bionlp-st-ge-2016-spacy-parsed Home  

PMC:3317373 / 15417-20739 JSONTXT 25 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T8743 14-17 DT denotes The
T8744 18-25 JJ denotes present
T8745 26-31 NN denotes study
T8746 32-44 VBD denotes demonstrated
T8747 45-49 IN denotes that
T8748 50-57 NN denotes scratch
T8749 58-64 NN denotes injury
T8750 65-72 VBD denotes induced
T8751 73-76 DT denotes the
T8752 77-89 NN denotes upregulation
T8753 90-92 IN denotes of
T8754 93-98 NNP denotes NF-κB
T8755 99-102 NNP denotes DNA
T8756 103-110 JJ denotes binding
T8757 111-119 NN denotes activity
T8758 120-123 CC denotes and
T8759 124-138 NN denotes overexpression
T8760 139-141 IN denotes of
T8761 142-147 NNP denotes TNF-α
T8762 147-148 , denotes ,
T8763 149-154 NNP denotes IL-1β
T8764 154-155 , denotes ,
T8765 156-160 NNP denotes IL-6
T8766 160-161 , denotes ,
T8767 162-165 CC denotes and
T8768 166-170 NNP denotes MMP9
T8769 171-173 IN denotes in
T8770 174-182 JJ denotes cultured
T8771 183-193 NNS denotes astrocytes
T8772 193-194 . denotes .
T8773 195-199 RB denotes Also
T8774 200-202 PRP denotes we
T8775 203-211 VBD denotes revealed
T8776 212-216 IN denotes that
T8777 217-224 NN denotes scratch
T8778 225-231 NN denotes injury
T8779 232-239 VBD denotes induced
T8780 240-246 JJR denotes higher
T8781 247-255 NN denotes activity
T8782 256-258 IN denotes of
T8783 259-264 NNP denotes NF-κB
T8784 265-268 CC denotes and
T8785 269-277 JJ denotes enhanced
T8786 278-288 NN denotes expression
T8787 289-291 IN denotes of
T8788 292-307 JJ denotes proinflammatory
T8789 308-317 NNS denotes cytokines
T8790 318-320 IN denotes in
T8791 321-325 JJ denotes Nrf2
T8792 326-334 NN denotes knockout
T8793 335-343 VBD denotes cultured
T8794 344-354 NNS denotes astrocytes
T8795 355-359 IN denotes than
T8796 360-365 DT denotes those
T8797 366-368 IN denotes in
T8798 369-377 NN denotes wildtype
T8799 378-388 NNS denotes astrocytes
T8800 389-392 IN denotes for
T8801 393-396 DT denotes the
T8802 397-402 JJ denotes first
T8803 403-407 NN denotes time
T8804 407-408 . denotes .
T8805 409-411 PRP denotes It
T8806 412-415 VBZ denotes has
T8807 416-420 VBN denotes been
T8808 421-433 VBN denotes demonstrated
T8809 434-438 IN denotes that
T8810 439-444 NNP denotes NF-κB
T8811 445-447 VBZ denotes is
T8812 448-457 VBN denotes activated
T8813 458-460 IN denotes in
T8814 461-466 NN denotes brain
T8815 467-470 CC denotes and
T8816 471-477 JJ denotes spinal
T8817 478-482 NN denotes cord
T8818 483-488 IN denotes after
T8819 489-498 JJ denotes traumatic
T8820 499-505 NN denotes injury
T8821 506-507 NN denotes [
T8822 507-508 CD denotes 2
T8823 508-509 , denotes ,
T8824 510-511 CD denotes 9
T8825 511-512 NN denotes ]
T8826 512-513 . denotes .
T8827 514-516 IN denotes As
T8828 517-518 DT denotes a
T8829 519-529 NN denotes transcript
T8830 530-536 NN denotes factor
T8831 536-537 , denotes ,
T8832 538-543 JJ denotes NF-κB
T8833 544-549 NNS denotes binds
T8834 550-554 IN denotes with
T8835 555-558 NNP denotes DNA
T8836 559-563 IN denotes once
T8837 564-566 PRP denotes it
T8838 567-570 VBD denotes was
T8839 571-580 VBN denotes activated
T8840 581-584 CC denotes and
T8841 585-592 VBZ denotes induces
T8842 593-606 NN denotes transcription
T8843 607-609 IN denotes of
T8844 610-614 NNP denotes MMP9
T8845 615-618 CC denotes and
T8846 619-620 DT denotes a
T8847 621-628 NN denotes battery
T8848 629-631 IN denotes of
T8849 632-647 JJ denotes proinflammatory
T8850 648-657 NNS denotes cytokines
T8851 657-658 , denotes ,
T8852 659-668 VBG denotes including
T8853 669-674 NNP denotes TNF-α
T8854 674-675 , denotes ,
T8855 676-681 NNP denotes IL-1β
T8856 681-682 , denotes ,
T8857 683-686 CC denotes and
T8858 687-691 NNP denotes IL-6
T8859 691-692 , denotes ,
T8860 693-695 IN denotes in
T8861 696-701 NN denotes brain
T8862 702-709 NNS denotes tissues
T8863 710-715 IN denotes after
T8864 716-719 NNP denotes TBI
T8865 720-721 NNP denotes [
T8866 721-722 CD denotes 3
T8867 722-723 , denotes ,
T8868 724-726 CD denotes 10
T8869 726-727 , denotes ,
T8870 728-730 CD denotes 11
T8871 730-731 NN denotes ]
T8872 731-732 . denotes .
T8873 733-736 PRP$ denotes Our
T8874 737-744 NNS denotes results
T8875 745-749 RB denotes also
T8876 750-758 VBD denotes revealed
T8877 759-763 IN denotes that
T8878 764-771 NN denotes scratch
T8879 772-778 NN denotes injury
T8880 779-786 VBD denotes induced
T8881 787-796 NN denotes elevation
T8882 797-799 IN denotes of
T8883 800-805 NNP denotes NF-κB
T8884 806-809 NNP denotes DNA
T8885 810-817 JJ denotes binding
T8886 818-826 NN denotes activity
T8887 826-827 , denotes ,
T8888 828-842 NN denotes overexpression
T8889 843-845 IN denotes of
T8890 846-850 NNP denotes MMP9
T8891 850-851 , denotes ,
T8892 852-855 CC denotes and
T8893 856-871 JJ denotes proinflammatory
T8894 872-881 NNS denotes mediators
T8895 882-891 VBN denotes mentioned
T8896 892-897 IN denotes above
T8897 898-900 IN denotes in
T8898 901-909 JJ denotes cultured
T8899 910-920 NNS denotes astrocytes
T8900 920-921 . denotes .
T8901 922-924 PRP denotes It
T8902 925-928 VBZ denotes has
T8903 929-933 VBN denotes been
T8904 934-946 VBN denotes demonstrated
T8905 947-951 IN denotes that
T8906 952-957 EX denotes there
T8907 958-960 VBZ denotes is
T8908 961-963 DT denotes an
T8909 964-978 JJ denotes autoregulatory
T8910 979-983 NN denotes loop
T8911 984-989 IN denotes among
T8912 990-995 DT denotes these
T8913 996-1011 JJ denotes proinflammatory
T8914 1012-1021 NNS denotes mediators
T8915 1021-1022 . denotes .
T8916 1023-1026 IN denotes For
T8917 1027-1034 NN denotes example
T8918 1034-1035 , denotes ,
T8919 1036-1041 NNP denotes TNF-α
T8920 1042-1045 CC denotes and
T8921 1046-1051 NNP denotes IL-1β
T8922 1052-1055 VBP denotes are
T8923 1056-1062 JJ denotes potent
T8924 1063-1074 NNS denotes stimulators
T8925 1075-1078 IN denotes for
T8926 1079-1083 NNP denotes MMP9
T8927 1084-1086 IN denotes in
T8928 1087-1097 NNS denotes astrocytes
T8929 1098-1099 NNP denotes [
T8930 1099-1101 CD denotes 12
T8931 1101-1102 , denotes ,
T8932 1103-1105 CD denotes 13
T8933 1105-1106 NNP denotes ]
T8934 1106-1107 , denotes ,
T8935 1108-1111 CC denotes and
T8936 1112-1116 NNP denotes IL-6
T8937 1117-1124 VBZ denotes induces
T8938 1125-1139 NN denotes overexpression
T8939 1140-1142 IN denotes of
T8940 1143-1147 NNP denotes MMP9
T8941 1148-1150 IN denotes in
T8942 1151-1156 JJ denotes human
T8943 1157-1162 NN denotes colon
T8944 1163-1172 NN denotes carcinoma
T8945 1173-1178 NNS denotes cells
T8946 1179-1180 NNP denotes [
T8947 1180-1182 CD denotes 14
T8948 1182-1183 NNP denotes ]
T8949 1183-1184 , denotes ,
T8950 1185-1188 CC denotes and
T8951 1189-1194 NNP denotes TNF-α
T8952 1195-1198 CC denotes and
T8953 1199-1204 NNP denotes IL-1β
T8954 1205-1209 RB denotes also
T8955 1210-1213 MD denotes can
T8956 1214-1220 VB denotes induce
T8957 1221-1231 NN denotes activation
T8958 1232-1234 IN denotes of
T8959 1235-1240 NNP denotes NF-κB
T8960 1241-1242 NNP denotes [
T8961 1242-1244 CD denotes 15
T8962 1244-1245 , denotes ,
T8963 1246-1248 CD denotes 16
T8964 1248-1249 NN denotes ]
T8965 1249-1250 . denotes .
T8966 1251-1255 DT denotes This
T8967 1256-1270 JJ denotes autoregulatory
T8968 1271-1275 NN denotes loop
T8969 1276-1285 RB denotes extremely
T8970 1286-1296 VBZ denotes aggravates
T8971 1297-1300 DT denotes the
T8972 1301-1309 JJ denotes damaging
T8973 1310-1316 NN denotes effect
T8974 1317-1319 IN denotes of
T8975 1320-1332 NN denotes inflammation
T8976 1333-1336 CC denotes and
T8977 1337-1344 VBZ denotes induces
T8978 1345-1354 JJ denotes secondary
T8979 1355-1361 NN denotes injury
T8980 1362-1364 TO denotes to
T8981 1365-1370 NN denotes brain
T8982 1370-1371 . denotes .
T8983 1372-1374 PRP denotes It
T8984 1375-1377 VBZ denotes is
T8985 1378-1379 DT denotes a
T8986 1380-1384 JJ denotes good
T8987 1385-1391 NN denotes choice
T8988 1392-1395 IN denotes for
T8989 1396-1405 VBG denotes targeting
T8990 1406-1408 IN denotes on
T8991 1409-1411 DT denotes an
T8992 1412-1420 JJ denotes upstream
T8993 1421-1427 NN denotes factor
T8994 1428-1430 TO denotes to
T8995 1431-1438 VB denotes prevent
T8996 1439-1443 JJ denotes such
T8997 1444-1458 JJ denotes autoregulatory
T8998 1459-1463 NN denotes loop
T8999 1464-1469 IN denotes after
T9000 1470-1473 NNP denotes TBI
T9001 1473-1474 . denotes .
