied
R7764 T11876 T11877 amod decreased,NF-κB
R7765 T11781 T11782 compound cell,proliferative
R7766 T11877 T11875 pobj NF-κB,with
R7767 T11878 T11879 punct ",",is
R7768 T11879 T11863 conj is,/
R7769 T11782 T11778 appos proliferative,target
R7770 T11880 T11879 acomp significant,is
R7771 T11881 T11880 prep in,significant
R7772 T11882 T11883 det the,inhibition
R7773 T11921 T11922 aux to,induce
R7774 T11883 T11881 pobj inhibition,in
R7775 T11884 T11883 prep of,inhibition
R7776 T11885 T11886 compound melanoma,growth
R7777 T11886 T11884 pobj growth,of
R7778 T11922 T11947 advcl induce,recognized
R7779 T11887 T11879 prep in,is
R7780 T11888 T11892 nummod CCR5,mice
R7781 T11923 T11924 det the,expression
R7782 T11889 T11892 nummod −,mice
R7783 T11890 T11892 nmod /,mice
R7784 T11891 T11892 amod −,mice
R7785 T11892 T11887 pobj mice,in
R7786 T11893 T11879 punct .,is
R7787 T11894 T11895 nsubj NF-κB,regulates
R7788 T11895 T11895 ROOT regulates,regulates
R7789 T11924 T11922 dobj expression,induce
R7790 T11896 T11897 det the,expression
R7791 T11897 T11895 dobj expression,regulates
R7792 T11898 T11897 prep of,expression
R7793 T11899 T11900 quantmod over,200
R7794 T11925 T11924 prep of,expression
R7795 T11900 T11901 nummod 200,genes
R7796 T11901 T11898 pobj genes,of
R7797 T11902 T11903 nsubj that,control
R7798 T11926 T11928 det a,array
R7799 T11903 T11901 relcl control,genes
R7800 T11904 T11906 det the,system
R7801 T11905 T11906 amod immune,system
R7802 T11927 T11928 amod large,array
R7803 T11906 T11903 dobj system,control
R7804 T11907 T11906 punct ",",system
R7805 T11908 T11909 compound cancer,cell
R7806 T11928 T11925 pobj array,of
R7807 T11909 T11910 compound cell,growth
R7808 T11910 T11906 conj growth,system
R7809 T11911 T11910 cc and,growth
R7810 T11929 T11928 prep of,array
R7811 T11912 T11910 conj inflammation,growth
R7812 T11913 T11915 nmod [,]
R7813 T11914 T11915 nummod 39,]
R7814 T11930 T11931 amod inflammatory,mediators
R7815 T11915 T11897 appos ],expression
R7816 T11916 T11895 punct .,regulates
R7817 T11931 T11929 pobj mediators,of
R7818 T11917 T11947 prep Because,recognized
R7819 T11918 T11917 pcomp of,Because
R7820 T11919 T11920 poss its,abilities
R7821 T11920 T11917 pobj abilities,Because
R7822 T11932 T11931 cc and,mediators
R7823 T11933 T11934 poss its,roles
R7824 T11934 T11931 conj roles,mediators
R7825 T11935 T11934 prep as,roles
R7826 T11936 T11938 amod core,factors
R7827 T12018 T11999 conj enhanced,inhibited
R7828 T11937 T11938 compound transcription,factors
R7829 T12019 T12018 punct .,enhanced
R7830 T12020 T12024 prep In,−
R7831 T11938 T11935 pobj factors,as
R7832 T12021 T12020 pobj addition,In
R7833 T12022 T12024 punct ",",−
R7834 T11939 T11928 prep in,array
R7835 T12023 T12024 nsubj CCR5,−
R7836 T12024 T12024 ROOT −,−
R7837 T12025 T12026 nummod /,−
R7838 T12026 T12027 nsubj −,prevented
R7839 T12027 T12024 ccomp prevented,−
R7840 T11940 T11942 amod diverse,responses
R7841 T12028 T12029 det the,phosphorylation
R7842 T12029 T12027 dobj phosphorylation,prevented
R7843 T12030 T12029 prep of,phosphorylation
R7844 T11941 T11942 amod immune,responses
R7845 T12031 T12030 pobj IκB,of
R7846 T12032 T12029 punct ",",phosphorylation
R7847 T12033 T12027 advcl accompanied,prevented
R7848 T11942 T11939 pobj responses,in
R7849 T12034 T12033 prep with,accompanied
R7850 T12035 T12036 det the,inhibition
R7851 T12036 T12034 pobj inhibition,with
R7852 T11943 T11947 punct ",",recognized
R7853 T12037 T12036 prep of,inhibition
R7854 T12038 T12039 det the,p50
R7855 T11944 T11947 nsubjpass NF-κB,recognized
R7856 T12039 T12037 pobj p50,of
R7857 T12040 T12039 cc and,p50
R7858 T12041 T12042 nummod p65,translocation
R7859 T11945 T11947 aux has,recognized
R7860 T12042 T12039 conj translocation,p50
R7861 T12043 T12033 prep into,accompanied
R7862 T12044 T12045 det the,nucleus
R7863 T11946 T11947 auxpass been,recognized
R7864 T12045 T12043 pobj nucleus,into
R7865 T12046 T12048 punct (,2A-C
R7866 T12047 T12048 compound Figure,2A-C
R7867 T11947 T11947 ROOT recognized,recognized
R7868 T12048 T12045 appos 2A-C,nucleus
R7869 T12049 T12048 punct ),2A-C
R7870 T12050 T12024 punct .,−
R7871 T11948 T11947 prep as,recognized
R7872 T12051 T12052 amod Many,tumors
R7873 T12052 T12058 nsubj tumors,increased
R7874 T11949 T11951 det a,factor
R7875 T12053 T12052 punct ",",tumors
R7876 T12054 T12052 prep including,tumors
R7877 T12055 T12054 pobj melanoma,including
R7878 T12056 T12052 punct ",",tumors
R7879 T11950 T11951 amod major,factor
R7880 T12057 T12058 aux have,increased
R7881 T12058 T12058 ROOT increased,increased
R7882 T12059 T12058 dobj levels,increased
R7883 T11951 T11948 pobj factor,as
R7884 T12060 T12059 prep of,levels
R7885 T12061 T12062 compound NF-κB,[
R7886 T12062 T12060 pobj [,of
R7887 T12063 T12064 nummod 40,]
R7888 T12064 T12059 appos ],levels
R7889 T11952 T11951 amod responsible,factor
R7890 T12065 T12064 punct ",",]
R7891 T12066 T12067 nsubj which,is
R7892 T12067 T12064 relcl is,]
R7893 T11953 T11952 prep for,responsible
R7894 T12068 T12067 acomp likely,is
R7895 T12069 T12068 xcomp acting,likely
R7896 T12070 T12069 prep as,acting
R7897 T11954 T11956 amod cytokine-associated,development
R7898 T12071 T12073 det a,factor
R7899 T12072 T12073 compound survival,factor
R7900 T12073 T12070 pobj factor,as
R7901 T11955 T11956 compound cancer,development
R7902 T12074 T12073 prep for,factor
R7903 T12075 T12076 compound melanoma,growth
R7904 T12076 T12074 pobj growth,for
R7905 T11956 T11953 pobj development,for
R7906 T12077 T12058 punct .,increased
R7907 T12078 T12091 advmod Thus,are
R7908 T12079 T12091 punct ",",are
R7909 T11957 T11956 cc or,development
R7910 T12080 T12081 det the,inhibitions
R7911 T12081 T12091 nsubj inhibitions,are
R7912 T12082 T12081 prep of,inhibitions
R7913 T11958 T11959 amod anti-tumor,immunity
R7914 T12083 T12084 amod NF-κB,activity
R7915 T12084 T12082 pobj activity,of
R7916 T12085 T12084 cc and,activity
R7917 T11959 T11956 conj immunity,development
R7918 T12086 T12087 det the,expression
R7919 T12087 T12084 conj expression,activity
R7920 T11960 T11947 punct .,recognized
R7921 T12088 T12087 prep of,expression
R7922 T12089 T12090 compound target,genes
R7923 T12090 T12088 pobj genes,of
R7924 T11961 T11970 prep In,/
R7925 T12091 T12091 ROOT are,are
R7926 T12092 T12091 acomp critical,are
R7927 T11962 T11965 det the,tissues
R7928 T11963 T11965 compound melanoma,tissues
R7929 T12093 T12092 prep in,critical
R7930 T11964 T11965 compound tumor,tissues
R7931 T12094 T12095 det the,inhibition
R7932 T12095 T12093 pobj inhibition,in
R7933 T12096 T12095 prep of,inhibition
R7934 T11965 T11961 pobj tissues,In
R7935 T12097 T12098 compound tumor,growth
R7936 T12098 T12096 pobj growth,of
R7937 T12099 T12091 prep in,are
R7938 T12100 T12104 nummod CCR5,mice
R7939 T11966 T11965 prep of,tissues
R7940 T12101 T12104 nummod −,mice
R7941 T12102 T12104 nmod /,mice
R7942 T12103 T12104 compound −,mice
R7943 T12104 T12099 pobj mice,in
R7944 T11967 T11969 det the,−
R7945 T12105 T12091 punct .,are
R7946 T12106 T12109 mark Although,is
R7947 T12107 T12108 det the,mechanism
R7948 T11968 T11969 compound CCR5,−
R7949 T12108 T12109 nsubj mechanism,is
R7950 T12109 T12123 advcl is,is
R7951 T12110 T12111 neg not,clear
R7952 T11969 T11966 pobj −,of
R7953 T12111 T12109 acomp clear,is
R7954 T12112 T12123 prep as,is
R7955 T12113 T12112 pcomp to,as
R7956 T11970 T11999 advcl /,inhibited
R7957 T12114 T12116 advmod how,−
R7958 T11971 T11972 nummod −,mice
R7959 T11972 T11970 dobj mice,/
R7960 T11973 T11999 punct ",",inhibited
R7961 T12115 T12116 nsubj CCR5,−
R7962 T11974 T11975 det the,expression
R7963 T12116 T12123 advcl −,is
R7964 T12117 T12119 nummod /,downregulates
R7965 T11975 T11999 nsubjpass expression,inhibited
R7966 T11976 T11975 prep of,expression
R7967 T11977 T11981 amod NF-κB,genes
R7968 T12118 T12119 compound −,downregulates
R7969 T11978 T11979 compound target,cell
R7970 T12119 T12120 compound downregulates,NF-κB
R7971 T12120 T12116 dobj NF-κB,−