T9002 1475-1483 JJ denotes Nrf2-ARE
T9003 1484-1491 NN denotes pathway
T9004 1492-1495 VBZ denotes has
T9005 1496-1500 VBN denotes been
T9006 1501-1507 VBN denotes proved
T9007 1508-1510 TO denotes to
T9008 1511-1513 VB denotes be
T9009 1514-1517 DT denotes the
T9010 1518-1521 JJ denotes key
T9011 1522-1531 NN denotes regulator
T9012 1532-1534 IN denotes in
T9013 1535-1543 VBG denotes reducing
T9014 1544-1553 JJ denotes oxidative
T9015 1554-1560 NN denotes stress
T9016 1560-1561 , denotes ,
T9017 1562-1574 JJ denotes inflammatory
T9018 1575-1581 NN denotes damage
T9019 1581-1582 , denotes ,
T9020 1583-1586 CC denotes and
T9021 1587-1599 NN denotes accumulation
T9022 1600-1602 IN denotes of
T9023 1603-1608 JJ denotes toxic
T9024 1609-1620 NNS denotes metabolites
T9025 1620-1621 , denotes ,
T9026 1622-1627 WDT denotes which
T9027 1628-1631 VBP denotes are
T9028 1632-1635 DT denotes all
T9029 1636-1644 VBN denotes involved
T9030 1645-1647 IN denotes in
T9031 1648-1651 NNP denotes TBI
T9032 1651-1652 . denotes .
T9033 1653-1656 PRP$ denotes Our
T9034 1657-1665 JJ denotes previous
T9035 1666-1671 NN denotes study
T9036 1672-1675 VBZ denotes has
T9037 1676-1682 VBN denotes proved
T9038 1683-1686 DT denotes the
T9039 1687-1699 NN denotes augmentation
T9040 1700-1702 IN denotes of
T9041 1703-1707 NNP denotes Nrf2
T9042 1708-1710 IN denotes in
T9043 1711-1716 NN denotes brain
T9044 1717-1723 NN denotes tissue
T9045 1724-1729 IN denotes after
T9046 1730-1733 NNP denotes TBI
T9047 1734-1735 NNP denotes [
T9048 1735-1737 CD denotes 17
T9049 1737-1738 NNP denotes ]
T9050 1738-1739 . denotes .
T9051 1740-1748 JJ denotes Enhanced
T9052 1749-1754 NN denotes level
T9053 1755-1757 IN denotes of
T9054 1758-1762 JJ denotes Nrf2
T9055 1763-1772 NNS denotes activates
T9056 1773-1786 NN denotes transcription
T9057 1787-1789 IN denotes of
T9058 1790-1791 DT denotes a
T9059 1792-1797 NN denotes group
T9060 1798-1800 IN denotes of
T9061 1801-1812 JJ denotes antioxidant
T9062 1813-1818 NNS denotes genes
T9063 1818-1819 , denotes ,
T9064 1820-1824 JJ denotes such
T9065 1825-1827 IN denotes as
T9066 1828-1832 NN denotes heme
T9067 1833-1844 JJ denotes oxygenase-1
T9068 1845-1846 -LRB- denotes (
T9069 1846-1850 JJ denotes HO-1
T9070 1850-1851 -RRB- denotes )
T9071 1852-1855 CC denotes and
T9072 1856-1859 NNP denotes NAD
T9073 1860-1861 -LRB- denotes (
T9074 1861-1862 NNP denotes P
T9075 1862-1863 -RRB- denotes )
T9076 1863-1864 NNP denotes H
T9077 1864-1865 : denotes :
T9078 1866-1873 VB denotes quinone
T9079 1874-1890 JJ denotes oxidoreductase-1
T9080 1891-1892 -LRB- denotes (
T9081 1892-1896 CD denotes NQO1
T9082 1896-1897 -RRB- denotes )
T9083 1897-1898 , denotes ,
T9084 1899-1904 WDT denotes which
T9085 1905-1910 MD denotes would
T9086 1911-1923 RB denotes subsequently
T9087 1924-1930 VB denotes reduce
T9088 1931-1934 DT denotes the
T9089 1935-1941 NN denotes damage
T9090 1942-1944 IN denotes in
T9091 1945-1950 NN denotes brain
T9092 1951-1952 NNP denotes [
T9093 1952-1954 CD denotes 18
T9094 1954-1955 NNP denotes ]
T9095 1955-1956 . denotes .
T9096 1957-1967 NNP denotes Postinjury
T9097 1968-1982 NN denotes administration
T9098 1983-1985 IN denotes of
T9099 1986-1989 NNP denotes SFN
T9100 1989-1990 , denotes ,
T9101 1991-1993 DT denotes an
T9102 1994-2001 NN denotes inducer
T9103 2002-2004 IN denotes of
T9104 2005-2009 NNP denotes Nrf2
T9105 2009-2010 , denotes ,
T9106 2011-2024 RB denotes significantly
T9107 2025-2033 VBZ denotes improves
T9108 2034-2041 JJ denotes spatial
T9109 2042-2048 NN denotes memory
T9110 2049-2051 IN denotes of
T9111 2052-2055 NN denotes rat
T9112 2056-2059 CC denotes and
T9113 2060-2069 VBZ denotes decreases
T9114 2070-2073 DT denotes the
T9115 2074-2090 NN denotes immunoreactivity
T9116 2091-2094 IN denotes for
T9117 2095-2111 JJ denotes 4-Hydroxynonenal
T9118 2112-2113 -LRB- denotes (
T9119 2113-2118 JJ denotes 4-HNE
T9120 2118-2119 -RRB- denotes )
T9121 2119-2120 , denotes ,
T9122 2121-2122 DT denotes a
T9123 2123-2129 NN denotes marker
T9124 2130-2132 IN denotes of
T9125 2133-2138 JJ denotes lipid
T9126 2139-2151 NN denotes peroxidation
T9127 2151-2152 , denotes ,
T9128 2153-2155 IN denotes in
T9129 2156-2159 DT denotes the
T9130 2160-2166 NN denotes cortex
T9131 2167-2170 CC denotes and
T9132 2171-2174 DT denotes the
T9133 2175-2178 NNP denotes CA3
T9134 2179-2187 NN denotes subfield
T9135 2188-2190 IN denotes of
T9136 2191-2202 NN denotes hippocampus
T9137 2203-2208 IN denotes after
T9138 2209-2212 NNP denotes TBI
T9139 2213-2214 NNP denotes [
T9140 2214-2216 CD denotes 19
T9141 2216-2217 NNP denotes ]
T9142 2217-2218 . denotes .
T9143 2219-2221 IN denotes On
T9144 2222-2225 DT denotes the
T9145 2226-2231 JJ denotes other
T9146 2232-2236 NN denotes hand
T9147 2236-2237 , denotes ,
T9148 2238-2252 JJ denotes Nrf2-deficient
T9149 2253-2257 NNS denotes mice
T9150 2258-2264 VBP denotes appear
T9151 2265-2269 JJR denotes more
T9152 2270-2281 JJ denotes susceptible
T9153 2282-2284 TO denotes to
T9154 2285-2288 NNP denotes TBI
T9155 2288-2289 . denotes .
T9156 2290-2299 NN denotes Depletion
T9157 2300-2302 IN denotes of
T9158 2303-2307 JJ denotes Nrf2
T9159 2308-2315 VBZ denotes induces
T9160 2316-2322 JJR denotes higher
T9161 2323-2333 NN denotes expression
T9162 2334-2336 IN denotes of
T9163 2337-2352 JJ denotes proinflammatory
T9164 2353-2362 NNS denotes mediators
T9165 2363-2365 IN denotes in
T9166 2366-2371 NN denotes brain
T9167 2372-2377 IN denotes after
T9168 2378-2381 NNP denotes TBI
T9169 2382-2383 NNP denotes [
T9170 2383-2385 CD denotes 20
T9171 2385-2386 NNP denotes ]
T9172 2386-2387 . denotes .
T9173 2388-2392 RB denotes Here
T9174 2392-2393 , denotes ,
T9175 2394-2397 PRP$ denotes our
T9176 2398-2405 NNS denotes results
T9177 2406-2414 VBD denotes revealed
T9178 2415-2419 IN denotes that
T9179 2420-2434 NN denotes overexpression
T9180 2435-2437 IN denotes of
T9181 2438-2443 NNP denotes TNF-α
T9182 2443-2444 , denotes ,
T9183 2445-2450 NNP denotes IL-1β
T9184 2450-2451 , denotes ,
T9185 2452-2456 NNP denotes IL-6
T9186 2456-2457 , denotes ,
T9187 2458-2461 CC denotes and
T9188 2462-2466 NNP denotes MMP9
T9189 2467-2472 IN denotes after
T9190 2473-2480 NN denotes scratch
T9191 2481-2487 NN denotes injury
T9192 2488-2491 VBD denotes was
T9193 2492-2496 RBR denotes more
T9194 2497-2507 VBN denotes aggravated
T9195 2508-2510 IN denotes in
T9196 2511-2519 JJ denotes cultured
T9197 2520-2524 JJ denotes Nrf2
T9198 2525-2533 NN denotes knockout
T9199 2534-2544 NNS denotes astrocytes
T9200 2545-2549 IN denotes than
T9201 2550-2552 IN denotes in
T9202 2553-2561 NN denotes wildtype
T9203 2562-2573 NNS denotes astrocyetes
T9204 2574-2577 IN denotes for
T9205 2578-2581 DT denotes the
T9206 2582-2587 JJ denotes first
T9207 2588-2592 NN denotes time
T9208 2592-2593 , denotes ,
T9209 2594-2597 CC denotes and
T9210 2598-2612 NN denotes overexpression
T9211 2613-2615 IN denotes of
T9212 2616-2621 DT denotes these
T9213 2622-2637 JJ denotes proinflammatory
T9214 2638-2647 NNS denotes mediators
T9215 2648-2651 VBD denotes led
T9216 2652-2654 TO denotes to
T9217 2655-2659 JJR denotes more
T9218 2660-2670 NNS denotes astrocytes
T9219 2671-2677 NNS denotes deaths
T9220 2677-2678 . denotes .
T9221 2679-2683 NNP denotes Data
T9222 2684-2692 VBD denotes obtained
T9223 2693-2697 IN denotes from
T9224 2698-2704 JJ denotes animal
T9225 2705-2712 NNS denotes studies
T9226 2713-2720 VBP denotes suggest
T9227 2721-2724 DT denotes the
T9228 2725-2736 NN denotes possibility
T9229 2737-2741 WDT denotes that
T9230 2742-2753 JJ denotes antioxidant
T9231 2754-2760 NN denotes effect
T9232 2761-2763 IN denotes of
T9233 2764-2768 NNP denotes Nrf2
T9234 2769-2772 MD denotes may
T9235 2773-2775 VB denotes be
T9236 2776-2784 VBN denotes achieved
T9237 2785-2787 IN denotes by
T9238 2788-2799 NN denotes suppression
T9239 2800-2802 IN denotes of
T9240 2803-2818 JJ denotes proinflammatory
T9241 2819-2827 NNS denotes pathways
T9242 2828-2833 WDT denotes which
T9243 2834-2837 VBP denotes are
T9244 2838-2846 VBN denotes mediated
T9245 2847-2849 IN denotes by
T9246 2850-2855 JJ denotes NF-κB
T9247 2856-2865 VBG denotes signaling
T9248 2865-2866 . denotes .