R7972 T12121 T12123 punct ",",is
R7973 T11979 T11980 compound cell,death
R7974 T12122 T12123 nsubj it,is
R7975 T12123 T12123 ROOT is,is
R7976 T12124 T12123 acomp noteworthy,is
R7977 T11980 T11981 compound death,genes
R7978 T12125 T12128 mark that,activated
R7979 T12126 T12128 nsubjpass NF-κB,activated
R7980 T11981 T11976 pobj genes,of
R7981 T12127 T12128 auxpass is,activated
R7982 T12128 T12123 ccomp activated,is
R7983 T12129 T12128 cc or,activated
R7984 T11982 T11999 punct (,inhibited
R7985 T12130 T12128 conj inactivated,activated
R7986 T12131 T12130 agent by,inactivated
R7987 T12132 T12133 amod many,cytokines
R7988 T12133 T12131 pobj cytokines,by
R7989 T12134 T12123 punct .,is
R7990 T12135 T12136 amod Numerous,studies
R7991 T11983 T11999 nsubjpass Bax,inhibited
R7992 T12136 T12137 nsubj studies,showed
R7993 T12137 T12137 ROOT showed,showed
R7994 T11984 T11983 punct ",",Bax
R7995 T12138 T12140 mark that,affect
R7996 T12139 T12140 nsubj cytokine,affect
R7997 T12140 T12137 ccomp affect,showed
R7998 T11985 T11983 conj caspase-3,Bax
R7999 T12141 T12142 compound tumor,growth
R8000 T12142 T12140 dobj growth,affect
R8001 T12143 T12140 prep by,affect
R8002 T11986 T11985 cc and,caspase-3
R8003 T12144 T12143 pcomp regulating,by
R8004 T12145 T12144 dobj NF-κB,regulating
R8005 T11987 T11985 conj 9,caspase-3
R8006 T12146 T12137 punct .,showed
R8007 T12147 T12148 amod Inflammatory,cytokines
R8008 T12148 T12157 nsubj cytokines,activate
R8009 T11988 T11987 punct ),9
R8010 T12149 T12148 punct ",",cytokines
R8011 T12150 T12148 prep including,cytokines
R8012 T11989 T11985 cc and,caspase-3
R8013 T12151 T12150 pobj IL-1,including
R8014 T12152 T12151 punct ",",IL-1
R8015 T12153 T12151 conj IL-6,IL-1
R8016 T11990 T11993 det the,activity
R8017 T12154 T12153 cc and,IL-6
R8018 T12155 T12153 conj IL-8,IL-6
R8019 T12156 T12148 punct ",",cytokines
R8020 T11991 T11993 compound DNA,activity
R8021 T12157 T12157 ROOT activate,activate
R8022 T12158 T12159 amod NF-κB,pathways
R8023 T12159 T12157 dobj pathways,activate
R8024 T11992 T11993 amod binding,activity
R8025 T12160 T12159 prep in,pathways
R8026 T12161 T12162 compound tumor,cells
R8027 T12162 T12160 pobj cells,in
R8028 T11993 T11985 conj activity,caspase-3
R8029 T12163 T12165 nmod [,]
R8030 T12164 T12165 nummod 41,]
R8031 T11994 T11993 prep of,activity
R8032 T12165 T12159 conj ],pathways
R8033 T12166 T12157 punct .,activate
R8034 T12167 T12175 det The,known
R8035 T11995 T11994 pobj NF-κB,of
R8036 T12168 T12175 nsubjpass interleukin,known
R8037 T12169 T12168 nummod 10,interleukin
R8038 T12170 T12168 punct (,interleukin
R8039 T11996 T11997 punct ",",were
R8040 T12171 T12168 appos IL-10,interleukin
R8041 T11997 T11999 auxpass were,inhibited
R8042 T12172 T12168 punct ),interleukin
R8043 T12173 T12175 auxpass is,known
R8044 T12174 T12175 advmod well,known
R8045 T11998 T11999 advmod significantly,inhibited
R8046 T12175 T12175 ROOT known,known
R8047 T12176 T12175 prep as,known
R8048 T12177 T12179 det an,factor
R8049 T11999 T11999 ROOT inhibited,inhibited
R8050 T12178 T12179 amod anti-tumor,factor
R8051 T12179 T12176 pobj factor,as
R8052 T12000 T11999 punct ",",inhibited
R8053 T12180 T12182 advmod as,as
R8054 T12181 T12182 advmod well,as
R8055 T12182 T12179 cc as,factor
R8056 T12001 T11999 cc but,inhibited
R8057 T12183 T12185 det an,factor
R8058 T12184 T12185 amod anti-inflammatory,factor
R8059 T12002 T12003 det the,expression
R8060 T12185 T12179 conj factor,factor
R8061 T12186 T12188 nmod [,]
R8062 T12187 T12188 nummod 42,]
R8063 T12003 T12018 nsubjpass expression,enhanced
R8064 T12188 T12185 appos ],factor
R8065 T12189 T12188 punct ",",]
R8066 T12190 T12192 nmod [,]
R8067 T12004 T12003 prep of,expression
R8068 T12191 T12192 nummod 43,]
R8069 T12192 T12188 appos ],]
R8070 T12193 T12175 punct .,known
R8071 T12005 T12006 compound cell,death
R8072 T12194 T12195 amod IL-10,inhibits
R8073 T12195 T12197 nsubj inhibits,activated
R8074 T12196 T12197 advmod constitutively,activated
R8075 T12006 T12004 pobj death,of
R8076 T12197 T12197 ROOT activated,activated
R8077 T12198 T12199 compound NF-κB,both
R8078 T12199 T12200 preconj both,in
R8079 T12007 T12010 amod inhibitory,genes
R8080 T12200 T12197 prep in,activated
R8081 T12201 T12204 amod vitro,]
R8082 T12202 T12204 nmod [,]
R8083 T12008 T12010 compound NF-κB,genes
R8084 T12203 T12204 nummod 44,]
R8085 T12204 T12200 pobj ],in
R8086 T12009 T12010 compound target,genes
R8087 T12205 T12200 cc and,in
R8088 T12206 T12200 conj in,in
R8089 T12207 T12208 compound vivo,[
R8090 T12208 T12206 pobj [,in
R8091 T12209 T12210 nummod 45,]
R8092 T12210 T12208 appos ],[
R8093 T12010 T12018 nsubjpass genes,enhanced
R8094 T12211 T12197 punct .,activated
R8095 T12011 T12010 punct ",",genes
R8096 T12012 T12013 amod such,as
R8097 T12212 T12218 nsubj Inhibition,contributes
R8098 T12013 T12010 prep as,genes
R8099 T12213 T12212 prep of,Inhibition
R8100 T12014 T12013 pobj Bcl-2,as
R8101 T12214 T12213 pobj NF-κB,of
R8102 T12215 T12212 prep by,Inhibition
R8103 T12216 T12217 det the,IL-10
R8104 T12217 T12215 pobj IL-10,by
R8105 T12218 T12218 ROOT contributes,contributes
R8106 T12015 T12014 cc and,Bcl-2
R8107 T12219 T12218 prep to,contributes
R8108 T12220 T12222 det the,effects
R8109 T12221 T12222 amod anti-tumor,effects
R8110 T12016 T12018 nsubjpass cIAP,enhanced
R8111 T12222 T12219 pobj effects,to
R8112 T12223 T12222 prep through,effects
R8113 T12224 T12225 det the,activation
R8114 T12017 T12018 auxpass were,enhanced
R8115 T12225 T12223 pobj activation,through
R8116 T12226 T12225 prep of,activation
R8117 T12227 T12226 pobj caspase-3,of
R8118 T12309 T12310 aux to,regulate
R8119 T12228 T12227 cc and,caspase-3
R8120 T12229 T12227 conj apoptosis,caspase-3
R8121 T12230 T12225 prep in,activation
R8122 T12231 T12232 amod Colon26-bearing,mice
R8123 T12232 T12230 pobj mice,in
R8124 T12310 T12308 xcomp regulate,is
R8125 T12233 T12235 nmod [,]
R8126 T12234 T12235 nummod 43,]
R8127 T12235 T12225 appos ],activation
R8128 T12311 T12313 det the,effects
R8129 T12236 T12218 punct .,contributes
R8130 T12237 T12242 advmod Similarly,demonstrated
R8131 T12238 T12242 punct ",",demonstrated
R8132 T12312 T12313 amod pleiotropic,effects
R8133 T12239 T12240 amod several,studies
R8134 T12240 T12242 nsubj studies,demonstrated
R8135 T12241 T12242 aux have,demonstrated
R8136 T12313 T12310 dobj effects,regulate
R8137 T12242 T12242 ROOT demonstrated,demonstrated
R8138 T12243 T12244 det the,ability
R8139 T12244 T12242 dobj ability,demonstrated
R8140 T12245 T12244 prep of,ability
R8141 T12246 T12245 pobj IL-1Ra,of
R8142 T12247 T12248 aux to,abrogate
R8143 T12314 T12313 prep of,effects
R8144 T12248 T12244 acl abrogate,ability
R8145 T12249 T12251 det the,effects
R8146 T12315 T12314 pobj IL-1,of
R8147 T12316 T12310 prep by,regulate
R8148 T12250 T12251 amod proinflammatory,effects
R8149 T12317 T12318 advmod competitively,blocking
R8150 T12251 T12248 dobj effects,abrogate
R8151 T12252 T12251 prep of,effects
R8152 T12318 T12316 pcomp blocking,by
R8153 T12253 T12254 compound IL-1,[
R8154 T12254 T12252 pobj [,of
R8155 T12255 T12256 nummod 46,]
R8156 T12319 T12320 poss its,functions
R8157 T12256 T12251 conj ],effects
R8158 T12257 T12242 punct .,demonstrated
R8159 T12258 T12261 nsubjpass It,reported
R8160 T12320 T12318 dobj functions,blocking
R8161 T12259 T12261 aux has,reported
R8162 T12260 T12261 auxpass been,reported
R8163 T12321 T12323 nmod [,]
R8164 T12261 T12261 ROOT reported,reported
R8165 T12262 T12264 mark that,induces
R8166 T12263 T12264 nsubj IL-1,induces
R8167 T12322 T12323 nummod 47,]
R8168 T12264 T12261 ccomp induces,reported
R8169 T12265 T12266 det the,activation
R8170 T12266 T12264 dobj activation,induces
R8171 T12323 T12318 dobj ],blocking
R8172 T12267 T12266 prep of,activation
R8173 T12268 T12267 pobj NF-κB,of
R8174 T12269 T12266 prep in,activation
R8175 T12324 T12301 punct .,indicate
R8176 T12270 T12271 amod several,cancers
R8177 T12271 T12269 pobj cancers,in
R8178 T12272 T12261 punct ",",reported
R8179 T12325 T12326 det The,ability
R8180 T12273 T12261 cc and,reported
R8181 T12274 T12261 conj increases,reported
R8182 T12275 T12276 compound cell,cycle
R8183 T12326 T12334 nsubj ability,is
R8184 T12276 T12277 compound cycle,progression
R8185 T12277 T12274 dobj progression,increases
R8186 T12278 T12274 punct ",",increases
R8187 T12327 T12326 prep of,ability
R8188 T12279 T12274 cc and,increases
R8189 T12280 T12281 det the,suppression
R8190 T12281 T12274 conj suppression,increases
R8191 T12282 T12281 prep of,suppression
R8192 T12283 T12285 amod apoptotic,death
R8193 T12284 T12285 compound cell,death
R8194 T12328 T12327 pobj IL-1,of
R8195 T12285 T12282 pobj death,of
R8196 T12286 T12281 acl leading,suppression
R8197 T12287 T12286 prep to,leading
R8198 T12329 T12330 aux to,induce
R8199 T12288 T12289 compound tumor,promotion
R8200 T12289 T12287 pobj promotion,to
R8201 T12290 T12261 punct .,reported
R8202 T12330 T12326 acl induce,ability
R8203 T12291 T12292 det The,results
R8204 T12292 T12301 nsubj results,indicate
R8205 T12331 T12333 poss its,antagonist
R8206 T12293 T12292 prep of,results
R8207 T12294 T12295 amod various,studies
R8208 T12295 T12293 pobj studies,of
R8209 T12332 T12333 amod own,antagonist
R8210 T12296 T12292 prep over,results
R8211 T12297 T12300 det the,years
R8212 T12298 T12300 amod past,years
R8213 T12333 T12330 dobj antagonist,induce
R8214 T12299 T12300 nummod 10,years
R8215 T12300 T12296 pobj years,over
R8216 T12334 T12334 ROOT is,is
R8217 T12301 T12301 ROOT indicate,indicate
R8218 T12302 T12308 mark that,is
R8219 T12303 T12305 det the,function
R8220 T12335 T12334 prep of,is
R8221 T12304 T12305 amod major,function
R8222 T12305 T12308 nsubj function,is
R8223 T12336 T12335 pobj interest,of
R8224 T12306 T12305 prep of,function
R8225 T12307 T12306 pobj IL-1Ra,of
R8226 T12308 T12301 ccomp is,indicate
R8227 T12337 T12336 prep in,interest
R8228 T12338 T12337 pcomp understanding,in
R8229 T12339 T12340 det the,regulation
R8230 T12406 T12407 compound tumor,progression
R8231 T12407 T12405 dobj progression,inhibit
R8232 T12340 T12338 dobj regulation,understanding
R8233 T12408 T12407 prep in,progression
R8234 T12341 T12340 cc and,regulation
R8235 T12409 T12408 pobj prostate,in
R8236 T12410 T12409 punct ",",prostate
R8237 T12342 T12340 conj dysregulation,regulation
R8238 T12411 T12409 conj breast,prostate
R8239 T12412 T12411 punct ",",breast
R8240 T12413 T12411 cc and,breast
R8241 T12414 T12415 compound skin,cancer
R8242 T12415 T12411 conj cancer,breast
R8243 T12416 T12418 nmod [,]
R8244 T12343 T12340 prep of,regulation
R8245 T12417 T12418 nummod 14,]
R8246 T12418 T12407 appos ],progression
R8247 T12344 T12345 amod IL-1,signaling
R8248 T12419 T12418 punct ",",]
R8249 T12420 T12422 nmod [,]
R8250 T12421 T12422 nummod 15,]
R8251 T12345 T12343 pobj signaling,of
R8252 T12422 T12418 conj ],]
R8253 T12423 T12422 punct ",",]
R8254 T12346 T12340 prep in,regulation
R8255 T12424 T12422 conj [,]
R8256 T12425 T12426 nummod 16,]
R8257 T12426 T12422 conj ],]
R8258 T12427 T12403 punct .,shown
R8259 T12347 T12350 amod normal,tissue
R8260 T12428 T12429 amod Intracellular,IL-1Ra
R8261 T12429 T12433 nsubj IL-1Ra,inhibits
R8262 T12430 T12431 punct (,icIL-1Ra
R8263 T12348 T12347 cc and,normal
R8264 T12431 T12429 appos icIL-1Ra,IL-1Ra
R8265 T12432 T12431 punct ),icIL-1Ra
R8266 T12433 T12433 ROOT inhibits,inhibits
R8267 T12434 T12433 dobj IL-6,inhibits
R8268 T12349 T12347 conj diseased,normal
R8269 T12435 T12434 cc and,IL-6
R8270 T12436 T12437 amod IL-8,production
R8271 T12437 T12434 conj production,IL-6
R8272 T12350 T12346 pobj tissue,in
R8273 T12438 T12437 prep in,production
R8274 T12439 T12440 amod Caco-2,cells
R8275 T12440 T12438 pobj cells,in
R8276 T12351 T12334 punct .,is
R8277 T12441 T12433 prep by,inhibits
R8278 T12442 T12441 pcomp blocking,by
R8279 T12443 T12444 amod NF-κB,pathways
R8280 T12352 T12357 nsubj Up-regulation,represents
R8281 T12444 T12442 dobj pathways,blocking
R8282 T12445 T12447 nmod [,]
R8283 T12446 T12447 nummod 37,]
R8284 T12353 T12352 prep of,Up-regulation
R8285 T12447 T12442 dobj ],blocking
R8286 T12448 T12433 punct .,inhibits
R8287 T12449 T12450 nsubj We,found
R8288 T12354 T12356 det the,antagonist
R8289 T12450 T12450 ROOT found,found
R8290 T12451 T12458 mark that,elevated
R8291 T12452 T12453 det the,levels
R8292 T12453 T12458 nsubjpass levels,elevated
R8293 T12454 T12453 prep of,levels
R8294 T12455 T12454 pobj IL-1Ra,of
R8295 T12355 T12356 compound receptor,antagonist
R8296 T12456 T12458 auxpass were,elevated
R8297 T12457 T12458 advmod significantly,elevated
R8298 T12458 T12450 ccomp elevated,found
R8299 T12459 T12458 prep in,elevated
R8300 T12356 T12353 pobj antagonist,of
R8301 T12460 T12462 det the,tissues
R8302 T12461 T12462 compound tumor,tissues
R8303 T12462 T12459 pobj tissues,in
R8304 T12357 T12357 ROOT represents,represents
R8305 T12463 T12462 prep of,tissues
R8306 T12464 T12468 nummod CCR5,mice
R8307 T12465 T12468 nummod −,mice
R8308 T12358 T12359 det a,mechanism
R8309 T12466 T12468 compound /,mice
R8310 T12467 T12468 compound −,mice
R8311 T12468 T12463 pobj mice,of
R8312 T12359 T12357 dobj mechanism,represents
R8313 T12469 T12468 acl inoculated,mice
R8314 T12470 T12469 prep with,inoculated
R8315 T12471 T12473 compound B16,cells
R8316 T12360 T12359 prep for,mechanism
R8317 T12472 T12473 compound melanoma,cells
R8318 T12473 T12470 pobj cells,with
R8319 T12474 T12450 punct .,found
R8320 T12361 T12360 pcomp turning,for
R8321 T12475 T12480 advcl Taken,indicate
R8322 T12476 T12475 advmod together,Taken
R8323 T12477 T12480 punct ",",indicate
R8324 T12362 T12361 prt off,turning
R8325 T12478 T12479 det these,data
R8326 T12479 T12480 nsubj data,indicate
R8327 T12363 T12361 dobj IL-1,turning
R8328 T12480 T12480 ROOT indicate,indicate
R8329 T12481 T12485 nsubjpass IL-1Ra,involved
R8330 T12482 T12485 aux could,involved
R8331 T12364 T12361 conj signaling,turning
R8332 T12483 T12485 auxpass be,involved
R8333 T12365 T12364 cc and,signaling
R8334 T12484 T12485 advmod critically,involved
R8335 T12366 T12364 conj creating,signaling
R8336 T12485 T12480 ccomp involved,indicate
R8337 T12486 T12485 prep in,involved
R8338 T12367 T12369 det a,state
R8339 T12368 T12369 amod temporary,state
R8340 T12487 T12490 det the,inhibition
R8341 T12488 T12489 compound tumor,growth
R8342 T12489 T12490 compound growth,inhibition
R8343 T12369 T12366 dobj state,creating
R8344 T12490 T12486 pobj inhibition,in
R8345 T12491 T12490 prep of,inhibition
R8346 T12492 T12496 nummod CCR5,mice
R8347 T12370 T12369 prep of,state
R8348 T12493 T12496 nummod −,mice
R8349 T12494 T12496 nmod /,mice
R8350 T12371 T12370 pobj refractoriness,of
R8351 T12495 T12496 compound −,mice
R8352 T12496 T12491 pobj mice,of
R8353 T12497 T12485 prep through,involved
R8354 T12372 T12357 punct .,represents
R8355 T12498 T12499 det the,inactivation
R8356 T12499 T12497 pobj inactivation,through
R8357 T12500 T12499 prep of,inactivation
R8358 T12501 T12500 pobj NF-κB,of
R8359 T12373 T12375 det The,expression
R8360 T12502 T12499 prep in,inactivation
R8361 T12374 T12375 amod elevated,expression
R8362 T12375 T12387 nsubj expression,suggests
R8363 T12376 T12375 prep of,expression
R8364 T12377 T12376 pobj IL-1Ra,of
R8365 T12378 T12375 punct ",",expression
R8366 T12503 T12505 det the,study
R8367 T12504 T12505 amod present,study
R8368 T12505 T12502 pobj study,in
R8369 T12379 T12375 prep without,expression
R8370 T12506 T12480 punct .,indicate
R8371 T12507 T12508 nummod CCR5,increases
R8372 T12380 T12381 det any,change
R8373 T12508 T12516 nsubj increases,inhibits
R8374 T12509 T12510 compound tumor,growth
R8375 T12510 T12508 dobj growth,increases
R8376 T12381 T12379 pobj change,without
R8377 T12511 T12508 prep in,increases
R8378 T12512 T12514 det a,model
R8379 T12513 T12514 amod local,model
R8380 T12382 T12381 prep of,change
R8381 T12514 T12511 pobj model,in
R8382 T12515 T12508 cc and,increases
R8383 T12383 T12382 pobj IL-1,of