T9249 2867-2881 NNP denotes Administration
T9250 2882-2884 IN denotes of
T9251 2885-2888 NNP denotes SFN
T9252 2889-2891 VBZ denotes is
T9253 2892-2897 VBN denotes found
T9254 2898-2900 TO denotes to
T9255 2901-2903 VB denotes be
T9256 2904-2908 JJ denotes able
T9257 2909-2911 TO denotes to
T9258 2912-2919 VB denotes inhibit
T9259 2920-2925 NNP denotes IKK/I
T9260 2925-2927 NNP denotes κB
T9261 2928-2943 NN denotes phosphorylation
T9262 2944-2947 CC denotes and
T9263 2948-2951 CD denotes p65
T9264 2952-2957 JJ denotes NF-κB
T9265 2958-2965 NN denotes subunit
T9266 2966-2973 JJ denotes nuclear
T9267 2974-2987 NN denotes translocation
T9268 2987-2988 , denotes ,
T9269 2989-3001 RB denotes consequently
T9270 3002-3013 VBG denotes alleviating
T9271 3014-3019 JJ denotes NF-κB
T9272 3020-3029 VBG denotes signaling
T9273 3030-3031 NNP denotes [
T9274 3031-3033 CD denotes 21
T9275 3033-3034 NNP denotes ]
T9276 3034-3035 . denotes .
T9277 3036-3039 CC denotes And
T9278 3040-3045 JJ denotes NF-κB
T9279 3046-3056 NN denotes activation
T9280 3057-3064 VBN denotes induced
T9281 3065-3067 IN denotes by
T9282 3068-3086 NN denotes lipopolysaccharide
T9283 3087-3088 -LRB- denotes (
T9284 3088-3091 NNP denotes LPS
T9285 3091-3092 -RRB- denotes )
T9286 3093-3098 MD denotes could
T9287 3099-3101 VB denotes be
T9288 3102-3112 VBN denotes attenuated
T9289 3113-3115 IN denotes by
T9290 3116-3123 JJ denotes diverse
T9291 3124-3128 JJ denotes Nrf2
T9292 3129-3139 NNS denotes activators
T9293 3139-3140 , denotes ,
T9294 3141-3145 JJ denotes such
T9295 3146-3148 IN denotes as
T9296 3149-3152 NNP denotes SFN
T9297 3153-3156 CC denotes and
T9298 3157-3165 NN denotes curcumin
T9299 3166-3167 -LRB- denotes (
T9300 3167-3170 NNP denotes CUR
T9301 3170-3171 -RRB- denotes )
T9302 3172-3173 NNP denotes [
T9303 3173-3175 CD denotes 22
T9304 3175-3176 NNP denotes ]
T9305 3176-3177 . denotes .
T9306 3178-3189 RB denotes Furthermore
T9307 3189-3190 , denotes ,
T9308 3191-3194 PRP$ denotes our
T9309 3195-3203 JJ denotes previous
T9310 3204-3211 NNS denotes studies
T9311 3212-3220 VBP denotes indicate
T9312 3221-3225 IN denotes that
T9313 3226-3235 NN denotes depletion
T9314 3236-3238 IN denotes of
T9315 3239-3243 JJ denotes Nrf2
T9316 3244-3251 VBZ denotes induces
T9317 3252-3264 NN denotes augmentation
T9318 3265-3267 IN denotes of
T9319 3268-3273 JJ denotes NF-κB
T9320 3274-3282 NN denotes activity
T9321 3283-3286 CC denotes and
T9322 3287-3299 JJ denotes inflammatory
T9323 3300-3308 NN denotes response
T9324 3309-3311 IN denotes in
T9325 3312-3316 NN denotes lung
T9326 3316-3317 , denotes ,
T9327 3318-3323 NN denotes brain
T9328 3323-3324 , denotes ,
T9329 3325-3328 CC denotes and
T9330 3329-3338 JJ denotes intestine
T9331 3339-3344 IN denotes after
T9332 3345-3348 NNP denotes TBI
T9333 3349-3350 NNP denotes [
T9334 3350-3351 CD denotes 4
T9335 3351-3352 , denotes ,
T9336 3353-3354 CD denotes 5
T9337 3354-3355 , denotes ,
T9338 3356-3358 CD denotes 23
T9339 3358-3359 NNP denotes ]
T9340 3359-3360 . denotes .
T9341 3361-3368 NNS denotes Results
T9342 3369-3373 IN denotes from
T9343 3374-3378 DT denotes this
T9344 3379-3384 NN denotes study
T9345 3385-3392 JJ denotes further
T9346 3393-3402 VBD denotes confirmed
T9347 3403-3407 JJ denotes such
T9348 3408-3420 NN denotes relationship
T9349 3421-3428 VBD denotes existed
T9350 3429-3431 IN denotes in
T9351 3432-3440 JJ denotes cultured
T9352 3441-3451 NNS denotes astrocytes
T9353 3452-3457 IN denotes after
T9354 3458-3465 NN denotes scratch
T9355 3466-3472 NN denotes injury
T9356 3472-3473 . denotes .
T9357 3474-3482 VBN denotes Enhanced
T9358 3483-3493 NN denotes activation
T9359 3494-3496 IN denotes of
T9360 3497-3502 NNP denotes NF-κB
T9361 3503-3505 VBZ denotes is
T9362 3506-3510 RB denotes also
T9363 3511-3521 VBN denotes discovered
T9364 3522-3524 IN denotes in
T9365 3525-3529 NN denotes lung
T9366 3529-3530 , denotes ,
T9367 3531-3542 NNS denotes macrophages
T9368 3542-3543 , denotes ,
T9369 3544-3547 CC denotes and
T9370 3548-3553 NN denotes mouse
T9371 3554-3563 JJ denotes embryonic
T9372 3564-3575 NNS denotes fibroblasts
T9373 3576-3578 IN denotes of
T9374 3579-3593 JJ denotes Nrf2-deficient
T9375 3594-3598 NNS denotes mice
T9376 3599-3604 IN denotes after
T9377 3605-3617 JJ denotes experimental
T9378 3618-3624 NN denotes sepsis
T9379 3625-3626 NNP denotes [
T9380 3626-3628 CD denotes 24
T9381 3628-3629 NNP denotes ]
T9382 3629-3630 . denotes .
T9383 3631-3644 RB denotes Interestingly
T9384 3644-3645 , denotes ,
T9385 3646-3648 PRP denotes it
T9386 3649-3651 VBZ denotes is
T9387 3652-3660 VBN denotes reported
T9388 3661-3665 IN denotes that
T9389 3666-3671 NNP denotes NF-κB
T9390 3672-3675 MD denotes can
T9391 3676-3683 VB denotes inhibit
T9392 3684-3688 NNP denotes Nrf2
T9393 3689-3691 IN denotes at
T9394 3692-3707 JJ denotes transcriptional
T9395 3708-3713 NN denotes level
T9396 3713-3714 . denotes .
T9397 3715-3720 NNP denotes NF-κB
T9398 3721-3724 CD denotes p65
T9399 3725-3732 NN denotes subunit
T9400 3733-3742 VBD denotes repressed
T9401 3743-3746 DT denotes the
T9402 3747-3755 JJ denotes Nrf2-ARE
T9403 3756-3763 NN denotes pathway
T9404 3764-3766 IN denotes at
T9405 3767-3782 JJ denotes transcriptional
T9406 3783-3788 NN denotes level
T9407 3789-3791 IN denotes by
T9408 3792-3803 JJ denotes competitive
T9409 3804-3815 NN denotes interaction
T9410 3816-3820 IN denotes with
T9411 3821-3824 DT denotes the
T9412 3825-3832 NNP denotes CH1-KIX
T9413 3833-3839 NN denotes domain
T9414 3840-3842 IN denotes of
T9415 3843-3846 NNP denotes CBP
T9416 3847-3849 CC denotes or
T9417 3850-3855 JJ denotes local
T9418 3856-3863 NN denotes histone
T9419 3864-3879 NN denotes hypoacetylation
T9420 3880-3881 NNP denotes [
T9421 3881-3883 CD denotes 25
T9422 3883-3884 NNP denotes ]
T9423 3884-3885 . denotes .
T9424 3886-3889 PDT denotes All
T9425 3890-3895 DT denotes these
T9426 3896-3904 NNS denotes findings
T9427 3905-3913 VBP denotes indicate
T9428 3914-3917 DT denotes the
T9429 3918-3927 JJ denotes potential
T9430 3928-3938 VBP denotes complicate
T9431 3939-3948 NN denotes crosstalk
T9432 3949-3956 IN denotes between
T9433 3957-3962 NNP denotes NF-κB
T9434 3963-3966 CC denotes and
T9435 3967-3971 NNP denotes Nrf2
T9436 3971-3972 , denotes ,
T9437 3973-3978 WDT denotes which
T9438 3979-3982 MD denotes may
T9439 3983-3985 VB denotes be
T9440 3986-3995 VBN denotes regulated
T9441 3996-3998 IN denotes by
T9442 3999-4002 DT denotes the
T9443 4003-4011 JJ denotes upstream
T9444 4012-4029 JJ denotes mitogen-activated
T9445 4030-4037 NN denotes protein
T9446 4038-4044 NN denotes kinase
T9447 4045-4046 -LRB- denotes (
T9448 4046-4051 NNS denotes MAPKs
T9449 4051-4052 -RRB- denotes )
T9450 4053-4060 VBP denotes pathway
T9451 4061-4062 NNP denotes [
T9452 4062-4064 CD denotes 26
T9453 4064-4065 NNP denotes ]
T9454 4065-4066 . denotes .
T9455 4067-4069 PRP denotes It
T9456 4070-4073 VBZ denotes has
T9457 4074-4078 VBN denotes been
T9458 4079-4088 VBN denotes confirmed
T9459 4089-4093 IN denotes that
T9460 4094-4098 NNP denotes Nrf2
T9461 4099-4101 VBZ denotes is
T9462 4102-4108 RB denotes mainly
T9463 4109-4117 VBN denotes detected
T9464 4118-4120 IN denotes in
T9465 4121-4128 NN denotes nucleus
T9466 4129-4131 IN denotes of
T9467 4132-4142 NNS denotes astrocytes
T9468 4143-4148 IN denotes after
T9469 4149-4152 NNP denotes TBI
T9470 4153-4154 NNP denotes [
T9471 4154-4156 CD denotes 18
T9472 4156-4157 NNP denotes ]
T9473 4157-4158 . denotes .
T9474 4159-4161 IN denotes In
T9475 4162-4166 NN denotes view
T9476 4167-4169 IN denotes of
T9477 4170-4173 DT denotes the
T9478 4174-4178 NN denotes fact
T9479 4179-4183 IN denotes that
T9480 4184-4188 NNP denotes Nrf2
T9481 4189-4191 VBZ denotes is
T9482 4192-4193 DT denotes a
T9483 4194-4207 NN denotes transcription
T9484 4208-4214 NN denotes factor
T9485 4215-4220 WDT denotes which
T9486 4221-4227 MD denotes should
T9487 4228-4232 VB denotes take
T9488 4233-4241 NN denotes function
T9489 4242-4248 RB denotes mainly
T9490 4249-4251 IN denotes in
T9491 4252-4259 NN denotes nucleus
T9492 4259-4260 , denotes ,
T9493 4261-4263 PRP denotes it
T9494 4264-4267 MD denotes can
T9495 4268-4270 VB denotes be
T9496 4271-4279 VBN denotes reasoned
T9497 4280-4284 IN denotes that
T9498 4285-4295 NNS denotes astrocytes
T9499 4296-4299 MD denotes may
T9500 4300-4302 VB denotes be
T9501 4303-4306 CD denotes one
T9502 4307-4311 NN denotes kind
T9503 4312-4314 IN denotes of
T9504 4315-4325 NN denotes respondent
T9505 4326-4331 NNS denotes cells
T9506 4332-4334 IN denotes in
T9507 4335-4345 NN denotes activation
T9508 4346-4348 IN denotes of
T9509 4349-4357 JJ denotes Nrf2-ARE
T9510 4358-4365 NN denotes pathway
T9511 4366-4371 IN denotes after
T9512 4372-4375 NNP denotes TBI
T9513 4375-4376 . denotes .