R8384 T12516 T12516 ROOT inhibits,inhibits
R8385 T12517 T12518 det the,efficacy
R8386 T12518 T12516 dobj efficacy,inhibits
R8387 T12384 T12381 prep in,change
R8388 T12519 T12518 prep of,efficacy
R8389 T12520 T12523 det a,vaccine
R8390 T12521 T12523 amod dendrite,vaccine
R8391 T12522 T12523 compound cell,vaccine
R8392 T12523 T12519 pobj vaccine,of
R8393 T12524 T12518 prep in,efficacy
R8394 T12385 T12384 pobj tumors,in
R8395 T12525 T12529 nummod CCR5,mice
R8396 T12526 T12529 nummod +,mice
R8397 T12527 T12529 compound /,mice
R8398 T12386 T12387 punct ",",suggests
R8399 T12528 T12529 compound +,mice
R8400 T12529 T12524 pobj mice,in
R8401 T12530 T12516 prep compared,inhibits
R8402 T12387 T12387 ROOT suggests,suggests
R8403 T12531 T12530 prep with,compared
R8404 T12532 T12536 nummod CCR5,mice
R8405 T12533 T12536 nummod −,mice
R8406 T12388 T12394 mark that,dysregulated
R8407 T12534 T12536 compound /,mice
R8408 T12535 T12536 compound −,mice
R8409 T12536 T12531 pobj mice,with
R8410 T12537 T12539 nmod [,]
R8411 T12389 T12391 det the,system
R8412 T12538 T12539 nummod 10,]
R8413 T12539 T12536 appos ],mice
R8414 T12390 T12391 amod IL-1-signaling,system
R8415 T12540 T12516 punct .,inhibits
R8416 T12541 T12542 compound Cheng,J
R8417 T12542 T12546 nsubj J,examined
R8418 T12391 T12394 nsubjpass system,dysregulated
R8419 T12543 T12542 cc and,J
R8420 T12544 T12542 conj Sung,J
R8421 T12545 T12542 conj RS,J
R8422 T12392 T12394 aux may,dysregulated
R8423 T12546 T12546 ROOT examined,examined
R8424 T12547 T12548 det the,effect
R8425 T12393 T12394 auxpass be,dysregulated
R8426 T12548 T12546 dobj effect,examined
R8427 T12549 T12548 prep of,effect
R8428 T12550 T12549 pobj CCR5,of
R8429 T12394 T12387 ccomp dysregulated,suggests
R8430 T12551 T12548 prep on,effect
R8431 T12552 T12554 det the,response
R8432 T12553 T12554 amod immune,response
R8433 T12395 T12394 agent by,dysregulated
R8434 T12554 T12551 pobj response,on
R8435 T12555 T12554 prep to,response
R8436 T12556 T12557 compound adenovirus,vectors
R8437 T12396 T12395 pobj IL-1Ra,by
R8438 T12557 T12555 pobj vectors,to
R8439 T12558 T12557 cc and,vectors
R8440 T12559 T12560 compound graft,function
R8441 T12560 T12557 conj function,vectors
R8442 T12561 T12554 prep in,response
R8443 T12562 T12565 det an,model
R8444 T12397 T12394 prep in,dysregulated
R8445 T12563 T12565 compound islet,model
R8446 T12564 T12565 compound transplant,model
R8447 T12565 T12561 pobj model,in
R8448 T12398 T12397 pobj tumors,in
R8449 T12399 T12387 punct .,suggests
R8450 T12566 T12546 punct .,examined
R8451 T12400 T12403 nsubjpass IL-1Ra,shown
R8452 T12567 T12568 nsubj They,found
R8453 T12568 T12568 ROOT found,found
R8454 T12569 T12574 mark that,prevent
R8455 T12401 T12403 aux has,shown
R8456 T12570 T12571 nummod CCR5,absence
R8457 T12571 T12574 nsubj absence,prevent
R8458 T12402 T12403 auxpass been,shown
R8459 T12572 T12574 aux does,prevent
R8460 T12573 T12574 neg not,prevent
R8461 T12574 T12568 ccomp prevent,found
R8462 T12403 T12403 ROOT shown,shown
R8463 T12575 T12578 det the,response
R8464 T12576 T12578 amod local,response
R8465 T12404 T12405 aux to,inhibit
R8466 T12577 T12578 amod immune,response
R8467 T12578 T12574 dobj response,prevent
R8468 T12579 T12580 aux to,adenovirus
R8469 T12405 T12403 xcomp inhibit,shown
R8470 T12580 T12574 advcl adenovirus,prevent
R8471 T12581 T12582 compound transduction,[
R8472 T12600 T12594 prep by,disruption
R8473 T12582 T12580 dobj [,adenovirus
R8474 T12583 T12584 nummod 48,]
R8475 T12584 T12582 appos ],[
R8476 T12585 T12568 punct .,found
R8477 T12586 T12592 advmod Additionally,suggested
R8478 T12601 T12600 pcomp reducing,by
R8479 T12587 T12592 punct ",",suggested
R8480 T12588 T12589 compound Tan,MC
R8481 T12589 T12591 compound MC,al.
R8482 T12602 T12603 nummod CCL5,production
R8483 T12590 T12591 compound et,al.
R8484 T12591 T12592 nsubj al.,suggested
R8485 T12592 T12592 ROOT suggested,suggested
R8486 T12593 T12619 mark that,reduced
R8487 T12603 T12601 dobj production,reducing
R8488 T12594 T12619 nsubj disruption,reduced
R8489 T12595 T12594 prep of,disruption
R8490 T12596 T12595 pobj CCR5/CCL5,of
R8491 T12597 T12594 acl signaling,disruption
R8492 T12598 T12597 punct ",",signaling
R8493 T12599 T12600 advmod either,by
R8494 T12604 T12603 prep by,production
R8495 T12605 T12606 compound tumor,cells
R8496 T12606 T12604 pobj cells,by
R8497 T12607 T12604 cc or,by
R8498 T12697 T12701 amod +,cells
R8499 T12698 T12701 amod positive,cells
R8500 T12608 T12604 conj by,by
R8501 T12699 T12700 compound T,Lymphocytes
R8502 T12700 T12701 compound Lymphocytes,cells
R8503 T12609 T12610 amod systemic,administration
R8504 T12701 T12694 appos cells,cells
R8505 T12702 T12694 punct ),cells
R8506 T12610 T12608 pobj administration,by
R8507 T12703 T12690 cc and,number
R8508 T12704 T12706 amod natural,cells
R8509 T12705 T12706 compound killer,cells
R8510 T12611 T12610 prep of,administration
R8511 T12706 T12690 conj cells,number
R8512 T12707 T12690 punct (,number
R8513 T12708 T12711 nmod CD57,cells
R8514 T12612 T12614 det a,inhibitor
R8515 T12709 T12711 amod positive,cells
R8516 T12710 T12711 compound NK,cells
R8517 T12711 T12690 appos cells,number
R8518 T12712 T12690 punct ),number
R8519 T12613 T12614 compound CCR5,inhibitor
R8520 T12713 T12690 punct ",",number
R8521 T12714 T12716 advmod as,as
R8522 T12614 T12611 pobj inhibitor,of
R8523 T12715 T12716 advmod well,as
R8524 T12716 T12690 cc as,number
R8525 T12717 T12718 amod dendrite,cells
R8526 T12615 T12614 punct (,inhibitor
R8527 T12718 T12690 conj cells,number
R8528 T12719 T12687 punct ",",have
R8529 T12720 T12687 prep in,have
R8530 T12616 T12614 appos TAK-779,inhibitor
R8531 T12721 T12722 compound spleen,tissues
R8532 T12617 T12614 punct ),inhibitor
R8533 T12722 T12720 pobj tissues,in
R8534 T12618 T12594 punct ",",disruption
R8535 T12723 T12687 prep compared,have
R8536 T12724 T12723 prep to,compared
R8537 T12619 T12592 ccomp reduced,suggested
R8538 T12725 T12724 pobj those,to
R8539 T12726 T12725 prep without,those
R8540 T12620 T12626 nmod Treg,migration
R8541 T12727 T12728 compound melanoma,cells
R8542 T12728 T12726 pobj cells,without
R8543 T12729 T12674 punct .,found
R8544 T12730 T12737 cc But,/
R8545 T12731 T12732 det the,lymphocytes
R8546 T12621 T12620 punct (,Treg
R8547 T12732 T12737 nsubj lymphocytes,/
R8548 T12733 T12732 prep of,lymphocytes
R8549 T12734 T12736 det the,−
R8550 T12735 T12736 compound CCR5,−
R8551 T12622 T12624 amod regulatory,cells
R8552 T12736 T12733 pobj −,of
R8553 T12737 T12737 ROOT /,/
R8554 T12623 T12624 compound T,cells
R8555 T12738 T12739 nummod −,mice
R8556 T12739 T12742 nsubj mice,decrease
R8557 T12740 T12742 aux did,decrease
R8558 T12624 T12620 appos cells,Treg
R8559 T12741 T12742 neg not,decrease
R8560 T12742 T12737 ccomp decrease,/
R8561 T12743 T12744 advmod when,injected
R8562 T12625 T12620 punct ),Treg
R8563 T12744 T12742 advcl injected,decrease
R8564 T12745 T12744 prep with,injected
R8565 T12746 T12747 compound melanoma,cells
R8566 T12747 T12745 pobj cells,with
R8567 T12626 T12619 dobj migration,reduced
R8568 T12748 T12737 punct .,/
R8569 T12749 T12750 det These,differences
R8570 T12627 T12619 prep to,reduced
R8571 T12750 T12759 nsubj differences,/
R8572 T12751 T12750 prep of,differences
R8573 T12752 T12754 det the,response
R8574 T12753 T12754 amod immune,response
R8575 T12628 T12627 pobj tumors,to
R8576 T12754 T12751 pobj response,of
R8577 T12755 T12754 prep between,response
R8578 T12629 T12632 mark so,are
R8579 T12756 T12758 det the,+
R8580 T12757 T12758 compound CCR5,+
R8581 T12758 T12755 pobj +,between
R8582 T12630 T12632 mark that,are
R8583 T12759 T12759 ROOT /,/
R8584 T12760 T12761 nummod +,mice
R8585 T12761 T12759 dobj mice,/
R8586 T12762 T12761 cc and,mice
R8587 T12631 T12632 nsubj tumors,are
R8588 T12763 T12765 det the,−
R8589 T12764 T12765 compound CCR5,−
R8590 T12765 T12766 nsubj −,/
R8591 T12766 T12759 conj /,/
R8592 T12767 T12768 nummod −,mice
R8593 T12768 T12766 dobj mice,/