T9514 4377-4385 JJ denotes Previous
T9515 4386-4391 NN denotes study
T9516 4392-4402 VBD denotes identified
T9517 4403-4406 DT denotes the
T9518 4407-4417 NN denotes expression
T9519 4418-4420 IN denotes of
T9520 4421-4426 NNP denotes TNF-α
T9521 4426-4427 , denotes ,
T9522 4428-4433 NNP denotes IL-1β
T9523 4433-4434 , denotes ,
T9524 4435-4438 CC denotes and
T9525 4439-4443 NNP denotes IL-6
T9526 4444-4446 IN denotes in
T9527 4447-4455 JJ denotes cultured
T9528 4456-4466 NNS denotes astrocytes
T9529 4467-4472 IN denotes after
T9530 4473-4482 NN denotes treatment
T9531 4483-4487 IN denotes with
T9532 4488-4491 NNP denotes LPS
T9533 4492-4494 CC denotes or
T9534 4495-4508 VBN denotes oxyhemoglobin
T9535 4509-4510 NNP denotes [
T9536 4510-4512 CD denotes 27
T9537 4512-4513 , denotes ,
T9538 4514-4516 CD denotes 28
T9539 4516-4517 NN denotes ]
T9540 4517-4518 . denotes .
T9541 4519-4526 DT denotes Another
T9542 4527-4532 NN denotes study
T9543 4533-4541 VBD denotes revealed
T9544 4542-4546 IN denotes that
T9545 4547-4552 IN denotes after
T9546 4553-4559 JJ denotes middle
T9547 4560-4568 JJ denotes cerebral
T9548 4569-4575 NN denotes artery
T9549 4576-4585 NN denotes occlusion
T9550 4585-4586 , denotes ,
T9551 4587-4600 JJ denotes MMP9-positive
T9552 4601-4611 NNS denotes astrocytes
T9553 4612-4616 VBD denotes were
T9554 4617-4625 VBN denotes observed
T9555 4626-4628 IN denotes in
T9556 4629-4634 NN denotes brain
T9557 4635-4642 NNS denotes tissues
T9558 4643-4645 IN denotes by
T9559 4646-4666 NN denotes immunohistochemistry
T9560 4667-4668 NNP denotes [
T9561 4668-4670 CD denotes 29
T9562 4670-4671 NNP denotes ]
T9563 4671-4672 . denotes .
T9564 4673-4678 DT denotes Those
T9565 4679-4686 NNS denotes results
T9566 4687-4695 VBP denotes indicate
T9567 4696-4699 DT denotes the
T9568 4700-4704 NN denotes role
T9569 4705-4707 IN denotes of
T9570 4708-4718 NNS denotes astrocytes
T9571 4719-4721 IN denotes in
T9572 4722-4734 JJ denotes inflammatory
T9573 4735-4742 NN denotes process
T9574 4743-4748 IN denotes after
T9575 4749-4754 NN denotes brain
T9576 4755-4761 NN denotes injury
T9577 4761-4762 . denotes .
T9578 4763-4766 CC denotes But
T9579 4767-4771 IN denotes till
T9580 4772-4775 RB denotes now
T9581 4775-4776 , denotes ,
T9582 4777-4782 EX denotes there
T9583 4783-4785 VBZ denotes is
T9584 4786-4788 DT denotes no
T9585 4789-4794 NN denotes study
T9586 4795-4802 VBD denotes focused
T9587 4803-4805 IN denotes on
T9588 4806-4809 DT denotes the
T9589 4810-4822 NN denotes relationship
T9590 4823-4828 IN denotes among
T9591 4829-4839 NNS denotes astrocytes
T9592 4839-4840 , denotes ,
T9593 4841-4845 NNP denotes Nrf2
T9594 4845-4846 , denotes ,
T9595 4847-4850 CC denotes and
T9596 4851-4866 JJ denotes proinflammatory
T9597 4867-4876 NNS denotes mediators
T9598 4877-4882 IN denotes after
T9599 4883-4886 NNP denotes TBI
T9600 4886-4887 . denotes .
T9601 4888-4891 PRP$ denotes Our
T9602 4892-4899 NNS denotes results
T9603 4900-4912 VBD denotes demonstrated
T9604 4913-4916 DT denotes the
T9605 4917-4928 JJ denotes upregulated
T9606 4929-4939 NN denotes expression
T9607 4940-4942 IN denotes of
T9608 4943-4948 NNP denotes TNF-α
T9609 4948-4949 , denotes ,
T9610 4950-4955 NNP denotes IL-1β
T9611 4955-4956 , denotes ,
T9612 4957-4961 NNP denotes IL-6
T9613 4961-4962 , denotes ,
T9614 4963-4966 CC denotes and
T9615 4967-4971 NNP denotes MMP9
T9616 4972-4974 IN denotes in
T9617 4975-4979 NNP denotes Nrf2
T9618 4980-4988 NN denotes knockout
T9619 4989-4999 NNS denotes astrocytes
T9620 5000-5005 IN denotes after
T9621 5006-5013 NN denotes scratch
T9622 5014-5020 NN denotes injury
T9623 5021-5024 IN denotes for
T9624 5025-5028 DT denotes the
T9625 5029-5034 JJ denotes first
T9626 5035-5039 NN denotes time
T9627 5039-5040 . denotes .
T9628 5041-5043 IN denotes In
T9629 5044-5054 NN denotes conclusion
T9630 5054-5055 , denotes ,
T9631 5056-5065 NN denotes depletion
T9632 5066-5068 IN denotes of
T9633 5069-5073 JJ denotes Nrf2
T9634 5074-5081 VBD denotes induced
T9635 5082-5085 DT denotes the
T9636 5086-5096 NN denotes activation
T9637 5097-5099 IN denotes of
T9638 5100-5105 NNP denotes NF-κB
T9639 5106-5109 CC denotes and
T9640 5110-5113 DT denotes the
T9641 5114-5124 NN denotes expression
T9642 5125-5127 IN denotes of
T9643 5128-5133 NNP denotes TNF-α
T9644 5133-5134 , denotes ,
T9645 5135-5140 NNP denotes IL-1β
T9646 5140-5141 , denotes ,
T9647 5142-5146 NNP denotes IL-6
T9648 5146-5147 , denotes ,
T9649 5148-5151 CC denotes and
T9650 5152-5156 NNP denotes MMP9
T9651 5157-5166 VBG denotes resulting
T9652 5167-5169 IN denotes in
T9653 5170-5174 JJR denotes more
T9654 5175-5179 NN denotes cell
T9655 5180-5186 NNS denotes deaths
T9656 5187-5189 IN denotes in
T9657 5190-5200 NNS denotes astrocytes
T9658 5201-5206 IN denotes after
T9659 5207-5214 NN denotes scratch
T9660 5215-5221 NN denotes injury
T9661 5221-5222 . denotes .
T9662 5223-5228 DT denotes These
T9663 5229-5236 NNS denotes results
T9664 5237-5244 VBP denotes suggest
T9665 5245-5249 IN denotes that
T9666 5250-5254 NNP denotes Nrf2
T9667 5255-5258 MD denotes may
T9668 5259-5261 VB denotes be
T9669 5262-5264 DT denotes an
T9670 5265-5274 JJ denotes important
T9671 5275-5281 NN denotes target
T9672 5282-5285 IN denotes for
T9673 5286-5303 JJ denotes anti-inflammatory
T9674 5304-5311 NN denotes therapy
T9675 5312-5317 IN denotes after
T9676 5318-5321 NNP denotes TBI
T9677 5321-5322 . denotes .