R8594 T12632 T12619 advcl are,reduced
R8595 T12769 T12766 punct ",",/
R8596 T12770 T12766 advcl involving,/
R8597 T12771 T12772 npadvmod tumor,immune
R8598 T12772 T12773 amod immune,tolerance
R8599 T12633 T12632 acomp smaller,are
R8600 T12773 T12770 dobj tolerance,involving
R8601 T12774 T12777 punct ",",connected
R8602 T12775 T12777 aux may,connected
R8603 T12634 T12633 prep in,smaller
R8604 T12776 T12777 auxpass be,connected
R8605 T12777 T12759 conj connected,/
R8606 T12635 T12636 compound control,mice
R8607 T12778 T12777 prep with,connected
R8608 T12779 T12780 det the,inhibition
R8609 T12780 T12778 pobj inhibition,with
R8610 T12636 T12634 pobj mice,in
R8611 T12781 T12780 prep of,inhibition
R8612 T12782 T12783 compound cancer,progression
R8613 T12783 T12781 pobj progression,of
R8614 T12637 T12632 conj [,are
R8615 T12784 T12759 punct .,/
R8616 T12785 T12813 advcl Taken,increased
R8617 T12786 T12785 advmod together,Taken
R8618 T12638 T12639 nummod 9,]
R8619 T12787 T12785 punct ",",Taken
R8620 T12788 T12785 prep in,Taken
R8621 T12789 T12792 det the,experiment
R8622 T12639 T12637 appos ],[
R8623 T12790 T12792 compound cytokine,experiment
R8624 T12791 T12792 compound array,experiment
R8625 T12640 T12592 punct .,suggested
R8626 T12792 T12788 pobj experiment,in
R8627 T12793 T12813 punct ",",increased
R8628 T12641 T12642 det These,data
R8629 T12642 T12643 nsubj data,support
R8630 T12794 T12795 det the,level
R8631 T12643 T12643 ROOT support,support
R8632 T12795 T12813 nsubjpass level,increased
R8633 T12796 T12795 prep of,level
R8634 T12797 T12796 pobj MIP-1α,of
R8635 T12644 T12646 det the,premise
R8636 T12798 T12797 punct (,MIP-1α
R8637 T12799 T12800 nsubj which,has
R8638 T12645 T12646 amod important,premise
R8639 T12800 T12797 relcl has,MIP-1α
R8640 T12646 T12643 dobj premise,support
R8641 T12801 T12803 det a,activity
R8642 T12802 T12803 amod potent,activity
R8643 T12803 T12800 dobj activity,has
R8644 T12804 T12803 prep of,activity
R8645 T12805 T12806 compound T,cell
R8646 T12806 T12804 pobj cell,of
R8647 T12647 T12660 mark that,related
R8648 T12807 T12806 cc and,cell
R8649 T12808 T12809 compound B,cell
R8650 T12648 T12660 nsubjpass inhibition,related
R8651 T12809 T12810 compound cell,migration
R8652 T12810 T12806 conj migration,cell
R8653 T12811 T12797 punct ),MIP-1α
R8654 T12649 T12648 prep of,inhibition
R8655 T12812 T12813 auxpass was,increased
R8656 T12813 T12813 ROOT increased,increased
R8657 T12814 T12813 prep in,increased
R8658 T12650 T12651 compound tumor,growth
R8659 T12815 T12817 det the,−
R8660 T12816 T12817 compound CCR5,−
R8661 T12817 T12814 pobj −,in
R8662 T12651 T12649 pobj growth,of
R8663 T12818 T12813 advcl /,increased
R8664 T12819 T12820 nummod −,mice
R8665 T12820 T12818 dobj mice,/
R8666 T12652 T12648 prep in,inhibition
R8667 T12821 T12818 prep compared,/
R8668 T12822 T12821 prep with,compared
R8669 T12823 T12822 pobj those,with
R8670 T12653 T12657 nummod CCR5,mice
R8671 T12824 T12823 prep in,those
R8672 T12825 T12827 det the,+
R8673 T12826 T12827 compound CCR5,+
R8674 T12654 T12657 nummod −,mice
R8675 T12827 T12828 compound +,/
R8676 T12828 T12818 conj /,/
R8677 T12829 T12830 nummod +,mice
R8678 T12655 T12657 nmod /,mice
R8679 T12830 T12828 dobj mice,/
R8680 T12831 T12828 punct .,/
R8681 T12832 T12841 advmod Thus,play
R8682 T12656 T12657 compound −,mice
R8683 T12833 T12841 punct ",",play
R8684 T12834 T12835 advmod relatively,increased
R8685 T12835 T12839 amod increased,lymphocytes
R8686 T12657 T12652 pobj mice,in
R8687 T12836 T12839 nmod tumor,lymphocytes
R8688 T12837 T12839 amod associated,lymphocytes
R8689 T12838 T12839 compound cytotoxic,lymphocytes
R8690 T12658 T12660 aux could,related
R8691 T12839 T12841 nsubj lymphocytes,play
R8692 T12840 T12841 aux could,play
R8693 T12841 T12841 ROOT play,play
R8694 T12842 T12844 det an,role
R8695 T12843 T12844 amod important,role
R8696 T12844 T12841 dobj role,play
R8697 T12659 T12660 auxpass be,related
R8698 T12845 T12841 prep in,play
R8699 T12846 T12845 pcomp inhibiting,in
R8700 T12847 T12849 det the,growth
R8701 T12660 T12646 acl related,premise
R8702 T12848 T12849 compound tumor,growth
R8703 T12849 T12846 dobj growth,inhibiting
R8704 T12661 T12660 prep with,related
R8705 T12662 T12663 det the,inhibition
R8706 T12850 T12849 prep in,growth
R8707 T12851 T12855 nummod CCR5,mice
R8708 T12852 T12855 nummod −,mice
R8709 T12663 T12661 pobj inhibition,with
R8710 T12853 T12855 nmod /,mice
R8711 T12854 T12855 compound −,mice
R8712 T12855 T12850 pobj mice,in
R8713 T12664 T12663 prep of,inhibition
R8714 T12856 T12841 punct .,play
R8715 T12857 T12861 nsubj Activation,modulate
R8716 T12858 T12857 prep of,Activation
R8717 T12665 T12666 amod immune,escape
R8718 T12859 T12858 pobj NF-κB,of
R8719 T12860 T12861 aux could,modulate
R8720 T12861 T12861 ROOT modulate,modulate
R8721 T12666 T12664 pobj escape,of
R8722 T12862 T12863 amod subcellular,localization
R8723 T12863 T12861 dobj localization,modulate
R8724 T12864 T12863 prep of,localization
R8725 T12667 T12643 punct .,support
R8726 T12865 T12866 compound NK,cells
R8727 T12866 T12864 pobj cells,of
R8728 T12867 T12866 cc and,cells
R8729 T12668 T12674 advmod Similar,found
R8730 T12868 T12869 compound pathogenesis,[
R8731 T12869 T12863 appos [,localization
R8732 T12870 T12871 nummod 49,]
R8733 T12669 T12668 prep to,Similar
R8734 T12871 T12869 appos ],[
R8735 T12872 T12861 punct .,modulate
R8736 T12873 T12877 nsubj Inhibition,prevented
R8737 T12670 T12671 det this,finding
R8738 T12874 T12873 prep of,Inhibition
R8739 T12875 T12876 compound NF-κB,activity
R8740 T12876 T12874 pobj activity,of
R8741 T12671 T12669 pobj finding,to
R8742 T12877 T12877 ROOT prevented,prevented
R8743 T12672 T12674 punct ",",found
R8744 T12878 T12880 compound NK,depletion
R8745 T12879 T12880 compound cell,depletion
R8746 T12880 T12877 dobj depletion,prevented
R8747 T12673 T12674 nsubj we,found
R8748 T12881 T12877 punct ",",prevented
R8749 T12882 T12877 cc and,prevented
R8750 T12883 T12884 advmod thus,increased
R8751 T12674 T12674 ROOT found,found
R8752 T12884 T12877 conj increased,prevented
R8753 T12885 T12886 amod anti-tumor,activity
R8754 T12886 T12884 dobj activity,increased
R8755 T12675 T12679 mark that,/
R8756 T12887 T12884 prep by,increased
R8757 T12888 T12887 pcomp decreasing,by
R8758 T12676 T12678 det the,+
R8759 T12889 T12890 compound IL-6,production
R8760 T12890 T12891 compound production,[
R8761 T12677 T12678 compound CCR5,+
R8762 T12678 T12679 nsubj +,/
R8763 T12679 T12674 ccomp /,found
R8764 T12891 T12888 dobj [,decreasing
R8765 T12680 T12681 nummod +,mice
R8766 T12892 T12893 nummod 50,]
R8767 T12893 T12891 appos ],[
R8768 T12894 T12877 punct .,prevented
R8769 T12681 T12679 dobj mice,/
R8770 T12895 T12906 advmod Thus,associated
R8771 T12896 T12901 punct ",",elevated
R8772 T12682 T12681 acl injected,mice
R8773 T12897 T12899 det the,NF-κB
R8774 T12898 T12899 amod decreased,NF-κB
R8775 T12899 T12901 nsubj NF-κB,elevated
R8776 T12683 T12682 prep with,injected
R8777 T12900 T12899 cc and,NF-κB
R8778 T12901 T12906 csubjpass elevated,associated
R8779 T12902 T12906 nsubjpass IL-1Ra,associated
R8780 T12684 T12685 compound melanoma,cells
R8781 T12903 T12906 aux could,associated
R8782 T12904 T12906 advmod also,associated
R8783 T12905 T12906 auxpass be,associated
R8784 T12685 T12687 nsubj cells,have
R8785 T12906 T12906 ROOT associated,associated
R8786 T12907 T12906 prep in,associated
R8787 T12908 T12909 det the,infiltration
R8788 T12686 T12687 advmod apparently,have
R8789 T12909 T12907 pobj infiltration,in
R8790 T12910 T12909 prep of,infiltration
R8791 T12911 T12912 amod cytotoxic,lymphocytes
R8792 T12912 T12910 pobj lymphocytes,of
R8793 T12913 T12909 prep into,infiltration
R8794 T12914 T12913 pobj tumor,into
R8795 T12687 T12674 ccomp have,found
R8796 T12915 T12906 punct ",",associated
R8797 T12916 T12906 advcl resulting,associated
R8798 T12917 T12916 prep in,resulting
R8799 T12918 T12919 compound tumor,growth
R8800 T12688 T12690 det a,number