R7071 T8743 T8745 det The,study
R7072 T8744 T8745 amod present,study
R7073 T8745 T8746 nsubj study,demonstrated
R7074 T8746 T8746 ROOT demonstrated,demonstrated
R7075 T8747 T8750 mark that,induced
R7076 T8748 T8749 compound scratch,injury
R7077 T8749 T8750 nsubj injury,induced
R7078 T8750 T8746 ccomp induced,demonstrated
R7079 T8751 T8752 det the,upregulation
R7080 T8752 T8750 dobj upregulation,induced
R7081 T8753 T8752 prep of,upregulation
R7082 T8754 T8755 compound NF-κB,DNA
R7083 T8755 T8753 pobj DNA,of
R7084 T8756 T8757 amod binding,activity
R7085 T8757 T8753 pobj activity,of
R7086 T8758 T8757 cc and,activity
R7087 T8759 T8757 conj overexpression,activity
R7088 T8760 T8759 prep of,overexpression
R7089 T8761 T8760 pobj TNF-α,of
R7090 T8762 T8761 punct ",",TNF-α
R7091 T8763 T8761 conj IL-1β,TNF-α
R7092 T8764 T8763 punct ",",IL-1β
R7093 T8765 T8763 conj IL-6,IL-1β
R7094 T8766 T8765 punct ",",IL-6
R7095 T8767 T8765 cc and,IL-6
R7096 T8768 T8765 conj MMP9,IL-6
R7097 T8769 T8752 prep in,upregulation
R7098 T8770 T8771 amod cultured,astrocytes
R7099 T8771 T8769 pobj astrocytes,in
R7100 T8772 T8746 punct .,demonstrated
R7101 T8773 T8775 advmod Also,revealed
R7102 T8774 T8775 nsubj we,revealed
R7103 T8775 T8775 ROOT revealed,revealed
R7104 T8776 T8779 mark that,induced
R7105 T8777 T8778 compound scratch,injury
R7106 T8778 T8779 nsubj injury,induced
R7107 T8779 T8775 ccomp induced,revealed
R7108 T8780 T8781 amod higher,activity
R7109 T8781 T8779 dobj activity,induced
R7110 T8782 T8781 prep of,activity
R7111 T8783 T8782 pobj NF-κB,of
R7112 T8784 T8781 cc and,activity
R7113 T8785 T8786 amod enhanced,expression
R7114 T8786 T8781 conj expression,activity
R7115 T8787 T8786 prep of,expression
R7116 T8788 T8789 amod proinflammatory,cytokines
R7117 T8789 T8787 pobj cytokines,of
R7118 T8790 T8789 prep in,cytokines
R7119 T8791 T8792 amod Nrf2,knockout
R7120 T8792 T8790 pobj knockout,in
R7121 T8793 T8779 conj cultured,induced
R7122 T8794 T8793 dobj astrocytes,cultured
R7123 T8795 T8794 prep than,astrocytes
R7124 T8796 T8795 pobj those,than
R7125 T8797 T8796 prep in,those
R7126 T8798 T8799 compound wildtype,astrocytes
R7127 T8799 T8797 pobj astrocytes,in
R7128 T8800 T8793 prep for,cultured
R7129 T8801 T8803 det the,time
R7130 T8802 T8803 amod first,time
R7131 T8803 T8800 pobj time,for
R7132 T8804 T8775 punct .,revealed
R7133 T8805 T8808 nsubjpass It,demonstrated
R7134 T8806 T8808 aux has,demonstrated
R7135 T8807 T8808 auxpass been,demonstrated
R7136 T8808 T8808 ROOT demonstrated,demonstrated
R7137 T8809 T8812 mark that,activated
R7138 T8810 T8812 nsubjpass NF-κB,activated
R7139 T8811 T8812 auxpass is,activated
R7140 T8812 T8808 ccomp activated,demonstrated
R7141 T8813 T8812 prep in,activated
R7142 T8814 T8813 pobj brain,in
R7143 T8815 T8814 cc and,brain
R7144 T8816 T8817 amod spinal,cord
R7145 T8817 T8814 conj cord,brain
R7146 T8818 T8812 prep after,activated
R7147 T8819 T8821 amod traumatic,[
R7148 T8820 T8821 compound injury,[
R7149 T8821 T8818 pobj [,after
R7150 T8822 T8821 nummod 2,[
R7151 T8823 T8821 punct ",",[
R7152 T8824 T8825 nummod 9,]
R7153 T8825 T8821 appos ],[
R7154 T8826 T8808 punct .,demonstrated
R7155 T8827 T8839 prep As,activated
R7156 T8828 T8830 det a,factor
R7157 T8829 T8830 compound transcript,factor
R7158 T8830 T8827 pobj factor,As
R7159 T8831 T8839 punct ",",activated
R7160 T8832 T8833 amod NF-κB,binds
R7161 T8833 T8839 nsubjpass binds,activated
R7162 T8834 T8833 prep with,binds
R7163 T8835 T8834 pobj DNA,with
R7164 T8836 T8839 mark once,activated
R7165 T8837 T8839 nsubjpass it,activated
R7166 T8838 T8839 auxpass was,activated
R7167 T8839 T8839 ROOT activated,activated
R7168 T8840 T8839 cc and,activated
R7169 T8841 T8839 conj induces,activated
R7170 T8842 T8841 dobj transcription,induces
R7171 T8843 T8842 prep of,transcription
R7172 T8844 T8843 pobj MMP9,of
R7173 T8845 T8842 cc and,transcription
R7174 T8846 T8847 det a,battery
R7175 T8847 T8842 conj battery,transcription
R7176 T8848 T8847 prep of,battery
R7177 T8849 T8850 amod proinflammatory,cytokines
R7178 T8850 T8848 pobj cytokines,of
R7179 T8851 T8850 punct ",",cytokines
R7180 T8852 T8850 prep including,cytokines
R7181 T8853 T8852 pobj TNF-α,including
R7182 T8854 T8853 punct ",",TNF-α
R7183 T8855 T8853 conj IL-1β,TNF-α
R7184 T8856 T8855 punct ",",IL-1β
R7185 T8857 T8855 cc and,IL-1β
R7186 T8858 T8855 conj IL-6,IL-1β
R7187 T8859 T8850 punct ",",cytokines
R7188 T8860 T8847 prep in,battery
R7189 T8861 T8862 compound brain,tissues
R7190 T8862 T8860 pobj tissues,in
R7191 T8863 T8841 prep after,induces
R7192 T8864 T8865 compound TBI,[
R7193 T8865 T8863 pobj [,after
R7194 T8866 T8868 quantmod 3,10
R7195 T8867 T8868 punct ",",10
R7196 T8868 T8871 nummod 10,]
R7197 T8869 T8870 punct ",",11
R7198 T8870 T8871 nummod 11,]
R7199 T8871 T8865 appos ],[
R7200 T8872 T8839 punct .,activated
R7201 T8873 T8874 poss Our,results
R7202 T8874 T8876 nsubj results,revealed
R7203 T8875 T8876 advmod also,revealed
R7204 T8876 T8876 ROOT revealed,revealed
R7205 T8877 T8880 mark that,induced
R7206 T8878 T8879 compound scratch,injury
R7207 T8879 T8880 nsubj injury,induced
R7208 T8880 T8876 ccomp induced,revealed
R7209 T8881 T8880 dobj elevation,induced
R7210 T8882 T8881 prep of,elevation
R7211 T8883 T8884 compound NF-κB,DNA
R7212 T8884 T8882 pobj DNA,of
R7213 T8885 T8886 amod binding,activity
R7214 T8886 T8880 conj activity,induced
R7215 T8887 T8886 punct ",",activity
R7216 T8888 T8886 conj overexpression,activity
R7217 T8889 T8888 prep of,overexpression
R7218 T8890 T8889 pobj MMP9,of
R7219 T8891 T8888 punct ",",overexpression
R7220 T8892 T8888 cc and,overexpression
R7221 T8893 T8894 amod proinflammatory,mediators
R7222 T8894 T8888 conj mediators,overexpression
R7223 T8895 T8894 acl mentioned,mediators
R7224 T8896 T8895 advmod above,mentioned
R7225 T8897 T8895 prep in,mentioned
R7226 T8898 T8899 amod cultured,astrocytes
R7227 T8899 T8897 pobj astrocytes,in
R7228 T8900 T8876 punct .,revealed
R7229 T8901 T8904 nsubjpass It,demonstrated
R7230 T8902 T8904 aux has,demonstrated
R7231 T8903 T8904 auxpass been,demonstrated
R7232 T8904 T8904 ROOT demonstrated,demonstrated
R7233 T8905 T8907 mark that,is
R7234 T8906 T8907 expl there,is
R7235 T8907 T8904 ccomp is,demonstrated
R7236 T8908 T8910 det an,loop
R7237 T8909 T8910 amod autoregulatory,loop
R7238 T8910 T8907 attr loop,is
R7239 T8911 T8910 prep among,loop
R7240 T8912 T8914 det these,mediators
R7241 T8913 T8914 amod proinflammatory,mediators
R7242 T8914 T8911 pobj mediators,among
R7243 T8915 T8904 punct .,demonstrated
R7244 T8916 T8922 prep For,are
R7245 T8917 T8916 pobj example,For
R7246 T8918 T8922 punct ",",are
R7247 T8919 T8922 nsubj TNF-α,are
R7248 T8920 T8919 cc and,TNF-α
R7249 T8921 T8919 conj IL-1β,TNF-α
R7250 T8922 T8922 ROOT are,are
R7251 T8923 T8924 amod potent,stimulators
R7252 T8924 T8922 attr stimulators,are
R7253 T8925 T8924 prep for,stimulators
R7254 T8926 T8925 pobj MMP9,for
R7255 T8927 T8924 prep in,stimulators
R7256 T8928 T8927 pobj astrocytes,in
R7257 T8929 T8933 nmod [,]
R7258 T8930 T8933 nummod 12,]
R7259 T8931 T8933 punct ",",]
R7260 T8932 T8933 nummod 13,]
R7261 T8933 T8937 nsubj ],induces
R7262 T8934 T8933 punct ",",]
R7263 T8935 T8933 cc and,]
R7264 T8936 T8933 conj IL-6,]
R7265 T8937 T8937 ROOT induces,induces
R7266 T8938 T8937 dobj overexpression,induces
R7267 T8939 T8938 prep of,overexpression
R7268 T8940 T8939 pobj MMP9,of
R7269 T8941 T8938 prep in,overexpression
R7270 T8942 T8944 amod human,carcinoma
R7271 T8943 T8944 compound colon,carcinoma
R7272 T8944 T8945 compound carcinoma,cells
R7273 T8945 T8941 pobj cells,in
R7274 T8946 T8948 nmod [,]
R7275 T8947 T8948 nummod 14,]
R7276 T8948 T8937 dobj ],induces
R7277 T8949 T8948 punct ",",]
R7278 T8950 T8948 cc and,]
R7279 T8951 T8948 conj TNF-α,]
R7280 T8952 T8951 cc and,TNF-α
R7281 T8953 T8951 conj IL-1β,TNF-α
R7282 T8954 T8956 advmod also,induce
R7283 T8955 T8956 aux can,induce
R7284 T8956 T8937 conj induce,induces
R7285 T8957 T8956 dobj activation,induce
R7286 T8958 T8957 prep of,activation
R7287 T8959 T8960 compound NF-κB,[
R7288 T8960 T8958 pobj [,of
R7289 T8961 T8960 nummod 15,[
R7290 T8962 T8960 punct ",",[
R7291 T8963 T8964 nummod 16,]
R7292 T8964 T8960 appos ],[
R7293 T8965 T8937 punct .,induces
R7294 T8966 T8968 det This,loop
R7295 T8967 T8968 amod autoregulatory,loop
R7296 T8968 T8970 nsubj loop,aggravates
R7297 T8969 T8970 advmod extremely,aggravates
R7298 T8970 T8970 ROOT aggravates,aggravates
R7299 T8971 T8973 det the,effect
R7300 T8972 T8973 amod damaging,effect
R7301 T8973 T8970 dobj effect,aggravates
R7302 T8974 T8973 prep of,effect
R7303 T8975 T8974 pobj inflammation,of
R7304 T8976 T8970 cc and,aggravates