R8801 T12919 T12920 compound growth,inhibition
R8802 T12920 T12917 pobj inhibition,in
R8803 T12689 T12690 amod lower,number
R8804 T12921 T12906 punct .,associated
R8805 T12922 T12933 prep In,increased
R8806 T12923 T12922 pobj contrast,In
R8807 T12690 T12687 dobj number,have
R8808 T12924 T12933 punct ",",increased
R8809 T12925 T12933 nsubj IL-23,increased
R8810 T12926 T12925 punct ",",IL-23
R8811 T12691 T12690 prep of,number
R8812 T12927 T12929 det a,growth
R8813 T12928 T12929 compound tumor,growth
R8814 T12929 T12933 nsubj growth,increased
R8815 T12692 T12694 amod cytotoxic,cells
R8816 T12930 T12929 acl promoting,growth
R8817 T12931 T12930 dobj cytokine,promoting
R8818 T12932 T12929 punct ",",growth
R8819 T12693 T12694 compound T,cells
R8820 T12933 T12933 ROOT increased,increased
R8821 T12934 T12933 dobj NF-κB,increased
R8822 T12694 T12691 pobj cells,of
R8823 T12935 T12934 cc and,NF-κB
R8824 T12936 T12938 amod immune,infiltration
R8825 T12937 T12938 compound cell,infiltration
R8826 T12695 T12694 punct (,cells
R8827 T12938 T12934 conj infiltration,NF-κB
R8828 T12939 T12933 prep in,increased
R8829 T12940 T12941 amod oral,tumor
R8830 T12696 T12701 nummod CD8,cells
R8831 T12941 T12939 pobj tumor,in
R8832 T12942 T12944 nmod [,]
R8833 T12988 T12991 det The,incidence
R8834 T12943 T12944 nummod 51,]
R8835 T12944 T12933 npadvmod ],increased
R8836 T12945 T12933 punct .,increased
R8837 T12946 T12947 det These,data
R8838 T12947 T12948 nsubj data,indicate
R8839 T12948 T12948 ROOT indicate,indicate
R8840 T12989 T12991 amod 3-methylcholatrene-induced,incidence
R8841 T12949 T12953 mark that,involved
R8842 T12950 T12953 nsubjpass NF-κB,involved
R8843 T12951 T12953 aux could,involved
R8844 T12952 T12953 auxpass be,involved
R8845 T12953 T12948 ccomp involved,indicate
R8846 T12990 T12991 compound tumor,incidence
R8847 T12954 T12953 prep in,involved
R8848 T12955 T12956 det the,cytokine
R8849 T12956 T12954 pobj cytokine,in
R8850 T12991 T12993 nsubjpass incidence,reduced
R8851 T12992 T12993 auxpass was,reduced
R8852 T12957 T12953 conj mediated,involved
R8853 T12993 T12993 ROOT reduced,reduced
R8854 T12958 T12959 amod anti-tumor,activities
R8855 T12959 T12957 dobj activities,mediated
R8856 T12994 T12993 prep in,reduced
R8857 T12960 T12959 prep of,activities
R8858 T12961 T12962 amod immune,cells
R8859 T12962 T12960 pobj cells,of
R8860 T12995 T12997 amod IL-1α,mice
R8861 T12963 T12948 punct .,indicate
R8862 T12964 T12965 nsubj It,is
R8863 T12965 T12965 ROOT is,is
R8864 T12996 T12997 compound knockout,mice
R8865 T12966 T12965 advmod also,is
R8866 T12967 T12965 acomp noteworthy,is
R8867 T12997 T12994 pobj mice,in
R8868 T12968 T12973 nmod that,growth
R8869 T12969 T12973 amod IL-1Ra,growth
R8870 T12970 T12973 amod inhibited,growth
R8871 T12971 T12972 compound melanoma,tumor
R8872 T12998 T12993 punct ",",reduced
R8873 T12972 T12973 compound tumor,growth
R8874 T12973 T12965 attr growth,is
R8875 T12974 T12973 prep by,growth
R8876 T12999 T12993 cc but,reduced
R8877 T12975 T12974 pcomp increasing,by
R8878 T12976 T12977 det the,number
R8879 T12977 T12975 dobj number,increasing
R8880 T13000 T12993 conj increased,reduced
R8881 T12978 T12977 prep of,number
R8882 T12979 T12981 amod myeloid,cells
R8883 T12980 T12981 compound suppressor,cells
R8884 T13001 T13000 prep in,increased
R8885 T12981 T12978 pobj cells,of
R8886 T12982 T12977 prep in,number
R8887 T12983 T12982 pobj tumor,in
R8888 T13002 T13003 compound IL-1Ra,mice
R8889 T13003 T13001 pobj mice,in
R8890 T12984 T12986 nmod [,]
R8891 T12985 T12986 nummod 25,]
R8892 T12986 T12977 appos ],number
R8893 T12987 T12965 punct .,is
R8894 T13004 T13000 prep with,increased
R8895 T13005 T13006 amod concomitant,maturation
R8896 T13006 T13004 pobj maturation,with
R8897 T13085 T13085 ROOT shown,shown
R8898 T13086 T13087 aux to,be
R8899 T13007 T13006 prep of,maturation
R8900 T13087 T13085 xcomp be,shown
R8901 T13088 T13087 acomp safe,be
R8902 T13089 T13088 prep in,safe
R8903 T13008 T13009 compound NK,cells
R8904 T13090 T13091 amod clinical,trials
R8905 T13091 T13089 pobj trials,in
R8906 T13009 T13007 pobj cells,of
R8907 T13092 T13087 prep for,be
R8908 T13093 T13092 pobj use,for
R8909 T13094 T13093 prep in,use
R8910 T13010 T13009 cc and,cells
R8911 T13095 T13096 amod certain,diseases
R8912 T13096 T13094 pobj diseases,in
R8913 T13097 T13098 amod such,as
R8914 T13011 T13012 amod anti-tumor,immunity
R8915 T13098 T13096 prep as,diseases
R8916 T13099 T13100 compound HIV,[
R8917 T13012 T13006 conj immunity,maturation
R8918 T13100 T13098 pobj [,as
R8919 T13101 T13102 nummod 53,]
R8920 T13102 T13100 conj ],[
R8921 T13013 T13015 nmod [,]
R8922 T13103 T13085 punct .,shown
R8923 T13104 T13107 advmod Thus,believe
R8924 T13105 T13107 punct ",",believe
R8925 T13014 T13015 nummod 52,]
R8926 T13106 T13107 nsubj we,believe
R8927 T13107 T13107 ROOT believe,believe
R8928 T13108 T13109 nsubj CCR5,is
R8929 T13015 T13012 appos ],immunity
R8930 T13109 T13107 ccomp is,believe
R8931 T13110 T13112 det a,target
R8932 T13111 T13112 compound cancer,target
R8933 T13112 T13109 attr target,is
R8934 T13016 T12993 punct .,reduced
R8935 T13113 T13116 dobj that,investigation
R8936 T13114 T13115 nsubj warrants,continued
R8937 T13017 T13018 det These,data
R8938 T13018 T13019 nsubj data,indicate
R8939 T13115 T13116 amod continued,investigation
R8940 T13019 T13019 ROOT indicate,indicate
R8941 T13020 T13032 mark that,be
R8942 T13021 T13022 det the,decrease
R8943 T13116 T13112 appos investigation,target
R8944 T13117 T13107 punct .,believe
R8945 T13118 T13123 prep In,showed
R8946 T13119 T13118 pobj summary,In
R8947 T13120 T13123 punct ",",showed
R8948 T13022 T13032 nsubj decrease,be
R8949 T13121 T13122 det this,study
R8950 T13122 T13123 nsubj study,showed
R8951 T13123 T13123 ROOT showed,showed
R8952 T13124 T13129 mark that,inhibited
R8953 T13023 T13022 prep of,decrease
R8954 T13125 T13126 compound melanoma,cells
R8955 T13126 T13127 compound cells,growth
R8956 T13024 T13023 pobj NF-κB,of
R8957 T13127 T13129 nsubjpass growth,inhibited
R8958 T13128 T13129 auxpass was,inhibited
R8959 T13025 T13022 punct ",",decrease
R8960 T13129 T13123 ccomp inhibited,showed
R8961 T13130 T13129 prep via,inhibited
R8962 T13131 T13130 pobj modulation,via
R8963 T13026 T13022 cc and,decrease
R8964 T13132 T13131 prep of,modulation
R8965 T13133 T13135 compound NF-κB,IL-1Ra
R8966 T13134 T13135 compound /,IL-1Ra
R8967 T13027 T13028 advmod thus,increase
R8968 T13135 T13136 compound IL-1Ra,pathways
R8969 T13136 T13132 pobj pathways,of
R8970 T13137 T13129 prep in,inhibited
R8971 T13028 T13022 conj increase,decrease
R8972 T13138 T13142 nummod CCR5,mice
R8973 T13139 T13142 nummod −,mice
R8974 T13140 T13142 nmod /,mice
R8975 T13029 T13028 prep of,increase
R8976 T13141 T13142 compound −,mice
R8977 T13142 T13137 pobj mice,in
R8978 T13143 T13123 punct .,showed
R8979 T13030 T13029 pobj IL-1Ra,of
R8980 T13031 T13032 aux could,be
R8981 T13032 T13019 ccomp be,indicate
R8982 T13033 T13032 acomp significant,be
R8983 T13034 T13032 prep in,be
R8984 T13035 T13037 compound tumor,inhibition
R8985 T13036 T13037 compound growth,inhibition
R8986 T13037 T13034 pobj inhibition,in
R8987 T13038 T13037 prep of,inhibition
R8988 T13039 T13043 nummod CCR5,mice
R8989 T13040 T13043 nummod −,mice
R8990 T13041 T13043 nmod /,mice
R8991 T13042 T13043 compound −,mice
R8992 T13043 T13038 pobj mice,of
R8993 T13044 T13019 punct .,indicate
R8994 T13045 T13046 poss Our,data
R8995 T13046 T13048 nsubj data,show
R8996 T13047 T13048 advmod thus,show
R8997 T13048 T13048 ROOT show,show
R8998 T13049 T13051 amod significant,implications
R8999 T13050 T13051 amod clinical,implications
R9000 T13051 T13048 dobj implications,show
R9001 T13052 T13051 prep of,implications
R9002 T13053 T13052 pobj CCR5,of
R9003 T13054 T13048 punct ",",show
R9004 T13055 T13057 mark because,is
R9005 T13056 T13057 nsubj CCR5,is
R9006 T13057 T13048 advcl is,show
R9007 T13058 T13060 det a,protein
R9008 T13059 T13060 compound G,protein
R9009 T13060 T13057 attr protein,is
R9010 T13061 T13060 acl coupled,protein
R9011 T13062 T13061 dobj receptor,coupled
R9012 T13063 T13057 cc and,is
R9013 T13064 T13065 nsubj it,is
R9014 T13065 T13057 conj is,is
R9015 T13066 T13065 acomp amenable,is
R9016 T13067 T13068 aux to,use
R9017 T13068 T13066 xcomp use,amenable
R9018 T13069 T13068 prep as,use
R9019 T13070 T13072 det a,molecule
R9020 T13071 T13072 amod small,molecule
R9021 T13072 T13069 pobj molecule,as
R9022 T13073 T13072 prep for,molecule
R9023 T13074 T13075 det the,inhibition
R9024 T13075 T13073 pobj inhibition,for
R9025 T13076 T13075 prep of,inhibition
R9026 T13077 T13076 pobj CCR5,of
R9027 T13078 T13048 punct .,show
R9028 T13079 T13081 amod Several,compounds
R9029 T13080 T13081 amod such,compounds
R9030 T13081 T13085 nsubj compounds,shown
R9031 T13082 T13085 aux have,shown
R9032 T13083 T13085 advmod already,shown
R9033 T13084 T13085 auxpass been,shown
R9068 T13242 T13243 compound Ethics,Statement
R9069 T13243 T13245 compound Statement,experiments
R9070 T13244 T13245 compound All,experiments
R9071 T13245 T13247 nsubjpass experiments,approved
R9072 T13246 T13247 auxpass were,approved
R9073 T13247 T13247 ROOT approved,approved
R9074 T13248 T13247 cc and,approved
R9075 T13249 T13247 conj carried,approved
R9076 T13250 T13249 prt out,carried
R9077 T13251 T13249 prep according,carried
R9078 T13252 T13251 prep to,according
R9079 T13253 T13254 det the,Guide
R9080 T13254 T13252 pobj Guide,to
R9081 T13255 T13254 prep for,Guide
R9082 T13256 T13259 det the,Use
R9083 T13257 T13259 nmod Care,Use
R9084 T13258 T13257 cc and,Care
R9085 T13259 T13255 pobj Use,for
R9086 T13260 T13259 prep of,Use
R9087 T13261 T13260 pobj Animals,of
R9088 T13262 T13265 compound [,Committee
R9089 T13263 T13264 compound Animal,Care
R9090 T13264 T13265 compound Care,Committee
R9091 T13265 T13251 nsubj Committee,according
R9092 T13266 T13265 prep of,Committee
R9093 T13267 T13269 compound Chungbuk,University
R9094 T13268 T13269 compound National,University
R9095 T13269 T13266 pobj University,of
R9096 T13270 T13269 punct ",",University
R9097 T13271 T13273 meta Korea,CBNUA-045-0902-01
R9098 T13272 T13273 punct (,CBNUA-045-0902-01
R9099 T13273 T13275 nmod CBNUA-045-0902-01,]
R9100 T13274 T13275 punct ),]
R9101 T13275 T13265 npadvmod ],Committee
R9102 T13276 T13247 punct .,approved
R9292 T13591 T13591 ROOT Animals,Animals
R9293 T13592 T13595 det The,type
R9294 T13593 T13595 nmod CCR5,type
R9295 T13594 T13595 amod wild,type
R9296 T13595 T13613 nsubjpass type,purchased
R9297 T13596 T13595 punct (,type
R9298 T13597 T13600 meta CCR5,+
R9299 T13598 T13600 nummod +,+
R9300 T13599 T13600 compound /,+
R9301 T13600 T13595 appos +,type
R9302 T13601 T13600 punct ),+
R9303 T13602 T13595 cc and,type
R9304 T13603 T13604 nummod CCR5,knockout
R9305 T13604 T13595 conj knockout,type
R9306 T13605 T13609 punct (,−
R9307 T13606 T13607 nummod CCR5,−
R9308 T13607 T13609 nummod −,−
R9309 T13608 T13609 compound /,−
R9310 T13609 T13604 appos −,knockout
R9311 T13610 T13609 punct ),−
R9312 T13611 T13604 conj mice,knockout
R9313 T13612 T13613 auxpass were,purchased
R9314 T13613 T13613 ROOT purchased,purchased
R9315 T13614 T13613 prep from,purchased
R9316 T13615 T13617 det The,Laboratory
R9317 T13616 T13617 compound Jackson,Laboratory
R9318 T13617 T13614 pobj Laboratory,from
R9319 T13618 T13617 punct (,Laboratory
R9320 T13619 T13620 compound Bar,Harbor
R9321 T13620 T13617 appos Harbor,Laboratory
R9322 T13621 T13620 punct ",",Harbor
R9323 T13622 T13620 appos Maine,Harbor
R9324 T13623 T13624 nummod 04609,USA
R9325 T13624 T13620 appos USA,Harbor
R9326 T13625 T13617 punct ),Laboratory
R9327 T13626 T13613 punct .,purchased
R9328 T13627 T13628 det The,mice
R9329 T13628 T13630 nsubjpass mice,housed
R9330 T13629 T13630 auxpass were,housed
R9331 T13630 T13630 ROOT housed,housed
R9332 T13631 T13630 cc and,housed
R9333 T13632 T13630 conj bred,housed
R9334 T13633 T13632 prep under,bred
R9335 T13634 T13637 amod specific,conditions
R9336 T13635 T13637 amod pathogen,conditions
R9337 T13636 T13637 amod free,conditions
R9338 T13637 T13633 pobj conditions,under
R9339 T13638 T13632 prep at,bred
R9340 T13639 T13643 det the,Center
R9341 T13640 T13643 compound Laboratory,Center
R9342 T13641 T13643 compound Animal,Center
R9343 T13642 T13643 compound Research,Center
R9344 T13643 T13638 pobj Center,at
R9345 T13644 T13643 prep of,Center
R9346 T13645 T13647 compound Chungbuk,University
R9347 T13646 T13647 compound National,University
R9348 T13647 T13644 pobj University,of
R9349 T13648 T13647 punct ",",University
R9350 T13649 T13647 npadvmod Korea,University
R9351 T13650 T13630 punct .,housed
R9352 T13651 T13652 det The,mice
R9353 T13652 T13659 nsubjpass mice,maintained
R9354 T13653 T13652 punct (,mice
R9355 T13654 T13652 appos n,mice
R9356 T13655 T13656 punct =,4/cage
R9357 T13656 T13654 pobj 4/cage,n
R9358 T13657 T13652 punct ),mice
R9359 T13658 T13659 auxpass were,maintained
R9360 T13659 T13659 ROOT maintained,maintained
R9361 T13660 T13659 prep in,maintained
R9362 T13661 T13662 det a,room
R9363 T13662 T13660 pobj room,in
R9364 T13663 T13662 prep with,room
R9365 T13664 T13666 det a,temperature
R9366 T13665 T13666 amod constant,temperature
R9367 T13666 T13663 pobj temperature,with
R9368 T13667 T13666 prep of,temperature
R9369 T13668 T13672 nummod 22,C
R9370 T13669 T13672 compound ±,C
R9371 T13670 T13669 nummod 1,±
R9372 T13671 T13669 nummod °,±
R9373 T13672 T13667 pobj C,of
R9374 T13673 T13672 punct ",",C
R9375 T13674 T13675 amod relative,humidity
R9376 T13675 T13672 appos humidity,C
R9377 T13676 T13675 prep of,humidity
R9378 T13677 T13680 nummod 55,%
R9379 T13678 T13680 nummod ±,%
R9380 T13679 T13680 nummod 10,%
R9381 T13680 T13676 pobj %,of
R9382 T13681 T13672 punct ",",C
R9383 T13682 T13672 cc and,C
R9384 T13683 T13685 amod 12-h,cycle
R9385 T13684 T13685 compound light/dark,cycle
R9386 T13685 T13672 conj cycle,C
R9387 T13686 T13659 punct ",",maintained
R9388 T13687 T13659 cc and,maintained
R9389 T13688 T13659 conj fed,maintained
R9390 T13689 T13691 amod standard,chow
R9391 T13690 T13691 compound rodent,chow
R9392 T13691 T13688 dobj chow,fed
R9393 T13692 T13691 punct (,chow
R9394 T13693 T13691 appos Samyang,chow
R9395 T13694 T13693 punct ",",Samyang
R9396 T13695 T13693 appos Korea,Samyang
R9397 T13696 T13695 punct ),Korea
R9398 T13697 T13688 cc and,fed
R9399 T13698 T13688 conj purified,fed
R9400 T13699 T13659 conj tap,maintained
R9401 T13700 T13701 compound water,ad
R9402 T13701 T13702 compound ad,libitum
R9403 T13702 T13699 dobj libitum,tap
R9404 T13703 T13659 punct .,maintained
R9405 T13704 T13706 det The,+
R9406 T13705 T13706 compound CCR5,+
R9407 T13706 T13707 nsubj +,/
R9408 T13707 T13707 ROOT /,/
R9409 T13708 T13709 nummod +,mice
R9410 T13709 T13707 dobj mice,/
R9411 T13710 T13713 punct (,20
R9412 T13711 T13713 advmod n,20
R9413 T13712 T13713 punct =,20
R9414 T13713 T13709 appos 20,mice
R9415 T13714 T13713 punct ),20
R9416 T13715 T13713 cc and,20
R9417 T13716 T13720 nummod CCR5,mice
R9418 T13717 T13720 nummod −,mice
R9419 T13718 T13720 nmod /,mice
R9420 T13719 T13720 compound −,mice
R9421 T13720 T13709 appos mice,mice
R9422 T13721 T13724 punct (,20
R9423 T13722 T13724 advmod n,20
R9424 T13723 T13724 punct =,20
R9425 T13724 T13720 appos 20,mice
R9426 T13725 T13720 punct ),mice
R9427 T13726 T13709 punct ",",mice
R9428 T13727 T13729 nsubjpass that,used
R9429 T13728 T13729 auxpass were,used
R9430 T13729 T13709 relcl used,mice
R9431 T13730 T13707 punct ",",/
R9432 T13731 T13732 aux had,matched
R9433 T13732 T13707 conj matched,/
R9434 T13733 T13732 dobj ages,matched
R9435 T13734 T13733 punct (,ages
R9436 T13735 T13733 appos 10,ages
R9437 T13736 T13737 nummod 11,weeks
R9438 T13737 T13738 npadvmod weeks,old
R9439 T13738 T13733 amod old,ages
R9440 T13739 T13733 punct ),ages
R9441 T13740 T13733 cc and,ages
R9442 T13741 T13733 conj weights,ages
R9443 T13742 T13733 punct (,ages
R9444 T13743 T13733 appos 16,ages
R9445 T13744 T13745 nummod 19,g