R7305 T8977 T8970 conj induces,aggravates
R7306 T8978 T8979 amod secondary,injury
R7307 T8979 T8977 dobj injury,induces
R7308 T8980 T8977 prep to,induces
R7309 T8981 T8980 pobj brain,to
R7310 T8982 T8970 punct .,aggravates
R7311 T8983 T8984 nsubj It,is
R7312 T8984 T8984 ROOT is,is
R7313 T8985 T8987 det a,choice
R7314 T8986 T8987 amod good,choice
R7315 T8987 T8984 attr choice,is
R7316 T8988 T8987 prep for,choice
R7317 T8989 T8988 pcomp targeting,for
R7318 T8990 T8989 prep on,targeting
R7319 T8991 T8993 det an,factor
R7320 T8992 T8993 amod upstream,factor
R7321 T8993 T8990 pobj factor,on
R7322 T8994 T8995 aux to,prevent
R7323 T8995 T8993 acl prevent,factor
R7324 T8996 T8998 amod such,loop
R7325 T8997 T8998 amod autoregulatory,loop
R7326 T9025 T9024 punct ",",metabolites
R7327 T8998 T8995 dobj loop,prevent
R7328 T9026 T9029 nsubjpass which,involved
R7329 T9027 T9029 auxpass are,involved
R7330 T8999 T8998 prep after,loop
R7331 T9028 T9029 dep all,involved
R7332 T9029 T9024 relcl involved,metabolites
R7333 T9000 T8999 pobj TBI,after
R7334 T9030 T9029 prep in,involved
R7335 T9031 T9030 pobj TBI,in
R7336 T9001 T8984 punct .,is
R7337 T9032 T9006 punct .,proved
R7338 T9033 T9035 poss Our,study
R7339 T9002 T9003 amod Nrf2-ARE,pathway
R7340 T9034 T9035 amod previous,study
R7341 T9035 T9037 nsubj study,proved
R7342 T9036 T9037 aux has,proved
R7343 T9003 T9006 nsubjpass pathway,proved
R7344 T9037 T9037 ROOT proved,proved
R7345 T9038 T9039 det the,augmentation
R7346 T9039 T9037 dobj augmentation,proved
R7347 T9004 T9006 aux has,proved
R7348 T9040 T9039 prep of,augmentation
R7349 T9041 T9040 pobj Nrf2,of
R7350 T9042 T9039 prep in,augmentation
R7351 T9005 T9006 auxpass been,proved
R7352 T9043 T9044 compound brain,tissue
R7353 T9044 T9042 pobj tissue,in
R7354 T9045 T9037 prep after,proved
R7355 T9006 T9006 ROOT proved,proved
R7356 T9046 T9047 compound TBI,[
R7357 T9047 T9045 pobj [,after
R7358 T9007 T9008 aux to,be
R7359 T9048 T9047 nummod 17,[
R7360 T9049 T9047 conj ],[
R7361 T9008 T9006 xcomp be,proved
R7362 T9050 T9037 punct .,proved
R7363 T9051 T9052 amod Enhanced,level
R7364 T9052 T9052 ROOT level,level
R7365 T9009 T9011 det the,regulator
R7366 T9053 T9052 prep of,level
R7367 T9010 T9011 amod key,regulator
R7368 T9054 T9055 amod Nrf2,activates
R7369 T9055 T9053 pobj activates,of
R7370 T9056 T9055 dobj transcription,activates
R7371 T9011 T9008 attr regulator,be
R7372 T9057 T9056 prep of,transcription
R7373 T9058 T9059 det a,group
R7374 T9012 T9011 prep in,regulator
R7375 T9013 T9012 pcomp reducing,in
R7376 T9014 T9015 amod oxidative,stress
R7377 T9015 T9013 dobj stress,reducing
R7378 T9016 T9015 punct ",",stress
R7379 T9059 T9057 pobj group,of
R7380 T9060 T9059 prep of,group
R7381 T9017 T9018 amod inflammatory,damage
R7382 T9061 T9062 amod antioxidant,genes
R7383 T9062 T9060 pobj genes,of
R7384 T9063 T9062 punct ",",genes
R7385 T9018 T9015 conj damage,stress
R7386 T9064 T9065 amod such,as
R7387 T9065 T9062 prep as,genes
R7388 T9019 T9018 punct ",",damage
R7389 T9066 T9067 compound heme,oxygenase-1
R7390 T9020 T9018 cc and,damage
R7391 T9021 T9018 conj accumulation,damage
R7392 T9067 T9065 pobj oxygenase-1,as
R7393 T9068 T9069 punct (,HO-1
R7394 T9022 T9021 prep of,accumulation
R7395 T9069 T9067 appos HO-1,oxygenase-1
R7396 T9070 T9069 punct ),HO-1
R7397 T9071 T9067 cc and,oxygenase-1
R7398 T9023 T9024 amod toxic,metabolites
R7399 T9072 T9067 conj NAD,oxygenase-1
R7400 T9073 T9072 punct (,NAD
R7401 T9024 T9022 pobj metabolites,of
R7402 T9074 T9072 appos P,NAD
R7403 T9075 T9072 punct ),NAD
R7404 T9156 T9159 nsubj Depletion,induces
R7405 T9076 T9065 pobj H,as
R7406 T9077 T9055 punct :,activates
R7407 T9078 T9079 compound quinone,oxidoreductase-1
R7408 T9157 T9156 prep of,Depletion
R7409 T9079 T9052 appos oxidoreductase-1,level
R7410 T9080 T9079 punct (,oxidoreductase-1
R7411 T9081 T9079 appos NQO1,oxidoreductase-1
R7412 T9158 T9157 pobj Nrf2,of
R7413 T9082 T9079 punct ),oxidoreductase-1
R7414 T9083 T9052 punct ",",level
R7415 T9084 T9087 nsubj which,reduce
R7416 T9159 T9159 ROOT induces,induces
R7417 T9085 T9087 aux would,reduce
R7418 T9086 T9087 advmod subsequently,reduce
R7419 T9160 T9161 amod higher,expression
R7420 T9087 T9052 relcl reduce,level
R7421 T9088 T9089 det the,damage
R7422 T9089 T9087 dobj damage,reduce
R7423 T9090 T9089 prep in,damage
R7424 T9091 T9090 pobj brain,in
R7425 T9161 T9159 dobj expression,induces
R7426 T9092 T9094 nmod [,]
R7427 T9093 T9094 nummod 18,]
R7428 T9094 T9089 appos ],damage
R7429 T9095 T9052 punct .,level
R7430 T9096 T9097 compound Postinjury,administration
R7431 T9162 T9161 prep of,expression
R7432 T9097 T9107 nsubj administration,improves
R7433 T9098 T9097 prep of,administration
R7434 T9099 T9098 pobj SFN,of
R7435 T9163 T9164 amod proinflammatory,mediators
R7436 T9100 T9099 punct ",",SFN
R7437 T9164 T9162 pobj mediators,of
R7438 T9101 T9102 det an,inducer
R7439 T9102 T9099 appos inducer,SFN
R7440 T9165 T9159 prep in,induces
R7441 T9103 T9102 prep of,inducer
R7442 T9104 T9103 pobj Nrf2,of
R7443 T9105 T9107 punct ",",improves
R7444 T9166 T9165 pobj brain,in
R7445 T9106 T9107 advmod significantly,improves
R7446 T9107 T9107 ROOT improves,improves
R7447 T9108 T9109 amod spatial,memory
R7448 T9167 T9159 prep after,induces
R7449 T9109 T9107 dobj memory,improves
R7450 T9110 T9109 prep of,memory
R7451 T9111 T9110 pobj rat,of
R7452 T9168 T9169 compound TBI,[
R7453 T9112 T9107 cc and,improves
R7454 T9113 T9107 conj decreases,improves
R7455 T9114 T9115 det the,immunoreactivity
R7456 T9169 T9171 nmod [,]
R7457 T9115 T9113 dobj immunoreactivity,decreases
R7458 T9116 T9115 prep for,immunoreactivity
R7459 T9117 T9116 pobj 4-Hydroxynonenal,for
R7460 T9170 T9171 nummod 20,]
R7461 T9118 T9117 punct (,4-Hydroxynonenal
R7462 T9119 T9117 appos 4-HNE,4-Hydroxynonenal
R7463 T9120 T9117 punct ),4-Hydroxynonenal
R7464 T9171 T9167 pobj ],after
R7465 T9121 T9115 punct ",",immunoreactivity
R7466 T9122 T9123 det a,marker
R7467 T9123 T9115 appos marker,immunoreactivity
R7468 T9172 T9159 punct .,induces
R7469 T9124 T9123 prep of,marker
R7470 T9125 T9126 amod lipid,peroxidation
R7471 T9126 T9124 pobj peroxidation,of
R7472 T9173 T9177 advmod Here,revealed
R7473 T9127 T9113 punct ",",decreases
R7474 T9128 T9113 prep in,decreases
R7475 T9129 T9130 det the,cortex
R7476 T9130 T9128 pobj cortex,in
R7477 T9131 T9130 cc and,cortex
R7478 T9132 T9134 det the,subfield
R7479 T9174 T9177 punct ",",revealed
R7480 T9133 T9134 compound CA3,subfield
R7481 T9134 T9130 conj subfield,cortex
R7482 T9175 T9176 poss our,results
R7483 T9176 T9177 nsubj results,revealed
R7484 T9135 T9134 prep of,subfield
R7485 T9177 T9177 ROOT revealed,revealed
R7486 T9136 T9135 pobj hippocampus,of
R7487 T9137 T9113 prep after,decreases
R7488 T9178 T9192 mark that,was
R7489 T9138 T9139 compound TBI,[
R7490 T9139 T9141 nmod [,]
R7491 T9179 T9192 nsubj overexpression,was
R7492 T9140 T9141 nummod 19,]
R7493 T9141 T9137 pobj ],after
R7494 T9142 T9107 punct .,improves
R7495 T9180 T9179 prep of,overexpression
R7496 T9143 T9150 prep On,appear
R7497 T9144 T9146 det the,hand
R7498 T9181 T9180 pobj TNF-α,of
R7499 T9182 T9181 punct ",",TNF-α
R7500 T9145 T9146 amod other,hand
R7501 T9146 T9143 pobj hand,On
R7502 T9183 T9181 conj IL-1β,TNF-α
R7503 T9147 T9150 punct ",",appear
R7504 T9148 T9149 amod Nrf2-deficient,mice
R7505 T9184 T9183 punct ",",IL-1β
R7506 T9149 T9150 nsubj mice,appear
R7507 T9150 T9150 ROOT appear,appear
R7508 T9185 T9183 conj IL-6,IL-1β
R7509 T9151 T9152 advmod more,susceptible
R7510 T9152 T9150 oprd susceptible,appear
R7511 T9153 T9152 prep to,susceptible
R7512 T9186 T9185 punct ",",IL-6
R7513 T9154 T9153 pobj TBI,to
R7514 T9155 T9150 punct .,appear
R7515 T9187 T9185 cc and,IL-6
R7516 T9188 T9185 conj MMP9,IL-6
R7517 T9189 T9179 prep after,overexpression
R7518 T9190 T9191 compound scratch,injury
R7519 T9191 T9189 pobj injury,after
R7520 T9192 T9194 auxpass was,aggravated
R7521 T9253 T9253 ROOT found,found
R7522 T9193 T9194 advmod more,aggravated
R7523 T9254 T9255 aux to,be
R7524 T9255 T9253 xcomp be,found
R7525 T9256 T9255 acomp able,be
R7526 T9257 T9258 aux to,inhibit
R7527 T9258 T9256 xcomp inhibit,able
R7528 T9194 T9177 ccomp aggravated,revealed
R7529 T9259 T9261 compound IKK/I,phosphorylation
R7530 T9260 T9261 compound κB,phosphorylation
R7531 T9261 T9258 dobj phosphorylation,inhibit
R7532 T9195 T9194 prep in,aggravated
R7533 T9262 T9261 cc and,phosphorylation
R7534 T9263 T9267 nummod p65,translocation
R7535 T9196 T9199 amod cultured,astrocytes
R7536 T9264 T9267 amod NF-κB,translocation
R7537 T9265 T9267 nmod subunit,translocation
R7538 T9197 T9199 amod Nrf2,astrocytes
R7539 T9266 T9267 amod nuclear,translocation
R7540 T9267 T9261 conj translocation,phosphorylation
R7541 T9198 T9199 compound knockout,astrocytes
R7542 T9268 T9253 punct ",",found
R7543 T9269 T9270 advmod consequently,alleviating
R7544 T9270 T9253 advcl alleviating,found
R7545 T9199 T9195 pobj astrocytes,in
R7546 T9271 T9270 dobj NF-κB,alleviating
R7547 T9272 T9271 csubj signaling,NF-κB
R7548 T9273 T9275 nmod [,]
R7549 T9200 T9194 prep than,aggravated
R7550 T9274 T9275 nummod 21,]
R7551 T9275 T9272 dobj ],signaling
R7552 T9276 T9253 punct .,found
R7553 T9201 T9200 prep in,than
R7554 T9277 T9288 cc And,attenuated
R7555 T9278 T9279 amod NF-κB,activation
R7556 T9279 T9288 nsubjpass activation,attenuated
R7557 T9202 T9203 compound wildtype,astrocyetes
R7558 T9280 T9279 acl induced,activation
R7559 T9281 T9280 agent by,induced
R7560 T9282 T9281 pobj lipopolysaccharide,by
R7561 T9203 T9201 pobj astrocyetes,in
R7562 T9204 T9194 prep for,aggravated
R7563 T9205 T9207 det the,time
R7564 T9283 T9284 punct (,LPS
R7565 T9206 T9207 amod first,time
R7566 T9284 T9282 appos LPS,lipopolysaccharide
R7567 T9207 T9204 pobj time,for
R7568 T9285 T9282 punct ),lipopolysaccharide
R7569 T9286 T9288 aux could,attenuated
R7570 T9208 T9194 punct ",",aggravated
R7571 T9287 T9288 auxpass be,attenuated
R7572 T9288 T9288 ROOT attenuated,attenuated
R7573 T9289 T9288 agent by,attenuated
R7574 T9290 T9292 amod diverse,activators
R7575 T9291 T9292 amod Nrf2,activators
R7576 T9292 T9289 pobj activators,by
R7577 T9209 T9194 cc and,aggravated
R7578 T9293 T9292 punct ",",activators
R7579 T9294 T9295 amod such,as
R7580 T9295 T9292 prep as,activators
R7581 T9296 T9295 pobj SFN,as
R7582 T9210 T9215 nsubj overexpression,led
R7583 T9297 T9296 cc and,SFN
R7584 T9298 T9302 nmod curcumin,[
R7585 T9211 T9210 prep of,overexpression
R7586 T9299 T9300 punct (,CUR
R7587 T9300 T9298 appos CUR,curcumin
R7588 T9301 T9302 punct ),[
R7589 T9212 T9214 det these,mediators
R7590 T9213 T9214 amod proinflammatory,mediators
R7591 T9302 T9296 conj [,SFN
R7592 T9214 T9211 pobj mediators,of
R7593 T9303 T9304 nummod 22,]
R7594 T9215 T9194 conj led,aggravated
R7595 T9304 T9296 conj ],SFN
R7596 T9305 T9288 punct .,attenuated
R7597 T9306 T9311 advmod Furthermore,indicate
R7598 T9216 T9215 prep to,led
R7599 T9307 T9311 punct ",",indicate
R7600 T9308 T9310 poss our,studies
R7601 T9309 T9310 amod previous,studies
R7602 T9217 T9219 amod more,deaths
R7603 T9310 T9311 nsubj studies,indicate
R7604 T9218 T9219 compound astrocytes,deaths
R7605 T9311 T9311 ROOT indicate,indicate
R7606 T9312 T9316 mark that,induces
R7607 T9313 T9316 nsubj depletion,induces
R7608 T9219 T9216 pobj deaths,to
R7609 T9314 T9313 prep of,depletion
R7610 T9315 T9314 pobj Nrf2,of
R7611 T9220 T9177 punct .,revealed
R7612 T9316 T9311 ccomp induces,indicate
R7613 T9317 T9316 dobj augmentation,induces
R7614 T9318 T9317 prep of,augmentation
R7615 T9221 T9222 nsubj Data,obtained
R7616 T9319 T9320 amod NF-κB,activity
R7617 T9320 T9318 pobj activity,of
R7618 T9321 T9320 cc and,activity
R7619 T9222 T9222 ROOT obtained,obtained
R7620 T9322 T9323 amod inflammatory,response
R7621 T9323 T9320 conj response,activity
R7622 T9324 T9323 prep in,response
R7623 T9223 T9222 prep from,obtained
R7624 T9325 T9324 pobj lung,in
R7625 T9326 T9325 punct ",",lung
R7626 T9327 T9325 conj brain,lung
R7627 T9328 T9327 punct ",",brain
R7628 T9329 T9323 cc and,response
R7629 T9224 T9225 compound animal,studies
R7630 T9330 T9316 oprd intestine,induces
R7631 T9331 T9316 prep after,induces
R7632 T9332 T9333 compound TBI,[
R7633 T9225 T9223 pobj studies,from
R7634 T9333 T9331 pobj [,after
R7635 T9334 T9333 nummod 4,[
R7636 T9335 T9333 punct ",",[
R7637 T9336 T9333 appos 5,[
R7638 T9226 T9222 conj suggest,obtained
R7639 T9337 T9333 punct ",",[
R7640 T9338 T9339 nummod 23,]
R7641 T9227 T9228 det the,possibility
R7642 T9339 T9333 appos ],[
R7643 T9340 T9311 punct .,indicate
R7644 T9341 T9346 nsubj Results,confirmed
R7645 T9228 T9226 dobj possibility,suggest
R7646 T9342 T9341 prep from,Results
R7647 T9343 T9344 det this,study
R7648 T9229 T9236 mark that,achieved
R7649 T9344 T9342 pobj study,from
R7650 T9345 T9346 advmod further,confirmed
R7651 T9346 T9346 ROOT confirmed,confirmed
R7652 T9230 T9231 amod antioxidant,effect
R7653 T9347 T9348 amod such,relationship
R7654 T9348 T9349 nsubj relationship,existed
R7655 T9349 T9346 ccomp existed,confirmed
R7656 T9231 T9236 nsubjpass effect,achieved
R7657 T9232 T9231 prep of,effect
R7658 T9233 T9232 pobj Nrf2,of
R7659 T9234 T9236 aux may,achieved
R7660 T9350 T9349 prep in,existed
R7661 T9235 T9236 auxpass be,achieved
R7662 T9351 T9352 amod cultured,astrocytes
R7663 T9352 T9350 pobj astrocytes,in
R7664 T9236 T9228 acl achieved,possibility
R7665 T9353 T9349 prep after,existed
R7666 T9354 T9355 compound scratch,injury
R7667 T9237 T9236 agent by,achieved
R7668 T9355 T9353 pobj injury,after
R7669 T9356 T9346 punct .,confirmed
R7670 T9357 T9358 amod Enhanced,activation
R7671 T9238 T9237 pobj suppression,by
R7672 T9358 T9363 nsubjpass activation,discovered
R7673 T9359 T9358 prep of,activation
R7674 T9360 T9359 pobj NF-κB,of
R7675 T9361 T9363 auxpass is,discovered
R7676 T9362 T9363 advmod also,discovered
R7677 T9363 T9363 ROOT discovered,discovered
R7678 T9364 T9363 prep in,discovered
R7679 T9239 T9238 prep of,suppression
R7680 T9365 T9364 pobj lung,in
R7681 T9366 T9364 punct ",",in
R7682 T9367 T9364 conj macrophages,in
R7683 T9240 T9241 amod proinflammatory,pathways
R7684 T9368 T9367 punct ",",macrophages
R7685 T9369 T9367 cc and,macrophages
R7686 T9370 T9372 amod mouse,fibroblasts
R7687 T9241 T9239 pobj pathways,of
R7688 T9371 T9372 amod embryonic,fibroblasts
R7689 T9372 T9367 conj fibroblasts,macrophages
R7690 T9242 T9244 nsubjpass which,mediated
R7691 T9373 T9372 prep of,fibroblasts
R7692 T9374 T9375 amod Nrf2-deficient,mice
R7693 T9375 T9373 pobj mice,of
R7694 T9243 T9244 auxpass are,mediated
R7695 T9376 T9363 prep after,discovered
R7696 T9377 T9378 amod experimental,sepsis
R7697 T9244 T9241 relcl mediated,pathways
R7698 T9378 T9376 pobj sepsis,after
R7699 T9379 T9381 nmod [,]
R7700 T9245 T9244 agent by,mediated
R7701 T9380 T9381 nummod 24,]
R7702 T9246 T9247 amod NF-κB,signaling
R7703 T9247 T9245 pcomp signaling,by
R7704 T9381 T9381 ROOT ],]
R7705 T9382 T9363 punct .,discovered
R7706 T9248 T9222 punct .,obtained
R7707 T9383 T9387 advmod Interestingly,reported
R7708 T9384 T9387 punct ",",reported
R7709 T9385 T9387 nsubjpass it,reported
R7710 T9249 T9253 nsubjpass Administration,found
R7711 T9386 T9387 auxpass is,reported
R7712 T9387 T9387 ROOT reported,reported
R7713 T9388 T9391 mark that,inhibit
R7714 T9250 T9249 prep of,Administration
R7715 T9389 T9391 nsubj NF-κB,inhibit
R7716 T9251 T9250 pobj SFN,of
R7717 T9390 T9391 aux can,inhibit
R7718 T9391 T9387 ccomp inhibit,reported
R7719 T9392 T9391 dobj Nrf2,inhibit
R7720 T9252 T9253 auxpass is,found
R7721 T9393 T9391 prep at,inhibit
R7722 T9394 T9395 amod transcriptional,level
R7723 T9411 T9413 det the,domain
R7724 T9395 T9393 pobj level,at
R7725 T9396 T9387 punct .,reported
R7726 T9397 T9399 nmod NF-κB,subunit
R7727 T9398 T9397 nummod p65,NF-κB
R7728 T9399 T9400 nsubj subunit,repressed
R7729 T9400 T9400 ROOT repressed,repressed
R7730 T9401 T9403 det the,pathway
R7731 T9412 T9413 compound CH1-KIX,domain
R7732 T9402 T9403 amod Nrf2-ARE,pathway
R7733 T9403 T9400 dobj pathway,repressed
R7734 T9404 T9400 prep at,repressed
R7735 T9413 T9410 pobj domain,with
R7736 T9405 T9406 amod transcriptional,level
R7737 T9406 T9404 pobj level,at
R7738 T9407 T9400 prep by,repressed
R7739 T9408 T9409 amod competitive,interaction
R7740 T9414 T9413 prep of,domain
R7741 T9409 T9407 pobj interaction,by
R7742 T9410 T9409 prep with,interaction
R7743 T9415 T9414 pobj CBP,of
R7744 T9416 T9415 cc or,CBP
R7745 T9417 T9419 amod local,hypoacetylation
R7746 T9449 T9446 punct ),kinase
R7747 T9418 T9419 compound histone,hypoacetylation
R7748 T9450 T9427 conj pathway,indicate
R7749 T9419 T9420 compound hypoacetylation,[
R7750 T9420 T9415 conj [,CBP
R7751 T9451 T9453 nmod [,]
R7752 T9452 T9453 nummod 26,]
R7753 T9421 T9422 nummod 25,]
R7754 T9453 T9450 dobj ],pathway
R7755 T9454 T9427 punct .,indicate
R7756 T9422 T9420 appos ],[
R7757 T9455 T9458 nsubjpass It,confirmed
R7758 T9456 T9458 aux has,confirmed
R7759 T9423 T9400 punct .,repressed
R7760 T9457 T9458 auxpass been,confirmed
R7761 T9458 T9458 ROOT confirmed,confirmed
R7762 T9459 T9463 mark that,detected
R7763 T9424 T9426 predet All,findings
R7764 T9460 T9463 nsubjpass Nrf2,detected
R7765 T9425 T9426 det these,findings
R7766 T9426 T9427 nsubj findings,indicate
R7767 T9461 T9463 auxpass is,detected
R7768 T9462 T9463 advmod mainly,detected