R9446 T13745 T13733 appos g,ages
R9447 T13746 T13733 punct ),ages
R9448 T13747 T13707 punct .,/
R9449 T13748 T13749 compound Control,mice
R9450 T13749 T13753 nsubj mice,were
R9451 T13750 T13749 punct (,mice
R9452 T13751 T13749 appos B6129PF2/J,mice
R9453 T13752 T13749 punct ),mice
R9454 T13753 T13753 ROOT were,were
R9455 T13754 T13756 nummod F2,mice
R9456 T13755 T13756 amod hybrid,mice
R9457 T13756 T13753 attr mice,were
R9458 T13757 T13756 prep from,mice
R9459 T13758 T13759 det the,C57BL/6J-AW-J
R9460 T13759 T13763 nmod C57BL/6J-AW-J,strains
R9461 T13760 T13759 cc and,C57BL/6J-AW-J
R9462 T13761 T13759 conj 129P3/J,C57BL/6J-AW-J
R9463 T13762 T13763 amod parental,strains
R9464 T13763 T13757 pobj strains,from
R9465 T13764 T13753 punct .,were
R9466 T13765 T13766 nummod CCR5,mice
R9467 T13766 T13774 nsubj mice,have
R9468 T13767 T13766 punct (,mice
R9469 T13768 T13766 appos B6,mice
R9470 T13769 T13768 punct ",",B6
R9471 T13770 T13772 amod 129P2-Ccr5tm1Kuz,J
R9472 T13771 T13772 compound /,J
R9473 T13772 T13768 appos J,B6
R9474 T13773 T13766 punct ),mice
R9475 T13774 T13795 ccomp have,129P2-Cmkbr5tm1Kuz
R9476 T13775 T13778 det the,region
R9477 T13776 T13778 amod entire,region
R9478 T13777 T13778 compound coding,region
R9479 T13778 T13774 dobj region,have
R9480 T13779 T13778 prep of,region
R9481 T13780 T13782 det the,gene
R9482 T13781 T13782 compound CCR5,gene
R9483 T13782 T13779 pobj gene,of
R9484 T13783 T13774 conj deleted,have
R9485 T13784 T13783 prep from,deleted
R9486 T13785 T13787 det the,strains
R9487 T13786 T13787 amod parental,strains
R9488 T13787 T13784 pobj strains,from
R9489 T13788 T13783 punct ",",deleted
R9490 T13789 T13783 conj B6,deleted
R9491 T13790 T13789 punct ;,B6
R9492 T13791 T13789 conj 129P2-Ccr5tm1kuz,B6
R9493 T13792 T13791 cc and,129P2-Ccr5tm1kuz
R9494 T13793 T13791 conj B6,129P2-Ccr5tm1kuz
R9495 T13794 T13795 punct ;,129P2-Cmkbr5tm1Kuz
R9496 T13795 T13795 ROOT 129P2-Cmkbr5tm1Kuz,129P2-Cmkbr5tm1Kuz
R9497 T13796 T13795 punct .,129P2-Cmkbr5tm1Kuz
R9612 T13927 T13928 compound Tumor,Inoculation
R9613 T13928 T13934 nmod Inoculation,cells
R9614 T13929 T13928 cc and,Inoculation
R9615 T13930 T13932 compound Tumor,B16
R9616 T13931 T13932 compound Monitoring,B16
R9617 T13932 T13928 conj B16,Inoculation
R9618 T13933 T13934 compound melanoma,cells
R9619 T13934 T13936 nsubjpass cells,injected
R9620 T13935 T13936 auxpass were,injected
R9621 T13936 T13936 ROOT injected,injected
R9622 T13937 T13938 advmod subcutaneously,[
R9623 T13938 T13943 nmod [,cells
R9624 T13939 T13938 nummod 5,[
R9625 T13940 T13943 nummod ×,cells
R9626 T13941 T13943 nummod 105,cells
R9627 T13942 T13943 compound tumor,cells
R9628 T13943 T13936 dobj cells,injected
R9629 T13944 T13936 prep in,injected
R9630 T13945 T13946 nummod 0.1,ml
R9631 T13946 T13947 compound ml,Phosphate
R9632 T13947 T13944 pobj Phosphate,in
R9633 T13948 T13936 advcl buffered,injected
R9634 T13949 T13948 dobj saline,buffered
R9635 T13950 T13951 punct (,PBS
R9636 T13951 T13955 nmod PBS,]
R9637 T13952 T13951 punct ),PBS
R9638 T13953 T13955 advmod /,]
R9639 T13954 T13955 compound animal,]
R9640 T13955 T13948 npadvmod ],buffered
R9641 T13956 T13948 advcl using,buffered
R9642 T13957 T13960 det a,needle
R9643 T13958 T13960 nummod 27,needle
R9644 T13959 T13960 compound G,needle
R9645 T13960 T13956 dobj needle,using
R9646 T13961 T13956 prep into,using
R9647 T13962 T13964 det the,flanks
R9648 T13963 T13964 amod right-lower,flanks
R9649 T13964 T13961 pobj flanks,into
R9650 T13965 T13964 prep of,flanks
R9651 T13966 T13968 det the,mice
R9652 T13967 T13968 compound carrier,mice
R9653 T13968 T13965 pobj mice,of
R9654 T13969 T13971 mark as,described
R9655 T13970 T13971 advmod previously,described
R9656 T13971 T13956 advcl described,using
R9657 T13972 T13974 nmod [,]
R9658 T13973 T13974 nummod 54,]
R9659 T13974 T13971 dobj ],described
R9660 T13975 T13936 punct .,injected
R9661 T13976 T13978 det The,weights
R9662 T13977 T13978 compound body,weights
R9663 T13978 T13986 nsubjpass weights,monitored
R9664 T13979 T13978 cc and,weights
R9665 T13980 T13981 compound tumor,volumes
R9666 T13981 T13978 conj volumes,weights
R9667 T13982 T13978 prep of,weights
R9668 T13983 T13984 det the,animals
R9669 T13984 T13982 pobj animals,of
R9670 T13985 T13986 auxpass were,monitored
R9671 T13986 T13986 ROOT monitored,monitored
R9672 T13987 T13988 advmod twice,weekly
R9673 T13988 T13986 advmod weekly,monitored
R9674 T13989 T13986 punct .,monitored
R9675 T13990 T13992 det The,volumes
R9676 T13991 T13992 compound tumor,volumes
R9677 T13992 T13994 nsubjpass volumes,measured
R9678 T13993 T13994 auxpass were,measured
R9679 T13994 T13994 ROOT measured,measured
R9680 T13995 T13994 prep with,measured
R9681 T13996 T13997 compound Vernier,calipers
R9682 T13997 T13995 pobj calipers,with
R9683 T13998 T13997 cc and,calipers
R9684 T13999 T13997 acl calculated,calipers
R9685 T14000 T13999 advcl using,calculated
R9686 T14001 T14003 det the,formula
R9687 T14002 T14003 amod following,formula
R9688 T14003 T14000 dobj formula,using
R9689 T14004 T13997 punct :,calipers
R9690 T14005 T14008 punct (,B2
R9691 T14006 T14008 det A,B2
R9692 T14007 T14008 compound ×,B2
R9693 T14008 T13997 appos B2,calipers
R9694 T14009 T14008 punct ),B2
R9695 T14010 T14020 nsubj /,is
R9696 T14011 T14010 nummod 2,/
R9697 T14012 T14010 punct ",",/
R9698 T14013 T14015 advmod where,is
R9699 T14014 T14015 nsubj A,is
R9700 T14015 T14010 ccomp is,/
R9701 T14016 T14020 det the,is
R9702 T14017 T14020 amod larger,is
R9703 T14018 T14017 cc and,larger
R9704 T14019 T14020 nsubj B,is
R9705 T14020 T13994 advcl is,measured
R9706 T14021 T14022 det the,smaller
R9707 T14022 T14020 attr smaller,is
R9708 T14023 T14022 prep of,smaller
R9709 T14024 T14026 det the,dimensions
R9710 T14025 T14026 nummod two,dimensions
R9711 T14026 T14023 pobj dimensions,of
R9712 T14027 T14020 punct .,is
R9713 T14028 T14038 prep At,sacrificed
R9714 T14029 T14030 det the,end
R9715 T14030 T14028 pobj end,At
R9716 T14031 T14030 prep of,end
R9717 T14032 T14033 det the,experiment
R9718 T14033 T14031 pobj experiment,of
R9719 T14034 T14038 punct ",",sacrificed
R9720 T14035 T14036 det the,animals
R9721 T14036 T14038 nsubjpass animals,sacrificed
R9722 T14037 T14038 auxpass were,sacrificed
R9723 T14038 T14038 ROOT sacrificed,sacrificed
R9724 T14039 T14038 punct .,sacrificed
R9725 T14040 T14041 det The,tumors
R9726 T14041 T14043 nsubjpass tumors,separated
R9727 T14042 T14043 auxpass were,separated
R9728 T14043 T14043 ROOT separated,separated
R9729 T14044 T14043 prep from,separated
R9730 T14045 T14047 det the,muscles
R9731 T14046 T14047 amod surrounding,muscles
R9732 T14047 T14044 pobj muscles,from
R9733 T14048 T14047 cc and,muscles
R9734 T14049 T14047 conj dermis,muscles
R9735 T14050 T14043 punct .,separated
R9972 T14406 T14409 amod Western,tissues
R9973 T14407 T14409 amod Blotting,tissues
R9974 T14408 T14409 compound Tumor,tissues
R9975 T14409 T14411 nsubjpass tissues,homogenized
R9976 T14410 T14411 auxpass were,homogenized
R9977 T14411 T14411 ROOT homogenized,homogenized
R9978 T14412 T14411 prep with,homogenized
R9979 T14413 T14415 compound protein,solution
R9980 T14414 T14415 compound extraction,solution
R9981 T14415 T14412 pobj solution,with
R9982 T14416 T14428 punct (,lysed
R9983 T14417 T14428 dep PRO-PREPTM,lysed
R9984 T14418 T14417 punct ",",PRO-PREPTM
R9985 T14419 T14420 compound Intron,Biotechnology
R9986 T14420 T14417 conj Biotechnology,PRO-PREPTM
R9987 T14421 T14420 punct ",",Biotechnology
R9988 T14422 T14420 conj Seoul,Biotechnology
R9989 T14423 T14422 punct ",",Seoul
R9990 T14424 T14422 conj Korea,Seoul
R9991 T14425 T14422 punct ),Seoul
R9992 T14426 T14420 punct ",",Biotechnology
R9993 T14427 T14420 cc and,Biotechnology
R9994 T14428 T14411 advcl lysed,homogenized
R9995 T14429 T14428 agent by,lysed
R9996 T14430 T14432 nummod 60,incubation
R9997 T14431 T14432 compound min,incubation
R9998 T14432 T14429 pobj incubation,by
R9999 T14433 T14432 prep on,incubation