R7769 T9427 T9427 ROOT indicate,indicate
R7770 T9463 T9458 ccomp detected,confirmed
R7771 T9464 T9463 prep in,detected
R7772 T9428 T9431 det the,crosstalk
R7773 T9465 T9464 pobj nucleus,in
R7774 T9466 T9465 prep of,nucleus
R7775 T9467 T9466 pobj astrocytes,of
R7776 T9468 T9463 prep after,detected
R7777 T9469 T9470 compound TBI,[
R7778 T9429 T9431 amod potential,crosstalk
R7779 T9470 T9468 pobj [,after
R7780 T9471 T9472 nummod 18,]
R7781 T9472 T9470 appos ],[
R7782 T9430 T9431 compound complicate,crosstalk
R7783 T9473 T9458 punct .,confirmed
R7784 T9474 T9496 prep In,reasoned
R7785 T9475 T9474 pobj view,In
R7786 T9431 T9427 dobj crosstalk,indicate
R7787 T9476 T9475 prep of,view
R7788 T9477 T9478 det the,fact
R7789 T9432 T9431 prep between,crosstalk
R7790 T9478 T9476 pobj fact,of
R7791 T9479 T9481 mark that,is
R7792 T9480 T9481 nsubj Nrf2,is
R7793 T9433 T9432 pobj NF-κB,between
R7794 T9481 T9478 acl is,fact
R7795 T9482 T9484 det a,factor
R7796 T9483 T9484 compound transcription,factor
R7797 T9434 T9433 cc and,NF-κB
R7798 T9484 T9481 attr factor,is
R7799 T9485 T9487 nsubj which,take
R7800 T9435 T9433 conj Nrf2,NF-κB
R7801 T9486 T9487 aux should,take
R7802 T9487 T9484 relcl take,factor
R7803 T9488 T9487 dobj function,take
R7804 T9436 T9433 punct ",",NF-κB
R7805 T9489 T9490 advmod mainly,in
R7806 T9490 T9487 prep in,take
R7807 T9437 T9440 nsubjpass which,regulated
R7808 T9491 T9490 pobj nucleus,in
R7809 T9492 T9496 punct ",",reasoned
R7810 T9493 T9496 nsubjpass it,reasoned
R7811 T9438 T9440 aux may,regulated
R7812 T9494 T9496 aux can,reasoned
R7813 T9495 T9496 auxpass be,reasoned
R7814 T9496 T9496 ROOT reasoned,reasoned
R7815 T9439 T9440 auxpass be,regulated
R7816 T9497 T9500 mark that,be
R7817 T9498 T9500 nsubj astrocytes,be
R7818 T9499 T9500 aux may,be
R7819 T9440 T9431 relcl regulated,crosstalk
R7820 T9500 T9496 ccomp be,reasoned
R7821 T9501 T9502 nummod one,kind
R7822 T9441 T9440 agent by,regulated
R7823 T9502 T9500 attr kind,be
R7824 T9503 T9502 prep of,kind
R7825 T9504 T9505 compound respondent,cells
R7826 T9505 T9503 pobj cells,of
R7827 T9506 T9502 prep in,kind
R7828 T9507 T9506 pobj activation,in
R7829 T9442 T9446 det the,kinase
R7830 T9508 T9507 prep of,activation
R7831 T9509 T9510 compound Nrf2-ARE,pathway
R7832 T9510 T9508 pobj pathway,of
R7833 T9511 T9500 prep after,be
R7834 T9443 T9446 amod upstream,kinase
R7835 T9512 T9511 pobj TBI,after
R7836 T9513 T9496 punct .,reasoned
R7837 T9444 T9445 amod mitogen-activated,protein
R7838 T9514 T9515 amod Previous,study
R7839 T9515 T9516 nsubj study,identified
R7840 T9445 T9446 compound protein,kinase
R7841 T9516 T9516 ROOT identified,identified
R7842 T9517 T9518 det the,expression
R7843 T9518 T9516 dobj expression,identified
R7844 T9446 T9441 pobj kinase,by
R7845 T9519 T9518 prep of,expression
R7846 T9520 T9519 pobj TNF-α,of
R7847 T9447 T9448 punct (,MAPKs
R7848 T9521 T9520 punct ",",TNF-α
R7849 T9522 T9520 conj IL-1β,TNF-α
R7850 T9523 T9522 punct ",",IL-1β
R7851 T9448 T9446 appos MAPKs,kinase
R7852 T9524 T9522 cc and,IL-1β
R7853 T9525 T9522 conj IL-6,IL-1β
R7854 T9526 T9516 prep in,identified
R7855 T9546 T9549 amod middle,occlusion
R7856 T9527 T9528 amod cultured,astrocytes
R7857 T9528 T9526 pobj astrocytes,in
R7858 T9529 T9516 prep after,identified
R7859 T9547 T9549 amod cerebral,occlusion
R7860 T9548 T9549 compound artery,occlusion
R7861 T9549 T9545 pobj occlusion,after
R7862 T9530 T9529 pobj treatment,after
R7863 T9531 T9530 prep with,treatment
R7864 T9550 T9554 punct ",",observed
R7865 T9532 T9531 pobj LPS,with
R7866 T9533 T9530 cc or,treatment
R7867 T9551 T9552 amod MMP9-positive,astrocytes
R7868 T9534 T9535 compound oxyhemoglobin,[
R7869 T9535 T9516 dobj [,identified
R7870 T9536 T9535 nummod 27,[
R7871 T9552 T9554 nsubjpass astrocytes,observed
R7872 T9537 T9535 punct ",",[
R7873 T9538 T9539 nummod 28,]
R7874 T9553 T9554 auxpass were,observed
R7875 T9554 T9543 ccomp observed,revealed
R7876 T9539 T9535 appos ],[
R7877 T9540 T9516 punct .,identified
R7878 T9541 T9542 det Another,study
R7879 T9542 T9543 nsubj study,revealed
R7880 T9543 T9543 ROOT revealed,revealed
R7881 T9555 T9554 prep in,observed
R7882 T9544 T9554 mark that,observed
R7883 T9545 T9554 prep after,observed
R7884 T9556 T9557 compound brain,tissues
R7885 T9557 T9555 pobj tissues,in
R7886 T9558 T9554 agent by,observed
R7887 T9559 T9560 compound immunohistochemistry,[
R7888 T9560 T9558 pobj [,by
R7889 T9561 T9562 nummod 29,]
R7890 T9643 T9642 pobj TNF-α,of
R7891 T9562 T9560 appos ],[
R7892 T9644 T9643 punct ",",TNF-α
R7893 T9645 T9643 conj IL-1β,TNF-α
R7894 T9563 T9543 punct .,revealed
R7895 T9646 T9645 punct ",",IL-1β
R7896 T9647 T9645 conj IL-6,IL-1β
R7897 T9648 T9647 punct ",",IL-6
R7898 T9564 T9565 det Those,results
R7899 T9565 T9566 nsubj results,indicate
R7900 T9566 T9566 ROOT indicate,indicate
R7901 T9649 T9647 cc and,IL-6
R7902 T9567 T9568 det the,role
R7903 T9650 T9647 conj MMP9,IL-6
R7904 T9651 T9634 advcl resulting,induced
R7905 T9568 T9566 dobj role,indicate
R7906 T9652 T9651 prep in,resulting
R7907 T9653 T9655 amod more,deaths
R7908 T9569 T9568 prep of,role
R7909 T9654 T9655 compound cell,deaths
R7910 T9655 T9652 pobj deaths,in
R7911 T9656 T9655 prep in,deaths
R7912 T9570 T9569 pobj astrocytes,of
R7913 T9657 T9656 pobj astrocytes,in
R7914 T9658 T9651 prep after,resulting
R7915 T9571 T9570 prep in,astrocytes
R7916 T9659 T9660 compound scratch,injury
R7917 T9660 T9658 pobj injury,after
R7918 T9661 T9634 punct .,induced
R7919 T9572 T9573 amod inflammatory,process
R7920 T9662 T9663 det These,results
R7921 T9663 T9664 nsubj results,suggest
R7922 T9573 T9571 pobj process,in
R7923 T9664 T9664 ROOT suggest,suggest
R7924 T9665 T9668 mark that,be
R7925 T9574 T9568 prep after,role
R7926 T9666 T9668 nsubj Nrf2,be
R7927 T9667 T9668 aux may,be
R7928 T9668 T9664 ccomp be,suggest
R7929 T9669 T9671 det an,target
R7930 T9670 T9671 amod important,target
R7931 T9671 T9668 attr target,be
R7932 T9575 T9576 compound brain,injury
R7933 T9672 T9671 prep for,target
R7934 T9673 T9674 amod anti-inflammatory,therapy
R7935 T9674 T9672 pobj therapy,for
R7936 T9576 T9574 pobj injury,after
R7937 T9675 T9668 prep after,be
R7938 T9676 T9675 pobj TBI,after
R7939 T9577 T9566 punct .,indicate
R7940 T9677 T9664 punct .,suggest
R7941 T9578 T9583 cc But,is
R7942 T9579 T9583 prep till,is
R7943 T9580 T9579 pcomp now,till
R7944 T9581 T9583 punct ",",is
R7945 T9582 T9583 expl there,is
R7946 T9583 T9583 ROOT is,is
R7947 T9584 T9585 det no,study
R7948 T9585 T9583 attr study,is
R7949 T9586 T9585 acl focused,study
R7950 T9587 T9586 prep on,focused
R7951 T9588 T9589 det the,relationship
R7952 T9589 T9587 pobj relationship,on
R7953 T9590 T9589 prep among,relationship
R7954 T9591 T9590 pobj astrocytes,among
R7955 T9592 T9589 punct ",",relationship
R7956 T9593 T9589 appos Nrf2,relationship
R7957 T9594 T9593 punct ",",Nrf2
R7958 T9595 T9589 cc and,relationship
R7959 T9596 T9597 amod proinflammatory,mediators
R7960 T9597 T9589 conj mediators,relationship
R7961 T9598 T9586 prep after,focused
R7964 T9599 T9598 pobj TBI,after
R7967 T9600 T9583 punct .,is
R7974 T9601 T9602 poss Our,results
R7985 T9602 T9603 nsubj results,demonstrated
R7989 T9603 T9603 ROOT demonstrated,demonstrated
R7991 T9604 T9606 det the,expression
R7994 T9605 T9606 amod upregulated,expression
R7995 T9606 T9603 dobj expression,demonstrated
R7996 T9607 T9606 prep of,expression
R7998 T9608 T9607 pobj TNF-α,of
R8000 T9609 T9608 punct ",",TNF-α
R8003 T9610 T9608 conj IL-1β,TNF-α
R8004 T9611 T9610 punct ",",IL-1β
R8005 T9612 T9610 conj IL-6,IL-1β
R8006 T9613 T9612 punct ",",IL-6
R8007 T9614 T9612 cc and,IL-6
R8009 T9615 T9612 conj MMP9,IL-6
R8014 T9616 T9615 prep in,MMP9
R8017 T9617 T9618 compound Nrf2,knockout
R8020 T9618 T9616 pobj knockout,in
R8024 T9619 T9606 appos astrocytes,expression
R8031 T9620 T9603 prep after,demonstrated
R8034 T9621 T9622 compound scratch,injury
R8036 T9622 T9620 pobj injury,after
R8038 T9623 T9622 prep for,injury
R8039 T9624 T9626 det the,time
R8043 T9625 T9626 amod first,time
R8047 T9626 T9623 pobj time,for
R8051 T9627 T9603 punct .,demonstrated
R8054 T9628 T9634 prep In,induced
R8055 T9629 T9628 pobj conclusion,In
R8057 T9630 T9634 punct ",",induced
R8058 T9631 T9634 nsubj depletion,induced
R8062 T9632 T9631 prep of,depletion
R8063 T9633 T9632 pobj Nrf2,of
R8064 T9634 T9634 ROOT induced,induced
R8065 T9635 T9636 det the,activation
R8067 T9636 T9634 dobj activation,induced
R8069 T9637 T9636 prep of,activation
R8072 T9638 T9637 pobj NF-κB,of
R8073 T9639 T9636 cc and,activation
R8074 T9640 T9641 det the,expression
R8075 T9641 T9636 conj expression,activation
R8082 T9642 T9641 prep of,expression